cysteine and sulfasalazine

cysteine has been researched along with sulfasalazine in 37 studies

Research

Studies (37)

TimeframeStudies, this research(%)All Research%
pre-19901 (2.70)18.7374
1990's6 (16.22)18.2507
2000's12 (32.43)29.6817
2010's14 (37.84)24.3611
2020's4 (10.81)2.80

Authors

AuthorsStudies
Salim, AS1
Bird, HA; Dixon, JS; Martin, MF; McKenna, F; Wright, V1
Brooks, P; Conaghan, PG1
Brooks, P; Conaghan, PG; Girgis, L1
Aono, H; Fujisawa, K; Hasunuma, T; Mita, S; Nakajima, T; Nishioka, K; Yamamoto, K1
Asano, G; Koda, M; Nakamura, H; Yoshino, S1
Murakami, T; Sugita, T; Takata, I; Ueno, M1
Hefferton, D; Rahman, P; Robb, D1
Asano, G; Nagashima, M; Yoshino, S1
Aono, H; Hirano, D; Ishigami, S; Nagashima, M; Sasano, M; Takai, M; Wauke, K; Yoshino, S1
Gomita, Y; Kawasaki, Y; Moriyama, M; Shibata, K1
Kawabata, D; Mimori, T1
Aoyama, M; Asai, K; Fukuoka, M; Kobayashi, M; Kusabe, T; Otsuka, T; Tanikawa, T; Waguri-Nagaya, Y1
Hara, M; Inoue, E; Iwatani, M; Kamatani, N; Nakajima, A; Nakamura, T; Tomatsu, T; Yamanaka, H1
Nakamura, K; Nakashima, T; Ochi, S; Oda, H; Suematsu, A; Tajiri, Y; Taka, J; Takayanagi, H; Tanaka, S1
Matsuda, T; Ohtsubo, H1
Yamanaka, H1
Mimori, T; Yukawa, N1
Abe, M; Kinoshita, M; Nakajima, M; Ohara, H; Ueda, N1
Kawai, S; Miyasaka, N; Takeuchi, T; Tanaka, Y; Yamamoto, K1
Koyama, Y; Ohta, T; Shiraishi, H; Uchino, A1
Amano, H; Kageyama, M; Kempe, K; Kusaoi, M; Matsudaira, R; Matsushita, M; Morimoto, S; Nawata, M; Ogasawara, M; Onuma, S; Sekiya, F; Tada, K; Takasaki, Y; Tamura, N; Toyama, S; Yamaji, K1
Ichikawa, N; Yamanaka, H1
Kageyama, M; Kempe, K; Kon, T; Kusaoi, M; Matsudaira, R; Matsushita, M; Ogasawara, M; Onuma, S; Sekiya, F; Sugimoto, K; Tada, K; Takasaki, Y; Tamura, N; Yamaji, K1
Tamura, N1
Tanaka, E; Yamanaka, H1
Itoh, K; Liu, T; Maruyama, A; Mimura, J; Ohyama, C; Okada, T; Sato, H; Ye, P1
Chen, L; Li, X; Liu, L; Liu, Y; Xue, Y; Yu, B1
Abe, C; Funahashi, K; Katayama, K; Kondo, M; Matsubara, T; Matsuno, H; Okada, M; Sagawa, A; Sakai, Y; Yamasaki, K1
Ito, S1
Albano, R; Lobner, D1
Cai, A; Chen, R; Chen, Z; Ganapathy, V; Kou, L; Sun, R; Xiao, S; Yao, Q; Zheng, H; Zheng, Y1
Hong, SE; Jang, SK; Jin, HO; Kim, HA; Kim, MR; Noh, WC; Park, IC; Seong, MK1
Capelletti, MM; Manceau, H; Peoc'h, K; Puy, H1
Nagase, S; Ohta, T; Seino, M; Sendo, K1
Adès, L; Alexe, G; Belloucif, Y; Benaksas, C; Berrou, J; Braun, T; Castelli, FA; Chat, L; Chauvel, C; Clappier, E; Dal Bello, R; de Thé, H; Dombret, H; Duchmann, M; Fenaille, F; Fenouille, N; Forget, A; Gardin, C; Huntly, BJ; Itzykson, R; Joudinaud, R; Laiguillon, MC; Ling, F; Lobry, C; Meduri, E; Pacchiardi, K; Pardieu, B; Pasanisi, J; Penneroux, J; Puissant, A; Raffoux, E; Sodaro, G; Stegmaier, K; Su, A; Vaganay, C; Vasseur, L; Wu, HC1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1

