cysteine and s-farnesylcysteine

cysteine has been researched along with s-farnesylcysteine in 33 studies

Research

Studies (33)

TimeframeStudies, this research(%)All Research%
pre-19902 (6.06)18.7374
1990's22 (66.67)18.2507
2000's4 (12.12)29.6817
2010's5 (15.15)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Buss, JE; Cox, AD; Der, CJ; Hisaka, MM1
Heilmeyer, LM; Hoffmann-Posorske, E; Metzger, J; Meyer, HE; Serwe, M; Weber, C1
Black, SD1
Ashby, MN; King, DS; Rine, J1
Fisher, P; Havel, CM; Watson, JA1
Johnson, M; Kwee, C; Lane, P; Stock, J; Volker, C1
Backer, JM; McCleary, WR; Miller, RA; Poenie, M; Rao, A; Stock, JB; Volker, C1
Bruenger, E; Epstein, WW; Leining, LM; Lever, D; Rilling, HC1
Clarke, S; Deschenes, RJ; Stimmel, JB; Stock, J; Volker, C1
Clarke, S; Stephenson, RC1
Farnsworth, CC; Gelb, MH; Glomset, JA; Wolda, SL1
Anderegg, RJ; Betz, R; Carr, SA; Crabb, JW; Duntze, W1
Casey, PJ; Fine, RL; Sachs, CW; Zhang, L1
Anant, JS; Fung, BK; Lin, WC; Ong, OC; Yamane, HK1
Lim, YH; Ma, YT; McGrail, SH; Rando, RR; Shi, YQ; Ware, JA1
Badwey, JA; Ding, J; Gilbert, BA; Lu, DJ; Ma, YT; Maddox, JF; Pérez-Sala, D; Rando, RR1
Bruenger, E; Buss, JE; Epstein, WW; Leining, LM; Rilling, HC1
Hamilton, AD; Qian, Y; Sebti, SM; Vogt, A1
Aviram, I; Halpern, M; Kloog, Y; Marciano, D; Tisch, D1
Burrell, SK; Dalton, MB; Kilic, F; Mayer, JP; Patterson, SD; Sinensky, M1
Casey, PJ; Tschantz, WR; Zhang, L1
Aharonson, Z; Gana-Weisz, M; Haklai, R; Kloog, Y; Marciano, D; Varsano, T1
Cañada, FJ; Gilbert, BA; Pérez-Sala, D; Rando, RR1
Ha, KW; Han, BS; Han, ES; Han, JW; Hong, S; Hong, SM; Lee, HW; Noh, SH; Oh, HY1
Charlton, CG; Lamango, NS1
Casey, PJ; Coates, RM; Digits, JA; Pyun, HJ; Tschantz, WR1
Crowell, DN; Deem, AK; Denton, R; Huizinga, DH; Sen, SE; Trobaugh, C1
Donelson, JL; Gibbs, RA; Henriksen, BS; Hodges-Loaiza, HB; Hrycyna, CA1
Crowell, DN; Denton, R; Huizinga, DH; Koehler, KG; Sen, SE; Tomasello, A; Wood, L1
Gibbs, RA; Hahne, K; Hrycyna, CA; Majmudar, JD1
Haklai, R; Kloog, Y; Makovski, V1
Geffard, M; Kubera, M; Leunis, JC; Maes, M; Mihaylova, I1
Geffard, M; Kubera, M; Leunis, JC; Maes, M; Mihaylova, I; Twisk, FN1

Other Studies

33 other study(ies) available for cysteine and s-farnesylcysteine

ArticleYear
Specific isoprenoid modification is required for function of normal, but not oncogenic, Ras protein.
    Molecular and cellular biology, 1992, Volume: 12, Issue:6

    Topics: 3T3 Cells; Amino Acid Sequence; Animals; Cell Division; Cell Membrane; Cell Transformation, Neoplastic; Cysteine; Diterpenes; Farnesol; GTP-Binding Proteins; Mice; Molecular Sequence Data; Mutagenesis, Site-Directed; Protein Processing, Post-Translational; Proto-Oncogene Proteins p21(ras); Proto-Oncogene Proteins pp60(c-src); rap GTP-Binding Proteins; Structure-Activity Relationship

