cysteine has been researched along with s-allylmercaptocysteine in 49 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 6 (12.24) | 18.2507 |
| 2000's | 14 (28.57) | 29.6817 |
| 2010's | 22 (44.90) | 24.3611 |
| 2020's | 7 (14.29) | 2.80 |
| Authors | Studies |
|---|---|
| Lee, ES; Lin, R; Steiner, M | 1 |
| Anagnostou, A; Hooker, J; Sigounas, G; Steiner, M | 1 |
| Heber, D | 1 |
| Anagnostou, A; Hooker, JL; Li, W; Sigounas, G; Steiner, M | 1 |
| Itakura, Y; Kasuga, S; Matsura, T; Sumioka, I; Yamada, K | 1 |
| Chu, TC; Han, G; Han, P; Potter, DE | 1 |
| Bacich, DJ; Heston, WD; Huryk, RF; Pinto, JT; Qiao, C; Rivlin, RS; Schubert, KB; Suffoletto, BP; Xing, J | 1 |
| Glozman, S; Mirelman, D; Miron, T; Rabinkov, A; Weiner, L; Wilchek, M; Yavin, E | 1 |
| Delohery, T; Holt, PR; Kawabata, Y; Moss, SF; Murty, V; Pinto, JT; Rivlin, RS; Shirin, H; Soh, JW; Weinstein, IB | 1 |
| Matsura, T; Sumioka, I; Yamada, K | 1 |
| desBordes, C; Khan, F; Lea, MA; Randolph, VM; Rasheed, M; Shareef, A | 1 |
| Deguchi, A; Gundersen, GG; Palazzo, AF; Pinto, JT; Shirin, H; Soh, JW; Weinstein, IB; Xiao, D; Yoon, JT | 1 |
| Barrera, D; Castro, L; Chirino, YI; Hernández-Pando, R; Macías-Ruvalcaba, NA; Maldonado, PD; Medina-Campos, ON; Pedraza-Chaverrí, J; Salcedo, MI | 1 |
| Ariga, T; Fukao, T; Hosono, T; Ito, Y; Ogihara, J; Seki, T; Shiba, H | 1 |
| Cooper, AJ; Krasnikov, BF; Pinto, JT | 1 |
| Cheung, HW; Chu, Q; Feng, H; Ling, MT; Tsao, SW; Wang, X; Wong, YC | 1 |
| Cheung, HW; Chua, CW; Howard, EW; Ling, MT; Wang, X; Wong, YC | 1 |
| Chiu, YT; Chua, CW; Howard, EW; Lee, DT; Wang, X; Wong, YC | 1 |
| Lee, Y | 1 |
| Amariglio, N; Eliav, S; Horev-Azaria, L; Izigov, N; Jacob-Hirsch, J; Mirelman, D; Miron, T; Pri-Chen, S; Rabinkov, A; Savion, N; Wilchek, M | 1 |
| Kim, H; Kim, K; Lee, J; Lee, Y | 1 |
| Ching, YP; Fung, ML; Ling, MT; Liong, EC; Tipoe, GL; Xiao, J | 1 |
| Chen, H; Guo, Z; Liang, D; Lin, L; Qin, Y; Tong, L; Wang, R; Wong, YC; Zhai, X; Zhao, W; Zhong, Z | 1 |
| Ching, YP; Fung, ML; Liong, EC; Nanji, AA; Tipoe, GL; Xiao, J | 1 |
| Cai, HF; Hu, WN; Li, N; Tian, FM; Yan, JY; Zhang, JH | 1 |
| Parkin, KL; Xiao, H; Zhang, W | 1 |
| Chen, H; Fu, S; Geng, J; Jiang, Y; Jin, Y; Liu, D; Meng, X; Qu, H; Tong, D; Ye, S | 1 |
| Chan, YC; Chen, CY; Chen, KB; Hung, TC; Lee, WY | 1 |
| Lin, G; Wang, K; Zhang, H; Zhao, Z | 1 |
| Han, X; Hu, W; Liu, Y; Yan, J | 1 |
| Kodera, Y; Matsutomo, T | 1 |
| Chen, H; Jiang, S; Qu, X; Wong, Y; Wu, J; Zhang, F; Zhang, J; Zhao, S; Zhong, Z | 1 |
| Blackwell, TK; Hirata, D; Kodera, Y; Mizunuma, M; Ogawa, T | 1 |
