cysteine and s-adenosylmethionine

cysteine has been researched along with s-adenosylmethionine in 181 studies

Research

Studies (181)

TimeframeStudies, this research(%)All Research%
pre-199029 (16.02)18.7374
1990's27 (14.92)18.2507
2000's54 (29.83)29.6817
2010's56 (30.94)24.3611
2020's15 (8.29)2.80

Authors

AuthorsStudies
Giangregorio, N; Indiveri, C; Palmieri, F1
Bastin, J; Bennett, MJ; Chen, J; Doulias, PT; Ischiropoulos, H; Tenopoulou, M1
Console, L; De Palma, A; Giangregorio, N; Indiveri, C; Tonazzi, A1
Console, L; Giangregorio, N; Indiveri, C; Scalise, M; Tonazzi, A1
Butt, VS; Poulton, JE1
Chiba, T; Horiuchi, M; Koike, F1
Edwards, CH; Edwards, GA; Freeburne, MM; Jones, EG; Seo, CW; Sherman, L; Stacey, RE; Wade, WD1
Madison, JT; Thompson, JF1
Case, GL1
Friedhoff, AJ; Meller, E; Rosengarten, H1
Avram, D; Stan, R1
Barbey, R; Henry, D; Surdin-Kerjan, Y; Thomas, D1
Fullerton, FR; Hathcock, JN; Poirier, LA; Reicks, MM; Whittaker, P1
Koshland, DE; Lynch, BA1
Fujioka, M; Konishi, K1
Cañada, FJ; Pérez-Sala, D; Rando, RR; Tan, EW1
Friedman, S; Som, S1
Cherest, H; Surdin-Kerjan, Y; Thomas, D1
Anton, DL; Diaz, E1
Clarke, S; Fung, BK; Ota, IM; Yamane, HK1
Harris, CL1
Henning, SM; McKee, RW; Swendseid, ME1
Loo, G; Smith, JT1
Beachey, EH; Dale, JB; Kotb, M1
Djurhuus, R; Lillehaug, JR; Male, R; Svardal, AM; Ueland, PM1
Stipanuk, MH2
Dengler, HJ; Gugler, R1
Mardon, DN1
Kowalska, IM; Pieniazek, NJ; Stepień, PP1
Grabski, J; Paszewski, A1
Hill, LJ; Martin, WG1
Fujita, T; Suzuoki, Z1
Finkelstein, JD; Harris, B1
Ball, P; Breuer, H; Knuppen, R1
Ball, P; Breuer, H; Haupt, M; Knuppen, R2
Fitzgerald, PJ; Marsh, WH; Parsa, I1
Chow, CM; McConnell, WB; Nigam, SN1
Chen, SS; Duerre, JA; Walgate, JH1
Spence, KD1
Cooper, AJ1
Finkelstein, JD; Harris, BJ; Kyle, WE; Martin, JJ1
Döbeli, H; Nüesch, J1
Ozaki, H; Shiio, I1
Finta, C; Kiss, A; Patthy, A; Szilák, L; Venetianer, P2
Hattman, S; Kossykh, VG; Schlagman, SL1
Frey, PA; Lieder, KW; Reed, GH; Wu, W1
Bui, BT; Florentin, D; Izumi, Y; Marquet, A; Ohshiro, T; Yamamoto, M1
Argenzio, F; Aurilio, C; Coltorti, M; Del Vecchio Blanco, C; Grella, A; Loguercio, C; Nardi, G; Petrone, E1
Scott, WG; Stoddard, BL1
Brown, MS; Goldstein, JL; Seabra, MC; Smeland, TE1
Bui, BT; Florentin, D; Izumi, Y; Marquet, A; Ohshiro, T1
Caspers, P; Cesura, AM; da Prada, M; Karrer, C; Lahm, HW; Lang, G; Vilbois, F1
Huang, HY; Lu, SC1
Barrett, J; Walker, J1
Hüttermann, J; Kappl, R; Knappe, J; Külzer, R; Pils, T1
Fukuo, T; Hikita, K; Kaneda, N; Matsubara, K; Nagatsu, T; Naruse, Y1
Kim, SK; Kim, SY; Kim, YC1
Pegg, AE; Stanley, BA; Xiong, H1
Hansen, J; Johannesen, PF1
Ataullakhanov, FI; Banerjee, R; Martinov, MV; Mosharov, EV; Vitvitsky, VM1
Liu, Y; Santi, DV1
Danchin, A; Kung, HF; Sekowska, A1
Chen, W; Kennedy, DO; Kojima, A; Matsui-Yuasa, I1
Charlton, CG; Lamango, NS1
Finkelstein, JD1
Dyllick-Brenzinger, M; Liu, M; Taylor, DE; Turner, RJ; Winstone, TL1
Bhagwat, AS; Sharath, AN; Weinhold, E1
Goto, K; Ichioka, K; Iwama, T; Mizuno, Y; Yamagata, S1
Fukuda, EK; Hartman, TG; Hiserodt, RD; Lech, J; Rosen, RT; Rosen, SL; Ruiz, RJ; Zhou, Z1
Fontecave, M; Mulliez, E; Padovani, D1
Chango, A; James, SJ; Melnyk, S; Pogribna, M; Pogribny, I; Yi, P1
Goodman, JE; Helzlsouer, KJ; Lavigne, JA; Selhub, J; Strickland, PT; Wu, K; Yager, JD1
Marquet, A1
Fontecave, M; Hewitson, KS; Münck, E; Ollagnier-de Choudens, S; Roach, P; Sanakis, Y1
Arima, K; Asada, T; Eto, K; Kimura, H; Makifuchi, T1
Eto, K; Kimura, H1
Borchardt, RT; Ewing, GJ; Miles, RW; Nielsen, LP; Robins, MJ; Yin, D1
Balaña-Fouce, R; García-Estrada, C; Ordóñez, D; Pajares, MA; Pérez-Pertejo, Y; Reguera, RM; Villa, H1
Carmel, R; James, SJ; Melnyk, S1
Bellas, R; Harrington, EO; Kramer, K; Lu, Q; Newton, J; Rounds, S; Sheahan, KL1
Markham, GD; Taylor, JC1
Appling, DR; Chan, SY1
Ahmad, A; Allen, RH; Panayiotidis, MI; Stabler, SP; White, CW1
Dierks, T; Fang, Q; Peng, J1
Leonardi, R; Roach, PL1
Booker, SJ; Iwig, DF1
Cutler, P; Gaylor, DW; James, SJ; Janak, L; Jernigan, S; Melnyk, S; Neubrander, JA1
Allen, R; Boger, R; Doshi, S; Goodfellow, J; Lewis, M; McDowell, I; Moat, S; Newcombe, R; Stabler, S1
Amanlou, M; Dehghani, M; Dehpour, AR; Ebrahimkhani, MR; Farsam, H; Honar, H; Kiani, S; Mirazi, N; Pasalar, P; Payabvash, S; Riazi, K; Sadeghipour, H1
Fowler, B; Herrmann, W; Kuhlmann, MK; Makowski, J; Obeid, R; Schorr, H1
Jung, YS; Kim, SK; Kim, YC1
Kim, SK; Kim, YC1
Breckau, D; Grage, K; Heathcote, P; Jahn, D; Jahn, M; Layer, G; Masoumi, A; Schünemann, V; Teschner, T; Trautwein, AX1
Artillo, R; Carreras, O; Murillo, ML; Murillo-Fuentes, ML; Ubeda, N; Varela-Moreiras, G1
Brick, P; Fairhurst, SA; Lowe, DJ; Onesti, S; Paraskevopoulou, C1
Baudouin-Cornu, P; Menant, A; Peyraud, C; Thomas, D; Tyers, M1
Brosnan, JT; Brosnan, ME1
Fernstrom, JD; Mudd, SH1
Frank, N; Kery, V; Kraus, JP; Maclean, KN1
Burrin, DG; Stoll, B1
Amanlou, M; Dehpour, AR; Ghahremani, MH; Goliaei, A; Mandegary, A; Payabvash, S; Shafaroodi, H1
Morita, T; Okawa, H; Sugiyama, K1
Bai, L; Fen, M; Shi, X; Zhang, X; Zhou, P1
Benjdia, A; Berteau, O; Johnson, MK; Leprince, J; Subramanian, S; Vaudry, H2