Reviews

11 review(s) available for cysteine and sulfasalazine

ArticleYear
Disease-modifying antirheumatic drugs, including methotrexate, gold, antimalarials, and D-penicillamine.
    Current opinion in rheumatology, 1995, Volume: 7, Issue:3

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Antimalarials; Antirheumatic Agents; Arthritis, Rheumatoid; Clinical Trials as Topic; Cysteine; Drug Therapy, Combination; Gold; Humans; Methotrexate; Penicillamine; Sulfasalazine

1995
Disease-modifying antirheumatic drugs, including methotrexate, sulfasalazine, gold, antimalarials, and penicillamine.
    Current opinion in rheumatology, 1994, Volume: 6, Issue:3

    Topics: Age Factors; Antimalarials; Arthritis, Rheumatoid; Clinical Trials as Topic; Cysteine; Digestive System; Gold; Humans; Liver; Methotrexate; Penicillamine; Sulfasalazine

1994
[Disease modifying anti-rheumatic drugs (DMARDs): an overview].
    Nihon rinsho. Japanese journal of clinical medicine, 2005, Volume: 63 Suppl 1

    Topics: Antirheumatic Agents; Arthritis, Rheumatoid; Benzopyrans; Cysteine; Evidence-Based Medicine; Gold Sodium Thiomalate; Humans; Isoxazoles; Leflunomide; Meta-Analysis as Topic; Methotrexate; Randomized Controlled Trials as Topic; Sulfasalazine; Sulfonamides

2005
[Effective combination therapy of TNF antagonists with DMARDs].
    Nihon rinsho. Japanese journal of clinical medicine, 2007, Volume: 65, Issue:7

    Topics: Adalimumab; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antirheumatic Agents; Arthritis, Rheumatoid; Azathioprine; Cysteine; Drug Therapy, Combination; Etanercept; Humans; Hydroxychloroquine; Immunoglobulin G; Infliximab; Isoxazoles; Leflunomide; Methotrexate; Receptors, Tumor Necrosis Factor; Sulfasalazine; Tumor Necrosis Factor-alpha

2007
[Antirheumatic agents for treatment of rheumatoid arthritis].
    Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine, 2008, Oct-10, Volume: 97, Issue:10

    Topics: Antirheumatic Agents; Arthritis, Rheumatoid; Cysteine; Gold Sodium Thiomalate; Humans; Isoxazoles; Leflunomide; Methotrexate; Pharmacogenetics; Randomized Controlled Trials as Topic; Remission Induction; Sulfasalazine; Time Factors

2008
[Effect of disease modifying anti-rheumatic drugs on radiographic progression in rheumatoid arthritis].
    Clinical calcium, 2009, Volume: 19, Issue:3

    Topics: Antirheumatic Agents; Arthritis, Rheumatoid; Cyclosporine; Cysteine; Disease Progression; Drug Therapy, Combination; Gold Sodium Thiomalate; Humans; Isoxazoles; Leflunomide; Methotrexate; Penicillamine; Radiography; Randomized Controlled Trials as Topic; Sulfasalazine; Tacrolimus

2009
[ Bone and cartilage destruction in RA and its intervention. Disease-modifying antirheumatic drugs].
    Clinical calcium, 2012, Volume: 22, Issue:2

