cysteine and sirolimus

cysteine has been researched along with sirolimus in 14 studies

Research

Studies (14)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (7.14)18.2507
2000's2 (14.29)29.6817
2010's6 (42.86)24.3611
2020's5 (35.71)2.80

Authors

AuthorsStudies
Kudla, J; Liang, S; Luan, S; Xu, Q1
Ginalski, K; Grishin, NV; Zhang, H1
Dames, SA; Grzesiek, S; Hall, MN; Mulet, JM; Rathgeb-Szabo, K1
Suzuki, N1
Aiba, K; Isobe, K; Ito, S; Nishio, N; Oshino, R; Tanaka, Y; Thanasegaran, S1
Coleman, RA; Cooper, DE; Ellis, JM; Grevengoed, TJ; Jia, W; Pascual, F; Patterson, C; Paul, DS; Schisler, JC; Willis, MS1
Cheng, L; Li, S; Sun, Y; Yang, G; Zhao, Z; Zhu, X1
Heidler, J; Scheving, R; Tegeder, I; Valek, L; Wittig, I1
Enokidani, Y; Fujiwara, M; Hamasaki, M; Ishii, M; Kawabata, T; Kumanogoh, A; Nakamura, S; Nishikawa, K; Saita, S; Tabata, K; Takamatsu, H; Yamamuro, T; Yoshida, G; Yoshimori, T1
Ergen, E; Kerimoglu, B; Lamb, C; McPherson, RD; Ooi, A; Stone, EM1
Abaffy, P; Barinka, C; Benda, A; Blecha, J; Bohuslavova, R; Carmeliet, P; Dewerchin, M; Goveia, J; Kalucka, J; Khan, S; Machan, R; Magalhaes-Novais, S; Mikesova, J; Milosevic, M; Mracek, T; Naraine, R; Neuzil, J; Novotna, E; Pecinova, A; Prochazka, J; Rohlena, J; Rohlenova, K; Sindelka, R; Stemberkova Hubackova, S; Vlcak, E1
Agbonifo-Chijiokwu, E; Edesiri, TP; Faith, FY; Kingsley, NE; Mega, OO; Oghenetega, BO; Rume, RA; Simon, OI; Victor, E1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Arora, S; Chaturvedi, A; Heuser, M; Joshi, G; Kumar, R; Patil, S1

Reviews

2 review(s) available for cysteine and sirolimus

ArticleYear
Mass spectrometry-based quantitative analysis and biomarker discovery.
    Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan, 2011, Volume: 131, Issue:9

    Topics: 12-Hydroxy-5,8,10,14-eicosatetraenoic Acid; Animals; Arachidonic Acid; Biomarkers; Cysteine; Drug Monitoring; Early Diagnosis; Humans; Immunosuppressive Agents; Leukotrienes; Mass Spectrometry; Metabolomics; Sirolimus; Thromboxanes

2011
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Other Studies

12 other study(ies) available for cysteine and sirolimus

ArticleYear
Molecular characterization of a plant FKBP12 that does not mediate action of FK506 and rapamycin.
    The Plant journal : for cell and molecular biology, 1998, Volume: 15, Issue:4

    Topics: Amino Acid Sequence; Calcineurin; Cloning, Molecular; Cysteine; Disulfides; Dithiothreitol; Fabaceae; Genes, Plant; Genetic Complementation Test; Immunophilins; Immunosuppressive Agents; Molecular Sequence Data; Mutation; Plants, Medicinal; Protein Binding; Protein Structure, Tertiary; Sequence Analysis, DNA; Sequence Homology, Amino Acid; Sirolimus; Sulfhydryl Reagents; Tacrolimus; Tacrolimus Binding Proteins

1998
Raptor protein contains a caspase-like domain.
    Trends in biochemical sciences, 2004, Volume: 29, Issue:10

    Topics: Adaptor Proteins, Signal Transducing; Amino Acid Motifs; Amino Acid Sequence; Animals; Caspases; Catalysis; Cysteine; Histidine; Humans; Molecular Sequence Data; Peptide Hydrolases; Proteins; Regulatory-Associated Protein of mTOR; Sequence Homology, Amino Acid; Signal Transduction; Sirolimus

2004
The solution structure of the FATC domain of the protein kinase target of rapamycin suggests a role for redox-dependent structural and cellular stability.
    The Journal of biological chemistry, 2005, May-27, Volume: 280, Issue:21

    Topics: Amino Acid Sequence; Animals; Binding Sites; Conserved Sequence; Cysteine; Disulfides; Drug Stability; Magnetic Resonance Spectroscopy; Models, Molecular; Molecular Sequence Data; Mutagenesis; Oxidation-Reduction; Peptide Fragments; Phosphatidylinositol 3-Kinases; Phosphotransferases (Alcohol Group Acceptor); Protein Structure, Secondary; Recombinant Fusion Proteins; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Sequence Alignment; Serine; Sirolimus; Structure-Activity Relationship; Temperature

2005
GADD34 inhibits activation-induced apoptosis of macrophages through enhancement of autophagy.
    Scientific reports, 2015, Feb-09, Volume: 5

    Topics: Animals; Apoptosis; Autophagy; Caspase 3; Cell Line; Cysteine; Gene Expression; Gene Knockdown Techniques; Humans; Lipopolysaccharides; Macrophage Activation; Macrophages; Mice; Mice, Knockout; Protein Phosphatase 1; Signal Transduction; Sirolimus; TOR Serine-Threonine Kinases; Tyrosine

