cystine has been researched along with buthionine sulfoximine in 44 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 5 (11.36) | 18.7374 |
1990's | 22 (50.00) | 18.2507 |
2000's | 11 (25.00) | 29.6817 |
2010's | 5 (11.36) | 24.3611 |
2020's | 1 (2.27) | 2.80 |
Authors | Studies |
---|---|
Brimacombe, KR; Dulcey, AE; Goldsborough, AS; Gottesman, MM; Griffiths, G; Hall, MD; Handley, MD; Kannan, P; Pluchino, KM | 1 |
Lawrence, DA; Messina, JP | 1 |
Das, SK; Fanburg, BL; White, AC | 1 |
Hill, L; Lailey, AF; Lawston, IW; Stanton, D; Upshall, DG | 1 |
Boyd, MR; Ravindranath, V | 1 |
Atzori, L; Cotgreave, I; Dypbukt, JM; Edman, CC; Grafström, RC; Moldéus, P; Sundqvist, K | 1 |
Broome, JD; Chen, PC; Gaetjens, E | 1 |
Griffith, OW; Meister, A | 1 |
Brodie, AE; Reed, DJ | 1 |
Green, JA; Hamilton, TC; Ozols, RF; Rogan, AM; Vistica, DT; Young, RC | 1 |
Griffith, OW | 1 |
Graham, A; Wood, JL | 1 |
Gardiner, CS; Reed, DJ | 1 |
Graham, A; O'Leary, VJ; Stone, D; Wood, JL | 2 |
Ishita, S; Kato, S; Mawatari, K; Sugawara, K | 1 |
Cotgreave, IA; Schuppe-Koistinen, I | 1 |
Atzori, L; Dypbukt, JM; Grafström, RC; Hybbinette, SS; Moldéus, P | 1 |
Kang, YJ | 1 |
Boustani, MR; Fanburg, BL; Hertig, IA; Maloney, EK; White, AC | 1 |
Duval, D; Froissard, P; Monrocq, H | 1 |
Benathan, M | 1 |
Bruchovsky, N; Buckley, AR; Buckley, DJ; Gout, PW; Kang, YJ | 1 |
Kamei, H | 1 |
Goldstein, RH; Kuang, PP; Poliks, C; Rishikof, DC | 1 |
Li, Y; Maher, P; Schubert, D | 1 |
Back, SA; Gan, X; Li, Y; Rosenberg, PA; Volpe, JJ | 1 |
Bannai, S; Ishii, T; Kuriyama-Matsumura, K; Mann, GE; Sato, H; Siow, RC | 1 |
Chen, C; Chen, L; Huang, ZZ; Lu, SC; Oh, J; Yang, H; Zeng, Z | 1 |
Chen, TS; Song, H | 1 |
Aw, TY; Fujimoto, K; Iwakiri, R; Noda, T; Rhoads, CA | 1 |
Bannai, S; Itoh, K; Kuriyama-Matsumura, K; Maebara, K; Sasaki, H; Sato, H; Sato, K; Tamba, M; Wang, H; Yamamoto, M | 1 |
Hashimoto, K; Iyo, M; Komatsu, N; Shimizu, E | 1 |
Anderson, CL; Go, YM; Jones, DP; Kinkade, JM; Kirlin, WG; Ziegler, TR | 1 |
Barbacioru, C; Dai, Z; Huang, Y; Sadée, W | 1 |
Akaike, A; Izumi, Y; Katsuki, H; Kume, T; Sawada, H; Shimohama, S; Yamamoto, N | 1 |
Anderson, CL; Iyer, SS; Jones, DP; Ziegler, TR | 1 |
Banjac, A; Bannai, S; Bornkamm, GW; Conrad, M; Daniel, PT; Issels, RD; Kölle, P; Perisic, T; Sato, H; Seiler, A; Tschoep, K; Weiss, N | 1 |
Bovee-Oudenhoven, IM; Brummer, RJ; Schonewille, AJ; van Ampting, MT; van der Meer, R; Vink, C | 1 |
Castellani, P; Ciriolo, MR; Delfino, L; Lucibello, M; Rubartelli, A; Venè, R | 1 |
Bridges, RJ; Patel, SA; Seib, TM | 1 |
Fritz, K; Furey, A; Lobner, D; Pauly, K | 1 |
Albano, R; Baker, DA; Hjelmhaug, J; Lobner, D; Raddatz, NJ | 1 |
Hayashima, K; Katoh, H; Kimura, I | 1 |
44 other study(ies) available for cystine and buthionine sulfoximine
Article | Year |
---|---|
Collateral sensitivity of multidrug-resistant cells to the orphan drug tiopronin.