Le Trong, I; Parson, WW; Rutherford, K; Stenkamp, RE1
Chang, CC; Chang, JH; Chien, YW; Huang, SY; Tsen, JH; Yang, HT1
Blom, H; Linnebank, M; Moskau, S; Semmler, A; Smith, D; Smulders, Y; Struys, E1
Agrawal, N; Banerjee, R1
Mori, M; Morita, T; Ohuchi, S; Sugiyama, K1
Nielsen, FH1
Allen, RH; O'Neill, HC; Sekhar, J; Stabler, SP; White, CW1
Kuchenreuther, JM; Stapleton, JA; Swartz, JR1
Adryanczyk, G; Cuiné, S; Lamouroux, C; Pignol, D; Roustan, C; Sabaty, M1
Ding, JG; Fu, RQ; Hong, L; Sun, QF; Wang, JR; Wang, XF; Wu, JG; Xu, DZ; Xu, XJ; Yang, JX1
Ali, V; Husain, A; Jeelani, G; Mi-ichi, F; Nozaki, T; Sato, D; Soga, T; Suematsu, M1
Geng, Z; Hu, X; Li, X; Song, X; Wang, Z; Zhang, X; Zhao, Q1
Chen, SY; Chen, YM; Chiang, EP; Tang, FY; Wang, YC1
Ahlum, JH; Benner, JS; Booker, SJ; Grove, TL; Krebs, C; Landgraf, BJ; Radle, MI1
Jeltsch, A; Jurkowska, RZ; Jurkowski, TP; Siddique, AN1
Boal, AK; Booker, SJ; Grove, TL; McLaughlin, MI; Rosenzweig, AC; Yennawar, NH1
Stubbe, J1
Han, YZ; Ren, ZM; Yu, DN; Zhang, WJ1
Dilger, RN; Garrow, TA; Gupta, S; Kruger, WD; Li, L; Strakova, J; Tryon, K1
Li, L1
Burghaus, O; Flühe, L; Gattner, MJ; Knappe, TA; Linne, U; Marahiel, MA; Schäfer, A1
Francke, C; Liu, M; Nauta, A; Prakash, C; Siezen, RJ1
David, LL; Davies, MJ; Friedrich, MG; Hooi, MY; Jamie, JF; Lyons, B; Mizdrak, J; Truscott, RJ; Wilmarth, PA1
Geisel, J; Gortner, L; Hartmuth, K; Herrmann, W; Nijhout, HF; Obeid, R; Reed, MC; Rohrer, TR1
Armengaud, J; Atta, M; Berggren, G; Clemancey, M; Douki, T; Fontecave, M; Gambarelli, S; Garcia-Serres, R; Kathirvelu, V; Latour, JM; Maurel, V; Mulliez, E; Perche-Letuvée, P1
Asgher, M; Fatma, M; Iqbal, N; Khan, MI; Khan, NA; Masood, A1
Kang, KW; Kim, SK; Kwak, HC; Lee, JY; Oh, SJ; Phuong, NT; Ryu, CS1
Kang, JS; Kim, BH; Kim, SK; Lee, CH; Lee, HS; Lee, JY; Noh, JR; Park, SK; Ryu, CS; Yun, KU1
Cole, D; Cox, SE; da Costa, KA; Dominguez-Salas, P; Dyer, RA; Fulford, AJ; Hennig, BJ; Innis, SM; Moore, SE; Prentice, AM; Waterland, RA; Zeisel, SH1
Devlin, AM; Glier, MB; Green, TJ1
Li, L; Yang, L1
Challand, MR; Driesener, RC; Kay, CW; Roach, PL; Salvadori, E; Spencer, J1
Dekker, JM; Drevon, CA; Elshorbagy, AK; Nijpels, G; Nurk, E; Nygård, O; Refsum, H; Stehouwer, CD; Teerlink, T; Tell, GS; Ueland, PM; Vinknes, KJ; Vollset, SE1
da Cunha, SF; de Freitas, EC; Deminice, R; Franco, GS; Jordao, AA; Rosa, FT1
Moresco, JJ; Rine, J; Sadhu, MJ; Yates, JR; Zimmer, AD1
Al-Mughairy, S; Deth, RC; Hodgson, NW; Shah, JS; Simms, B; Trivedi, MS; Trooskens, GA; Van Criekinge, W1
Diver, MM; Long, SB1
Sun, GX; Wang, PP; Zhu, YG1
Kim, SK; Kim, YM; Kwak, HC; Oh, SJ1
Bhatia, P; Singh, N1
Anilkumar, N; Brandes, RP; Brewer, AC; Burr, S; Caldwell, A; Dew, T; Dong, X; Halket, J; Hughes, RD; Martin, D; Mistry, RK; Murray, TV; Quaglia, A; Sawyer, GJ; Schröder, K; Shah, AM; Sherwood, R1
Fontecilla-Camps, JC; Martin, L; Nicolet, Y; Pagnier, A; Zeppieri, L1
Britt, RD; Bürstel, I; Cramer, SP; Pham, CC; Suess, DL; Swartz, JR1
Bandarian, V; Britt, RD; Bruender, NA; Wilcoxen, J1
Deth, R; Hodgson, N; Trivedi, M; Zhang, Y1
Boal, AK; Booker, SJ; Grove, TL; Schwalm, EL1
Amara, P; Benjdia, A; Berteau, O; Favier, A; Fontecilla-Camps, JC; Martin, L; Mouesca, JM; Nicolet, Y; Rohac, R; Ruffié, P1
Magwamba, CC; Palittapongarnpim, P; Rukseree, K1
Chen, J; Jiang, X; Li, J; Rosen, BP1
Kuang, Z; Sutter, BM; Tu, BP; Wang, Y; Ye, C1
Bandarian, V; Nelp, MT; Stepanski, BM; Young, AP1
Blaszczyk, AJ; Booker, SJ; Wang, RX1
Ereño-Orbea, J; Giménez-Mascarell, P; Klaudiny, J; Kraus, JP; Majtan, J; Majtan, T; Martínez-Cruz, LA; Oyenarte, I1
Diver, MM; Koide, A; Koide, S; Long, SB; Pedi, L1
Bin, P; Huang, R; Zhou, X1
Chu, T; Fujimori, DG; Stojković, V; Therizols, G; Weinberg, DE1
Bauerle, MR; Booker, SJ; Grove, TL1
Ayikpoe, R; Bonitatibus, S; Eaton, GR; Eaton, SS; Elliott, SJ; Langton, M; Latham, JA; Ngendahimana, T; Pandelia, ME; Walker, LM1
Broderick, JB; Copié, V; Galambas, A; Jones, M; Lukes, M; McDaniel, E; Miller, J; Shepard, EM; Szilagyi, RK; Watts, H1
Corrales, F; Franco, L; Guerrero, L; López-Rodas, G; Martí-Andrés, P; Paradela, A; Pérez, S; Rius-Pérez, S; Sastre, J; Taléns-Visconti, R; Torres, L; Torres-Cuevas, I1
Berisa, M; Cross, JR; Qin, W; Schwörer, S; Thompson, CB; Zhu, J1
Echavarri-Erasun, C; Fajardo, AS; Legrand, P; Martin, L; Nicolet, Y; Payá-Tormo, LA; Pellicer Martı Nez, MT; Rubio, LM; Vernède, X1
Kožich, V; Stabler, S1
Elango, R1
Deutz, NEP; Engelen, MPKJ; Indika, NR; Peiris, H; Perera, R; Wijetunge, S1
Eguchi, T; Kudo, F; Rohmer, M; Sato, S1
Bailey, CA; Cáceres, JC; Greene, BL; Yokoyama, K1
Chen, Y; Chen, Z; Hou, X; Ko, Y; Liu, HW; Ruszczycky, MW; Zhang, J; Zhou, J1
Fujii, J; Homma, T; Kobayashi, S1
Bandyopadhyay, P; Biswas, R; Dutta, S; Laxman, S; Pramanick, I; Ps, S; Rajmani, RS; Singh, A; Singh, S; Sreedharan, S1
Chen, K; Gong, J; Liu, F; Peng, Y; Qiao, Y; Si, C; Song, F; Wang, P; Wang, X; Zhou, H1
Chen, J; Cui, X; Fang, N; Wu, Y; Xiao, D; Yu, S1
Bruemmer, KJ; Chang, CJ; Dingler, FA; Esteller, M; Garcia-Prieto, CA; Ge, EJ; Ingolia, NT; Millington, CL; Nomura, DK; Patel, KJ; Pham, VN; Pontel, LB; Pulos-Holmes, MC; Tenney, L; Toh, JDW; Ward, CC1

