cysteine and thiazoles

cysteine has been researched along with thiazoles in 265 studies

Research

Studies (265)

TimeframeStudies, this research(%)All Research%
pre-199074 (27.92)18.7374
1990's69 (26.04)18.2507
2000's77 (29.06)29.6817
2010's36 (13.58)24.3611
2020's9 (3.40)2.80

Authors

AuthorsStudies
Schonbeck, ND; Shafer, JA; Skalski, M1
Estramareix, B; Gaudry, D; Thérisod, M1
Mitsugi, K; Noda, I; Sano, K; Tamura, F; Yasuda, N; Yokozeki, K1
Krishna, G; Pohl, LR1
Freedland, RA; Simpson, RC1
Ducruix, A; Lunel, J; Pascard, C; Prangé, T1
Ledl, F1
Alexander, CS; Constantino, NV; Goon, DJ; Nagasawa, HT1
McDonald, LJ; Moss, J; Oppenheimer, NJ; Wainschel, LA1
Atzori, L; Cotgreave, I; Grafström, RC; Liu, Y1
DeMaster, EG; Elberling, JA; Nagasawa, HT; Shirota, FN1
Banks, MF; Coloso, RM; Garcia, RA; Stipanuk, MH1
Charyulu, RL; Nagasawa, HT; Roberts, JC; Zera, RT1
Astre, C; Joyeux, H; Possompes, B; Recasens, MA; Saint Aubert, B1
Francetic, DJ; Roberts, JC1
Rommelspacher, H; Schühle, M; Susilo, R1
Leoncini, R; Marinello, E; Pagani, R; Terzuoli, L; Vannoni, D1
Francetic, DJ; Roberts, JC; Zera, RT1
Coloso, RM; Hirschberger, LL; Stipanuk, MH1
Fujimoto, M; Hirata, M; Ohno, K1
Aebi, S; Lauterburg, BH; Porta, P; Summer, K1
Austin, P; Cóllier, PJ; Douglas, KT; Gilbert, P; Ramsey, A; Waigh, RD1
Baker, DH; Chung, TK; Funk, MA1
Ferko, AP1
Akagi, R; Taguchi, T; Ubuka, T1
White, RH1
Anderson, ME; Bridges, RJ; Meister, A; Underwood, M1
Borkowski, L; Iliaszenko, J; Kwapiszewski, W; Sokołowska-Muszyńska, M; Witczak, M1
Anderson, ME; Meister, A2
Böhler, S1
DeGraff, WG; Mitchell, JB; Russo, A1
Włodek, L1
Kwapiszewski, W; Ryzewski, J1
Lang, CA; Richie, JP1
Bauman, PF; Bray, TM; Smith, TK1
Nishina, H; Ohta, J; Ubuka, T1
Fricke, RF; Goon, DJ; Nagasawa, HT; Roberts, JC; Zera, RT1
O'Neill, IK; Ohshima, H1
Anderson, ME; Hwang, O; Meister, A1
Anders, MW; Elfarra, AA; Lash, LH1
Hazelton, GA; Hjelle, JJ; Klaassen, CD1
Katz, N; Pellegrino, J1
Körber, F; Margraf-Modersohn, D; Siegmund, P1
Zsolnai, T2
Ferioli, ME; Gazzola, GC; Guidotti, GG; Loreti, L1
Foote, LJ; Keenan, BS; Kredich, NM1
Schütt, A; Siegers, CP; Strubelt, O1
Lasana, JE; Rauen, HM; Schriewer, H; Tegtbauer, U1
Cooper, AJ; Meister, A1
Gonzales, LJ; Parker, CM; Smith, GG; Sprince, H1
Cobb, WY; Dougherty, RH1
Gochman, N; Schmitz, JM1
Kallen, RG1
Ebata, M; Miyazaki, K; Otsuka, H1
Ando, K; Ikari, N; Nogami, H; Takeuchi, K1
Edwards, K; Jackson, H; Jones, AR2
Hirotsu, Y; Kaneko, T; Shiba, T1
Siegmund, P1
Braven, J; Fenner, ML1
Fuller, NA; Walker, J1
Körber, F; Modersohn, D; Siegmund, P1
Körber, F; Siegmund, P2
Kirsch, JF; Klein, IB1
Angeletti, E; Haertelt, M1
Avchen, B; Overberger, CG; Ringsdorf, H1
Pierpoint, WS1
Barton, MA; Kenner, GW; Sheppard, RC1
Bruggink, JE; Glazenburg, EJ; Mulder, GJ; Wolters-Keulemans, K1
Czubak, J; Włodek, L1
Bartsch, H; Friesen, M; O'Neill, IK; Ohshima, H; Pignatelli, B1
Bartsch, H; Friesen, M; O'Neill, I; Ohshima, H1
Hemminki, K1
Goon, DJ; Muldoon, WP; Nagasawa, HT; Zera, RT1
Fleming, JF; Miquel, J; Weber, HU1
Boettcher, B; Meister, A; Williamson, JM1
Goon, DJ; Nagasawa, HT; Yuzon, DL; Zera, RT1
Anders, MW; Dohn, DR1
Görler, K; Krumbiegel, G; Mennicke, WH; Siehl, HU1
Anders, MW; Stevens, JL1
Grabowska, A; Marcinkiewicz, J; Włodek, L1
Bubrick, MP; Carroll, MP; Feeney, DA; Johnston, GR; Roberts, JC; Schlafmann, SE; West, MA; Zera, RT1
Detrick, SR; Koch, KE; Lubec, G; Roberts, JC; Warters, RL1
Biernat, J; Mandelkow, E; Mandelkow, EM; Schweers, O1
Rommelspacher, H; Wlodek, L1
Chapman, JS; Diehl, MA1
Benet, LZ; Haj-Yehia, AI1
Abe, T; Kinuta, M; Ubuka, T; Yao, WB; Zhao, YQ1
Borum, PR; Chance, M; Emgushov, RT; Jackson, JB; Kalayjian, RC; Mayer, KH; Skowron, G; Spell, SA; Webb, LS; Yen-Lieberman, B1
Bais, R; Baker, PW; Rofe, AM3
Cornelis, S; Devos, R; Foley, LH; Guisez, Y; Plaetinck, G; Scheffler, JE; Tavernier, J; van der Heyden, J1
Bergeron, RJ; Wiegand, J; Wollenweber, M1
Barnidge, M; Janney, CG; Neuschwander-Tetri, BA1
Grendell, JH; Luthen, RE1
Ensunsa, JL; Hirschberger, LL; Stipanuk, MH1
Bray, TM; Goss, PM; Nagy, LE1
Banks, MF; Stipanuk, MH1
Fujiyama, J; Hirayama, K; Yasutake, A1
Höfle, G; Radomski, J; Rommelspacher, H; Susilo, R; Wlodek, L1
Chaudiére, J; Fougeat, S; Gerard-Monnier, D; Gourvest, JF1
Bubrick, MP; Feeney, DA; Fink, AS; Johnston, GR; Madoff, RD; Roberts, JC; Rowe, JK; Young, HL; Zera, RT1
Glosson, JA; Goldberg, DI; Madsen, DC; Rowe, WB; White, RD; Wilson, DM1
Smith, TK; Sousadias, MG1
Baker, ER; Baker, H; DeAngelis, B; Frank, O; Hutner, SH; Khalil, M1
Wróbel, M; Włodek, LB1
Hammerschmidt, R; Zook, M1
Arons, MM; Bernard, GR; Morris, PE; Paz, HL; Russell, JA; Wheeler, AP; Wright, PE1
Ali-Osman, F; Srivenugopal, KS1
Arstrand, K; Dizdar, N; Kågedal, B; Kullman, A1
Beani, JC; Emonet, N; Favier, A; Leccia, MT; Richard, MJ1
Czubak, J; Wróbel, M; Włodek, L1
Dringen, R; Hamprecht, B; Kranich, O; Sandberg, M1
Frei, B; Gokce, N; Holbrook, M; Keaney, JF; Leaf, C; Vita, JA1
Brun, A; Mourier, P1
Harris, C; Miller, JM; Nuttall, AL; Raphael, Y; Yamasoba, T1
Rommelspacher, H; Włodek, L1
Barditch-Crovo, P; Borum, P; Buier, R; Goldberg, D; Kalayjian, RC; Lederman, M; Lietman, P; Noe, D; Rowe, WB; Skowron, G1
Alghamdi, GA; Borum, PR; Jassal, SV; Logan, J; Martis, L; Moberly, JB; Moran, JE; Mupas, L; Oreopoulos, DG; Rodela, H; Story, KO; Webb, LE; Wolfson, M1
Chanal, JL; Delard, R; Dubois, JB; Paul, K; Robbe, Y; Schumacher, C; Sicart, MT; Subra, G1
Chanal, JL; Delard, R; Dubois, JB; Paul, K; Robbe, Y; Schumacher, C; Sicart, MT1
Gehring, AM; Mori, I; Perry, RD; Walsh, CT1
Gwilt, PR; Leaf, CD; Li, XY; Radick, LE; Whalen, JJ1
Arakaki, R; Baba, M; Jinno, S; Nakashima, H; Premanathan, M; Ramanan, S; Yamashita, S1
Dringen, R; Hamprecht, B1
Adams, A; Berger, J; Chen, Y; Elbrecht, A; Griffin, P; Klatt, T; Menke, J; Moller, DE; Smith, RG; Zhang, B; Zhou, G1
Ballaron, SJ; Buko, A; Chen, YW; Chiou, XG; Djurić, SW; Faltynek, CR; Gubbins, EJ; Madar, D; Mollison, KW; Putman, CB; Sheets, MP; Smith, HT; Smith, ML; Tang, QM; Trevillyan, JM; Tu, N; Warrior, UP; Wiedeman, P1
Miller, DA; Suo, Z; Walsh, CT1
Fülöp, F; Lázár, L1
Keating, TA; Patel, HM; Quadri, LE; Walsh, CT1
Ajami, AM; Fukagawa, NK; Hercules, E1
Dizdar, N; Kågedal, B; Kullman, A1
Hammarqvist, F; Wernerman, J1
Ehmann, DE; Keating, TA; Suo, Z; Walsh, CT1
Narla, RK; Perrey, DA; Uckun, FM1
Alonso-Varona, A; Bilbao, P; Calle, Y; Castro, B; del Olmo, M; Palomares, T1
Cho, MK; Kim, SG1
Kelly, JW; Raman, P; Razavi, H1
Suo, Z; Tseng, CC; Walsh, CT1
Chen, TS; Ray, MB; Srinivasan, C; Williams, WM1
Chen, TS; Nagasawa, HT; Srinivasan, C; Williams, WM1
Arduini, RM; Baker, DP; Boriack-Sjodin, A; Carmillo, AN; Day, ES; Galdes, A; Garber, EA; Hronowski, X; Pepinsky, RB; Rayhorn, P; Shapiro, RI; Taylor, FR; Weinreb, PH; Wen, D; Whitty, A; Williams, KP1
Golbik, R; Hübner, G; Jordan, F; Seliger, B; Spinka, M; Tittmann, K; Wang, J1
Hla, T; Inoue , K; Kawahito, Y; Kohno, M; Sano, H; Tsubouchi, Y1
Cassidy, PB; Roberts, JC; Warters, RL; Wilmore, BH1
An, NH; Han, MK; Jang, SI; Kim, HK; Kim, SJ; Kim, UH; Park, HJ; Park, KH; Park, KJ; Park, YR; Shin, YM1
Chavatte, P; Deweer, S; Goossens, JF; Hénichart, JP; Houssin, R; Pommery, J; Salaün, MC1
Assimos, DG; Holmes, RP; Milliner, DS; Wilson, DM1
Goto, Y; Gozu, M; Hasegawa, K; Hong, DP; Naiki, H1
Lapatto, R; Levonen, AL; Nieminen, JM; Otonkoski, T; Rasilainen, S1
Kawai, T; Kohno, S; Miura, M; Nabe, T; Yamashita, K1
Shiba, T; Tadano, M; Takeda, K; Yajima, M1
Asada, Y; Edo, N; Funaki, H; Kawata, M; Mori, K; Narita, M; Nishino, M; Ohmachi, T; Tamura, Y1
Avila-Ríos, S; Gómez-Puyou, A; López-Calahorra, F; Pérez-Montfort, R; Rodríguez-Romero, A; Téllez-Valencia, A; Tuena de Gómez-Puyou, M1
Drozak, J; Winiarska, K1
Audenaert, K; Cornelis, P; Höfte, M; Pattery, T1
Cheng, YQ; Shen, B; Tang, GL1
Becker, D; Brand, P; Knop, J; Valk, E; Zahn, S1
Hashimura, K; Kato, M; Katsube, N; Kohno, H; Maegawa, H; Nakai, K; Ono, S; Seko, T; Takimizu, H; Toda, M1
Fujisawa, M; Ishihara, S; Kanai, M; Koike, H; Mizuno, H; Ohhata, Y; Saito, F; Yorikane, R1
Lenarczyk, M; Ueno, A; Vannais, D; Waldren, CA1
Chen, M; Du, L; Shen, B; Zhang, Y1
Patel, HM; Tao, J; Walsh, CT1
HARRIS, J; MACKENZIE, CG1
CAVALLINI, D; DE MARCO, C; MONDOVI, B1
LUKENS, RJ; SISLER, HD1
EGER, W1
DEBEY, HJ; MACKENZIE, CG; MACKENZIE, JB1
AXELROD, J; HENDERSON, JF; MAZEL, P1
SINGLETON, RJ; SKERMAN, TM1
Santangelo, F1
Hei, TK; Kraemer, S; Kronenberg, A; Lenarczyk, M; Roberts, JC; Tatsumi, K; Ueno, A; Vannais, DB; Waldren, CA1
Iwama, T; Okuda, Y; Yamagata, S; Yasugahira, T1
Farmer, KL; Thomas, MS1
Leonardi, R; Roach, PL1
Abe, K; Iijima, Y; Ishikawa, H; Watanabe, T1
Bai, R; Copeland, TD; Covell, DG; Hamel, E; Kepler, JA; Nguyen, NY; Pettit, GR; Taylor, GF1
Bang, D; Kent, SB1
Ueno, AM; Vannais, DB; Waldren, CA1
Chen, TS; Fu, X; Nagasawa, HT; Ray, MB; Williams, WM1
Barbas, CF; Mase, N; Tanaka, F1
Haas, D; Patel, HM; Reimmann, C; Walsh, CT1
Carnahan, MA; Grinstaff, MW; Jung, PJ; Kim, T; Wathier, M1
Shivaprasad, S; Wetzel, R2
Sebti, SM; Wang, DA1
Chang, SY; Hwang, SL; Kim, CD; Lee, IH; Lee, MH; Park, SJ; Rang, MJ; Rho, SS1
Ishihara, K; Kondo, R; Sakakura, A1
Cohen, SD; Dominick, PK; Roberts, JC; Slitt, AM1
Arana-Ceballos, FA; Brearley, CA; Dörmann, P; Gómez-Merino, FC; Mueller-Roeber, B; Skirycz, A; Trejo-Téllez, LI1
Escobedo, JO; Fakayode, SO; Fletcher, KA; Fronczek, FR; Kim, KK; Lawrence, CM; Lowry, M; Rusin, O; Schowalter, CM; Strongin, RM; Wang, W; Warner, IM; Xu, X1
Szwergold, BS1
Lee, YC; Park, SJ1
Bold, G; Furet, P; Guagnano, V; Meyer, T; Roesel, J1
Bai, G; Jin, Y; Li, Y; Liu, C; Liu, Z; Yang, W; Yu, Y1
Takagi, H; Wada, M1
Kessler, D1
Ami, E; Hamada, Y; Hayashi, Y; Hidaka, K; Kimura, T; Kiso, Y; Nakahara, K; Nakatani, S; Nguyen, JT; Sato, A1
Bartosz, G; Lewinska, A; Slota, E; Wnuk, M1
Amano, W; Azuma, YT; Fujita, A; Fukuhara, A; Hata, F; Inui, T; Nakajima, H; Takeuchi, T1
Chen, TS; Nagasawa, H; Oz, HS1
Ashby, MT; Nagy, P1
Majcherczyk, PA; Mislin, GL; Reimmann, C; Schalk, IJ; Youard, ZA1
Gupta, VB; Rao, KS1
Bai, L; Fen, M; Shi, X; Zhang, X; Zhou, P1
Choi, JW; El-Said, WA; Kim, H; Kim, SU; Lee, B; Min, J; Oh, BK; Yea, CH1
Eisenreich, W; Glawischnig, E; Rauhut, T; Spiteller, M; Spiteller, P1
Aschner, M; Farina, M; Jiang, H; Rocha, JB; Syversen, T; Yin, Z1
Beal, MF; Chen, HL; Gibson, GE; Karuppagounder, SS; Pinto, JT; Xu, H1
Kerk, SY; Lim, TM; Xiong, GG; Zhou, ZD1
Drinkut, A; Falkenburger, BH; Gerhardt, E; Krenz, A; Schulz, JB1
Bednarek, P; Consonni, C; Doubsky, J; Humphry, M; Mansurova, M; Molina, A; Panstruga, R; Pislewska-Bednarek, M; Sanchez-Vallet, A; Schneider, B; Schulze-Lefert, P; Svatos, A1
Carmi, C; Fu, J; King, AR; Lodola, A; Mor, M; Piomelli, D1
Böttcher, C; Glawischnig, E; Prade, E; Scheel, D; Schmotz, C; Westphal, L1
Kelly, JW; Razavi, H; You, SL1
Ang, BU; Kirschner, RE; Nah, HD; Spivak, RM1
Chang, SH; Harocopos, GJ; Huang, AJ; Patel, DA; Thang, DH; Vora, SC1
Chang, JY; Hong, DP; Jiang, C; Xiong, W1
Charman, N; Edmonds, N; Lamy, S; Poon, R; Rigden, M1
Almy, J; de Revel, G; Marchand, S1
Jia, SM; Kong, DM; Li, P; Liu, XF; Shen, HX1
Abeydeera, ND; Bale, S; Begley, TP; Chatterjee, A; Dorrestein, PC; Ealick, SE; Pai, PJ; Russell, DH1
Ludwig, C; Mootz, HD; Schwarzer, D; Thiel, IV1
Bai, F; Bai, G; Du, J; Duan, J; Zhang, Q; Zhao, H1
Deng, B; Hu, J; Hu, Z; Li, W; Liu, Z; Yang, B; Zeng, Y1
Jin, K; Li, X; Yin, Z; Yu, G1
Chen, Y; He, ZH; Li, Q; Liu, XT; Wang, MY; Xu, XJ; Yu, B; Zhang, SQ1
Hyun, JW; Jung, E; Lee, J; Park, D1
Bicker, W; Keller, T; Lamprecht, G; Lindner, W; Reischl, RJ1
Carotti, A; Catto, M; Indiveri, C; Introcaso, A; Koutentis, PA; Koyioni, M; Michaelidou, SS; Nicolotti, O; Oppedisano, F; Pochini, L1
Fan, C; Li, Z; Ye, Q1
Kim, SJ; McAlpine, SR1
Bent, AF; Botting, CH; Fuszard, MA; Houssen, WE; Jaspars, M; Koehnke, J; Morawitz, F; Naismith, JH; Shirran, SL; Smellie, IA; Smith, MC1
Hamada, K; Ishii, K; Iwata, A; Mannen, T; Murayama, S; Saito, Y; Sakurai, Y; Sonoo, M; Sugimoto, I; Tsuji, S1
Chen, Z; Li, L; Tang, B; Tong, LL; Wang, Q1
Boucrot, E; Kirchhausen, T; Santos, AJ; Tacheva-Grigorova, SK1
Johansson, AS; Leinartaitė, L1
Albericio, F; Postma, TM1
Castillo-Villanueva, A; de la Mora-de la Mora, I; Enríquez-Flores, S; Figueroa-Salazar, R; García-Torres, I; Gómez-Manzo, S; Gutiérrez-Castrellón, P; Hernández-Alcántara, G; López-Velázquez, G; Marcial-Quino, J; Méndez, ST; Oria-Hernández, J; Reyes-Vivas, H; Torres-Arroyo, A; Vanoye-Carlo, A; Yépez-Mulia, L1
Jiménez, C; Montaos, MA; Rodríguez, J; Segade, Y1
Dhanalakshmi, B; Gunasekaran, P; Hayakawa, Y; Muthamizhchelvan, C; Navaneethan, M; Nisha, KD; Ponnusamy, S; Saravana Murali, K1
Bent, AF; Botting, C; Houssen, W; Jaspars, M; Koehnke, J; Lebl, T; Ludewig, H; Mann, G; Naismith, JH; Shirran, S1
Liu, T; Lohman, JR; Ma, M; Shen, B1
Berl, V; Debeuckelaere, C; Elbayed, K; Giménez-Arnau, E; Lepoittevin, JP; Moussallieh, FM; Namer, IJ1
Murata, M; Noda, K; Terasawa, N1
Li, H; Li, X; Tang, C; Wang, C; Wang, J; Wei, X; Zhang, C1
Fan, S; Hua, R; Liu, J; Na, R; Tang, J; Wang, Y; Wang, Z; Wu, X; Zhu, M1
Guo, R; Li, B; Li, W; Niu, B; Qiao, M; Wang, H; Xu, H1
Leitsch, D1
Chen, Q; Jiang, Q; Karthik, L; Li, Z; Wang, Y; Zhang, F; Zhao, YL1
Ahmed, F; Anselmi, M; Bassi, M; Carmi, C; Castelli, R; Daglian, J; Dotsey, EY; Ferlenghi, F; Jung, KM; Lodola, A; Mor, M; Møller, IR; Piomelli, D; Rand, KD; Rivara, S; Scalvini, L; Singh, S; Stella, N; Vacondio, F; Vezzosi, S; Wei, D1
Anslyn, EV; Cano, M; Dalby, KN; Ebelt, ND; Edupuganti, R; Ghose, R; Harger, M; Johnson, WH; Kaoud, TS; Park, J; Piserchio, A; Pridgen, JR; Radwan, MF; Ren, P; Sammons, R; Tavares, CDJ; Tsai, KY; Van Ravenstein, SX; Warthaka, M; Zamora-Olivares, D1
Chang, MS; Choi, D; Jang, J; Jung, D; Kang, S; Kim, D; Kim, Y; Lee, Y; Nam, SH; Park, JU; Sim, C1
Borgnia, MJ; He, Q; Hsu, AL; Ji, RR; Lee, SY; Suo, Y; Wang, Z; Zubcevic, L1
Christy, MP; Freiberg, KM; Hamilton, TL; Johnson, T; Lim, B; McNerlin, CD; Nelson, AT; Siegel, D; Woodard, J1
Dong, L; Du, M; Guo, Y; Luo, XL; Ma, YJ; Wang, XY; Xu, XB; Yu, P1
Asaithambi, G; Jebiti, H; Periasamy, V1
Akaji, K1
Kalkreuter, E; Liu, YC; Meng, S; Pan, G; Shen, B; Steele, AD; Xu, Z; Yan, W1
Hayat, K; Ho, CT; Liu, M; Xu, H; Yu, J; Zhang, X; Zhou, T1