| Cai, J; Cao, J; Li, S; Liu, G; Luan, Y; Qi, Q; Wang, K; Wang, Y; Zhang, F; Zhang, Y; Zhao, Z; Zhu, X | 1 |
| Jiang, X; Li, A; Li, S; Zhao, Z; Zhu, X | 1 |
| Feng, X; Jiang, X; Li, A; Li, S; Liu, Y; Sun, X; Sun, Y; Zhao, Z; Zhu, X | 1 |
| Cheng, L; Li, S; Sun, Y; Yang, G; Zhao, Z; Zhu, X | 1 |
| Cao, X; Dong, Z; Jiang, X; Yang, M; Zhang, D; Zhang, J; Zhao, Z | 1 |
| Li, S; Yang, L; Yang, M; Zhao, Z | 1 |
| Fujii, T; Kodera, Y; Matsutomo, T | 1 |
| Parkin, K; Tocmo, R | 1 |
| Lv, Y; So, KF; Wong, NK; Xiao, J | 1 |
| Li, A; Li, C; Mo, M; Sun, X; Zhao, Z | 1 |
| Dong, Z; Li, A; Li, C; Li, S; Mo, M; Sun, Y; Zhao, Z | 1 |
| Lee, YY; Liong, EC; Tipoe, GL; Xia, ZY; Xiao, J; Yu, Q | 1 |
| An, L; Sun, X; Zhao, J; Zhao, Z; Zhou, Y | 1 |
| Amin Nordin, S; Joseph, N; Nandagopal Ms, G; Subramanian, MS; Thilakavathy, K | 1 |
| Li, S; Li, W; Sun, S; Wang, J; Wang, X; Yang, G; Yuan, L | 1 |
| Kodera, Y; Kurita, M; Matsutomo, T | 1 |
3 review(s) available for cysteine and s-allylmercaptocysteine
| Article | Year |
|---|---|
Redox-sensitive proteins are potential targets of garlic-derived mercaptocysteine derivatives.
Topics: Animals; Colorectal Neoplasms; Cysteine; Garlic; Humans; Models, Animal; Oxidation-Reduction; Plant Extracts; Protein Processing, Post-Translational; Proteins; Stomach Neoplasms | 2006 |
Anti-cancer activities of S-allylmercaptocysteine from aged garlic.
Topics: Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Cysteine; Disease Models, Animal; Garlic; Humans; Molecular Structure; Neoplasms; Signal Transduction | 2019 |
Prevailing Knowledge on the Bioavailability and Biological Activities of Sulphur Compounds from Alliums: A Potential Drug Candidate.
Topics: Allium; Animals; Anti-Infective Agents; Antineoplastic Agents; Blood Platelets; Cysteine; Disulfides; Fibrinolysis; Garlic; Humans; Immunologic Factors; Neoplasms; Obesity; Phytochemicals; Plant Extracts; Solubility; Sulfoxides; Sulfur; Sulfur Compounds | 2020 |
46 other study(ies) available for cysteine and s-allylmercaptocysteine
| Article | Year |
|---|---|
Thioallyl compounds: potent inhibitors of cell proliferation.
Topics: Animals; Antineoplastic Agents; Aorta, Thoracic; CDC2 Protein Kinase; Cell Division; Cells, Cultured; Cysteine; Endothelium, Vascular; Garlic; GTPase-Activating Proteins; Humans; Kinetics; Muscle, Smooth, Vascular; Phosphoproteins; Phosphorylation; Phosphotyrosine; Plants, Medicinal; Protein Tyrosine Phosphatases; Proteins; Rats; Tyrosine; Umbilical Veins | 1994 |
S-allylmercaptocysteine inhibits cell proliferation and reduces the viability of erythroleukemia, breast, and prostate cancer cell lines.
