cysteine and thiazolidines

cysteine has been researched along with thiazolidines in 151 studies

Research

Studies (151)

TimeframeStudies, this research(%)All Research%
pre-199031 (20.53)18.7374
1990's46 (30.46)18.2507
2000's20 (13.25)29.6817
2010's29 (19.21)24.3611
2020's25 (16.56)2.80

Authors

AuthorsStudies
Freedland, RA; Simpson, RC1
DeMaster, EG; Elberling, JA; Nagasawa, HT; Shirota, FN1
Banks, MF; Coloso, RM; Garcia, RA; Stipanuk, MH1
Charyulu, RL; Nagasawa, HT; Roberts, JC; Zera, RT1
Astre, C; Joyeux, H; Possompes, B; Recasens, MA; Saint Aubert, B1
Francetic, DJ; Roberts, JC1
Rommelspacher, H; Schühle, M; Susilo, R1
Francetic, DJ; Roberts, JC; Zera, RT1
Coloso, RM; Hirschberger, LL; Stipanuk, MH1
Fujimoto, M; Hirata, M; Ohno, K1
Aebi, S; Lauterburg, BH; Porta, P; Summer, K1
Baker, DH; Chung, TK; Funk, MA1
Ferko, AP1
Akagi, R; Taguchi, T; Ubuka, T1
Anderson, ME; Bridges, RJ; Meister, A; Underwood, M1
Anderson, ME; Meister, A2
Böhler, S1
DeGraff, WG; Mitchell, JB; Russo, A1
Kwapiszewski, W; Ryzewski, J1
Lang, CA; Richie, JP1
Bauman, PF; Bray, TM; Smith, TK1
Nishina, H; Ohta, J; Ubuka, T1
Fricke, RF; Goon, DJ; Nagasawa, HT; Roberts, JC; Zera, RT1
O'Neill, IK; Ohshima, H1
Anderson, ME; Hwang, O; Meister, A1
Hazelton, GA; Hjelle, JJ; Klaassen, CD1
Buckthal, DJ; Burns, CL; Hamilton, GA; Main, DE1
Bruggink, JE; Glazenburg, EJ; Mulder, GJ; Wolters-Keulemans, K1
Czubak, J; Włodek, L1
Bartsch, H; Friesen, M; O'Neill, IK; Ohshima, H; Pignatelli, B1
Bartsch, H; Friesen, M; O'Neill, I; Ohshima, H1
Hemminki, K1
Fleming, JF; Miquel, J; Weber, HU1
Boettcher, B; Meister, A; Williamson, JM1
Görler, K; Krumbiegel, G; Mennicke, WH; Siehl, HU1
Anders, MW; Stevens, JL1
Grabowska, A; Marcinkiewicz, J; Włodek, L1
Bubrick, MP; Carroll, MP; Feeney, DA; Johnston, GR; Roberts, JC; Schlafmann, SE; West, MA; Zera, RT1
Rommelspacher, H; Wlodek, L1
Abe, T; Kinuta, M; Ubuka, T; Yao, WB; Zhao, YQ1
Borum, PR; Chance, M; Emgushov, RT; Jackson, JB; Kalayjian, RC; Mayer, KH; Skowron, G; Spell, SA; Webb, LS; Yen-Lieberman, B1
Bais, R; Baker, PW; Rofe, AM3
Barnidge, M; Janney, CG; Neuschwander-Tetri, BA1
Grendell, JH; Luthen, RE1
Ensunsa, JL; Hirschberger, LL; Stipanuk, MH1
Bray, TM; Goss, PM; Nagy, LE1
Banks, MF; Stipanuk, MH1
Fujiyama, J; Hirayama, K; Yasutake, A1
Chaudiére, J; Fougeat, S; Gerard-Monnier, D; Gourvest, JF1
Bubrick, MP; Feeney, DA; Fink, AS; Johnston, GR; Madoff, RD; Roberts, JC; Rowe, JK; Young, HL; Zera, RT1
Glosson, JA; Goldberg, DI; Madsen, DC; Rowe, WB; White, RD; Wilson, DM1
Smith, TK; Sousadias, MG1
Baker, ER; Baker, H; DeAngelis, B; Frank, O; Hutner, SH; Khalil, M1
Arons, MM; Bernard, GR; Morris, PE; Paz, HL; Russell, JA; Wheeler, AP; Wright, PE1
Ali-Osman, F; Srivenugopal, KS1
Arstrand, K; Dizdar, N; Kågedal, B; Kullman, A1
Beani, JC; Emonet, N; Favier, A; Leccia, MT; Richard, MJ1
Dringen, R; Hamprecht, B; Kranich, O; Sandberg, M1
Frei, B; Gokce, N; Holbrook, M; Keaney, JF; Leaf, C; Vita, JA1
Harris, C; Miller, JM; Nuttall, AL; Raphael, Y; Yamasoba, T1
Rommelspacher, H; Włodek, L1
Barditch-Crovo, P; Borum, P; Buier, R; Goldberg, D; Kalayjian, RC; Lederman, M; Lietman, P; Noe, D; Rowe, WB; Skowron, G1
Alghamdi, GA; Borum, PR; Jassal, SV; Logan, J; Martis, L; Moberly, JB; Moran, JE; Mupas, L; Oreopoulos, DG; Rodela, H; Story, KO; Webb, LE; Wolfson, M1
Gwilt, PR; Leaf, CD; Li, XY; Radick, LE; Whalen, JJ1
Arakaki, R; Baba, M; Jinno, S; Nakashima, H; Premanathan, M; Ramanan, S; Yamashita, S1
Dringen, R; Hamprecht, B1
Ajami, AM; Fukagawa, NK; Hercules, E1
Dizdar, N; Kågedal, B; Kullman, A1
Hammarqvist, F; Wernerman, J1
Alonso-Varona, A; Bilbao, P; Calle, Y; Castro, B; del Olmo, M; Palomares, T1
Arduini, RM; Baker, DP; Boriack-Sjodin, A; Carmillo, AN; Day, ES; Galdes, A; Garber, EA; Hronowski, X; Pepinsky, RB; Rayhorn, P; Shapiro, RI; Taylor, FR; Weinreb, PH; Wen, D; Whitty, A; Williams, KP1
Cassidy, PB; Roberts, JC; Warters, RL; Wilmore, BH1
An, NH; Han, MK; Jang, SI; Kim, HK; Kim, SJ; Kim, UH; Park, HJ; Park, KH; Park, KJ; Park, YR; Shin, YM1
Assimos, DG; Holmes, RP; Milliner, DS; Wilson, DM1
Drozak, J; Winiarska, K1
Lenarczyk, M; Ueno, A; Vannais, D; Waldren, CA1
HARRIS, J; MACKENZIE, CG1
LUKENS, RJ; SISLER, HD1
EGER, W1
DEBEY, HJ; MACKENZIE, CG; MACKENZIE, JB1
HARUNA, H; HASHIMOTO, S; IZUMI, K; KATAYAMA, M; MATSUBAYASHI, Y; OGISO, A; OKUJIMA, J; SUZUKI, S; TAKANO, T1
EZAKI, H; FUNAOKA, H1
Hei, TK; Kraemer, S; Kronenberg, A; Lenarczyk, M; Roberts, JC; Tatsumi, K; Ueno, A; Vannais, DB; Waldren, CA1
Abe, K; Iijima, Y; Ishikawa, H; Watanabe, T1
Bang, D; Kent, SB1
Ueno, AM; Vannais, DB; Waldren, CA1
Cohen, SD; Dominick, PK; Roberts, JC; Slitt, AM1
Lee, YC; Park, SJ1
Chen, TS; Nagasawa, H; Oz, HS1
Bi, X; Hartono, D; Yang, KL1
Carmi, C; Fu, J; King, AR; Lodola, A; Mor, M; Piomelli, D1
Mahler, G; Manta, E; Saiz, C; Wipf, P1
Dayon, L; Giron, P; Mihala, N; Rose, K; Sanchez, JC1
MIDDLEBROOK, WR; PHILLIPS, H1
Jurkowska, H; Roberts, J; Uchacz, T; Wróbel, M1
Al Moutaery, M; Al Rayes, H; Al Swailam, R; Arshaduddin, M; Elfaki, I; Khan, HA; Tariq, M1
Lis, T; Slepokura, K; Tarnawski, M1
Dheur, J; Melnyk, O; Ollivier, N1
Moeller, R; Reitz, G; Setlow, P; Wassmann, M1
Amberg, DC; Farah, ME; Haarer, B; Kakhniashvili, D; Sirotkin, V1
Helms, BA; Lempens, EH; Merkx, M1
Kim, HJ; Shin, HS1
Im, GY; Kazi, S; Perumalswami, PV; Thung, SN1
Bernardes, GJ; Casi, G; Hartmann, I; Neri, D; Steiner, M1
Brunsveld, L; Ibach, J; Nieto, L; Sonntag, MH; Verveer, PJ1
Barve, A; Escobedo, JO; Hakuna, L; Huynh, KT; Lowry, M; Strongin, RM1
Chang, CY; Liu, SR; Wu, SP1
Jiménez, C; Montaos, MA; Rodríguez, J; Segade, Y1
De Nicola, A; Poirel, A; Ziessel, R1
Boll, E; Drobecq, H; Ebran, JP; El-Mahdi, O; Melnyk, O; Ollivier, N; Raibaut, L1
Saltman, AE1
Acar, ET; Akgün, H; Buran, K; Kahveci Ulugöl, R; Önen Bayram, FE; Sipahi, H1
Brik, A; Jbara, M; Maity, SK; Seenaiah, M1
Amara, P; Benjdia, A; Berteau, O; Favier, A; Fontecilla-Camps, JC; Martin, L; Mouesca, JM; Nicolet, Y; Rohac, R; Ruffié, P1
Amino, Y; Iwasaki, K; Kaneko, M; Kashiwagi, T; Ookura, F; Takino, Y; Yamamoto, M1
Cui, J; Hu, J; Nian, Y; Su, D; Wang, S; Yang, J; Zhang, F; Zhou, M1
Adeleke, O; Falana, B; Orenolu, M; Osinubi, A; Oyewopo, A1
Mase, N; Narumi, T; Sato, K; Tanaka, S; Tashiro, Y; Yamamoto, K1
Brik, A; Jbara, M; Kamnesky, G; Laps, S; Mann, G; Morgan, M; Wolberger, C1
Dalle Donne, I; Galvagni, F; Giustarini, D; Milzani, A; Rossi, R; Santucci, A; Severi, FM1
Mall, V; Schieberle, P; Sellami, I1
Callegari, E; Feng, S; Liu, Y; Mammenga, E; Min, JW; Qiao, F; Subedi, K; Wang, H1
Cui, H; Hayat, K; Ho, CT; Hussain, S; Jia, C; Tahir, MU; Yu, J; Zhai, Y; Zhang, X1
Ajayi, AM; Ben-Azu, B; Emokpae, O; Umukoro, S2
Bar-Even, A; Bruner, SD; Fiehn, O; Folz, JS; Hanson, AD; He, H; Li, Q; Patterson, JA; Wilson, MA1
Gao, J; Li, K; Wang, W1
Głowacka, IE; Głowacki, R; Piechocka, J; Wrońska, M1
Chan, HW; Chan, W; Ham, YH; Pan, G; Yao, J1
Cui, H; Deng, S; Hayat, K; Ho, CT; Hussain, S; Tahir, MU; Zhai, Y; Zhang, Q; Zhang, X1
Ajayi, AM; Akinluyi, ET; Ben-Azu, B; Emokpae, O; Okoh, L; Umukoro, S1
Brik, A; Glickman, MH; Mann, G; Satish, G; Sulkshane, P; Vamisetti, GB1
Afolayan, OO; Agie, JA; Fidelis, OP; Ogunlade, B1
Gbotolorun, SC; Ogunlade, AA; Ogunlade, B1
Afolayan, GO; Oludare, GO; Semidara, GG1
Adejumobi, OA; Adeyemi, WJ; Ajibade, TO; David, UE; Fasanmade, AA; Ojetola, AA; Omobowale, TO; Oyagbemi, AA1
Cui, H; Deng, S; Hayat, K; Ho, CT; Wu, X; Zhai, Y; Zhang, Q; Zhang, X1
Ajao, MS; Akingbade, GT; Aschner, M; Ijomone, OM; Imam, A1
Becker, DF; Patel, SM; Seravalli, J; Stiers, KM; Tanner, JJ1
Chen, H; Huo, S; Ma, D; Shen, S; Shi, T; Song, C; Sun, J; Wang, Y; Xu, W1
Agbonifo-Chijiokwu, E; Edesiri, TP; Faith, FY; Kingsley, NE; Mega, OO; Oghenetega, BO; Rume, RA; Simon, OI; Victor, E1
Hayashi, G; Murakami, H; Nakatsu, K; Okamoto, A1
Cui, H; Hayat, K; Ho, CT; Wei, S; Zhang, X1
Cavadas, RAN; Faustino, H; Gois, PMP; Silva, MJSA; Veiros, LF1
Chen, C; Krishna, V; Mulay, P1
Głowacki, R; Piechocka, J; Wyszczelska-Rokiel, M1
Chen, Y; Gu, Z; He, Y; Kong, D; Ma, S; Mao, H; Song, J; Xu, S; Yuan, M; Zhou, Y1
Brandsch, M; Gebauer, S; Laug, L; Schäfer, S; Thondorf, I; Voigt, V; Zebisch, K1