Reviews

9 review(s) available for cysteine and thiazoles

ArticleYear
Experimental chemotherapy of Schistosomiasis mansoni.
    Advances in parasitology, 1974, Volume: 12

    Topics: Administration, Oral; Animals; Antimony; Chemosterilants; Child; Cricetinae; Cysteine; Drug Evaluation; Drug Evaluation, Preclinical; Ethylenediamines; Haplorhini; Humans; Injections, Intramuscular; Mice; Nitro Compounds; Nitrofurans; Oxadiazoles; Propylamines; Pyrimidines; Pyrroles; Quinolines; Ribonucleosides; Schistosoma mansoni; Schistosomiasis; Schistosomicides; Thiazoles; Thioxanthenes; Trypsin Inhibitors; Vinyl Compounds

1974
Thiazolidine-4-carboxylic acid, a physiologic sulfhydryl antioxidant with potential value in geriatric medicine.
    Archives of gerontology and geriatrics, 1982, Volume: 1, Issue:4

    Topics: Aged; Animals; Antioxidants; Chemical Phenomena; Chemistry; Cysteine; Dogs; Drug Combinations; Folic Acid; Gastrointestinal Diseases; Humans; Liver Diseases; Longevity; Mice; Rats; Thiazoles; Thiazolidines

1982
Modulation of endogenous glutathione availability.
    Current opinion in clinical nutrition and metabolic care, 1999, Volume: 2, Issue:6

    Topics: Acetylcysteine; Animals; Cysteine; Glutamine; Glutathione; Humans; Protein Precursors; Pyrrolidonecarboxylic Acid; Thiazoles; Thiazolidines

1999
[Glutathione in therapy].
    Postepy higieny i medycyny doswiadczalnej, 2002, Volume: 56, Issue:4

    Topics: Animals; Cysteine; Diabetes Mellitus; Glutathione; Humans; Infections; Neurodegenerative Diseases; Oxidative Stress; Pyrrolidonecarboxylic Acid; Thiazoles; Thiazolidines

2002
Intracellular thiol concentration modulating inflammatory response: influence on the regulation of cell functions through cysteine prodrug approach.
    Current medicinal chemistry, 2003, Volume: 10, Issue:23

    Topics: Acetylcysteine; Acute-Phase Proteins; Animals; Cell Cycle; Cysteine; Cytokines; Glutathione; Humans; Inflammation; Prodrugs; Sulfhydryl Compounds; Thiazoles

2003
Antioxidants as novel agents for asthma.
    Mini reviews in medicinal chemistry, 2006, Volume: 6, Issue:2

    Topics: Acetylcysteine; Anti-Asthmatic Agents; Antioxidants; Asthma; Cysteine; Glutathione; Humans; Oxidative Stress; Pyrrolidonecarboxylic Acid; Reactive Oxygen Species; Thiazoles; Thiazolidines

2006
Metabolic pathways and biotechnological production of L-cysteine.
    Applied microbiology and biotechnology, 2006, Volume: 73, Issue:1

    Topics: Corynebacterium glutamicum; Cysteine; Escherichia coli; Fermentation; Metabolic Networks and Pathways; Thiazoles

2006
Enzymatic activation of sulfur for incorporation into biomolecules in prokaryotes.
    FEMS microbiology reviews, 2006, Volume: 30, Issue:6

    Topics: Bacterial Proteins; Binding Sites; Coenzymes; Cysteine; Enzyme Precursors; Lyases; Models, Molecular; Nitrogen; Nitrogen Fixation; Prokaryotic Cells; Pyridoxal Phosphate; Sulfur; Sulfur Compounds; Thiazoles; Ubiquitin; Vitamins

2006
[Studies on Functional Molecules Based on Peptide Chemistry].
    Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan, 2021, Volume: 141, Issue:2

    Topics: Amino Acids; Amyloid Precursor Protein Secretases; Aspartic Acid Endopeptidases; Biological Products; Chymases; Crystallography, X-Ray; Cysteine; Disulfides; Insulin; Peptides; Protease Inhibitors; Severe acute respiratory syndrome-related coronavirus; Sulfur; Thiazoles

2021

Trials

6 trial(s) available for cysteine and thiazoles

ArticleYear
A phase I/II trial of intravenous L-2-oxothiazolidine-4-carboxylic acid (procysteine) in asymptomatic HIV-infected subjects.
    Journal of acquired immune deficiency syndromes, 1994, Volume: 7, Issue:4

    Topics: Adult; Aged; beta 2-Microglobulin; CD4-Positive T-Lymphocytes; Cysteine; Female; Glutathione; HIV Seropositivity; Humans; Infusions, Intravenous; Leukocyte Count; Male; Middle Aged; Pyrrolidonecarboxylic Acid; Thiazoles; Thiazolidines

1994
A trial of antioxidants N-acetylcysteine and procysteine in ARDS. The Antioxidant in ARDS Study Group.
    Chest, 1997, Volume: 112, Issue:1

    Topics: Acetylcysteine; Adult; Antioxidants; Bilirubin; Bronchoalveolar Lavage Fluid; Cardiac Output; Cysteine; Double-Blind Method; Free Radical Scavengers; Glutathione; Humans; Middle Aged; Prospective Studies; Pyrrolidonecarboxylic Acid; Respiration, Artificial; Respiratory Distress Syndrome; Thiazoles; Thiazolidines; Time Factors

1997
L-2-Oxothiazolidine-4-carboxylic acid reverses endothelial dysfunction in patients with coronary artery disease.
    The Journal of clinical investigation, 1998, Mar-15, Volume: 101, Issue:6

    Topics: Administration, Oral; Aged; Arteriosclerosis; Blood Flow Velocity; Blood Glucose; Blood Pressure; Cholesterol; Coronary Disease; Cysteine; Double-Blind Method; Endothelium, Vascular; Female; Glutathione; Heart Rate; Humans; Hyperemia; Male; Middle Aged; Nitric Oxide; Nitroglycerin; Oxidation-Reduction; Pyrrolidonecarboxylic Acid; Thiazoles; Thiazolidines; Triglycerides; Ultrasonography

1998
A phase I/II evaluation of oral L-2-oxothiazolidine-4-carboxylic acid in asymptomatic patients infected with human immunodeficiency virus.
    Journal of clinical pharmacology, 1998, Volume: 38, Issue:4

    Topics: Adult; Anti-HIV Agents; Cysteine; Dose-Response Relationship, Drug; Double-Blind Method; Glutathione; HIV Infections; Humans; Leukocytes, Mononuclear; Middle Aged; Prodrugs; Pyrrolidonecarboxylic Acid; Thiazoles; Thiazolidines

1998
Elevation of whole-blood glutathione in peritoneal dialysis patients by L-2-oxothiazolidine-4-carboxylate, a cysteine prodrug (Procysteine).
    Journal of the American Society of Nephrology : JASN, 1998, Volume: 9, Issue:6

    Topics: Administration, Oral; Cysteine; Double-Blind Method; Female; Glutathione; Humans; Kidney Failure, Chronic; Male; Middle Aged; Osmolar Concentration; Peritoneal Dialysis, Continuous Ambulatory; Prospective Studies; Pyrrolidonecarboxylic Acid; Thiazoles; Thiazolidines

1998
(L)-2-oxothiazolidine-4-carboxylate in the treatment of primary hyperoxaluria type 1.
    BJU international, 2001, Volume: 88, Issue:9

    Topics: Calcium Oxalate; Calcium, Dietary; Cysteine; Female; Humans; Hyperoxaluria, Primary; Infusions, Intravenous; Male; Middle Aged; Pyrrolidonecarboxylic Acid; Thiazoles; Thiazolidines; Treatment Outcome

2001

Other Studies

250 other study(ies) available for cysteine and thiazoles

ArticleYear
Reactions of pyrzdoxal 5'-phosphate, 6-aminocaproic acid, cysteine, and penicilamine. Models for reactions of Schiff base linkages in pyridoxal 5'-phosphate-requiring enymes.
    The Journal of biological chemistry, 1975, Jul-25, Volume: 250, Issue:14

    Topics: Aminocaproates; Anaerobiosis; Cysteine; Dithionitrobenzoic Acid; Hydrogen-Ion Concentration; Kinetics; Penicillamine; Pyridoxal Phosphate; Schiff Bases; Thiazoles

1975
[Biosynthesis of thiazole from thiamine in Escherichia coli].
    Biochimie, 1977, Volume: 59, Issue:10

    Topics: Cysteine; Escherichia coli; Glutathione; Homocystine; Methionine; Sulfates; Thiamine; Thiazoles

1977
Microbial conversion of DL-2-amino-delta2-thiazoline-4-carboxylic acid to L-cysteine and L-cystine: screening of microorganisms and identification of products.
    Applied and environmental microbiology, 1977, Volume: 34, Issue:6

    Topics: Bacteria; Biological Assay; Carboxylic Acids; Cysteine; Cystine; Optical Rotation; Species Specificity; Stereoisomerism; Thiazoles; X-Ray Diffraction

1977
Deuterium isotope effect in bioactivation and hepatotoxicity of chloroform.
    Life sciences, 1978, Sep-11, Volume: 23, Issue:10

    Topics: Alanine Transaminase; Animals; Chemical and Drug Induced Liver Injury; Chloroform; Cysteine; Cytochrome P-450 Enzyme System; Deuterium; Male; Microsomes, Liver; Phenobarbital; Rats; Thiazoles

1978
The isolation and identification of 2-methyl-2,4-thiazolidine dicarboxylate as a by-product in the conversion of cysteine to glucose in the perfused rat liver.
    Biochimica et biophysica acta, 1977, Jan-24, Volume: 496, Issue:1

    Topics: Animals; Chemical Phenomena; Chemistry; Cysteine; Dicarboxylic Acids; Dietary Proteins; Gluconeogenesis; Kidney; Lactates; Liver; Male; Pyruvates; Rats; Thiazoles; Thiazolidines

1977
Highly modified cysteine-containing antibiotics. Chemical structure and configuration of nosiheptide.
    Journal of the American Chemical Society, 1977, Sep-14, Volume: 99, Issue:19

    Topics: Anti-Bacterial Agents; Chemical Phenomena; Chemistry; Cysteine; Methods; Molecular Conformation; Thiazoles

1977
[Thermal decomposition of cysteine, cystine, N-acetylcysteine, 4-thiazolidinecarboxylic acid and cysteine methyl ester in soy bean oil (authors transl)].
    Zeitschrift fur Lebensmittel-Untersuchung und -Forschung, 1976, Volume: 161, Issue:2

    Topics: Acetylcysteine; Antioxidants; Carboxylic Acids; Cysteine; Cystine; Drug Stability; Esters; Glycine max; Hot Temperature; Oils; Thiazoles

1976
Diversion of ethanol metabolism by sulfhydryl amino acids. D-penicillamine-directed excretion of 2,5,5-trimethyl-D-thiazolidine-4-carboxylic acid in the urine of rats after ethanol administration.
    Life sciences, 1975, Sep-01, Volume: 17, Issue:5

    Topics: Acetaldehyde; Animals; Cysteine; Ethanol; Male; Penicillamine; Rats; Thiazoles

1975
Amino acid-specific ADP-ribosylation: structural characterization and chemical differentiation of ADP-ribose-cysteine adducts formed nonenzymatically and in a pertussis toxin-catalyzed reaction.
    Biochemistry, 1992, Dec-01, Volume: 31, Issue:47

    Topics: Adenosine Diphosphate Ribose; Amino Acids; Animals; Chromatography, High Pressure Liquid; Cysteine; Hydroxylamine; Hydroxylamines; Magnetic Resonance Spectroscopy; Mass Spectrometry; Pertussis Toxin; Rats; Thiazoles; Virulence Factors, Bordetella

1992
The mechanism of Hg2+ toxicity in cultured human oral fibroblasts: the involvement of cellular thiols.
    Chemico-biological interactions, 1992, Nov-30, Volume: 85, Issue:1

    Topics: Buthionine Sulfoximine; Cell Division; Cell Survival; Cells, Cultured; Coloring Agents; Cysteine; Dental Amalgam; Deoxyglucose; Fibroblasts; Glutathione; Humans; Mercury; Methionine Sulfoximine; Mouth; Neutral Red; Sulfhydryl Compounds; Tetrazolium Salts; Thiazoles

1992
Failure of glutathione and cysteine prodrugs to block the chlorpropamide-induced inhibition of aldehyde dehydrogenase in vivo.
    Biochemical pharmacology, 1992, Feb-18, Volume: 43, Issue:4

    Topics: Acetaldehyde; Aldehyde Dehydrogenase; Animals; Chlorpropamide; Cysteine; Ethanol; Glutathione; Male; Prodrugs; Rats; Rats, Inbred Strains; Thiazoles; Thiazolidines

1992
Cysteine concentration regulates cysteine metabolism to glutathione, sulfate and taurine in rat hepatocytes.
    The Journal of nutrition, 1992, Volume: 122, Issue:3

    Topics: Animals; Cells, Cultured; Chelating Agents; Cysteine; Glutathione; Indicators and Reagents; Liver; Male; Methionine; Phenanthrolines; Pyrrolidonecarboxylic Acid; Rats; Rats, Inbred Strains; Sulfates; Taurine; Thiazoles; Thiazolidines

1992
Protection against acetaminophen hepatotoxicity by ribose-cysteine (RibCys).
    Pharmacology & toxicology, 1992, Volume: 70, Issue:4

    Topics: Acetaminophen; Animals; Antidotes; Chemical and Drug Induced Liver Injury; Cysteine; Dose-Response Relationship, Drug; Drug Administration Routes; Drug Administration Schedule; Male; Mice; Prodrugs; Thiazoles; Thiazolidines

1992
Thiazolidine-4-carboxylate and 2-phenylthiazolidine-4-carboxylate are active as cysteine precursors but have no effect on growth of a methionine-dependent tumor in rats.
    The Journal of nutrition, 1992, Volume: 122, Issue:1

    Topics: Amino Acids; Animals; Antineoplastic Agents; Body Weight; Cysteine; Glutathione; Male; Methionine; Rats; Rats, Inbred Strains; Rhabdomyosarcoma; Thiazoles; Thiazolidines

1992
Time course for the elevation of glutathione in numerous organs of L1210-bearing CDF1 mice given the L-cysteine prodrug, RibCys.
    Toxicology letters, 1991, Volume: 59, Issue:1-3

    Topics: Animals; Cysteine; Glutathione; Injections, Intraperitoneal; Leukemia L1210; Liver; Male; Mice; Prodrugs; Thiazoles; Thiazolidines

1991
Detection of a new intermediate product of indolealkylamine metabolism in the brain.
    Advances in experimental medicine and biology, 1991, Volume: 294

    Topics: Animals; Brain Chemistry; Cattle; Cysteine; Indoles; Rats; Swine; Thiazoles; Thiazolidines

1991
High-performance liquid chromatography of thiazolidinic compounds obtained by condensation of pyridoxal 5'-phosphate or pyridoxal with aminothiols (L- or D-cysteine, cysteamine, L-cysteine ethyl ester).
    Journal of chromatography, 1991, Nov-08, Volume: 586, Issue:1

    Topics: Chromatography, High Pressure Liquid; Cysteamine; Cysteine; Liver; Pyridoxal; Pyridoxal Phosphate; Thiazoles; Tissue Extracts

1991
L-cysteine prodrug protects against cyclophosphamide urotoxicity without compromising therapeutic activity.
    Cancer chemotherapy and pharmacology, 1991, Volume: 28, Issue:3

    Topics: Animals; Cyclophosphamide; Cysteine; Dose-Response Relationship, Drug; Drug Interactions; Drug Screening Assays, Antitumor; Glutathione; Leukemia L1210; Male; Mice; Mice, Inbred Strains; Neoplasm Transplantation; Prodrugs; Thiazoles; Thiazolidines; Time Factors; Urinary Bladder

1991
Uptake and metabolism of L-2-oxo-[35S]thiazolidine-4-carboxylate by rat cells is slower than that of L-[35S]cysteine or L-[35S]methionine.
    The Journal of nutrition, 1991, Volume: 121, Issue:9

    Topics: Animals; Biological Transport; Chromatography, High Pressure Liquid; Cysteine; Glutathione; In Vitro Techniques; Intestine, Small; Kidney Tubules; Liver; Male; Methionine; Pyrrolidonecarboxylic Acid; Rats; Rats, Inbred Strains; Sulfur Radioisotopes; Thiazoles; Thiazolidines

