cysteine has been researched along with vitamin k semiquinone radical in 53 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 30 (56.60) | 18.7374 |
| 1990's | 11 (20.75) | 18.2507 |
| 2000's | 7 (13.21) | 29.6817 |
| 2010's | 4 (7.55) | 24.3611 |
| 2020's | 1 (1.89) | 2.80 |
| Authors | Studies |
|---|---|
| Manjula, BN; Richards, FF; Rosenstein, RW | 1 |
| Duerden, BI | 1 |
| Bhatnagar, A; Liu, SQ; Petrash, JM; Srivastava, SK | 1 |
| Fujimoto, M; Hirata, M; Ohno, K | 1 |
| Akman, SA; Block, JS; Chlebowski, RT; Dietrich, MF; Doroshow, JH | 1 |
| Brötell, H; Karg, E; Rorsman, H; Rosengren, E | 1 |
| Orrenius, S | 1 |
| Akman, SA; Block, JB; Chlebowski, R; Dietrich, M; Limberg, P | 1 |
| Dely, M; Gábriel, M; Práger, P; Puppi, A; Szabó, IT | 1 |
| Bellomo, G; DiMonte, D; Mirabelli, F; Orrenius, C; Orrenius, S; Richelmi, P; Thor, H | 1 |
| Dely, M; Gábriel, M; Puppi, A; Szabó, IT | 1 |
| Chapman, JD; Greenstock, CL; Raleigh, JA; Reuvers, AP; Shiermen, E | 1 |
| de Lucca, O; Hadler, WA; Petelli, AS; Ziti, LM | 1 |
| Mikulski, T | 1 |
| Nelson, BD | 1 |
| Petering, DH; Shih, NT | 1 |
| Hayakawa, Y; Takamura, K | 1 |
| Czech, MP; Fain, JN | 1 |
| Markley, K; Shapiro, HM; Smallman, E | 1 |
| Lavis, V; Sakai, T; Williams, RH | 1 |
| Balerna, M; Keller-Schierlein, W; Martius, C; Wolf, H; Zähner, H | 1 |
| Ambrogi, V; Artini, D; Castellino, S; De Carneri, I; Di Somma, M; Dradi, E; Logemann, W; Meinardi, G; Tosolini, G; Vecchi, E | 1 |
| Tracy, O | 1 |
| Ichikawa, H; Ozawa, H | 1 |
| Gold, BK; Rosenthal, NA; Shapiro, R | 1 |
| Heisler, CR; Yang, HY | 1 |
| Carr, BI; Dowd, P; Finn, F; Kar, S; Kerns, J; Naganathan, S; Nishikawa, Y; Wang, M; Zheng, ZB | 1 |
| Hägerhäll, C; Hederstedt, L; Ohnishi, T; Sled, V | 1 |
| Kiss, Z; Tomono, M | 1 |
| Baker, ER; Baker, H; DeAngelis, B; Frank, O; Hutner, SH; Khalil, M | 1 |
| Bertina, RM; d Berg, M; Girolami, A; Simioni, P; Wojcik, EG | 1 |
| Peter-Katalinić, J; Rizner, TL; Strupat, K; Zakelj-Mavric, M; Zorko, M | 1 |
| Bridgeman, MM; Garner, M; Reglinski, J; Vallis, KA; Wolf, CR | 1 |
| Bouchard, BA; Furie, B; Furie, BC | 1 |
| Amzel, LM; Bianchet, MA; Foster, CE; Talalay, P; Zhao, Q | 1 |
| Chen, AY; LaVoie, EJ; Liu, LF; Mao, Y; Wang, H; Zhou, N | 1 |
| Berkner, KL; Hallgren, KW; Hommema, EL; Lee, S; McNally, BA; Pudota, BN | 1 |
| Carrick, KL; Mutucumarana, VP; Pope, RM; Stafford, DW; Straight, DL; Tie, JK | 1 |
| CATER, DB; PHILLIPS, AF | 1 |
| CRUZ-COKE, E | 1 |
| LIN, JK | 1 |
| ISHII, Y; TAKEISHI, T | 1 |
| OERIU, S; TANASE, I | 2 |
| Berkner, KL; Hallgren, KW; Pudota, BN; Qian, W; Rishavy, MA; Runge, KW; Song, JH; Yakubenko, AV | 1 |
| Jin, DY; Loiselle, DR; Pope, RM; Stafford, DW; Straight, DL; Tie, JK | 1 |
| Hutson, SM; Sane, DC; Wajih, N; Wallin, R | 1 |
| Bandyopadhyay, PK; Clark, K; Golic, KG; Olivera, BM; Rivier, JE; Rong, YS; Stevenson, BJ | 1 |
| Berkner, KL; Hallgren, KW; Rishavy, MA; Usubalieva, A | 1 |
| Jin, DY; Stafford, DW; Tie, JK | 1 |
| García-Fontana, C; Krell, T; Ortega, Á; Ramos, JL; Silva-Jiménez, H | 1 |
| Jin, DY; Sinhadri, BCS; Stafford, DW; Tie, JK | 1 |
| Krezel, AM; Li, S; Li, W; Liu, S; Shen, G; Sukumar, N | 1 |
1 review(s) available for cysteine and vitamin k semiquinone radical
| Article | Year |
|---|---|
[Electron spin resonance and its application in biochemistry].