Topics: Antineoplastic Agents; Breast Neoplasms; Cell Division; Cell Survival; Cysteine; Humans; Leukemia, Erythroblastic, Acute; Male; Prostatic Neoplasms; Tumor Cells, Cultured | 1997 |
The stinking rose: organosulfur compounds and cancer.
Topics: Antineoplastic Agents, Phytogenic; Cell Division; Cysteine; Garlic; Humans; Neoplasms; Plants, Medicinal | 1997 |
S-allylmercaptocysteine, a stable thioallyl compound, induces apoptosis in erythroleukemia cell lines.
Topics: Apoptosis; Cell Cycle; Cell Division; Cysteine; DNA; DNA Fragmentation; Dose-Response Relationship, Drug; Flow Cytometry; Garlic; Humans; Leukemia, Erythroblastic, Acute; Plants, Medicinal; Sulfhydryl Compounds; Thymidine; Tritium; Tumor Cells, Cultured | 1997 |
Mechanisms of protection by S-allylmercaptocysteine against acetaminophen-induced liver injury in mice.
Topics: Acetaminophen; Alanine Transaminase; Animals; Chemical and Drug Induced Liver Injury; Coenzymes; Cysteine; Cytochrome P-450 CYP2E1; Glucuronosyltransferase; Glutathione; Lipid Peroxidation; Liver; Liver Diseases; Male; Mice; Proteins; Sulfhydryl Compounds; Sulfotransferases; Ubiquinone; Vitamin E | 1998 |
Intraocular pressure lowering by S-allylmercaptocysteine in rabbits.
Topics: Administration, Topical; Animals; Aqueous Humor; Atrial Natriuretic Factor; Ciliary Body; Cysteine; Dose-Response Relationship, Drug; Intraocular Pressure; Iris; Norepinephrine; Ophthalmic Solutions; Phosphines; Pupil; Rabbits; Random Allocation; Sympathetic Nervous System | 1999 |
Alterations of prostate biomarker expression and testosterone utilization in human LNCaP prostatic carcinoma cells by garlic-derived S-allylmercaptocysteine.
Topics: Adenocarcinoma; Antigens, Neoplasm; Antigens, Surface; Biomarkers, Tumor; Carboxypeptidases; Cell Division; Culture Media; Cysteine; Drug Interactions; gamma-Glutamyl Hydrolase; Garlic; Glutamate Carboxypeptidase II; Growth Inhibitors; Humans; Male; Plants, Medicinal; Prostate-Specific Antigen; Prostatic Neoplasms; Receptors, Androgen; Secretory Rate; Testosterone; Tumor Cells, Cultured | 2000 |
S-Allylmercaptoglutathione: the reaction product of allicin with glutathione possesses SH-modifying and antioxidant properties.
Topics: Alcohol Dehydrogenase; Antioxidants; Chromatography, High Pressure Liquid; Cysteine; Disulfides; Enzyme Inhibitors; Garlic; Glutathione; Kinetics; Magnetic Resonance Spectroscopy; Papain; Plants, Medicinal; Sulfhydryl Compounds; Sulfinic Acids | 2000 |
Antiproliferative effects of S-allylmercaptocysteine on colon cancer cells when tested alone or in combination with sulindac sulfide.
Topics: Antineoplastic Agents; Apoptosis; Blotting, Western; Caspase 3; Caspases; Cell Cycle; Cell Division; Cysteine; Dose-Response Relationship, Drug; Enzyme Activation; G2 Phase; Garlic; Glutathione; HT29 Cells; Humans; In Situ Hybridization, Fluorescence; Isoenzymes; JNK Mitogen-Activated Protein Kinases; Kinetics; Mitogen-Activated Protein Kinases; Mitosis; Plants, Medicinal; Proto-Oncogene Proteins c-bcl-2; Sulindac; Tumor Cells, Cultured | 2001 |
Therapeutic effect of S-allylmercaptocysteine on acetaminophen-induced liver injury in mice.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Animals; Cysteine; Cytochrome P-450 CYP2E1; Glutathione; Glutathione Disulfide; HSP70 Heat-Shock Proteins; Liver; Male; Mice; Protective Agents | 2001 |
Induction of histone acetylation and inhibition of growth of mouse erythroleukemia cells by S-allylmercaptocysteine.