Reviews

4 review(s) available for cysteine and thiazolidines

ArticleYear
Thiazolidine-4-carboxylic acid, a physiologic sulfhydryl antioxidant with potential value in geriatric medicine.
    Archives of gerontology and geriatrics, 1982, Volume: 1, Issue:4

    Topics: Aged; Animals; Antioxidants; Chemical Phenomena; Chemistry; Cysteine; Dogs; Drug Combinations; Folic Acid; Gastrointestinal Diseases; Humans; Liver Diseases; Longevity; Mice; Rats; Thiazoles; Thiazolidines

1982
Modulation of endogenous glutathione availability.
    Current opinion in clinical nutrition and metabolic care, 1999, Volume: 2, Issue:6

    Topics: Acetylcysteine; Animals; Cysteine; Glutamine; Glutathione; Humans; Protein Precursors; Pyrrolidonecarboxylic Acid; Thiazoles; Thiazolidines

1999
[Glutathione in therapy].
    Postepy higieny i medycyny doswiadczalnej, 2002, Volume: 56, Issue:4

    Topics: Animals; Cysteine; Diabetes Mellitus; Glutathione; Humans; Infections; Neurodegenerative Diseases; Oxidative Stress; Pyrrolidonecarboxylic Acid; Thiazoles; Thiazolidines

2002
Antioxidants as novel agents for asthma.
    Mini reviews in medicinal chemistry, 2006, Volume: 6, Issue:2

    Topics: Acetylcysteine; Anti-Asthmatic Agents; Antioxidants; Asthma; Cysteine; Glutathione; Humans; Oxidative Stress; Pyrrolidonecarboxylic Acid; Reactive Oxygen Species; Thiazoles; Thiazolidines

2006

Trials

6 trial(s) available for cysteine and thiazolidines

ArticleYear
A phase I/II trial of intravenous L-2-oxothiazolidine-4-carboxylic acid (procysteine) in asymptomatic HIV-infected subjects.
    Journal of acquired immune deficiency syndromes, 1994, Volume: 7, Issue:4

    Topics: Adult; Aged; beta 2-Microglobulin; CD4-Positive T-Lymphocytes; Cysteine; Female; Glutathione; HIV Seropositivity; Humans; Infusions, Intravenous; Leukocyte Count; Male; Middle Aged; Pyrrolidonecarboxylic Acid; Thiazoles; Thiazolidines

1994
A trial of antioxidants N-acetylcysteine and procysteine in ARDS. The Antioxidant in ARDS Study Group.
    Chest, 1997, Volume: 112, Issue:1

    Topics: Acetylcysteine; Adult; Antioxidants; Bilirubin; Bronchoalveolar Lavage Fluid; Cardiac Output; Cysteine; Double-Blind Method; Free Radical Scavengers; Glutathione; Humans; Middle Aged; Prospective Studies; Pyrrolidonecarboxylic Acid; Respiration, Artificial; Respiratory Distress Syndrome; Thiazoles; Thiazolidines; Time Factors

1997
L-2-Oxothiazolidine-4-carboxylic acid reverses endothelial dysfunction in patients with coronary artery disease.
    The Journal of clinical investigation, 1998, Mar-15, Volume: 101, Issue:6

    Topics: Administration, Oral; Aged; Arteriosclerosis; Blood Flow Velocity; Blood Glucose; Blood Pressure; Cholesterol; Coronary Disease; Cysteine; Double-Blind Method; Endothelium, Vascular; Female; Glutathione; Heart Rate; Humans; Hyperemia; Male; Middle Aged; Nitric Oxide; Nitroglycerin; Oxidation-Reduction; Pyrrolidonecarboxylic Acid; Thiazoles; Thiazolidines; Triglycerides; Ultrasonography

1998
A phase I/II evaluation of oral L-2-oxothiazolidine-4-carboxylic acid in asymptomatic patients infected with human immunodeficiency virus.
    Journal of clinical pharmacology, 1998, Volume: 38, Issue:4

    Topics: Adult; Anti-HIV Agents; Cysteine; Dose-Response Relationship, Drug; Double-Blind Method; Glutathione; HIV Infections; Humans; Leukocytes, Mononuclear; Middle Aged; Prodrugs; Pyrrolidonecarboxylic Acid; Thiazoles; Thiazolidines

1998
Elevation of whole-blood glutathione in peritoneal dialysis patients by L-2-oxothiazolidine-4-carboxylate, a cysteine prodrug (Procysteine).
    Journal of the American Society of Nephrology : JASN, 1998, Volume: 9, Issue:6

    Topics: Administration, Oral; Cysteine; Double-Blind Method; Female; Glutathione; Humans; Kidney Failure, Chronic; Male; Middle Aged; Osmolar Concentration; Peritoneal Dialysis, Continuous Ambulatory; Prospective Studies; Pyrrolidonecarboxylic Acid; Thiazoles; Thiazolidines

1998
(L)-2-oxothiazolidine-4-carboxylate in the treatment of primary hyperoxaluria type 1.
    BJU international, 2001, Volume: 88, Issue:9

    Topics: Calcium Oxalate; Calcium, Dietary; Cysteine; Female; Humans; Hyperoxaluria, Primary; Infusions, Intravenous; Male; Middle Aged; Pyrrolidonecarboxylic Acid; Thiazoles; Thiazolidines; Treatment Outcome

2001

Other Studies

141 other study(ies) available for cysteine and thiazolidines

ArticleYear
The isolation and identification of 2-methyl-2,4-thiazolidine dicarboxylate as a by-product in the conversion of cysteine to glucose in the perfused rat liver.
    Biochimica et biophysica acta, 1977, Jan-24, Volume: 496, Issue:1

    Topics: Animals; Chemical Phenomena; Chemistry; Cysteine; Dicarboxylic Acids; Dietary Proteins; Gluconeogenesis; Kidney; Lactates; Liver; Male; Pyruvates; Rats; Thiazoles; Thiazolidines

1977
Failure of glutathione and cysteine prodrugs to block the chlorpropamide-induced inhibition of aldehyde dehydrogenase in vivo.
    Biochemical pharmacology, 1992, Feb-18, Volume: 43, Issue:4

    Topics: Acetaldehyde; Aldehyde Dehydrogenase; Animals; Chlorpropamide; Cysteine; Ethanol; Glutathione; Male; Prodrugs; Rats; Rats, Inbred Strains; Thiazoles; Thiazolidines

1992
Cysteine concentration regulates cysteine metabolism to glutathione, sulfate and taurine in rat hepatocytes.
    The Journal of nutrition, 1992, Volume: 122, Issue:3

    Topics: Animals; Cells, Cultured; Chelating Agents; Cysteine; Glutathione; Indicators and Reagents; Liver; Male; Methionine; Phenanthrolines; Pyrrolidonecarboxylic Acid; Rats; Rats, Inbred Strains; Sulfates; Taurine; Thiazoles; Thiazolidines

1992
Protection against acetaminophen hepatotoxicity by ribose-cysteine (RibCys).
    Pharmacology & toxicology, 1992, Volume: 70, Issue:4

    Topics: Acetaminophen; Animals; Antidotes; Chemical and Drug Induced Liver Injury; Cysteine; Dose-Response Relationship, Drug; Drug Administration Routes; Drug Administration Schedule; Male; Mice; Prodrugs; Thiazoles; Thiazolidines

1992
Thiazolidine-4-carboxylate and 2-phenylthiazolidine-4-carboxylate are active as cysteine precursors but have no effect on growth of a methionine-dependent tumor in rats.
    The Journal of nutrition, 1992, Volume: 122, Issue:1

    Topics: Amino Acids; Animals; Antineoplastic Agents; Body Weight; Cysteine; Glutathione; Male; Methionine; Rats; Rats, Inbred Strains; Rhabdomyosarcoma; Thiazoles; Thiazolidines

1992
Time course for the elevation of glutathione in numerous organs of L1210-bearing CDF1 mice given the L-cysteine prodrug, RibCys.
    Toxicology letters, 1991, Volume: 59, Issue:1-3