Reviews

17 review(s) available for cysteine and s-adenosylmethionine

ArticleYear
Metabolism of sulfur-containing amino acids.
    Annual review of nutrition, 1986, Volume: 6

    Topics: Adenosylhomocysteinase; Animals; Carboxy-Lyases; Cysteine; Female; Homocysteine; Humans; Hydrolases; Isoenzymes; Liver; Male; Methionine; Methionine Adenosyltransferase; Methylation; Polyamines; S-Adenosylhomocysteine; S-Adenosylmethionine; Sulfur; Taurine; Transaminases

1986
Biochemistry of sulfur-containing amino acids.
    Annual review of biochemistry, 1983, Volume: 52

    Topics: Adenosine; Amino Acid Metabolism, Inborn Errors; Animals; Cysteine; Deoxyadenosines; Homocysteine; Humans; Methionine; Oxidoreductases; Oxidoreductases Acting on Sulfur Group Donors; S-Adenosylmethionine; Structure-Activity Relationship; Sulfur; Sulfurtransferases; Thionucleosides; Thiosulfate Sulfurtransferase

1983
Parasite sulphur amino acid metabolism.
    International journal for parasitology, 1997, Volume: 27, Issue:8

    Topics: Amino Acids, Sulfur; Animals; Cystathionine; Cysteine; Deoxyadenosines; Eukaryota; Helminthiasis; Helminths; Humans; Methionine; Protozoan Infections; S-Adenosylmethionine; Thionucleosides

1997
Sulfur metabolism in Escherichia coli and related bacteria: facts and fiction.
    Journal of molecular microbiology and biotechnology, 2000, Volume: 2, Issue:2

    Topics: Amino Acid Sequence; Bacillus subtilis; Bacterial Proteins; Biological Transport, Active; Cysteine; Escherichia coli; Genes, Bacterial; Methionine; Methylation; Molecular Sequence Data; Oxidation-Reduction; S-Adenosylmethionine; Selenium; Sulfonic Acids; Sulfur

2000
Pathways and regulation of homocysteine metabolism in mammals.
    Seminars in thrombosis and hemostasis, 2000, Volume: 26, Issue:3

    Topics: Animals; Cystathionine; Cystathionine beta-Synthase; Cystathionine gamma-Lyase; Cysteine; Heme; Homocysteine; Isoenzymes; Kinetics; Mammals; Methionine; Methionine Adenosyltransferase; Organ Specificity; Oxidation-Reduction; Pyridoxal Phosphate; S-Adenosylhomocysteine; S-Adenosylmethionine; Sulfur; Tetrahydrofolates

2000
Enzymology of carbon-sulfur bond formation.
    Current opinion in chemical biology, 2001, Volume: 5, Issue:5

    Topics: Acetyltransferases; Anaerobiosis; Bacterial Proteins; Biotin; Cysteine; Enzymes; Intramolecular Transferases; Iron-Sulfur Proteins; Models, Chemical; S-Adenosylmethionine; Sulfur; Sulfurtransferases

2001
The sulfur-containing amino acids: an overview.
    The Journal of nutrition, 2006, Volume: 136, Issue:6 Suppl

    Topics: Allosteric Regulation; Amino Acids, Sulfur; Animals; Cysteine; Gene Expression Regulation; Homocysteine; Humans; Methionine; Proteins; S-Adenosylmethionine; Taurine

2006
Emerging aspects of gut sulfur amino acid metabolism.
    Current opinion in clinical nutrition and metabolic care, 2007, Volume: 10, Issue:1

    Topics: Amino Acids, Sulfur; Biological Availability; Cysteine; DNA Methylation; Gastrointestinal Diseases; Homocysteine; Humans; Intestinal Absorption; Intestinal Mucosa; Methionine; Nutritional Physiological Phenomena; Oxidation-Reduction; S-Adenosylmethionine

2007
Mechanistic studies of the radical SAM enzyme spore photoproduct lyase (SPL).
    Biochimica et biophysica acta, 2012, Volume: 1824, Issue:11

    Topics: Amino Acid Motifs; Bacillus subtilis; Bacterial Proteins; Binding Sites; Biocatalysis; Cysteine; DNA Repair; DNA, Bacterial; Free Radicals; Iron-Sulfur Proteins; Models, Molecular; Proteins; S-Adenosylmethionine; Thymine; Ultraviolet Rays

2012
Cross-talk between sulfur assimilation and ethylene signaling in plants.
    Plant signaling & behavior, 2013, Volume: 8, Issue:1

    Topics: Cysteine; Ethylenes; Glutathione; Plants; S-Adenosylmethionine; Sulfur

2013
Methyl nutrients, DNA methylation, and cardiovascular disease.
    Molecular nutrition & food research, 2014, Volume: 58, Issue:1

    Topics: Amino Acids; Atherosclerosis; Cardiovascular Diseases; Cysteine; Diet; DNA Methylation; Epigenesis, Genetic; Folic Acid; Humans; Hyperhomocysteinemia; Lipid Metabolism; Methionine; Nutritional Status; Risk Factors; S-Adenosylmethionine; Vitamin B Complex

2014
Homocysteine excess: delineating the possible mechanism of neurotoxicity and depression.
    Fundamental & clinical pharmacology, 2015, Volume: 29, Issue:6

    Topics: Cysteine; Depression; Homocysteine; Humans; Hyperhomocysteinemia; Neurotoxicity Syndromes; S-Adenosylmethionine

2015
Oxidation Resistance of the Sulfur Amino Acids: Methionine and Cysteine.
    BioMed research international, 2017, Volume: 2017

    Topics: Amino Acids, Sulfur; Antioxidants; Cysteine; Glutathione; Hydrogen Sulfide; Methionine; Oxidation-Reduction; Reactive Oxygen Species; S-Adenosylmethionine; Taurine

2017
Metabolism of Sulfur-Containing Amino Acids: How the Body Copes with Excess Methionine, Cysteine, and Sulfide.
    The Journal of nutrition, 2020, 10-01, Volume: 150, Issue:Suppl 1

    Topics: Amino Acid Metabolism, Inborn Errors; Amino Acids; Animals; Cystathionine beta-Synthase; Cysteine; Glycine N-Methyltransferase; Homocysteine; Humans; Hydrogen Sulfide; Liver; Methionine; S-Adenosylmethionine; Serine; Sulfides; Sulfur; Thiosulfates

2020
Lessons Learned from Inherited Metabolic Disorders of Sulfur-Containing Amino Acids Metabolism.
    The Journal of nutrition, 2020, 10-01, Volume: 150, Issue:Suppl 1