Topics: Acetylation; Acetyltransferases; Allyl Compounds; Animals; Antineoplastic Agents; Breast Neoplasms; Colonic Neoplasms; Cysteine; Disulfides; Electrophoresis, Polyacrylamide Gel; Female; Histone Acetyltransferases; Histone Deacetylases; Histones; Humans; Leukemia, Erythroblastic, Acute; Leupeptins; Mice; Saccharomyces cerevisiae Proteins; Sulfinic Acids; Tumor Cells, Cultured | 2002 |
Induction of apoptosis by the garlic-derived compound S-allylmercaptocysteine (SAMC) is associated with microtubule depolymerization and c-Jun NH(2)-terminal kinase 1 activation.
Topics: Animals; Apoptosis; Binding Sites; Caspase 3; Caspases; Cell Cycle; Cell Line, Tumor; Centrosome; Colonic Neoplasms; Cysteine; Enzyme Activation; Enzyme Inhibitors; Golgi Apparatus; Humans; Mice; Microtubules; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinase 8; Mitogen-Activated Protein Kinases; Mitosis; NIH 3T3 Cells; p38 Mitogen-Activated Protein Kinases; Tubulin | 2003 |
S-allylmercaptocysteine scavenges hydroxyl radical and singlet oxygen in vitro and attenuates gentamicin-induced oxidative and nitrosative stress and renal damage in vivo.
Topics: Aldehydes; Animals; Biomarkers; Body Weight; Carboxylic Acids; Cysteine; Dinitrophenols; Energy Intake; Free Radical Scavengers; Gentamicins; Hydroxyl Radical; Immunohistochemistry; Kidney Cortex; Kidney Diseases; Kidney Glomerulus; Kidney Tubules, Proximal; Male; Oxidation-Reduction; Oxidative Stress; Proteins; Rats; Rats, Wistar; Reactive Oxygen Species; Tyrosine; Urine | 2004 |
Diallyl trisulfide suppresses the proliferation and induces apoptosis of human colon cancer cells through oxidative modification of beta-tubulin.
Topics: Allyl Compounds; Animals; Antineoplastic Agents; Apoptosis; Blotting, Western; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Cell Separation; Cell-Free System; Chromatography, Liquid; Colonic Neoplasms; Cyclin B; Cyclin B1; Cysteine; Cytoplasm; Disulfides; DNA; Flow Cytometry; Fluorescent Antibody Technique, Indirect; Garlic; Humans; Inhibitory Concentration 50; Mice; Mice, Nude; Microtubules; Neoplasm Transplantation; Oxidative Stress; Oxygen; Peptides; Protein Binding; Sulfides; Time Factors; Tubulin | 2005 |
A novel anticancer effect of garlic derivatives: inhibition of cancer cell invasion through restoration of E-cadherin expression.
Topics: Antineoplastic Agents; Cadherins; Cell Line, Tumor; Cell Movement; Cell Proliferation; Collagen; Cysteine; Drug Combinations; Drug Design; Garlic; Humans; Inhibitory Concentration 50; Laminin; Neoplasm Invasiveness; Neoplasms; Proteoglycans | 2006 |
Garlic-derived S-allylmercaptocysteine is a novel in vivo antimetastatic agent for androgen-independent prostate cancer.