Topics: Ascorbic Acid; Biochemical Phenomena; Biochemistry; Chemical Phenomena; Chemistry; Cysteine; Electron Spin Resonance Spectroscopy; Free Radicals; Methemoglobin; Nucleotides; Vitamin K | 1969 |
52 other study(ies) available for cysteine and vitamin k semiquinone radical
| Article | Year |
|---|---|
The distance between the contact sites for DNP and menadione ligands in the combining region of myeloma proteins binding both haptens--I. Estimation of distance by fluorescent energy transfer in protein 460.
Topics: Animals; Binding Sites, Antibody; Binding, Competitive; Cysteine; Dinitrobenzenes; Energy Transfer; Haptens; Immunoglobulin A; Mice; Myeloma Proteins; Nitrobenzenes; Spectrometry, Fluorescence; Vitamin K | 1976 |
Pigment production by Bacteroides species with reference to sub-classification.
Topics: Agar; Animals; Anti-Bacterial Agents; Bacteroides; Blood; Cysteine; Escherichia coli; Ferrous Compounds; Horses; Humans; Hydrogen Sulfide; Microbial Sensitivity Tests; Pigments, Biological; Spectrophotometry; Staphylococcus; Sulfates; Vitamin K | 1975 |
Mechanism of inhibition of aldose reductase by menadione (vitamin K3).
Topics: Aldehyde Reductase; Cysteine; Female; Humans; Kinetics; Mutagenesis, Site-Directed; Placenta; Pregnancy; Recombinant Proteins; Vitamin K | 1992 |
Protective effect of prostaglandin A2 against menadione-induced cell injury in cultured porcine aorta endothelial cells.
Topics: Animals; Aorta; Cells, Cultured; Cysteine; Dose-Response Relationship, Drug; Endothelium, Vascular; Glutathione; Methionine; Prostaglandins A; Pyrrolidonecarboxylic Acid; Swine; Thiazoles; Thiazolidines; Time Factors; Vitamin K | 1991 |
Synergistic cytotoxicity between menadione and dicumarol vs. murine leukemia L1210.
Topics: Adenosine Triphosphate; Animals; Antineoplastic Combined Chemotherapy Protocols; Calcium; Cell Division; Cysteine; Dicumarol; Drug Synergism; Glutathione; Leukemia L1210; Mice; NADP; Oxidation-Reduction; Oxygen Consumption; Quinones; Vitamin K | 1987 |
Modulation of glutathione level in cultured human melanoma cells.
Topics: Antimetabolites; Buthionine Sulfoximine; Cell Line; Cell Survival; Cysteine; Glutathione; Humans; Melanoma; Methionine Sulfoximine; Tumor Cells, Cultured; Vitamin K | 1989 |
Oxidative stress studied in intact mammalian cells.
Topics: Animals; Calcium; Cell Compartmentation; Cell Survival; Cysteine; Glutathione; Homeostasis; Humans; Liver; Oxygen; Proteins; Quinones; Stress, Physiological; Vitamin K | 1985 |
Modulation of cytotoxicity of menadione sodium bisulfite versus leukemia L1210 by the acid-soluble thiol pool.
