cystine and buthionine sulfoximine

cystine has been researched along with buthionine sulfoximine in 44 studies

Research

Studies (44)

TimeframeStudies, this research(%)All Research%
pre-19905 (11.36)18.7374
1990's22 (50.00)18.2507
2000's11 (25.00)29.6817
2010's5 (11.36)24.3611
2020's1 (2.27)2.80

Authors

AuthorsStudies
Brimacombe, KR; Dulcey, AE; Goldsborough, AS; Gottesman, MM; Griffiths, G; Hall, MD; Handley, MD; Kannan, P; Pluchino, KM1
Lawrence, DA; Messina, JP1
Das, SK; Fanburg, BL; White, AC1
Hill, L; Lailey, AF; Lawston, IW; Stanton, D; Upshall, DG1
Boyd, MR; Ravindranath, V1
Atzori, L; Cotgreave, I; Dypbukt, JM; Edman, CC; Grafström, RC; Moldéus, P; Sundqvist, K1
Broome, JD; Chen, PC; Gaetjens, E1
Griffith, OW; Meister, A1
Brodie, AE; Reed, DJ1
Green, JA; Hamilton, TC; Ozols, RF; Rogan, AM; Vistica, DT; Young, RC1
Griffith, OW1
Graham, A; Wood, JL1
Gardiner, CS; Reed, DJ1
Graham, A; O'Leary, VJ; Stone, D; Wood, JL2
Ishita, S; Kato, S; Mawatari, K; Sugawara, K1
Cotgreave, IA; Schuppe-Koistinen, I1
Atzori, L; Dypbukt, JM; Grafström, RC; Hybbinette, SS; Moldéus, P1
Kang, YJ1
Boustani, MR; Fanburg, BL; Hertig, IA; Maloney, EK; White, AC1
Duval, D; Froissard, P; Monrocq, H1
Benathan, M1
Bruchovsky, N; Buckley, AR; Buckley, DJ; Gout, PW; Kang, YJ1
Kamei, H1
Goldstein, RH; Kuang, PP; Poliks, C; Rishikof, DC1
Li, Y; Maher, P; Schubert, D1
Back, SA; Gan, X; Li, Y; Rosenberg, PA; Volpe, JJ1
Bannai, S; Ishii, T; Kuriyama-Matsumura, K; Mann, GE; Sato, H; Siow, RC1
Chen, C; Chen, L; Huang, ZZ; Lu, SC; Oh, J; Yang, H; Zeng, Z1
Chen, TS; Song, H1
Aw, TY; Fujimoto, K; Iwakiri, R; Noda, T; Rhoads, CA1
Bannai, S; Itoh, K; Kuriyama-Matsumura, K; Maebara, K; Sasaki, H; Sato, H; Sato, K; Tamba, M; Wang, H; Yamamoto, M1
Hashimoto, K; Iyo, M; Komatsu, N; Shimizu, E1
Anderson, CL; Go, YM; Jones, DP; Kinkade, JM; Kirlin, WG; Ziegler, TR1
Barbacioru, C; Dai, Z; Huang, Y; Sadée, W1
Akaike, A; Izumi, Y; Katsuki, H; Kume, T; Sawada, H; Shimohama, S; Yamamoto, N1
Anderson, CL; Iyer, SS; Jones, DP; Ziegler, TR1
Banjac, A; Bannai, S; Bornkamm, GW; Conrad, M; Daniel, PT; Issels, RD; Kölle, P; Perisic, T; Sato, H; Seiler, A; Tschoep, K; Weiss, N1
Bovee-Oudenhoven, IM; Brummer, RJ; Schonewille, AJ; van Ampting, MT; van der Meer, R; Vink, C1
Castellani, P; Ciriolo, MR; Delfino, L; Lucibello, M; Rubartelli, A; Venè, R1
Bridges, RJ; Patel, SA; Seib, TM1
Fritz, K; Furey, A; Lobner, D; Pauly, K1
Albano, R; Baker, DA; Hjelmhaug, J; Lobner, D; Raddatz, NJ1
Hayashima, K; Katoh, H; Kimura, I1