Topics: Androgens; Animals; Antineoplastic Agents; Antineoplastic Agents, Hormonal; Cysteine; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Drug Resistance, Neoplasm; Garlic; Green Fluorescent Proteins; Humans; Male; Mice; Mice, SCID; Neoplasm Metastasis; Prostatic Neoplasms; Transfection; Tumor Cells, Cultured; Xenograft Model Antitumor Assays | 2007 |
Evidence of a novel docetaxel sensitizer, garlic-derived S-allylmercaptocysteine, as a treatment option for hormone refractory prostate cancer.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Blotting, Western; Cadherins; Cell Division; Cell Line, Tumor; Cysteine; Docetaxel; Down-Regulation; Drug Synergism; Flow Cytometry; G2 Phase; Garlic; Gene Expression Regulation, Neoplastic; Humans; Immunohistochemistry; Male; Mice; Mice, Nude; Neoplasms, Experimental; Prostatic Neoplasms; Proto-Oncogene Proteins c-bcl-2; Taxoids; Transplantation, Heterologous; Tumor Stem Cell Assay; Up-Regulation | 2008 |
Induction of apoptosis by S-allylmercapto-L-cysteine, a biotransformed garlic derivative, on a human gastric cancer cell line.
Topics: Allium; Apoptosis; bcl-2-Associated X Protein; Caspase 3; Caspase 9; Caspases; Cell Cycle; Cell Differentiation; Cell Line, Tumor; Cell Proliferation; Cysteine; Cytochromes c; DNA Fragmentation; Dose-Response Relationship, Drug; Garlic; Humans; Immunoblotting; In Situ Nick-End Labeling; Mitochondria; Oncogene Protein p21(ras); Proto-Oncogene Proteins c-bcl-2; Reverse Transcriptase Polymerase Chain Reaction; Stomach Neoplasms; Tumor Suppressor Protein p53 | 2008 |
Allicin up-regulates cellular glutathione level in vascular endothelial cells.
Topics: Animals; Antioxidants; Aorta; Cattle; Cells, Cultured; Cysteine; Disulfides; Endothelial Cells; Glutamate-Cysteine Ligase; Glutathione; Heme Oxygenase-1; Humans; Oligonucleotide Array Sequence Analysis; Polymerase Chain Reaction; RNA, Messenger; Sulfinic Acids; Thioredoxin-Disulfide Reductase; Umbilical Veins; Up-Regulation | 2009 |
Anticancer activity of S-allylmercapto-L-cysteine on implanted tumor of human gastric cancer cell.
Topics: Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Base Sequence; Cell Line, Tumor; Cysteine; DNA Primers; Humans; Immunohistochemistry; In Situ Nick-End Labeling; Mice; Mice, Nude; Reverse Transcriptase Polymerase Chain Reaction; Stomach Neoplasms; Transplantation, Heterologous | 2011 |
S-allylmercaptocysteine reduces carbon tetrachloride-induced hepatic oxidative stress and necroinflammation via nuclear factor kappa B-dependent pathways in mice.
Topics: Alanine Transaminase; Animals; Antioxidants; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Cysteine; Female; Inflammation; Lipid Peroxidation; Liver; Male; Malondialdehyde; Mice; Mice, Inbred C57BL; NF-kappa B; Nitric Oxide; Oxidative Stress | 2012 |
S-allylmercaptocysteine effectively inhibits the proliferation of colorectal cancer cells under in vitro and in vivo conditions.
Topics: Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Blotting, Western; Caco-2 Cells; Caspase 3; Cell Line, Tumor; Cell Proliferation; Cell Survival; Colorectal Neoplasms; Cysteine; Dose-Response Relationship, Drug; Enzyme Activation; Humans; Luciferases, Firefly; Male; Mice; Poly (ADP-Ribose) Polymerase-1; Poly(ADP-ribose) Polymerases; Time Factors; Xenograft Model Antitumor Assays | 2011 |
Garlic-derived S-allylmercaptocysteine is a hepato-protective agent in non-alcoholic fatty liver disease in vivo animal model.
