cysteine has been researched along with transforming growth factor beta in 65 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 1 (1.54) | 18.7374 |
1990's | 23 (35.38) | 18.2507 |
2000's | 28 (43.08) | 29.6817 |
2010's | 7 (10.77) | 24.3611 |
2020's | 6 (9.23) | 2.80 |
Authors | Studies |
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Das, SK; Fanburg, BL; White, AC | 1 |
Brunner, AM; Cook, J; Lioubin, MN; Madisen, L; Malacko, AR; Marquardt, H; Neubauer, M; Purchio, AF; Shapiro, RA; Wang, WC | 1 |
Dodge, GR; Hassell, JR; Iozzo, RV; Kovalszky, I | 1 |
Danielpour, D; Joyce, ME; Morales, TI; Roberts, AB; Sobel, ME | 1 |
Brunner, AM; Lioubin, MN; Malacko, AR; Marquardt, H; Purchio, AF | 1 |
Crookston, KP; Gonias, SL | 1 |
Bickenbach, JR; Bundman, D; Krieg, T; Longley, MA; Roberts, AB; Roche, NS; Roop, DR; Rothnagel, JA; Sellheyer, K | 1 |
Factor, V; Kondaiah, P; Kopp, J; Nagy, P; Roberts, AB; Sanderson, N; Sporn, MB; Thorgeirsson, SS; Wakefield, L | 1 |
Amatayakul-Chantler, S; Böttinger, EP; Gakenheimer, K; Qian, SW; Roberts, AB; Sporn, MB | 1 |
Atzori, L; Dypbukt, JM; Grafström, RC; Hybbinette, SS; Moldéus, P | 1 |
Homandberg, GA; Hui, F; Meyers, R; Xie, DL | 1 |
Bonadio, J; D'Alessio, M; Lynch, JR; Pangilinan, T; Pereira, L; Ramirez, F; Sykes, B | 1 |
Lee, SJ; McPherron, AC | 1 |
Grütter, MG; Schlunegger, MP | 1 |
Fujii, H; Hamada, H; Ikeda, M; Meno, C; Saijoh, Y; Toyoda, Y; Yokoyama, M; Yokoyama, T | 1 |
Keski-Oja, J; Saharinen, J; Taipale, J | 1 |
Beavis, RC; Gleizes, PE; Mazzieri, R; Rifkin, DB; Shen, B | 1 |
Haniu, M; Hui, J; Katta, V; Le, J; Lee, R; Rohde, MF; Shimamoto, G; Young, Y | 1 |
George, S; Hansen, CS; Marion, CD; Smith, WC; Steele, K | 1 |
Damji, KF; Guernsey, DL; Gupta, SK; Hodge, WG; Neumann, PE | 1 |
Bonadio, J; Fang, J; Smiley, E; Yin, W | 1 |
Keene, DR; Oganesian, A; Sandell, LJ; Zhu, Y | 1 |
Bernabéu, C; Calés, C; Langa, C; Lastres, P; Letamendía, A; López-Bote, JP; Páez, E; Raab, U; Tapia, E; Velasco, B | 1 |
Fanburg, BL; Lanzillo, JJ; Lee, SL; Maloney, EK; White, AC | 1 |
Cadene, M; Downing, AK; Dwek, RA; Gleizes, PE; Harvey, DJ; Rifkin, DB; Rudd, PM; Weir, I; Wormald, MR | 1 |
Keski-Oja, J; Saharinen, J | 1 |
Blair, SS; Conley, CA; Gelbart, W; Olson, DJ; Ralston, A; Rohwer-Nutter, D; Silburn, R; Singer, MA | 1 |
Sule, SD; Wigley, FM | 1 |
Kärkkäinen, M; Keski-Oja, J; Koli, K; Saharinen, J | 1 |
Chen, NC; Chen, SM; Pu, Q; Zhang, B; Zhu, BF | 1 |
Berry, C; Kambadur, R; Langley, B; Sharma, M; Thomas, M | 1 |
Annes, JP; Chen, Y; Dabovic, B; Rifkin, DB | 1 |
Waring, RH; Wilkinson, LJ | 1 |
Burmester, JK; Polga, D; Salzman, SA; Zhang, KQ | 1 |
Birk, DE; Carlson, EC; Funderburgh, JL; Gendron, RL; Kao, WW; Liu, CY; Mamiya, K | 1 |
Asundi, V; Binnerts, ME; Boyle, B; Bright, J; Canté-Barrett, K; Chen, HT; Funk, W; Rupp, F; Sattari, P; Tang, T; Wen, X | 1 |
Almogy, N; Bernstein, J; Biton, S; Eshel, D; Oren, A; Rotman, G; Savitsky, K; Toporik, A | 1 |
Sun, PD; Zou, Z | 1 |
Deane, CM; Downing, AK; Hamilton, JM; O'Leary, JM; Sandell, LJ; Valeyev, NV | 1 |
Arvola, T; Isolauri, E; Laitinen, K; Lampi, AM; Moilanen, E; Ruuska, T | 1 |
Ali, T; Chen, Y; Kristina Downing, A; O'leary, JM; Rifkin, DB; Todorovic, V | 1 |
Sebti, SM; Wang, DA | 1 |
Blakytny, R; Brunner, G; Erkell, LJ | 1 |
Inoue, K; Kodai, S; Minamiyama, Y; Mizuguchi, S; Okada, S; Suehiro, S; Takemura, S; Tsukioka, T | 1 |
Chaubert, P; El Kochairi, I; Letovanec, I; Munier, FL; Schorderet, DF; Uffer, S | 1 |
Kinoshita, T; Miyake, H; Nakajima, H; Ohori, M; Warizaya, M; Yoshimura, S | 1 |
Ha, H; Jung, H; Seong, HA | 1 |
Izumo, T; Kondo, M; Nagai, A | 1 |
Jones, DP; Ramadan, B; Ramirez, A; Ritzenthaler, JD; Rivera, HN; Roman, J | 1 |
Bonin, M; Kautzmann, S; Krüger, R; Marx, FP; Riess, O | 1 |