    Topics: Amino Acids, Sulfur; Animals; Brain Diseases; Cysteine; Glutathione; Homocysteine; Homocystinuria; Humans; Hydrogen Sulfide; Liver; Metabolic Diseases; Metabolism, Inborn Errors; Methionine; Methionine Adenosyltransferase; Methylation; S-Adenosylmethionine; Sulfites; Sulfur; Sulfur Compounds

2020
Methionine Nutrition and Metabolism: Insights from Animal Studies to Inform Human Nutrition.
    The Journal of nutrition, 2020, 10-01, Volume: 150, Issue:Suppl 1

    Topics: Animals; Betaine; Choline; Creatine; Cysteine; Diet; Folic Acid; Glutathione; Homocysteine; Humans; Methionine; Methylation; Models, Animal; Nutritional Requirements; Nutritional Status; Phosphatidylcholines; S-Adenosylmethionine; Sulfur

2020
Sulfur amino acid metabolism and related metabotypes of autism spectrum disorder: A review of biochemical evidence for a hypothesis.
    Biochimie, 2021, Volume: 184

    Topics: Autism Spectrum Disorder; Brain; Coenzymes; Cysteine; Humans; Metalloproteins; Molybdenum Cofactors; Oxidative Stress; Pteridines; S-Adenosylmethionine

2021

Trials

4 trial(s) available for cysteine and s-adenosylmethionine

ArticleYear
Effect of S-adenosyl-L-methionine administration on red blood cell cysteine and glutathione levels in alcoholic patients with and without liver disease.
    Alcohol and alcoholism (Oxford, Oxfordshire), 1994, Volume: 29, Issue:5

    Topics: Adult; Alcoholism; Cysteine; Erythrocytes; Glutathione; Humans; Liver Cirrhosis, Alcoholic; Liver Function Tests; Male; Middle Aged; S-Adenosylmethionine

1994
Relationship between S-adenosylmethionine, S-adenosylhomocysteine, asymmetric dimethylarginine, and endothelial function in healthy human subjects during experimental hyper- and hypohomocysteinemia.
    Metabolism: clinical and experimental, 2005, Volume: 54, Issue:3

    Topics: Acetylcysteine; Adult; Arginine; Blood Flow Velocity; Brachial Artery; Cross-Over Studies; Cystathionine; Cysteine; Dipeptides; Double-Blind Method; Endothelium, Vascular; Female; Homocysteine; Humans; Hyperhomocysteinemia; Kinetics; Male; Methionine; Placebos; S-Adenosylhomocysteine; S-Adenosylmethionine; Vasodilation

2005
Efficacy and safety of intravenous stronger neo-minophagen C and S-adenosyl-L-methionine in treatment of pregnant woman with chronic hepatitis B: a pilot study.
    Medical science monitor : international medical journal of experimental and clinical research, 2010, Volume: 16, Issue:8

    Topics: Adult; Alanine Transaminase; Antiviral Agents; Aspartate Aminotransferases; Cysteine; Demography; Drug Combinations; Drug Therapy, Combination; Embryonic Development; Female; Follow-Up Studies; Glycine; Glycyrrhetinic Acid; Health; Hepatitis B, Chronic; Humans; Infant, Newborn; Injections, Intravenous; Liver Function Tests; Pilot Projects; Pregnancy; S-Adenosylmethionine; Treatment Outcome

2010
Short-term creatine supplementation does not reduce increased homocysteine concentration induced by acute exercise in humans.
    European journal of nutrition, 2014, Volume: 53, Issue:6

    Topics: Adolescent; Creatine; Cysteine; Dietary Supplements; Double-Blind Method; Energy Intake; Exercise; Feeding Behavior; Folic Acid; Glycine; Healthy Volunteers; Homocysteine; Humans; Male; Methionine; S-Adenosylmethionine; Soccer; Vitamin B 12

2014

Other Studies

160 other study(ies) available for cysteine and s-adenosylmethionine

ArticleYear
Glutathione controls the redox state of the mitochondrial carnitine/acylcarnitine carrier Cys residues by glutathionylation.
    Biochimica et biophysica acta, 2013, Volume: 1830, Issue:11

    Topics: Animals; Biological Transport; Carnitine; Carrier Proteins; Cysteine; Glutaredoxins; Glutathione; Glutathione Disulfide; Mitochondria, Liver; Mutagenesis, Site-Directed; Oxidation-Reduction; Proteolipids; Rats

2013
Strategies for correcting very long chain acyl-CoA dehydrogenase deficiency.
    The Journal of biological chemistry, 2015, Apr-17, Volume: 290, Issue:16

    Topics: Acetylcysteine; Acyl-CoA Dehydrogenase; Acyl-CoA Dehydrogenase, Long-Chain; Amino Acid Sequence; Carnitine; Congenital Bone Marrow Failure Syndromes; Cysteine; Dose-Response Relationship, Drug; Fatty Acids; Fibroblasts; Genetic Therapy; Humans; Kinetics; Lipid Metabolism, Inborn Errors; Mitochondrial Diseases; Molecular Sequence Data; Muscular Diseases; Mutation; Oxidation-Reduction; Primary Cell Culture; Skin

2015
Nitric oxide inhibits the mitochondrial carnitine/acylcarnitine carrier through reversible S-nitrosylation of cysteine 136.
    Biochimica et biophysica acta. Bioenergetics, 2017, Volume: 1858, Issue:7

    Topics: Amino Acid Sequence; Animals; Biological Transport; Carnitine; Carnitine Acyltransferases; Conserved Sequence; Cysteine; Dithioerythritol; Liposomes; Mitochondria; Models, Molecular; Nitric Oxide; Nitric Oxide Donors; Nitrogen; Oxidation-Reduction; Protein Conformation; Protein Processing, Post-Translational; Rats; S-Nitrosoglutathione; Sequence Alignment; Sequence Homology, Amino Acid

2017
Inhibition of the Mitochondrial Carnitine/Acylcarnitine Carrier by Itaconate through Irreversible Binding to Cysteine 136: Possible Pathophysiological Implications.
    Biomolecules, 2023, 06-15, Volume: 13, Issue:6

    Topics: Carnitine; Cysteine; HeLa Cells; Humans; Membrane Transport Modulators; Membrane Transport Proteins; Mitochondria

2023
Purification and properties of S-adenosyl-L-homocysteine hydrolase from leaves of spinach beet.
    Archives of biochemistry and biophysics, 1976, Volume: 172, Issue:1

    Topics: Adenine; Cysteine; Deoxyadenosines; Homocysteine; Hydrogen-Ion Concentration; Hydrolases; Kinetics; Methionine; Plants; S-Adenosylhomocysteine; S-Adenosylmethionine

1976
[Effect of thiol compounds on experimental liver damage (IV). Detoxicating effect of tiopronin, glutathione and cysteine on ethionine induced lived damage (author's transl)].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1979, Volume: 75, Issue:7

    Topics: Alanine Transaminase; Amino Acids, Sulfur; Animals; Antidotes; Chemical and Drug Induced Liver Injury; Cysteine; Ethionine; Female; Glutathione; In Vitro Techniques; Liver; Rats; S-Adenosylmethionine; Sulfhydryl Compounds; Tiopronin

1979
Formation of methionine from alpha-amino-n-butyric acid and 5'-methylthioadenosine in the rat.
    The Journal of nutrition, 1977, Volume: 107, Issue:10

    Topics: Adenosine; Aminobutyrates; Animals; Body Weight; Butyrates; Choline; Cysteine; Deoxyadenosines; Homoserine; Male; Methionine; Rats; S-Adenosylmethionine; Thionucleosides

1977
Threonine synthetase from higher plants: stimulation by S-adenosylmethionine and inhibition by cysteine.
    Biochemical and biophysical research communications, 1976, Jul-26, Volume: 71, Issue:2

    Topics: Cysteine; Enzyme Activation; Kinetics; Lyases; Plants; S-Adenosylmethionine