    Topics: Animals; Cysteine; Glutathione; Injections, Intraperitoneal; Leukemia L1210; Liver; Male; Mice; Prodrugs; Thiazoles; Thiazolidines

1991
Detection of a new intermediate product of indolealkylamine metabolism in the brain.
    Advances in experimental medicine and biology, 1991, Volume: 294

    Topics: Animals; Brain Chemistry; Cattle; Cysteine; Indoles; Rats; Swine; Thiazoles; Thiazolidines

1991
L-cysteine prodrug protects against cyclophosphamide urotoxicity without compromising therapeutic activity.
    Cancer chemotherapy and pharmacology, 1991, Volume: 28, Issue:3

    Topics: Animals; Cyclophosphamide; Cysteine; Dose-Response Relationship, Drug; Drug Interactions; Drug Screening Assays, Antitumor; Glutathione; Leukemia L1210; Male; Mice; Mice, Inbred Strains; Neoplasm Transplantation; Prodrugs; Thiazoles; Thiazolidines; Time Factors; Urinary Bladder

1991
Uptake and metabolism of L-2-oxo-[35S]thiazolidine-4-carboxylate by rat cells is slower than that of L-[35S]cysteine or L-[35S]methionine.
    The Journal of nutrition, 1991, Volume: 121, Issue:9

    Topics: Animals; Biological Transport; Chromatography, High Pressure Liquid; Cysteine; Glutathione; In Vitro Techniques; Intestine, Small; Kidney Tubules; Liver; Male; Methionine; Pyrrolidonecarboxylic Acid; Rats; Rats, Inbred Strains; Sulfur Radioisotopes; Thiazoles; Thiazolidines

1991
Protective effect of prostaglandin A2 against menadione-induced cell injury in cultured porcine aorta endothelial cells.
    Chemico-biological interactions, 1991, Volume: 78, Issue:1

    Topics: Animals; Aorta; Cells, Cultured; Cysteine; Dose-Response Relationship, Drug; Endothelium, Vascular; Glutathione; Methionine; Prostaglandins A; Pyrrolidonecarboxylic Acid; Swine; Thiazoles; Thiazolidines; Time Factors; Vitamin K

1991
L-2-oxothiazolidine-4-carboxylic acid, a cysteine prodrug: pharmacokinetics and effects on thiols in plasma and lymphocytes in human.
    The Journal of pharmacology and experimental therapeutics, 1991, Volume: 257, Issue:1

    Topics: Adult; Cysteine; Glutathione; Humans; Lymphocytes; Male; Middle Aged; Prodrugs; Pyrrolidonecarboxylic Acid; Thiazoles; Thiazolidines

1991
L-2-oxothiazolidine-4-carboxylate as a cysteine precursor: efficacy for growth and hepatic glutathione synthesis in chicks and rats.
    The Journal of nutrition, 1990, Volume: 120, Issue:2

    Topics: Administration, Oral; Animals; Chickens; Cysteine; Diet; Glutathione; Liver; Male; Pyrrolidonecarboxylic Acid; Random Allocation; Rats; Rats, Inbred Strains; Regression Analysis; Thiazoles; Thiazolidines; Weight Gain

1990
The interaction between ethanol and cysteine on the central depressant effects of ethanol in mice.
    Pharmacology, biochemistry, and behavior, 1990, Volume: 36, Issue:3

    Topics: Animals; Cysteine; Drug Synergism; Ethanol; gamma-Aminobutyric Acid; Injections, Intraventricular; Isethionic Acid; Male; Mice; Posture; Pyrrolidonecarboxylic Acid; Reflex; Thiazoles; Thiazolidines

1990
Tissue contents and urinary excretion of taurine after administration of L-cysteine and L-2-oxothiazolidine-4-carboxylate to rats.
    Acta medica Okayama, 1990, Volume: 44, Issue:3

    Topics: Animals; Caseins; Cysteine; Cysteine Dioxygenase; Cystine; Dietary Proteins; Dioxygenases; Injections, Intraperitoneal; Liver; Male; Oxygenases; Pyrrolidonecarboxylic Acid; Rats; Rats, Inbred Strains; Taurine; Thiazoles; Thiazolidines; Tissue Distribution

1990
Glutathione metabolism at the blood-cerebrospinal fluid barrier.
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 1989, Volume: 3, Issue:13

    Topics: Animals; Antimetabolites; Biological Transport; Blood-Brain Barrier; Buthionine Sulfoximine; Choroid Plexus; Cysteine; Dipeptides; gamma-Glutamyltransferase; Glutathione; Isoxazoles; Male; Methionine Sulfoximine; Pyrrolidonecarboxylic Acid; Rats; Rats, Inbred Strains; Thiazoles; Thiazolidines

1989
Marked increase of cysteine levels in many regions of the brain after administration of 2-oxothiazolidine-4-carboxylate.
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 1989, Volume: 3, Issue:5

    Topics: Animals; Brain; Brain Stem; Caudate Nucleus; Cerebellum; Cerebral Cortex; Cysteine; Glutathione; Hypothalamus; Male; Mice; Pons; Pyrrolidonecarboxylic Acid; Rats; Rats, Inbred Strains; Thiazoles; Thiazolidines

1989
[L-thiazolidine-4-carboxylic acid as a source of cysteine in parenteral nutrition].
    Infusionstherapie (Basel, Switzerland), 1988, Volume: 15, Issue:2

    Topics: Animals; Cysteine; Cystine; Male; Parenteral Nutrition, Total; Rats; Rats, Inbred Strains; Taurine; Thiazoles; Thiazolidines

1988
Glutathione depletion greatly reduces neocarzinostatin cytotoxicity in Chinese hamster V79 cells.
    The Journal of biological chemistry, 1985, Jul-15, Volume: 260, Issue:14

    Topics: Animals; Antibiotics, Antineoplastic; Cell Line; Cell Survival; Chromatography, High Pressure Liquid; Cricetinae; Cricetulus; Cysteine; Glutathione; Pyrrolidonecarboxylic Acid; Thiazoles; Thiazolidines; Zinostatin

1985
Immunotropic compounds. Structure and biological activity of L-cysteine and 1,3-thiazolidine-4-carboxylic acid derivatives.
    Archivum immunologiae et therapiae experimentalis, 1988, Volume: 36, Issue:3

    Topics: Animals; Cysteine; Immunosuppressive Agents; Molecular Conformation; Rats; Thiazoles; Thiazolidines

1988
Intracellular delivery of cysteine.
    Methods in enzymology, 1987, Volume: 143

    Topics: Animals; Biological Transport; Cysteine; Glutathione; Mice; Pyrrolidonecarboxylic Acid; Radioisotope Dilution Technique; Sulfur Radioisotopes; Thiazoles; Thiazolidines; Tissue Distribution

1987
A decrease in cysteine levels causes the glutathione deficiency of aging in the mosquito.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1988, Volume: 187, Issue:2

    Topics: Aedes; Aging; Animals; Antioxidants; Cysteine; Cystine; Glutathione; Glutathione Disulfide; Thiazoles; Thiazolidines

1988
Effect of dietary protein deficiency and L-2-oxothiazolidine-4-carboxylate on the diurnal rhythm of hepatic glutathione in the rat.
    The Journal of nutrition, 1988, Volume: 118, Issue:8

    Topics: Analysis of Variance; Animals; Body Weight; Circadian Rhythm; Cysteine; Diet; Glutathione; Liver; Male; Protein Deficiency; Pyrrolidonecarboxylic Acid; Rats; Rats, Inbred Strains; Thiazoles; Thiazolidines; Time Factors

1988
Effect of L-2-oxothiazolidine-4-carboxylate administration on glutathione and cysteine concentrations in guinea pig liver and kidney.
    Physiological chemistry and physics and medical NMR, 1987, Volume: 19, Issue:1

    Topics: Animals; Cysteine; Glutathione; Guinea Pigs; Kidney; Kinetics; Liver; Male; Pyrrolidonecarboxylic Acid; Thiazoles; Thiazolidines

1987
Prodrugs of L-cysteine as protective agents against acetaminophen-induced hepatotoxicity. 2-(Polyhydroxyalkyl)- and 2-(polyacetoxyalkyl)thiazolidine-4(R)-carboxylic acids.
    Journal of medicinal chemistry, 1987, Volume: 30, Issue:10

    Topics: Acetaminophen; Animals; Buthionine Sulfoximine; Cysteine; Drug Therapy; Glutathione; Liver; Methionine Sulfoximine; Mice; Prodrugs; Rats; Structure-Activity Relationship; Thiazoles; Thiazolidines

1987
Roles of cysteine as both precursor of thiazolidine 4-carboxylic acids found in human urine and possible inhibitor of endogenous N-nitrosation.
    IARC scientific publications, 1987, Issue:84

    Topics: Cysteine; Fourier Analysis; Humans; In Vitro Techniques; Magnetic Resonance Spectroscopy; Nitroso Compounds; Thiazoles; Thiazolidines

1987
Intracellular cysteine and glutathione delivery systems.
    Journal of the American College of Nutrition, 1986, Volume: 5, Issue:2

    Topics: Acetaminophen; Animals; Biological Transport, Active; Cysteine; Dipeptides; Glutathione; Intracellular Fluid; Kidney; Liver; Mice; Models, Biological; Pyroglutamate Hydrolase; Pyrrolidonecarboxylic Acid; Sulfur; Thiazoles; Thiazolidines

1986
Effects of cysteine pro-drugs on acetaminophen-induced hepatotoxicity.
    The Journal of pharmacology and experimental therapeutics, 1986, Volume: 237, Issue:1

    Topics: Acetaminophen; Acetylcysteine; Animals; Biotransformation; Cysteine; Glucuronates; Glucuronic Acid; Glutathione; Kinetics; Liver; Liver Glycogen; Male; Mice; Phosphoadenosine Phosphosulfate; Protein Binding; Pyrrolidonecarboxylic Acid; Structure-Activity Relationship; Thiazoles; Thiazolidines

1986
Thiazolidine-2-carboxylate derivatives formed from glyoxylate and L-cysteine or L-cysteinylglycine as possible physiological substrates for D-aspartate oxidase.
    Biochemical and biophysical research communications, 1984, Dec-28, Volume: 125, Issue:3

    Topics: Amino Acid Oxidoreductases; Animals; Aspartic Acid; Cattle; Cysteine; D-Aspartate Oxidase; Dipeptides; Glutamates; Glutamic Acid; Glyoxylates; Hydrogen-Ion Concentration; Proline; Substrate Specificity; Thiazolidines

1984
Inhibition of glutathione efflux in the recirculating rat liver perfusion by cysteine but not by oxothiazolidine carboxylate, an intracellular cysteine precursor.
    FEBS letters, 1984, Dec-10, Volume: 178, Issue:2