1991
Protective effect of prostaglandin A2 against menadione-induced cell injury in cultured porcine aorta endothelial cells.
    Chemico-biological interactions, 1991, Volume: 78, Issue:1

    Topics: Animals; Aorta; Cells, Cultured; Cysteine; Dose-Response Relationship, Drug; Endothelium, Vascular; Glutathione; Methionine; Prostaglandins A; Pyrrolidonecarboxylic Acid; Swine; Thiazoles; Thiazolidines; Time Factors; Vitamin K

1991
L-2-oxothiazolidine-4-carboxylic acid, a cysteine prodrug: pharmacokinetics and effects on thiols in plasma and lymphocytes in human.
    The Journal of pharmacology and experimental therapeutics, 1991, Volume: 257, Issue:1

    Topics: Adult; Cysteine; Glutathione; Humans; Lymphocytes; Male; Middle Aged; Prodrugs; Pyrrolidonecarboxylic Acid; Thiazoles; Thiazolidines

1991
Chemical reactivity of some isothiazolone biocides.
    The Journal of applied bacteriology, 1990, Volume: 69, Issue:4

    Topics: Alcohol Dehydrogenase; Cysteine; Disinfectants; Fungicides, Industrial; Glutathione; Hydrogen-Ion Concentration; Kinetics; Magnetic Resonance Spectroscopy; Oxidation-Reduction; Thiazoles

1990
L-2-oxothiazolidine-4-carboxylate as a cysteine precursor: efficacy for growth and hepatic glutathione synthesis in chicks and rats.
    The Journal of nutrition, 1990, Volume: 120, Issue:2

    Topics: Administration, Oral; Animals; Chickens; Cysteine; Diet; Glutathione; Liver; Male; Pyrrolidonecarboxylic Acid; Random Allocation; Rats; Rats, Inbred Strains; Regression Analysis; Thiazoles; Thiazolidines; Weight Gain

1990
The interaction between ethanol and cysteine on the central depressant effects of ethanol in mice.
    Pharmacology, biochemistry, and behavior, 1990, Volume: 36, Issue:3

    Topics: Animals; Cysteine; Drug Synergism; Ethanol; gamma-Aminobutyric Acid; Injections, Intraventricular; Isethionic Acid; Male; Mice; Posture; Pyrrolidonecarboxylic Acid; Reflex; Thiazoles; Thiazolidines

1990
Tissue contents and urinary excretion of taurine after administration of L-cysteine and L-2-oxothiazolidine-4-carboxylate to rats.
    Acta medica Okayama, 1990, Volume: 44, Issue:3

    Topics: Animals; Caseins; Cysteine; Cysteine Dioxygenase; Cystine; Dietary Proteins; Dioxygenases; Injections, Intraperitoneal; Liver; Male; Oxygenases; Pyrrolidonecarboxylic Acid; Rats; Rats, Inbred Strains; Taurine; Thiazoles; Thiazolidines; Tissue Distribution

1990
Steps in the conversion of alpha-ketosuberate to 7-mercaptoheptanoic acid in methanogenic bacteria.
    Biochemistry, 1989, Nov-28, Volume: 28, Issue:24

    Topics: Cysteine; Dicarboxylic Acids; Euryarchaeota; Heptanoic Acids; Keto Acids; Models, Biological; Phosphothreonine; Sulfhydryl Compounds; Thiazoles; Threonine

1989
Glutathione metabolism at the blood-cerebrospinal fluid barrier.
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 1989, Volume: 3, Issue:13

    Topics: Animals; Antimetabolites; Biological Transport; Blood-Brain Barrier; Buthionine Sulfoximine; Choroid Plexus; Cysteine; Dipeptides; gamma-Glutamyltransferase; Glutathione; Isoxazoles; Male; Methionine Sulfoximine; Pyrrolidonecarboxylic Acid; Rats; Rats, Inbred Strains; Thiazoles; Thiazolidines

1989
Synthesis of L-cysteine derivatives of immunotropic activity.
    Archivum immunologiae et therapiae experimentalis, 1989, Volume: 37, Issue:1-2

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Cysteine; Immunosuppressive Agents; Thiazoles

1989
Marked increase of cysteine levels in many regions of the brain after administration of 2-oxothiazolidine-4-carboxylate.
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 1989, Volume: 3, Issue:5

    Topics: Animals; Brain; Brain Stem; Caudate Nucleus; Cerebellum; Cerebral Cortex; Cysteine; Glutathione; Hypothalamus; Male; Mice; Pons; Pyrrolidonecarboxylic Acid; Rats; Rats, Inbred Strains; Thiazoles; Thiazolidines

1989
[L-thiazolidine-4-carboxylic acid as a source of cysteine in parenteral nutrition].
    Infusionstherapie (Basel, Switzerland), 1988, Volume: 15, Issue:2

    Topics: Animals; Cysteine; Cystine; Male; Parenteral Nutrition, Total; Rats; Rats, Inbred Strains; Taurine; Thiazoles; Thiazolidines

1988
Glutathione depletion greatly reduces neocarzinostatin cytotoxicity in Chinese hamster V79 cells.
    The Journal of biological chemistry, 1985, Jul-15, Volume: 260, Issue:14

    Topics: Animals; Antibiotics, Antineoplastic; Cell Line; Cell Survival; Chromatography, High Pressure Liquid; Cricetinae; Cricetulus; Cysteine; Glutathione; Pyrrolidonecarboxylic Acid; Thiazoles; Thiazolidines; Zinostatin

1985
The reaction of sulfhydryl groups with carbonyl compounds.
    Acta biochimica Polonica, 1988, Volume: 35, Issue:4

    Topics: Chemical Phenomena; Chemistry; Cysteine; Glucose; Glutathione; Ketoglutaric Acids; Kinetics; Malondialdehyde; Pyruvates; Pyruvic Acid; Sulfhydryl Compounds; Thiazoles

1988
Immunotropic compounds. Structure and biological activity of L-cysteine and 1,3-thiazolidine-4-carboxylic acid derivatives.
    Archivum immunologiae et therapiae experimentalis, 1988, Volume: 36, Issue:3

    Topics: Animals; Cysteine; Immunosuppressive Agents; Molecular Conformation; Rats; Thiazoles; Thiazolidines

1988
Intracellular delivery of cysteine.
    Methods in enzymology, 1987, Volume: 143

    Topics: Animals; Biological Transport; Cysteine; Glutathione; Mice; Pyrrolidonecarboxylic Acid; Radioisotope Dilution Technique; Sulfur Radioisotopes; Thiazoles; Thiazolidines; Tissue Distribution

1987
A decrease in cysteine levels causes the glutathione deficiency of aging in the mosquito.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1988, Volume: 187, Issue:2

    Topics: Aedes; Aging; Animals; Antioxidants; Cysteine; Cystine; Glutathione; Glutathione Disulfide; Thiazoles; Thiazolidines

1988
Effect of dietary protein deficiency and L-2-oxothiazolidine-4-carboxylate on the diurnal rhythm of hepatic glutathione in the rat.
    The Journal of nutrition, 1988, Volume: 118, Issue:8

    Topics: Analysis of Variance; Animals; Body Weight; Circadian Rhythm; Cysteine; Diet; Glutathione; Liver; Male; Protein Deficiency; Pyrrolidonecarboxylic Acid; Rats; Rats, Inbred Strains; Thiazoles; Thiazolidines; Time Factors

1988
Effect of L-2-oxothiazolidine-4-carboxylate administration on glutathione and cysteine concentrations in guinea pig liver and kidney.
    Physiological chemistry and physics and medical NMR, 1987, Volume: 19, Issue:1

    Topics: Animals; Cysteine; Glutathione; Guinea Pigs; Kidney; Kinetics; Liver; Male; Pyrrolidonecarboxylic Acid; Thiazoles; Thiazolidines

1987
Prodrugs of L-cysteine as protective agents against acetaminophen-induced hepatotoxicity. 2-(Polyhydroxyalkyl)- and 2-(polyacetoxyalkyl)thiazolidine-4(R)-carboxylic acids.
    Journal of medicinal chemistry, 1987, Volume: 30, Issue:10

    Topics: Acetaminophen; Animals; Buthionine Sulfoximine; Cysteine; Drug Therapy; Glutathione; Liver; Methionine Sulfoximine; Mice; Prodrugs; Rats; Structure-Activity Relationship; Thiazoles; Thiazolidines

1987
Roles of cysteine as both precursor of thiazolidine 4-carboxylic acids found in human urine and possible inhibitor of endogenous N-nitrosation.
    IARC scientific publications, 1987, Issue:84

    Topics: Cysteine; Fourier Analysis; Humans; In Vitro Techniques; Magnetic Resonance Spectroscopy; Nitroso Compounds; Thiazoles; Thiazolidines

1987
Intracellular cysteine and glutathione delivery systems.
    Journal of the American College of Nutrition, 1986, Volume: 5, Issue:2

    Topics: Acetaminophen; Animals; Biological Transport, Active; Cysteine; Dipeptides; Glutathione; Intracellular Fluid; Kidney; Liver; Mice; Models, Biological; Pyroglutamate Hydrolase; Pyrrolidonecarboxylic Acid; Sulfur; Thiazoles; Thiazolidines

1986
Alpha-ketoacids stimulate rat renal cysteine conjugate beta-lyase activity and potentiate the cytotoxicity of S-(1,2-dichlorovinyl)-L-cysteine.
    Molecular pharmacology, 1987, Volume: 31, Issue:2

    Topics: Animals; Benzothiazoles; Cysteine; Drug Synergism; Keto Acids; Kidney; Lyases; Male; Mitochondria; Oxygen Consumption; Rats; Thiazoles; Transaminases

1987
Effects of cysteine pro-drugs on acetaminophen-induced hepatotoxicity.
    The Journal of pharmacology and experimental therapeutics, 1986, Volume: 237, Issue:1

    Topics: Acetaminophen; Acetylcysteine; Animals; Biotransformation; Cysteine; Glucuronates; Glucuronic Acid; Glutathione; Kinetics; Liver; Liver Glycogen; Male; Mice; Phosphoadenosine Phosphosulfate; Protein Binding; Pyrrolidonecarboxylic Acid; Structure-Activity Relationship; Thiazoles; Thiazolidines

1986
[Inhibition of aerobic glycolysis in ascites tumor cells by thiazolidines of L-glyceraldehyde].
    Naunyn-Schmiedebergs Archiv fur Pharmakologie, 1970, Volume: 267, Issue:3

    Topics: Air; Animals; Carcinoma, Ehrlich Tumor; Cysteine; Depression, Chemical; Glyceraldehyde; Glycolysis; Lactates; Mice; Penicillamine; Spectrophotometry; Stereoisomerism; Thiazoles

1970
[Antimicrobial effect of potential isothiocyanate-formers. 5].
    Arzneimittel-Forschung, 1969, Volume: 19, Issue:4

    Topics: Aspergillus; Bacteria; Candida; Cysteine; Entamoeba histolytica; Enterobacter; Epidermophyton; Escherichia coli; Eukaryota; Fungi; Heterocyclic Compounds; Mycobacterium tuberculosis; Penicillium; Peptones; Proteus; Pseudomonas aeruginosa; Saccharomyces; Staphylococcus; Thiazoles; Thiocyanates; Thioglycolates; Trichomonas; Trichophyton

1969
Studies on the anti-tumour activity of aliphatic aldehydes. 3. Formation of thiazoildine-4-carboxylic acid in tissues.
    European journal of cancer, 1971, Volume: 7, Issue:4

    Topics: Aldehydes; Animals; Antineoplastic Agents; Butyrates; Carboxylic Acids; Carcinoma, Hepatocellular; Cysteine; Female; In Vitro Techniques; Liver; Liver Neoplasms; Male; Neoplasms, Experimental; Protein Biosynthesis; Rats; Thiazoles

1971
The stoichiometry and kinetics of the inducible cysteine desulfhydrase from Salmonella typhimurium.
    The Journal of biological chemistry, 1973, Sep-10, Volume: 248, Issue:17

    Topics: Acrylates; Alanine; Amino Acids; Ammonium Sulfate; Bacterial Proteins; Binding, Competitive; Borohydrides; Carboxylic Acids; Cysteine; Enzyme Induction; Hydrogen-Ion Concentration; Kinetics; Lyases; Mathematics; Models, Chemical; Optical Rotatory Dispersion; Pyruvates; Salmonella typhimurium; Streptomycin; Sulfides; Thiazoles

1973
The curative effects of cysteamine, cysteine, and dithiocarb in experimental paracetamol poisoning.
    Archives of toxicology, 1974, Volume: 33, Issue:1

    Topics: Acetaminophen; Alcohols; Animals; Carboxylic Acids; Chemical and Drug Induced Liver Injury; Cysteamine; Cysteine; Dimercaprol; Enzymes; Flavonoids; Glutathione; Lethal Dose 50; Liver; Male; Mice; Penicillamine; Poisoning; Thiazoles; Thiocarbamates; Thioctic Acid

1974
[The effect of aliphatic and heterocyclic mercapto compounds on lipid peroxidation in CCl4-induced liver damage in the rat].
    Arzneimittel-Forschung, 1973, Volume: 23

    Topics: Acrylates; Amides; Animals; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injury; Cyanides; Cysteine; Endoplasmic Reticulum; Homocysteine; Male; Membranes; Microsomes, Liver; Oxidation-Reduction; Peroxides; Phospholipids; Rats; Structure-Activity Relationship; Sulfhydryl Compounds; Thiadiazoles; Thiazoles

1973
Action of liver glutamine transaminase and L-amino acid oxidase on several glutamine analogs. Preparation and properties of the 4-S, O, and NH analogs of alpha-ketoglutaramic acid.
    The Journal of biological chemistry, 1973, Dec-25, Volume: 248, Issue:24

    Topics: Amidohydrolases; Amino Acid Oxidoreductases; Amino Acids, Diamino; Animals; Carbamates; Carboxylic Acids; Chemical Phenomena; Chemistry; Chromatography, Paper; Cysteine; Glutamine; Glyoxylates; Hydrogen Peroxide; Imidazoles; Lactams; Liver; Propionates; Rats; Semicarbazides; Serine; Snakes; Spectrophotometry, Infrared; Spectrophotometry, Ultraviolet; Thiazoles; Transaminases; Urea; Venoms

1973
Protection against acetaldehyde toxicity in the rat by L-cysteine, thiamin and L-2-methylthiazolidine-4-carboxylic acid.
    Agents and actions, 1974, Volume: 4, Issue:2

    Topics: Acetaldehyde; Animals; Carboxylic Acids; Cysteine; Dose-Response Relationship, Drug; Lethal Dose 50; Male; Rats; Rats, Inbred Strains; Thiamine; Thiazoles; Time Factors

1974
Detection of minute thiamine concentrations via thiochrome assay.
    Journal - Association of Official Analytical Chemists, 1971, Volume: 54, Issue:1

    Topics: Amylases; Cysteine; Drug Contamination; Fluorescence; Fluorometry; Papain; Pepsin A; Pyrimidines; Thiamine; Thiazoles

1971
Automated determination of uric acid, with use of a uricase-peroxidase system.
    Clinical chemistry, 1971, Volume: 17, Issue:12

    Topics: Adolescent; Adult; Aniline Compounds; Ascorbic Acid; Autoanalysis; Chemistry, Clinical; Colorimetry; Cysteine; Ergothioneine; Female; Gentisates; Glutathione; Humans; Hydrazones; Hydrogen Peroxide; Male; Methods; Middle Aged; Peroxidases; Spectrophotometry; Thiazoles; Time Factors; Urate Oxidase; Uric Acid

1971
The mechanism of reactions involving Schiff base intermediates. Thiazolidine formation from L-cysteine and formaldehyde.
    Journal of the American Chemical Society, 1971, Volume: 93, Issue:23

    Topics: Amines; Cysteine; Formaldehyde; Kinetics; Schiff Bases; Thiazoles

1971
Studi on siomycin. II. The composition and degradation products of siomycin A.
    The Journal of antibiotics, 1969, Volume: 22, Issue:9

    Topics: Acetaldehyde; Alanine; Amino Acids; Anti-Bacterial Agents; Butyrates; Carbon; Chemical Phenomena; Chemistry; Cysteine; Optical Rotatory Dispersion; Oxidation-Reduction; Propionates; Pyruvates; Quinazolines; Thiazoles; Threonine; Valine

1969
[Thiamine derivatives of disulfide type. X. The exchange reaction between thiazolium disulfide and L-cysteine].
    Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan, 1970, Volume: 90, Issue:4

    Topics: Chemical Phenomena; Chemistry; Chromatography, Thin Layer; Cysteine; Hydrogen-Ion Concentration; Kinetics; Spectrophotometry; Sulfides; Thiamine; Thiazoles

1970
Studies with alkylating esters. II. A chemical interpretation through metabolic studies of the antifertility effects of ethylene dimethanesulphonate and ethylene dibromide.
    Biochemical pharmacology, 1970, Volume: 19, Issue:5

    Topics: Adipose Tissue; Alkylating Agents; Animals; Bile; Bromine; Carbon Isotopes; Chemical Phenomena; Chemistry; Chromatography, Gas; Chromatography, Paper; Cysteine; Esters; Ethanol; Fertility; Hydrocarbons, Halogenated; Intestine, Small; Kidney; Liver; Male; Mice; Ovalbumin; Rats; Spermatozoa; Sulfides; Sulfonic Acids; Sulfoxides; Sulfur Isotopes; Thiazoles

1970
Studies with alkylating esters. 3. The metabolism and fate of methylene dimethanesulphonate.
    Biochemical pharmacology, 1970, Volume: 19, Issue:5

    Topics: Adipose Tissue; Alkylating Agents; Animals; Bone and Bones; Brain; Carbon Isotopes; Chemical Phenomena; Chemistry; Chromatography, Gas; Chromatography, Paper; Cysteine; Epididymis; Esters; Formaldehyde; Formamides; Gastric Mucosa; Hydrolysis; Intestine, Large; Intestine, Small; Kidney; Lung; Male; Methionine; Mice; Muscles; Rats; Skin; Spleen; Sulfonic Acids; Sulfur Isotopes; Testis; Thiazoles

1970
Synthetic studies of bacitracin. V. Synthesis of thiazoline peptides from cysteine peptides by dehydration procedure.
    Bulletin of the Chemical Society of Japan, 1967, Volume: 40, Issue:12

    Topics: Bacitracin; Cysteine; Peptides; Thiazoles

1967
[Alkaline earth chelates of hydrolytically cleavable chelating agents. II. On the synthesis of N-carboxymethylcysteine and its condensation with pyruvic acid].
    Hoppe-Seyler's Zeitschrift fur physiologische Chemie, 1968, Volume: 349, Issue:1

    Topics: Chelating Agents; Cysteine; Hydrogen-Ion Concentration; Pyruvates; Thiazoles

1968
The mechanism of carcinogenesis by tobacco smoke. Further experimental evidence and a prediction from the thiol-defence hypothesis.
    British journal of cancer, 1968, Volume: 22, Issue:3

    Topics: Acetaldehyde; Bronchial Neoplasms; Carbohydrates; Chemical Phenomena; Chemistry; Cysteine; Glucose; Nicotiana; Plants, Toxic; Smoking; Thiazoles

1968
Experiments on the dehydrogenation of some thiazolines derived from cysteine.
    Journal of the Chemical Society. Perkin transactions 1, 1968, Volume: 12

    Topics: Amino Acid Sequence; Chemical Phenomena; Chemistry; Cysteine; Hydrogen; Peptides; Thiazoles