Topics: Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cell Line, Tumor; Doxorubicin; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; HEK293 Cells; Humans; Multidrug Resistance-Associated Proteins; Orphan Drug Production; Paclitaxel; RNA Stability; RNA, Messenger; Structure-Activity Relationship; Tiopronin | 2011 |
Effects of 2-mercaptoethanol and buthionine sulfoximine on cystine metabolism by and proliferation of mitogen-stimulated human and mouse lymphocytes.
Topics: Adolescent; Adult; Animals; Antimetabolites; Buthionine Sulfoximine; Cystine; Glutathione; Humans; In Vitro Techniques; Lymphocyte Activation; Lymphocytes; Mercaptoethanol; Methionine Sulfoximine; Mice; Mice, Inbred CBA; Protein Biosynthesis; Species Specificity; T-Lymphocytes | 1992 |
Reduction of glutathione is associated with growth restriction and enlargement of bovine pulmonary artery endothelial cells produced by transforming growth factor-beta 1.
Topics: Animals; Buthionine Sulfoximine; Cattle; Cell Division; Cells, Cultured; Cystine; Dose-Response Relationship, Drug; Endothelium, Vascular; Glutathione; Kinetics; Methionine Sulfoximine; Pulmonary Artery; Transforming Growth Factor beta | 1992 |
Protection by cysteine esters against chemically induced pulmonary oedema.
Topics: Acetylcysteine; Animals; Buthionine Sulfoximine; Chromatography, High Pressure Liquid; Cysteine; Cystine; DNA; Female; Fluorocarbons; Glutathione; Liver; Lung; Methionine Sulfoximine; Perfusion; Pulmonary Edema; Rats; Sulfhydryl Compounds; Time Factors | 1991 |
Effect of modulators of glutathione synthesis on the hepatotoxicity of 2-methylfuran.
Topics: Alanine Transaminase; Animals; Antimetabolites; Buthionine Sulfoximine; Chemical and Drug Induced Liver Injury; Cystine; Drug Interactions; Furans; Glutathione; Male; Maleates; Methionine Sulfoximine; Pyrrolidonecarboxylic Acid; Rats; Rats, Inbred Strains; Thiazoles; Thiazolidines | 1991 |
Growth-associated modifications of low-molecular-weight thiols and protein sulfhydryls in human bronchial fibroblasts.
Topics: Bronchi; Buthionine Sulfoximine; Cell Division; Cells, Cultured; Contact Inhibition; Culture Media; Cystine; Fibroblasts; Glutathione; Humans; Methionine Sulfoximine; Oxidation-Reduction; Proteins; Sulfhydryl Compounds | 1990 |
Mercaptoethanol protects glutathione depleted cells.
Topics: Animals; Buthionine Sulfoximine; Cells, Cultured; Cystine; Glutathione; Leukemia L1210; Mercaptoethanol; Methionine Sulfoximine; Mice; Sulfhydryl Compounds | 1987 |
Origin and turnover of mitochondrial glutathione.
Topics: Animals; Buthionine Sulfoximine; Cystine; Glutamates; Glutathione; Kinetics; Liver; Methionine Sulfoximine; Mitochondria, Liver; Rats; Sulfur Radioisotopes | 1985 |
Buthionine sulfoximine inhibition of cystine uptake and glutathione biosynthesis in human lung carcinoma cells.
Topics: Buthionine Sulfoximine; Cell Line; Cysteine; Cystine; Glutathione; Humans; Lung Neoplasms; Methionine Sulfoximine; Sulfur Radioisotopes | 1985 |
Potentiation of melphalan cytotoxicity in human ovarian cancer cell lines by glutathione depletion.