Diaz, JM; Herrera, L; Romero, MP; Romero, P; Vogel, M | 1 |
Gong, QH; Liu, Z; Wang, YQ; Xie, LX | 1 |
Darwiche, H; Oh, SH; Petersen, BE; Pintilie, DG; Salganik, SV; Shupe, TD | 1 |
Chang, SH; Harocopos, GJ; Huang, AJ; Patel, DA; Thang, DH; Vora, SC | 1 |
Mueller, TD; Nickel, J | 1 |
Chen, H; Fu, S; Geng, J; Jiang, Y; Jin, Y; Liu, D; Meng, X; Qu, H; Tong, D; Ye, S | 1 |
Maruyama, N; Ozawa, K; Takaiwa, F; Wakasa, Y; Yang, L | 1 |
Burke, TJ; Ritzenthaler, JD; Roman, J; Torres-González, E; Watson, WH; Zelko, IN | 1 |
Choi, SY; Choy, YB; Han, SM; Heo, CY; Kim, BH; Lee, SH; Park, CG; Park, HJ; Park, M | 1 |
Newfeld, SJ; Wisotzkey, RG | 1 |
Fujii, W; Inamochi, A; Kitamoto, K; Kuroda, M; Miyai, T; Ouchi, Y; Taketani, Y; Toyono, T; Usui, T; Yamagami, S | 1 |
Adams, SL; Brisson, BK; Burgwin, C; Chenoweth, D; Stewart, DC; Volk, SW; Wells, RG | 1 |
Huang, D; Li, X; Liu, D; Liu, J; Liu, Y; Luo, K; Mai, K; Pan, M; Wu, Z; Zhang, W | 1 |
Huang, C; Luo, H; Luo, Y; Wu, H; Zhang, Y | 1 |
Daly, SM; Newfeld, SJ; Peraza, A | 1 |
2 review(s) available for cysteine and transforming growth factor beta
Article | Year |
---|---|
Novel therapy in the treatment of scleroderma.
Topics: Autoimmune Diseases; Bone Marrow Transplantation; Cysteine; Humans; Interferon-gamma; Nitric Oxide; Piperidines; Prostaglandins; Quinazolines; Quinazolinones; Relaxin; Scleroderma, Systemic; Tetracycline; Transforming Growth Factor beta; Tumor Necrosis Factor-alpha | 2001 |
Promiscuity and specificity in BMP receptor activation.
Topics: Animals; Bone Morphogenetic Protein Receptors; Cysteine; Epitopes; Homeostasis; Humans; Hydrogen Bonding; Ligands; Models, Biological; Models, Molecular; Molecular Conformation; Phylogeny; Protein Binding; Protein Interaction Mapping; Signal Transduction; Time Factors; Transforming Growth Factor beta | 2012 |
63 other study(ies) available for cysteine and transforming growth factor beta
Article | Year |
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Modulation of transforming growth factor-beta 1 antiproliferative effects on endothelial cells by cysteine, cystine, and N-acetylcysteine.
Topics: Acetylcysteine; Animals; Cattle; Cell Division; Cells, Cultured; Cysteine; Cystine; Endothelium, Vascular; Glutathione; Transforming Growth Factor beta; Tumor Cells, Cultured | 1992 |
Site-directed mutagenesis of glycosylation sites in the transforming growth factor-beta 1 (TGF beta 1) and TGF beta 2 (414) precursors and of cysteine residues within mature TGF beta 1: effects on secretion and bioactivity.
Topics: Amino Acid Sequence; Animals; Cell Division; Cell Line; CHO Cells; Cricetinae; Cysteine; Glycosylation; Mannosephosphates; Mutagenesis, Site-Directed; Protein Precursors; Recombinant Proteins; Restriction Mapping; Transfection; Transforming Growth Factor beta | 1992 |
Transforming growth factor beta alters the expression of heparan sulfate proteoglycan in human colon carcinoma cells.
Topics: Cell Line; Cell Nucleus; Chondroitin Sulfate Proteoglycans; Colonic Neoplasms; Cycloheximide; Cysteine; Dactinomycin; Heparan Sulfate Proteoglycans; Heparitin Sulfate; Humans; Kinetics; Molecular Weight; Poly A; RNA; RNA, Messenger; RNA, Neoplasm; Transcription, Genetic; Transforming Growth Factor beta | 1990 |
Transforming growth factor-beta in calf articular cartilage organ cultures: synthesis and distribution.
Topics: Animals; Blotting, Northern; Cartilage, Articular; Cattle; Cysteine; Glycosaminoglycans; Kinetics; Organ Culture Techniques; Proteoglycans; RNA; Time Factors; Transforming Growth Factor beta | 1991 |
Site-directed mutagenesis of cysteine residues in the pro region of the transforming growth factor beta 1 precursor. Expression and characterization of mutant proteins.