1992
Farnesylcysteine, a constituent of the alpha and beta subunits of rabbit skeletal muscle phosphorylase kinase: localization by conversion to S-ethylcysteine and by tandem mass spectrometry.
    Proceedings of the National Academy of Sciences of the United States of America, 1992, Oct-15, Volume: 89, Issue:20

    Topics: Amino Acid Sequence; Animals; Cysteine; Mass Spectrometry; Molecular Sequence Data; Muscles; Peptide Fragments; Phosphorylase Kinase; Protein Prenylation; Rabbits

1992
Development of hydrophobicity parameters for prenylated proteins.
    Biochemical and biophysical research communications, 1992, Aug-14, Volume: 186, Issue:3

    Topics: Amino Acid Sequence; Cysteine; Diterpenes; Molecular Conformation; Molecular Sequence Data; Molecular Structure; Protein Conformation; Proteins; Thermodynamics

1992
Endoproteolytic processing of a farnesylated peptide in vitro.
    Proceedings of the National Academy of Sciences of the United States of America, 1992, May-15, Volume: 89, Issue:10

    Topics: Amino Acid Sequence; Cell Membrane; Cysteine; Cytosol; Endopeptidases; Kinetics; Mating Factor; Methyltransferases; Molecular Sequence Data; Oligopeptides; Peptides; Pheromones; Protein Processing, Post-Translational; Saccharomyces cerevisiae; Substrate Specificity

1992
Isopentenoid synthesis in embryonic Drosophila cells: prenylated protein profile and prenyl group usage.
    Archives of biochemistry and biophysics, 1992, Volume: 295, Issue:2

    Topics: Animals; Cells, Cultured; Chromatography, High Pressure Liquid; Cysteine; Diterpenes; Drosophila; Electrophoresis, Gel, Two-Dimensional; Electrophoresis, Polyacrylamide Gel; Gas Chromatography-Mass Spectrometry; Hydrolysis; Mevalonic Acid; Proteins

1992
A single activity carboxyl methylates both farnesyl and geranylgeranyl cysteine residues.
    FEBS letters, 1991, Dec-16, Volume: 295, Issue:1-3

    Topics: Animals; Brain; Cysteine; Diterpenes; Humans; Kinetics; Liver; Methylation; Protein Methyltransferases; Protein Processing, Post-Translational; Proto-Oncogene Proteins p21(ras); Rats; Recombinant Proteins; Saccharomyces cerevisiae; Subcellular Fractions; Substrate Specificity

1991
Effects of farnesylcysteine analogs on protein carboxyl methylation and signal transduction.
    The Journal of biological chemistry, 1991, Nov-15, Volume: 266, Issue:32

    Topics: Alkyl and Aryl Transferases; Animals; Cell Line; Cell Transformation, Neoplastic; Chemotaxis; Cysteine; GTP-Binding Proteins; Macromolecular Substances; Macrophages; Male; Mice; Mice, Inbred BALB C; Models, Biological; Organ Specificity; Proto-Oncogene Proteins p21(ras); Rats; Signal Transduction; Structure-Activity Relationship; Substrate Specificity; Transferases

1991
Quantitation of prenylcysteines by a selective cleavage reaction.
    Proceedings of the National Academy of Sciences of the United States of America, 1991, Nov-01, Volume: 88, Issue:21

    Topics: 3T3 Cells; Animals; CHO Cells; Chromatography, High Pressure Liquid; Cricetinae; Cysteine; Diterpenes; HeLa Cells; Humans; Mevalonic Acid; Mice; Naphthols; Protein Processing, Post-Translational

1991
Evidence for an S-farnesylcysteine methyl ester at the carboxyl terminus of the Saccharomyces cerevisiae RAS2 protein.
    Biochemistry, 1990, Oct-16, Volume: 29, Issue:41

    Topics: Amino Acid Sequence; Animals; Chromatography, High Pressure Liquid; Cysteine; Fungal Proteins; Humans; Molecular Sequence Data; Plasmids; Protein Processing, Post-Translational; ras Proteins; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Sequence Homology, Nucleic Acid