1976
Evidence for S-adenosylmethionine independent catabolism of methionine in the rat.
    The Journal of nutrition, 1976, Volume: 106, Issue:12

    Topics: Animals; Carbon Dioxide; Cysteine; Formaldehyde; Formates; Glycine; Liver; Male; Methionine; Rats; S-Adenosylmethionine; Serine

1976
Synthesis of tetrahydro-beta-carbolines from indoleamines via enzymatic formation of formaldehyde from 5-methyltetrahydrofolic acid.
    Biochemical pharmacology, 1975, Oct-01, Volume: 24, Issue:19

    Topics: Animals; Brain; Carbolines; Chromatography, Thin Layer; Cysteine; Formaldehyde; In Vitro Techniques; Indoles; Lung; Methylation; Rabbits; Rats; S-Adenosylmethionine; Serotonin; Tetrahydrofolates; Tryptamines

1975
Ergosterol levels in two L-methionine-enriched mutants of the methylotrophic yeast Candida boidinii ICCF26.
    FEMS microbiology letters, 1992, Nov-01, Volume: 77, Issue:1-3

    Topics: Candida; Cysteine; Ergosterol; Methionine; Mutagenesis; S-Adenosylmethionine

1992
Physiological analysis of mutants of Saccharomyces cerevisiae impaired in sulphate assimilation.
    Journal of general microbiology, 1992, Volume: 138, Issue:10

    Topics: Cysteine; Genes, Fungal; Homocysteine; Methionine; Mutation; Oxidation-Reduction; Oxidoreductases Acting on Sulfur Group Donors; S-Adenosylmethionine; Saccharomyces cerevisiae; Sulfates; Sulfides; Sulfites; Thiosulfates

1992
Prolonged acetaminophen ingestion by mice fed a methionine-limited diet does not affect iron-induced liver lipid peroxidation or S-adenosylmethionine.
    The Journal of nutrition, 1992, Volume: 122, Issue:8

    Topics: Acetaminophen; Animals; Cysteine; Glutathione; Glutathione Peroxidase; Iron; Lipid Peroxidation; Liver; Male; Methionine; Mice; S-Adenosylhomocysteine; S-Adenosylmethionine; Superoxide Dismutase

1992
Disulfide cross-linking studies of the transmembrane regions of the aspartate sensory receptor of Escherichia coli.
    Proceedings of the National Academy of Sciences of the United States of America, 1991, Dec-01, Volume: 88, Issue:23

    Topics: Amino Acid Sequence; Aspartic Acid; Cell Membrane; Chemotaxis; Cross-Linking Reagents; Cysteine; Disulfides; Escherichia coli; Models, Structural; Molecular Sequence Data; Mutagenesis, Site-Directed; Protein Conformation; Receptors, Amino Acid; Receptors, Cell Surface; S-Adenosylmethionine

1991
Reversible inactivation of recombinant rat liver guanidinoacetate methyltransferase by glutathione disulfide.
    Archives of biochemistry and biophysics, 1991, Aug-15, Volume: 289, Issue:1

    Topics: Adenosine; Animals; Cysteine; Enzyme Activation; Enzyme Reactivators; Ethylmaleimide; Glutathione; Glutathione Disulfide; Glycine; Guanidinoacetate N-Methyltransferase; Iodoacetates; Iodoacetic Acid; Kinetics; Liver; Mercaptoethanol; Methyltransferases; Oxidation-Reduction; Rats; Recombinant Proteins; S-Adenosylmethionine; Spectrum Analysis; Sulfhydryl Compounds

1991
Methylation and demethylation reactions of guanine nucleotide-binding proteins of retinal rod outer segments.
    Proceedings of the National Academy of Sciences of the United States of America, 1991, Apr-15, Volume: 88, Issue:8

    Topics: Acetylcysteine; Adenosine; Animals; Cattle; Cysteine; GTP-Binding Proteins; In Vitro Techniques; Methylation; Molecular Weight; Rod Cell Outer Segment; S-Adenosylhomocysteine; S-Adenosylmethionine; Signal Transduction; Transducin

1991
Identification of a highly conserved domain in the EcoRII methyltransferase which can be photolabeled with S-adenosyl-L-[methyl-3H]methionine. Evidence for UV-induced transmethylation of cysteine 186.
    The Journal of biological chemistry, 1991, Feb-15, Volume: 266, Issue:5

    Topics: Amino Acid Sequence; Chromatography, Gel; Chromatography, High Pressure Liquid; Chymotrypsin; Cysteine; DNA-Cytosine Methylases; Electrophoresis, Polyacrylamide Gel; Hydrolysis; Methylation; Molecular Sequence Data; Peptide Mapping; Photochemistry; S-Adenosylmethionine; Trypsin

1991
Identification of the structural gene for glucose-6-phosphate dehydrogenase in yeast. Inactivation leads to a nutritional requirement for organic sulfur.
    The EMBO journal, 1991, Volume: 10, Issue:3

    Topics: Amino Acid Sequence; Base Sequence; Cloning, Molecular; Cysteine; Escherichia coli; Gene Expression Regulation, Fungal; Genes, Fungal; Genotype; Glucosephosphate Dehydrogenase; Glutathione; Homocysteine; Humans; Kinetics; Methionine; Molecular Sequence Data; Mutagenesis; Phenotype; Restriction Mapping; S-Adenosylmethionine; Saccharomyces cerevisiae; Sequence Homology, Nucleic Acid; Transcription, Genetic

1991
Alkylation of an active-site cysteinyl residue during substrate-dependent inactivation of Escherichia coli S-adenosylmethionine decarboxylase.
    Biochemistry, 1991, Apr-23, Volume: 30, Issue:16

    Topics: Adenosylmethionine Decarboxylase; Alkylation; Amino Acid Sequence; Binding Sites; Carbon Radioisotopes; Cysteine; Escherichia coli; Kinetics; Molecular Sequence Data; Peptide Fragments; S-Adenosylmethionine; Schiff Bases; Spectrometry, Mass, Fast Atom Bombardment; Trypsin

1991
The gamma subunit of brain G-proteins is methyl esterified at a C-terminal cysteine.
    FEBS letters, 1990, Jan-29, Volume: 260, Issue:2

    Topics: Animals; Brain Chemistry; Carboxylic Acids; Cattle; Cell Membrane; Cysteine; Esters; GTP-Binding Proteins; Hydrolysis; Membrane Lipids; Methylation; Protein Binding; S-Adenosylmethionine

1990
High-molecular-weight forms of aminoacyl-tRNA synthetases and tRNA modification enzymes in Escherichia coli.
    Journal of bacteriology, 1990, Volume: 172, Issue:4

    Topics: Amino Acyl-tRNA Synthetases; Carbon Radioisotopes; Chromatography, Gel; Chromatography, Ion Exchange; Cysteine; Escherichia coli; Isoleucine; Methyltransferases; Molecular Weight; S-Adenosylmethionine; Sulfur Radioisotopes; Sulfurtransferases; Tritium

1990
Hepatic content of S-adenosylmethionine, S-adenosylhomocysteine and glutathione in rats receiving treatments modulating methyl donor availability.
    The Journal of nutrition, 1989, Volume: 119, Issue:10

    Topics: Animals; Biomarkers; Choline Deficiency; Cysteine; Diet; Fatty Liver; Folic Acid Deficiency; Glutathione; Homocysteine; Lipids; Liver; Male; Methionine; Methylation; Niacinamide; Rats; Rats, Inbred Strains; S-Adenosylhomocysteine; S-Adenosylmethionine

1989
Down-regulation of rat liver beta-adrenergic receptors by cysteine.
    Life sciences, 1986, Oct-27, Volume: 39, Issue:17

    Topics: Animals; Cysteine; Diet; Liver; Methionine; Methionine Adenosyltransferase; Myocardium; Rats; Rats, Inbred Strains; Receptors, Adrenergic, beta; S-Adenosylmethionine