Other Studies

44 other study(ies) available for cystine and buthionine sulfoximine

ArticleYear
Collateral sensitivity of multidrug-resistant cells to the orphan drug tiopronin.
    Journal of medicinal chemistry, 2011, Jul-28, Volume: 54, Issue:14

    Topics: Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cell Line, Tumor; Doxorubicin; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; HEK293 Cells; Humans; Multidrug Resistance-Associated Proteins; Orphan Drug Production; Paclitaxel; RNA Stability; RNA, Messenger; Structure-Activity Relationship; Tiopronin

2011
Effects of 2-mercaptoethanol and buthionine sulfoximine on cystine metabolism by and proliferation of mitogen-stimulated human and mouse lymphocytes.
    International journal of immunopharmacology, 1992, Volume: 14, Issue:7

    Topics: Adolescent; Adult; Animals; Antimetabolites; Buthionine Sulfoximine; Cystine; Glutathione; Humans; In Vitro Techniques; Lymphocyte Activation; Lymphocytes; Mercaptoethanol; Methionine Sulfoximine; Mice; Mice, Inbred CBA; Protein Biosynthesis; Species Specificity; T-Lymphocytes

1992
Reduction of glutathione is associated with growth restriction and enlargement of bovine pulmonary artery endothelial cells produced by transforming growth factor-beta 1.
    American journal of respiratory cell and molecular biology, 1992, Volume: 6, Issue:4

    Topics: Animals; Buthionine Sulfoximine; Cattle; Cell Division; Cells, Cultured; Cystine; Dose-Response Relationship, Drug; Endothelium, Vascular; Glutathione; Kinetics; Methionine Sulfoximine; Pulmonary Artery; Transforming Growth Factor beta

1992
Protection by cysteine esters against chemically induced pulmonary oedema.
    Biochemical pharmacology, 1991, Dec-11, Volume: 42 Suppl

    Topics: Acetylcysteine; Animals; Buthionine Sulfoximine; Chromatography, High Pressure Liquid; Cysteine; Cystine; DNA; Female; Fluorocarbons; Glutathione; Liver; Lung; Methionine Sulfoximine; Perfusion; Pulmonary Edema; Rats; Sulfhydryl Compounds; Time Factors

1991
Effect of modulators of glutathione synthesis on the hepatotoxicity of 2-methylfuran.
    Biochemical pharmacology, 1991, May-01, Volume: 41, Issue:9

    Topics: Alanine Transaminase; Animals; Antimetabolites; Buthionine Sulfoximine; Chemical and Drug Induced Liver Injury; Cystine; Drug Interactions; Furans; Glutathione; Male; Maleates; Methionine Sulfoximine; Pyrrolidonecarboxylic Acid; Rats; Rats, Inbred Strains; Thiazoles; Thiazolidines

1991
Growth-associated modifications of low-molecular-weight thiols and protein sulfhydryls in human bronchial fibroblasts.
    Journal of cellular physiology, 1990, Volume: 143, Issue:1

    Topics: Bronchi; Buthionine Sulfoximine; Cell Division; Cells, Cultured; Contact Inhibition; Culture Media; Cystine; Fibroblasts; Glutathione; Humans; Methionine Sulfoximine; Oxidation-Reduction; Proteins; Sulfhydryl Compounds

1990
Mercaptoethanol protects glutathione depleted cells.
    Agents and actions, 1987, Volume: 22, Issue:1-2

    Topics: Animals; Buthionine Sulfoximine; Cells, Cultured; Cystine; Glutathione; Leukemia L1210; Mercaptoethanol; Methionine Sulfoximine; Mice; Sulfhydryl Compounds

1987
Origin and turnover of mitochondrial glutathione.
    Proceedings of the National Academy of Sciences of the United States of America, 1985, Volume: 82, Issue:14