    Topics: Animals; Cysteine; Glutathione; In Vitro Techniques; Kinetics; Liver; Male; Perfusion; Pyrrolidonecarboxylic Acid; Rats; Rats, Inbred Strains; Thiazoles; Thiazolidines

1984
Formation of 2-methyl-2,4-thiazolidinedicarboxylic acid from L-cysteine in rat tissues.
    Acta biochimica Polonica, 1984, Volume: 31, Issue:3

    Topics: Animals; Biotransformation; Cystathionine gamma-Lyase; Cysteine; Hydrogen-Ion Concentration; In Vitro Techniques; Mitochondria, Liver; Pyruvates; Pyruvic Acid; Rats; Spectrophotometry, Ultraviolet; Thiazoles; Thiazolidines; Time Factors; Tissue Distribution

1984
Presence in human urine of new sulfur-containing N-nitrosamino acids: N-nitrosothiazolidine 4-carboxylic acid and N-nitroso 2-methylthiazolidine 4-carboxylic acid.
    IARC scientific publications, 1984, Issue:57

    Topics: Chemical Phenomena; Chemistry; Cysteine; Humans; Nitroso Compounds; Smoking; Thiazoles; Thiazolidines

1984
Presence in human urine of a new N-nitroso compound, N-nitrosothiazolidine 4-carboxylic acid.
    Cancer letters, 1983, Volume: 20, Issue:2

    Topics: Chromatography, Gas; Chromatography, High Pressure Liquid; Cysteine; Formaldehyde; Gas Chromatography-Mass Spectrometry; Humans; Nitrates; Nitroso Compounds; Thiazoles; Thiazolidines

1983
Urinary excretion products of formaldehyde in the rat.
    Chemico-biological interactions, 1984, Volume: 48, Issue:2

    Topics: Animals; Chromatography, High Pressure Liquid; Chromatography, Ion Exchange; Cysteine; Formaldehyde; Mass Spectrometry; Rats; Rats, Inbred Strains; Thiazoles; Thiazolidines

1984
Intracellular cysteine delivery system that protects against toxicity by promoting glutathione synthesis.
    Proceedings of the National Academy of Sciences of the United States of America, 1982, Volume: 79, Issue:20

    Topics: Acetaminophen; Animals; Cysteine; Glutathione; Glutathione Synthase; Inactivation, Metabolic; Liver; Mice; Pyrrolidonecarboxylic Acid; Thiazoles; Thiazolidines

1982
The metabolism of benzyl isothiocyanate and its cysteine conjugate in guinea-pigs and rabbits.
    Xenobiotica; the fate of foreign compounds in biological systems, 1982, Volume: 12, Issue:9

    Topics: Animals; Chemical Phenomena; Chemistry; Chromatography, Thin Layer; Cysteine; Guinea Pigs; Isothiocyanates; Magnetic Resonance Spectroscopy; Male; Rabbits; Thiazoles; Thiazolidines; Thiocyanates

1982
Metabolism of haloforms to carbon monoxide. IV. studies on the reaction mechanism in vivo.
    Chemico-biological interactions, 1981, Volume: 37, Issue:3

    Topics: Animals; Carbon Monoxide; Carcinogens; Chloroform; Cysteine; Deuterium; Hydrocarbons, Brominated; Male; Maleates; Phenobarbital; Pyrrolidonecarboxylic Acid; Rats; Rats, Inbred Strains; Thiazoles; Thiazolidines; Trihalomethanes

1981
The modulation of IL-2 dependent proliferation of CTLL-2 cells by 2-methyl-thiazolidine-2,4-dicarboxylic acid.
    Immunopharmacology, 1995, Volume: 30, Issue:1

    Topics: Adjuvants, Immunologic; Animals; B-Lymphocytes; Cell Division; Cell Line; Cell Survival; Cysteine; Extracellular Space; Interleukin-2; Intracellular Fluid; Lymphoma, T-Cell; Mice; Sulfhydryl Compounds; T-Lymphocytes, Cytotoxic; Thiazoles; Thiazolidines; Tumor Cells, Cultured

1995
Efficacy of radioprotective agents in preventing small and large bowel radiation injury.
    Diseases of the colon and rectum, 1995, Volume: 38, Issue:7

    Topics: Adenosine Triphosphate; Amifostine; Animals; Cysteine; Drug Therapy, Combination; Glutamine; Intestine, Large; Intestine, Small; Magnesium Chloride; Male; Radiation Dosage; Radiation Injuries, Experimental; Radiation-Protective Agents; Rats; Rats, Sprague-Dawley; Thiazoles; Thiazolidines; Vitamin E

1995
Ethanol-induced changes in the content of thiol compounds and of lipid peroxidation in livers and brains from mice: protection by thiazolidine derivatives.
    Alcohol and alcoholism (Oxford, Oxfordshire), 1994, Volume: 29, Issue:6

    Topics: Alcoholism; Animals; Antioxidants; Brain; Cysteine; Glutathione; Lipid Peroxidation; Liver; Liver Diseases, Alcoholic; Liver Function Tests; Malondialdehyde; Mice; Thiazoles; Thiazolidines

1994
A method for determination of total glutathione and total cysteine as S-carboxymethyl derivatives by using an amino acid analyzer, and its application to samples from rat liver, kidney and blood after intraperitoneal administration of 2-(4-carboxy-D-gluco
    Acta medica Okayama, 1995, Volume: 49, Issue:1

    Topics: Animals; Chromatography, High Pressure Liquid; Cysteine; Glutathione; Injections, Intraperitoneal; Kidney; Liver; Male; Rats; Rats, Wistar; Spectrophotometry; Thiazoles; Thiazolidines

1995
Formation of the L-cysteine-glyoxylate adduct is the mechanism by which L-cysteine decreases oxalate production from glycollate in rat hepatocytes.
    The Biochemical journal, 1994, Sep-15, Volume: 302 ( Pt 3)

    Topics: Animals; Carbon Dioxide; Cysteine; Glycolates; Glyoxylates; Liver; Magnetic Resonance Spectroscopy; Male; Oxalates; Rats; Stereoisomerism; Thiazoles; Thiazolidines

1994
The efficacy of (L)-2-oxothiazolidine-4-carboxylate (OTC) and (L)-cysteine in reducing urinary oxalate excretion.
    The Journal of urology, 1994, Volume: 152, Issue:6 Pt 1

    Topics: Animals; Calcium Oxalate; Cysteine; Male; Metabolism; Pyrrolidonecarboxylic Acid; Rats; Thiazoles; Thiazolidines; Time Factors

1994
Cerulein-induced pancreatic cysteine depletion: prevention does not diminish acute pancreatitis in the mouse.
    Gastroenterology, 1994, Volume: 107, Issue:3

    Topics: Animals; Ceruletide; Cysteine; Dose-Response Relationship, Drug; Female; Glutathione; Mice; Mice, Inbred Strains; Pancreas; Pancreatitis; Pyrrolidonecarboxylic Acid; Thiazoles; Thiazolidines; Time Factors

1994
Thiol metabolism and acute pancreatitis: trying to make the pieces fit.
    Gastroenterology, 1994, Volume: 107, Issue:3

    Topics: Acute Disease; Animals; Ceruletide; Cysteine; Glutathione; Pancreas; Pancreatitis; Pyrrolidonecarboxylic Acid; Sulfhydryl Compounds; Thiazoles; Thiazolidines

1994
Catabolism of cysteine, cystine, cysteinesulfinate, and OTC by isolated perfused rat hindquarter.
    The American journal of physiology, 1993, Volume: 264, Issue:5 Pt 1

    Topics: Adenine Nucleotides; Animals; Cysteine; Cystine; Hindlimb; In Vitro Techniques; Lactates; Male; Muscles; Neurotransmitter Agents; Perfusion; Phosphocreatine; Pyrrolidonecarboxylic Acid; Pyruvates; Radioisotope Dilution Technique; Rats; Rats, Sprague-Dawley; Sulfates; Sulfur Radioisotopes; Taurine; Thiazoles; Thiazolidines

1993
Regulation of hepatocyte glutathione by amino acid precursors and cAMP in protein-energy malnourished rats.
    The Journal of nutrition, 1994, Volume: 124, Issue:3

    Topics: Amino Acids; Animals; Cells, Cultured; Cyclic AMP; Cysteine; Glutathione; Homeostasis; Liver; Male; Methionine; Oxygen; Protein-Energy Malnutrition; Pyrrolidonecarboxylic Acid; Rats; Rats, Wistar; Thiazoles; Thiazolidines

1994
The utilization of N-acetylcysteine and 2-oxothiazolidine-4-carboxylate by rat hepatocytes is limited by their rate of uptake and conversion to cysteine.
    The Journal of nutrition, 1994, Volume: 124, Issue:3

    Topics: Acetylcysteine; Animals; Cells, Cultured; Culture Media; Cysteine; Glutathione; Liver; Male; Pyrrolidonecarboxylic Acid; Rats; Rats, Sprague-Dawley; Selenium Radioisotopes; Thiazoles; Thiazolidines

1994
Mechanism of methylmercury efflux from cultured astrocytes.
    Biochemical pharmacology, 1994, Apr-29, Volume: 47, Issue:9

    Topics: Animals; Astrocytes; Buthionine Sulfoximine; Cells, Cultured; Cysteine; Glutathione; Methionine Sulfoximine; Methylmercury Compounds; Probenecid; Pyrrolidonecarboxylic Acid; Rats; Thiazoles; Thiazolidines

1994
Partial prevention of glutathione depletion in rats following acute intoxication with diethylmaleate.
    Clinical physiology and biochemistry, 1993, Volume: 10, Issue:1

    Topics: Animals; Brain; Cysteine; Glutathione; Heart; Kidney; Liver; Male; Maleates; Myocardium; Pyrrolidonecarboxylic Acid; Rats; Rats, Sprague-Dawley; Thiazoles; Thiazolidines

1993
Protective effect of RibCys following high-dose irradiation of the rectosigmoid.
    Diseases of the colon and rectum, 1993, Volume: 36, Issue:7

    Topics: Anastomosis, Surgical; Animals; Cobalt Radioisotopes; Colon, Sigmoid; Cysteine; Male; Oxygen Consumption; Pressure; Prodrugs; Radiation Dosage; Radiation Injuries, Experimental; Radiation-Protective Agents; Radioisotope Teletherapy; Rectum; Rupture; Swine; Thiazoles; Thiazolidines

1993
Toxicity evaluations of L-cysteine and Procysteine, a cysteine prodrug, given once intravenously to neonatal rats.
    Toxicology letters, 1993, Volume: 69, Issue:1

    Topics: Animals; Animals, Newborn; Body Weight; Cysteine; Injections, Intravenous; Organ Size; Prodrugs; Pyrrolidonecarboxylic Acid; Rats; Rats, Sprague-Dawley; Thiazoles; Thiazolidines