1968
[On photometric titration of thiazolidines with p-mercuribenzoate and its application to the enzymatic-photometric determination of penicillin].
    Zeitschrift fur klinische Chemie und klinische Biochemie, 1968, Volume: 6, Issue:4

    Topics: Benzoates; Cysteine; Glyceraldehyde; Penicillamine; Penicillin G; Penicillinase; Photometry; Sodium Hydroxide; Thiazoles

1968
The fate of calcium, complexed with a metabolizable chelating agent, in the organism.
    Calcified tissue research, 1968

    Topics: Animals; Calcium; Chelating Agents; Chemical Phenomena; Chemistry; Cysteine; Methane; Pyruvates; Rabbits; Rats; Thiazoles

1968
[Alkaline earth chelates of hydrolytically cleavable chelate components. 3. Reaction velocities and equilibrium in aqueous solutions of N-carboxymethylcysteins, pyrivic acid and (2-methyl-2,4-dicarboxy-thiazolidinyl-(3))-acetic acid].
    Hoppe-Seyler's Zeitschrift fur physiologische Chemie, 1968, Volume: 349, Issue:3

    Topics: Acetates; Calcium; Chemical Phenomena; Chemistry; Chloromercuribenzoates; Cysteine; Hydrogen-Ion Concentration; Kinetics; Pyruvates; Solutions; Sulfhydryl Compounds; Thiazoles

1968
The mechanism of the activation of papain.
    Biochemical and biophysical research communications, 1969, Mar-10, Volume: 34, Issue:5

    Topics: Carbon Isotopes; Chemical Phenomena; Chemistry; Chromatography, Gel; Chromatography, Ion Exchange; Chromatography, Paper; Cyanides; Cysteine; Formates; Models, Chemical; Oxidation-Reduction; Papain; Sulfhydryl Compounds; Thiazoles

1969
[Coenzyme activity of 2-(2-methyl-3-hydroxy-4-pyridyl-5-methylphosphoric)-4-thiazolidinecarboxylic acid].
    Bollettino chimico farmaceutico, 1965, Volume: 104, Issue:10

    Topics: Animals; Coenzymes; Cysteine; In Vitro Techniques; Mice; Pyridoxal Phosphate; Thiazoles; Transaminases

1965
Potential antiradiation agents. Preparation and polymerization of monomeric thiazolidines.
    Journal of medicinal chemistry, 1965, Volume: 8, Issue:6

    Topics: Chemical Phenomena; Chemistry; Cysteine; Mercaptoethylamines; Radiation-Protective Agents; Thiazoles

1965
The enzymic oxidation of chlorogenic acid and some reactions of the quinone produced.
    The Biochemical journal, 1966, Volume: 98, Issue:2

    Topics: Ascorbic Acid; Carbamates; Chlorogenic Acid; Chromatography, Paper; Cysteine; Cystine; In Vitro Techniques; Manometry; Nicotiana; Oxidoreductases; Plants, Toxic; Quinones; Sulfinic Acids; Thiazoles; Thioglycolates

1966
Peptides. XXI. Dehydrogenation of some thiazolines derived from cysteine.
    Journal of the Chemical Society. Perkin transactions 1, 1966, Volume: 12

    Topics: Chemical Phenomena; Chemistry; Cysteine; Thiazoles

1966
[The antimicrobial effect of potential isothiocyanate producers].
    Arzneimittel-Forschung, 1966, Volume: 16, Issue:8

    Topics: Animals; Ascaris; Bacteria; Cysteine; Fungi; Glycolates; Halogens; Immune Sera; Nitrogen; Rats; Sulfhydryl Compounds; Thiazoles; Thiocarbamates; Thioglycolates

1966
Inhibition of glutathione efflux in the recirculating rat liver perfusion by cysteine but not by oxothiazolidine carboxylate, an intracellular cysteine precursor.
    FEBS letters, 1984, Dec-10, Volume: 178, Issue:2

    Topics: Animals; Cysteine; Glutathione; In Vitro Techniques; Kinetics; Liver; Male; Perfusion; Pyrrolidonecarboxylic Acid; Rats; Rats, Inbred Strains; Thiazoles; Thiazolidines

1984
Formation of 2-methyl-2,4-thiazolidinedicarboxylic acid from L-cysteine in rat tissues.
    Acta biochimica Polonica, 1984, Volume: 31, Issue:3

    Topics: Animals; Biotransformation; Cystathionine gamma-Lyase; Cysteine; Hydrogen-Ion Concentration; In Vitro Techniques; Mitochondria, Liver; Pyruvates; Pyruvic Acid; Rats; Spectrophotometry, Ultraviolet; Thiazoles; Thiazolidines; Time Factors; Tissue Distribution

1984
Presence in human urine of new sulfur-containing N-nitrosamino acids: N-nitrosothiazolidine 4-carboxylic acid and N-nitroso 2-methylthiazolidine 4-carboxylic acid.
    IARC scientific publications, 1984, Issue:57

    Topics: Chemical Phenomena; Chemistry; Cysteine; Humans; Nitroso Compounds; Smoking; Thiazoles; Thiazolidines

1984
Presence in human urine of a new N-nitroso compound, N-nitrosothiazolidine 4-carboxylic acid.
    Cancer letters, 1983, Volume: 20, Issue:2

    Topics: Chromatography, Gas; Chromatography, High Pressure Liquid; Cysteine; Formaldehyde; Gas Chromatography-Mass Spectrometry; Humans; Nitrates; Nitroso Compounds; Thiazoles; Thiazolidines

1983
Urinary excretion products of formaldehyde in the rat.
    Chemico-biological interactions, 1984, Volume: 48, Issue:2

    Topics: Animals; Chromatography, High Pressure Liquid; Chromatography, Ion Exchange; Cysteine; Formaldehyde; Mass Spectrometry; Rats; Rats, Inbred Strains; Thiazoles; Thiazolidines

1984
2-Substituted thiazolidine-4(R)-carboxylic acids as prodrugs of L-cysteine. Protection of mice against acetaminophen hepatotoxicity.
    Journal of medicinal chemistry, 1984, Volume: 27, Issue:5

    Topics: Acetaminophen; Animals; Carbon Radioisotopes; Cysteine; Indicators and Reagents; Kinetics; Liver; Male; Mice; Mitochondria, Liver; Proline Oxidase; Rats; Rats, Inbred Strains; Structure-Activity Relationship; Thiazoles

1984
Intracellular cysteine delivery system that protects against toxicity by promoting glutathione synthesis.
    Proceedings of the National Academy of Sciences of the United States of America, 1982, Volume: 79, Issue:20

    Topics: Acetaminophen; Animals; Cysteine; Glutathione; Glutathione Synthase; Inactivation, Metabolic; Liver; Mice; Pyrrolidonecarboxylic Acid; Thiazoles; Thiazolidines

1982
Prodrugs of L-cysteine as liver-protective agents. 2(RS)-Methylthiazolidine-4(R)-carboxylic acid, a latent cysteine.
    Journal of medicinal chemistry, 1982, Volume: 25, Issue:5

    Topics: Acetaminophen; Animals; Chemical and Drug Induced Liver Injury; Chemical Phenomena; Chemistry; Cysteine; Magnetic Resonance Spectroscopy; Mice; Thiazoles

1982
Assay of cysteine conjugate beta-lyase activity with S-(2-benzothiazolyl)cysteine as the substrate.
    Analytical biochemistry, 1982, Mar-01, Volume: 120, Issue:2

    Topics: Animals; Benzothiazoles; Carbon-Sulfur Lyases; Cysteine; Liver; Lyases; Male; Mass Spectrometry; Rats; Rats, Inbred Strains; Thiazoles

1982
The metabolism of benzyl isothiocyanate and its cysteine conjugate in guinea-pigs and rabbits.
    Xenobiotica; the fate of foreign compounds in biological systems, 1982, Volume: 12, Issue:9

    Topics: Animals; Chemical Phenomena; Chemistry; Chromatography, Thin Layer; Cysteine; Guinea Pigs; Isothiocyanates; Magnetic Resonance Spectroscopy; Male; Rabbits; Thiazoles; Thiazolidines; Thiocyanates

1982
Metabolism of haloforms to carbon monoxide. IV. studies on the reaction mechanism in vivo.
    Chemico-biological interactions, 1981, Volume: 37, Issue:3

    Topics: Animals; Carbon Monoxide; Carcinogens; Chloroform; Cysteine; Deuterium; Hydrocarbons, Brominated; Male; Maleates; Phenobarbital; Pyrrolidonecarboxylic Acid; Rats; Rats, Inbred Strains; Thiazoles; Thiazolidines; Trihalomethanes

1981
The modulation of IL-2 dependent proliferation of CTLL-2 cells by 2-methyl-thiazolidine-2,4-dicarboxylic acid.
    Immunopharmacology, 1995, Volume: 30, Issue:1

    Topics: Adjuvants, Immunologic; Animals; B-Lymphocytes; Cell Division; Cell Line; Cell Survival; Cysteine; Extracellular Space; Interleukin-2; Intracellular Fluid; Lymphoma, T-Cell; Mice; Sulfhydryl Compounds; T-Lymphocytes, Cytotoxic; Thiazoles; Thiazolidines; Tumor Cells, Cultured

1995
Efficacy of radioprotective agents in preventing small and large bowel radiation injury.
    Diseases of the colon and rectum, 1995, Volume: 38, Issue:7

    Topics: Adenosine Triphosphate; Amifostine; Animals; Cysteine; Drug Therapy, Combination; Glutamine; Intestine, Large; Intestine, Small; Magnesium Chloride; Male; Radiation Dosage; Radiation Injuries, Experimental; Radiation-Protective Agents; Rats; Rats, Sprague-Dawley; Thiazoles; Thiazolidines; Vitamin E

1995
Thiazolidine prodrugs of cysteamine and cysteine as radioprotective agents.
    Radiation research, 1995, Volume: 143, Issue:2

    Topics: Animals; Cell Line; Cricetinae; Cricetulus; Cysteamine; Cysteine; DNA, Single-Stranded; Dose-Response Relationship, Drug; Prodrugs; Radiation-Protective Agents; Thiazoles

1995
Oxidation of cysteine-322 in the repeat domain of microtubule-associated protein tau controls the in vitro assembly of paired helical filaments.
    Proceedings of the National Academy of Sciences of the United States of America, 1995, Aug-29, Volume: 92, Issue:18

    Topics: Alzheimer Disease; Benzothiazoles; Brain; Cysteine; Fluorescent Dyes; Humans; Neurofibrillary Tangles; Oxidation-Reduction; Phosphorylation; Protein Conformation; Sulfhydryl Reagents; tau Proteins; Thiazoles

1995
Ethanol-induced changes in the content of thiol compounds and of lipid peroxidation in livers and brains from mice: protection by thiazolidine derivatives.
    Alcohol and alcoholism (Oxford, Oxfordshire), 1994, Volume: 29, Issue:6

    Topics: Alcoholism; Animals; Antioxidants; Brain; Cysteine; Glutathione; Lipid Peroxidation; Liver; Liver Diseases, Alcoholic; Liver Function Tests; Malondialdehyde; Mice; Thiazoles; Thiazolidines

1994
Methylchloroisothiazolone-induced growth inhibition and lethality in Escherichia coli.
    The Journal of applied bacteriology, 1995, Volume: 78, Issue:2

    Topics: Adenosine Triphosphate; Anti-Bacterial Agents; Bacterial Proteins; Cysteine; DNA-Binding Proteins; Dose-Response Relationship, Drug; Drug Interactions; Escherichia coli; Escherichia coli Proteins; Glucose; Hydroquinones; Oxygen Consumption; Repressor Proteins; Sulfhydryl Compounds; Thiazoles; Transcription Factors

1995
Determination of aliphatic thiols by fluorometric high-performance liquid chromatography after precolumn derivatization with 2-(4-N-maleimidophenyl)-6-methylbenzothiazole.
    Pharmaceutical research, 1995, Volume: 12, Issue:1

    Topics: Animals; Chromatography, High Pressure Liquid; Cysteine; Fluorometry; Glutathione; Indicators and Reagents; Male; Maleimides; Rats; Rats, Sprague-Dawley; Sensitivity and Specificity; Sulfhydryl Compounds; Thiazoles; Tissue Distribution

1995
A method for determination of total glutathione and total cysteine as S-carboxymethyl derivatives by using an amino acid analyzer, and its application to samples from rat liver, kidney and blood after intraperitoneal administration of 2-(4-carboxy-D-gluco
    Acta medica Okayama, 1995, Volume: 49, Issue:1

    Topics: Animals; Chromatography, High Pressure Liquid; Cysteine; Glutathione; Injections, Intraperitoneal; Kidney; Liver; Male; Rats; Rats, Wistar; Spectrophotometry; Thiazoles; Thiazolidines

1995
Formation of the L-cysteine-glyoxylate adduct is the mechanism by which L-cysteine decreases oxalate production from glycollate in rat hepatocytes.
    The Biochemical journal, 1994, Sep-15, Volume: 302 ( Pt 3)

    Topics: Animals; Carbon Dioxide; Cysteine; Glycolates; Glyoxylates; Liver; Magnetic Resonance Spectroscopy; Male; Oxalates; Rats; Stereoisomerism; Thiazoles; Thiazolidines

1994
Covalent modification of the interleukin-5 receptor by isothiazolones leads to inhibition of the binding of interleukin-5.
    European journal of biochemistry, 1994, Oct-15, Volume: 225, Issue:2

    Topics: Amino Acid Sequence; Animals; Binding Sites; Cell Line; Cysteine; Dithiothreitol; Granulocyte-Macrophage Colony-Stimulating Factor; Interleukin-5; Kidney; Macaca; Molecular Sequence Data; Mutagenesis, Site-Directed; Receptors, Interleukin; Receptors, Interleukin-5; Recombinant Proteins; Sulfhydryl Compounds; Thiazoles

1994
The efficacy of (L)-2-oxothiazolidine-4-carboxylate (OTC) and (L)-cysteine in reducing urinary oxalate excretion.
    The Journal of urology, 1994, Volume: 152, Issue:6 Pt 1

    Topics: Animals; Calcium Oxalate; Cysteine; Male; Metabolism; Pyrrolidonecarboxylic Acid; Rats; Thiazoles; Thiazolidines; Time Factors

1994
An investigation of desferrithiocin metabolism.
    Journal of medicinal chemistry, 1994, Sep-02, Volume: 37, Issue:18

    Topics: Animals; Chromatography, High Pressure Liquid; Cysteine; Dihydropyridines; Female; Hydrolysis; Iron; Kinetics; Male; Mice; Rats; Rats, Sprague-Dawley; Siderophores; Thiazoles

1994
Cerulein-induced pancreatic cysteine depletion: prevention does not diminish acute pancreatitis in the mouse.
    Gastroenterology, 1994, Volume: 107, Issue:3

    Topics: Animals; Ceruletide; Cysteine; Dose-Response Relationship, Drug; Female; Glutathione; Mice; Mice, Inbred Strains; Pancreas; Pancreatitis; Pyrrolidonecarboxylic Acid; Thiazoles; Thiazolidines; Time Factors

1994
Thiol metabolism and acute pancreatitis: trying to make the pieces fit.
    Gastroenterology, 1994, Volume: 107, Issue:3

    Topics: Acute Disease; Animals; Ceruletide; Cysteine; Glutathione; Pancreas; Pancreatitis; Pyrrolidonecarboxylic Acid; Sulfhydryl Compounds; Thiazoles; Thiazolidines

1994
Catabolism of cysteine, cystine, cysteinesulfinate, and OTC by isolated perfused rat hindquarter.
    The American journal of physiology, 1993, Volume: 264, Issue:5 Pt 1

    Topics: Adenine Nucleotides; Animals; Cysteine; Cystine; Hindlimb; In Vitro Techniques; Lactates; Male; Muscles; Neurotransmitter Agents; Perfusion; Phosphocreatine; Pyrrolidonecarboxylic Acid; Pyruvates; Radioisotope Dilution Technique; Rats; Rats, Sprague-Dawley; Sulfates; Sulfur Radioisotopes; Taurine; Thiazoles; Thiazolidines

1993
Regulation of hepatocyte glutathione by amino acid precursors and cAMP in protein-energy malnourished rats.
    The Journal of nutrition, 1994, Volume: 124, Issue:3

    Topics: Amino Acids; Animals; Cells, Cultured; Cyclic AMP; Cysteine; Glutathione; Homeostasis; Liver; Male; Methionine; Oxygen; Protein-Energy Malnutrition; Pyrrolidonecarboxylic Acid; Rats; Rats, Wistar; Thiazoles; Thiazolidines

1994
The utilization of N-acetylcysteine and 2-oxothiazolidine-4-carboxylate by rat hepatocytes is limited by their rate of uptake and conversion to cysteine.
    The Journal of nutrition, 1994, Volume: 124, Issue:3

    Topics: Acetylcysteine; Animals; Cells, Cultured; Culture Media; Cysteine; Glutathione; Liver; Male; Pyrrolidonecarboxylic Acid; Rats; Rats, Sprague-Dawley; Selenium Radioisotopes; Thiazoles; Thiazolidines

1994
Mechanism of methylmercury efflux from cultured astrocytes.
    Biochemical pharmacology, 1994, Apr-29, Volume: 47, Issue:9

    Topics: Animals; Astrocytes; Buthionine Sulfoximine; Cells, Cultured; Cysteine; Glutathione; Methionine Sulfoximine; Methylmercury Compounds; Probenecid; Pyrrolidonecarboxylic Acid; Rats; Thiazoles; Thiazolidines

1994
Thiazolidine derivatives as source of free L-cysteine in rat tissue.
    Biochemical pharmacology, 1993, Dec-03, Volume: 46, Issue:11

    Topics: Animals; Cysteine; Cytosol; Dinitrofluorobenzene; Female; Mitochondria, Liver; Oxidation-Reduction; Rats; Rats, Wistar; Thiazoles

1993
Partial prevention of glutathione depletion in rats following acute intoxication with diethylmaleate.
    Clinical physiology and biochemistry, 1993, Volume: 10, Issue:1

    Topics: Animals; Brain; Cysteine; Glutathione; Heart; Kidney; Liver; Male; Maleates; Myocardium; Pyrrolidonecarboxylic Acid; Rats; Rats, Sprague-Dawley; Thiazoles; Thiazolidines

1993
Protective effect of RibCys following high-dose irradiation of the rectosigmoid.
    Diseases of the colon and rectum, 1993, Volume: 36, Issue:7

    Topics: Anastomosis, Surgical; Animals; Cobalt Radioisotopes; Colon, Sigmoid; Cysteine; Male; Oxygen Consumption; Pressure; Prodrugs; Radiation Dosage; Radiation Injuries, Experimental; Radiation-Protective Agents; Radioisotope Teletherapy; Rectum; Rupture; Swine; Thiazoles; Thiazolidines

1993
Toxicity evaluations of L-cysteine and Procysteine, a cysteine prodrug, given once intravenously to neonatal rats.
    Toxicology letters, 1993, Volume: 69, Issue:1

    Topics: Animals; Animals, Newborn; Body Weight; Cysteine; Injections, Intravenous; Organ Size; Prodrugs; Pyrrolidonecarboxylic Acid; Rats; Rats, Sprague-Dawley; Thiazoles; Thiazolidines

1993
Toxicity and growth-promoting potential of spermine when fed to chicks.
    Journal of animal science, 1995, Volume: 73, Issue:8

    Topics: Adenosylmethionine Decarboxylase; Animal Feed; Animals; Chickens; Cysteine; Diet; Dose-Response Relationship, Drug; Eating; Glutathione; Kidney; Liver; Male; Muscle, Skeletal; Ornithine; Ornithine Decarboxylase; Polyamines; Putrescine; Pyrrolidonecarboxylic Acid; Spermine; Thiazoles; Thiazolidines