    Topics: Animals; Buthionine Sulfoximine; Cystine; Glutamates; Glutathione; Kinetics; Liver; Methionine Sulfoximine; Mitochondria, Liver; Rats; Sulfur Radioisotopes

1985
Buthionine sulfoximine inhibition of cystine uptake and glutathione biosynthesis in human lung carcinoma cells.
    Toxicology and applied pharmacology, 1985, Mar-15, Volume: 77, Issue:3

    Topics: Buthionine Sulfoximine; Cell Line; Cysteine; Cystine; Glutathione; Humans; Lung Neoplasms; Methionine Sulfoximine; Sulfur Radioisotopes

1985
Potentiation of melphalan cytotoxicity in human ovarian cancer cell lines by glutathione depletion.
    Cancer research, 1984, Volume: 44, Issue:11

    Topics: Buthionine Sulfoximine; Cell Line; Cell Survival; Cystine; Drug Resistance; Drug Synergism; Female; Glutathione; Humans; Kinetics; Melphalan; Methionine Sulfoximine; Ovarian Neoplasms

1984
The role of glutathione turnover in the apparent renal secretion of cystine.
    The Journal of biological chemistry, 1981, Dec-10, Volume: 256, Issue:23

    Topics: Amino Acids; Animals; Arginine; Biological Transport; Buthionine Sulfoximine; Cystine; Glutathione; Kidney; Kinetics; Liver; Lysine; Methionine Sulfoximine; Mice

1981
The role of thiols in oxidation of low-density lipoprotein by macrophages.
    Biochemical Society transactions, 1995, Volume: 23, Issue:2

    Topics: Antimetabolites; Buthionine Sulfoximine; Carmustine; Cell Line; Cell-Free System; Cystine; Humans; Kinetics; Lipoproteins, LDL; Macrophages; Methionine Sulfoximine; Oxidation-Reduction; S-Adenosylmethionine; Sulfhydryl Compounds; Thiobarbituric Acid Reactive Substances; Tubercidin

1995
Synthesis of glutathione in the preimplantation mouse embryo.
    Archives of biochemistry and biophysics, 1995, Apr-01, Volume: 318, Issue:1

    Topics: Animals; Antimetabolites; Blastocyst; Buthionine Sulfoximine; Culture Media; Cycloheximide; Cystine; Female; Glutathione; In Vitro Techniques; Maleates; Methionine; Methionine Sulfoximine; Mice; Pregnancy

1995
Human (THP-1) macrophages oxidize LDL by a thiol-dependent mechanism.
    Free radical research, 1994, Volume: 21, Issue:5

    Topics: Buthionine Sulfoximine; Copper; Cysteine; Cystine; Glutathione; Humans; Lipoproteins, LDL; Macrophages; Methionine Sulfoximine; Oxidation-Reduction; Tumor Cells, Cultured

1994
Cystine/glutamate antiporter expression in retinal Müller glial cells: implications for DL-alpha-aminoadipate toxicity.
    Neuroscience, 1993, Volume: 57, Issue:2

    Topics: 2-Aminoadipic Acid; Animals; Antimetabolites; Autoradiography; Buthionine Sulfoximine; Carps; Carrier Proteins; Chlorides; Chromatography, High Pressure Liquid; Cystine; Electroretinography; Glutamates; Glutamic Acid; Glutathione; Isomerism; Methionine Sulfoximine; Neuroglia; Retina; Sodium; Sulfur Radioisotopes

1993
A role for gamma-glutamyl transpeptidase in the transport of cystine into human endothelial cells: relationship to intracellular glutathione.
    Biochimica et biophysica acta, 1994, Jul-21, Volume: 1222, Issue:3

    Topics: Amino Acid Transport Systems; Amino Acids; Biological Transport; Buthionine Sulfoximine; Carrier Proteins; Cells, Cultured; Cystine; Endothelium, Vascular; gamma-Glutamyltransferase; Glutamates; Glutathione; Humans; Isoxazoles; Methionine Sulfoximine