Topics: Animals; Blotting, Western; Cysteine; Cytochrome P-450 CYP2E1; Cytochrome P-450 CYP2E1 Inhibitors; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Fatty Liver; Female; Garlic; Inflammation; Lipogenesis; Liver; MAP Kinase Signaling System; NF-kappa B; Non-alcoholic Fatty Liver Disease; Oxidative Stress; Phosphorylation; Plant Extracts; Rats; Rats, Sprague-Dawley; Transcription Factor AP-1 | 2013 |
Apoptosis of human gastric cancer cells line SGC 7901 induced by garlic-derived compound S-allylmercaptocysteine (SAMC).
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Cell Line, Tumor; Cysteine; Garlic; Humans; MAP Kinase Signaling System; Stomach Neoplasms | 2013 |
Apoptosis in MCF-7 breast cancer cells induced by S-alkenylmercaptocysteine (CySSR) species derived from Allium tissues in combination with sodium selenite.
Topics: Allium; Annexin A5; Antineoplastic Agents; Apoptosis; bcl-2-Associated X Protein; bcl-Associated Death Protein; Caspase 6; Caspase 7; Cell Cycle Checkpoints; Cell Survival; Cysteine; Dose-Response Relationship, Drug; Drug Synergism; Female; Glycogen Synthase Kinase 3; Humans; MCF-7 Cells; Mitochondria; Plant Extracts; Proto-Oncogene Proteins c-akt; Signal Transduction; Sodium Selenite; Tumor Suppressor Protein p53 | 2014 |
S-allylmercaptocysteine promotes MAPK inhibitor-induced apoptosis by activating the TGF-β signaling pathway in cancer cells.
Topics: Apoptosis; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Proliferation; Cysteine; Drug Synergism; Gene Expression Regulation, Neoplastic; Hep G2 Cells; Humans; Liver Neoplasms; Protein Kinase Inhibitors; Signal Transduction; Transforming Growth Factor beta | 2014 |
Investigation of estrogen receptor (ESR1) for breast cancer from traditional Chinese medicine.
Topics: 5-Hydroxytryptophan; Binding Sites; Breast Neoplasms; Computational Biology; Computer Simulation; Crystallography, X-Ray; Cysteine; Databases, Factual; Drug Design; Estrogen Receptor alpha; Female; Humans; Ligands; Medicine, Chinese Traditional; Molecular Docking Simulation; Protein Binding; Protein Conformation; Proteins | 2014 |
Antitumor mechanisms of S-allyl mercaptocysteine for breast cancer therapy.
Topics: Antineoplastic Agents; Apoptosis; Breast Neoplasms; Cell Cycle; Cell Line, Tumor; Cell Survival; Cysteine; Female; Humans; MCF-7 Cells | 2014 |
Garlic-derived compound S-allylmercaptocysteine (SAMC) is active against anaplastic thyroid cancer cell line 8305C (HPACC).
Topics: Apoptosis; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Cysteine; Dose-Response Relationship, Drug; Garlic; Humans; Thyroid Carcinoma, Anaplastic | 2015 |
Development of an Analytic Method for Sulfur Compounds in Aged Garlic Extract with the Use of a Postcolumn High Performance Liquid Chromatography Method with Sulfur-Specific Detection.
Topics: Allyl Compounds; Chromatography, High Pressure Liquid; Cysteine; Disulfides; Garlic; Humans; Isomerism; Mass Spectrometry; Plant Extracts; Sulfur; Sulfur Compounds | 2016 |
Over-expression of survivin is a factor responsible for differential responses of ovarian cancer cells to S-allylmercaptocysteine (SAMC).
Topics: Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Blotting, Western; Cadherins; Caspase 3; Cell Line, Tumor; Cell Movement; Cell Proliferation; Cysteine; Female; Garlic; Gene Expression Regulation, Neoplastic; Humans; Inhibitor of Apoptosis Proteins; Integrin beta1; Mice, Inbred BALB C; Mice, Nude; Ovarian Neoplasms; Reverse Transcriptase Polymerase Chain Reaction; RNA Interference; Survivin; Tumor Stem Cell Assay; Xenograft Model Antitumor Assays | 2016 |
Natural thioallyl compounds increase oxidative stress resistance and lifespan in Caenorhabditis elegans by modulating SKN-1/Nrf.