1990
Identification of a C-terminal protein carboxyl methyltransferase in rat liver membranes utilizing a synthetic farnesyl cysteine-containing peptide substrate.
    The Journal of biological chemistry, 1990, Sep-25, Volume: 265, Issue:27

    Topics: Amino Acid Sequence; Animals; Cell Membrane; Cysteine; Female; Hydrogen-Ion Concentration; Kinetics; Liver; Methylation; Molecular Sequence Data; Oligopeptides; Protein Methyltransferases; Protein O-Methyltransferase; Rats; Rats, Inbred Strains; Rod Cell Outer Segment; Substrate Specificity

1990
Human lamin B contains a farnesylated cysteine residue.
    The Journal of biological chemistry, 1989, Dec-05, Volume: 264, Issue:34

    Topics: Amino Acid Sequence; Cell Nucleus; Cyanogen Bromide; Cysteine; Gas Chromatography-Mass Spectrometry; HeLa Cells; Humans; Indicators and Reagents; Lamin Type B; Lamins; Mevalonic Acid; Molecular Sequence Data; Nuclear Proteins; Peptide Hydrolases; Sequence Homology, Nucleic Acid; Sulfur Radioisotopes; Tritium

1989
Structure of Saccharomyces cerevisiae mating hormone a-factor. Identification of S-farnesyl cysteine as a structural component.
    The Journal of biological chemistry, 1988, Dec-05, Volume: 263, Issue:34

    Topics: Amino Acid Sequence; Chromatography, Gas; Cysteine; Magnetic Resonance Spectroscopy; Mass Spectrometry; Mating Factor; Peptides; Pheromones; Saccharomyces cerevisiae

1988
Interaction of prenylcysteine methyl esters with the multidrug resistance transporter.
    The Journal of biological chemistry, 1994, Jun-10, Volume: 269, Issue:23

    Topics: Adenosine Triphosphatases; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Carrier Proteins; Cysteine; Diterpenes; Drug Resistance; Esters; Humans; Ligands; Membrane Glycoproteins; Moths; Protein Prenylation; Recombinant Proteins; Substrate Specificity; Terpenes; Tumor Cells, Cultured

1994
Isoprenylation of gamma subunits and G-protein effectors.
    Methods in enzymology, 1994, Volume: 237

    Topics: Alkyl and Aryl Transferases; Amino Acid Sequence; Animals; Cysteine; Diterpenes; Electrophoresis, Polyacrylamide Gel; Farnesyltranstransferase; GTP-Binding Proteins; Macromolecular Substances; Mevalonic Acid; Molecular Sequence Data; Molecular Weight; Protein Prenylation; Radioisotope Dilution Technique; Rats; Retina; Rod Cell Outer Segment; Transferases; Tritium

1994
Mechanistic studies on human platelet isoprenylated protein methyltransferase: farnesylcysteine analogs block platelet aggregation without inhibiting the methyltransferase.
    Biochemistry, 1994, May-10, Volume: 33, Issue:18

    Topics: Animals; Blood Platelets; Cattle; Cell Membrane; Cysteine; Humans; In Vitro Techniques; Kinetics; Methyltransferases; Platelet Aggregation Inhibitors; Protein Prenylation

1994
Farnesyl-L-cysteine analogs can inhibit or initiate superoxide release by human neutrophils.
    The Journal of biological chemistry, 1994, Jun-17, Volume: 269, Issue:24

    Topics: Chromatography, High Pressure Liquid; Cysteine; Humans; In Vitro Techniques; Indicators and Reagents; Kinetics; Magnetic Resonance Spectroscopy; Molecular Structure; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phosphoproteins; Structure-Activity Relationship; Superoxide Dismutase; Superoxides; Tetradecanoylphorbol Acetate

1994
Differential prenylation of proteins as a function of mevalonate concentration in CHO cells.
    Archives of biochemistry and biophysics, 1993, Volume: 301, Issue:2

    Topics: Animals; CHO Cells; Cholesterol; Cricetinae; Cysteine; Diterpenes; Dose-Response Relationship, Drug; Lipid Metabolism; Lipoproteins; Mevalonic Acid; Oncogene Protein p21(ras); Protein Prenylation