Topics: Animals; Bacterial Proteins; Base Sequence; Cell Line; Codon; Cysteine; DNA, Single-Stranded; Genes; Molecular Sequence Data; Mutation; Protein Biosynthesis; Protein Precursors; Proteins; RNA, Bacterial; Transfection; Transforming Growth Factor beta; Transforming Growth Factors | 1989 |
The role of cysteine-949 in the binding of transforming growth factor-beta 1 and transforming growth factor-beta 2 to alpha 2-macroglobulin.
Topics: alpha-Macroglobulins; Cysteine; Disulfides; Humans; In Vitro Techniques; Iodoacetamide; Kinetics; Transforming Growth Factor beta | 1994 |
Inhibition of skin development by overexpression of transforming growth factor beta 1 in the epidermis of transgenic mice.
Topics: Amino Acid Sequence; Animals; Animals, Newborn; Cysteine; DNA; Gene Expression; Immunohistochemistry; Introns; Mice; Mice, Transgenic; Microscopy, Electron; Mutagenesis, Site-Directed; Reference Values; RNA; Serine; Skin; Swine; Transforming Growth Factor beta | 1993 |
Hepatic expression of mature transforming growth factor beta 1 in transgenic mice results in multiple tissue lesions.
Topics: Animals; Apoptosis; Cell Division; Cells, Cultured; Codon; Crosses, Genetic; Cysteine; DNA, Complementary; Female; Gene Expression; Glomerulonephritis; Inflammation; Kidney; Liver; Liver Cirrhosis, Experimental; Male; Mice; Mice, Inbred C57BL; Mice, Inbred CBA; Mice, Transgenic; Mitosis; Mutagenesis, Site-Directed; Myocardium; Restriction Mapping; Serine; Swine; Transforming Growth Factor beta | 1995 |
[Ser77]transforming growth factor-beta 1. Selective biological activity and receptor binding in mink lung epithelial cells.
Topics: Animals; Biological Assay; Cell Line; CHO Cells; Cricetinae; Cysteine; Disulfides; In Vitro Techniques; Mice; Mink; Models, Molecular; Mutagenesis, Site-Directed; Protein Conformation; Receptors, Transforming Growth Factor beta; Recombinant Proteins; Serine; Structure-Activity Relationship; Transforming Growth Factor beta | 1994 |
Modifications of cellular thiols during growth and squamous differentiation of cultured human bronchial epithelial cells.
Topics: Antimetabolites; Bronchi; Buthionine Sulfoximine; Calcium; Cell Differentiation; Cell Division; Cells, Cultured; Cysteine; Cystine; Epithelial Cells; Epithelium; Glutathione; Humans; Maleates; Methionine Sulfoximine; Oxidation-Reduction; Serum Albumin, Bovine; Sulfhydryl Compounds; Transforming Growth Factor beta | 1994 |
Cartilage chondrolysis by fibronectin fragments is associated with release of several proteinases: stromelysin plays a major role in chondrolysis.
Topics: Animals; Blotting, Western; Cartilage, Articular; Cattle; Cells, Cultured; Cysteine; Enzyme Activation; Fibronectins; Gelatinases; Humans; Insulin-Like Growth Factor I; Interferon-gamma; Kinetics; Matrix Metalloproteinase 3; Metalloendopeptidases; Methionine; Peptide Fragments; Proteoglycans; Recombinant Proteins; Serine Endopeptidases; Sulfur Radioisotopes; Synovial Fluid; Time Factors; Transforming Growth Factor beta | 1994 |
Genomic organization of the sequence coding for fibrillin, the defective gene product in Marfan syndrome.
Topics: Amino Acid Sequence; Base Sequence; Carrier Proteins; Chromosome Mapping; Chromosomes, Fungal; Cloning, Molecular; Cysteine; DNA; Epidermal Growth Factor; Exons; Fibrillins; Gene Library; Genome, Human; Humans; Intracellular Signaling Peptides and Proteins; Latent TGF-beta Binding Proteins; Marfan Syndrome; Microfilament Proteins; Molecular Sequence Data; Repetitive Sequences, Nucleic Acid; Transforming Growth Factor beta | 1993 |
GDF-3 and GDF-9: two new members of the transforming growth factor-beta superfamily containing a novel pattern of cysteines.
Topics: Amino Acid Sequence; Animals; Base Sequence; Bone Morphogenetic Protein 15; Cysteine; DNA; Female; Growth Differentiation Factor 3; Growth Differentiation Factor 9; Growth Substances; Humans; Intercellular Signaling Peptides and Proteins; Male; Mice; Molecular Sequence Data; Multigene Family; Oligodeoxyribonucleotides; Organ Specificity; Polymerase Chain Reaction; RNA, Messenger; Sequence Homology, Amino Acid; Transforming Growth Factor beta; Xenopus | 1993 |
Refined crystal structure of human transforming growth factor beta 2 at 1.95 A resolution.
Topics: Amino Acid Sequence; Cysteine; Humans; Hydrogen Bonding; Ions; Models, Chemical; Molecular Sequence Data; Proline; Protein Conformation; Protein Structure, Secondary; Recombinant Proteins; Transforming Growth Factor beta; Water; X-Ray Diffraction | 1993 |
Left-right asymmetric expression of the TGF beta-family member lefty in mouse embryos.