    Topics: Antirheumatic Agents; Arthritis, Rheumatoid; Bone and Bones; Cartilage; Clinical Trials as Topic; Cysteine; Humans; Isoxazoles; Joints; Leflunomide; Methotrexate; Sulfasalazine; Tacrolimus

2012
[DMARDs (disease-modifying antirheumatic drugs)].
    Nihon rinsho. Japanese journal of clinical medicine, 2013, Volume: 71, Issue:7

    Topics: Antirheumatic Agents; Arthritis, Rheumatoid; Cysteine; Humans; Japan; Methotrexate; Sulfasalazine; Tacrolimus

2013
[DMARDs (Focusing on iguratimod)].
    Nihon rinsho. Japanese journal of clinical medicine, 2016, Volume: 74, Issue:6

    Topics: Antirheumatic Agents; Arthritis, Rheumatoid; Chromones; Cysteine; Drug Discovery; Drug Interactions; Drug Substitution; Drug Therapy, Combination; Drugs, Generic; Female; Humans; Male; Ribonucleosides; Sulfasalazine; Sulfonamides; Tacrolimus

2016
Ferroptosis in Liver Diseases: An Overview.
    International journal of molecular sciences, 2020, Jul-11, Volume: 21, Issue:14

    Topics: alpha-Tocopherol; Animals; Autophagy; Chemical and Drug Induced Liver Injury; Cyclohexylamines; Cysteine; Ferroptosis; Glutathione; Heme; Humans; Iron; Kelch-Like ECH-Associated Protein 1; Lipid Peroxidation; Lipoxygenase; Liver Diseases; Liver Neoplasms; Oxidative Stress; Phenylenediamines; Phospholipid Hydroperoxide Glutathione Peroxidase; Piperazines; Quinoxalines; Reactive Oxygen Species; Reperfusion Injury; Signal Transduction; Sorafenib; Spiro Compounds; Sulfasalazine; Tumor Suppressor Protein p53

2020
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Trials

4 trial(s) available for cysteine and sulfasalazine

ArticleYear
Role of sulphydryl-containing agents in the management of recurrent attacks of ulcerative colitis. A new approach.
    Pharmacology, 1992, Volume: 45, Issue:6

    Topics: Adult; Aged; Anti-Ulcer Agents; Colitis, Ulcerative; Cysteine; Double-Blind Method; Drug Administration Schedule; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Prednisolone; Prospective Studies; Recurrence; Sulfasalazine; Sulfhydryl Compounds; Vitamin U

1992
Efficacy profile of bucillamine in rheumatoid arthritis patients in a large observational cohort study, IORRA.
    Modern rheumatology, 2006, Volume: 16, Issue:6

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Cohort Studies; Cysteine; Drug Therapy, Combination; Female; Health Status; Humans; Joints; Male; Methotrexate; Middle Aged; Pain; Prednisolone; Prospective Studies; Remission Induction; Severity of Illness Index; Sulfasalazine

2006
A comparative study of the effects of bucillamine and salazosulfapyridine in the treatment of rheumatoid arthritis.
    Modern rheumatology, 2009, Volume: 19, Issue:4

    Topics: Antirheumatic Agents; Arthritis, Rheumatoid; C-Reactive Protein; Cysteine; Drug Therapy, Combination; Female; Hand Strength; Health Status; Humans; Joints; Male; Middle Aged; Pain; Prednisolone; Severity of Illness Index; Sulfasalazine; Time Factors; Treatment Outcome

2009
Efficacy and safety of additional use of tacrolimus in patients with early rheumatoid arthritis with inadequate response to DMARDs--a multicenter, double-blind, parallel-group trial.
    Modern rheumatology, 2011, Volume: 21, Issue:5

    Topics: Adult; Antirheumatic Agents; Arthritis, Rheumatoid; Cysteine; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Immunosuppressive Agents; Joints; Male; Methotrexate; Middle Aged; Severity of Illness Index; Sulfasalazine; Tacrolimus; Treatment Outcome