1994
Modifications of cellular thiols during growth and squamous differentiation of cultured human bronchial epithelial cells.
    Experimental cell research, 1994, Volume: 211, Issue:1

    Topics: Antimetabolites; Bronchi; Buthionine Sulfoximine; Calcium; Cell Differentiation; Cell Division; Cells, Cultured; Cysteine; Cystine; Epithelial Cells; Epithelium; Glutathione; Humans; Maleates; Methionine Sulfoximine; Oxidation-Reduction; Serum Albumin, Bovine; Sulfhydryl Compounds; Transforming Growth Factor beta

1994
Exogenous glutathione attenuates the antiproliferative effect of buthionine sulfoximine.
    Toxicology, 1994, Mar-11, Volume: 88, Issue:1-3

    Topics: Antimetabolites, Antineoplastic; Buthionine Sulfoximine; Carcinoma; Cell Division; Cystine; Glutathione; Humans; Lung Neoplasms; Methionine Sulfoximine; Tumor Cells, Cultured

1994
Human (THP-1) macrophages oxidize LDL by a thiol-dependent mechanism.
    Free radical research, 1996, Volume: 25, Issue:2

    Topics: Buthionine Sulfoximine; Copper; Cysteine; Cystine; Glutathione; Humans; Kinetics; Lipoproteins, LDL; Macrophages; Oxidation-Reduction; Tumor Cells, Cultured

1996
Transforming growth factor B1 decreases uptake of glutathione precursor amino acids in bovine pulmonary artery endothelial cells.
    Endothelium : journal of endothelial cell research, 1997, Volume: 5, Issue:1

    Topics: Animals; Biological Transport; Buthionine Sulfoximine; Cattle; Cell Count; Cells, Cultured; Cystine; Endothelium, Vascular; Enzyme Inhibitors; gamma-Glutamyltransferase; Glutamate-Cysteine Ligase; Glutamic Acid; Glutathione; Isoxazoles; Pulmonary Artery; Transforming Growth Factor beta

1997
Role of glutathione metabolism in the glutamate-induced programmed cell death of neuronal-like PC12 cells.
    European journal of pharmacology, 1997, May-12, Volume: 326, Issue:1

    Topics: Acetylcysteine; Animals; Antimetabolites, Antineoplastic; Apoptosis; Buthionine Sulfoximine; Culture Media, Serum-Free; Cycloheximide; Cystine; Glutamic Acid; Glutathione; L-Lactate Dehydrogenase; Neurons; Oxidative Stress; PC12 Cells; Protein Synthesis Inhibitors; Rats

1997
Opposite regulation of tyrosinase and glutathione peroxidase by intracellular thiols in human melanoma cells.
    Archives of dermatological research, 1997, Volume: 289, Issue:6

    Topics: Buthionine Sulfoximine; Carmustine; Cysteine; Cystine; Glutathione; Glutathione Peroxidase; Humans; Melanins; Melanoma; Monophenol Monooxygenase; Oxidative Stress; Sodium Selenite; Sulfhydryl Compounds; Tumor Cells, Cultured

1997
Increased cystine uptake capability associated with malignant progression of Nb2 lymphoma cells.
    Leukemia, 1997, Volume: 11, Issue:8

    Topics: Animals; Biological Transport; Buthionine Sulfoximine; Cystine; Enzyme Inhibitors; Glutamate-Cysteine Ligase; Glutamates; Glutathione; Humans; Lymphoma, T-Cell; Mercaptoethanol; Rats; Tumor Cells, Cultured

1997
Cystine starvation induces reversible large-body formation from nuclear bodies in T24 cells.
    Experimental cell research, 1997, Nov-25, Volume: 237, Issue:1

    Topics: Amino Acids; Antigens, Nuclear; Autoantigens; Buthionine Sulfoximine; Cell Nucleus; Cystine; Humans; Microscopy, Electron; Microscopy, Immunoelectron; Neoplasm Proteins; Nuclear Proteins; Promyelocytic Leukemia Protein; Sulfhydryl Reagents; Transcription Factors; Tumor Cells, Cultured; Tumor Suppressor Proteins; Urinary Bladder Neoplasms