Topics: 3T3 Cells; Amino Acid Sequence; Animals; Base Sequence; Chromosome Mapping; Cysteine; DNA; Embryo, Mammalian; Embryonic and Fetal Development; Left-Right Determination Factors; Mice; Mice, Inbred ICR; Molecular Sequence Data; Mutation; Transforming Growth Factor beta; Tumor Cells, Cultured | 1996 |
Association of the small latent transforming growth factor-beta with an eight cysteine repeat of its binding protein LTBP-1.
Topics: Amino Acid Sequence; Animals; Binding Sites; Carrier Proteins; Cell Line; Chlorocebus aethiops; CHO Cells; Cricetinae; Cysteine; Disulfides; Electrophoresis, Polyacrylamide Gel; Epidermal Growth Factor; Extracellular Matrix; Extracellular Matrix Proteins; Humans; Intracellular Signaling Peptides and Proteins; Kidney; Latent TGF-beta Binding Proteins; Models, Structural; Molecular Sequence Data; Polymerase Chain Reaction; Recombinant Proteins; Repetitive Sequences, Nucleic Acid; Transfection; Transforming Growth Factor beta | 1996 |
Identification and characterization of an eight-cysteine repeat of the latent transforming growth factor-beta binding protein-1 that mediates bonding to the latent transforming growth factor-beta1.
Topics: Animals; Carrier Proteins; Cell Line; CHO Cells; Cricetinae; Cysteine; Humans; Intracellular Signaling Peptides and Proteins; Latent TGF-beta Binding Proteins; Mutagenesis; Nucleopolyhedroviruses; Protein Binding; Recombinant Proteins; Sequence Deletion; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Spodoptera; Transforming Growth Factor beta | 1996 |
Glial cell line-derived neurotrophic factor: selective reduction of the intermolecular disulfide linkage and characterization of its disulfide structure.
Topics: Amino Acid Sequence; Cell Line; Cysteine; Dimerization; Disulfides; Glial Cell Line-Derived Neurotrophic Factor; Humans; Molecular Sequence Data; Molecular Structure; Nerve Growth Factors; Nerve Tissue Proteins; Neuroglia; Oxidation-Reduction; Peptide Fragments; Peptide Mapping; Recombinant Proteins; Transforming Growth Factor beta | 1996 |
Direct neural induction and selective inhibition of mesoderm and epidermis inducers by Xnr3.
Topics: Amino Acid Sequence; Animals; Conserved Sequence; Cysteine; Ectoderm; Embryo, Nonmammalian; Embryonic Induction; Epidermis; Female; Gastrula; Gene Expression Regulation, Developmental; Mesoderm; Mice; Mutagenesis, Site-Directed; Nervous System; Organ Culture Techniques; Receptors, Transforming Growth Factor beta; Recombinant Proteins; Transforming Growth Factor beta; Xenopus; Xenopus Proteins | 1997 |
Lattice corneal dystrophy type 1 in a Canadian kindred is associated with the Arg124 --> Cys mutation in the kerato-epithelin gene. sgupta@ogh.on.ca.
Topics: Arginine; Canada; Chromosomes, Human, Pair 5; Corneal Dystrophies, Hereditary; Cysteine; DNA; DNA Primers; Extracellular Matrix Proteins; Female; Humans; Male; Neoplasm Proteins; Pedigree; Point Mutation; Polymerase Chain Reaction; Polymorphism, Single-Stranded Conformational; Transforming Growth Factor beta | 1998 |
8-Cysteine TGF-BP structural motifs are the site of covalent binding between mouse LTBP-3, LTBP-2, and latent TGF-beta 1.
Topics: Adaptor Proteins, Signal Transducing; Animals; Binding Sites; Carrier Proteins; Cysteine; Latent TGF-beta Binding Proteins; Mice; Protein Binding; Transforming Growth Factor beta | 1998 |
Type IIA procollagen containing the cysteine-rich amino propeptide is deposited in the extracellular matrix of prechondrogenic tissue and binds to TGF-beta1 and BMP-2.
Topics: Base Sequence; Bone Morphogenetic Protein 2; Bone Morphogenetic Proteins; Cartilage; Cysteine; DNA Primers; Extracellular Matrix; Fluorescent Antibody Technique; Humans; Microscopy, Immunoelectron; Procollagen; Protein Binding; Protein Isoforms; Recombinant Proteins; Transforming Growth Factor beta | 1999 |
Expression of normal and truncated forms of human endoglin.
Topics: Animals; Antigens, CD; Cell Line; Cell Membrane; Cysteine; Dimerization; Disulfides; Endoglin; Endothelium, Vascular; Gene Expression; Humans; Peptide Fragments; Protein Binding; Protein Isoforms; Receptors, Cell Surface; Recombinant Fusion Proteins; Reducing Agents; RNA, Messenger; Sequence Deletion; Solubility; Telangiectasia, Hereditary Hemorrhagic; Transfection; Transforming Growth Factor beta; Vaccinia virus; Vascular Cell Adhesion Molecule-1 | 1999 |
Reduction of endothelial cell related TGFbeta activity by thiols.
Topics: Acetylcysteine; Animals; Cattle; Cells, Cultured; Culture Media, Conditioned; Cysteine; Dose-Response Relationship, Drug; Endothelium, Vascular; Glutathione; Glutathione Disulfide; Oxidation-Reduction; Pulmonary Artery; Sulfhydryl Compounds; Swine; Transforming Growth Factor beta | 1999 |
Hybrid and complex glycans are linked to the conserved N-glycosylation site of the third eight-cysteine domain of LTBP-1 in insect cells.