1995
Antioxidant survey to assess antagonism to redox stress using a prokaryotic and an eukaryotic system.
    Experientia, 1996, Jun-15, Volume: 52, Issue:6

    Topics: Antioxidants; Buthionine Sulfoximine; Cysteine; Escherichia coli; Eukaryota; Free Radicals; Glutathione; Homocysteine; Methionine Sulfoximine; Oxidative Stress; Pyrrolidonecarboxylic Acid; Thiazoles; Thiazolidines; Vitamin K; Vitamin K 3

1996
Selective modulation of non-protein sulfhydryl levels in Ehrlich ascites tumor bearing mice.
    Neoplasma, 1996, Volume: 43, Issue:4

    Topics: Amino Acids; Animals; Carcinoma, Ehrlich Tumor; Cysteine; Female; Glutathione; Liver; Methionine; Mice; Neoplasm Transplantation; Prodrugs; Thiazoles; Thiosulfates

1996
Origin of the thiazole ring of camalexin, a phytoalexin from Arabidopsis thaliana.
    Plant physiology, 1997, Volume: 113, Issue:2

    Topics: Anti-Bacterial Agents; Anti-Infective Agents; Arabidopsis; Chromatography, High Pressure Liquid; Cysteine; Indoles; Mass Spectrometry; ortho-Aminobenzoates; Plant Diseases; Thiazoles

1997
Activity and distribution of the cysteine prodrug activating enzyme, 5-oxo-L-prolinase, in human normal and tumor tissues.
    Cancer letters, 1997, Jul-15, Volume: 117, Issue:1

    Topics: Cysteine; Humans; Neoplasms; Prodrugs; Pyroglutamate Hydrolase; Pyrrolidonecarboxylic Acid; Thiazoles; Thiazolidines

1997
Effects on interstitial glutathione, cysteine and 5-S-cysteinyldopa of buthionine sulphoximine in human melanoma transplants.
    Melanoma research, 1997, Volume: 7, Issue:4

    Topics: Acetylcysteine; Animals; Antimetabolites, Antineoplastic; Buthionine Sulfoximine; Cysteine; Cysteinyldopa; Drug Interactions; Enzyme Inhibitors; Glutathione; Humans; Melanoma; Mice; Mice, Inbred BALB C; Mice, Nude; Microdialysis; Neoplasm Transplantation; Pyrrolidonecarboxylic Acid; Thiazoles; Thiazolidines

1997
Thiols and selenium: protective effect on human skin fibroblasts exposed to UVA radiation.
    Journal of photochemistry and photobiology. B, Biology, 1997, Volume: 40, Issue:1

    Topics: Acetylcysteine; Antioxidants; Cell Survival; Cells, Cultured; Cysteine; Dose-Response Relationship, Radiation; Female; Fibroblasts; Glutathione; Humans; Pyrrolidonecarboxylic Acid; Radiation-Protective Agents; Skin; Sodium Selenite; Surgery, Plastic; Thiazoles; Thiazolidines; Thiophenes; Ultraviolet Rays

1997
Selective effect of 2-(polyhydroxyalkyl)-thiazolidine-4-carboxylic acids on nonprotein sulfhydryl groups in tumor bearing mice.
    General pharmacology, 1996, Volume: 27, Issue:8

    Topics: Animals; Carcinoma, Ehrlich Tumor; Cysteine; Female; Liver; Mice; Sulfhydryl Compounds; Thiazoles

1996
Utilization of cysteine and cysteine precursors for the synthesis of glutathione in astroglial cultures: preference for cystine.
    Glia, 1998, Volume: 22, Issue:1

    Topics: Animals; Astrocytes; Brain; Brain Chemistry; Cell Survival; Cells, Cultured; Cystathionine; Cysteine; Cystine; gamma-Glutamyltransferase; Glutathione; Methionine; Nerve Tissue Proteins; Pyrrolidonecarboxylic Acid; Rats; Rats, Wistar; Thiazoles; Thiazolidines

1998
Study of the metabolism of spiramycin in pig liver.
    Journal of chromatography. B, Biomedical sciences and applications, 1997, Dec-19, Volume: 704, Issue:1-2

    Topics: Acetonitriles; Animals; Anti-Bacterial Agents; Biotransformation; Chromatography, High Pressure Liquid; Cyclization; Cysteine; False Negative Reactions; Hydrogen-Ion Concentration; Hydrolysis; Liver; Magnetic Resonance Spectroscopy; Molecular Weight; Spiramycin; Swine; Thiazoles

1997
Role of glutathione in protection against noise-induced hearing loss.
    Brain research, 1998, Feb-16, Volume: 784, Issue:1-2

    Topics: Animals; Antioxidants; Auditory Threshold; Buthionine Sulfoximine; Chromatography, High Pressure Liquid; Cochlea; Cysteine; Evoked Potentials, Auditory, Brain Stem; Female; Glutathione; Guinea Pigs; Hearing Loss, Noise-Induced; Prodrugs; Pyrrolidonecarboxylic Acid; Thiazoles; Thiazolidines

1998
2-Methyl-thiazolidine-2,4-dicarboxylic acid protects against paracetamol induced toxicity in human liver derived HepG2 cells.
    Acta biochimica Polonica, 1997, Volume: 44, Issue:4

    Topics: Acetaminophen; Antidotes; Benzoquinones; Cell Line; Cysteine; Glutathione; Humans; Imines; Liver; Malondialdehyde; Oxidation-Reduction; Prodrugs; Reactive Oxygen Species; Thiazoles; Thiazolidines

1997
The effect of (L)-cysteine and (L)-2-oxothiazolidine-4-carboxylic acid (OTZ) on urinary oxalate excretion: studies using a hyperoxaluric rat model.
    The Journal of urology, 1998, Volume: 159, Issue:6

    Topics: Animals; Cysteine; Disease Models, Animal; Male; Oxalates; Pyrrolidonecarboxylic Acid; Rats; Rats, Inbred Strains; Thiazoles; Thiazolidines; Urinary Calculi

1998
Mice's brain radioprotection: comparative efficacy of a series of aminothiols and aminothiol precursors.
    Farmaco (Societa chimica italiana : 1989), 1997, Volume: 52, Issue:12

    Topics: Amifostine; Animals; Brain; Cysteamine; Cysteine; Female; Gamma Rays; Mice; Mice, Inbred C57BL; Radiation-Protective Agents; Sulfhydryl Compounds; Thiazoles

1997
Mice's rectum radioprotection: comparative efficacy of a series of aminothiols and aminothiol precursors.
    Farmaco (Societa chimica italiana : 1989), 1997, Volume: 52, Issue:12

    Topics: Amifostine; Animals; Cysteamine; Cysteine; Female; Gamma Rays; Mice; Mice, Inbred C57BL; Radiation-Protective Agents; Rectum; Sulfhydryl Compounds; Thiazoles

1997
The nonribosomal peptide synthetase HMWP2 forms a thiazoline ring during biogenesis of yersiniabactin, an iron-chelating virulence factor of Yersinia pestis.
    Biochemistry, 1998, Aug-18, Volume: 37, Issue:33

    Topics: Adenosine Monophosphate; Bacterial Outer Membrane Proteins; Bacterial Proteins; Carrier Proteins; Catalysis; Cysteine; Iron; Iron-Binding Proteins; Peptide Fragments; Peptide Synthases; Periplasmic Binding Proteins; Phenols; Protein Structure, Tertiary; Siderophores; Thiazoles; Virulence; Yersinia pestis

1998
Pharmacokinetics of 2-oxothiazolidine-4-carboxylate, a cysteine prodrug, and cysteine.
    Journal of clinical pharmacology, 1998, Volume: 38, Issue:10

    Topics: Adult; Cysteine; Glutathione; Humans; Infusions, Intravenous; Male; Prodrugs; Pyrrolidonecarboxylic Acid; Thiazoles; Thiazolidines

1998
3-(5-Dimethylamino-1-naphthalenesulphonyl)-2-(3-pyridyl)thiazolidine (YHI-1) selectively inhibits human immunodeficiency virus type 1.
    Antiviral chemistry & chemotherapy, 1998, Volume: 9, Issue:5

    Topics: Animals; Anti-HIV Agents; Antiviral Agents; Cell Line; Cysteine; Drug Resistance; Fishes; HIV Core Protein p24; HIV Protease; HIV-1; Humans; Molecular Structure; Naphthalenes; Nevirapine; Reverse Transcriptase Inhibitors; Thiazoles; Thiazolidines; Virus Replication

1998
N-acetylcysteine, but not methionine or 2-oxothiazolidine-4-carboxylate, serves as cysteine donor for the synthesis of glutathione in cultured neurons derived from embryonal rat brain.
    Neuroscience letters, 1999, Jan-08, Volume: 259, Issue:2

    Topics: Acetylcysteine; Animals; Brain; Cells, Cultured; Cysteine; Female; Glutathione; Methionine; Neurons; Pregnancy; Pyrrolidonecarboxylic Acid; Rats; Rats, Wistar; Thiazoles; Thiazolidines

1999
L-764406 is a partial agonist of human peroxisome proliferator-activated receptor gamma. The role of Cys313 in ligand binding.
    The Journal of biological chemistry, 1999, Mar-19, Volume: 274, Issue:12

    Topics: Amino Acid Sequence; Animals; Binding Sites; COS Cells; Cysteine; Humans; Kinetics; Ligands; Mass Spectrometry; Molecular Sequence Data; Protein Conformation; Quinoxalines; Receptors, Cytoplasmic and Nuclear; Structure-Activity Relationship; Thiazoles; Thiazolidinediones; Transcription Factors

1999
Inhibition of p56(lck) tyrosine kinase by isothiazolones.
    Archives of biochemistry and biophysics, 1999, Apr-01, Volume: 364, Issue:1

    Topics: Adenosine Triphosphate; Amino Acid Sequence; Animals; Binding Sites; Catalysis; Cell Line; Cysteine; Dose-Response Relationship, Drug; Enzyme Inhibitors; Humans; Jurkat Cells; Lymphocyte Activation; Lymphocyte Specific Protein Tyrosine Kinase p56(lck); Molecular Sequence Data; Phosphorylation; Receptors, Antigen, T-Cell; Signal Transduction; Sulfhydryl Compounds; Thiazoles; Time Factors

1999
Tandem heterocyclization activity of the multidomain 230 kDa HMWP2 subunit of Yersinia pestis yersiniabactin synthetase: interaction of the 1-1382 and 1383-2035 fragments.
    Biochemistry, 1999, Oct-19, Volume: 38, Issue:42

    Topics: Acyl Carrier Protein; Amino Acid Sequence; Bacterial Outer Membrane Proteins; Bacterial Proteins; Carrier Proteins; Catalysis; Cloning, Molecular; Cysteine; Dithiothreitol; Iron-Binding Proteins; Molecular Sequence Data; Mutagenesis, Site-Directed; Peptide Fragments; Periplasmic Binding Proteins; Phenols; Protein Structure, Tertiary; Siderophores; Substrate Specificity; Sulfhydryl Compounds; Thiazoles; Yersinia pestis

1999
[Application of ring-chain tautomerism for the development of prodrugs].
    Acta pharmaceutica Hungarica, 1999, Volume: 69, Issue:4

    Topics: Cysteine; Drug Design; Ephedrine; Hydrocortisone; Molecular Structure; Oxazoles; Prodrugs; Stereoisomerism; Thiazoles

1999
Assembly of the Pseudomonas aeruginosa nonribosomal peptide siderophore pyochelin: In vitro reconstitution of aryl-4, 2-bisthiazoline synthetase activity from PchD, PchE, and PchF.
    Biochemistry, 1999, Nov-09, Volume: 38, Issue:45

    Topics: Adenosine Triphosphate; Bacterial Proteins; Catalysis; Chromatography, High Pressure Liquid; Cysteine; Diphosphates; Iron Chelating Agents; Pantothenic Acid; Peptide Synthases; Phenols; Protein Processing, Post-Translational; Pseudomonas aeruginosa; Salicylates; Siderophores; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Thiazoles

1999
L-2-[(13)C]oxothiazolidine-4-carboxylic acid: a probe for precursor mobilization for glutathione synthesis.
    American journal of physiology. Endocrinology and metabolism, 2000, Volume: 278, Issue:1

    Topics: Acetaminophen; Adult; Aged; Breath Tests; Calorimetry, Indirect; Carbon Dioxide; Cysteine; Female; Glutathione; Humans; Kinetics; Male; Middle Aged; Models, Biological; Prodrugs; Pyrrolidonecarboxylic Acid; Thiazoles; Thiazolidines

2000
Comparison of N-acetylcysteine and l-2-oxothiazolidine-4-carboxylate as cysteine deliverers and glutathione precursors in human malignant melanoma transplants in mice.
    Cancer chemotherapy and pharmacology, 2000, Volume: 45, Issue:3

    Topics: Acetylcysteine; Animals; Buthionine Sulfoximine; Cysteine; Cysteinyldopa; Enzyme Inhibitors; Glutathione; Humans; Melanoma; Melanoma, Experimental; Mice; Mice, Nude; Microdialysis; Neoplasm Transplantation; Protein Precursors; Pyrrolidonecarboxylic Acid; Thiazoles; Thiazolidines; Transplantation, Heterologous; Tumor Cells, Cultured

2000
Selectivity of the yersiniabactin synthetase adenylation domain in the two-step process of amino acid activation and transfer to a holo-carrier protein domain.
    Biochemistry, 2000, Mar-07, Volume: 39, Issue:9

    Topics: Acylation; Adenosine Triphosphate; Bacterial Outer Membrane Proteins; Bacterial Proteins; Carrier Proteins; Cloning, Molecular; Coenzyme A; Cysteine; Diphosphates; Holoenzymes; Iron-Binding Proteins; Pantetheine; Peptide Fragments; Peptide Synthases; Periplasmic Binding Proteins; Phenols; Protein Structure, Tertiary; Siderophores; Substrate Specificity; Thiazoles; Thiolester Hydrolases; Transfer RNA Aminoacylation; Yersinia pestis

2000
Cysteine chloromethyl and diazomethyl ketone derivatives with potent anti-leukemic activity.
    Bioorganic & medicinal chemistry letters, 2000, Mar-20, Volume: 10, Issue:6

    Topics: Amino Acid Chloromethyl Ketones; Antineoplastic Agents; Cell Line; Coloring Agents; Cysteine; Humans; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured; Tumor Suppressor Protein p53

2000
Effects of L-2-oxothiazolidine-4-carboxylate on the cytotoxic activity and toxicity of cyclophosphamide in mice bearing B16F10 melanoma liver metastases.
    Melanoma research, 2000, Volume: 10, Issue:2

    Topics: Acrolein; Alkylation; Animals; Antineoplastic Agents, Alkylating; Biotransformation; Cell Division; Cyclophosphamide; Cysteine; Disease Progression; Drug Interactions; Drug Screening Assays, Antitumor; Female; Glutathione; Leukopenia; Liver Neoplasms; Melanoma, Experimental; Mice; Mice, Inbred C57BL; Oxidation-Reduction; Prodrugs; Pyrrolidonecarboxylic Acid; Thiazoles; Thiazolidines

2000
Enhanced expression of rat hepatic microsomal epoxide hydrolase by methylthiazole in conjunction with liver injury.
    Toxicology, 2000, May-05, Volume: 146, Issue:2-3

    Topics: Animals; Blotting, Northern; Chemical and Drug Induced Liver Injury; Cysteine; Densitometry; Dose-Response Relationship, Drug; Epoxide Hydrolases; Male; Methionine; Microsomes, Liver; Necrosis; Rats; Rats, Sprague-Dawley; RNA; Thiazoles

2000
Titanium(IV)-mediated tandem deprotection-cyclodehydration of protected cysteine N-amides: biomimetic syntheses of thiazoline- and thiazole-containing heterocycles.
    Organic letters, 2000, Oct-19, Volume: 2, Issue:21

    Topics: Amides; Crystallography, X-Ray; Cysteine; Heterocyclic Compounds; Molecular Mimicry; Molecular Structure; Thiazoles; Titanium

2000
Purification, priming, and catalytic acylation of carrier protein domains in the polyketide synthase and nonribosomal peptidyl synthetase modules of the HMWP1 subunit of yersiniabactin synthetase.
    Proceedings of the National Academy of Sciences of the United States of America, 2001, Jan-02, Volume: 98, Issue:1

    Topics: Acyl Carrier Protein; Acylation; Acyltransferases; Apoproteins; Bacillus subtilis; Bacterial Outer Membrane Proteins; Bacterial Proteins; Cloning, Molecular; Cysteine; Escherichia coli; Holoenzymes; Iron-Binding Proteins; Kinetics; Malonyl Coenzyme A; Molecular Structure; Molecular Weight; Multienzyme Complexes; Pantetheine; Peptide Fragments; Peptide Synthases; Periplasmic Binding Proteins; Phenols; Protein Processing, Post-Translational; Protein Structure, Tertiary; Protein Subunits; Recombinant Proteins; Siderophores; Thiazoles; Yersinia pestis

2001
Prevention of acetaminophen-induced liver toxicity by 2(R,S)-n-propylthiazolidine-4(R)-carboxylic acid in mice.
    Biochemical pharmacology, 2001, Jan-15, Volume: 61, Issue:2

    Topics: Acetaminophen; Aldehydes; Analgesics, Non-Narcotic; Animals; Chemical and Drug Induced Liver Injury; Cysteine; Dose-Response Relationship, Drug; Drug Interactions; Glutathione; Glutathione Disulfide; Liver; Liver Diseases; Male; Mice; Mice, Inbred C57BL; Prodrugs; Protective Agents; Thiazoles

2001
Effects of 2(RS)-n-propylthiazolidine-4(R)-carboxylic acid on extrahepatic sulfhydryl levels in mice treated with acetaminophen.
    Biochemical pharmacology, 2001, Apr-01, Volume: 61, Issue:7

    Topics: Acetaminophen; Analgesics, Non-Narcotic; Animals; Brain; Cysteine; Drug Interactions; Glutathione; Hepatocytes; In Vitro Techniques; Kidney Cortex; Male; Mice; Mice, Inbred C57BL; Prodrugs; Sulfhydryl Compounds; Thiazoles; Tissue Distribution

2001
Enhanced potency of human Sonic hedgehog by hydrophobic modification.
    Biochemistry, 2001, Apr-10, Volume: 40, Issue:14

    Topics: Acyl Coenzyme A; Amides; Amino Acid Substitution; Animals; Cell Line; Circular Dichroism; Cysteine; Ethylmaleimide; Fatty Acids; Formaldehyde; Hedgehog Proteins; Humans; Indicators and Reagents; Intracellular Signaling Peptides and Proteins; Iodoacetamide; Membrane Proteins; Mice; Mice, Inbred C3H; Patched Receptors; Peptide Fragments; Protein Binding; Protein Processing, Post-Translational; Proteins; Receptors, Cell Surface; Signal Transduction; Spectrometry, Mass, Electrospray Ionization; Sulfhydryl Compounds; Thiazoles; Thiazolidines; Trans-Activators; Up-Regulation

2001
Consequences of a modified putative substrate-activation site on catalysis by yeast pyruvate decarboxylase.
    Biochemistry, 2001, Feb-13, Volume: 40, Issue:6

    Topics: Alanine; Catalysis; Cysteine; Deuterium Oxide; Enzyme Activation; Hydrogen; Kinetics; Models, Chemical; Pyruvate Decarboxylase; Recombinant Proteins; Saccharomyces cerevisiae; Serine; Solvents; Substrate Specificity; Thiamine Pyrophosphate; Thiazoles