Topics: Buthionine Sulfoximine; Cell Line; Cell Survival; Cystine; Drug Resistance; Drug Synergism; Female; Glutathione; Humans; Kinetics; Melphalan; Methionine Sulfoximine; Ovarian Neoplasms | 1984 |
The role of glutathione turnover in the apparent renal secretion of cystine.
Topics: Amino Acids; Animals; Arginine; Biological Transport; Buthionine Sulfoximine; Cystine; Glutathione; Kidney; Kinetics; Liver; Lysine; Methionine Sulfoximine; Mice | 1981 |
The role of thiols in oxidation of low-density lipoprotein by macrophages.
Topics: Antimetabolites; Buthionine Sulfoximine; Carmustine; Cell Line; Cell-Free System; Cystine; Humans; Kinetics; Lipoproteins, LDL; Macrophages; Methionine Sulfoximine; Oxidation-Reduction; S-Adenosylmethionine; Sulfhydryl Compounds; Thiobarbituric Acid Reactive Substances; Tubercidin | 1995 |
Synthesis of glutathione in the preimplantation mouse embryo.
Topics: Animals; Antimetabolites; Blastocyst; Buthionine Sulfoximine; Culture Media; Cycloheximide; Cystine; Female; Glutathione; In Vitro Techniques; Maleates; Methionine; Methionine Sulfoximine; Mice; Pregnancy | 1995 |
Human (THP-1) macrophages oxidize LDL by a thiol-dependent mechanism.
Topics: Buthionine Sulfoximine; Copper; Cysteine; Cystine; Glutathione; Humans; Lipoproteins, LDL; Macrophages; Methionine Sulfoximine; Oxidation-Reduction; Tumor Cells, Cultured | 1994 |
Cystine/glutamate antiporter expression in retinal Müller glial cells: implications for DL-alpha-aminoadipate toxicity.
Topics: 2-Aminoadipic Acid; Animals; Antimetabolites; Autoradiography; Buthionine Sulfoximine; Carps; Carrier Proteins; Chlorides; Chromatography, High Pressure Liquid; Cystine; Electroretinography; Glutamates; Glutamic Acid; Glutathione; Isomerism; Methionine Sulfoximine; Neuroglia; Retina; Sodium; Sulfur Radioisotopes | 1993 |
A role for gamma-glutamyl transpeptidase in the transport of cystine into human endothelial cells: relationship to intracellular glutathione.
Topics: Amino Acid Transport Systems; Amino Acids; Biological Transport; Buthionine Sulfoximine; Carrier Proteins; Cells, Cultured; Cystine; Endothelium, Vascular; gamma-Glutamyltransferase; Glutamates; Glutathione; Humans; Isoxazoles; Methionine Sulfoximine | 1994 |
Modifications of cellular thiols during growth and squamous differentiation of cultured human bronchial epithelial cells.
Topics: Antimetabolites; Bronchi; Buthionine Sulfoximine; Calcium; Cell Differentiation; Cell Division; Cells, Cultured; Cysteine; Cystine; Epithelial Cells; Epithelium; Glutathione; Humans; Maleates; Methionine Sulfoximine; Oxidation-Reduction; Serum Albumin, Bovine; Sulfhydryl Compounds; Transforming Growth Factor beta | 1994 |
Exogenous glutathione attenuates the antiproliferative effect of buthionine sulfoximine.
Topics: Antimetabolites, Antineoplastic; Buthionine Sulfoximine; Carcinoma; Cell Division; Cystine; Glutathione; Humans; Lung Neoplasms; Methionine Sulfoximine; Tumor Cells, Cultured | 1994 |
Human (THP-1) macrophages oxidize LDL by a thiol-dependent mechanism.
Topics: Buthionine Sulfoximine; Copper; Cysteine; Cystine; Glutathione; Humans; Kinetics; Lipoproteins, LDL; Macrophages; Oxidation-Reduction; Tumor Cells, Cultured | 1996 |
Transforming growth factor B1 decreases uptake of glutathione precursor amino acids in bovine pulmonary artery endothelial cells.