Topics: Aging; Animals; Caenorhabditis elegans; Caenorhabditis elegans Proteins; Cysteine; DNA-Binding Proteins; Forkhead Transcription Factors; Garlic; Gene Expression Regulation; Longevity; Oxidative Stress; Reactive Oxygen Species; Signal Transduction; Transcription Factors | 2016 |
Inhibitory effects of S-allylmercaptocysteine against benzo(a)pyrene-induced precancerous carcinogenesis in human lung cells.
Topics: A549 Cells; Benzo(a)pyrene; Carcinogenesis; Cell Cycle; Cell Proliferation; Cysteine; Garlic; Humans; Lung; Lung Neoplasms; NF-kappa B; Precancerous Conditions; Reactive Oxygen Species; Signal Transduction; Superoxide Dismutase | 2016 |
S-Allylmercaptocysteine Attenuates Cisplatin-Induced Nephrotoxicity through Suppression of Apoptosis, Oxidative Stress, and Inflammation.
Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Apoptosis; Biomarkers; Cell Line, Tumor; Cell Survival; Cisplatin; Cysteine; Down-Regulation; Humans; Inflammation; Interleukin-1beta; Kidney; Male; NAD(P)H Dehydrogenase (Quinone); NF-E2-Related Factor 2; NF-kappa B; Oxidative Stress; Rats; Rats, Sprague-Dawley; Tumor Necrosis Factor-alpha; Up-Regulation | 2017 |
S-allylmercaptocysteine suppresses the growth of human gastric cancer xenografts through induction of apoptosis and regulation of MAPK and PI3K/Akt signaling pathways.
Topics: Animals; Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Cysteine; Dose-Response Relationship, Drug; Female; Humans; MAP Kinase Signaling System; Mice; Mice, Inbred BALB C; Mice, Nude; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Signal Transduction; Stomach Neoplasms; Treatment Outcome | 2017 |
Combination of rapamycin and garlic-derived S-allylmercaptocysteine induces colon cancer cell apoptosis and suppresses tumor growth in xenograft nude mice through autophagy/p62/Nrf2 pathway.
Topics: Animals; Antineoplastic Agents; Antioxidants; Apoptosis; Autophagy; Cell Line, Tumor; Cell Proliferation; Colonic Neoplasms; Cysteine; Down-Regulation; Garlic; HCT116 Cells; Humans; Mice; Mice, Inbred BALB C; Mice, Nude; NF-E2-Related Factor 2; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-bcl-2; RNA-Binding Proteins; Signal Transduction; Sirolimus; Transplantation, Heterologous; Xenograft Model Antitumor Assays | 2017 |
Determination of S-Allylmercaptocysteine in Rat Plasma by LC-MS/MS and its Application to a Pharmacokinetics Study.
Topics: Animals; Chromatography, Liquid; Cysteine; Drug Stability; Female; Limit of Detection; Linear Models; Male; Rats; Rats, Sprague-Dawley; Reproducibility of Results; Tandem Mass Spectrometry | 2018 |
S-allylmercaptocysteine attenuates posaconazole-induced adverse effects in mice through antioxidation and anti-inflammation.
Topics: Animals; Anti-Bacterial Agents; Anti-Inflammatory Agents; Antioxidants; Colon; Cysteine; Cytokines; Diarrhea; Drug-Related Side Effects and Adverse Reactions; Garlic; Humans; Inflammation Mediators; Intestinal Mucosa; Mice; Mice, Inbred Strains; Microspheres; Triazoles | 2018 |
Changes of S-Allylmercaptocysteine and γ-Glutamyl- S-allylmercaptocysteine Contents and Their Putative Production Mechanisms in Garlic Extract during the Aging Process.