2001
Feedback control of the arachidonate cascade in rheumatoid synoviocytes by 15-deoxy-Delta(12,14)-prostaglandin J2.
    Biochemical and biophysical research communications, 2001, May-18, Volume: 283, Issue:4

    Topics: Arachidonic Acid; Arthritis, Rheumatoid; Chromans; Cyclooxygenase 2; Cysteine; Dinoprostone; Feedback; Humans; Isoenzymes; Leukotriene Antagonists; Leukotriene B4; Leukotrienes; Membrane Proteins; Prostaglandin D2; Prostaglandin-Endoperoxide Synthases; Receptors, Cytoplasmic and Nuclear; Synovial Membrane; Thiazoles; Thiazolidinediones; Transcription Factors; Troglitazone

2001
Thiazolidine prodrugs as protective agents against gamma-radiation-induced toxicity and mutagenesis in V79 cells.
    Journal of medicinal chemistry, 2001, Aug-02, Volume: 44, Issue:16

    Topics: Animals; Antimutagenic Agents; Cell Death; Cell Line; Cricetinae; Cricetulus; Cysteamine; Cysteine; Gamma Rays; Mercaptoethylamines; Mutagenicity Tests; Prodrugs; Radiation-Protective Agents; Structure-Activity Relationship; Sugar Alcohols; Thiazoles; Thiazolidines

2001
Antidiabetic effect of a prodrug of cysteine, L-2-oxothiazolidine-4-carboxylic acid, through CD38 dimerization and internalization.
    The Journal of biological chemistry, 2002, Feb-15, Volume: 277, Issue:7

    Topics: ADP-ribosyl Cyclase; ADP-ribosyl Cyclase 1; Animals; Antigens, CD; Antigens, Differentiation; Antioxidants; Blood Glucose; Calcium; Cell Line; Cell Separation; Cysteine; Dimerization; Disulfides; DNA, Complementary; Dose-Response Relationship, Drug; Flow Cytometry; Glucose; Green Fluorescent Proteins; HeLa Cells; Humans; Hypoglycemic Agents; Immunohistochemistry; Islets of Langerhans; Luminescent Proteins; Membrane Glycoproteins; Mice; Mice, Inbred BALB C; Microscopy, Confocal; Mutagenesis, Site-Directed; Mutation; NAD+ Nucleosidase; Oligonucleotides, Antisense; Pyrrolidonecarboxylic Acid; Signal Transduction; Thiazoles; Thiazolidines; Time Factors; Transfection

2002
Design, synthesis, and pharmacological evaluation of new farnesyl protein transferase inhibitors.
    Journal of medicinal chemistry, 2002, Jan-17, Volume: 45, Issue:2

    Topics: 3T3 Cells; Alkyl and Aryl Transferases; Animals; Cell Membrane Permeability; Cysteine; Enzyme Inhibitors; Imidazoles; Methionine; Mice; Models, Molecular; Molecular Mimicry; Peptides; Structure-Activity Relationship; Thiazoles

2002
Conformation of beta 2-microglobulin amyloid fibrils analyzed by reduction of the disulfide bond.
    The Journal of biological chemistry, 2002, Jun-14, Volume: 277, Issue:24

    Topics: Amyloid; Benzothiazoles; beta 2-Microglobulin; Chromatography, High Pressure Liquid; Circular Dichroism; Crystallography, X-Ray; Cysteine; Disulfides; Humans; Hydrogen-Ion Concentration; Microscopy, Electron; Models, Molecular; Protein Binding; Protein Conformation; Protein Folding; Recombinant Proteins; Spectrometry, Fluorescence; Thiazoles

2002
Dose-dependent cysteine-mediated protection of insulin-producing cells from damage by hydrogen peroxide.
    Biochemical pharmacology, 2002, Apr-01, Volume: 63, Issue:7

    Topics: Animals; Antioxidants; Apoptosis; Cell Survival; Coloring Agents; Cysteine; DNA; Dose-Response Relationship, Drug; Drug Interactions; Glutathione; Hydrogen Peroxide; Insulin; Islets of Langerhans; Protective Agents; Rats; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured

2002
Cysteinyl leukotriene-dependent interleukin-5 production leading to eosinophilia during late asthmatic response in guinea-pigs.
    Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology, 2002, Volume: 32, Issue:4

    Topics: Animals; Asthma; Cell Survival; Chromones; Cysteine; Eosinophilia; Guinea Pigs; Interleukin-5; Kinetics; Leukotriene Antagonists; Leukotrienes; Male; Membrane Proteins; Ovalbumin; Pulmonary Eosinophilia; Receptors, Leukotriene; Thiazoles

2002
Genes from Pseudomonas sp. strain BS involved in the conversion of L-2-amino-Delta(2)-thiazolin-4-carbonic acid to L-cysteine.
    Applied and environmental microbiology, 2002, Volume: 68, Issue:5

    Topics: Amino Acid Sequence; Bacterial Proteins; Base Sequence; Cloning, Molecular; Cysteine; DNA, Bacterial; Genes, Bacterial; Molecular Sequence Data; Open Reading Frames; Pseudomonas; Sequence Analysis, Protein; Sequence Homology, Amino Acid; Thiazoles

2002
Identification, cloning, and sequencing of the genes involved in the conversion of D,L-2-amino-delta2-thiazoline-4-carboxylic acid to L-cysteine in Pseudomonas sp. strain ON-4a.
    Bioscience, biotechnology, and biochemistry, 2002, Volume: 66, Issue:5

    Topics: Amino Acid Sequence; Cloning, Molecular; Cysteine; Electrophoresis, Polyacrylamide Gel; Escherichia coli; Molecular Sequence Data; Pseudomonas; Sequence Homology, Amino Acid; Thiazoles

2002
Highly specific inactivation of triosephosphate isomerase from Trypanosoma cruzi.
    Biochemical and biophysical research communications, 2002, Jul-26, Volume: 295, Issue:4

    Topics: Animals; Benzothiazoles; Cysteine; Dimerization; Dose-Response Relationship, Drug; Humans; Inhibitory Concentration 50; Models, Chemical; Protein Binding; Thiazoles; Triose-Phosphate Isomerase; Trypanosoma cruzi

2002
Induction of systemic resistance to Botrytis cinerea in tomato by Pseudomonas aeruginosa 7NSK2: role of salicylic acid, pyochelin, and pyocyanin.
    Molecular plant-microbe interactions : MPMI, 2002, Volume: 15, Issue:11

    Topics: Botrytis; Cysteine; Genetic Complementation Test; Immunity, Innate; Mutation; Phenols; Plant Diseases; Plant Roots; Pseudomonas aeruginosa; Pyocyanine; Salicylic Acid; Siderophores; Solanum lycopersicum; Thiazoles

2002
Identification and localization of the gene cluster encoding biosynthesis of the antitumor macrolactam leinamycin in Streptomyces atroolivaceus S-140.
    Journal of bacteriology, 2002, Volume: 184, Issue:24

    Topics: Amino Acid Sequence; Antibiotics, Antineoplastic; Chromosome Mapping; Cloning, Molecular; Cysteine; Genes, Bacterial; Lactams; Macrolides; Molecular Sequence Data; Multienzyme Complexes; Multigene Family; Peptide Synthases; Polymerase Chain Reaction; Streptomyces; Thiazoles; Thiones

2002
Coupling of contact sensitizers to thiol groups is a key event for the activation of monocytes and monocyte-derived dendritic cells.
    The Journal of investigative dermatology, 2003, Volume: 120, Issue:2

    Topics: Acetates; Anti-Infective Agents; Antioxidants; Cysteine; Dendritic Cells; Ethylmaleimide; Humans; Interleukin-1; Lysine; Maleimides; MAP Kinase Signaling System; Monocytes; Phosphorylation; Picryl Chloride; Succinimides; Sulfhydryl Compounds; Sulfhydryl Reagents; Thiazoles; Tyrosine

2003
Structure-activity study of L-amino acid-based N-type calcium channel blockers.
    Bioorganic & medicinal chemistry, 2003, Apr-17, Volume: 11, Issue:8

    Topics: Amino Acids; Animals; Calcium; Calcium Channel Blockers; Calcium Channels, L-Type; Calcium Channels, N-Type; Cysteine; Electrophysiology; Humans; Inhibitory Concentration 50; Mice; Neuroblastoma; Structure-Activity Relationship; Thiazoles; Tumor Cells, Cultured

2003
Synthesis and collateral dilator activity of nitroxyalkylamides having direct or latent sulfhydryl moieties.
    Bioorganic & medicinal chemistry letters, 2003, May-05, Volume: 13, Issue:9

    Topics: Animals; Area Under Curve; Carotid Arteries; Collateral Circulation; Cysteine; Dogs; Drug Tolerance; Injections, Intravenous; Male; Nitrates; Nitric Oxide Donors; Nitroglycerin; Sulfhydryl Compounds; Thiazoles; Vasodilator Agents

2003
Ascorbate, added after irradiation, reduces the mutant yield and alters the spectrum of CD59- mutations in A(L) cells irradiated with high LET carbon ions.
    Journal of radiation research, 2002, Volume: 43 Suppl

    Topics: Animals; Ascorbic Acid; Carbon; CD59 Antigens; Cricetinae; Cysteine; Free Radical Scavengers; Humans; Hybrid Cells; Ions; Linear Energy Transfer; Mutation; Thiazoles; Thiazolidines

2002
BlmIII and BlmIV nonribosomal peptide synthetase-catalyzed biosynthesis of the bleomycin bithiazole moiety involving both in cis and in trans aminoacylation.
    Biochemistry, 2003, Aug-19, Volume: 42, Issue:32

    Topics: Acylation; Amino Acid Motifs; Amino Acid Sequence; Bleomycin; Cloning, Molecular; Consensus Sequence; Cysteine; Escherichia coli Proteins; Molecular Sequence Data; Peptide Synthases; Protein Structure, Tertiary; Protein Subunits; Recombinant Proteins; Repetitive Sequences, Amino Acid; Stereoisomerism; Thiazoles

2003
Epimerization of an L-cysteinyl to a D-cysteinyl residue during thiazoline ring formation in siderophore chain elongation by pyochelin synthetase from Pseudomonas aeruginosa.
    Biochemistry, 2003, Sep-09, Volume: 42, Issue:35

    Topics: Amino Acid Sequence; Bacterial Proteins; Cysteine; Ligases; Molecular Conformation; Molecular Sequence Data; Molecular Structure; Phenols; Protein Subunits; Pseudomonas aeruginosa; Sequence Alignment; Siderophores; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Thiazoles

2003
N-formylcysteine synthesis in mitochondria from formaldehyde and L-cysteine via thiazolidinecarboxylic acid.
    The Journal of biological chemistry, 1957, Volume: 227, Issue:1

    Topics: Cysteine; Formaldehyde; Liver; Mitochondria; Thiazoles; Thiazolidines

1957
Thiazoline carboxylic acid from formylcysteine.
    Experientia, 1957, Nov-15, Volume: 13, Issue:11

    Topics: Carboxylic Acids; Cysteine; Thiazoles

1957
A NEW metabolite of cysteine.
    Nutrition reviews, 1958, Volume: 16, Issue:3

    Topics: Cysteine; Humans; Thiazoles

1958
2-Thiazolidinethione-4-carboxylic acid from the reaction of captan with cysteine.
    Science (New York, N.Y.), 1958, Mar-21, Volume: 127, Issue:3299

    Topics: Antifungal Agents; Captan; Carboxylic Acids; Cysteine; Fungicides, Industrial; Thiazoles; Thiazolidines

1958
[Thiazolidine-carboxylic acid, iminothiazolidine-carboxylic acid and thiazane-carboxylic acid as liver protective substances in comparison with cysteine].
    Klinische Wochenschrift, 1958, Apr-15, Volume: 36, Issue:8

    Topics: Carboxylic Acids; Cysteine; Digestion; Humans; Liver; Thiazoles; Thiazolidines

1958
The replacement by thiazolidinecarboxylic acid of exogenous cystine and cysteine.
    The Journal of nutrition, 1958, Dec-10, Volume: 66, Issue:4

    Topics: Cysteine; Cystine; Humans; Thiazoles; Thiazolidines

1958
S-DEMETHYLATION BY MICROSOMAL ENZYMES.
    The Journal of pharmacology and experimental therapeutics, 1964, Volume: 143

    Topics: Barbiturates; Cysteine; Formaldehyde; Liver; Mercaptopurine; Metabolism; Methionine; Rats; Research; Sulfhydryl Compounds; Sulfides; Thiazoles

1964
SULPHUR NUTRITION OF TWO STRAINS OF THE YEAST, DEBARYOMYCES KLOECKERI, ISOLATED FROM SUBANTARCTIC SOIL.
    Canadian journal of microbiology, 1964, Volume: 10

    Topics: Amino Acids; Cold Climate; Culture Media; Cysteine; Cystine; Ethionine; Glutathione; Homocysteine; Mercaptoethylamines; Metabolism; Methionine; Research; Saccharomyces; Saccharomyces cerevisiae; Soil; Soil Microbiology; Sulfates; Sulfides; Sulfites; Sulfonic Acids; Sulfur; Thiamine; Thiazoles; Thioctic Acid; Thioglycolates; Thiosulfates

1964
The "pro-drug" RibCys decreases the mutagenicity of high-LET radiation in cultured mammalian cells.
    Radiation research, 2003, Volume: 160, Issue:5

    Topics: Animals; Carbon Radioisotopes; Cell Count; Cell Survival; CHO Cells; Cricetinae; Cricetulus; Cysteine; Dose-Response Relationship, Drug; Dose-Response Relationship, Radiation; Humans; Hybrid Cells; Iron Radioisotopes; Linear Energy Transfer; Lymphocytes; Mutation; Prodrugs; Radiation Dosage; Radiation Tolerance; Radiation-Protective Agents; Thiazoles; Thiazolidines

2003
Conversion of the aminocrotonate intermediate limits the rate of gamma-elimination reaction catalyzed by L-cystathionine gamma-lyase of the yeast Saccharomyces cerevisiae.
    Journal of biochemistry, 2003, Volume: 134, Issue:4

    Topics: Catalysis; Cystathionine gamma-Lyase; Cysteine; Dose-Response Relationship, Drug; Kinetics; Models, Chemical; Phosphates; Potassium Compounds; Saccharomyces cerevisiae; Spectrophotometry; Thiazoles; Time Factors

2003
Isolation and characterization of Burkholderia cenocepacia mutants deficient in pyochelin production: pyochelin biosynthesis is sensitive to sulfur availability.
    Journal of bacteriology, 2004, Volume: 186, Issue:2

    Topics: Burkholderia; Chromosome Mapping; Cysteine; DNA Transposable Elements; Methionine; Mutation; Phenols; Sulfur; Thiazoles

2004
Thiamine biosynthesis in Escherichia coli: in vitro reconstitution of the thiazole synthase activity.
    The Journal of biological chemistry, 2004, Apr-23, Volume: 279, Issue:17

    Topics: Adenosine; Bacterial Proteins; Carbon-Sulfur Lyases; Carrier Proteins; Cell-Free System; Chromatography, High Pressure Liquid; Culture Media; Cysteine; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Escherichia coli; Escherichia coli Proteins; Ligases; Models, Chemical; NADP; Nucleotidyltransferases; Plasmids; S-Adenosylmethionine; Sulfurtransferases; Thiamine; Thiazoles; Time Factors; Tyrosine

2004
Bovine 5-oxo-L-prolinase: simple assay method, purification, cDNA cloning, and detection of mRNA in the coronary artery.
    Biological & pharmaceutical bulletin, 2004, Volume: 27, Issue:3

    Topics: Amidohydrolases; Amino Acid Sequence; Animals; Cattle; Cloning, Molecular; Coronary Vessels; Cysteine; DNA, Complementary; Electrophoresis, Polyacrylamide Gel; Humans; In Vitro Techniques; Molecular Sequence Data; Nitrates; Pyrrolidonecarboxylic Acid; Rats; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sequence Homology, Amino Acid; Species Specificity; Thiazoles; Thiazolidines; Vasodilator Agents

2004
Direct photoaffinity labeling by dolastatin 10 of the amino-terminal peptide of beta-tubulin containing cysteine 12.
    The Journal of biological chemistry, 2004, Jul-16, Volume: 279, Issue:29

    Topics: Animals; Antineoplastic Agents; Binding Sites; Brain; Cattle; Computer Simulation; Cysteine; Depsipeptides; Dithiothreitol; Electrophoresis, Polyacrylamide Gel; Guanosine Diphosphate; Kinetics; Ligands; Light; Models, Chemical; Models, Molecular; Oligopeptides; Peptides; Peptides, Cyclic; Photoaffinity Labels; Protein Binding; Protein Conformation; Protein Structure, Tertiary; Thiazoles; Time Factors; Tubulin; Ultraviolet Rays

2004
A one-pot total synthesis of crambin.
    Angewandte Chemie (International ed. in English), 2004, May-03, Volume: 43, Issue:19

    Topics: Amino Acid Sequence; Chromatography, High Pressure Liquid; Crystallography, X-Ray; Cysteine; Gas Chromatography-Mass Spectrometry; Models, Molecular; Molecular Sequence Data; Nuclear Magnetic Resonance, Biomolecular; Peptides; Plant Proteins; Protein Conformation; Protein Folding; Thiazoles; Thiazolidines

2004
A role for long-lived radicals (LLR) in radiation-induced mutation and persistent chromosomal instability: counteraction by ascorbate and RibCys but not DMSO.
    Mutation research, 2004, Jul-13, Volume: 551, Issue:1-2

    Topics: Animals; Ascorbic Acid; Carbon; CD59 Antigens; Chromosomal Instability; Cricetinae; Cricetulus; Cysteine; Dimethyl Sulfoxide; Humans; Hybrid Cells; Hypoxanthine Phosphoribosyltransferase; Linear Energy Transfer; Mutation; Radiation-Protective Agents; Thiazoles; Thiazolidines

2004
p-Aminophenol-induced hepatotoxicity in hamsters: role of glutathione.
    Journal of biochemical and molecular toxicology, 2004, Volume: 18, Issue:3

    Topics: Alanine Transaminase; Aminophenols; Animals; Chromatography, High Pressure Liquid; Cricetinae; Cysteine; Dose-Response Relationship, Drug; Drug Interactions; Drug-Related Side Effects and Adverse Reactions; Glutathione; Kinetics; L-Iditol 2-Dehydrogenase; Liver; Male; Methemoglobinemia; Protective Agents; Thiazoles

2004
Determination of cysteine concentration by fluorescence increase: reaction of cysteine with a fluorogenic aldehyde.
    Chemical communications (Cambridge, England), 2004, Aug-07, Issue:15

    Topics: Aldehydes; Amino Acids; Cysteine; Fluorescent Dyes; Thiazoles

2004
PchC thioesterase optimizes nonribosomal biosynthesis of the peptide siderophore pyochelin in Pseudomonas aeruginosa.
    Journal of bacteriology, 2004, Volume: 186, Issue:19

    Topics: Aminobutyrates; Bacterial Proteins; Cysteine; Phenols; Pseudomonas aeruginosa; Thiazoles

2004
Dendritic macromers as in situ polymerizing biomaterials for securing cataract incisions.
    Journal of the American Chemical Society, 2004, Oct-13, Volume: 126, Issue:40

    Topics: Biocompatible Materials; Cataract Extraction; Cysteine; Hydrogels; Peptides; Polyethylene Glycols; Thiazoles

2004
An intersheet packing interaction in A beta fibrils mapped by disulfide cross-linking.
    Biochemistry, 2004, Dec-14, Volume: 43, Issue:49

    Topics: Amino Acid Sequence; Amyloid beta-Peptides; Antibodies, Monoclonal; Benzothiazoles; Cross-Linking Reagents; Cysteine; Disulfides; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Oxidation-Reduction; Peptide Fragments; Peptide Mapping; Protein Structure, Secondary; Spectrometry, Fluorescence; Thiazoles