1993
Toxicity and growth-promoting potential of spermine when fed to chicks.
    Journal of animal science, 1995, Volume: 73, Issue:8

    Topics: Adenosylmethionine Decarboxylase; Animal Feed; Animals; Chickens; Cysteine; Diet; Dose-Response Relationship, Drug; Eating; Glutathione; Kidney; Liver; Male; Muscle, Skeletal; Ornithine; Ornithine Decarboxylase; Polyamines; Putrescine; Pyrrolidonecarboxylic Acid; Spermine; Thiazoles; Thiazolidines

1995
Antioxidant survey to assess antagonism to redox stress using a prokaryotic and an eukaryotic system.
    Experientia, 1996, Jun-15, Volume: 52, Issue:6

    Topics: Antioxidants; Buthionine Sulfoximine; Cysteine; Escherichia coli; Eukaryota; Free Radicals; Glutathione; Homocysteine; Methionine Sulfoximine; Oxidative Stress; Pyrrolidonecarboxylic Acid; Thiazoles; Thiazolidines; Vitamin K; Vitamin K 3

1996
Activity and distribution of the cysteine prodrug activating enzyme, 5-oxo-L-prolinase, in human normal and tumor tissues.
    Cancer letters, 1997, Jul-15, Volume: 117, Issue:1

    Topics: Cysteine; Humans; Neoplasms; Prodrugs; Pyroglutamate Hydrolase; Pyrrolidonecarboxylic Acid; Thiazoles; Thiazolidines

1997
Effects on interstitial glutathione, cysteine and 5-S-cysteinyldopa of buthionine sulphoximine in human melanoma transplants.
    Melanoma research, 1997, Volume: 7, Issue:4

    Topics: Acetylcysteine; Animals; Antimetabolites, Antineoplastic; Buthionine Sulfoximine; Cysteine; Cysteinyldopa; Drug Interactions; Enzyme Inhibitors; Glutathione; Humans; Melanoma; Mice; Mice, Inbred BALB C; Mice, Nude; Microdialysis; Neoplasm Transplantation; Pyrrolidonecarboxylic Acid; Thiazoles; Thiazolidines

1997
Thiols and selenium: protective effect on human skin fibroblasts exposed to UVA radiation.
    Journal of photochemistry and photobiology. B, Biology, 1997, Volume: 40, Issue:1

    Topics: Acetylcysteine; Antioxidants; Cell Survival; Cells, Cultured; Cysteine; Dose-Response Relationship, Radiation; Female; Fibroblasts; Glutathione; Humans; Pyrrolidonecarboxylic Acid; Radiation-Protective Agents; Skin; Sodium Selenite; Surgery, Plastic; Thiazoles; Thiazolidines; Thiophenes; Ultraviolet Rays

1997
Utilization of cysteine and cysteine precursors for the synthesis of glutathione in astroglial cultures: preference for cystine.
    Glia, 1998, Volume: 22, Issue:1

    Topics: Animals; Astrocytes; Brain; Brain Chemistry; Cell Survival; Cells, Cultured; Cystathionine; Cysteine; Cystine; gamma-Glutamyltransferase; Glutathione; Methionine; Nerve Tissue Proteins; Pyrrolidonecarboxylic Acid; Rats; Rats, Wistar; Thiazoles; Thiazolidines

1998
Role of glutathione in protection against noise-induced hearing loss.
    Brain research, 1998, Feb-16, Volume: 784, Issue:1-2

    Topics: Animals; Antioxidants; Auditory Threshold; Buthionine Sulfoximine; Chromatography, High Pressure Liquid; Cochlea; Cysteine; Evoked Potentials, Auditory, Brain Stem; Female; Glutathione; Guinea Pigs; Hearing Loss, Noise-Induced; Prodrugs; Pyrrolidonecarboxylic Acid; Thiazoles; Thiazolidines

1998
2-Methyl-thiazolidine-2,4-dicarboxylic acid protects against paracetamol induced toxicity in human liver derived HepG2 cells.
    Acta biochimica Polonica, 1997, Volume: 44, Issue:4

    Topics: Acetaminophen; Antidotes; Benzoquinones; Cell Line; Cysteine; Glutathione; Humans; Imines; Liver; Malondialdehyde; Oxidation-Reduction; Prodrugs; Reactive Oxygen Species; Thiazoles; Thiazolidines

1997
The effect of (L)-cysteine and (L)-2-oxothiazolidine-4-carboxylic acid (OTZ) on urinary oxalate excretion: studies using a hyperoxaluric rat model.
    The Journal of urology, 1998, Volume: 159, Issue:6

    Topics: Animals; Cysteine; Disease Models, Animal; Male; Oxalates; Pyrrolidonecarboxylic Acid; Rats; Rats, Inbred Strains; Thiazoles; Thiazolidines; Urinary Calculi

1998
Pharmacokinetics of 2-oxothiazolidine-4-carboxylate, a cysteine prodrug, and cysteine.
    Journal of clinical pharmacology, 1998, Volume: 38, Issue:10

    Topics: Adult; Cysteine; Glutathione; Humans; Infusions, Intravenous; Male; Prodrugs; Pyrrolidonecarboxylic Acid; Thiazoles; Thiazolidines

1998
3-(5-Dimethylamino-1-naphthalenesulphonyl)-2-(3-pyridyl)thiazolidine (YHI-1) selectively inhibits human immunodeficiency virus type 1.
    Antiviral chemistry & chemotherapy, 1998, Volume: 9, Issue:5

    Topics: Animals; Anti-HIV Agents; Antiviral Agents; Cell Line; Cysteine; Drug Resistance; Fishes; HIV Core Protein p24; HIV Protease; HIV-1; Humans; Molecular Structure; Naphthalenes; Nevirapine; Reverse Transcriptase Inhibitors; Thiazoles; Thiazolidines; Virus Replication

1998
N-acetylcysteine, but not methionine or 2-oxothiazolidine-4-carboxylate, serves as cysteine donor for the synthesis of glutathione in cultured neurons derived from embryonal rat brain.
    Neuroscience letters, 1999, Jan-08, Volume: 259, Issue:2

    Topics: Acetylcysteine; Animals; Brain; Cells, Cultured; Cysteine; Female; Glutathione; Methionine; Neurons; Pregnancy; Pyrrolidonecarboxylic Acid; Rats; Rats, Wistar; Thiazoles; Thiazolidines

1999
L-2-[(13)C]oxothiazolidine-4-carboxylic acid: a probe for precursor mobilization for glutathione synthesis.
    American journal of physiology. Endocrinology and metabolism, 2000, Volume: 278, Issue:1

    Topics: Acetaminophen; Adult; Aged; Breath Tests; Calorimetry, Indirect; Carbon Dioxide; Cysteine; Female; Glutathione; Humans; Kinetics; Male; Middle Aged; Models, Biological; Prodrugs; Pyrrolidonecarboxylic Acid; Thiazoles; Thiazolidines

2000
Comparison of N-acetylcysteine and l-2-oxothiazolidine-4-carboxylate as cysteine deliverers and glutathione precursors in human malignant melanoma transplants in mice.
    Cancer chemotherapy and pharmacology, 2000, Volume: 45, Issue:3

    Topics: Acetylcysteine; Animals; Buthionine Sulfoximine; Cysteine; Cysteinyldopa; Enzyme Inhibitors; Glutathione; Humans; Melanoma; Melanoma, Experimental; Mice; Mice, Nude; Microdialysis; Neoplasm Transplantation; Protein Precursors; Pyrrolidonecarboxylic Acid; Thiazoles; Thiazolidines; Transplantation, Heterologous; Tumor Cells, Cultured

2000
Effects of L-2-oxothiazolidine-4-carboxylate on the cytotoxic activity and toxicity of cyclophosphamide in mice bearing B16F10 melanoma liver metastases.
    Melanoma research, 2000, Volume: 10, Issue:2

    Topics: Acrolein; Alkylation; Animals; Antineoplastic Agents, Alkylating; Biotransformation; Cell Division; Cyclophosphamide; Cysteine; Disease Progression; Drug Interactions; Drug Screening Assays, Antitumor; Female; Glutathione; Leukopenia; Liver Neoplasms; Melanoma, Experimental; Mice; Mice, Inbred C57BL; Oxidation-Reduction; Prodrugs; Pyrrolidonecarboxylic Acid; Thiazoles; Thiazolidines

2000
Enhanced potency of human Sonic hedgehog by hydrophobic modification.
    Biochemistry, 2001, Apr-10, Volume: 40, Issue:14

    Topics: Acyl Coenzyme A; Amides; Amino Acid Substitution; Animals; Cell Line; Circular Dichroism; Cysteine; Ethylmaleimide; Fatty Acids; Formaldehyde; Hedgehog Proteins; Humans; Indicators and Reagents; Intracellular Signaling Peptides and Proteins; Iodoacetamide; Membrane Proteins; Mice; Mice, Inbred C3H; Patched Receptors; Peptide Fragments; Protein Binding; Protein Processing, Post-Translational; Proteins; Receptors, Cell Surface; Signal Transduction; Spectrometry, Mass, Electrospray Ionization; Sulfhydryl Compounds; Thiazoles; Thiazolidines; Trans-Activators; Up-Regulation

2001
Thiazolidine prodrugs as protective agents against gamma-radiation-induced toxicity and mutagenesis in V79 cells.
    Journal of medicinal chemistry, 2001, Aug-02, Volume: 44, Issue:16

    Topics: Animals; Antimutagenic Agents; Cell Death; Cell Line; Cricetinae; Cricetulus; Cysteamine; Cysteine; Gamma Rays; Mercaptoethylamines; Mutagenicity Tests; Prodrugs; Radiation-Protective Agents; Structure-Activity Relationship; Sugar Alcohols; Thiazoles; Thiazolidines

2001
Antidiabetic effect of a prodrug of cysteine, L-2-oxothiazolidine-4-carboxylic acid, through CD38 dimerization and internalization.
    The Journal of biological chemistry, 2002, Feb-15, Volume: 277, Issue:7

    Topics: ADP-ribosyl Cyclase; ADP-ribosyl Cyclase 1; Animals; Antigens, CD; Antigens, Differentiation; Antioxidants; Blood Glucose; Calcium; Cell Line; Cell Separation; Cysteine; Dimerization; Disulfides; DNA, Complementary; Dose-Response Relationship, Drug; Flow Cytometry; Glucose; Green Fluorescent Proteins; HeLa Cells; Humans; Hypoglycemic Agents; Immunohistochemistry; Islets of Langerhans; Luminescent Proteins; Membrane Glycoproteins; Mice; Mice, Inbred BALB C; Microscopy, Confocal; Mutagenesis, Site-Directed; Mutation; NAD+ Nucleosidase; Oligonucleotides, Antisense; Pyrrolidonecarboxylic Acid; Signal Transduction; Thiazoles; Thiazolidines; Time Factors; Transfection