Topics: Amino Acid Sequence; Animals; Baculoviridae; Carbohydrate Conformation; Carrier Proteins; Cell Line; Chromatography, High Pressure Liquid; Conserved Sequence; Cysteine; Glycosylation; Humans; Intracellular Signaling Peptides and Proteins; Latent TGF-beta Binding Proteins; Molecular Sequence Data; Oligosaccharides; Peptide Fragments; Polysaccharides; Protein Structure, Tertiary; Recombinant Fusion Proteins; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Spodoptera; Transforming Growth Factor beta | 2000 |
Specific sequence motif of 8-Cys repeats of TGF-beta binding proteins, LTBPs, creates a hydrophobic interaction surface for binding of small latent TGF-beta.
Topics: Amino Acid Motifs; Amino Acid Sequence; Carrier Proteins; Cysteine; Epithelial Cells; Fibrillins; Fibroblasts; Humans; Intracellular Signaling Peptides and Proteins; Latent TGF-beta Binding Proteins; Microfilament Proteins; Models, Molecular; Molecular Sequence Data; Protein Binding; Protein Isoforms; Protein Structure, Tertiary; Recombinant Fusion Proteins; Sequence Alignment; Transfection; Transforming Growth Factor beta | 2000 |
Crossveinless 2 contains cysteine-rich domains and is required for high levels of BMP-like activity during the formation of the cross veins in Drosophila.
Topics: Alleles; Amino Acid Sequence; Animals; Base Sequence; Bone Morphogenetic Proteins; Cloning, Molecular; Cysteine; DNA-Binding Proteins; Drosophila melanogaster; Drosophila Proteins; Gene Expression Regulation, Developmental; Immunohistochemistry; In Situ Hybridization; Insect Proteins; Molecular Sequence Data; Mutation; Protein Structure, Tertiary; Sequence Homology, Amino Acid; Signal Transduction; Time Factors; Transcription Factors; Transforming Growth Factor beta; Veins; Wings, Animal | 2000 |
Novel non-TGF-beta-binding splice variant of LTBP-4 in human cells and tissues provides means to decrease TGF-beta deposition.
Topics: Adaptor Proteins, Signal Transducing; Alternative Splicing; Carrier Proteins; Cell Line, Transformed; Culture Media, Conditioned; Cysteine; DNA, Complementary; Fibroblasts; Gene Expression; Humans; Immunoblotting; Kidney; Latent TGF-beta Binding Proteins; Lung; Osteosarcoma; Phenotype; Repetitive Sequences, Amino Acid; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Skin; Transforming Growth Factor beta; Tumor Cells, Cultured; Umbilical Veins | 2001 |
[Bone-inducing activity of human bone morphogenetic protein-2 102 peptide].
Topics: Animals; Biological Assay; Bone Morphogenetic Protein 2; Bone Morphogenetic Proteins; Cysteine; Escherichia coli; Femur; Humans; Mice; Osteogenesis; Peptide Fragments; Point Mutation; Protein Engineering; Recombinant Proteins; Transforming Growth Factor beta | 2001 |
Single cysteine to tyrosine transition inactivates the growth inhibitory function of Piedmontese myostatin.
Topics: Amino Acid Substitution; Animals; Cattle; Cell Division; Cell Line; Cysteine; Growth Inhibitors; Muscles; Mutation; Myostatin; Reference Values; RNA Stability; RNA, Messenger; Transforming Growth Factor beta; Tyrosine | 2002 |
Latent TGF-beta binding protein-3 (LTBP-3) requires binding to TGF-beta for secretion.
Topics: Adaptor Proteins, Signal Transducing; Animals; Carrier Proteins; Cells, Cultured; Cysteine; Disulfides; Humans; Intracellular Signaling Peptides and Proteins; Latent TGF-beta Binding Proteins; Mice; Protein Binding; Recombinant Fusion Proteins; Transfection; Transforming Growth Factor beta | 2002 |
Cysteine dioxygenase: modulation of expression in human cell lines by cytokines and control of sulphate production.
Topics: Antineoplastic Agents; Arthritis, Rheumatoid; Cell Line; Cysteine; Cysteine Dioxygenase; Dioxygenases; Humans; Inflammation; Liver; Neurons; Oxygenases; Sulfates; Transforming Growth Factor beta; Tumor Necrosis Factor-alpha | 2002 |
Amino acids 67 and 68 of transforming growth factor-beta regulate binding to a glycosyl phosphatidyl inositol-linked membrane protein on vascular endothelial cells.
Topics: Amino Acid Sequence; Animals; Cattle; Cell Membrane; Cells, Cultured; CHO Cells; Cricetinae; Cross-Linking Reagents; Cysteine; Endothelium, Vascular; Isoleucine; Ligands; Models, Molecular; Molecular Sequence Data; Mutation; Plasmids; Protein Binding; Protein Structure, Secondary; Protein Structure, Tertiary; Recombinant Fusion Proteins; Sequence Homology, Amino Acid; Swine; Threonine; Transforming Growth Factor beta; Transforming Growth Factor beta1; Transforming Growth Factor beta2 | 2002 |
Role of Cys41 in the N-terminal domain of lumican in ex vivo collagen fibrillogenesis by cultured corneal stromal cells.