2004
Palmitoylated cysteine 192 is required for RhoB tumor-suppressive and apoptotic activities.
    The Journal of biological chemistry, 2005, May-13, Volume: 280, Issue:19

    Topics: Alanine; Amino Acid Sequence; Apoptosis; Blotting, Western; Cell Cycle Proteins; Cell Line; Cell Line, Tumor; Cell Proliferation; Coloring Agents; Cyclin-Dependent Kinase Inhibitor p21; Cysteine; DNA Primers; Genes, Tumor Suppressor; Glycine; Humans; In Situ Nick-End Labeling; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; Palmitic Acid; Promoter Regions, Genetic; Protein Biosynthesis; Protein Prenylation; rhoA GTP-Binding Protein; rhoB GTP-Binding Protein; Sequence Homology, Amino Acid; Serine; Tetrazolium Salts; Thiazoles; Transcription Factor AP-1; Transcription, Genetic; Transfection; Transforming Growth Factor beta

2005
The hair growth promoting effect of Asiasari radix extract and its molecular regulation.
    Journal of dermatological science, 2005, Volume: 38, Issue:2

    Topics: Alopecia; Animals; Cell Proliferation; Cell Survival; Cholestenone 5 alpha-Reductase; Cysteine; DNA Primers; Female; Hair; Hair Follicle; Humans; Keratinocytes; Mice; Mice, Inbred C3H; Mice, Inbred C57BL; Plant Extracts; Plant Preparations; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Skin; Tetrazolium Salts; Thiazoles; Thymidine; Time Factors; Vibrissae

2005
Molybdenum oxides as highly effective dehydrative cyclization catalysts for the synthesis of oxazolines and thiazolines.
    Organic letters, 2005, May-12, Volume: 7, Issue:10

    Topics: Catalysis; Cyclization; Cysteine; Molybdenum; Oxazoles; Serine; Thiazoles; Threonine

2005
Effect of ribose cysteine pretreatment on hepatic and renal acetaminophen metabolite formation and glutathione depletion.
    Basic & clinical pharmacology & toxicology, 2005, Volume: 96, Issue:6

    Topics: Acetaminophen; Animals; Blood Urea Nitrogen; Buthionine Sulfoximine; Chemical and Drug Induced Liver Injury; Cysteine; Glutathione; In Vitro Techniques; Kidney; Kidney Diseases; L-Iditol 2-Dehydrogenase; Liver; Liver Diseases; Male; Mice; Mice, Inbred Strains; Microsomes, Liver; Prodrugs; Protective Agents; Thiazoles; Thiazolidines

2005
Arabidopsis AtDGK7, the smallest member of plant diacylglycerol kinases (DGKs), displays unique biochemical features and saturates at low substrate concentration: the DGK inhibitor R59022 differentially affects AtDGK2 and AtDGK7 activity in vitro and alte
    The Journal of biological chemistry, 2005, Oct-14, Volume: 280, Issue:41

    Topics: Adenosine Triphosphate; Amino Acid Sequence; Arabidopsis; Bacteria; Blotting, Western; Chromatography, High Pressure Liquid; Cloning, Molecular; Cysteine; Detergents; Diacylglycerol Kinase; Diglycerides; DNA, Complementary; Dose-Response Relationship, Drug; Enzyme Inhibitors; Escherichia coli; Gene Expression Regulation, Plant; Genome, Plant; Glycerol; Hydrogen-Ion Concentration; Kinetics; Models, Genetic; Molecular Sequence Data; Multigene Family; Oleic Acids; Phosphatidic Acids; Plant Proteins; Plant Roots; Protein Structure, Tertiary; Pyrimidinones; Recombinant Proteins; Reverse Transcriptase Polymerase Chain Reaction; Sequence Homology, Amino Acid; Signal Transduction; Substrate Specificity; Thiazoles; Time Factors

2005
Scanning cysteine mutagenesis analysis of Abeta-(1-40) amyloid fibrils.
    The Journal of biological chemistry, 2006, Jan-13, Volume: 281, Issue:2

    Topics: Amino Acid Sequence; Amyloid beta-Peptides; Benzothiazoles; Chromatography, High Pressure Liquid; Cysteine; Cystine; Electron Spin Resonance Spectroscopy; Humans; Hydrocarbons, Iodinated; Iodoacetic Acid; Kinetics; Microscopy, Electron; Models, Molecular; Molecular Sequence Data; Mutagenesis; Mutation; Peptide Fragments; Peptide Mapping; Peptides; Protein Binding; Protein Conformation; Protein Structure, Secondary; Protein Structure, Tertiary; Solvents; Thermodynamics; Thiazoles; Time Factors

2006
Detection of homocysteine and cysteine.
    Journal of the American Chemical Society, 2005, Nov-16, Volume: 127, Issue:45

    Topics: Aldehydes; Chromatography, High Pressure Liquid; Colorimetry; Cysteine; Fluorescent Dyes; Homocysteine; Humans; Peptides; Spectrometry, Fluorescence; Sulfhydryl Compounds; Thiazoles; Transition Elements

2005
Alpha-thiolamines such as cysteine and cysteamine act as effective transglycating agents due to formation of irreversible thiazolidine derivatives.
    Medical hypotheses, 2006, Volume: 66, Issue:4

    Topics: Cysteamine; Cysteine; Glucose; Glycosylation; Thiazoles

2006
Aromatic interactions with phenylalanine 691 and cysteine 828: a concept for FMS-like tyrosine kinase-3 inhibition. Application to the discovery of a new class of potential antileukemia agents.
    Journal of medicinal chemistry, 2006, Jul-27, Volume: 49, Issue:15

    Topics: Acute Disease; Adenosine Triphosphate; Antineoplastic Agents; Binding Sites; Cell Line, Tumor; Cysteine; fms-Like Tyrosine Kinase 3; Humans; Leukemia, Myeloid; Models, Molecular; Mutation; Phenylalanine; Protein Structure, Tertiary; Thiazoles

2006
Cloning, expression, and identification of genes involved in the conversion of DL-2-amino-Delta2-thiazoline-4-carboxylic acid to L-cysteine via S-carbamyl-L-cysteine pathway in Pseudomonas sp. TS1138.
    Bioscience, biotechnology, and biochemistry, 2006, Volume: 70, Issue:9

    Topics: Base Sequence; Chromatography, Thin Layer; Cloning, Molecular; Cysteine; DNA, Bacterial; Electrophoresis, Polyacrylamide Gel; Gene Library; Genes, Bacterial; Industrial Microbiology; Molecular Sequence Data; Pseudomonas; Recombinant Proteins; Sequence Analysis, DNA; Thiazoles

2006
Synthesis and antiviral property of allophenylnorstatine-based HIV protease inhibitors incorporating D-cysteine derivatives as P2/P3 moieties.
    Bioorganic & medicinal chemistry letters, 2007, Aug-01, Volume: 17, Issue:15

    Topics: Amides; Cell Line; Cysteine; HIV; HIV Protease Inhibitors; Humans; Models, Molecular; Phenylbutyrates; Thiazoles

2007
Total anti-oxidant capacity of cell culture media.
    Clinical and experimental pharmacology & physiology, 2007, Volume: 34, Issue:8

    Topics: Antioxidants; Benzothiazoles; Chlorides; Colorimetry; Culture Media; Cysteine; Ferric Compounds; Oxidation-Reduction; Phenolsulfonphthalein; Spectrophotometry; Sulfonic Acids; Thiazoles; Tryptophan; Tyrosine

2007
The active site cysteine of the proapoptotic protein glyceraldehyde-3-phosphate dehydrogenase is essential in oxidative stress-induced aggregation and cell death.
    The Journal of biological chemistry, 2007, Sep-07, Volume: 282, Issue:36

    Topics: Amino Acid Substitution; Amyloid; Animals; Apoptosis Regulatory Proteins; Benzothiazoles; Binding Sites; Cell Death; Cysteine; Glyceraldehyde-3-Phosphate Dehydrogenases; HeLa Cells; Humans; Mutation, Missense; Neurons; Oxidants; Oxidation-Reduction; Oxidative Stress; Protein Structure, Secondary; Rabbits; Thiazoles

2007
Comparative efficacies of 2 cysteine prodrugs and a glutathione delivery agent in a colitis model.
    Translational research : the journal of laboratory and clinical medicine, 2007, Volume: 150, Issue:2

    Topics: Animals; Colitis; Colon; Cysteine; Dextran Sulfate; Drug Delivery Systems; Glutathione; Interleukin-12; Interleukin-6; Male; Mice; Mice, Inbred ICR; Sucrose; Thiazoles; Thiazolidines; Up-Regulation

2007
Reactive sulfur species: kinetics and mechanism of the hydrolysis of cysteine thiosulfinate ester.
    Chemical research in toxicology, 2007, Volume: 20, Issue:9

    Topics: Cysteine; Disulfides; Hydrogen-Ion Concentration; Hydrolysis; Kinetics; Lactams; Macrolides; Molecular Structure; Oxidation-Reduction; Sulfinic Acids; Sulfur; Thiazoles; Thiones; Thiosulfonic Acids

2007
Pseudomonas fluorescens CHA0 produces enantio-pyochelin, the optical antipode of the Pseudomonas aeruginosa siderophore pyochelin.
    The Journal of biological chemistry, 2007, Dec-07, Volume: 282, Issue:49

    Topics: Cysteine; Gene Expression Regulation, Bacterial; Isomerism; Molecular Structure; Phenols; Pseudomonas aeruginosa; Pseudomonas fluorescens; Salicylic Acid; Siderophores; Thiazoles

2007
Anti-amyloidogenic activity of S-allyl-L-cysteine and its activity to destabilize Alzheimer's beta-amyloid fibrils in vitro.
    Neuroscience letters, 2007, Dec-18, Volume: 429, Issue:2-3

    Topics: Alzheimer Disease; Amyloid beta-Peptides; Antioxidants; Benzothiazoles; Cysteine; Humans; Macromolecular Substances; Microscopy, Electron, Transmission; Neuroprotective Agents; Protein Binding; Protein Conformation; Protein Folding; Thiazoles

2007
Overexpression of yeast S-adenosylmethionine synthetase metK in Streptomyces actuosus leads to increased production of nosiheptide.
    Applied microbiology and biotechnology, 2008, Volume: 78, Issue:6

    Topics: Cysteine; Gene Expression; Genetic Engineering; Industrial Microbiology; Methionine Adenosyltransferase; S-Adenosylmethionine; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Streptomyces; Thiazoles

2008
The immobilization of animal cells using the cysteine-modified RGD oligopeptide.
    Ultramicroscopy, 2008, Volume: 108, Issue:10

    Topics: Amino Acid Sequence; Animals; Cell Division; Cell Survival; Cells; Cells, Immobilized; Cysteine; HeLa Cells; Humans; Image Processing, Computer-Assisted; Microscopy; Microscopy, Atomic Force; Oligopeptides; Tetrazolium Salts; Thiazoles

2008
Biosynthetic origin of BE-10988 in Streptomyces sp. BA10988.
    The Journal of organic chemistry, 2008, Jul-18, Volume: 73, Issue:14

    Topics: Cysteine; Glucose; Magnetic Resonance Spectroscopy; Molecular Structure; Spectrometry, Mass, Electrospray Ionization; Streptomyces; Thiazoles; Tryptophan

2008
The methylmercury-L-cysteine conjugate is a substrate for the L-type large neutral amino acid transporter.
    Journal of neurochemistry, 2008, Volume: 107, Issue:4

    Topics: Analysis of Variance; Animals; Carbon Isotopes; Cell Survival; CHO Cells; Cricetinae; Cricetulus; Cysteine; Humans; L-Lactate Dehydrogenase; Large Neutral Amino Acid-Transporter 1; Methylmercury Compounds; RNA, Small Interfering; Tetrazolium Salts; Thiazoles; Transfection

2008
Dietary supplementation with resveratrol reduces plaque pathology in a transgenic model of Alzheimer's disease.
    Neurochemistry international, 2009, Volume: 54, Issue:2

    Topics: Alzheimer Disease; Animals; Antioxidants; Ascorbic Acid; Benzothiazoles; Blotting, Western; Brain; Cerebral Ventricles; Cysteine; Dietary Supplements; Female; Glutathione; Hippocampus; Humans; Immunohistochemistry; Male; Mice; Mice, Transgenic; Plaque, Amyloid; Resveratrol; Sirtuin 1; Sirtuins; Stilbenes; tau Proteins; Thiazoles; Transcription Factors; Tumor Suppressor Protein p53

2009
Dopamine auto-oxidation aggravates non-apoptotic cell death induced by over-expression of human A53T mutant alpha-synuclein in dopaminergic PC12 cells.
    Journal of neurochemistry, 2009, Volume: 108, Issue:3

    Topics: Acetylcysteine; alpha-Synuclein; Animals; Benzimidazoles; Cell Death; Chromatography, High Pressure Liquid; Cysteine; Dopamine; Enzyme Inhibitors; Flow Cytometry; Fluorescent Dyes; Free Radical Scavengers; Glutathione; Humans; Monophenol Monooxygenase; Mutation; Nerve Growth Factor; Oxidation-Reduction; PC12 Cells; Rats; Tetrazolium Salts; Thiazoles; Transfection

2009
Aggregate formation and toxicity by wild-type and R621C synphilin-1 in the nigrostriatal system of mice using adenoviral vectors.
    Journal of neurochemistry, 2009, Volume: 108, Issue:1

    Topics: Adenoviridae; Animals; Arginine; Benzothiazoles; Carrier Proteins; Corpus Striatum; Cysteine; Gene Expression; Genetic Vectors; Green Fluorescent Proteins; Intracellular Signaling Peptides and Proteins; Mice; Mice, Inbred C57BL; Mice, Transgenic; Mutation; Nerve Degeneration; Nerve Tissue Proteins; Substantia Nigra; Thiazoles; Tyrosine 3-Monooxygenase

2009
A glucosinolate metabolism pathway in living plant cells mediates broad-spectrum antifungal defense.
    Science (New York, N.Y.), 2009, Jan-02, Volume: 323, Issue:5910

    Topics: Arabidopsis; Arabidopsis Proteins; Ascomycota; Cysteine; Cytochrome P-450 Enzyme System; Genes, Plant; Glucosinolates; Glycoside Hydrolases; Indoles; Metabolic Networks and Pathways; Mutation; N-Glycosyl Hydrolases; Plant Diseases; Thiazoles; Thiones; Tryptophan

2009
A critical cysteine residue in monoacylglycerol lipase is targeted by a new class of isothiazolinone-based enzyme inhibitors.
    British journal of pharmacology, 2009, Volume: 157, Issue:6

    Topics: Amino Acid Sequence; Amino Acid Substitution; Animals; Cysteine; Drug Delivery Systems; Enzyme Inhibitors; Glycine; HeLa Cells; Humans; Molecular Sequence Data; Monoacylglycerol Lipases; Mutagenesis, Site-Directed; Rats; Structure-Activity Relationship; Substrate Specificity; Thiazoles; Thiazolidines

2009
The multifunctional enzyme CYP71B15 (PHYTOALEXIN DEFICIENT3) converts cysteine-indole-3-acetonitrile to camalexin in the indole-3-acetonitrile metabolic network of Arabidopsis thaliana.
    The Plant cell, 2009, Volume: 21, Issue:6

    Topics: Arabidopsis; Arabidopsis Proteins; Cyanides; Cysteine; Cytochrome P-450 Enzyme System; Indoles; Mass Spectrometry; Metabolomics; NADP; Thiazoles

2009
A biomimetic synthesis of thiazolines using hexaphenyloxodiphosphonium trifluoromethanesulfonate.
    Angewandte Chemie (International ed. in English), 2003, Jan-03, Volume: 42, Issue:1

    Topics: Biomimetic Materials; Biomimetics; Cysteine; Dipeptides; Magnetic Resonance Spectroscopy; Mesylates; Molecular Conformation; Molecular Structure; Organophosphorus Compounds; Phosphoranes; Thiazoles

2003
Dura in the pathogenesis of syndromic craniosynostosis: fibroblast growth factor receptor 2 mutations in dural cells promote osteogenic proliferation and differentiation of osteoblasts.
    The Journal of craniofacial surgery, 2010, Volume: 21, Issue:2

    Topics: Acrocephalosyndactylia; Adenoviridae; Alkaline Phosphatase; Animals; Arginine; Biomarkers; Cell Differentiation; Cell Proliferation; Cells, Cultured; Coculture Techniques; Coloring Agents; Core Binding Factor Alpha 1 Subunit; Craniofacial Dysostosis; Craniosynostoses; Cysteine; Dura Mater; Genetic Vectors; Mice; Osteoblasts; Osteogenesis; Osteopontin; Phenylalanine; Point Mutation; Receptor, Fibroblast Growth Factor, Type 2; Syndrome; Tetrazolium Salts; Thiazoles

2010
Granular and lattice deposits in corneal dystrophy caused by R124C mutation of TGFBIp.
    Cornea, 2010, Volume: 29, Issue:11

    Topics: Adult; Amyloid; Antibody Specificity; Arginine; Benzothiazoles; Cornea; Corneal Dystrophies, Hereditary; Corneal Stroma; Cysteine; Extracellular Matrix Proteins; Fluorescent Antibody Technique; Fluorescent Dyes; Genotype; Heterozygote; Humans; Male; Mutation; Penetrance; Staining and Labeling; Thiazoles; Transforming Growth Factor beta

2010
The role of the C-terminus of human α-synuclein: intra-disulfide bonds between the C-terminus and other regions stabilize non-fibrillar monomeric isomers.
    FEBS letters, 2011, Feb-04, Volume: 585, Issue:3

    Topics: alpha-Synuclein; Benzothiazoles; Circular Dichroism; Cysteine; Cystine; Fluorescent Dyes; Humans; Isomerism; Kinetics; Mutagenesis, Site-Directed; Mutant Proteins; Oxidation-Reduction; Parkinson Disease; Protein Denaturation; Protein Folding; Protein Stability; Protein Structure, Secondary; Recombinant Proteins; Spectrometry, Fluorescence; Thiazoles

2011
Effects of 5-chloro-2-methyl-4-isothiazolin-3-one and other candidate biodiesel biocides on rat alveolar macrophages and NR8383 cells.
    Archives of toxicology, 2011, Volume: 85, Issue:11

    Topics: Alkynes; Animals; Biofuels; Cell Line; Cysteine; Cytokines; Disinfectants; Glutathione; Luminescence; Macrophages, Alveolar; Male; Rats; Rats, Sprague-Dawley; Respiratory Burst; Thiazoles; Tumor Necrosis Factor-alpha; Zymosan

2011
The cysteine reaction with diacetyl under wine-like conditions: proposed mechanisms for mixed origins of 2-methylthiazole, 2-methyl-3-thiazoline, 2-methylthiazolidine, and 2,4,5-trimethyloxazole.
    Journal of food science, 2011, Volume: 76, Issue:6

    Topics: Acetaldehyde; Cysteine; Databases, Factual; Diacetyl; Gas Chromatography-Mass Spectrometry; Hexanones; Methylation; Models, Chemical; Oxazoles; Thiazoles; Volatile Organic Compounds; Wine

2011
G-quadruplex DNAzyme-based Hg2+ and cysteine sensors utilizing Hg2+-mediated oligonucleotide switching.
    Biosensors & bioelectronics, 2011, Sep-15, Volume: 27, Issue:1

    Topics: Benzothiazoles; Biosensing Techniques; Colorimetry; Cysteine; DNA, Catalytic; Environmental Pollutants; G-Quadruplexes; Hemin; Limit of Detection; Mercury; Oligonucleotides; Sulfonic Acids; Thiazoles