Topics: Animals; Biological Transport; Buthionine Sulfoximine; Cattle; Cell Count; Cells, Cultured; Cystine; Endothelium, Vascular; Enzyme Inhibitors; gamma-Glutamyltransferase; Glutamate-Cysteine Ligase; Glutamic Acid; Glutathione; Isoxazoles; Pulmonary Artery; Transforming Growth Factor beta | 1997 |
Role of glutathione metabolism in the glutamate-induced programmed cell death of neuronal-like PC12 cells.
Topics: Acetylcysteine; Animals; Antimetabolites, Antineoplastic; Apoptosis; Buthionine Sulfoximine; Culture Media, Serum-Free; Cycloheximide; Cystine; Glutamic Acid; Glutathione; L-Lactate Dehydrogenase; Neurons; Oxidative Stress; PC12 Cells; Protein Synthesis Inhibitors; Rats | 1997 |
Opposite regulation of tyrosinase and glutathione peroxidase by intracellular thiols in human melanoma cells.
Topics: Buthionine Sulfoximine; Carmustine; Cysteine; Cystine; Glutathione; Glutathione Peroxidase; Humans; Melanins; Melanoma; Monophenol Monooxygenase; Oxidative Stress; Sodium Selenite; Sulfhydryl Compounds; Tumor Cells, Cultured | 1997 |
Increased cystine uptake capability associated with malignant progression of Nb2 lymphoma cells.
Topics: Animals; Biological Transport; Buthionine Sulfoximine; Cystine; Enzyme Inhibitors; Glutamate-Cysteine Ligase; Glutamates; Glutathione; Humans; Lymphoma, T-Cell; Mercaptoethanol; Rats; Tumor Cells, Cultured | 1997 |
Cystine starvation induces reversible large-body formation from nuclear bodies in T24 cells.
Topics: Amino Acids; Antigens, Nuclear; Autoantigens; Buthionine Sulfoximine; Cell Nucleus; Cystine; Humans; Microscopy, Electron; Microscopy, Immunoelectron; Neoplasm Proteins; Nuclear Proteins; Promyelocytic Leukemia Protein; Sulfhydryl Reagents; Transcription Factors; Tumor Cells, Cultured; Tumor Suppressor Proteins; Urinary Bladder Neoplasms | 1997 |
Regulation of type I collagen mRNA in lung fibroblasts by cystine availability.
Topics: Amino Acids, Branched-Chain; Buthionine Sulfoximine; Cells, Cultured; Collagen; Culture Media; Cystine; Drug Stability; Embryo, Mammalian; Enzyme Inhibitors; Fibroblasts; Gene Expression Regulation; Glutamate-Cysteine Ligase; Glutamine; Glutathione; Humans; Lung; Methionine; Oxidation-Reduction; RNA, Messenger | 1998 |
Phosphatidylcholine-specific phospholipase C regulates glutamate-induced nerve cell death.
Topics: Animals; Antimetabolites; Apoptosis; Bridged-Ring Compounds; Buthionine Sulfoximine; Cell Line; Cystine; Glutamic Acid; Hippocampus; Mice; Neurons; Norbornanes; Phosphodiesterase Inhibitors; Thiocarbamates; Thiones; Type C Phospholipases | 1998 |
Maturation-dependent vulnerability of oligodendrocytes to oxidative stress-induced death caused by glutathione depletion.
Topics: Animals; Buthionine Sulfoximine; Cell Count; Cell Death; Cell Division; Cells, Cultured; Cellular Senescence; Cystine; Free Radical Scavengers; Free Radicals; Glutathione; Growth Substances; Oligodendroglia; Oxidative Stress; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Stem Cells | 1998 |
Induction of cystine transport via system x-c and maintenance of intracellular glutathione levels in pancreatic acinar and islet cell lines.
Topics: Amino Acid Transport Systems, Basic; Amino Acid Transport Systems, Neutral; Animals; Biological Transport; Buthionine Sulfoximine; Carrier Proteins; Cell Line; Cystine; Glutathione; Homocysteine; Islets of Langerhans; Maleates; Mercaptoethanol; Mice; Rats; Time Factors | 1998 |
Mechanism and significance of increased glutathione level in human hepatocellular carcinoma and liver regeneration.
