cystine has been researched along with erastin in 9 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 3 (33.33) | 24.3611 |
| 2020's | 6 (66.67) | 2.80 |
| Authors | Studies |
|---|---|
| Dixon, SJ; Gleason, CE; Hayano, M; Lee, ED; Patel, DN; Skouta, R; Slusher, BS; Stockwell, BR; Tatonetti, NP; Thomas, AG; Welsch, M | 1 |
| Corn, CK; Hayano, M; Pagano, NC; Stockwell, BR; Yang, WS | 1 |
| Jang, HJ; Kim, EH; Park, JY; Roh, JL; Shin, D | 1 |
| Bossa, N; Chen, PH; Chi, JT; Ding, CC; Lin, CC; Mathey-Prevot, B; Pan, S; Wu, J; Xu, Y; Yang, WH | 1 |
| Alvarez, JV; Chi, JT; Force, J; Hong, L; Lin, CC; Lin, YT; Mabe, NW; Marks, JR; Sun, T; Tang, X; Yang, WH; Yao, TP | 1 |
| Alwaseem, H; Birsoy, K; Garcia-Bermudez, J; La, K; Molina, H; Pratt, DA; Soula, M; Weber, RA; Yen, F; Zilka, O | 1 |
| Gan, B; Koppula, P; Zhuang, L | 1 |
| Bottelin, M; François, C; Galmiche, A; Godin, C; Hémon, A; Lailler, C; Louandre, C; Morel, V; Saidak, Z | 1 |
| Du, J; Hu, W; Huang, Z; Li, Y; Tong, X; Wang, X; Wang, Y; Xia, J; Zhou, Y | 1 |
1 review(s) available for cystine and erastin
| Article | Year |
|---|---|
Cystine transporter SLC7A11/xCT in cancer: ferroptosis, nutrient dependency, and cancer therapy.
Topics: Amino Acid Transport System y+; Antineoplastic Agents; Cystine; DNA Methylation; Ferroptosis; Gene Expression Regulation, Neoplastic; Glucose; Glutamine; Glutathione; Histones; Humans; Molecular Targeted Therapy; Neoplasms; Piperazines; Signal Transduction; Sorafenib; Sulfasalazine | 2021 |
8 other study(ies) available for cystine and erastin
| Article | Year |
|---|---|
Pharmacological inhibition of cystine-glutamate exchange induces endoplasmic reticulum stress and ferroptosis.
Topics: 20-Hydroxysteroid Dehydrogenases; Amino Acid Transport System y+; Apoptosis; Biomarkers; Cell Line; Cell Line, Tumor; Cell Proliferation; Cell Separation; Cystine; Endoplasmic Reticulum Stress; Glutamic Acid; Humans; Iron; Niacinamide; Phenylurea Compounds; Piperazines; Protein Kinase Inhibitors; Sequence Analysis, RNA; Sorafenib; Structure-Activity Relationship; Transcriptome; Up-Regulation | 2014 |
Loss of cysteinyl-tRNA synthetase (CARS) induces the transsulfuration pathway and inhibits ferroptosis induced by cystine deprivation.
Topics: Amino Acyl-tRNA Synthetases; Animals; Antineoplastic Agents; Apoptosis; Biosynthetic Pathways; Cystine; Drug Resistance, Neoplasm; Gene Knockdown Techniques; Glutamic Acid; Humans; PC12 Cells; Piperazines; Rats; Reactive Oxygen Species; Serine; Signal Transduction | 2016 |
Induction of ferroptotic cell death for overcoming cisplatin resistance of head and neck cancer.
Topics: Amino Acid Transport System y+; Animals; Antineoplastic Agents; Cell Death; Cell Line, Tumor; Cisplatin; Cystine; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Glutamine; Glutathione; Head and Neck Neoplasms; Humans; Male; Mice, Inbred BALB C; Mice, Nude; Piperazines; Reactive Oxygen Species; RNA Interference; Sulfasalazine; Transfection; Xenograft Model Antitumor Assays | 2016 |
Kinome screen of ferroptosis reveals a novel role of ATM in regulating iron metabolism.
Topics: Ataxia Telangiectasia Mutated Proteins; Cation Transport Proteins; Cell Line, Tumor; Cystine; Ferroptosis; Gene Expression Regulation; Humans; Iron; Models, Biological; Piperazines; Protein Kinases; Proteome; RNA, Messenger; Transcription, Genetic | 2020 |
RIPK3 upregulation confers robust proliferation and collateral cystine-dependence on breast cancer recurrence.
Topics: Adaptor Proteins, Signal Transducing; Animals; Cell Proliferation; Cystine; Epigenesis, Genetic; Female; Gene Expression Regulation, Neoplastic; Mammary Neoplasms, Animal; Mitosis; Neoplasm Recurrence, Local; Piperazines; Receptor-Interacting Protein Serine-Threonine Kinases; Signal Transduction; Transcriptome; Tumor Stem Cell Assay; Tumor Suppressor Protein p53; Up-Regulation; YAP-Signaling Proteins | 2020 |
Metabolic determinants of cancer cell sensitivity to canonical ferroptosis inducers.
Topics: Antineoplastic Agents; Antioxidants; Biopterins; Carbolines; Cell Line, Tumor; Cell Proliferation; Cystine; Dose-Response Relationship, Drug; Ferroptosis; Folic Acid Antagonists; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Humans; Jurkat Cells; Lipid Peroxidation; Methotrexate; Oxidative Stress; Phospholipid Hydroperoxide Glutathione Peroxidase; Piperazines; Reactive Oxygen Species; Signal Transduction; Tetrahydrofolate Dehydrogenase; Vitamin E | 2020 |
SLC7A11 as a biomarker and therapeutic target in HPV-positive head and neck Squamous Cell Carcinoma.
Topics: Acetylcysteine; Amino Acid Transport System y+; Biological Transport, Active; Biomarkers; Cell Line, Tumor; Cystine; Ferroptosis; Gene Expression Regulation, Neoplastic; Glutathione; Head and Neck Neoplasms; Human papillomavirus 16; Humans; Oncogene Proteins, Viral; Papillomavirus E7 Proteins; Papillomavirus Infections; Phospholipid Hydroperoxide Glutathione Peroxidase; Piperazines; Repressor Proteins; RNA-Seq; Single-Cell Analysis; Squamous Cell Carcinoma of Head and Neck | 2020 |
CISD3 inhibition drives cystine-deprivation induced ferroptosis.
Topics: Animals; Cell Line, Tumor; Cell Survival; Cystine; Disease Progression; Ferroptosis; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Gene Knockdown Techniques; Glutamine; Homeostasis; Humans; Iron; Iron-Sulfur Proteins; Lipid Peroxides; Mice, Nude; Mitochondria; Mitochondrial Dynamics; Mitochondrial Proteins; Mitophagy; Neoplasms; Organophosphorus Compounds; Piperazines; Ubiquinone; Xenograft Model Antitumor Assays | 2021 |