1993
Design and synthesis of non-peptide Ras CAAX mimetics as potent farnesyltransferase inhibitors.
    Journal of medicinal chemistry, 1996, Jan-05, Volume: 39, Issue:1

    Topics: Alkyl and Aryl Transferases; Amino Acid Sequence; Biphenyl Compounds; Cysteine; Drug Design; Enzyme Inhibitors; Magnetic Resonance Spectroscopy; Mass Spectrometry; Molecular Sequence Data; Oncogene Protein p21(ras); Protein Prenylation; Structure-Activity Relationship; Transferases; Tumor Cells, Cultured

1996
Activation of signaling pathways in HL60 cells and human neutrophils by farnesylthiosalicylate.
    European journal of biochemistry, 1996, Dec-15, Volume: 242, Issue:3

    Topics: Calcium; Cell Compartmentation; Cysteine; Enzyme Activation; Enzyme Inhibitors; Farnesol; GTP-Binding Proteins; HL-60 Cells; Humans; Inositol 1,4,5-Trisphosphate; NADPH Oxidases; Neutrophils; Pertussis Toxin; Phospholipases; Protein Kinase C; Respiratory Burst; Salicylates; Signal Transduction; Staurosporine; Superoxides; Virulence Factors, Bordetella

1996
In vitro assay and characterization of the farnesylation-dependent prelamin A endoprotease.
    The Journal of biological chemistry, 1997, Feb-21, Volume: 272, Issue:8

    Topics: Amino Acid Sequence; Binding Sites; Cysteine; Endopeptidases; HeLa Cells; Humans; Lamin Type A; Molecular Sequence Data; Nuclear Proteins; Protein Precursors

1997
Isolation and characterization of a prenylcysteine lyase from bovine brain.
    The Journal of biological chemistry, 1997, Sep-12, Volume: 272, Issue:37

    Topics: Animals; Brain; Carbon-Sulfur Lyases; Cattle; Cysteine; Dipeptides; Farnesol; Kinetics; Lyases; Models, Chemical; Nerve Tissue Proteins; Protein Prenylation; Substrate Specificity

1997
Stringent structural requirements for anti-Ras activity of S-prenyl analogues.
    Biochimica et biophysica acta, 1998, Feb-27, Volume: 1406, Issue:1

    Topics: Animals; Cell Division; Cell Line; Cysteine; Dose-Response Relationship, Drug; Enzyme Inhibitors; Farnesol; ras Proteins; Rats; Salicylates; Transfection

1998
Analogs of farnesylcysteine induce apoptosis in HL-60 cells.
    FEBS letters, 1998, Apr-24, Volume: 426, Issue:3

    Topics: Acetylcysteine; Apoptosis; Cell Cycle; Cysteine; DNA Methylation; Farnesol; Growth Inhibitors; HL-60 Cells; Humans; Proteins; ras Proteins; Subcellular Fractions

1998
Farnesylcysteine methyltransferase activity and Ras protein expression in human stomach tumor tissue.
    Archives of pharmacal research, 1998, Volume: 21, Issue:4

    Topics: Adenocarcinoma; Adult; Aged; Cysteine; Enzyme Activation; Gene Expression; Humans; Immunohistochemistry; Middle Aged; Protein Methyltransferases; ras Proteins; S-Adenosylhomocysteine; Stomach; Stomach Neoplasms

1998
Farnesyl-L-cysteine analogs block SAM-induced Parkinson's disease-like symptoms in rats.
    Pharmacology, biochemistry, and behavior, 2000, Volume: 66, Issue:4

    Topics: Amphetamine; Animals; Central Nervous System Stimulants; Chromatography, Gel; Cysteine; Freeze Drying; Male; Methylation; Motor Activity; Nerve Tissue Proteins; Oxidopamine; Parkinson Disease, Secondary; Rats; Rats, Sprague-Dawley; S-Adenosylmethionine; Stereotyped Behavior; Sympathectomy, Chemical; Tremor

2000
Lysosomal prenylcysteine lyase is a FAD-dependent thioether oxidase.
    The Journal of biological chemistry, 2001, Jan-26, Volume: 276, Issue:4