Topics: Antioxidants; Buthionine Sulfoximine; Carcinoma, Hepatocellular; Cell Division; Cystine; DNA; Glutamate-Cysteine Ligase; Glutathione; Glutathione Synthase; Hepatectomy; Humans; Liver; Liver Regeneration; NF-kappa B; Promoter Regions, Genetic; Protein Binding; Protein Subunits; Response Elements; RNA, Messenger; Transcription Factor AP-1; Tumor Cells, Cultured | 2001 |
p-Aminophenol-induced liver toxicity: tentative evidence of a role for acetaminophen.
Topics: Acetaminophen; Acetylation; Alanine Transaminase; Aminophenols; Animals; Ascorbic Acid; Buthionine Sulfoximine; Chemical and Drug Induced Liver Injury; Chromatography, High Pressure Liquid; Cysteine; Cystine; Dose-Response Relationship, Drug; Drug Synergism; Glutathione; Glutathione Disulfide; L-Iditol 2-Dehydrogenase; Liver; Male; Mice; Mice, Inbred C57BL | 2001 |
Exogenous cysteine and cystine promote cell proliferation in CaCo-2 cells.
Topics: Antimetabolites; Blotting, Western; Buthionine Sulfoximine; Caco-2 Cells; Chromatography, High Pressure Liquid; Cyclin D1; Cysteine; Cystine; Flow Cytometry; G1 Phase; Glutathione; Glutathione Disulfide; Humans; Phosphorylation; Retinoblastoma Protein; S Phase | 2002 |
Electrophile response element-mediated induction of the cystine/glutamate exchange transporter gene expression.
Topics: 5' Flanking Region; Amino Acid Transport System y+; Animals; Base Sequence; Buthionine Sulfoximine; Carrier Proteins; Cell Line; Cricetinae; Cysteine; Cystine; DNA-Binding Proteins; Enzyme Inhibitors; Fibroblasts; Fusion Regulatory Protein 1, Heavy Chain; Gene Expression Regulation; Genes, Reporter; Glutathione; Humans; Maleates; Mice; Mutation; NF-E2-Related Factor 2; Recombinant Fusion Proteins; Response Elements; Sequence Analysis, DNA; Trans-Activators | 2002 |
Roles of endogenous glutathione levels on 6-hydroxydopamine-induced apoptotic neuronal cell death in human neuroblastoma SK-N-SH cells.
Topics: Acetylcysteine; Apoptosis; Benzimidazoles; Brain Neoplasms; Buthionine Sulfoximine; Cystine; DNA Fragmentation; Fluorescent Dyes; Free Radical Scavengers; Glutathione; Humans; Neuroblastoma; Neurons; Oxidopamine; Sympatholytics; Tumor Cells, Cultured | 2002 |
Cysteine/cystine couple is a newly recognized node in the circuitry for biologic redox signaling and control.
Topics: Buthionine Sulfoximine; Chromatography, High Pressure Liquid; Colon; Culture Media; Cysteine; Cystine; Cytosol; Digitonin; Disulfides; Enzyme Inhibitors; Epithelial Cells; Glutamate-Cysteine Ligase; Glutathione; Humans; Isothiocyanates; Models, Biological; Oxidation-Reduction; Sulfhydryl Compounds; Thioredoxins | 2004 |
Cystine-glutamate transporter SLC7A11 in cancer chemosensitivity and chemoresistance.
Topics: Amino Acid Transport System y+; Antimetabolites, Antineoplastic; Buthionine Sulfoximine; Cell Line, Tumor; Cystine; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Glutathione; Humans; Neoplasms; RNA, Small Interfering | 2005 |
Iron accelerates the conversion of dopamine-oxidized intermediates into melanin and provides protection in SH-SY5Y cells.
Topics: Acetylcysteine; Analysis of Variance; Area Under Curve; Buthionine Sulfoximine; Catalase; Cell Death; Cell Line, Tumor; Cell Survival; Chromatography, High Pressure Liquid; Cystine; Dopamine; Dose-Response Relationship, Drug; Drug Interactions; Electrochemistry; Enzyme Inhibitors; Humans; Hydrogen Peroxide; Indolequinones; Iron; Melanins; Models, Biological; Neuroblastoma; Superoxide Dismutase; Tetrazolium Salts; Thiazoles; Time Factors | 2005 |
Control of extracellular cysteine/cystine redox state by HT-29 cells is independent of cellular glutathione.