1997
Regulation of type I collagen mRNA in lung fibroblasts by cystine availability.
    The Biochemical journal, 1998, Apr-15, Volume: 331 ( Pt 2)

    Topics: Amino Acids, Branched-Chain; Buthionine Sulfoximine; Cells, Cultured; Collagen; Culture Media; Cystine; Drug Stability; Embryo, Mammalian; Enzyme Inhibitors; Fibroblasts; Gene Expression Regulation; Glutamate-Cysteine Ligase; Glutamine; Glutathione; Humans; Lung; Methionine; Oxidation-Reduction; RNA, Messenger

1998
Phosphatidylcholine-specific phospholipase C regulates glutamate-induced nerve cell death.
    Proceedings of the National Academy of Sciences of the United States of America, 1998, Jun-23, Volume: 95, Issue:13

    Topics: Animals; Antimetabolites; Apoptosis; Bridged-Ring Compounds; Buthionine Sulfoximine; Cell Line; Cystine; Glutamic Acid; Hippocampus; Mice; Neurons; Norbornanes; Phosphodiesterase Inhibitors; Thiocarbamates; Thiones; Type C Phospholipases

1998
Maturation-dependent vulnerability of oligodendrocytes to oxidative stress-induced death caused by glutathione depletion.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 1998, Aug-15, Volume: 18, Issue:16

    Topics: Animals; Buthionine Sulfoximine; Cell Count; Cell Death; Cell Division; Cells, Cultured; Cellular Senescence; Cystine; Free Radical Scavengers; Free Radicals; Glutathione; Growth Substances; Oligodendroglia; Oxidative Stress; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Stem Cells

1998
Induction of cystine transport via system x-c and maintenance of intracellular glutathione levels in pancreatic acinar and islet cell lines.
    Biochimica et biophysica acta, 1998, Nov-11, Volume: 1414, Issue:1-2

    Topics: Amino Acid Transport Systems, Basic; Amino Acid Transport Systems, Neutral; Animals; Biological Transport; Buthionine Sulfoximine; Carrier Proteins; Cell Line; Cystine; Glutathione; Homocysteine; Islets of Langerhans; Maleates; Mercaptoethanol; Mice; Rats; Time Factors

1998
Mechanism and significance of increased glutathione level in human hepatocellular carcinoma and liver regeneration.
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2001, Volume: 15, Issue:1

    Topics: Antioxidants; Buthionine Sulfoximine; Carcinoma, Hepatocellular; Cell Division; Cystine; DNA; Glutamate-Cysteine Ligase; Glutathione; Glutathione Synthase; Hepatectomy; Humans; Liver; Liver Regeneration; NF-kappa B; Promoter Regions, Genetic; Protein Binding; Protein Subunits; Response Elements; RNA, Messenger; Transcription Factor AP-1; Tumor Cells, Cultured

2001
p-Aminophenol-induced liver toxicity: tentative evidence of a role for acetaminophen.
    Journal of biochemical and molecular toxicology, 2001, Volume: 15, Issue:1

    Topics: Acetaminophen; Acetylation; Alanine Transaminase; Aminophenols; Animals; Ascorbic Acid; Buthionine Sulfoximine; Chemical and Drug Induced Liver Injury; Chromatography, High Pressure Liquid; Cysteine; Cystine; Dose-Response Relationship, Drug; Drug Synergism; Glutathione; Glutathione Disulfide; L-Iditol 2-Dehydrogenase; Liver; Male; Mice; Mice, Inbred C57BL

2001
Exogenous cysteine and cystine promote cell proliferation in CaCo-2 cells.
    Cell proliferation, 2002, Volume: 35, Issue:2