    Topics: Carbon-Sulfur Lyases; Cysteine; Farnesol; Flavin-Adenine Dinucleotide; Hydrogen Peroxide; Lysosomes; Models, Chemical; Sulfides

2001
Arabidopsis thaliana plants possess a specific farnesylcysteine lyase that is involved in detoxification and recycling of farnesylcysteine.
    The Plant journal : for cell and molecular biology, 2007, Volume: 50, Issue:5

    Topics: Amino Acid Sequence; Arabidopsis; Arabidopsis Proteins; Carbon-Sulfur Lyases; Cysteine; DNA, Plant; Farnesol; Inactivation, Metabolic; Kinetics; Molecular Sequence Data; Protein Methyltransferases; Sequence Alignment; Sequence Homology, Amino Acid

2007
Solid-phase synthesis of prenylcysteine analogs.
    The Journal of organic chemistry, 2009, Apr-17, Volume: 74, Issue:8

    Topics: Amino Acid Sequence; Chromatography, High Pressure Liquid; Cysteine; Humans; Molecular Structure; Protein Methyltransferases; Solid Phase Extraction; Trityl Compounds

2009
Farnesylcysteine lyase is involved in negative regulation of abscisic acid signaling in Arabidopsis.
    Molecular plant, 2010, Volume: 3, Issue:1

    Topics: Abscisic Acid; Amino Acid Sequence; Arabidopsis; Arabidopsis Proteins; Carbon-Sulfur Lyases; Cysteine; Molecular Sequence Data; Plants, Genetically Modified; Signal Transduction

2010
Probing the isoprenylcysteine carboxyl methyltransferase (Icmt) binding pocket: sulfonamide modified farnesyl cysteine (SMFC) analogs as Icmt inhibitors.
    Bioorganic & medicinal chemistry letters, 2011, May-01, Volume: 21, Issue:9

    Topics: Binding Sites; Cysteine; Enzyme Activation; Enzyme Inhibitors; Humans; Inhibitory Concentration 50; Molecular Structure; Protein Methyltransferases; Protein Processing, Post-Translational

2011
Farnesylthiosalicylic acid (salirasib) inhibits Rheb in TSC2-null ELT3 cells: a potential treatment for lymphangioleiomyomatosis.
    International journal of cancer, 2012, Mar-15, Volume: 130, Issue:6

    Topics: Animals; Cell Line, Tumor; Cell Movement; Cell Proliferation; Cysteine; Farnesol; Lymphangioleiomyomatosis; Lymphocytes, Null; Mice; Mice, Nude; Monomeric GTP-Binding Proteins; Mutation; Neuropeptides; Phosphorylation; Ras Homolog Enriched in Brain Protein; ras Proteins; Rats; Ribosomal Protein S6 Kinases; Salicylates; Tuberous Sclerosis Complex 2 Protein; Tumor Suppressor Proteins

2012
IgM-mediated autoimmune responses directed against multiple neoepitopes in depression: new pathways that underpin the inflammatory and neuroprogressive pathophysiology.
    Journal of affective disorders, 2011, Volume: 135, Issue:1-3

    Topics: Acetylcholine; Adult; Aged; Antibody Formation; Autoimmunity; Case-Control Studies; Cysteine; Depression; Depressive Disorder; DNA Damage; Epitopes; Fatigue; Fatty Acids; Female; Humans; Immunoglobulin M; Inflammation; Lipid Peroxidation; Male; Middle Aged; Myristic Acid; Negotiating; Nitric Oxide; Oxidative Stress; Palmitic Acid; Severity of Illness Index

2011
IgM-mediated autoimmune responses directed against anchorage epitopes are greater in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) than in major depression.
    Metabolic brain disease, 2012, Volume: 27, Issue:4

    Topics: Adult; Amino Acids; Analysis of Variance; Autoimmune Diseases; Cysteine; Depressive Disorder, Major; Enzyme-Linked Immunosorbent Assay; Epitopes; Fatigue Syndrome, Chronic; Female; Humans; Immunoglobulin M; Least-Squares Analysis; Male; Middle Aged; Myristic Acid; Nitric Oxide; Palmitic Acid; Phenylalanine

2012