Topics: Biological Transport, Active; Buthionine Sulfoximine; Culture Media; Cysteine; Cystine; Disulfides; Extracellular Space; Glutathione; HT29 Cells; Humans; Kinetics; Oxidation-Reduction; Oxidative Stress; Sulfhydryl Compounds | 2007 |
The cystine/cysteine cycle: a redox cycle regulating susceptibility versus resistance to cell death.
Topics: Amino Acid Transport System y+; Animals; Antimetabolites, Antineoplastic; Apoptosis; Blotting, Northern; Buthionine Sulfoximine; Caspases; Cell Survival; Cysteine; Cystine; Fluorescent Antibody Technique; Glutamic Acid; Glutathione; Humans; Hydrogen Peroxide; Immunoblotting; Lipid Peroxidation; Membrane Potential, Mitochondrial; Mice; Oxidants; Oxidation-Reduction; Oxidative Stress; Reactive Oxygen Species | 2008 |
Intestinal barrier function in response to abundant or depleted mucosal glutathione in Salmonella-infected rats.
Topics: Animals; Bacterial Translocation; Buthionine Sulfoximine; Cystine; Diarrhea; Disease Susceptibility; Glutathione; Ileitis; Interleukin-1beta; Intestinal Mucosa; Lipopolysaccharides; Liver; Male; Nitric Oxide; Oxidative Stress; Peroxidase; Rats; Rats, Wistar; Salmonella enteritidis; Salmonella Infections, Animal; Specific Pathogen-Free Organisms | 2009 |
The cystine/cysteine cycle and GSH are independent and crucial antioxidant systems in malignant melanoma cells and represent druggable targets.
Topics: Antioxidants; Arsenic Trioxide; Arsenicals; Blotting, Western; Buthionine Sulfoximine; Cell Survival; Cysteine; Cystine; Glutathione; Glycine; HMGB1 Protein; Humans; Immunohistochemistry; Melanoma; Oxidation-Reduction; Oxides; Reactive Oxygen Species; Real-Time Polymerase Chain Reaction; Tumor Cells, Cultured | 2011 |
Regulation of the system x(C)- cystine/glutamate exchanger by intracellular glutathione levels in rat astrocyte primary cultures.
Topics: Amino Acid Transport Systems; Analysis of Variance; Animals; Animals, Newborn; Antimetabolites; Astrocytes; Buthionine Sulfoximine; Cells, Cultured; Cerebral Cortex; Cyclic CMP; Cystine; Glutamic Acid; Glutathione; NF-E2-Related Factor 2; Rats; Reactive Oxygen Species; RNA, Messenger; Tritium | 2011 |
Insulin-like growth factor 1 and transforming growth factor-β stimulate cystine/glutamate exchange activity in dental pulp cells.
Topics: Amino Acid Transport System y+; Antimetabolites; Antioxidants; Buthionine Sulfoximine; Cells, Cultured; Composite Resins; Cystine; Dental Pulp; Glutamic Acid; Glutathione; Humans; Insulin-Like Growth Factor I; Pulp Capping and Pulpectomy Agents; Transforming Growth Factor beta | 2011 |
Regulation of System xc(-) by Pharmacological Manipulation of Cellular Thiols.
Topics: Amino Acid Transport System y+; Animals; Buthionine Sulfoximine; Carbon Isotopes; Cystine; Female; Glutathione; Maleates; Mice; Neurotoxins; Oxidative Stress; Sulfhydryl Compounds | 2015 |
Role of ferritinophagy in cystine deprivation-induced cell death in glioblastoma cells.
Topics: Antimetabolites, Antineoplastic; Autophagy; Brain Neoplasms; Buthionine Sulfoximine; Cell Death; Cell Line, Tumor; Cystine; Ferritins; Ferroptosis; Glioblastoma; Glutathione; Humans; Iron; Lipid Peroxidation; Oxidoreductases | 2021 |