Topics: Animals; Cysteine; Dose-Response Relationship, Drug; Glutathione; Kinetics; Leukemia L1210; Mice; NADP; Oxidation-Reduction; Superoxides; Vitamin K; Vitamin K 3 | 1985 |
Correlations between positive and negative aeroions, tissue redox-state potential and heart frequency in rats.
Topics: Animals; Cysteine; Electrophysiology; Female; Heart Rate; Ions; Liver; Male; Muscles; Oxidation-Reduction; Oxygen Consumption; Rats; Thiamine; Vitamin K | 1987 |
Formation and reduction of glutathione-protein mixed disulfides during oxidative stress. A study with isolated hepatocytes and menadione (2-methyl-1,4-naphthoquinone).
Topics: Animals; Calcium; Cell Survival; Cysteine; Cytosol; Disulfides; Dose-Response Relationship, Drug; Glutathione; Glutathione Reductase; In Vitro Techniques; Liver; Male; Mitochondria, Liver; Oxidation-Reduction; Proteins; Rats; Rats, Inbred Strains; Vitamin K | 1987 |
Correlations between redox-state potential changes in different tissues and the heart frequency in vivo.
Topics: Animals; Cysteine; Heart Rate; Heart Ventricles; Methylene Blue; Oxidation-Reduction; Rats; Rats, Inbred Strains; Stimulation, Chemical; Thiamine; Vitamin K | 1986 |
Competitive radioprotection and radiosensitization in chemical systems.
Topics: Acetophenones; Ascorbic Acid; Binding, Competitive; Cyclic N-Oxides; Cysteamine; Cysteine; Dithiothreitol; DNA; Ethylmaleimide; Histamine; Metronidazole; NAD; NADP; Nitro Compounds; Nitrobenzenes; Nitrofurantoin; Nitrofurazone; Nitrophenols; Oxygen; Paraquat; Promethazine; Pyridinium Compounds; Quinones; Radiation Effects; Radiation-Protective Agents; Radiation-Sensitizing Agents; Tetrazolium Salts; Vitamin K | 1974 |
The meaning of the selective staining of neurosecretory substance by aldehyde-fuchsin and chrome-alum hematoxylin. A comparative study carried on neurosecretory substance, cystine, cysteine and some unsaturated compounds subjected to several oxidizing age
Topics: Animals; Cattle; Chemical Phenomena; Chemistry; Cholesterol; Cysteine; Cystine; Ergocalciferols; Histocytochemistry; Neurosecretion; Oxidation-Reduction; Phenolphthaleins; Pituitary Gland, Posterior; Rats; Rosaniline Dyes; Staining and Labeling; Vitamin A; Vitamin E; Vitamin K | 1968 |
Action of the fungicides captan and folpet on rat liver mitochondria.
Topics: Adenosine Triphosphatases; Adenosine Triphosphate; Aniline Compounds; Animals; Antifungal Agents; Ascorbic Acid; Cysteine; Cytochromes; Dinitrophenols; Electron Transport; Enzyme Activation; Ferricyanides; Glutamates; Hydroxybutyrate Dehydrogenase; Hydroxybutyrates; Imines; In Vitro Techniques; Indoles; Kinetics; Magnesium; Membranes; Mitochondria, Liver; NAD; Oligomycins; Oxidative Phosphorylation; Oxidoreductases; Phosphates; Phosphorus Isotopes; Polarography; Quinones; Rats; Rotenone; Succinate Dehydrogenase; Succinates; Uncoupling Agents; Vitamin K | 1971 |
Model reactions for the study of the interaction of sulfur dioxide with mammalian organisms.
Topics: Chemical Phenomena; Chemistry; Cysteine; Cytidine; Kinetics; Mathematics; NAD; Spectrophotometry, Ultraviolet; Sulfites; Sulfonic Acids; Sulfur Dioxide; Thiamine Pyrophosphate; Vitamin K | 1973 |
[Reaction of vitamin K3 with cysteine in aqueous ethanol and consecutive determination of vitamins K (author's transl)].
Topics: Cysteine; Ethanol; Oxygen; Polarography; Vitamin K; Vitamin K 1 | 1974 |
Cu ++ -dependent thiol stimulation of glucose metabolism in white fat cells.
Topics: Adipose Tissue; Albumins; Animals; Calcium; Carbon Dioxide; Carbon Isotopes; Chromatography, Gel; Copper; Cysteine; Dialysis; Edetic Acid; Fatty Acids; Female; Glucose; Glutathione; Glycerol; Insulin; Magnesium; Osmolar Concentration; Phenanthrolines; Rats; Sucrose; Sulfhydryl Compounds; Vitamin K | 1972 |
Modification of burn shock mortality in mice by an oxidizing and a reducing agent.
Topics: Animals; Burns; Cysteine; Female; Mice; Organophosphorus Compounds; Oxidation-Reduction; Shock, Traumatic; Sodium Chloride; Solutions; Vitamin K | 1973 |
Incorporation of leucine into protein by isolated fat cells--effects of agents which stimulate glucose metabolism and inhibit lipolysis.
Topics: Adenine Nucleotides; Adipose Tissue; Animals; Concanavalin A; Cysteine; Glucose; In Vitro Techniques; Insulin; Leucine; Lipid Metabolism; Nystatin; Ouabain; Polyamines; Propylamines; Protein Biosynthesis; Pyruvates; Rats; Spermidine; Swine; Tolbutamide; Tritium; Vitamin K | 1973 |
[Metabolic products of microorganisms. 72. Naphthomycin, an antimetabolite of vitamin K].
Topics: Absorption; Anti-Bacterial Agents; Bacillus subtilis; Chromatography, Thin Layer; Crystallization; Cysteine; Drug Antagonism; Fungi; Molecular Weight; Spectrum Analysis; Streptomyces; Sulfhydryl Compounds; Ultraviolet Rays; Vitamin K | 1969 |
Studies on the antibacterial and antifungal properties of 1, 4-naphthoquinones.
Topics: Agar; Antifungal Agents; Bacteria; Candida; Cysteine; Densitometry; Enterococcus faecalis; Escherichia coli; Glutathione; Methods; Naphthoquinones; Oxygen Consumption; Polarography; Shigella sonnei; Spectrum Analysis; Staphylococcus; Ubiquinone; Ultraviolet Rays; Vitamin K | 1970 |
Pigment production in bacteroides.
Topics: Bacteroides; Culture Media; Cysteine; Iron; Pigments, Biological; Species Specificity; Sulfides; Vitamin K | 1969 |
[Studies on inhibitors of cholesterol biosynthesis. II. Effects of benzoquinone and naphthoquinone derivatives on the incorporation of acetate-1-14C into cholesterol in rat liver homogenates].
Topics: Acetates; Adenosine Triphosphate; Animals; Carbon Isotopes; Cholesterol; Cysteine; In Vitro Techniques; Liver; Male; Naphthoquinones; Oxidative Phosphorylation; Quinones; Rats; Vitamin K | 1970 |
Studies on the cause of a hemorrhagic syndrome in rats fed a water-soluble chemically defined diet.
Topics: Amino Acids; Animal Nutritional Physiological Phenomena; Animals; Antimetabolites; Ascorbic Acid; Cysteine; Diet; Dietary Fats; Ethers; Fats; Genetics; Hypoprothrombinemias; Linoleic Acids; Male; Phosphates; Prothrombin Time; Rats; Solubility; Species Specificity; Stimulation, Chemical; Vitamin A; Vitamin E; Vitamin K; Vitamin K Deficiency; Water | 1969 |
Non-stoichiometric sulfhydryl loss with vitamin K5.
Topics: Alcohol Oxidoreductases; Amylases; Catalase; Chemical Phenomena; Chemistry; Cysteine; Glutathione; Sulfhydryl Compounds; Vitamin K | 1966 |
Growth inhibition of hepatoma cells induced by vitamin K and its analogs.
Topics: Amino Acid Sequence; Blotting, Northern; Carcinoma, Hepatocellular; Catalase; Cell Division; Cell Line; Cysteine; Deferoxamine; DNA Damage; Gene Expression; Genes, myc; Glutathione; Humans; Ligases; Liver Neoplasms; Molecular Sequence Data; Molecular Structure; Oligopeptides; Structure-Activity Relationship; Tumor Cells, Cultured; Vitamin K | 1995 |
The trinuclear iron-sulfur cluster S3 in Bacillus subtilis succinate:menaquinone reductase; effects of a mutation in the putative cluster ligation motif on enzyme activity and EPR properties.
Topics: Amino Acid Sequence; Bacillus subtilis; Cysteine; Electron Spin Resonance Spectroscopy; Electron Transport Complex II; Iron; Molecular Sequence Data; Multienzyme Complexes; Mutagenesis, Site-Directed; Oxidoreductases; Succinate Dehydrogenase; Sulfur; Vitamin K | 1995 |
Vitamin K3 preferentially inhibits stimulation of phospholipase D-mediated hydrolysis of phosphatidylethanolamine by protein kinase C activators in NIH 3T3 fibroblasts.
Topics: 3T3 Cells; Animals; Cysteine; Enzyme Activation; Glutathione; Hydrolysis; Mice; Phosphatidylethanolamines; Phospholipase D; Platelet-Derived Growth Factor; Protein Kinase C; Superoxides; Tetradecanoylphorbol Acetate; Vitamin K; Xanthine; Xanthine Oxidase; Xanthines | 1994 |
Antioxidant survey to assess antagonism to redox stress using a prokaryotic and an eukaryotic system.
Topics: Antioxidants; Buthionine Sulfoximine; Cysteine; Escherichia coli; Eukaryota; Free Radicals; Glutathione; Homocysteine; Methionine Sulfoximine; Oxidative Stress; Pyrrolidonecarboxylic Acid; Thiazoles; Thiazolidines; Vitamin K; Vitamin K 3 | 1996 |
Mutations which introduce free cysteine residues in the Gla-domain of vitamin K dependent proteins result in the formation of complexes with alpha 1-microglobulin.
Topics: Alpha-Globulins; Amino Acid Sequence; Blood Coagulation Factors; Cysteine; Humans; Molecular Sequence Data; Molecular Weight; Mutation; Osteocalcin; Vitamin K | 1996 |
Carbonyl reducing 17 beta-hydroxysteroid dehydrogenase from the filamentous fungus Cochliobolus lunatus.
Topics: Alcohol Oxidoreductases; Aldehyde Reductase; Aldo-Keto Reductases; Androstenedione; Ascomycota; Binding Sites; Binding, Competitive; Cysteine; Diethyl Pyrocarbonate; Dithionitrobenzoic Acid; Histidine; Hydroxysteroid Dehydrogenases; Immunoblotting; Kinetics; Lysine; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Spectrophotometry, Ultraviolet; Tetranitromethane; Trinitrobenzenesulfonic Acid; Tyrosine; Vitamin K | 1997 |
Menadione-resistant Chinese hamster ovary cells have an increased capacity for glutathione synthesis.
Topics: Animals; CHO Cells; Chromatography, High Pressure Liquid; Cricetinae; Cysteine; Glutathione; Hemostatics; Magnetic Resonance Spectroscopy; Sulfhydryl Compounds; Time Factors; Vitamin K | 1997 |
Glutamyl substrate-induced exposure of a free cysteine residue in the vitamin K-dependent gamma-glutamyl carboxylase is critical for vitamin K epoxidation.
Topics: Amino Acid Sequence; Animals; Binding Sites; Carbon-Carbon Ligases; Cysteine; Enzyme Activation; Epoxy Compounds; Ethylmaleimide; Glutamic Acid; Humans; Molecular Sequence Data; Oligopeptides; Peptides; Protein Precursors; Substrate Specificity; Sulfhydryl Reagents; Vitamin K | 1999 |
Crystal structure of human quinone reductase type 2, a metalloflavoprotein.
Topics: Animals; Binding Sites; Copper; Crystallization; Crystallography, X-Ray; Cysteine; Flavin-Adenine Dinucleotide; Flavoproteins; Histidine; Humans; Metalloproteins; Mice; NAD(P)H Dehydrogenase (Quinone); Rats; Solutions; Vitamin K | 1999 |
Stimulation of topoisomerase II-mediated DNA damage via a mechanism involving protein thiolation.
Topics: Alanine; Alkylation; Animals; Cysteine; DNA Damage; DNA Topoisomerases, Type II; Drosophila; Humans; Intercalating Agents; KB Cells; Mutagenesis, Site-Directed; Naphthoquinones; Quinones; Sulfhydryl Compounds; Tumor Cells, Cultured; Vitamin K | 2001 |
Identification of sequences within the gamma-carboxylase that represent a novel contact site with vitamin K-dependent proteins and that are required for activity.
Topics: Amino Acid Sequence; Amino Acids; Animals; Baculoviridae; Binding Sites; Blotting, Western; Carbon-Carbon Ligases; Catalysis; Catalytic Domain; Cell Line; Cysteine; DNA, Complementary; Electrophoresis, Polyacrylamide Gel; Humans; Hydrogen-Ion Concentration; Insecta; Ions; Kinetics; Molecular Sequence Data; Mutagenesis, Site-Directed; Peptides; Phenylalanine; Protein Binding; Protein Precursors; Protein Structure, Tertiary; Prothrombin; Rabbits; Recombinant Proteins; Sequence Homology, Amino Acid; Serine; Tyrosine; Vitamin K | 2001 |
Determination of disulfide bond assignment of human vitamin K-dependent gamma-glutamyl carboxylase by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry.
Topics: Amino Acid Sequence; Animals; Binding Sites; Carbon-Carbon Ligases; Cell Line; Chymotrypsin; Cysteine; Disulfides; Glycosylation; Humans; Insecta; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; Peptides; Protein Structure, Tertiary; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Trypsin; Vitamin K | 2003 |
Protection by cysteine against the acute toxicity of a chemical radio-sensitizer (synkavit).
Topics: Cysteine; Drug-Related Side Effects and Adverse Reactions; Glutathione; Radiation-Sensitizing Agents; Vitamin K | 1956 |
A colour reaction of vitamin E with vitamin K and cysteine.
Topics: Color; Cysteine; Humans; Vitamin E; Vitamin K | 1958 |
The in vitro inhibition of catalase activity by several metabolites of amino acid.
Topics: Ascorbic Acid; Catalase; Cysteine; Glutathione; Humans; In Vitro Techniques; Liver; Tyrosine; Uric Acid; Vitamin K; Xanthines | 1962 |
[Side-effects of antineoplastic agents and their treatment].
Topics: Adrenochrome; Antineoplastic Agents; Cysteine; Glycine; Humans; Leukopenia; Vitamin A; Vitamin K; Vitamins | 1963 |
[BIOCHEMICAL ASPECTS OF THE AGING PROCESS. II. THE EFFECT OF CYSTEINE AND VITAMINS PLAYING A ROLE IN SULFUR METHYLATION AND METABOLISM ON AMINO ACID METABOLISM IN THE SPINAL CORD OF RATS OF DIFFERENT AGES].
Topics: Aging; Amino Acids; Corrinoids; Cysteine; Folic Acid; Methylation; Pharmacology; Proteins; Pyridoxine; Rats; Research; Spinal Cord; Sulfur; Vitamin A; Vitamin B 12; Vitamin K; Vitamins | 1963 |
[BIOCHEMICAL ASPECTS OF THE AGING PROCESS. III. THE EFFECT OF CYSTEINE AND VITAMINS PLAYING A ROLE IN METHYLATION AND METABOLISM OF SULFUR ON AMINO ACID METABOLISM IN THE MESENCEPHALON OF RATS OF DIFFERENT AGES].
Topics: Aging; Amino Acids; Corrinoids; Cysteine; Folic Acid; Mesencephalon; Methylation; Pharmacology; Proteins; Pyridoxine; Rats; Research; Sulfur; Vitamin A; Vitamin B 12; Vitamin K; Vitamins | 1963 |
A new model for vitamin K-dependent carboxylation: the catalytic base that deprotonates vitamin K hydroquinone is not Cys but an activated amine.
Topics: Amines; Animals; Baculoviridae; Carbon-Carbon Ligases; Catalysis; Cell Line; Cysteine; Cystine; Genetic Vectors; Hydroquinones; Insecta; Microsomes; Recombinant Proteins; Substrate Specificity; Vitamin K | 2004 |
Chemical modification of cysteine residues is a misleading indicator of their status as active site residues in the vitamin K-dependent gamma-glutamyl carboxylation reaction.
Topics: Amino Acid Sequence; Binding Sites; Carbon-Carbon Ligases; Cysteine; Enzyme Inhibitors; Maleimides; Molecular Sequence Data; Molecular Structure; Mutagenesis, Site-Directed; Peptide Fragments; Point Mutation; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Stilbenes; Structure-Activity Relationship; Sulfates; Sulfhydryl Reagents; Sulfonic Acids; Trypsin; Vitamin K | 2004 |
Engineering of a recombinant vitamin K-dependent gamma-carboxylation system with enhanced gamma-carboxyglutamic acid forming capacity: evidence for a functional CXXC redox center in the system.
Topics: Animals; Binding Sites; Blotting, Western; Carboxylic Acids; Cell Line; Cell Line, Tumor; Cloning, Molecular; Cricetinae; Cysteine; DNA; DNA, Complementary; Electrophoresis, Gel, Two-Dimensional; Electrophoresis, Polyacrylamide Gel; Factor X; Genetic Vectors; Liver; Male; Microsomes; Microsomes, Liver; Mixed Function Oxygenases; Mutagenesis, Site-Directed; Mutation; Oxidation-Reduction; Peptides; Plasmids; Protein Engineering; Protein Structure, Tertiary; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Serine; Thioredoxins; Transfection; Vitamin K; Vitamin K Epoxide Reductases | 2005 |
Biochemical characterization of Drosophila gamma-glutamyl carboxylase and its role in fly development.
Topics: Alanine; Amino Acid Substitution; Animals; Carbon-Carbon Ligases; Cell Line; Cysteine; Drosophila; Fertility; Humans; Mutagenesis, Site-Directed; Peptides; Vitamin K | 2006 |
Novel insight into the mechanism of the vitamin K oxidoreductase (VKOR): electron relay through Cys43 and Cys51 reduces VKOR to allow vitamin K reduction and facilitation of vitamin K-dependent protein carboxylation.
Topics: Animals; Catalysis; Cell Membrane; Cells, Cultured; Cysteine; Disulfides; Electrons; Enzyme Activation; Humans; Insecta; Microsomes; Mixed Function Oxygenases; Mutagenesis, Site-Directed; Oxidation-Reduction; Thioredoxin-Disulfide Reductase; Thioredoxins; Vitamin K; Vitamin K 1; Vitamin K Epoxide Reductases | 2011 |
Mycobacterium tuberculosis vitamin K epoxide reductase homologue supports vitamin K-dependent carboxylation in mammalian cells.
Topics: Cells, Cultured; Cysteine; HEK293 Cells; Humans; Mixed Function Oxygenases; Mycobacterium tuberculosis; Vitamin K; Vitamin K Epoxide Reductases | 2012 |
Multiple signals modulate the activity of the complex sensor kinase TodS.
Topics: Bacterial Proteins; Cysteine; Gene Expression Regulation, Bacterial; Gene Expression Regulation, Enzymologic; Mutation; Protein Kinases; Pseudomonas putida; Vitamin K | 2015 |
Vitamin K epoxide reductase and its paralogous enzyme have different structures and functions.
Topics: Amino Acid Sequence; Catalytic Domain; Cell Line; Cell Membrane; Cysteine; HEK293 Cells; Humans; Structure-Activity Relationship; Vitamin K; Vitamin K Epoxide Reductases; Warfarin | 2017 |
Structural basis of antagonizing the vitamin K catalytic cycle for anticoagulation.
Topics: Animals; Anticoagulants; Biocatalysis; Blood Coagulation; Catalytic Domain; Crystallography, X-Ray; Cysteine; Humans; Hydrogen Bonding; Hydrophobic and Hydrophilic Interactions; Oxidation-Reduction; Protein Structure, Secondary; Takifugu; Vitamin K; Vitamin K Epoxide Reductases | 2021 |