1986
Stimulation of S-adenosylmethionine synthetase in human lymphocytes by streptococcal M protein.
    Journal of immunology (Baltimore, Md. : 1950), 1987, Jul-01, Volume: 139, Issue:1

    Topics: Antigens, Bacterial; Bacterial Outer Membrane Proteins; Bacterial Proteins; Carrier Proteins; Cells, Cultured; Cysteine; Humans; Lymphocyte Activation; Lymphocytes; Methionine Adenosyltransferase; Phytohemagglutinins; S-Adenosylmethionine; Streptococcus pyogenes; Time Factors; Transferases

1987
Growth support and toxicity of homocysteine and its effects on methionine metabolism in non-transformed and chemically transformed C3H/10T1/2 cells.
    Carcinogenesis, 1988, Volume: 9, Issue:1

    Topics: Animals; Cell Division; Cell Line; Cysteine; Dose-Response Relationship, Drug; Glutathione; Homocysteine; Homocystine; Methionine; Mice; Mice, Inbred C3H; S-Adenosylhomocysteine; S-Adenosylmethionine; Tumor Cells, Cultured

1988
Inhibition of human liver catechol-O-methyltransferase by flavonoids.
    Naunyn-Schmiedeberg's archives of pharmacology, 1973, Volume: 276, Issue:2

    Topics: Carbon Isotopes; Catechol O-Methyltransferase Inhibitors; Chemical Phenomena; Chemistry; Cysteine; Flavonoids; Humans; Hydrogen-Ion Concentration; Kinetics; Liver; Methyltransferases; Norepinephrine; Rutin; S-Adenosylmethionine; Structure-Activity Relationship

1973
In vivo synthesis of sulfur containing amino acids in Candida albicans.
    Canadian journal of microbiology, 1973, Volume: 19, Issue:2

    Topics: Agar; Candida albicans; Cystathionine; Cysteine; Homocystine; Methionine; S-Adenosylmethionine; Sulfides; Zea mays

1973
Deficiency in methionine adenosyltransferase resulting in limited repressibility of methionine biosynthetic enzymes in Aspergillus nidulans.
    Molecular & general genetics : MGG, 1973, Nov-22, Volume: 126, Issue:4

    Topics: Aspergillus nidulans; Cysteine; Enzyme Repression; Escherichia coli; Membrane Transport Proteins; Methionine; Molecular Biology; Mutation; Oxidoreductases; S-Adenosylmethionine; Saccharomyces cerevisiae; Sulfates; Sulfites; Time Factors; Transferases

1973
Regulation of S-amino acids biosynthesis in Aspergillus nidulans. Role of cysteine and-or homocysteine as regulatory effectors.
    Molecular & general genetics : MGG, 1974, Volume: 132, Issue:4

    Topics: Acetylation; Amino Acids; Aspergillus nidulans; Carboxy-Lyases; Cysteine; Genetics, Microbial; Homocysteine; Hydro-Lyases; Lyases; Molecular Biology; Mutation; S-Adenosylmethionine

1974
The synthesis of taurine from sulfate. V. Regulatory modifiers of the chick liver enzyme system.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1973, Volume: 144, Issue:2

    Topics: Adenosine Monophosphate; Alanine; Allosteric Regulation; Animals; Chickens; Cysteine; Ethionine; Homocysteine; Liver; Methionine; Organophosphorus Compounds; S-Adenosylmethionine; Serine; Sulfinic Acids; Sulfonic Acids; Sulfur Radioisotopes; Sulfuric Acids; Sulfurtransferases; Taurine

1973
Enzymatic studies on the metabolism of the tetrahydrofurfuryl mercaptan moiety of thiamine tetrahydrofurfuryl disulfide. I. Microsomal S-transmethylase.
    Journal of biochemistry, 1973, Volume: 74, Issue:4

    Topics: Animals; Ascorbic Acid; Benzenesulfonates; Carbon Radioisotopes; Chlorides; Chloromercuribenzoates; Chromatography; Cysteine; Disulfides; Furans; Glutathione; Intestine, Small; Kidney; Liver; Male; Mercury; Methionine; Methylation; Methyltransferases; Microsomes; Organometallic Compounds; Rats; S-Adenosylmethionine; Spectrophotometry, Infrared; Sulfhydryl Compounds; Thiamine; Tritium

1973
Methionine metabolism in mammals: synthesis of S-adenosylhomocysteine in rat tissues.
    Archives of biochemistry and biophysics, 1973, Volume: 159, Issue:1

    Topics: Adenosine; Animals; Carbon Radioisotopes; Chromatography, Ion Exchange; Chromatography, Paper; Cysteine; Dithiothreitol; Glucagon; Glutathione; Growth Hormone; Homocysteine; Hydrocortisone; Isotope Labeling; Liver; Male; Methionine; Organ Specificity; Rats; S-Adenosylmethionine; Thyroxine; Tritium

1973
Purification and properties of a catechol-o-methyltransferase of human liver.
    European journal of biochemistry, 1971, Aug-25, Volume: 21, Issue:4

    Topics: Carbon Isotopes; Catechols; Chemical Phenomena; Chemistry; Chlorides; Chromatography; Chromatography, DEAE-Cellulose; Chromatography, Gel; Chromatography, Ion Exchange; Cysteine; Drug Stability; Edetic Acid; Electrophoresis, Disc; Enzyme Activation; Estradiol; Humans; Hydrogen-Ion Concentration; Liver; Magnesium; Methyltransferases; Microsomes, Liver; Molecular Weight; S-Adenosylmethionine; Temperature; Ultracentrifugation

1971
Interactions between estrogens and catechol amines. 3. Studies on the methylation of catechol estrogens, catechol amines and other catechols by the ctechol-O-methyltransferases of human liver.
    The Journal of clinical endocrinology and metabolism, 1972, Volume: 34, Issue:4

    Topics: Adult; Carbon Isotopes; Catecholamines; Catechols; Chemical Phenomena; Chemistry; Chlorides; Cysteine; Dopamine; Epinephrine; Estradiol; Estriol; Estrogens; Estrone; Humans; Kinetics; Liver; Magnesium; Male; Mandelic Acids; Methylation; Methyltransferases; Norepinephrine; S-Adenosylmethionine; Time Factors

1972
Kinetic properties of a soluble catechol O-methyltransferase of human liver.
    European journal of biochemistry, 1972, Apr-24, Volume: 26, Issue:4

    Topics: Allosteric Regulation; Catechol O-Methyltransferase; Catechol O-Methyltransferase Inhibitors; Chromatography, Paper; Cysteine; Drug Interactions; Estriol; Humans; Hydrogen-Ion Concentration; Hydroxysteroids; Isomerism; Kinetics; Liver; Magnesium; Methyl Ethers; Methylation; Methyltransferases; S-Adenosylmethionine; Spectrum Analysis; Temperature

1972
Pancreas acinar cell differentiation. V. Significance of methyl groups in morphologic and enzymatic development.
    Experimental cell research, 1972, Volume: 73, Issue:1

    Topics: Amylases; Animals; Choline; Chymotrypsin; Culture Media; Cysteine; Cystine; Lipase; Methionine; Methylation; Microscopy, Electron; Organ Culture Techniques; Pancreas; Rats; RNA, Transfer; S-Adenosylmethionine

1972
Biosynthesis of Se-methylselenocysteine and S-methylcysteine in Astragalus bisculcatus. Origin of the selenomethyl and the thiomethyl groups.
    Biochimica et biophysica acta, 1972, Jun-26, Volume: 273, Issue:1

    Topics: Carbon Isotopes; Chromatography, Paper; Cystathionine; Cysteine; Methionine; Methylation; Plants; Radioisotopes; S-Adenosylmethionine; Selenium

1972
Oxidative deamination of sulfur amino acids by bacterial and snake venom L-amino acid oxidase.
    Archives of biochemistry and biophysics, 1971, Volume: 146, Issue:1