2011

Other Studies

22 other study(ies) available for cysteine and sulfasalazine

ArticleYear
Biochemical and clinical changes occurring during the treatment of rheumatoid arthritis with novel antirheumatoid drugs.
    International journal of clinical pharmacology research, 1985, Volume: 5, Issue:1

    Topics: Adult; Aged; Arthritis, Rheumatoid; Blood Viscosity; Captopril; Cysteine; Female; Humans; Male; Middle Aged; Penicillamine; Sulfasalazine; Sulfates; Zinc; Zinc Sulfate

1985
Direct suppression of human synovial cell proliferation in vitro by salazosulfapyridine and bucillamine.
    The Journal of rheumatology, 1996, Volume: 23, Issue:1

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Antirheumatic Agents; Base Sequence; Cell Division; Cells, Cultured; Cysteine; Drug Combinations; Humans; Interleukins; Models, Biological; Molecular Sequence Data; Sulfasalazine; Synovial Membrane

1996
[Effects of disease modifying antirheumatic drugs (DMARDs) and DEX on IL-1 beta and IL-6 production by IL-1 beta stimulated synovial culture cells].
    Nihon Ika Daigaku zasshi, 1996, Volume: 63, Issue:5

    Topics: Anti-Inflammatory Agents; Antirheumatic Agents; Cells, Cultured; Cysteine; Depression, Chemical; Dexamethasone; Gold Sodium Thiomalate; Humans; Interleukin-1; Interleukin-6; Methotrexate; Ribonucleosides; Sulfasalazine; Synovial Membrane; Tumor Necrosis Factor-alpha

1996
The novel anti-rheumatic drug TA-383 has a macrophage migration enhancing activity.
    Japanese journal of pharmacology, 1997, Volume: 74, Issue:2

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Reactive; Cell Movement; Chemotactic Factors; Collagen; Cysteine; Hypersensitivity, Delayed; Imidazoles; In Vitro Techniques; Macrophages, Alveolar; Mice; Mice, Inbred DBA; ortho-Aminobenzoates; Picryl Chloride; Rabbits; Sulfasalazine

1997
Increased MDR1 P-glycoprotein expression in methotrexate resistance: comment on the article by Yudoh et al.
    Arthritis and rheumatism, 2000, Volume: 43, Issue:7

    Topics: Antirheumatic Agents; Arthritis, Rheumatoid; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cysteine; Drug Interactions; Drug Resistance, Multiple; Humans; Methotrexate; Sulfasalazine; Th1 Cells

2000
Imbalance in production between vascular endothelial growth factor and endostatin in patients with rheumatoid arthritis.
    The Journal of rheumatology, 2000, Volume: 27, Issue:10

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Collagen; Cysteine; Drug Therapy, Combination; Endostatins; Endothelial Growth Factors; Enzyme-Linked Immunosorbent Assay; Fibroblast Growth Factor 2; Humans; Lymphokines; Middle Aged; Osteoarthritis; Peptide Fragments; Prednisolone; Sulfasalazine; Synovial Fluid; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors

2000
Effects of combinations of anti-rheumatic drugs on the production of vascular endothelial growth factor and basic fibroblast growth factor in cultured synoviocytes and patients with rheumatoid arthritis.
    Rheumatology (Oxford, England), 2000, Volume: 39, Issue:11

    Topics: Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Antirheumatic Agents; Arthritis, Rheumatoid; C-Reactive Protein; Cells, Cultured; Cysteine; Dexamethasone; Drug Synergism; Drug Therapy, Combination; Endothelial Growth Factors; Fibroblast Growth Factor 2; Gold Sodium Thiomalate; Humans; In Vitro Techniques; Lipopolysaccharides; Lymphokines; Methotrexate; Sulfasalazine; Synovial Membrane; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors

2000
[Examination of the escape phenomenon in disease modifying antirheumatic drugs].
    Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan, 2005, Volume: 125, Issue:3