    Topics: Antimetabolites; Blotting, Western; Buthionine Sulfoximine; Caco-2 Cells; Chromatography, High Pressure Liquid; Cyclin D1; Cysteine; Cystine; Flow Cytometry; G1 Phase; Glutathione; Glutathione Disulfide; Humans; Phosphorylation; Retinoblastoma Protein; S Phase

2002
Electrophile response element-mediated induction of the cystine/glutamate exchange transporter gene expression.
    The Journal of biological chemistry, 2002, Nov-22, Volume: 277, Issue:47

    Topics: 5' Flanking Region; Amino Acid Transport System y+; Animals; Base Sequence; Buthionine Sulfoximine; Carrier Proteins; Cell Line; Cricetinae; Cysteine; Cystine; DNA-Binding Proteins; Enzyme Inhibitors; Fibroblasts; Fusion Regulatory Protein 1, Heavy Chain; Gene Expression Regulation; Genes, Reporter; Glutathione; Humans; Maleates; Mice; Mutation; NF-E2-Related Factor 2; Recombinant Fusion Proteins; Response Elements; Sequence Analysis, DNA; Trans-Activators

2002
Roles of endogenous glutathione levels on 6-hydroxydopamine-induced apoptotic neuronal cell death in human neuroblastoma SK-N-SH cells.
    Neuropharmacology, 2002, Volume: 43, Issue:3

    Topics: Acetylcysteine; Apoptosis; Benzimidazoles; Brain Neoplasms; Buthionine Sulfoximine; Cystine; DNA Fragmentation; Fluorescent Dyes; Free Radical Scavengers; Glutathione; Humans; Neuroblastoma; Neurons; Oxidopamine; Sympatholytics; Tumor Cells, Cultured

2002
Cysteine/cystine couple is a newly recognized node in the circuitry for biologic redox signaling and control.
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2004, Volume: 18, Issue:11

    Topics: Buthionine Sulfoximine; Chromatography, High Pressure Liquid; Colon; Culture Media; Cysteine; Cystine; Cytosol; Digitonin; Disulfides; Enzyme Inhibitors; Epithelial Cells; Glutamate-Cysteine Ligase; Glutathione; Humans; Isothiocyanates; Models, Biological; Oxidation-Reduction; Sulfhydryl Compounds; Thioredoxins

2004
Cystine-glutamate transporter SLC7A11 in cancer chemosensitivity and chemoresistance.
    Cancer research, 2005, Aug-15, Volume: 65, Issue:16

    Topics: Amino Acid Transport System y+; Antimetabolites, Antineoplastic; Buthionine Sulfoximine; Cell Line, Tumor; Cystine; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Glutathione; Humans; Neoplasms; RNA, Small Interfering

2005
Iron accelerates the conversion of dopamine-oxidized intermediates into melanin and provides protection in SH-SY5Y cells.
    Journal of neuroscience research, 2005, Oct-01, Volume: 82, Issue:1

    Topics: Acetylcysteine; Analysis of Variance; Area Under Curve; Buthionine Sulfoximine; Catalase; Cell Death; Cell Line, Tumor; Cell Survival; Chromatography, High Pressure Liquid; Cystine; Dopamine; Dose-Response Relationship, Drug; Drug Interactions; Electrochemistry; Enzyme Inhibitors; Humans; Hydrogen Peroxide; Indolequinones; Iron; Melanins; Models, Biological; Neuroblastoma; Superoxide Dismutase; Tetrazolium Salts; Thiazoles; Time Factors

2005
Control of extracellular cysteine/cystine redox state by HT-29 cells is independent of cellular glutathione.
    American journal of physiology. Regulatory, integrative and comparative physiology, 2007, Volume: 293, Issue:3

    Topics: Biological Transport, Active; Buthionine Sulfoximine; Culture Media; Cysteine; Cystine; Disulfides; Extracellular Space; Glutathione; HT29 Cells; Humans; Kinetics; Oxidation-Reduction; Oxidative Stress; Sulfhydryl Compounds

2007
The cystine/cysteine cycle: a redox cycle regulating susceptibility versus resistance to cell death.
    Oncogene, 2008, Mar-06, Volume: 27, Issue:11