Topics: Amino Acid Sequence; Animals; Base Sequence; Cells, Cultured; Chondroitin Sulfate Proteoglycans; Corneal Stroma; Cysteine; Extracellular Matrix; Fibrillar Collagens; Keratan Sulfate; Lumican; Mice; Microscopy, Electron; Molecular Sequence Data; Mutation; Protein Structure, Tertiary; Transforming Growth Factor beta | 2003 |
Human Crossveinless-2 is a novel inhibitor of bone morphogenetic proteins.
Topics: Alkaline Phosphatase; Animals; Bone Morphogenetic Protein 2; Bone Morphogenetic Protein 4; Bone Morphogenetic Proteins; Cell Differentiation; Cell Division; Cell Line; Cells, Cultured; Cysteine; DNA, Complementary; Dose-Response Relationship, Drug; Drosophila; Drosophila Proteins; Glycoproteins; Humans; Intercellular Signaling Peptides and Proteins; Mice; Osteoblasts; Phenotype; Phosphorylation; Protein Structure, Tertiary; Recombinant Proteins; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Signal Transduction; Tissue Distribution; Transforming Growth Factor beta | 2004 |
hCHL2, a novel chordin-related gene, displays differential expression and complex alternative splicing in human tissues and during myoblast and osteoblast maturation.
Topics: Activins; Alternative Splicing; Amino Acid Sequence; Animals; Bone Morphogenetic Protein 2; Bone Morphogenetic Proteins; Carrier Proteins; Cell Differentiation; Cell Line; Cell Line, Tumor; Chlorocebus aethiops; Conserved Sequence; COS Cells; Cysteine; Evolution, Molecular; Extracellular Matrix Proteins; Female; Gene Expression Profiling; Humans; Inhibin-beta Subunits; Insulin; Male; Mice; Molecular Sequence Data; Myoblasts; Osteoblasts; Protein Binding; Protein Isoforms; Recombinant Proteins; Reverse Transcriptase Polymerase Chain Reaction; RNA; Sequence Homology, Amino Acid; Transforming Growth Factor beta | 2004 |
Overexpression of human transforming growth factor-beta1 using a recombinant CHO cell expression system.
Topics: Animals; Biochemistry; Blotting, Western; Cell Culture Techniques; Cell Line; CHO Cells; Cricetinae; Cysteine; Disulfides; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Enzyme-Linked Immunosorbent Assay; Histidine; Humans; Mass Spectrometry; Models, Biological; Plasmids; Protein Binding; Protein Sorting Signals; Rats; Recombinant Proteins; Serum Albumin; Transforming Growth Factor beta; Transforming Growth Factor beta1 | 2004 |
Solution structure and dynamics of a prototypical chordin-like cysteine-rich repeat (von Willebrand Factor type C module) from collagen IIA.
Topics: Algorithms; Amino Acid Sequence; Binding Sites; Collagen Type II; Cysteine; Cysteine-Rich Protein 61; Cytokines; Disulfides; Evolution, Molecular; Extracellular Matrix; Eye Proteins; Fibronectins; Glycoproteins; Humans; Immediate-Early Proteins; Intercellular Signaling Peptides and Proteins; Ligands; Magnetic Resonance Spectroscopy; Models, Molecular; Molecular Sequence Data; Nerve Tissue Proteins; Protein Binding; Protein Conformation; Protein Structure, Secondary; Protein Structure, Tertiary; Proteomics; Sequence Homology, Amino Acid; Software; Transforming Growth Factor beta; Transforming Growth Factor beta1; Vascular Endothelial Growth Factor A | 2004 |
Characterization of breast milk received by infants with gross blood in stools.
Topics: Blood; Breast Feeding; Colitis; Cysteine; Dinoprostone; Fatty Acids; Feces; Female; Humans; Hypersensitivity; Immunoglobulin E; Infant; Infant, Newborn; Leukotrienes; Lipids; Logistic Models; Male; Milk, Human; Transforming Growth Factor beta; Transforming Growth Factor beta2; Tumor Necrosis Factor-alpha | 2005 |
Amino acid requirements for formation of the TGF-beta-latent TGF-beta binding protein complexes.
Topics: Amino Acid Sequence; Amino Acids; Animals; Binding Sites; Cell Line; Cysteine; Disulfides; Fluorescence Resonance Energy Transfer; Humans; Intracellular Signaling Peptides and Proteins; Latent TGF-beta Binding Proteins; Macromolecular Substances; Models, Molecular; Molecular Sequence Data; Mutation; Protein Binding; Protein Isoforms; Protein Structure, Tertiary; Sequence Alignment; TNF Receptor-Associated Factor 3; Transforming Growth Factor beta | 2005 |
Palmitoylated cysteine 192 is required for RhoB tumor-suppressive and apoptotic activities.
Topics: Alanine; Amino Acid Sequence; Apoptosis; Blotting, Western; Cell Cycle Proteins; Cell Line; Cell Line, Tumor; Cell Proliferation; Coloring Agents; Cyclin-Dependent Kinase Inhibitor p21; Cysteine; DNA Primers; Genes, Tumor Suppressor; Glycine; Humans; In Situ Nick-End Labeling; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; Palmitic Acid; Promoter Regions, Genetic; Protein Biosynthesis; Protein Prenylation; rhoA GTP-Binding Protein; rhoB GTP-Binding Protein; Sequence Homology, Amino Acid; Serine; Tetrazolium Salts; Thiazoles; Transcription Factor AP-1; Transcription, Genetic; Transfection; Transforming Growth Factor beta | 2005 |
Inactivation of active and latent transforming growth factor beta by free thiols: potential redox regulation of biological action.