2002
Ascorbate, added after irradiation, reduces the mutant yield and alters the spectrum of CD59- mutations in A(L) cells irradiated with high LET carbon ions.
    Journal of radiation research, 2002, Volume: 43 Suppl

    Topics: Animals; Ascorbic Acid; Carbon; CD59 Antigens; Cricetinae; Cysteine; Free Radical Scavengers; Humans; Hybrid Cells; Ions; Linear Energy Transfer; Mutation; Thiazoles; Thiazolidines

2002
N-formylcysteine synthesis in mitochondria from formaldehyde and L-cysteine via thiazolidinecarboxylic acid.
    The Journal of biological chemistry, 1957, Volume: 227, Issue:1

    Topics: Cysteine; Formaldehyde; Liver; Mitochondria; Thiazoles; Thiazolidines

1957
2-Thiazolidinethione-4-carboxylic acid from the reaction of captan with cysteine.
    Science (New York, N.Y.), 1958, Mar-21, Volume: 127, Issue:3299

    Topics: Antifungal Agents; Captan; Carboxylic Acids; Cysteine; Fungicides, Industrial; Thiazoles; Thiazolidines

1958
[Thiazolidine-carboxylic acid, iminothiazolidine-carboxylic acid and thiazane-carboxylic acid as liver protective substances in comparison with cysteine].
    Klinische Wochenschrift, 1958, Apr-15, Volume: 36, Issue:8

    Topics: Carboxylic Acids; Cysteine; Digestion; Humans; Liver; Thiazoles; Thiazolidines

1958
The replacement by thiazolidinecarboxylic acid of exogenous cystine and cysteine.
    The Journal of nutrition, 1958, Dec-10, Volume: 66, Issue:4

    Topics: Cysteine; Cystine; Humans; Thiazoles; Thiazolidines

1958
[THE EFFECT OF LEYK (CYSTEINE DERIVATIVE) ON THE RADIATION INJURY].
    Nihon Igaku Hoshasen Gakkai zasshi. Nippon acta radiologica, 1963, Volume: 23

    Topics: Anemia; Animals; Blood Cell Count; Cysteine; Neoplasms; Pharmacology; Rabbits; Radiation Injuries; Radiation-Protective Agents; Research; Thiazolidines

1963
[EFFECTS OF LEYK FOR ROENTGEN DAMAGE IN MICE].
    Nihon Igaku Hoshasen Gakkai zasshi. Nippon acta radiologica, 1963, Dec-25, Volume: 23

    Topics: Animals; Body Weight; Cysteine; Leukocyte Count; Mice; Pharmacology; Radiation Injuries; Radiation Injuries, Experimental; Radiation-Protective Agents; Research; Thiazolidines

1963
The "pro-drug" RibCys decreases the mutagenicity of high-LET radiation in cultured mammalian cells.
    Radiation research, 2003, Volume: 160, Issue:5

    Topics: Animals; Carbon Radioisotopes; Cell Count; Cell Survival; CHO Cells; Cricetinae; Cricetulus; Cysteine; Dose-Response Relationship, Drug; Dose-Response Relationship, Radiation; Humans; Hybrid Cells; Iron Radioisotopes; Linear Energy Transfer; Lymphocytes; Mutation; Prodrugs; Radiation Dosage; Radiation Tolerance; Radiation-Protective Agents; Thiazoles; Thiazolidines

2003
Bovine 5-oxo-L-prolinase: simple assay method, purification, cDNA cloning, and detection of mRNA in the coronary artery.
    Biological & pharmaceutical bulletin, 2004, Volume: 27, Issue:3

    Topics: Amidohydrolases; Amino Acid Sequence; Animals; Cattle; Cloning, Molecular; Coronary Vessels; Cysteine; DNA, Complementary; Electrophoresis, Polyacrylamide Gel; Humans; In Vitro Techniques; Molecular Sequence Data; Nitrates; Pyrrolidonecarboxylic Acid; Rats; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sequence Homology, Amino Acid; Species Specificity; Thiazoles; Thiazolidines; Vasodilator Agents

2004
A one-pot total synthesis of crambin.
    Angewandte Chemie (International ed. in English), 2004, May-03, Volume: 43, Issue:19

    Topics: Amino Acid Sequence; Chromatography, High Pressure Liquid; Crystallography, X-Ray; Cysteine; Gas Chromatography-Mass Spectrometry; Models, Molecular; Molecular Sequence Data; Nuclear Magnetic Resonance, Biomolecular; Peptides; Plant Proteins; Protein Conformation; Protein Folding; Thiazoles; Thiazolidines

2004
A role for long-lived radicals (LLR) in radiation-induced mutation and persistent chromosomal instability: counteraction by ascorbate and RibCys but not DMSO.
    Mutation research, 2004, Jul-13, Volume: 551, Issue:1-2

    Topics: Animals; Ascorbic Acid; Carbon; CD59 Antigens; Chromosomal Instability; Cricetinae; Cricetulus; Cysteine; Dimethyl Sulfoxide; Humans; Hybrid Cells; Hypoxanthine Phosphoribosyltransferase; Linear Energy Transfer; Mutation; Radiation-Protective Agents; Thiazoles; Thiazolidines

2004
Effect of ribose cysteine pretreatment on hepatic and renal acetaminophen metabolite formation and glutathione depletion.
    Basic & clinical pharmacology & toxicology, 2005, Volume: 96, Issue:6

    Topics: Acetaminophen; Animals; Blood Urea Nitrogen; Buthionine Sulfoximine; Chemical and Drug Induced Liver Injury; Cysteine; Glutathione; In Vitro Techniques; Kidney; Kidney Diseases; L-Iditol 2-Dehydrogenase; Liver; Liver Diseases; Male; Mice; Mice, Inbred Strains; Microsomes, Liver; Prodrugs; Protective Agents; Thiazoles; Thiazolidines

2005
Comparative efficacies of 2 cysteine prodrugs and a glutathione delivery agent in a colitis model.
    Translational research : the journal of laboratory and clinical medicine, 2007, Volume: 150, Issue:2

    Topics: Animals; Colitis; Colon; Cysteine; Dextran Sulfate; Drug Delivery Systems; Glutathione; Interleukin-12; Interleukin-6; Male; Mice; Mice, Inbred ICR; Sucrose; Thiazoles; Thiazolidines; Up-Regulation

2007
Controlling orientations of immobilized oligopeptides using N-terminal cysteine labels.
    Langmuir : the ACS journal of surfaces and colloids, 2008, May-20, Volume: 24, Issue:10

    Topics: Aldehydes; Biochemistry; Crystallization; Cysteine; Electrochemistry; Lysine; Models, Chemical; Oligopeptides; Peptides; Protein Conformation; Protein Structure, Tertiary; Thiazolidines; Trypsin

2008
A critical cysteine residue in monoacylglycerol lipase is targeted by a new class of isothiazolinone-based enzyme inhibitors.
    British journal of pharmacology, 2009, Volume: 157, Issue:6

    Topics: Amino Acid Sequence; Amino Acid Substitution; Animals; Cysteine; Drug Delivery Systems; Enzyme Inhibitors; Glycine; HeLa Cells; Humans; Molecular Sequence Data; Monoacylglycerol Lipases; Mutagenesis, Site-Directed; Rats; Structure-Activity Relationship; Substrate Specificity; Thiazoles; Thiazolidines

2009
Reversible thiazolidine exchange: a new reaction suitable for dynamic combinatorial chemistry.
    Organic letters, 2009, Aug-06, Volume: 11, Issue:15

    Topics: Aldehydes; Combinatorial Chemistry Techniques; Cysteine; Thiazolidines

2009
Cysteine-reactive covalent capture tags for enrichment of cysteine-containing peptides.
    Rapid communications in mass spectrometry : RCM, 2009, Volume: 23, Issue:21

    Topics: Animals; Cross-Linking Reagents; Cysteine; Horses; Humans; Mass Spectrometry; Myoglobin; Peptide Fragments; Proteins; Serum Albumin; Thiazolidines

2009
The action of formaldehyde on the cystine disulphide linkage of wool; the conversion of subfraction A of the combined cystine into combined lanthionine and djenkolic acid and subfraction B into combined thiazolidine-4-carboxylic acid.
    The Biochemical journal, 1947, Volume: 41, Issue:2

    Topics: Alanine; Animals; Cysteine; Cystine; Formaldehyde; Humans; Sulfides; Thiazolidines; Wool

1947
Potential therapeutic advantage of ribose-cysteine in the inhibition of astrocytoma cell proliferation.
    Amino acids, 2011, Volume: 41, Issue:1

    Topics: Animals; Antineoplastic Agents; Astrocytes; Astrocytoma; Cell Proliferation; Cells, Cultured; Cysteine; Drug Evaluation, Preclinical; Glutathione; Humans; Mice; Prodrugs; Structure-Activity Relationship; Thiazolidines

2011
Protective effect of a cysteine prodrug and antioxidant, L-2-oxothiazolidine-4-carboxylate, against ethanol-induced gastric lesions in rats.
    Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie, 2012, Volume: 64, Issue:3

    Topics: Animals; Anti-Ulcer Agents; Antioxidants; Cysteine; Disease Models, Animal; Ethanol; Female; Gastric Mucosa; Male; Prodrugs; Pyrrolidonecarboxylic Acid; Rats; Rats, Wistar; Stomach Ulcer; Thiazolidines

2012
Crystal structures of (2R,4R)-2-(polyhydroxyalkyl)-1,3-thiazolidine-4-carboxylic acids: condensation products of l-cysteine with d-hexoses.
    Carbohydrate research, 2011, Jan-03, Volume: 346, Issue:1

    Topics: Crystallography, X-Ray; Cysteine; Galactose; Hexoses; Mannose; Thiazolidines

2011
Synthesis of thiazolidine thioester peptides and acceleration of native chemical ligation.
    Organic letters, 2011, Mar-18, Volume: 13, Issue:6

    Topics: 3-Mercaptopropionic Acid; Cysteine; Esters; Glyoxylates; Hydrogen-Ion Concentration; Molecular Structure; Peptides; Thiazolidines; Valine

2011
Effect of radioprotective agents in sporulation medium on Bacillus subtilis spore resistance to hydrogen peroxide, wet heat and germicidal and environmentally relevant UV radiation.
    Journal of applied microbiology, 2011, Volume: 110, Issue:6

    Topics: Bacillus subtilis; Culture Media; Cysteine; Cystine; Hot Temperature; Hydrogen Peroxide; Proline; Radiation-Protective Agents; Spores, Bacterial; Thiazolidines; Ultraviolet Rays

2011
Diverse protective roles of the actin cytoskeleton during oxidative stress.
    Cytoskeleton (Hoboken, N.J.), 2011, Volume: 68, Issue:6