    Topics: Adenosine; Alanine; Amino Acid Oxidoreductases; Animals; Catalase; Cattle; Chromatography, Thin Layer; Cysteine; Cystine; Homocysteine; Homocystine; Hydrogen-Ion Concentration; Kinetics; Liver; Methionine; Models, Biological; Models, Structural; Oxygen Consumption; Proteus; S-Adenosylmethionine; Snakes; Species Specificity; Sulfides; Sulfur; Venoms

1971
Mutation of Saccharomyces cerevisiae preventing uptake of S-adenosylmethionine.
    Journal of bacteriology, 1971, Volume: 106, Issue:2

    Topics: Adenine; Carbon Isotopes; Colorimetry; Crosses, Genetic; Culture Media; Cysteine; Genetics, Microbial; Homocysteine; Methionine; Mutation; Nucleosides; S-Adenosylmethionine; Saccharomyces; Serine; Threonine

1971
Methionine metabolism in mammals: concentration of metabolites in rat tissues.
    The Journal of nutrition, 1982, Volume: 112, Issue:5

    Topics: Amino Acids, Sulfur; Animals; Cysteine; Cystine; Dietary Proteins; Homeostasis; Homocysteine; Male; Methionine; Rats; Rats, Inbred Strains; S-Adenosylhomocysteine; S-Adenosylmethionine; Sulfhydryl Compounds; Tissue Distribution

1982
Regulatory properties of O-acetyl-L-serine sulfhydrylase of Cephalosporium acremonium: evidence of an isoenzyme and its importance in cephalosporin C biosynthesis.
    Antimicrobial agents and chemotherapy, 1980, Volume: 18, Issue:1

    Topics: Acremonium; Cephalosporins; Chromatography, Gel; Cysteine; Cysteine Synthase; Isoenzymes; Lyases; Methionine; Mutation; S-Adenosylmethionine; Time Factors

1980
Feedback inhibition by methionine and S-adenosylmethionine, and desensitization of homoserine O-acetyltransferase in Brevibacterium flavum.
    Journal of biochemistry, 1981, Volume: 89, Issue:5

    Topics: Acetyltransferases; Brevibacterium; Cysteine; Dithiothreitol; Dose-Response Relationship, Drug; Feedback; Homoserine; Hydrogen-Ion Concentration; Hydroxymercuribenzoates; Methionine; S-Adenosylmethionine

1981
Self-methylation of the M.BspRI methyltransferase.
    Gene, 1995, May-19, Volume: 157, Issue:1-2

    Topics: Amino Acid Sequence; Cysteine; DNA-Cytosine Methylases; Methylation; Methyltransferases; S-Adenosylmethionine; Substrate Specificity

1995
Function of Pro-185 in the ProCys of conserved motif IV in the EcoRII [cytosine-C5]-DNA methyltransferase.
    FEBS letters, 1995, Aug-14, Volume: 370, Issue:1-2

    Topics: Amino Acid Sequence; Binding Sites; Cloning, Molecular; Conserved Sequence; Cysteine; DNA; DNA-Cytosine Methylases; Escherichia coli; Kinetics; Molecular Sequence Data; Mutagenesis, Site-Directed; Proline; Recombinant Proteins; S-Adenosylmethionine; Substrate Specificity

1995
Observation of a second substrate radical intermediate in the reaction of lysine 2,3-aminomutase: a radical centered on the beta-carbon of the alternative substrate, 4-thia-L-lysine.
    Biochemistry, 1995, Aug-22, Volume: 34, Issue:33

    Topics: Amino Acid Isomerases; Clostridium; Cysteine; Deuterium; Electrochemistry; Electron Spin Resonance Spectroscopy; Intramolecular Transferases; Kinetics; S-Adenosylmethionine; Substrate Specificity

1995
Stimulatory factors for enzymatic biotin synthesis from dethiobiotin in cell-free extracts of Escherichia coli.
    Bioscience, biotechnology, and biochemistry, 1995, Volume: 59, Issue:5

    Topics: Bacillus; Biotin; Cell Extracts; Cysteine; Escherichia coli; Flavin-Adenine Dinucleotide; Immunosuppressive Agents; NAD; NADP; S-Adenosylmethionine

1995
Transmembrane signalling and the aspartate receptor.
    Structure (London, England : 1993), 1994, Sep-15, Volume: 2, Issue:9

    Topics: Amino Acid Sequence; Aspartic Acid; Bacterial Physiological Phenomena; Binding Sites; Cell Membrane; Chemotaxis; Computer Graphics; Cross-Linking Reagents; Cysteine; Macromolecular Substances; Models, Molecular; Mutagenesis, Site-Directed; Protein Structure, Secondary; Receptors, Amino Acid; S-Adenosylmethionine; Signal Transduction; Software

1994
Geranylgeranylated Rab proteins terminating in Cys-Ala-Cys, but not Cys-Cys, are carboxyl-methylated by bovine brain membranes in vitro.
    Proceedings of the National Academy of Sciences of the United States of America, 1994, Oct-25, Volume: 91, Issue:22

    Topics: Amino Acid Sequence; Animals; Base Sequence; Cattle; Cerebellum; Cysteine; Diterpenes; DNA Primers; GTP-Binding Proteins; Humans; Intracellular Membranes; Kinetics; Methylation; Microsomes; Molecular Sequence Data; Nerve Tissue Proteins; Polymerase Chain Reaction; Protein Prenylation; rab1 GTP-Binding Proteins; rab3 GTP-Binding Proteins; Recombinant Proteins; S-Adenosylmethionine; Structure-Activity Relationship; Tritium

1994
On the mechanism of biotin synthase of Bacillus sphaericus.
    Comptes rendus de l'Academie des sciences. Serie III, Sciences de la vie, 1994, Volume: 317, Issue:6

    Topics: Bacillus; Biotin; Cysteine; S-Adenosylmethionine; Sulfurtransferases

1994
Mass spectrometric analysis of human soluble catechol O-methyltransferase expressed in Escherichia coli. Identification of a product of ribosomal frameshifting and of reactive cysteines involved in S-adenosyl-L-methionine binding.
    European journal of biochemistry, 1994, Jun-01, Volume: 222, Issue:2

    Topics: Amino Acid Sequence; Base Sequence; Binding Sites; Catechol O-Methyltransferase; Cloning, Molecular; Codon; Cysteine; Escherichia coli; Fluoresceins; Frameshift Mutation; Humans; Kinetics; Mass Spectrometry; Molecular Sequence Data; Peptide Fragments; Plasmids; Proline; Recombinant Proteins; Restriction Mapping; Ribosomes; S-Adenosylmethionine; Trypsin

1994
Self-methylation of BspRI DNA-methyltransferase.
    Nucleic acids research, 1994, Aug-11, Volume: 22, Issue:15

    Topics: Amino Acid Sequence; Binding, Competitive; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Cysteine; DNA; DNA-Cytosine Methylases; Escherichia coli; Methylation; Molecular Sequence Data; Protein Conformation; S-Adenosylhomocysteine; S-Adenosylmethionine; Sulfhydryl Reagents; Tritium

1994
Comparison of sulfur amino acid utilization for GSH synthesis between HepG2 cells and cultured rat hepatocytes.
    Biochemical pharmacology, 1994, Mar-02, Volume: 47, Issue:5

    Topics: Adenosine Triphosphate; Amino Acids, Sulfur; Animals; Cell Count; Cysteine; Cystine; Glutathione; Hepatoblastoma; Humans; Liver; Liver Neoplasms; Male; Methionine; Rats; Rats, Sprague-Dawley; S-Adenosylmethionine; Tumor Cells, Cultured

1994
Reconstitution and characterization of the polynuclear iron-sulfur cluster in pyruvate formate-lyase-activating enzyme. Molecular properties of the holoenzyme form.
    The Journal of biological chemistry, 1998, Feb-27, Volume: 273, Issue:9