Topics: Bacitracin; Blotting, Western; Cysteine; Dimerization; Dithiothreitol; Dose-Response Relationship, Drug; Glutathione; Homocysteine; Humans; Oxidation-Reduction; Recombinant Proteins; Sulfhydryl Compounds; Temperature; Transforming Growth Factor beta | 2006 |
S-allyl cysteine attenuated CCl4-induced oxidative stress and pulmonary fibrosis in rats.
Topics: Animals; Bronchoalveolar Lavage Fluid; Carbon Tetrachloride; Cysteine; Enzyme Precursors; Glutathione; Hydroxyproline; Liver; Lung; Male; Matrix Metalloproteinase 9; Nitric Oxide; Nitric Oxide Synthase Type II; Oxidative Stress; Pulmonary Fibrosis; Rats; Rats, Wistar; Reactive Oxygen Species; Sulfhydryl Compounds; Transforming Growth Factor beta; Transforming Growth Factor beta1 | 2006 |
Systemic investigation of keratoepithelin deposits in TGFBI/BIGH3-related corneal dystrophy.
Topics: Aged; Arginine; Cornea; Corneal Dystrophies, Hereditary; Cysteine; DNA Mutational Analysis; Exons; Extracellular Matrix Proteins; Humans; Immunohistochemistry; Male; Pulmonary Disease, Chronic Obstructive; Tissue Distribution; Transforming Growth Factor beta | 2006 |
Role of a cysteine residue in the active site of ERK and the MAPKK family.
Topics: Amino Acid Sequence; Animals; Binding Sites; Cells, Cultured; Cysteine; Humans; Lactones; MAP Kinase Kinase 1; MAP Kinase Kinase 7; Mink; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase Kinases; p38 Mitogen-Activated Protein Kinases; Sequence Alignment; Transcription Factor AP-1; Transforming Growth Factor beta | 2007 |
NM23-H1 tumor suppressor physically interacts with serine-threonine kinase receptor-associated protein, a transforming growth factor-beta (TGF-beta) receptor-interacting protein, and negatively regulates TGF-beta signaling.
Topics: Active Transport, Cell Nucleus; Apoptosis; Cell Nucleus; Cell Separation; Cysteine; Gene Expression Regulation, Neoplastic; HeLa Cells; Humans; Mutation; Neoplasm Proteins; NM23 Nucleoside Diphosphate Kinases; Nucleoside-Diphosphate Kinase; Protein Binding; Protein Structure, Tertiary; Recombinant Proteins; RNA-Binding Proteins; Transforming Growth Factor beta | 2007 |
Cysteinyl-leukotriene 1 receptor antagonist attenuates bleomycin-induced pulmonary fibrosis in mice.
Topics: Animals; Bleomycin; Bronchoalveolar Lavage Fluid; Cysteine; Disease Models, Animal; Hydroxyproline; Leukotriene Antagonists; Leukotrienes; Male; Mice; Mice, Inbred C57BL; Pulmonary Fibrosis; Receptors, Leukotriene; Transforming Growth Factor beta | 2007 |
Extracellular cysteine/cystine redox potential controls lung fibroblast proliferation and matrix expression through upregulation of transforming growth factor-beta.
Topics: Animals; Cell Proliferation; Cyclic AMP Response Element-Binding Protein; Cysteine; Cystine; Enzyme Activation; Extracellular Fluid; Fibroblasts; Fibronectins; Lung; Mice; NF-kappa B; NIH 3T3 Cells; Oxidation-Reduction; Phosphorylation; Protein Kinase C; RNA, Messenger; Signal Transduction; Smad3 Protein; Transforming Growth Factor beta; Up-Regulation | 2007 |
Microarray expression analysis reveals genetic pathways implicated in C621 synphilin-1-mediated toxicity.
Topics: Arginine; Carrier Proteins; Cell Line, Transformed; Cysteine; Gene Expression Regulation; Green Fluorescent Proteins; Humans; Mutation; Nerve Tissue Proteins; Oligonucleotide Array Sequence Analysis; Signal Transduction; Transfection; Transforming Growth Factor beta | 2008 |
Anticipation in familial lattice corneal dystrophy type I with R124C mutation in the TGFBI (BIGH3) gene.
Topics: Adolescent; Adult; Aged; Amino Acid Sequence; Amino Acid Substitution; Arginine; Base Sequence; Child; Child, Preschool; Cornea; Corneal Dystrophies, Hereditary; Cysteine; DNA Mutational Analysis; Extracellular Matrix Proteins; Female; Humans; Male; Molecular Sequence Data; Mutation; Pedigree; Phenotype; Transforming Growth Factor beta | 2008 |
An R124C mutation in TGFBI caused lattice corneal dystrophy type I with a variable phenotype in three Chinese families.
Topics: Adolescent; Adult; Amino Acid Substitution; Arginine; Asian People; Base Sequence; China; Corneal Dystrophies, Hereditary; Cysteine; DNA Mutational Analysis; Extracellular Matrix Proteins; Family; Female; Humans; Male; Molecular Sequence Data; Mutation; Pedigree; Phenotype; Transforming Growth Factor beta | 2008 |
Hepatic stellate cells' involvement in progenitor-mediated liver regeneration.