    Topics: Actin Cytoskeleton; Actins; Bridged Bicyclo Compounds, Heterocyclic; Cysteine; Cytoskeleton; Oxidation-Reduction; Oxidative Stress; Reactive Oxygen Species; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Thiazolidines

2011
Chemoselective protein and peptide immobilization on biosensor surfaces.
    Methods in molecular biology (Clifton, N.J.), 2011, Volume: 751

    Topics: 3-Mercaptopropionic Acid; Aldehydes; Amino Acid Sequence; Carboxylic Acids; Cysteine; Immobilized Proteins; Ketones; Mesna; Molecular Sequence Data; Oximes; Peptides; Substrate Specificity; Succinimides; Surface Plasmon Resonance; Surface Properties; Thiazolidines

2011
Simple derivatization of aldehydes with D-cysteine and their determination in beverages by liquid chromatography-tandem mass spectrometry.
    Analytica chimica acta, 2011, Sep-30, Volume: 702, Issue:2

    Topics: Aldehydes; Beverages; Chromatography, Liquid; Cysteine; Humans; Hydrogen-Ion Concentration; Reproducibility of Results; Sensitivity and Specificity; Tandem Mass Spectrometry; Temperature; Thiazolidines

2011
A maxed-out liver: a case of acute-on-chronic liver failure.
    Seminars in liver disease, 2011, Volume: 31, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Cysteine; Diagnosis, Differential; End Stage Liver Disease; Hepacivirus; Hepatitis C, Chronic; Hepatorenal Syndrome; Humans; Liver Cirrhosis; Liver Failure, Acute; Liver Transplantation; Male; Middle Aged; Thiazolidines

2011
Site-specific chemical modification of antibody fragments using traceless cleavable linkers.
    Nature protocols, 2013, Volume: 8, Issue:11

    Topics: Cysteine; Cytotoxins; Drug Delivery Systems; Immunoglobulin Fragments; Immunoproteins; Oligopeptides; Protein Engineering; Thiazolidines

2013
Site-specific protection and dual labeling of human epidermal growth factor (hEGF) for targeting, imaging, and cargo delivery.
    Chemistry (Weinheim an der Bergstrasse, Germany), 2014, May-12, Volume: 20, Issue:20

    Topics: Cysteine; Diagnostic Imaging; Drug Delivery Systems; Epidermal Growth Factor; Humans; Models, Molecular; Molecular Probes; Protein Engineering; Protein Folding; Recombinant Fusion Proteins; Thiazolidines

2014
Differences in heterocycle basicity distinguish homocysteine from cysteine using aldehyde-bearing fluorophores.
    Chemical communications (Cambridge, England), 2014, Aug-04, Volume: 50, Issue:60

    Topics: Aldehydes; Alkalies; Cysteine; Fluorescent Dyes; Homocysteine; Hydrogen-Ion Concentration; Models, Molecular; Molecular Structure; Spectrometry, Fluorescence; Thiazolidines

2014
A fluorescence turn-on probe for cysteine and homocysteine based on thiol-triggered benzothiazolidine ring formation.
    Analytica chimica acta, 2014, Nov-07, Volume: 849

    Topics: Animals; Cell Line; Cysteine; Fluorescent Dyes; Homocysteine; Limit of Detection; Mice; Microscopy, Fluorescence; Optical Imaging; Spectrometry, Fluorescence; Sulfhydryl Compounds; Thiazolidines

2014
A short stereoselective synthesis of prepiscibactin using a SmI2-mediated Reformatsky reaction and Zn2+-induced asymmetric thiazolidine formation.
    Organic letters, 2014, Nov-07, Volume: 16, Issue:21

    Topics: Animals; Cysteine; Fish Diseases; Fishes; Iodides; Molecular Structure; Nitriles; Pasteurella Infections; Pfiesteria piscicida; Photobacterium; Samarium; Stereoisomerism; Thiazoles; Thiazolidines; Zinc

2014
Thiazolidine derivatives from fluorescent dithienyl-BODIPY-carboxaldehydes and cysteine.
    The Journal of organic chemistry, 2014, Dec-05, Volume: 79, Issue:23

    Topics: Boron Compounds; Cysteine; Fluorescent Dyes; Magnetic Resonance Spectroscopy; Molecular Structure; Pyrroles; Spectrometry, Fluorescence; Sulfhydryl Compounds; Thiazolidines

2014
Access to large cyclic peptides by a one-pot two-peptide segment ligation/cyclization process.
    Organic letters, 2015, Jan-02, Volume: 17, Issue:1

    Topics: Cyclization; Cysteine; Ligation; Molecular Structure; Peptides, Cyclic; Thiazolidines

2015
D-ribose-L-cysteine supplementation enhances wound healing in a rodent model.
    American journal of surgery, 2015, Volume: 210, Issue:1

    Topics: Animals; Cysteine; Dietary Supplements; Male; Models, Animal; Rats; Rats, Sprague-Dawley; Thiazolidines; Wound Healing

2015
The cysteine releasing pattern of some antioxidant thiazolidine-4-carboxylic acids.
    European journal of medicinal chemistry, 2016, May-23, Volume: 114

    Topics: Antioxidants; Cysteine; Molecular Structure; Thiazolidines

2016
Palladium Mediated Rapid Deprotection of N-Terminal Cysteine under Native Chemical Ligation Conditions for the Efficient Preparation of Synthetically Challenging Proteins.
    Journal of the American Chemical Society, 2016, Apr-20, Volume: 138, Issue:15

    Topics: Amino Acid Sequence; Cysteine; Molecular Sequence Data; Palladium; Proteins; Thiazolidines

2016
Carbon-sulfur bond-forming reaction catalysed by the radical SAM enzyme HydE.
    Nature chemistry, 2016, Volume: 8, Issue:5

    Topics: Carbon; Catalysis; Catalytic Domain; Clostridium acetobutylicum; Cysteine; Free Radicals; Ligands; Models, Chemical; Oxidoreductases Acting on Sulfur Group Donors; Quantum Theory; S-Adenosylmethionine; Sulfur; Thermotoga maritima; Thiazolidines

2016
Synthesis, Characterization, and Evaluation of Thiazolidine Derivatives of Cysteine for Suppressing Eumelanin Production.
    Chemical & pharmaceutical bulletin, 2016, Volume: 64, Issue:12

    Topics: Crystallography, X-Ray; Cysteine; Melanins; Models, Molecular; Molecular Conformation; Skin Lightening Preparations; Thiazolidines

2016
Thiazolidine reacts with thioreactive biomolecules.
    Free radical biology & medicine, 2017, Volume: 104

    Topics: Acute Pain; Animals; Cysteine; Glutathione; Humans; Inflammation; Mice; Mutagenesis; Nerve Tissue Proteins; Thiazolidines; TRPA1 Cation Channel

2017
Effect of D-ribose-L-cysteine on aluminum induced testicular damage in male Sprague-Dawley rats.
    JBRA assisted reproduction, 2017, 06-01, Volume: 21, Issue:2

    Topics: Aluminum; Animals; Cysteine; Histocytochemistry; Male; Rats; Rats, Sprague-Dawley; Testicular Diseases; Testis; Thiazolidines

2017
Direct synthesis of N-terminal thiazolidine-containing peptide thioesters from peptide hydrazides.
    Chemical communications (Cambridge, England), 2018, Aug-14, Volume: 54, Issue:66

    Topics: Amino Acid Sequence; Cysteine; Esters; Hydrazines; Peptides; Sodium Nitrite; Thiazolidines; Trifluoroacetic Acid

2018
Palladium prompted on-demand cysteine chemistry for the synthesis of challenging and uniquely modified proteins.
    Nature communications, 2018, 08-08, Volume: 9, Issue:1

    Topics: Amino Acid Sequence; Amino Acids; Copper; Cysteine; Deubiquitinating Enzymes; Histones; Nucleosomes; Palladium; Protein Processing, Post-Translational; Proteins; Staining and Labeling; Thiazolidines; Ubiquitinated Proteins

2018
N-acetylcysteine ethyl ester as GSH enhancer in human primary endothelial cells: A comparative study with other drugs.
    Free radical biology & medicine, 2018, Volume: 126

    Topics: Acetylcysteine; Cell Proliferation; Culture Media; Cysteine; Endothelial Cells; Ethyl Ethers; Glutathione; Human Umbilical Vein Endothelial Cells; Humans; Pyrrolidonecarboxylic Acid; Thiazolidines

2018
Identification and Quantitation of Four New 2-Alkylthiazolidine-4-carboxylic Acids Formed in Orange Juice by a Reaction of Saturated Aldehydes with Cysteine.
    Journal of agricultural and food chemistry, 2018, Oct-24, Volume: 66, Issue:42

    Topics: Aldehydes; Citrus sinensis; Cysteine; Food Storage; Fruit and Vegetable Juices; Molecular Structure; Odorants; Temperature; Terpenes; Thiazolidines

2018
Therapeutic Role of a Cysteine Precursor, OTC, in Ischemic Stroke Is Mediated by Improved Proteostasis in Mice.
    Translational stroke research, 2020, Volume: 11, Issue:1

    Topics: Adaptor Proteins, Signal Transducing; Animals; Autophagy-Related Proteins; Brain Ischemia; Cells, Cultured; Cysteine; Ischemic Stroke; Male; Mice, Inbred C57BL; Neurons; Oxidative Stress; Proteostasis; Pyrrolidonecarboxylic Acid; Thiazolidines

2020
Interaction of Added l-Cysteine with 2-Threityl-thiazolidine-4-carboxylic Acid Derived from the Xylose-Cysteine System Affecting Its Maillard Browning.
    Journal of agricultural and food chemistry, 2019, Aug-07, Volume: 67, Issue:31

    Topics: Chromatography, High Pressure Liquid; Cysteine; Glycation End Products, Advanced; Hot Temperature; Maillard Reaction; Thiazolidines; Xylose

2019
D-Ribose-L-cysteine attenuates lipopolysaccharide-induced memory deficits through inhibition of oxidative stress, release of proinflammatory cytokines, and nuclear factor-kappa B expression in mice.
    Naunyn-Schmiedeberg's archives of pharmacology, 2020, Volume: 393, Issue:5

    Topics: Animals; Antioxidants; Behavior, Animal; Brain; Cysteine; Cytokines; Disease Models, Animal; Inflammation Mediators; Lipopolysaccharides; Male; Maze Learning; Memory; Memory Disorders; Mice; NF-kappa B; Oxidative Stress; Recognition, Psychology; Signal Transduction; Social Behavior; Thiazolidines

2020
D-ribose-L-cysteine enhances memory task, attenuates oxidative stress and acetyl-cholinesterase activity in scopolamine amnesic mice.
    Drug development research, 2020, Volume: 81, Issue:5