2011
Saccharomyces cerevisiae THI4p is a suicide thiamine thiazole synthase.
    Nature, 2011, Oct-26, Volume: 478, Issue:7370

    Topics: Amino Acid Sequence; Biocatalysis; Carbon-Nitrogen Lyases; Conserved Sequence; Cysteine; Iron; Molecular Sequence Data; Recombinant Proteins; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Sulfides; Sulfur; Thiamine; Thiamine Pyrophosphate; Thiazoles

2011
Probing intein-catalyzed thioester formation by unnatural amino acid substitutions in the active site.
    Biochemistry, 2012, Jan-10, Volume: 51, Issue:1

    Topics: Amino Acid Substitution; Bacterial Proteins; Catalysis; Catalytic Domain; Cysteine; DnaB Helicases; Esters; Genetic Variation; Glycine; Homocysteine; Inteins; Molecular Sequence Data; Peptide Fragments; Protein Precursors; Protein Processing, Post-Translational; Protein Splicing; Signal Transduction; Sulfhydryl Compounds; Synechocystis; Thiazoles

2012
Cloning, expression, characterization and application of atcA, atcB and atcC from Pseudomonas sp. for the production of L-cysteine.
    Biotechnology letters, 2012, Volume: 34, Issue:6

    Topics: Amidohydrolases; Bacterial Proteins; Biotransformation; Cloning, Molecular; Cysteine; Escherichia coli; Gene Expression; Hydrolases; Metabolic Networks and Pathways; Pseudomonas; Racemases and Epimerases; Thiazoles

2012
Isolation and genetic improvement of Pseudomonas sp. strain HUT-78, capable of enzymatic production of L-cysteine from DL-2-amino-Δ2-thiazoline-4-carboxylic acid.
    The Journal of general and applied microbiology, 2011, Volume: 57, Issue:6

    Topics: Bacterial Proteins; Biotransformation; Cysteine; DNA, Bacterial; DNA, Ribosomal; Gene Expression; Metabolic Engineering; Metabolic Networks and Pathways; Mutation; Nitrogen; Pseudomonas; RNA, Ribosomal, 16S; Sequence Analysis, DNA; Soil Microbiology; Thiazoles; Ultraviolet Rays

2011
Hyaluronic acid L-cysteine conjugate exhibits controlled-release potential for mucoadhesive drug delivery.
    Die Pharmazie, 2012, Volume: 67, Issue:3

    Topics: Animals; Cell Line; Cell Membrane Permeability; Cell Survival; Chymotrypsin; Coloring Agents; Cysteine; Delayed-Action Preparations; Dogs; Drug Delivery Systems; Excipients; Hyaluronic Acid; Intestines; Mucous Membrane; Protease Inhibitors; Sulfhydryl Compounds; Tetrazolium Salts; Thiazoles; Tissue Adhesives; Trypsin Inhibitors

2012
Arabidopsis acetyl-amido synthetase GH3.5 involvement in camalexin biosynthesis through conjugation of indole-3-carboxylic acid and cysteine and upregulation of camalexin biosynthesis genes.
    Journal of integrative plant biology, 2012, Volume: 54, Issue:7

    Topics: Arabidopsis; Arabidopsis Proteins; Cysteine; Cytochrome P-450 Enzyme System; Indoles; Ligases; Plants, Genetically Modified; Thiazoles

2012
Ultraviolet A regulates the stemness of human adipose tissue-derived mesenchymal stem cells through downregulation of the HIF-1α via activation of PGE(2)-cAMP signaling.
    Journal of cellular biochemistry, 2012, Volume: 113, Issue:12

    Topics: Adipose Tissue; Basic Helix-Loop-Helix Transcription Factors; Cell Proliferation; Culture Media, Serum-Free; Cyclic AMP; Cysteine; Dinoprostone; Down-Regulation; Gene Expression Regulation; Homeodomain Proteins; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Mesenchymal Stem Cells; Mitogen-Activated Protein Kinase 1; Nanog Homeobox Protein; NF-kappa B; Octamer Transcription Factor-3; Radiation-Protective Agents; RNA, Messenger; Signal Transduction; SOXB1 Transcription Factors; Tetrazolium Salts; Thiazoles; Ultraviolet Rays

2012
Occurrence of 2-methylthiazolidine-4-carboxylic acid, a condensation product of cysteine and acetaldehyde, in human blood as a consequence of ethanol consumption.
    Analytical and bioanalytical chemistry, 2012, Volume: 404, Issue:6-7

    Topics: Acetaldehyde; Adult; Alcohol Drinking; Autopsy; Cysteine; Ethanol; Humans; Male; Molecular Structure; Thiazoles

2012
Inactivation of the glutamine/amino acid transporter ASCT2 by 1,2,3-dithiazoles: proteoliposomes as a tool to gain insights in the molecular mechanism of action and of antitumor activity.
    Toxicology and applied pharmacology, 2012, Nov-15, Volume: 265, Issue:1

    Topics: Amino Acid Transport System ASC; Amino Acid Transport Systems; Animals; Antineoplastic Agents; Binding Sites; Computer Simulation; Cysteine; Dose-Response Relationship, Drug; Glutamine; Kinetics; Minor Histocompatibility Antigens; Neoplasms; Proteolipids; Rats; Structure-Activity Relationship; Thiazoles

2012
Two-stage cultivation of Pseudomonas sp. F12 for the production of enzymes converting DL-2-amino-Δ²-thiazoline-4-carboxylic acid to L-cysteine.
    Applied biochemistry and biotechnology, 2012, Volume: 168, Issue:7

    Topics: Batch Cell Culture Techniques; Biotransformation; Carboxylic Acids; Culture Media; Cysteine; Cysteine Synthase; Glucose; Pseudomonas; Quaternary Ammonium Compounds; Thiazoles

2012
Solid phase versus solution phase synthesis of heterocyclic macrocycles.
    Molecules (Basel, Switzerland), 2013, Jan-16, Volume: 18, Issue:1

    Topics: Cyclization; Cysteine; Leucine; Oxidation-Reduction; Peptides, Cyclic; Serine; Solid-Phase Synthesis Techniques; Solutions; Thiazoles

2013
An enzymatic route to selenazolines.
    Chembiochem : a European journal of chemical biology, 2013, Mar-18, Volume: 14, Issue:5

    Topics: Amino Acid Sequence; Cysteine; Iodoacetamide; Multienzyme Complexes; Oxazoles; Peptides, Cyclic; Selenium; Selenocysteine; Serine; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Thiazoles; Threonine

2013
Progressive apraxic agraphia with micrographia presenting as corticobasal syndrome showing extensive Pittsburgh compound B uptake.
    Journal of neurology, 2013, Volume: 260, Issue:8

    Topics: Aged; Agraphia; Aniline Compounds; Apolipoproteins E; Apraxias; Basal Ganglia Diseases; Brain; Cerebral Cortex; Cysteine; Disease Progression; Executive Function; Female; Handwriting; Humans; Image Processing, Computer-Assisted; Intelligence Tests; Neurodegenerative Diseases; Neurologic Examination; Neuropsychological Tests; Organotechnetium Compounds; Positron-Emission Tomography; Radiopharmaceuticals; Reading; Thiazoles; Tomography, Emission-Computed, Single-Photon

2013
Stable label-free fluorescent sensing of biothiols based on ThT direct inducing conformation-specific G-quadruplex.
    Biosensors & bioelectronics, 2013, Nov-15, Volume: 49

    Topics: Benzothiazoles; Biosensing Techniques; Cysteine; Fluorescent Dyes; G-Quadruplexes; Glutathione; Humans; Limit of Detection; Spectrometry, Fluorescence; Thiazoles

2013
Clathrin-mediated endocytosis persists during unperturbed mitosis.
    Cell reports, 2013, Aug-29, Volume: 4, Issue:4

    Topics: Animals; Chlorocebus aethiops; Clathrin; Clathrin-Coated Vesicles; Cysteine; Endocytosis; HEK293 Cells; HeLa Cells; Hot Temperature; Humans; Mitosis; Nocodazole; Quinolines; Thiazoles; Transferrin

2013
Disulfide scrambling in superoxide dismutase 1 reduces its cytotoxic effect in cultured cells and promotes protein aggregation.
    PloS one, 2013, Volume: 8, Issue:10

    Topics: Acetamides; Apoenzymes; Benzothiazoles; Cell Line, Tumor; Cell Survival; Cysteine; Cytotoxins; Disulfides; Enzyme Stability; Humans; Protein Multimerization; Protein Structure, Quaternary; Sesquiterpenes; Solubility; Superoxide Dismutase; Superoxide Dismutase-1; Thiazoles

2013
Cysteine pseudoprolines for thiol protection and peptide macrocyclization enhancement in Fmoc-based solid-phase peptide synthesis.
    Organic letters, 2014, Mar-21, Volume: 16, Issue:6

    Topics: Cyclization; Cysteine; Dipeptides; Molecular Structure; Proline; Solid-Phase Synthesis Techniques; Sulfhydryl Compounds; Thiazoles

2014
Giardial triosephosphate isomerase as possible target of the cytotoxic effect of omeprazole in Giardia lamblia.
    Antimicrobial agents and chemotherapy, 2014, Volume: 58, Issue:12

    Topics: Albendazole; Antiprotozoal Agents; Axenic Culture; Cysteine; Dose-Response Relationship, Drug; Drug Resistance; Enzyme Inhibitors; Escherichia coli; Gene Expression; Giardia lamblia; Humans; Metronidazole; Mutation; Nitro Compounds; Omeprazole; Parasitic Sensitivity Tests; Protozoan Proteins; Recombinant Proteins; Spectrometry, Fluorescence; Thiazoles; Triose-Phosphate Isomerase; Trophozoites

2014
A short stereoselective synthesis of prepiscibactin using a SmI2-mediated Reformatsky reaction and Zn2+-induced asymmetric thiazolidine formation.
    Organic letters, 2014, Nov-07, Volume: 16, Issue:21

    Topics: Animals; Cysteine; Fish Diseases; Fishes; Iodides; Molecular Structure; Nitriles; Pasteurella Infections; Pfiesteria piscicida; Photobacterium; Samarium; Stereoisomerism; Thiazoles; Thiazolidines; Zinc

2014
Effect of organic-ligands on the toxicity profiles of CdS nanoparticles and functional properties.
    Colloids and surfaces. B, Biointerfaces, 2015, Feb-01, Volume: 126

    Topics: Animals; Cadmium Compounds; Cell Survival; Chlorocebus aethiops; Cysteine; Dose-Response Relationship, Drug; Ligands; Nanoparticles; Particle Size; Povidone; Structure-Activity Relationship; Sulfides; Surface Properties; Tetrazolium Salts; Thiazoles; Vero Cells

2015
Structural analysis of leader peptide binding enables leader-free cyanobactin processing.
    Nature chemical biology, 2015, Volume: 11, Issue:8

    Topics: Adenosine Triphosphate; Amino Acid Sequence; Bacterial Proteins; Binding Sites; Biocatalysis; Cyanobacteria; Cyclization; Cysteine; Gene Expression; Models, Molecular; Molecular Sequence Data; Peptides, Cyclic; Protein Engineering; Protein Processing, Post-Translational; Protein Sorting Signals; Protein Structure, Secondary; Protein Structure, Tertiary; Recombinant Proteins; Stereoisomerism; Substrate Specificity; Thiazoles

2015
C-S bond cleavage by a polyketide synthase domain.
    Proceedings of the National Academy of Sciences of the United States of America, 2015, Aug-18, Volume: 112, Issue:33

    Topics: Antibiotics, Antineoplastic; Carbon; Carbon-Sulfur Lyases; Computational Biology; Cysteine; Drug Design; Lactams; Macrolides; Multigene Family; Phylogeny; Polyketide Synthases; Polyketides; Protein Engineering; Protein Structure, Tertiary; Streptomyces; Substrate Specificity; Sulfhydryl Compounds; Sulfides; Thiazoles; Thiones

2015
In situ chemical behaviour of methylisothiazolinone (MI) and methylchloroisothiazolinone (MCI) in reconstructed human epidermis: a new approach to the cross-reactivity issue.
    Contact dermatitis, 2016, Volume: 74, Issue:3

    Topics: Cross Reactions; Cysteine; Epidermis; Histidine; Humans; Lysine; Magnetic Resonance Spectroscopy; Sulfhydryl Compounds; Thiazoles

2016
Formation scheme and antioxidant activity of a novel Maillard pigment, pyrrolothiazolate, formed from cysteine and glucose.
    Food & function, 2016, Jun-15, Volume: 7, Issue:6

    Topics: Antioxidants; Cyclization; Cysteine; Deoxyglucose; Glucose; Glycation End Products, Advanced; Isomerism; Pyrroles; Thiazoles

2016
A combination of quantitative marinating and Maillard reaction to enhance volatile flavor in Chinese marinated chicken.
    Journal of the science of food and agriculture, 2017, Volume: 97, Issue:3

    Topics: Animals; Beijing; Benzothiazoles; Chickens; Condiments; Cysteine; Flavoring Agents; Food Quality; Furans; Humans; Maillard Reaction; Meat; Molecular Structure; Salts; Sensation; Statistics as Topic; Taste; Thiamine; Thiazoles; Volatile Organic Compounds; Xylose

2017
A Simple and Effective Ratiometric Fluorescent Probe for the Selective Detection of Cysteine and Homocysteine in Aqueous Media.
    Molecules (Basel, Switzerland), 2016, Aug-05, Volume: 21, Issue:8

    Topics: Cysteine; Fluorescent Dyes; Glutathione; Homocysteine; Humans; Kinetics; Molecular Probe Techniques; Spectrometry, Fluorescence; Thiazoles

2016
Investigation of the relationship between the rodlet formation and Cys3-Cys4 loop of the HGFI hydrophobin.
    Colloids and surfaces. B, Biointerfaces, 2017, Feb-01, Volume: 150

    Topics: Benzothiazoles; Circular Dichroism; Congo Red; Cysteine; Fungal Proteins; Hydrophobic and Hydrophilic Interactions; Microscopy, Atomic Force; Photoelectron Spectroscopy; Polystyrenes; Protein Domains; Protein Structure, Secondary; Recombinant Proteins; Surface Properties; Thiazoles; Trichoderma; Water

2017
Drug susceptibility testing in microaerophilic parasites: Cysteine strongly affects the effectivities of metronidazole and auranofin, a novel and promising antimicrobial.
    International journal for parasitology. Drugs and drug resistance, 2017, Volume: 7, Issue:3

    Topics: Albendazole; Animals; Anti-Infective Agents; Antiparasitic Agents; Antiprotozoal Agents; Antirheumatic Agents; Auranofin; Culture Media; Cysteine; Entamoeba histolytica; Furazolidone; Giardia lamblia; Metronidazole; Nitro Compounds; Parasites; Parasitic Sensitivity Tests; Thiazoles; Trichomonas vaginalis

2017
Substrate selection of adenylation domains for nonribosomal peptide synthetase (NRPS) in bacillamide C biosynthesis by marine Bacillus atrophaeus C89.
    Journal of industrial microbiology & biotechnology, 2018, Volume: 45, Issue:5

    Topics: Bacillus; Cysteine; Molecular Docking Simulation; Peptide Synthases; Protein Domains; Substrate Specificity; Thiazoles; Tryptamines

2018
Benzisothiazolinone Derivatives as Potent Allosteric Monoacylglycerol Lipase Inhibitors That Functionally Mimic Sulfenylation of Regulatory Cysteines.
    Journal of medicinal chemistry, 2020, 02-13, Volume: 63, Issue:3

    Topics: Allosteric Regulation; Animals; Binding Sites; Cysteine; Enzyme Inhibitors; HeLa Cells; Humans; Mice; Molecular Docking Simulation; Molecular Structure; Monoacylglycerol Lipases; Mutagenesis, Site-Directed; Mutation; Oxidation-Reduction; Protein Binding; Rats; Structure-Activity Relationship; Thiazoles

2020
Modulating multi-functional ERK complexes by covalent targeting of a recruitment site in vivo.
    Nature communications, 2019, 11-19, Volume: 10, Issue:1

    Topics: Animals; Apoptosis; Binding Sites; Cell Line, Tumor; Cysteine; Dioxanes; HEK293 Cells; Humans; MAP Kinase Signaling System; Melanoma; Mice, Nude; Mitogen-Activated Protein Kinase 1; Molecular Dynamics Simulation; Protein Binding; Protein Kinase Inhibitors; Thiazoles; Xenograft Model Antitumor Assays

2019
De novo formation of citrate-based fluorophores on N-termini of peptides and proteins in cells and tissues.
    Chemical communications (Cambridge, England), 2020, Jan-04, Volume: 56, Issue:1

    Topics: Animals; Cell Line, Tumor; Citric Acid; Cysteine; Fluorescence; Fluorescent Dyes; HEK293 Cells; Humans; Mice; Microscopy, Confocal; Microscopy, Fluorescence; Molecular Probes; NIH 3T3 Cells; Peptides; Proof of Concept Study; Proteins; Pyridones; Serine; Thiazoles

2020
Structural Insights into Electrophile Irritant Sensing by the Human TRPA1 Channel.
    Neuron, 2020, 03-04, Volume: 105, Issue:5

    Topics: Acetamides; Cryoelectron Microscopy; Cysteine; HEK293 Cells; Humans; Irritants; Isothiocyanates; Models, Molecular; Nociceptors; Pain; Patch-Clamp Techniques; Phospholipids; Protein Domains; Protein Structure, Tertiary; Pruritus; Thiazoles; TRPA1 Cation Channel

2020
Total Synthesis of Micrococcin P1 through Scalable Thiazole Forming Reactions of Cysteine Derivatives and Nitriles.
    Organic letters, 2020, 03-20, Volume: 22, Issue:6

    Topics: Bacteriocins; Cysteine; Nitriles; Thiazoles

2020
Reinvestigation of 2-acetylthiazole formation pathways in the Maillard reaction.
    Food chemistry, 2021, May-30, Volume: 345

    Topics: Chromatography, High Pressure Liquid; Cysteine; Glucose; Glyoxal; Maillard Reaction; Odorants; Pyruvaldehyde; Tandem Mass Spectrometry; Thiazoles

2021
Near-infrared fluorogenic receptor for selective detection of cysteine in blood serum and living cells.
    Analytical and bioanalytical chemistry, 2021, Volume: 413, Issue:7

    Topics: Amino Acids; Cysteine; Fluorescent Dyes; HeLa Cells; Humans; Limit of Detection; Magnetic Resonance Spectroscopy; Solvents; Spectrometry, Mass, Electrospray Ionization; Spectroscopy, Near-Infrared; Tetrazolium Salts; Thiazoles

2021
Thiocysteine lyases as polyketide synthase domains installing hydropersulfide into natural products and a hydropersulfide methyltransferase.
    Nature communications, 2021, 09-28, Volume: 12, Issue:1

    Topics: Animals; Biological Products; Carbon-Sulfur Lyases; Cysteine; Cystine; Humans; Lactams; Macrolides; Methyltransferases; Models, Chemical; Molecular Structure; Peptide Synthases; Polyketide Synthases; src Homology Domains; Streptomyces; Substrate Specificity; Sulfides; Thiazoles; Thiones

2021
Formation Priority of Pyrazines and 2-Acetylthiazole Dependent on the Added Cysteine and Fragments of Deoxyosones during the Thermal Process of the Glycine-Ribose Amadori Compound.
    Journal of agricultural and food chemistry, 2022, Sep-21, Volume: 70, Issue:37

    Topics: Cysteamine; Cysteine; Glycine; Glyoxal; Magnesium Oxide; Maillard Reaction; Pyrazines; Pyruvaldehyde; Ribose; Thiazoles

2022