cystine and n,n-diacetylcystine

cystine has been researched along with n,n-diacetylcystine in 11 studies

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19901 (9.09)18.7374
1990's1 (9.09)18.2507
2000's7 (63.64)29.6817
2010's0 (0.00)24.3611
2020's2 (18.18)2.80

Authors

AuthorsStudies
Bässler, KH; Böhler, S; Neuhäuser-Berthold, M; Virmani, K; Wagner, K1
Bergstrand, H; Jansson, AH; Matuseviciene, G; Pierrou, S; Särnstrand, B; Scheynius, A1
Andersson, T; Boräng, S; Larsson, M; Lundeberg, J; Odeberg, J; Thelin, A1
Bergstrand, H; Jansson, AH; Ostlund-Lindqvist, AM; Pettersson, K; Särnstrand, B; Wågberg, M; Westerlund, C1
Doggrell, SA1
Bergstrand, H; Pettersson, K1
Lin, Y; Ren, XC; Wang, P; Wu, XM; Yu, J1
Johansson, K; Jungersten, L; Kalies, I; Kjerrulf, M; Långström, G; Lenkei, R; Lind, L; Pettersson, K; Walldius, G1
Abrahamsson, T; Carrier, M; Eliasson, UB; Kengatharan, KM; Pettersson, KS; Wågberg, M1
Adamo, V; Bonnabry, P; Bouchoud, L; Sadeghipour, F; Schwebel, H; Sommer, I1
Kim, D; Ku, DN; Shea, SM1

Reviews

1 review(s) available for cystine and n,n-diacetylcystine

ArticleYear
The antiatherogenic effect of DiNAC: experimental findings supporting immunomodulation as a new treatment for atherosclerosis related diseases.
    Cardiovascular drug reviews, 2003,Summer, Volume: 21, Issue:2

    Topics: Adjuvants, Immunologic; Animals; Antioxidants; Arteriosclerosis; Clinical Trials as Topic; Cystine; Drug Evaluation, Preclinical; Endothelium, Vascular; Humans; Hypersensitivity, Delayed; Quantitative Structure-Activity Relationship; Vasodilation

2003

Trials

1 trial(s) available for cystine and n,n-diacetylcystine

ArticleYear
The new oral immunomodulating drug DiNAC induces brachial artery vasodilatation at rest and during hyperemia in hypercholesterolemic subjects, likely by a nitric oxide-dependent mechanism.
    Atherosclerosis, 2008, Volume: 196, Issue:1

    Topics: Acetylcysteine; Aged; Brachial Artery; Cells, Cultured; Cystine; Dose-Response Relationship, Drug; Double-Blind Method; Endothelial Cells; Female; Humans; Hypercholesterolemia; Hyperemia; Immunologic Factors; Leukocytes; Male; Middle Aged; Nitric Oxide; Nitric Oxide Synthase Type III; Postmenopause; Ultrasonography; Umbilical Veins; Vasodilation; Vasodilator Agents

2008

Other Studies

9 other study(ies) available for cystine and n,n-diacetylcystine

ArticleYear
[Cysteine in parenteral nutrition: comparative study of N-acetyl-cysteine and N,N-diacetylcystine in the rat model].
    Infusionstherapie (Basel, Switzerland), 1988, Volume: 15, Issue:2

    Topics: Acetylcysteine; Animals; Cysteine; Cystine; Liver; Male; Parenteral Nutrition, Total; Rats; Rats, Inbred Strains

1988
N,N'-Diacetyl-L-cystine-the disulfide dimer of N-acetylcysteine-is a potent modulator of contact sensitivity/delayed type hypersensitivity reactions in rodents.
    The Journal of pharmacology and experimental therapeutics, 1999, Volume: 288, Issue:3

    Topics: Acetylcysteine; Adjuvants, Immunologic; Animals; CD8-Positive T-Lymphocytes; Cystine; Dermatitis, Contact; Dinitrofluorobenzene; Ear; Female; Fluorescein-5-isothiocyanate; Foot; Granuloma; Hypersensitivity, Delayed; Immunohistochemistry; Lymphocyte Count; Male; Mice; Mice, Inbred BALB C; Mice, Inbred Strains; Oxazolone; Rabbits; Serum Albumin, Bovine

1999
Monitoring of the subtraction process in solid-phase representational difference analysis: characterization of a candidate drug.
    Gene, 2001, Jun-27, Volume: 271, Issue:2

    Topics: Arteriosclerosis; Cell Line; Cystine; DNA, Complementary; Gene Expression Profiling; Gene Expression Regulation; Humans; Nucleic Acid Hybridization; Polymerase Chain Reaction; Reproducibility of Results; Reverse Transcriptase Polymerase Chain Reaction; Software

2001
N,N'-diacetyl-L-cystine (DiNAC), the disulphide dimer of N-acetylcysteine, inhibits atherosclerosis in WHHL rabbits: evidence for immunomodulatory agents as a new approach to prevent atherosclerosis.
    The Journal of pharmacology and experimental therapeutics, 2001, Volume: 299, Issue:1

    Topics: Acetylcysteine; Adjuvants, Immunologic; Animals; Antioxidants; Arteriosclerosis; Cholesterol; Cystine; Dermatitis, Contact; Disulfides; Male; Mice; Mice, Inbred BALB C; Oxazolone; Probucol; Rabbits; Receptors, LDL; Structure-Activity Relationship; Triglycerides

2001
Immunomodulation with DiNAC-- a new approach to the treatment of atherosclerosis?
    Expert opinion on investigational drugs, 2002, Volume: 11, Issue:5

    Topics: Adjuvants, Immunologic; Animals; Arteriosclerosis; Benzhydryl Compounds; Cystine; Dermatitis, Contact; Mice; Mice, Inbred BALB C; Phenols; Probucol; Rabbits

2002
Influence of N,N'-diacetyl-L-cystine on D-galactosamine/lipopolysaccharide induced immunological liver failure in mice.
    Yao xue xue bao = Acta pharmaceutica Sinica, 2004, Volume: 39, Issue:10

    Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Bilirubin; CD4 Antigens; CD8 Antigens; Cell Differentiation; Cell Proliferation; Cystine; Liver; Liver Failure, Acute; Male; Mice; Mice, Inbred BALB C; T-Lymphocytes

2004
N,N-diacetyl-L-cystine improves endothelial function in atherosclerotic Watanabe heritable hyperlipidaemic rabbits.
    Basic & clinical pharmacology & toxicology, 2007, Volume: 100, Issue:1

    Topics: Acetylcholine; Administration, Oral; Animals; Aorta; Atherosclerosis; Cystine; Disease Models, Animal; Endothelium, Vascular; Immunologic Factors; In Vitro Techniques; Male; Pulsatile Flow; Rabbits; Vasodilation; Water Supply

2007
Stability of
    Nutrients, 2020, Jun-21, Volume: 12, Issue:6

    Topics: Acetylcysteine; Amino Acids; Biological Availability; Cysteine; Cystine; Drug Industry; Drug Stability; Drug Storage; Humans; Infant Nutritional Physiological Phenomena; Infant, Newborn; Infant, Premature; Nutritional Requirements; Oxidation-Reduction; Oxygen; Parenteral Nutrition; Parenteral Nutrition Solutions

2020
Lysis of arterial thrombi by perfusion of N,N'-Diacetyl-L-cystine (DiNAC).
    PloS one, 2021, Volume: 16, Issue:2

    Topics: Animals; Cystine; Fibrinolytic Agents; Swine; Thrombolytic Therapy; Thrombosis; Thrombotic Stroke

2021