Topics: Cysteine; Garlic; Kinetics; Plant Extracts; Time Factors | 2018 |
S-Alk(en)ylmercaptocysteine suppresses LPS-induced pro-inflammatory responses in murine macrophages through inhibition of NF-κB pathway and modulation of thiol redox status.
Topics: Animals; Anti-Inflammatory Agents; Buthionine Sulfoximine; Cysteine; Gene Expression Regulation; Glutamate-Cysteine Ligase; Glutathione; I-kappa B Kinase; Interleukin-1beta; Interleukin-6; Lipopolysaccharides; Mice; NF-E2-Related Factor 2; NF-kappa B; Nitric Oxide Synthase Type II; Oxidation-Reduction; Oxidative Stress; RAW 264.7 Cells; Signal Transduction; Tumor Necrosis Factor-alpha | 2018 |
S-Allylmercaptocysteine attenuates Bleomycin-induced pulmonary fibrosis in mice via suppressing TGF-β1/Smad and oxidative stress pathways.
Topics: Animals; Antioxidants; Bleomycin; Bronchoalveolar Lavage Fluid; Cysteine; Disease Models, Animal; Female; Humans; Mice; Mice, Inbred C57BL; Oxidative Stress; Pulmonary Fibrosis; Signal Transduction; Smad Proteins; Transforming Growth Factor beta1 | 2020 |
S-allylmercaptocysteine ameliorates lipopolysaccharide-induced acute lung injury in mice by inhibiting inflammation and oxidative stress via nuclear factor kappa B and Keap1/Nrf2 pathways.
Topics: Acute Lung Injury; Animals; Anti-Inflammatory Agents; Cysteine; Cytokines; Humans; Inflammation; Inflammation Mediators; Kelch-Like ECH-Associated Protein 1; Lipopolysaccharides; Male; Mice; Mice, Inbred BALB C; NF-E2-Related Factor 2; NF-kappa B; Oxidative Stress; Signal Transduction; Superoxide Dismutase | 2020 |
S-allylmercaptocysteine improves nonalcoholic steatohepatitis by enhancing AHR/NRF2-mediated drug metabolising enzymes and reducing NF-κB/IκBα and NLRP3/6-mediated inflammation.
Topics: Animals; Cysteine; Inflammation; Liver; Mice; NF-E2-Related Factor 2; NF-kappa B; NF-KappaB Inhibitor alpha; NLR Family, Pyrin Domain-Containing 3 Protein; Non-alcoholic Fatty Liver Disease; Pharmaceutical Preparations; Rats; Rats, Sprague-Dawley | 2021 |
S-allylmercaptocysteine inhibits mucin overexpression and inflammation via MAPKs and PI3K-Akt signaling pathways in acute respiratory distress syndrome.
Topics: Animals; Anti-Inflammatory Agents; Cell Line; Cysteine; Cytokines; Humans; Inflammation Mediators; Lipopolysaccharides; Lung; Mice, Inbred BALB C; Mitogen-Activated Protein Kinases; Mucin 5AC; Mucin-5B; Phosphatidylinositol 3-Kinase; Phosphorylation; Proto-Oncogene Proteins c-akt; Respiratory Distress Syndrome; Signal Transduction; Up-Regulation | 2020 |
S-Allylmercaptocysteine Targets Nrf2 in Osteoarthritis Treatment Through NOX4/NF-κB Pathway.
Topics: Animals; Antineoplastic Agents, Phytogenic; Cells, Cultured; Cysteine; Disease Models, Animal; Dose-Response Relationship, Drug; Male; Molecular Structure; NADPH Oxidase 4; NF-E2-Related Factor 2; NF-kappa B; Osteoarthritis; Rats; Rats, Sprague-Dawley; Structure-Activity Relationship | 2020 |
3-Allyltrisulfanyl-alanine Formation during the Preparation of Aged Garlic Extract.
Topics: Animals; Cysteine; Food Storage; Garlic; Interleukin-6; Lymphocytes; Mice; Plant Extracts; Time Factors | 2020 |