    Topics: Amino Acid Transport System y+; Animals; Antimetabolites, Antineoplastic; Apoptosis; Blotting, Northern; Buthionine Sulfoximine; Caspases; Cell Survival; Cysteine; Cystine; Fluorescent Antibody Technique; Glutamic Acid; Glutathione; Humans; Hydrogen Peroxide; Immunoblotting; Lipid Peroxidation; Membrane Potential, Mitochondrial; Mice; Oxidants; Oxidation-Reduction; Oxidative Stress; Reactive Oxygen Species

2008
Intestinal barrier function in response to abundant or depleted mucosal glutathione in Salmonella-infected rats.
    BMC physiology, 2009, Apr-17, Volume: 9

    Topics: Animals; Bacterial Translocation; Buthionine Sulfoximine; Cystine; Diarrhea; Disease Susceptibility; Glutathione; Ileitis; Interleukin-1beta; Intestinal Mucosa; Lipopolysaccharides; Liver; Male; Nitric Oxide; Oxidative Stress; Peroxidase; Rats; Rats, Wistar; Salmonella enteritidis; Salmonella Infections, Animal; Specific Pathogen-Free Organisms

2009
The cystine/cysteine cycle and GSH are independent and crucial antioxidant systems in malignant melanoma cells and represent druggable targets.
    Antioxidants & redox signaling, 2011, Nov-01, Volume: 15, Issue:9

    Topics: Antioxidants; Arsenic Trioxide; Arsenicals; Blotting, Western; Buthionine Sulfoximine; Cell Survival; Cysteine; Cystine; Glutathione; Glycine; HMGB1 Protein; Humans; Immunohistochemistry; Melanoma; Oxidation-Reduction; Oxides; Reactive Oxygen Species; Real-Time Polymerase Chain Reaction; Tumor Cells, Cultured

2011
Regulation of the system x(C)- cystine/glutamate exchanger by intracellular glutathione levels in rat astrocyte primary cultures.
    Glia, 2011, Volume: 59, Issue:10

    Topics: Amino Acid Transport Systems; Analysis of Variance; Animals; Animals, Newborn; Antimetabolites; Astrocytes; Buthionine Sulfoximine; Cells, Cultured; Cerebral Cortex; Cyclic CMP; Cystine; Glutamic Acid; Glutathione; NF-E2-Related Factor 2; Rats; Reactive Oxygen Species; RNA, Messenger; Tritium

2011
Insulin-like growth factor 1 and transforming growth factor-β stimulate cystine/glutamate exchange activity in dental pulp cells.
    Journal of endodontics, 2011, Volume: 37, Issue:7

    Topics: Amino Acid Transport System y+; Antimetabolites; Antioxidants; Buthionine Sulfoximine; Cells, Cultured; Composite Resins; Cystine; Dental Pulp; Glutamic Acid; Glutathione; Humans; Insulin-Like Growth Factor I; Pulp Capping and Pulpectomy Agents; Transforming Growth Factor beta

2011
Regulation of System xc(-) by Pharmacological Manipulation of Cellular Thiols.
    Oxidative medicine and cellular longevity, 2015, Volume: 2015

    Topics: Amino Acid Transport System y+; Animals; Buthionine Sulfoximine; Carbon Isotopes; Cystine; Female; Glutathione; Maleates; Mice; Neurotoxins; Oxidative Stress; Sulfhydryl Compounds

2015
Role of ferritinophagy in cystine deprivation-induced cell death in glioblastoma cells.
    Biochemical and biophysical research communications, 2021, 02-05, Volume: 539

    Topics: Antimetabolites, Antineoplastic; Autophagy; Brain Neoplasms; Buthionine Sulfoximine; Cell Death; Cell Line, Tumor; Cystine; Ferritins; Ferroptosis; Glioblastoma; Glutathione; Humans; Iron; Lipid Peroxidation; Oxidoreductases

2021