    Topics: Aged; Antirheumatic Agents; Arthritis, Rheumatoid; Blood Sedimentation; C-Reactive Protein; Cysteine; Drug Therapy, Combination; Female; Humans; Male; Methotrexate; Middle Aged; Phenylacetates; Recurrence; Secondary Prevention; Sulfasalazine

2005
The inhibitory effect of disease-modifying anti-rheumatic drugs and steroids on gliostatin/platelet-derived endothelial cell growth factor production in human fibroblast-like synoviocytes.
    Rheumatology international, 2005, Volume: 25, Issue:8

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antirheumatic Agents; Arthritis, Rheumatoid; Cells; Cells, Cultured; Cysteine; Dexamethasone; Elbow; Female; Fibroblasts; Humans; Knee; Methotrexate; Middle Aged; Organogold Compounds; Orthopedic Procedures; Penicillamine; Phenylacetates; Sulfasalazine; Synovial Membrane; Thymidine Phosphorylase

2005
Scientific basis for the efficacy of combined use of antirheumatic drugs against bone destruction in rheumatoid arthritis.
    Modern rheumatology, 2007, Volume: 17, Issue:1

    Topics: Animals; Antirheumatic Agents; Arthritis, Rheumatoid; Bone Resorption; Cell Differentiation; Cells, Cultured; Coculture Techniques; Cysteine; Dose-Response Relationship, Drug; Drug Therapy, Combination; Methotrexate; Mice; Mice, Inbred C57BL; NFATC Transcription Factors; Osteoclasts; RANK Ligand; Sulfasalazine

2007
Etanercept in combination with conventional disease-modifying antirheumatic drugs (DMARDs) in the treatment of rheumatoid arthritis patients intolerant to methotrexate.
    Modern rheumatology, 2012, Volume: 22, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Antirheumatic Agents; Arthritis, Rheumatoid; Cysteine; Drug Substitution; Drug Therapy, Combination; Etanercept; Female; Glucocorticoids; Humans; Immunoglobulin G; Joints; Male; Methotrexate; Middle Aged; Pain Measurement; Receptors, Tumor Necrosis Factor; Recovery of Function; Retrospective Studies; Severity of Illness Index; Sulfasalazine; Treatment Failure

2012
Single-center, retrospective analysis of efficacy and safety of tacrolimus as a second-line DMARD in combination therapy and the risk factors contributing to adverse events in 115 patients with rheumatoid arthritis.
    Clinical rheumatology, 2012, Volume: 31, Issue:2

    Topics: Adult; Aged; Antirheumatic Agents; Arthritis, Rheumatoid; Cysteine; Disease Progression; Drug Therapy, Combination; Female; Humans; Male; Methotrexate; Middle Aged; Retrospective Studies; Risk Factors; Severity of Illness Index; Sulfasalazine; Tacrolimus; Treatment Outcome

2012
Recent trends in use of nonbiologic DMARDs and evaluation of their continuation rates in single and dual combination therapies in rheumatoid arthritis patients in Japan.
    Modern rheumatology, 2012, Volume: 22, Issue:6

    Topics: Adult; Antirheumatic Agents; Arthritis, Rheumatoid; Cysteine; Drug Therapy, Combination; Female; Humans; Japan; Male; Methotrexate; Practice Patterns, Physicians'; Severity of Illness Index; Sulfasalazine; Treatment Outcome

2012
[Rheumatoid arthritis: progress in diagnosis and treatment. Topics: IV. Treatment; 2. Antirheumatic agents, 1) non-biologic agents].
    Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine, 2012, Oct-10, Volume: 101, Issue:10

    Topics: Antirheumatic Agents; Arthritis, Rheumatoid; Cysteine; Female; Humans; Methotrexate; Sulfasalazine; Tacrolimus

2012
Nrf2- and ATF4-dependent upregulation of xCT modulates the sensitivity of T24 bladder carcinoma cells to proteasome inhibition.
    Molecular and cellular biology, 2014, Sep-15, Volume: 34, Issue:18