    Topics: Acetyltransferases; Amino Acid Sequence; Apoproteins; Conserved Sequence; Cysteine; Electron Spin Resonance Spectroscopy; Enzyme Activation; Enzymes; Escherichia coli; Iron; Iron-Sulfur Proteins; Ligands; Molecular Sequence Data; Mutagenesis, Site-Directed; Recombinant Proteins; S-Adenosylhomocysteine; S-Adenosylmethionine; Spectrophotometry; Sulfides

1998
Identification of the essential cysteinyl residue located in the active site of human phenylethanolamine N-methyltransferase.
    Biochemical and biophysical research communications, 1998, Aug-19, Volume: 249, Issue:2

    Topics: Amino Acid Sequence; Animals; Binding Sites; Cysteine; Escherichia coli; Gene Expression; Humans; Kinetics; Molecular Sequence Data; Mutagenesis, Site-Directed; Norepinephrine; Phenylethanolamine N-Methyltransferase; Polymerase Chain Reaction; S-Adenosylmethionine; Sequence Homology; Serine; Substrate Specificity

1998
Effect of betaine administration on metabolism of hepatic glutathione in rats.
    Archives of pharmacal research, 1998, Volume: 21, Issue:6

    Topics: Animals; Betaine; Cysteine; Female; Glutathione; Injections, Intraperitoneal; Liver; Rats; S-Adenosylhomocysteine; S-Adenosylmethionine

1998
Role of cysteine-82 in the catalytic mechanism of human S-adenosylmethionine decarboxylase.
    Biochemistry, 1999, Feb-23, Volume: 38, Issue:8

    Topics: Adenosylmethionine Decarboxylase; Catalysis; Cysteine; Enzyme Activation; Enzyme Inhibitors; Histidine; Humans; Hydrogen-Ion Concentration; Iodoacetic Acid; Kinetics; Mutagenesis, Site-Directed; Recombinant Fusion Proteins; S-Adenosylmethionine; Substrate Specificity

1999
Cysteine is essential for transcriptional regulation of the sulfur assimilation genes in Saccharomyces cerevisiae.
    Molecular & general genetics : MGG, 2000, Volume: 263, Issue:3

    Topics: Blotting, Northern; Carbon-Oxygen Lyases; Cysteine; Cysteine Synthase; Gene Deletion; Gene Expression Regulation, Fungal; Models, Genetic; Multienzyme Complexes; Mutagenesis; Open Reading Frames; Plasmids; S-Adenosylmethionine; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Sulfur; Transcription, Genetic

2000
A substrate switch: a new mode of regulation in the methionine metabolic pathway.
    Journal of theoretical biology, 2000, Jun-21, Volume: 204, Issue:4

    Topics: Animals; Cysteine; Glycine N-Methyltransferase; Isoenzymes; Liver; Methionine; Methionine Adenosyltransferase; Methyltransferases; Models, Biological; S-Adenosylmethionine

2000
m5C RNA and m5C DNA methyl transferases use different cysteine residues as catalysts.
    Proceedings of the National Academy of Sciences of the United States of America, 2000, Jul-18, Volume: 97, Issue:15

    Topics: Amino Acid Sequence; Catalysis; Cysteine; Dipeptides; DNA Modification Methylases; Methyltransferases; Molecular Sequence Data; Proline; RNA, Ribosomal, 16S; S-Adenosylmethionine

2000
Polyamines and thiols in the cytoprotective effect of L-cysteine and L-methionine on carbon tetrachloride-induced hepatotoxicity.
    Amino acids, 2000, Volume: 18, Issue:4

    Topics: Animals; Carbon Tetrachloride; Cells, Cultured; Cysteine; Cytoprotection; Dose-Response Relationship, Drug; Glutathione; Glutathione Transferase; Hepatocytes; L-Lactate Dehydrogenase; Male; Maleates; Methionine; Mitoguazone; Polyamines; Rats; Rats, Sprague-Dawley; S-Adenosylmethionine; Sulfhydryl Compounds

2000
Farnesyl-L-cysteine analogs block SAM-induced Parkinson's disease-like symptoms in rats.
    Pharmacology, biochemistry, and behavior, 2000, Volume: 66, Issue:4

    Topics: Amphetamine; Animals; Central Nervous System Stimulants; Chromatography, Gel; Cysteine; Freeze Drying; Male; Methylation; Motor Activity; Nerve Tissue Proteins; Oxidopamine; Parkinson Disease, Secondary; Rats; Rats, Sprague-Dawley; S-Adenosylmethionine; Stereotyped Behavior; Sympathectomy, Chemical; Tremor

2000
The role of cysteine residues in tellurite resistance mediated by the TehAB determinant.
    Biochemical and biophysical research communications, 2000, Oct-22, Volume: 277, Issue:2

    Topics: Alanine; Alkylating Agents; Bacterial Proteins; Binding Sites; Cysteine; Dithionitrobenzoic Acid; Drug Resistance; Electrophoresis, Polyacrylamide Gel; Enzyme Inhibitors; Escherichia coli; Escherichia coli Proteins; Ethylmaleimide; Iodoacetamide; Iodoacetates; Ligands; Microbial Sensitivity Tests; Mutagenesis, Site-Directed; Phenotype; Plasmids; Protein Binding; Protein Conformation; Protein Denaturation; S-Adenosylmethionine; Sulfhydryl Reagents; Tellurium; Up-Regulation

2000
Reviving a dead enzyme: cytosine deaminations promoted by an inactive DNA methyltransferase and an S-adenosylmethionine analogue.
    Biochemistry, 2000, Nov-28, Volume: 39, Issue:47

    Topics: Adenosine; Alanine; Cysteine; Cytosine; Deamination; DNA (Cytosine-5-)-Methyltransferases; DNA-Cytosine Methylases; Enzyme Inhibitors; Escherichia coli; Mutagenesis, Site-Directed; S-Adenosylmethionine; Serine; Uracil

2000
Occurrence of transsulfuration in synthesis of L-homocysteine in an extremely thermophilic bacterium, Thermus thermophilus HB8.
    Journal of bacteriology, 2001, Volume: 183, Issue:6

    Topics: Culture Media; Cystathionine; Cystathionine gamma-Lyase; Cysteine; Cysteine Synthase; Gene Expression Regulation, Bacterial; Homocysteine; Lyases; Methionine; S-Adenosylmethionine; Sulfur; Temperature; Thermus thermophilus

2001
Determination of allicin, S-allylcysteine and volatile metabolites of garlic in breath, plasma or simulated gastric fluids.
    The Journal of nutrition, 2001, Volume: 131, Issue:3s

    Topics: Allyl Compounds; Breath Tests; Chromatography, Gas; Chromatography, High Pressure Liquid; Cysteine; Disulfides; Garlic; Gas Chromatography-Mass Spectrometry; Gastrointestinal Contents; Glutathione; Humans; Plant Extracts; Plants, Medicinal; S-Adenosylmethionine; Sulfides; Sulfinic Acids

2001
Activation of class III ribonucleotide reductase by thioredoxin.
    The Journal of biological chemistry, 2001, Mar-30, Volume: 276, Issue:13

    Topics: Animals; Arabidopsis; Chlamydomonas reinhardtii; Cysteine; Disulfides; Dithiothreitol; Dose-Response Relationship, Drug; Enzyme Activation; Escherichia coli; Free Radicals; NADP; Protein Structure, Tertiary; Ribonucleotide Reductases; S-Adenosylmethionine; Spectrophotometry; Thioredoxins; Time Factors; Ultraviolet Rays

2001
Homocysteine metabolism in children with Down syndrome: in vitro modulation.
    American journal of human genetics, 2001, Volume: 69, Issue:1

    Topics: Adenosine; Case-Control Studies; Child; Chromatography, High Pressure Liquid; Cystathionine; Cystathionine beta-Synthase; Cysteine; DNA Methylation; Down Syndrome; Glutathione; Homocysteine; