cysteine and transforming growth factor beta

cysteine has been researched along with transforming growth factor beta in 65 studies

Research

Studies (65)

TimeframeStudies, this research(%)All Research%
pre-19901 (1.54)18.7374
1990's23 (35.38)18.2507
2000's28 (43.08)29.6817
2010's7 (10.77)24.3611
2020's6 (9.23)2.80

Authors

AuthorsStudies
Das, SK; Fanburg, BL; White, AC1
Brunner, AM; Cook, J; Lioubin, MN; Madisen, L; Malacko, AR; Marquardt, H; Neubauer, M; Purchio, AF; Shapiro, RA; Wang, WC1
Dodge, GR; Hassell, JR; Iozzo, RV; Kovalszky, I1
Danielpour, D; Joyce, ME; Morales, TI; Roberts, AB; Sobel, ME1
Brunner, AM; Lioubin, MN; Malacko, AR; Marquardt, H; Purchio, AF1
Crookston, KP; Gonias, SL1
Bickenbach, JR; Bundman, D; Krieg, T; Longley, MA; Roberts, AB; Roche, NS; Roop, DR; Rothnagel, JA; Sellheyer, K1
Factor, V; Kondaiah, P; Kopp, J; Nagy, P; Roberts, AB; Sanderson, N; Sporn, MB; Thorgeirsson, SS; Wakefield, L1
Amatayakul-Chantler, S; Böttinger, EP; Gakenheimer, K; Qian, SW; Roberts, AB; Sporn, MB1
Atzori, L; Dypbukt, JM; Grafström, RC; Hybbinette, SS; Moldéus, P1
Homandberg, GA; Hui, F; Meyers, R; Xie, DL1
Bonadio, J; D'Alessio, M; Lynch, JR; Pangilinan, T; Pereira, L; Ramirez, F; Sykes, B1
Lee, SJ; McPherron, AC1
Grütter, MG; Schlunegger, MP1
Fujii, H; Hamada, H; Ikeda, M; Meno, C; Saijoh, Y; Toyoda, Y; Yokoyama, M; Yokoyama, T1
Keski-Oja, J; Saharinen, J; Taipale, J1
Beavis, RC; Gleizes, PE; Mazzieri, R; Rifkin, DB; Shen, B1
Haniu, M; Hui, J; Katta, V; Le, J; Lee, R; Rohde, MF; Shimamoto, G; Young, Y1
George, S; Hansen, CS; Marion, CD; Smith, WC; Steele, K1
Damji, KF; Guernsey, DL; Gupta, SK; Hodge, WG; Neumann, PE1
Bonadio, J; Fang, J; Smiley, E; Yin, W1
Keene, DR; Oganesian, A; Sandell, LJ; Zhu, Y1
Bernabéu, C; Calés, C; Langa, C; Lastres, P; Letamendía, A; López-Bote, JP; Páez, E; Raab, U; Tapia, E; Velasco, B1
Fanburg, BL; Lanzillo, JJ; Lee, SL; Maloney, EK; White, AC1
Cadene, M; Downing, AK; Dwek, RA; Gleizes, PE; Harvey, DJ; Rifkin, DB; Rudd, PM; Weir, I; Wormald, MR1
Keski-Oja, J; Saharinen, J1
Blair, SS; Conley, CA; Gelbart, W; Olson, DJ; Ralston, A; Rohwer-Nutter, D; Silburn, R; Singer, MA1
Sule, SD; Wigley, FM1
Kärkkäinen, M; Keski-Oja, J; Koli, K; Saharinen, J1
Chen, NC; Chen, SM; Pu, Q; Zhang, B; Zhu, BF1
Berry, C; Kambadur, R; Langley, B; Sharma, M; Thomas, M1
Annes, JP; Chen, Y; Dabovic, B; Rifkin, DB1
Waring, RH; Wilkinson, LJ1
Burmester, JK; Polga, D; Salzman, SA; Zhang, KQ1
Birk, DE; Carlson, EC; Funderburgh, JL; Gendron, RL; Kao, WW; Liu, CY; Mamiya, K1
Asundi, V; Binnerts, ME; Boyle, B; Bright, J; Canté-Barrett, K; Chen, HT; Funk, W; Rupp, F; Sattari, P; Tang, T; Wen, X1
Almogy, N; Bernstein, J; Biton, S; Eshel, D; Oren, A; Rotman, G; Savitsky, K; Toporik, A1
Sun, PD; Zou, Z1
Deane, CM; Downing, AK; Hamilton, JM; O'Leary, JM; Sandell, LJ; Valeyev, NV1
Arvola, T; Isolauri, E; Laitinen, K; Lampi, AM; Moilanen, E; Ruuska, T1
Ali, T; Chen, Y; Kristina Downing, A; O'leary, JM; Rifkin, DB; Todorovic, V1
Sebti, SM; Wang, DA1
Blakytny, R; Brunner, G; Erkell, LJ1
Inoue, K; Kodai, S; Minamiyama, Y; Mizuguchi, S; Okada, S; Suehiro, S; Takemura, S; Tsukioka, T1
Chaubert, P; El Kochairi, I; Letovanec, I; Munier, FL; Schorderet, DF; Uffer, S1
Kinoshita, T; Miyake, H; Nakajima, H; Ohori, M; Warizaya, M; Yoshimura, S1
Ha, H; Jung, H; Seong, HA1
Izumo, T; Kondo, M; Nagai, A1
Jones, DP; Ramadan, B; Ramirez, A; Ritzenthaler, JD; Rivera, HN; Roman, J1
Bonin, M; Kautzmann, S; Krüger, R; Marx, FP; Riess, O1
Diaz, JM; Herrera, L; Romero, MP; Romero, P; Vogel, M1
Gong, QH; Liu, Z; Wang, YQ; Xie, LX1
Darwiche, H; Oh, SH; Petersen, BE; Pintilie, DG; Salganik, SV; Shupe, TD1
Chang, SH; Harocopos, GJ; Huang, AJ; Patel, DA; Thang, DH; Vora, SC1
Mueller, TD; Nickel, J1
Chen, H; Fu, S; Geng, J; Jiang, Y; Jin, Y; Liu, D; Meng, X; Qu, H; Tong, D; Ye, S1
Maruyama, N; Ozawa, K; Takaiwa, F; Wakasa, Y; Yang, L1
Burke, TJ; Ritzenthaler, JD; Roman, J; Torres-González, E; Watson, WH; Zelko, IN1
Choi, SY; Choy, YB; Han, SM; Heo, CY; Kim, BH; Lee, SH; Park, CG; Park, HJ; Park, M1
Newfeld, SJ; Wisotzkey, RG1
Fujii, W; Inamochi, A; Kitamoto, K; Kuroda, M; Miyai, T; Ouchi, Y; Taketani, Y; Toyono, T; Usui, T; Yamagami, S1
Adams, SL; Brisson, BK; Burgwin, C; Chenoweth, D; Stewart, DC; Volk, SW; Wells, RG1
Huang, D; Li, X; Liu, D; Liu, J; Liu, Y; Luo, K; Mai, K; Pan, M; Wu, Z; Zhang, W1
Huang, C; Luo, H; Luo, Y; Wu, H; Zhang, Y1
Daly, SM; Newfeld, SJ; Peraza, A1

Reviews

2 review(s) available for cysteine and transforming growth factor beta

ArticleYear
Novel therapy in the treatment of scleroderma.
    Expert opinion on investigational drugs, 2001, Volume: 10, Issue:1

    Topics: Autoimmune Diseases; Bone Marrow Transplantation; Cysteine; Humans; Interferon-gamma; Nitric Oxide; Piperidines; Prostaglandins; Quinazolines; Quinazolinones; Relaxin; Scleroderma, Systemic; Tetracycline; Transforming Growth Factor beta; Tumor Necrosis Factor-alpha

2001
Promiscuity and specificity in BMP receptor activation.
    FEBS letters, 2012, Jul-04, Volume: 586, Issue:14

    Topics: Animals; Bone Morphogenetic Protein Receptors; Cysteine; Epitopes; Homeostasis; Humans; Hydrogen Bonding; Ligands; Models, Biological; Models, Molecular; Molecular Conformation; Phylogeny; Protein Binding; Protein Interaction Mapping; Signal Transduction; Time Factors; Transforming Growth Factor beta

2012

Other Studies

63 other study(ies) available for cysteine and transforming growth factor beta

ArticleYear
Modulation of transforming growth factor-beta 1 antiproliferative effects on endothelial cells by cysteine, cystine, and N-acetylcysteine.
    The Journal of clinical investigation, 1992, Volume: 90, Issue:5

    Topics: Acetylcysteine; Animals; Cattle; Cell Division; Cells, Cultured; Cysteine; Cystine; Endothelium, Vascular; Glutathione; Transforming Growth Factor beta; Tumor Cells, Cultured

1992
Site-directed mutagenesis of glycosylation sites in the transforming growth factor-beta 1 (TGF beta 1) and TGF beta 2 (414) precursors and of cysteine residues within mature TGF beta 1: effects on secretion and bioactivity.
    Molecular endocrinology (Baltimore, Md.), 1992, Volume: 6, Issue:10

    Topics: Amino Acid Sequence; Animals; Cell Division; Cell Line; CHO Cells; Cricetinae; Cysteine; Glycosylation; Mannosephosphates; Mutagenesis, Site-Directed; Protein Precursors; Recombinant Proteins; Restriction Mapping; Transfection; Transforming Growth Factor beta

1992
Transforming growth factor beta alters the expression of heparan sulfate proteoglycan in human colon carcinoma cells.
    The Journal of biological chemistry, 1990, Oct-15, Volume: 265, Issue:29

    Topics: Cell Line; Cell Nucleus; Chondroitin Sulfate Proteoglycans; Colonic Neoplasms; Cycloheximide; Cysteine; Dactinomycin; Heparan Sulfate Proteoglycans; Heparitin Sulfate; Humans; Kinetics; Molecular Weight; Poly A; RNA; RNA, Messenger; RNA, Neoplasm; Transcription, Genetic; Transforming Growth Factor beta

1990
Transforming growth factor-beta in calf articular cartilage organ cultures: synthesis and distribution.
    Archives of biochemistry and biophysics, 1991, Aug-01, Volume: 288, Issue:2

    Topics: Animals; Blotting, Northern; Cartilage, Articular; Cattle; Cysteine; Glycosaminoglycans; Kinetics; Organ Culture Techniques; Proteoglycans; RNA; Time Factors; Transforming Growth Factor beta

1991
Site-directed mutagenesis of cysteine residues in the pro region of the transforming growth factor beta 1 precursor. Expression and characterization of mutant proteins.
    The Journal of biological chemistry, 1989, Aug-15, Volume: 264, Issue:23

    Topics: Animals; Bacterial Proteins; Base Sequence; Cell Line; Codon; Cysteine; DNA, Single-Stranded; Genes; Molecular Sequence Data; Mutation; Protein Biosynthesis; Protein Precursors; Proteins; RNA, Bacterial; Transfection; Transforming Growth Factor beta; Transforming Growth Factors

1989
The role of cysteine-949 in the binding of transforming growth factor-beta 1 and transforming growth factor-beta 2 to alpha 2-macroglobulin.
    Biochemical and biophysical research communications, 1994, May-16, Volume: 200, Issue:3

    Topics: alpha-Macroglobulins; Cysteine; Disulfides; Humans; In Vitro Techniques; Iodoacetamide; Kinetics; Transforming Growth Factor beta

1994
Inhibition of skin development by overexpression of transforming growth factor beta 1 in the epidermis of transgenic mice.
    Proceedings of the National Academy of Sciences of the United States of America, 1993, Jun-01, Volume: 90, Issue:11

    Topics: Amino Acid Sequence; Animals; Animals, Newborn; Cysteine; DNA; Gene Expression; Immunohistochemistry; Introns; Mice; Mice, Transgenic; Microscopy, Electron; Mutagenesis, Site-Directed; Reference Values; RNA; Serine; Skin; Swine; Transforming Growth Factor beta

1993
Hepatic expression of mature transforming growth factor beta 1 in transgenic mice results in multiple tissue lesions.
    Proceedings of the National Academy of Sciences of the United States of America, 1995, Mar-28, Volume: 92, Issue:7

    Topics: Animals; Apoptosis; Cell Division; Cells, Cultured; Codon; Crosses, Genetic; Cysteine; DNA, Complementary; Female; Gene Expression; Glomerulonephritis; Inflammation; Kidney; Liver; Liver Cirrhosis, Experimental; Male; Mice; Mice, Inbred C57BL; Mice, Inbred CBA; Mice, Transgenic; Mitosis; Mutagenesis, Site-Directed; Myocardium; Restriction Mapping; Serine; Swine; Transforming Growth Factor beta

1995
[Ser77]transforming growth factor-beta 1. Selective biological activity and receptor binding in mink lung epithelial cells.
    The Journal of biological chemistry, 1994, Nov-04, Volume: 269, Issue:44

    Topics: Animals; Biological Assay; Cell Line; CHO Cells; Cricetinae; Cysteine; Disulfides; In Vitro Techniques; Mice; Mink; Models, Molecular; Mutagenesis, Site-Directed; Protein Conformation; Receptors, Transforming Growth Factor beta; Recombinant Proteins; Serine; Structure-Activity Relationship; Transforming Growth Factor beta

1994
Modifications of cellular thiols during growth and squamous differentiation of cultured human bronchial epithelial cells.
    Experimental cell research, 1994, Volume: 211, Issue:1

    Topics: Antimetabolites; Bronchi; Buthionine Sulfoximine; Calcium; Cell Differentiation; Cell Division; Cells, Cultured; Cysteine; Cystine; Epithelial Cells; Epithelium; Glutathione; Humans; Maleates; Methionine Sulfoximine; Oxidation-Reduction; Serum Albumin, Bovine; Sulfhydryl Compounds; Transforming Growth Factor beta

1994
Cartilage chondrolysis by fibronectin fragments is associated with release of several proteinases: stromelysin plays a major role in chondrolysis.
    Archives of biochemistry and biophysics, 1994, Volume: 311, Issue:2

    Topics: Animals; Blotting, Western; Cartilage, Articular; Cattle; Cells, Cultured; Cysteine; Enzyme Activation; Fibronectins; Gelatinases; Humans; Insulin-Like Growth Factor I; Interferon-gamma; Kinetics; Matrix Metalloproteinase 3; Metalloendopeptidases; Methionine; Peptide Fragments; Proteoglycans; Recombinant Proteins; Serine Endopeptidases; Sulfur Radioisotopes; Synovial Fluid; Time Factors; Transforming Growth Factor beta

1994
Genomic organization of the sequence coding for fibrillin, the defective gene product in Marfan syndrome.
    Human molecular genetics, 1993, Volume: 2, Issue:7

    Topics: Amino Acid Sequence; Base Sequence; Carrier Proteins; Chromosome Mapping; Chromosomes, Fungal; Cloning, Molecular; Cysteine; DNA; Epidermal Growth Factor; Exons; Fibrillins; Gene Library; Genome, Human; Humans; Intracellular Signaling Peptides and Proteins; Latent TGF-beta Binding Proteins; Marfan Syndrome; Microfilament Proteins; Molecular Sequence Data; Repetitive Sequences, Nucleic Acid; Transforming Growth Factor beta

1993
GDF-3 and GDF-9: two new members of the transforming growth factor-beta superfamily containing a novel pattern of cysteines.
    The Journal of biological chemistry, 1993, Feb-15, Volume: 268, Issue:5

    Topics: Amino Acid Sequence; Animals; Base Sequence; Bone Morphogenetic Protein 15; Cysteine; DNA; Female; Growth Differentiation Factor 3; Growth Differentiation Factor 9; Growth Substances; Humans; Intercellular Signaling Peptides and Proteins; Male; Mice; Molecular Sequence Data; Multigene Family; Oligodeoxyribonucleotides; Organ Specificity; Polymerase Chain Reaction; RNA, Messenger; Sequence Homology, Amino Acid; Transforming Growth Factor beta; Xenopus

1993
Refined crystal structure of human transforming growth factor beta 2 at 1.95 A resolution.
    Journal of molecular biology, 1993, May-20, Volume: 231, Issue:2

    Topics: Amino Acid Sequence; Cysteine; Humans; Hydrogen Bonding; Ions; Models, Chemical; Molecular Sequence Data; Proline; Protein Conformation; Protein Structure, Secondary; Recombinant Proteins; Transforming Growth Factor beta; Water; X-Ray Diffraction

1993
Left-right asymmetric expression of the TGF beta-family member lefty in mouse embryos.
    Nature, 1996, May-09, Volume: 381, Issue:6578

    Topics: 3T3 Cells; Amino Acid Sequence; Animals; Base Sequence; Chromosome Mapping; Cysteine; DNA; Embryo, Mammalian; Embryonic and Fetal Development; Left-Right Determination Factors; Mice; Mice, Inbred ICR; Molecular Sequence Data; Mutation; Transforming Growth Factor beta; Tumor Cells, Cultured

1996
Association of the small latent transforming growth factor-beta with an eight cysteine repeat of its binding protein LTBP-1.
    The EMBO journal, 1996, Jan-15, Volume: 15, Issue:2

    Topics: Amino Acid Sequence; Animals; Binding Sites; Carrier Proteins; Cell Line; Chlorocebus aethiops; CHO Cells; Cricetinae; Cysteine; Disulfides; Electrophoresis, Polyacrylamide Gel; Epidermal Growth Factor; Extracellular Matrix; Extracellular Matrix Proteins; Humans; Intracellular Signaling Peptides and Proteins; Kidney; Latent TGF-beta Binding Proteins; Models, Structural; Molecular Sequence Data; Polymerase Chain Reaction; Recombinant Proteins; Repetitive Sequences, Nucleic Acid; Transfection; Transforming Growth Factor beta

1996
Identification and characterization of an eight-cysteine repeat of the latent transforming growth factor-beta binding protein-1 that mediates bonding to the latent transforming growth factor-beta1.
    The Journal of biological chemistry, 1996, Nov-22, Volume: 271, Issue:47

    Topics: Animals; Carrier Proteins; Cell Line; CHO Cells; Cricetinae; Cysteine; Humans; Intracellular Signaling Peptides and Proteins; Latent TGF-beta Binding Proteins; Mutagenesis; Nucleopolyhedroviruses; Protein Binding; Recombinant Proteins; Sequence Deletion; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Spodoptera; Transforming Growth Factor beta

1996
Glial cell line-derived neurotrophic factor: selective reduction of the intermolecular disulfide linkage and characterization of its disulfide structure.
    Biochemistry, 1996, Dec-24, Volume: 35, Issue:51

    Topics: Amino Acid Sequence; Cell Line; Cysteine; Dimerization; Disulfides; Glial Cell Line-Derived Neurotrophic Factor; Humans; Molecular Sequence Data; Molecular Structure; Nerve Growth Factors; Nerve Tissue Proteins; Neuroglia; Oxidation-Reduction; Peptide Fragments; Peptide Mapping; Recombinant Proteins; Transforming Growth Factor beta

1996
Direct neural induction and selective inhibition of mesoderm and epidermis inducers by Xnr3.
    Development (Cambridge, England), 1997, Volume: 124, Issue:2

    Topics: Amino Acid Sequence; Animals; Conserved Sequence; Cysteine; Ectoderm; Embryo, Nonmammalian; Embryonic Induction; Epidermis; Female; Gastrula; Gene Expression Regulation, Developmental; Mesoderm; Mice; Mutagenesis, Site-Directed; Nervous System; Organ Culture Techniques; Receptors, Transforming Growth Factor beta; Recombinant Proteins; Transforming Growth Factor beta; Xenopus; Xenopus Proteins

1997
Lattice corneal dystrophy type 1 in a Canadian kindred is associated with the Arg124 --> Cys mutation in the kerato-epithelin gene. sgupta@ogh.on.ca.
    American journal of ophthalmology, 1998, Volume: 125, Issue:4

    Topics: Arginine; Canada; Chromosomes, Human, Pair 5; Corneal Dystrophies, Hereditary; Cysteine; DNA; DNA Primers; Extracellular Matrix Proteins; Female; Humans; Male; Neoplasm Proteins; Pedigree; Point Mutation; Polymerase Chain Reaction; Polymorphism, Single-Stranded Conformational; Transforming Growth Factor beta

1998
8-Cysteine TGF-BP structural motifs are the site of covalent binding between mouse LTBP-3, LTBP-2, and latent TGF-beta 1.
    Biochimica et biophysica acta, 1998, Apr-02, Volume: 1383, Issue:2

    Topics: Adaptor Proteins, Signal Transducing; Animals; Binding Sites; Carrier Proteins; Cysteine; Latent TGF-beta Binding Proteins; Mice; Protein Binding; Transforming Growth Factor beta

1998
Type IIA procollagen containing the cysteine-rich amino propeptide is deposited in the extracellular matrix of prechondrogenic tissue and binds to TGF-beta1 and BMP-2.
    The Journal of cell biology, 1999, Mar-08, Volume: 144, Issue:5

    Topics: Base Sequence; Bone Morphogenetic Protein 2; Bone Morphogenetic Proteins; Cartilage; Cysteine; DNA Primers; Extracellular Matrix; Fluorescent Antibody Technique; Humans; Microscopy, Immunoelectron; Procollagen; Protein Binding; Protein Isoforms; Recombinant Proteins; Transforming Growth Factor beta

1999
Expression of normal and truncated forms of human endoglin.
    The Biochemical journal, 1999, May-01, Volume: 339 ( Pt 3)

    Topics: Animals; Antigens, CD; Cell Line; Cell Membrane; Cysteine; Dimerization; Disulfides; Endoglin; Endothelium, Vascular; Gene Expression; Humans; Peptide Fragments; Protein Binding; Protein Isoforms; Receptors, Cell Surface; Recombinant Fusion Proteins; Reducing Agents; RNA, Messenger; Sequence Deletion; Solubility; Telangiectasia, Hereditary Hemorrhagic; Transfection; Transforming Growth Factor beta; Vaccinia virus; Vascular Cell Adhesion Molecule-1

1999
Reduction of endothelial cell related TGFbeta activity by thiols.
    Endothelium : journal of endothelial cell research, 1999, Volume: 6, Issue:3

    Topics: Acetylcysteine; Animals; Cattle; Cells, Cultured; Culture Media, Conditioned; Cysteine; Dose-Response Relationship, Drug; Endothelium, Vascular; Glutathione; Glutathione Disulfide; Oxidation-Reduction; Pulmonary Artery; Sulfhydryl Compounds; Swine; Transforming Growth Factor beta

1999
Hybrid and complex glycans are linked to the conserved N-glycosylation site of the third eight-cysteine domain of LTBP-1 in insect cells.
    Biochemistry, 2000, Feb-22, Volume: 39, Issue:7

    Topics: Amino Acid Sequence; Animals; Baculoviridae; Carbohydrate Conformation; Carrier Proteins; Cell Line; Chromatography, High Pressure Liquid; Conserved Sequence; Cysteine; Glycosylation; Humans; Intracellular Signaling Peptides and Proteins; Latent TGF-beta Binding Proteins; Molecular Sequence Data; Oligosaccharides; Peptide Fragments; Polysaccharides; Protein Structure, Tertiary; Recombinant Fusion Proteins; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Spodoptera; Transforming Growth Factor beta

2000
Specific sequence motif of 8-Cys repeats of TGF-beta binding proteins, LTBPs, creates a hydrophobic interaction surface for binding of small latent TGF-beta.
    Molecular biology of the cell, 2000, Volume: 11, Issue:8

    Topics: Amino Acid Motifs; Amino Acid Sequence; Carrier Proteins; Cysteine; Epithelial Cells; Fibrillins; Fibroblasts; Humans; Intracellular Signaling Peptides and Proteins; Latent TGF-beta Binding Proteins; Microfilament Proteins; Models, Molecular; Molecular Sequence Data; Protein Binding; Protein Isoforms; Protein Structure, Tertiary; Recombinant Fusion Proteins; Sequence Alignment; Transfection; Transforming Growth Factor beta

2000
Crossveinless 2 contains cysteine-rich domains and is required for high levels of BMP-like activity during the formation of the cross veins in Drosophila.
    Development (Cambridge, England), 2000, Volume: 127, Issue:18

    Topics: Alleles; Amino Acid Sequence; Animals; Base Sequence; Bone Morphogenetic Proteins; Cloning, Molecular; Cysteine; DNA-Binding Proteins; Drosophila melanogaster; Drosophila Proteins; Gene Expression Regulation, Developmental; Immunohistochemistry; In Situ Hybridization; Insect Proteins; Molecular Sequence Data; Mutation; Protein Structure, Tertiary; Sequence Homology, Amino Acid; Signal Transduction; Time Factors; Transcription Factors; Transforming Growth Factor beta; Veins; Wings, Animal

2000
Novel non-TGF-beta-binding splice variant of LTBP-4 in human cells and tissues provides means to decrease TGF-beta deposition.
    Journal of cell science, 2001, Volume: 114, Issue:Pt 15

    Topics: Adaptor Proteins, Signal Transducing; Alternative Splicing; Carrier Proteins; Cell Line, Transformed; Culture Media, Conditioned; Cysteine; DNA, Complementary; Fibroblasts; Gene Expression; Humans; Immunoblotting; Kidney; Latent TGF-beta Binding Proteins; Lung; Osteosarcoma; Phenotype; Repetitive Sequences, Amino Acid; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Skin; Transforming Growth Factor beta; Tumor Cells, Cultured; Umbilical Veins

2001
[Bone-inducing activity of human bone morphogenetic protein-2 102 peptide].
    Sheng wu gong cheng xue bao = Chinese journal of biotechnology, 2001, Volume: 17, Issue:6

    Topics: Animals; Biological Assay; Bone Morphogenetic Protein 2; Bone Morphogenetic Proteins; Cysteine; Escherichia coli; Femur; Humans; Mice; Osteogenesis; Peptide Fragments; Point Mutation; Protein Engineering; Recombinant Proteins; Transforming Growth Factor beta

2001
Single cysteine to tyrosine transition inactivates the growth inhibitory function of Piedmontese myostatin.
    American journal of physiology. Cell physiology, 2002, Volume: 283, Issue:1

    Topics: Amino Acid Substitution; Animals; Cattle; Cell Division; Cell Line; Cysteine; Growth Inhibitors; Muscles; Mutation; Myostatin; Reference Values; RNA Stability; RNA, Messenger; Transforming Growth Factor beta; Tyrosine

2002
Latent TGF-beta binding protein-3 (LTBP-3) requires binding to TGF-beta for secretion.
    FEBS letters, 2002, Apr-24, Volume: 517, Issue:1-3

    Topics: Adaptor Proteins, Signal Transducing; Animals; Carrier Proteins; Cells, Cultured; Cysteine; Disulfides; Humans; Intracellular Signaling Peptides and Proteins; Latent TGF-beta Binding Proteins; Mice; Protein Binding; Recombinant Fusion Proteins; Transfection; Transforming Growth Factor beta

2002
Cysteine dioxygenase: modulation of expression in human cell lines by cytokines and control of sulphate production.
    Toxicology in vitro : an international journal published in association with BIBRA, 2002, Volume: 16, Issue:4

    Topics: Antineoplastic Agents; Arthritis, Rheumatoid; Cell Line; Cysteine; Cysteine Dioxygenase; Dioxygenases; Humans; Inflammation; Liver; Neurons; Oxygenases; Sulfates; Transforming Growth Factor beta; Tumor Necrosis Factor-alpha

2002
Amino acids 67 and 68 of transforming growth factor-beta regulate binding to a glycosyl phosphatidyl inositol-linked membrane protein on vascular endothelial cells.
    Cytokines, cellular & molecular therapy, 2002, Volume: 7, Issue:1

    Topics: Amino Acid Sequence; Animals; Cattle; Cell Membrane; Cells, Cultured; CHO Cells; Cricetinae; Cross-Linking Reagents; Cysteine; Endothelium, Vascular; Isoleucine; Ligands; Models, Molecular; Molecular Sequence Data; Mutation; Plasmids; Protein Binding; Protein Structure, Secondary; Protein Structure, Tertiary; Recombinant Fusion Proteins; Sequence Homology, Amino Acid; Swine; Threonine; Transforming Growth Factor beta; Transforming Growth Factor beta1; Transforming Growth Factor beta2

2002
Role of Cys41 in the N-terminal domain of lumican in ex vivo collagen fibrillogenesis by cultured corneal stromal cells.
    The Biochemical journal, 2003, Feb-01, Volume: 369, Issue:Pt 3

    Topics: Amino Acid Sequence; Animals; Base Sequence; Cells, Cultured; Chondroitin Sulfate Proteoglycans; Corneal Stroma; Cysteine; Extracellular Matrix; Fibrillar Collagens; Keratan Sulfate; Lumican; Mice; Microscopy, Electron; Molecular Sequence Data; Mutation; Protein Structure, Tertiary; Transforming Growth Factor beta

2003
Human Crossveinless-2 is a novel inhibitor of bone morphogenetic proteins.
    Biochemical and biophysical research communications, 2004, Mar-05, Volume: 315, Issue:2

    Topics: Alkaline Phosphatase; Animals; Bone Morphogenetic Protein 2; Bone Morphogenetic Protein 4; Bone Morphogenetic Proteins; Cell Differentiation; Cell Division; Cell Line; Cells, Cultured; Cysteine; DNA, Complementary; Dose-Response Relationship, Drug; Drosophila; Drosophila Proteins; Glycoproteins; Humans; Intercellular Signaling Peptides and Proteins; Mice; Osteoblasts; Phenotype; Phosphorylation; Protein Structure, Tertiary; Recombinant Proteins; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Signal Transduction; Tissue Distribution; Transforming Growth Factor beta

2004
hCHL2, a novel chordin-related gene, displays differential expression and complex alternative splicing in human tissues and during myoblast and osteoblast maturation.
    Gene, 2004, Apr-28, Volume: 331

    Topics: Activins; Alternative Splicing; Amino Acid Sequence; Animals; Bone Morphogenetic Protein 2; Bone Morphogenetic Proteins; Carrier Proteins; Cell Differentiation; Cell Line; Cell Line, Tumor; Chlorocebus aethiops; Conserved Sequence; COS Cells; Cysteine; Evolution, Molecular; Extracellular Matrix Proteins; Female; Gene Expression Profiling; Humans; Inhibin-beta Subunits; Insulin; Male; Mice; Molecular Sequence Data; Myoblasts; Osteoblasts; Protein Binding; Protein Isoforms; Recombinant Proteins; Reverse Transcriptase Polymerase Chain Reaction; RNA; Sequence Homology, Amino Acid; Transforming Growth Factor beta

2004
Overexpression of human transforming growth factor-beta1 using a recombinant CHO cell expression system.
    Protein expression and purification, 2004, Volume: 37, Issue:2

    Topics: Animals; Biochemistry; Blotting, Western; Cell Culture Techniques; Cell Line; CHO Cells; Cricetinae; Cysteine; Disulfides; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Enzyme-Linked Immunosorbent Assay; Histidine; Humans; Mass Spectrometry; Models, Biological; Plasmids; Protein Binding; Protein Sorting Signals; Rats; Recombinant Proteins; Serum Albumin; Transforming Growth Factor beta; Transforming Growth Factor beta1

2004
Solution structure and dynamics of a prototypical chordin-like cysteine-rich repeat (von Willebrand Factor type C module) from collagen IIA.
    The Journal of biological chemistry, 2004, Dec-17, Volume: 279, Issue:51

    Topics: Algorithms; Amino Acid Sequence; Binding Sites; Collagen Type II; Cysteine; Cysteine-Rich Protein 61; Cytokines; Disulfides; Evolution, Molecular; Extracellular Matrix; Eye Proteins; Fibronectins; Glycoproteins; Humans; Immediate-Early Proteins; Intercellular Signaling Peptides and Proteins; Ligands; Magnetic Resonance Spectroscopy; Models, Molecular; Molecular Sequence Data; Nerve Tissue Proteins; Protein Binding; Protein Conformation; Protein Structure, Secondary; Protein Structure, Tertiary; Proteomics; Sequence Homology, Amino Acid; Software; Transforming Growth Factor beta; Transforming Growth Factor beta1; Vascular Endothelial Growth Factor A

2004
Characterization of breast milk received by infants with gross blood in stools.
    Biology of the neonate, 2005, Volume: 87, Issue:1

    Topics: Blood; Breast Feeding; Colitis; Cysteine; Dinoprostone; Fatty Acids; Feces; Female; Humans; Hypersensitivity; Immunoglobulin E; Infant; Infant, Newborn; Leukotrienes; Lipids; Logistic Models; Male; Milk, Human; Transforming Growth Factor beta; Transforming Growth Factor beta2; Tumor Necrosis Factor-alpha

2005
Amino acid requirements for formation of the TGF-beta-latent TGF-beta binding protein complexes.
    Journal of molecular biology, 2005, Jan-07, Volume: 345, Issue:1

    Topics: Amino Acid Sequence; Amino Acids; Animals; Binding Sites; Cell Line; Cysteine; Disulfides; Fluorescence Resonance Energy Transfer; Humans; Intracellular Signaling Peptides and Proteins; Latent TGF-beta Binding Proteins; Macromolecular Substances; Models, Molecular; Molecular Sequence Data; Mutation; Protein Binding; Protein Isoforms; Protein Structure, Tertiary; Sequence Alignment; TNF Receptor-Associated Factor 3; Transforming Growth Factor beta

2005
Palmitoylated cysteine 192 is required for RhoB tumor-suppressive and apoptotic activities.
    The Journal of biological chemistry, 2005, May-13, Volume: 280, Issue:19

    Topics: Alanine; Amino Acid Sequence; Apoptosis; Blotting, Western; Cell Cycle Proteins; Cell Line; Cell Line, Tumor; Cell Proliferation; Coloring Agents; Cyclin-Dependent Kinase Inhibitor p21; Cysteine; DNA Primers; Genes, Tumor Suppressor; Glycine; Humans; In Situ Nick-End Labeling; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; Palmitic Acid; Promoter Regions, Genetic; Protein Biosynthesis; Protein Prenylation; rhoA GTP-Binding Protein; rhoB GTP-Binding Protein; Sequence Homology, Amino Acid; Serine; Tetrazolium Salts; Thiazoles; Transcription Factor AP-1; Transcription, Genetic; Transfection; Transforming Growth Factor beta

2005
Inactivation of active and latent transforming growth factor beta by free thiols: potential redox regulation of biological action.
    The international journal of biochemistry & cell biology, 2006, Volume: 38, Issue:8

    Topics: Bacitracin; Blotting, Western; Cysteine; Dimerization; Dithiothreitol; Dose-Response Relationship, Drug; Glutathione; Homocysteine; Humans; Oxidation-Reduction; Recombinant Proteins; Sulfhydryl Compounds; Temperature; Transforming Growth Factor beta

2006
S-allyl cysteine attenuated CCl4-induced oxidative stress and pulmonary fibrosis in rats.
    BioFactors (Oxford, England), 2006, Volume: 26, Issue:1

    Topics: Animals; Bronchoalveolar Lavage Fluid; Carbon Tetrachloride; Cysteine; Enzyme Precursors; Glutathione; Hydroxyproline; Liver; Lung; Male; Matrix Metalloproteinase 9; Nitric Oxide; Nitric Oxide Synthase Type II; Oxidative Stress; Pulmonary Fibrosis; Rats; Rats, Wistar; Reactive Oxygen Species; Sulfhydryl Compounds; Transforming Growth Factor beta; Transforming Growth Factor beta1

2006
Systemic investigation of keratoepithelin deposits in TGFBI/BIGH3-related corneal dystrophy.
    Molecular vision, 2006, May-10, Volume: 12

    Topics: Aged; Arginine; Cornea; Corneal Dystrophies, Hereditary; Cysteine; DNA Mutational Analysis; Exons; Extracellular Matrix Proteins; Humans; Immunohistochemistry; Male; Pulmonary Disease, Chronic Obstructive; Tissue Distribution; Transforming Growth Factor beta

2006
Role of a cysteine residue in the active site of ERK and the MAPKK family.
    Biochemical and biophysical research communications, 2007, Feb-16, Volume: 353, Issue:3

    Topics: Amino Acid Sequence; Animals; Binding Sites; Cells, Cultured; Cysteine; Humans; Lactones; MAP Kinase Kinase 1; MAP Kinase Kinase 7; Mink; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase Kinases; p38 Mitogen-Activated Protein Kinases; Sequence Alignment; Transcription Factor AP-1; Transforming Growth Factor beta

2007
NM23-H1 tumor suppressor physically interacts with serine-threonine kinase receptor-associated protein, a transforming growth factor-beta (TGF-beta) receptor-interacting protein, and negatively regulates TGF-beta signaling.
    The Journal of biological chemistry, 2007, Apr-20, Volume: 282, Issue:16

    Topics: Active Transport, Cell Nucleus; Apoptosis; Cell Nucleus; Cell Separation; Cysteine; Gene Expression Regulation, Neoplastic; HeLa Cells; Humans; Mutation; Neoplasm Proteins; NM23 Nucleoside Diphosphate Kinases; Nucleoside-Diphosphate Kinase; Protein Binding; Protein Structure, Tertiary; Recombinant Proteins; RNA-Binding Proteins; Transforming Growth Factor beta

2007
Cysteinyl-leukotriene 1 receptor antagonist attenuates bleomycin-induced pulmonary fibrosis in mice.
    Life sciences, 2007, Apr-24, Volume: 80, Issue:20

    Topics: Animals; Bleomycin; Bronchoalveolar Lavage Fluid; Cysteine; Disease Models, Animal; Hydroxyproline; Leukotriene Antagonists; Leukotrienes; Male; Mice; Mice, Inbred C57BL; Pulmonary Fibrosis; Receptors, Leukotriene; Transforming Growth Factor beta

2007
Extracellular cysteine/cystine redox potential controls lung fibroblast proliferation and matrix expression through upregulation of transforming growth factor-beta.
    American journal of physiology. Lung cellular and molecular physiology, 2007, Volume: 293, Issue:4

    Topics: Animals; Cell Proliferation; Cyclic AMP Response Element-Binding Protein; Cysteine; Cystine; Enzyme Activation; Extracellular Fluid; Fibroblasts; Fibronectins; Lung; Mice; NF-kappa B; NIH 3T3 Cells; Oxidation-Reduction; Phosphorylation; Protein Kinase C; RNA, Messenger; Signal Transduction; Smad3 Protein; Transforming Growth Factor beta; Up-Regulation

2007
Microarray expression analysis reveals genetic pathways implicated in C621 synphilin-1-mediated toxicity.
    Journal of neural transmission (Vienna, Austria : 1996), 2008, Volume: 115, Issue:7

    Topics: Arginine; Carrier Proteins; Cell Line, Transformed; Cysteine; Gene Expression Regulation; Green Fluorescent Proteins; Humans; Mutation; Nerve Tissue Proteins; Oligonucleotide Array Sequence Analysis; Signal Transduction; Transfection; Transforming Growth Factor beta

2008
Anticipation in familial lattice corneal dystrophy type I with R124C mutation in the TGFBI (BIGH3) gene.
    Molecular vision, 2008, May-07, Volume: 14

    Topics: Adolescent; Adult; Aged; Amino Acid Sequence; Amino Acid Substitution; Arginine; Base Sequence; Child; Child, Preschool; Cornea; Corneal Dystrophies, Hereditary; Cysteine; DNA Mutational Analysis; Extracellular Matrix Proteins; Female; Humans; Male; Molecular Sequence Data; Mutation; Pedigree; Phenotype; Transforming Growth Factor beta

2008
An R124C mutation in TGFBI caused lattice corneal dystrophy type I with a variable phenotype in three Chinese families.
    Molecular vision, 2008, Jun-30, Volume: 14

    Topics: Adolescent; Adult; Amino Acid Substitution; Arginine; Asian People; Base Sequence; China; Corneal Dystrophies, Hereditary; Cysteine; DNA Mutational Analysis; Extracellular Matrix Proteins; Family; Female; Humans; Male; Molecular Sequence Data; Mutation; Pedigree; Phenotype; Transforming Growth Factor beta

2008
Hepatic stellate cells' involvement in progenitor-mediated liver regeneration.
    Laboratory investigation; a journal of technical methods and pathology, 2010, Volume: 90, Issue:8

    Topics: 2-Acetylaminofluorene; alpha-Fetoproteins; Animals; Connective Tissue Growth Factor; Cysteine; Hepatectomy; Hepatic Stellate Cells; Liver; Liver Diseases; Liver Regeneration; Male; Rats; Rats, Inbred F344; Stem Cells; Transforming Growth Factor beta

2010
Granular and lattice deposits in corneal dystrophy caused by R124C mutation of TGFBIp.
    Cornea, 2010, Volume: 29, Issue:11

    Topics: Adult; Amyloid; Antibody Specificity; Arginine; Benzothiazoles; Cornea; Corneal Dystrophies, Hereditary; Corneal Stroma; Cysteine; Extracellular Matrix Proteins; Fluorescent Antibody Technique; Fluorescent Dyes; Genotype; Heterozygote; Humans; Male; Mutation; Penetrance; Staining and Labeling; Thiazoles; Transforming Growth Factor beta

2010
S-allylmercaptocysteine promotes MAPK inhibitor-induced apoptosis by activating the TGF-β signaling pathway in cancer cells.
    Oncology reports, 2014, Volume: 32, Issue:3

    Topics: Apoptosis; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Proliferation; Cysteine; Drug Synergism; Gene Expression Regulation, Neoplastic; Hep G2 Cells; Humans; Liver Neoplasms; Protein Kinase Inhibitors; Signal Transduction; Transforming Growth Factor beta

2014
Deposition mode of transforming growth factor-β expressed in transgenic rice seed.
    Plant cell reports, 2016, Volume: 35, Issue:12

    Topics: Animals; Cysteine; Endosperm; Gene Expression Regulation, Plant; Intracellular Space; Mice; Oryza; Pepsin A; Plants, Genetically Modified; Prolamins; Protein Multimerization; Recombinant Proteins; Seeds; Transforming Growth Factor beta; Unfolded Protein Response

2016
Differential Regulation of the Extracellular Cysteine/Cystine Redox State (EhCySS) by Lung Fibroblasts from Young and Old Mice.
    Oxidative medicine and cellular longevity, 2016, Volume: 2016

    Topics: Actins; Aging; Animals; Cells, Cultured; Cysteine; Cystine; Fibroblasts; Fibronectins; Lung; Mice; Oxidation-Reduction; Superoxide Dismutase; Transforming Growth Factor beta

2016
Prolonged, acute suppression of cysteinyl leukotriene to reduce capsular contracture around silicone implants.
    Acta biomaterialia, 2017, 03-15, Volume: 51

    Topics: Adipose Tissue; Animals; Collagen; Cysteine; Female; Fibroblasts; Implants, Experimental; Inflammation; Lactic Acid; Leukotrienes; Macrophages; Microscopy, Electron, Scanning; Myofibroblasts; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Rats; Rats, Sprague-Dawley; Silicones; Transforming Growth Factor beta

2017
TGF-β Prodomain Alignments Reveal Unexpected Cysteine Conservation Consistent with Phylogenetic Predictions of Cross-Subfamily Heterodimerization.
    Genetics, 2020, Volume: 214, Issue:2

    Topics: Amino Acid Sequence; Animals; Caenorhabditis elegans; Cysteine; Drosophila melanogaster; Evolution, Molecular; Humans; Mice; Phylogeny; Protein Binding; Protein Domains; Sequence Alignment; Signal Transduction; Transforming Growth Factor beta

2020
Generation of mouse model of TGFBI-R124C corneal dystrophy using CRISPR/Cas9-mediated homology-directed repair.
    Scientific reports, 2020, 02-06, Volume: 10, Issue:1

    Topics: Amino Acid Substitution; Animals; Arginine; Corneal Dystrophies, Hereditary; Corneal Stroma; CRISPR-Cas Systems; Cysteine; Disease Models, Animal; Extracellular Matrix Proteins; Female; Heterozygote; Homozygote; Humans; Male; Mice; Mice, Transgenic; Microscopy, Electron, Transmission; Mutation; Recombinational DNA Repair; Transforming Growth Factor beta

2020
Cysteine-rich domain of type III collagen N-propeptide inhibits fibroblast activation by attenuating TGFβ signaling.
    Matrix biology : journal of the International Society for Matrix Biology, 2022, Volume: 109

    Topics: Actins; Breast Neoplasms; Cells, Cultured; Cicatrix; Collagen; Collagen Type III; Cysteine; Female; Fibroblasts; Humans; Myofibroblasts; Transforming Growth Factor beta; Tumor Microenvironment

2022
Biotin alleviates hepatic and intestinal inflammation and apoptosis induced by high dietary carbohydrate in juvenile turbot (Scophthalmus maximus L.).
    Fish & shellfish immunology, 2022, Volume: 130

    Topics: Animal Feed; Animals; Apoptosis; bcl-2-Associated X Protein; Biotin; Caspase 3; Cysteine; Diet; Dietary Carbohydrates; Dietary Supplements; Flatfishes; Inflammation; Interleukin-10; Interleukin-1beta; Interleukin-6; Interleukin-8; Liver; NF-kappa B; RNA, Messenger; Transforming Growth Factor beta; Transforming Growth Factors; Tumor Necrosis Factor-alpha

2022
Activating transcription factor 3 inhibits angiotensin II‑induced cardiomyocyte viability and fibrosis by activating the transcription of cysteine‑rich angiogenic protein 61.
    Molecular medicine reports, 2022, Volume: 26, Issue:5

    Topics: Activating Transcription Factor 3; Angiogenic Proteins; Angiotensin II; Cyclic AMP Response Element-Binding Protein; Cysteine; Cysteine-Rich Protein 61; Fibrosis; Humans; Myocytes, Cardiac; RNA, Messenger; Transforming Growth Factor beta

2022
Computational analysis of prodomain cysteines in human TGF-β proteins reveals frequent loss of disulfide-dependent regulation in tumors.
    G3 (Bethesda, Md.), 2022, 12-01, Volume: 12, Issue:12

    Topics: Cysteine; Disulfides; Humans; Neoplasms; Protein Binding; Transforming Growth Factor beta

2022