2015
Cardiac energy dependence on glucose increases metabolites related to glutathione and activates metabolic genes controlled by mechanistic target of rapamycin.
    Journal of the American Heart Association, 2015, Feb-24, Volume: 4, Issue:2

    Topics: Animals; Carbohydrate Metabolism; Coenzyme A Ligases; Cysteine; Fatty Acids; Glucose; Glutathione; Lipid Metabolism; Mice; Mice, Knockout; Myocardium; Oxidation-Reduction; Sirolimus; TOR Serine-Threonine Kinases

2015
Combination of rapamycin and garlic-derived S-allylmercaptocysteine induces colon cancer cell apoptosis and suppresses tumor growth in xenograft nude mice through autophagy/p62/Nrf2 pathway.
    Oncology reports, 2017, Volume: 38, Issue:3

    Topics: Animals; Antineoplastic Agents; Antioxidants; Apoptosis; Autophagy; Cell Line, Tumor; Cell Proliferation; Colonic Neoplasms; Cysteine; Down-Regulation; Garlic; HCT116 Cells; Humans; Mice; Mice, Inbred BALB C; Mice, Nude; NF-E2-Related Factor 2; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-bcl-2; RNA-Binding Proteins; Signal Transduction; Sirolimus; Transplantation, Heterologous; Xenograft Model Antitumor Assays

2017
Nitric oxide contributes to protein homeostasis by S-nitrosylations of the chaperone HSPA8 and the ubiquitin ligase UBE2D.
    Redox biology, 2019, Volume: 20

    Topics: Autophagy; Cell Cycle; Cell Line; Cell Proliferation; Cellular Senescence; Cysteine; HSC70 Heat-Shock Proteins; Humans; Lysosomes; Molecular Chaperones; Nitric Oxide; Oxidation-Reduction; Proteome; Proteostasis; Sirolimus; Ubiquitin-Conjugating Enzymes; Ubiquitination

2019
Degradation of the NOTCH intracellular domain by elevated autophagy in osteoblasts promotes osteoblast differentiation and alleviates osteoporosis.
    Autophagy, 2022, Volume: 18, Issue:10

    Topics: Alkaline Phosphatase; Animals; Autophagy; Beclin-1; Cell Differentiation; Core Binding Factor Alpha 1 Subunit; Cysteine; Mice; Microtubule-Associated Proteins; Osteoblasts; Osteocalcin; Osteogenesis; Osteoporosis; Osteoprotegerin; Phosphates; Receptors, Notch; Selective Estrogen Receptor Modulators; Sirolimus; TOR Serine-Threonine Kinases

2022
Cyst(e)inase-Rapamycin Combination Induces Ferroptosis in Both In Vitro and In Vivo Models of Hereditary Leiomyomatosis and Renal Cell Cancer.
    Molecular cancer therapeutics, 2022, 03-01, Volume: 21, Issue:3

    Topics: Animals; Carcinoma, Renal Cell; Cysteine; Cysts; Female; Ferroptosis; Humans; Kidney Neoplasms; Leiomyomatosis; Male; Mice; Neoplastic Syndromes, Hereditary; Sirolimus; Skin Neoplasms; Uterine Neoplasms

2022
Mitochondrial respiration supports autophagy to provide stress resistance during quiescence.
    Autophagy, 2022, Volume: 18, Issue:10

    Topics: Adenosine Triphosphate; AMP-Activated Protein Kinases; Animals; Autophagy; Cysteine; Dextrans; DNA, Mitochondrial; Endothelial Cells; Fibroblasts; Formaldehyde; Humans; Inflammatory Bowel Diseases; Isothiocyanates; Lipopolysaccharides; Mechanistic Target of Rapamycin Complex 1; Mice; Microtubule-Associated Proteins; Mitochondria; Phosphatidylethanolamines; Reactive Oxygen Species; Respiration; Sirolimus

2022
d-ribose- l-cysteine abrogates testicular maladaptive responses induced by polychlorinated bisphenol intoxication in rats via activation of the mTOR signaling pathway mediating inhibition of apoptosis, inflammation, and oxidonitrergic flux.
    Journal of biochemical and molecular toxicology, 2022, Volume: 36, Issue:10

    Topics: Animals; Antioxidants; Apoptosis; Autophagy-Related Proteins; Caspase 3; Catalase; Cysteine; Environmental Pollutants; Follicle Stimulating Hormone; Glutathione Peroxidase; Inflammation; Luteinizing Hormone; Male; Malondialdehyde; Mammals; Oxidative Stress; Polychlorinated Biphenyls; Rats; Ribose; Semen; Signal Transduction; Sirolimus; Superoxide Dismutase; Testis; Testosterone; Thiazolidines; TOR Serine-Threonine Kinases; Tumor Necrosis Factor-alpha; Tumor Suppressor Protein p53

2022
A Perspective on Medicinal Chemistry Approaches for Targeting Pyruvate Kinase M2.
    Journal of medicinal chemistry, 2022, 01-27, Volume: 65, Issue:2

    Topics: Allosteric Regulation; Allosteric Site; Carrier Proteins; Chemistry, Pharmaceutical; Glycolysis; Humans; Membrane Proteins; Protein Kinase Inhibitors; Thyroid Hormone-Binding Proteins; Thyroid Hormones

2022