Topics: 2-Acetylaminofluorene; alpha-Fetoproteins; Animals; Connective Tissue Growth Factor; Cysteine; Hepatectomy; Hepatic Stellate Cells; Liver; Liver Diseases; Liver Regeneration; Male; Rats; Rats, Inbred F344; Stem Cells; Transforming Growth Factor beta | 2010 |
Granular and lattice deposits in corneal dystrophy caused by R124C mutation of TGFBIp.
Topics: Adult; Amyloid; Antibody Specificity; Arginine; Benzothiazoles; Cornea; Corneal Dystrophies, Hereditary; Corneal Stroma; Cysteine; Extracellular Matrix Proteins; Fluorescent Antibody Technique; Fluorescent Dyes; Genotype; Heterozygote; Humans; Male; Mutation; Penetrance; Staining and Labeling; Thiazoles; Transforming Growth Factor beta | 2010 |
S-allylmercaptocysteine promotes MAPK inhibitor-induced apoptosis by activating the TGF-β signaling pathway in cancer cells.
Topics: Apoptosis; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Proliferation; Cysteine; Drug Synergism; Gene Expression Regulation, Neoplastic; Hep G2 Cells; Humans; Liver Neoplasms; Protein Kinase Inhibitors; Signal Transduction; Transforming Growth Factor beta | 2014 |
Deposition mode of transforming growth factor-β expressed in transgenic rice seed.
Topics: Animals; Cysteine; Endosperm; Gene Expression Regulation, Plant; Intracellular Space; Mice; Oryza; Pepsin A; Plants, Genetically Modified; Prolamins; Protein Multimerization; Recombinant Proteins; Seeds; Transforming Growth Factor beta; Unfolded Protein Response | 2016 |
Differential Regulation of the Extracellular Cysteine/Cystine Redox State (EhCySS) by Lung Fibroblasts from Young and Old Mice.
Topics: Actins; Aging; Animals; Cells, Cultured; Cysteine; Cystine; Fibroblasts; Fibronectins; Lung; Mice; Oxidation-Reduction; Superoxide Dismutase; Transforming Growth Factor beta | 2016 |
Prolonged, acute suppression of cysteinyl leukotriene to reduce capsular contracture around silicone implants.
Topics: Adipose Tissue; Animals; Collagen; Cysteine; Female; Fibroblasts; Implants, Experimental; Inflammation; Lactic Acid; Leukotrienes; Macrophages; Microscopy, Electron, Scanning; Myofibroblasts; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Rats; Rats, Sprague-Dawley; Silicones; Transforming Growth Factor beta | 2017 |
TGF-β Prodomain Alignments Reveal Unexpected Cysteine Conservation Consistent with Phylogenetic Predictions of Cross-Subfamily Heterodimerization.
Topics: Amino Acid Sequence; Animals; Caenorhabditis elegans; Cysteine; Drosophila melanogaster; Evolution, Molecular; Humans; Mice; Phylogeny; Protein Binding; Protein Domains; Sequence Alignment; Signal Transduction; Transforming Growth Factor beta | 2020 |
Generation of mouse model of TGFBI-R124C corneal dystrophy using CRISPR/Cas9-mediated homology-directed repair.
Topics: Amino Acid Substitution; Animals; Arginine; Corneal Dystrophies, Hereditary; Corneal Stroma; CRISPR-Cas Systems; Cysteine; Disease Models, Animal; Extracellular Matrix Proteins; Female; Heterozygote; Homozygote; Humans; Male; Mice; Mice, Transgenic; Microscopy, Electron, Transmission; Mutation; Recombinational DNA Repair; Transforming Growth Factor beta | 2020 |
Cysteine-rich domain of type III collagen N-propeptide inhibits fibroblast activation by attenuating TGFβ signaling.
Topics: Actins; Breast Neoplasms; Cells, Cultured; Cicatrix; Collagen; Collagen Type III; Cysteine; Female; Fibroblasts; Humans; Myofibroblasts; Transforming Growth Factor beta; Tumor Microenvironment | 2022 |
Biotin alleviates hepatic and intestinal inflammation and apoptosis induced by high dietary carbohydrate in juvenile turbot (Scophthalmus maximus L.).
Topics: Animal Feed; Animals; Apoptosis; bcl-2-Associated X Protein; Biotin; Caspase 3; Cysteine; Diet; Dietary Carbohydrates; Dietary Supplements; Flatfishes; Inflammation; Interleukin-10; Interleukin-1beta; Interleukin-6; Interleukin-8; Liver; NF-kappa B; RNA, Messenger; Transforming Growth Factor beta; Transforming Growth Factors; Tumor Necrosis Factor-alpha | 2022 |
Activating transcription factor 3 inhibits angiotensin II‑induced cardiomyocyte viability and fibrosis by activating the transcription of cysteine‑rich angiogenic protein 61.
Topics: Activating Transcription Factor 3; Angiogenic Proteins; Angiotensin II; Cyclic AMP Response Element-Binding Protein; Cysteine; Cysteine-Rich Protein 61; Fibrosis; Humans; Myocytes, Cardiac; RNA, Messenger; Transforming Growth Factor beta | 2022 |
Computational analysis of prodomain cysteines in human TGF-β proteins reveals frequent loss of disulfide-dependent regulation in tumors.
Topics: Cysteine; Disulfides; Humans; Neoplasms; Protein Binding; Transforming Growth Factor beta | 2022 |