    Topics: Activating Transcription Factor 4; Amino Acid Transport System y+; Antineoplastic Agents; Boronic Acids; Bortezomib; Cell Line, Tumor; Cysteine; Gene Expression Regulation, Neoplastic; Gene Knockdown Techniques; Glutathione; Glycine; HEK293 Cells; HeLa Cells; Humans; Leupeptins; NF-E2-Related Factor 2; Oligopeptides; Proteasome Endopeptidase Complex; Pyrazines; RNA, Small Interfering; Sulfasalazine; Urinary Bladder Neoplasms

2014
Erastin sensitizes glioblastoma cells to temozolomide by restraining xCT and cystathionine-γ-lyase function.
    Oncology reports, 2015, Volume: 33, Issue:3

    Topics: Amino Acid Transport System y+; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Biological Transport; Brain Neoplasms; Cell Line, Tumor; Cell Survival; Cystathionine gamma-Lyase; Cysteine; Dacarbazine; Drug Resistance, Neoplasm; Enzyme Activation; Glioblastoma; Glutathione; Humans; NF-E2-Related Factor 2; Piperazines; Reactive Oxygen Species; RNA Interference; RNA, Small Interfering; Sulfasalazine; Temozolomide

2015
The usefulness of a new triple combination treatment utilizing methotrexate, salazosulfapyridine, and bucillamine in rheumatoid arthritis.
    Modern rheumatology, 2016, Volume: 26, Issue:1

    Topics: Adult; Aged; Antirheumatic Agents; Arthritis, Rheumatoid; Biological Products; Cysteine; Drug Therapy, Combination; Female; Humans; Japan; Male; Methotrexate; Middle Aged; Sulfasalazine; Treatment Outcome

2016
Transport of BMAA into Neurons and Astrocytes by System x
    Neurotoxicity research, 2018, Volume: 33, Issue:1

    Topics: Amino Acid Transport Systems; Amino Acids, Diamino; Animals; Aspartic Acid; Astrocytes; Carbon Isotopes; Cells, Cultured; Cerebral Cortex; Cyanobacteria Toxins; Cysteine; Embryo, Mammalian; Female; Glutamic Acid; Glutathione; Mice; Neurons; Neurotransmitter Uptake Inhibitors; Pregnancy; Sulfasalazine; Time Factors

2018
Ambidextrous Approach To Disrupt Redox Balance in Tumor Cells with Increased ROS Production and Decreased GSH Synthesis for Cancer Therapy.
    ACS applied materials & interfaces, 2019, Jul-31, Volume: 11, Issue:30

    Topics: Antineoplastic Agents; Cell Death; Cell Line, Tumor; Cell Proliferation; Cell Survival; Cysteine; Cystine; Glutathione; Humans; Nanoparticles; Neoplasms; Oxidation-Reduction; Oxidative Stress; Reactive Oxygen Species; Sulfasalazine; Zinc Oxide

2019
Hypoxia Suppresses Cysteine Deprivation-induced Cell Death
    Anticancer research, 2020, Volume: 40, Issue:3

    Topics: Activating Transcription Factor 4; Breast Neoplasms; Cell Death; Cell Hypoxia; Cell Line, Tumor; Cysteine; Female; Humans; Sulfasalazine; Transfection; Up-Regulation

2020
Impact of the glutathione synthesis pathway on sulfasalazine-treated endometrial cancer.
    Oncotarget, 2022, Volume: 13

    Topics: Amino Acid Transport System y+; Antioxidants; Antiporters; Carcinoma, Endometrioid; Cell Line, Tumor; Cisplatin; Cystathionine gamma-Lyase; Cysteine; Cystine; Female; Glutathione; Humans; Methionine; Reactive Oxygen Species; Sulfasalazine

2022
Cystine uptake inhibition potentiates front-line therapies in acute myeloid leukemia.
    Leukemia, 2022, Volume: 36, Issue:6

    Topics: Cell Line, Tumor; Cysteine; Cystine; Daunorubicin; Humans; Leukemia, Myeloid, Acute; Nuclear Proteins; Sulfasalazine

2022