    Topics: Acetylcholinesterase; Amnesia; Animals; Antioxidants; Brain; Catalase; Cysteine; Glutathione; Male; Malondialdehyde; Memory; Mice; Neuroprotective Agents; Oxidative Stress; Scopolamine; Thiazolidines

2020
Thioproline formation as a driver of formaldehyde toxicity in Escherichia coli.
    The Biochemical journal, 2020, 05-15, Volume: 477, Issue:9

    Topics: Aldehyde Oxidoreductases; Bacterial Proteins; Cysteine; Endopeptidases; Escherichia coli; Formaldehyde; Genes, Bacterial; Genome, Bacterial; Proline; Thiazolidines

2020
Fast and Stable N-Terminal Cysteine Modification through Thiazolidino Boronate Mediated Acyl Transfer.
    Angewandte Chemie (International ed. in English), 2020, 08-17, Volume: 59, Issue:34

    Topics: Acylation; Boronic Acids; Cysteine; Electrophoresis, Polyacrylamide Gel; Hydrolysis; Kinetics; Thiazolidines

2020
2-(3-Hydroxy-5-phosphonooxymethyl-2-methyl-4-pyridyl)-1,3-thiazolidine-4-carboxylic Acid, Novel Metabolite of Pyridoxal 5'-Phosphate and Cysteine Is Present in Human Plasma-Chromatographic Investigations.
    International journal of molecular sciences, 2020, May-18, Volume: 21, Issue:10

    Topics: Cysteine; Gas Chromatography-Mass Spectrometry; Humans; Plasma; Pyridoxal Phosphate; Thiazolidines

2020
LC-MS/MS Coupled with a Stable-Isotope Dilution Method for the Quantitation of Thioproline-Glycine: A Novel Metabolite in Formaldehyde- and Oxidative Stress-Exposed Cells.
    Chemical research in toxicology, 2020, 07-20, Volume: 33, Issue:7

    Topics: Biomarkers; Chromatography, Liquid; Cysteine; Formaldehyde; Glutathione; Glycine; Hep G2 Cells; Humans; Indicator Dilution Techniques; Oxidative Stress; Tandem Mass Spectrometry; Thiazolidines

2020
Transformation between 2-Threityl-thiazolidine-4-carboxylic Acid and Xylose-Cysteine Amadori Rearrangement Product Regulated by pH Adjustment during High-Temperature Instantaneous Dehydration.
    Journal of agricultural and food chemistry, 2020, Sep-30, Volume: 68, Issue:39

    Topics: Cysteine; Glycation End Products, Advanced; Hot Temperature; Hydrogen-Ion Concentration; Maillard Reaction; Thiazolidines; Water; Xylose

2020
D-Ribose-L-cysteine exhibits adaptogenic-like activity through inhibition of oxido-inflammatory responses and increased neuronal caspase-3 activity in mice exposed to unpredictable chronic mild stress.
    Molecular biology reports, 2020, Volume: 47, Issue:10

    Topics: Animals; Apoptosis; Brain; Caspase 3; Chronic Disease; Cysteine; Inflammation; Male; Mice; Neurons; Stress, Psychological; Thiazolidines

2020
On-Demand Detachment of Succinimides on Cysteine to Facilitate (Semi)Synthesis of Challenging Proteins.
    Journal of the American Chemical Society, 2020, 11-18, Volume: 142, Issue:46

    Topics: Catalysis; Coordination Complexes; Cycloaddition Reaction; Cysteine; Disulfides; Globins; Inteins; Maleimides; Palladium; Peptides; Proteins; Solid-Phase Synthesis Techniques; Succinimides; Thiazolidines; Thioredoxins; Ubiquitin; Ubiquitin Thiolesterase

2020
Neurotherapeutic and antioxidant response of D-ribose-L-Cysteine nutritional dietary supplements on Alzheimer-type hippocampal neurodegeneration induced by cuprizone in adult male wistar rat model.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2021, Volume: 147

    Topics: Alzheimer Disease; Animals; Antioxidants; Catalase; Cuprizone; Cysteine; Diet; Dietary Supplements; Food Contamination; Glutathione Synthase; Hippocampus; Male; Malondialdehyde; Nitric Oxide; Oxidative Stress; Rats; Rats, Wistar; Superoxide Dismutase; Thiazolidines

2021
D-ribose-L-cysteine modulates lead acetate-induced hematobiochemical alterations, hormonal imbalance, and ovarian toxicity in adult female Wistar rats.
    Drug and chemical toxicology, 2022, Volume: 45, Issue:4

    Topics: Acetates; Animals; Cysteine; Female; Lead; Ovary; Oxidative Stress; Rats; Rats, Wistar; Thiazolidines

2022
Potential anti-toxic effect of d-ribose-l-cysteine supplement on the reproductive functions of male rats administered cyclophosphamide.
    Journal of basic and clinical physiology and pharmacology, 2021, Feb-09, Volume: 32, Issue:5

    Topics: Animals; Cyclophosphamide; Cysteine; Male; Protective Agents; Rats; Rats, Sprague-Dawley; Testis; Thiazolidines

2021
D-ribose-L-cysteine prevents oxidative stress and cardiometabolic syndrome in high fructose high fat diet fed rats.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2021, Volume: 142

    Topics: Animals; Blood Pressure; Cysteine; Diet, High-Fat; Fructose; Glucose; Heart Rate; Lipid Metabolism; Male; Metabolic Syndrome; Oxidative Stress; Rats; Rats, Wistar; Thiazolidines; Xanthine Oxidase

2021
Degradation of 2-Threityl-Thiazolidine-4-Carboxylic Acid and Corresponding Browning Accelerated by Trapping Reaction between Extra-Added Xylose and Released Cysteine during Maillard Reaction.
    Journal of agricultural and food chemistry, 2021, Sep-15, Volume: 69, Issue:36

    Topics: Cysteine; Maillard Reaction; Thiazolidines; Xylose

2021
D-Ribose-L-Cysteine Improves Glutathione Levels, Neuronal and Mitochondrial Ultrastructural Damage, Caspase-3 and GFAP Expressions Following Manganese-Induced Neurotoxicity.
    Neurotoxicity research, 2021, Volume: 39, Issue:6

    Topics: Animals; Caspase 3; Cysteine; Glial Fibrillary Acidic Protein; Glutathione; Male; Manganese; Microscopy, Electron, Scanning; Mitochondria; Neurotoxicity Syndromes; Rats; Rats, Wistar; Thiazolidines

2021
Kinetics of human pyrroline-5-carboxylate reductase in L-thioproline metabolism.
    Amino acids, 2021, Volume: 53, Issue:12

    Topics: Binding Sites; Cysteine; Humans; Kinetics; Proline; Pyrroles; Pyrroline Carboxylate Reductases; Thiazolidines

2021
Deprotection of S-Acetamidomethyl and 1,3-Thiazolidine-4-Carbonyl Protecting Groups from Cysteine Side Chains in Peptides by
    The Journal of organic chemistry, 2022, 01-21, Volume: 87, Issue:2

    Topics: Cysteine; Disulfides; Kinetics; Peptides; Thiazolidines

2022
d-ribose- l-cysteine abrogates testicular maladaptive responses induced by polychlorinated bisphenol intoxication in rats via activation of the mTOR signaling pathway mediating inhibition of apoptosis, inflammation, and oxidonitrergic flux.
    Journal of biochemical and molecular toxicology, 2022, Volume: 36, Issue:10

    Topics: Animals; Antioxidants; Apoptosis; Autophagy-Related Proteins; Caspase 3; Catalase; Cysteine; Environmental Pollutants; Follicle Stimulating Hormone; Glutathione Peroxidase; Inflammation; Luteinizing Hormone; Male; Malondialdehyde; Mammals; Oxidative Stress; Polychlorinated Biphenyls; Rats; Ribose; Semen; Signal Transduction; Sirolimus; Superoxide Dismutase; Testis; Testosterone; Thiazolidines; TOR Serine-Threonine Kinases; Tumor Necrosis Factor-alpha; Tumor Suppressor Protein p53

2022
Repetitive Thiazolidine Deprotection Using a Thioester-Compatible Aldehyde Scavenger for One-Pot Multiple Peptide Ligation.
    Angewandte Chemie (International ed. in English), 2022, 09-26, Volume: 61, Issue:39

    Topics: Aldehydes; Amino Acids; Cysteine; Formaldehyde; Histones; Peptides; Thiazolidines

2022
Glycine-Xylose Amadori Compound Formation Tracing through Maillard Browning Inhibition by 2-Threityl-thiazolidine-4-carboxylic Acid Formation from Deoxyosone and Exogenous Cysteine.
    Journal of agricultural and food chemistry, 2022, Sep-28, Volume: 70, Issue:38

    Topics: Cysteine; Glycine; Maillard Reaction; Thiazolidines; Xylose

2022
Interactive Bioconjugation at N-Terminal Cysteines by Using O-Salicylaldehyde Esters towards Dual Site-Selective Functionalization.
    Chemistry (Weinheim an der Bergstrasse, Germany), 2022, Dec-01, Volume: 28, Issue:67

    Topics: Aldehydes; Cysteine; Esters; Thiazolidines

2022
Enzyme-independent catabolism of cysteine with pyridoxal-5'-phosphate.
    Scientific reports, 2023, 01-06, Volume: 13, Issue:1

    Topics: Cysteine; Hydrogen Sulfide; Phosphates; Pyridoxal Phosphate; Thiazolidines

2023
Simultaneous determination of 2-(3-hydroxy-5-phosphonooxymethyl-2-methyl-4-pyridyl)-1,3-thiazolidine-4-carboxylic acid and main plasma aminothiols by HPLC-UV based method.
    Scientific reports, 2023, 06-07, Volume: 13, Issue:1

    Topics: Chromatography, High Pressure Liquid; Cysteine; Glutathione; Pyridoxal Phosphate; Reproducibility of Results; Sulfhydryl Compounds; Thiazolidines

2023
A facile bioorthogonal chemistry-based reversible to irreversible strategy to surmount the dilemma between injectability and stability of hyaluronic acid hydrogels.
    Carbohydrate polymers, 2023, Oct-01, Volume: 317

    Topics: Cysteine; Hyaluronic Acid; Hydrogels; Mesenchymal Stem Cells; Sulfhydryl Compounds; Thiazolidines

2023
Three-dimensional quantitative structure-activity relationship analyses of substrates of the human proton-coupled amino acid transporter 1 (hPAT1).
    Bioorganic & medicinal chemistry, 2011, Nov-01, Volume: 19, Issue:21

    Topics: Amino Acid Transport Systems; Caco-2 Cells; Endocytosis; Humans; Kinetics; Models, Chemical; Models, Molecular; Molecular Conformation; Quantitative Structure-Activity Relationship; Substrate Specificity; Symporters

2011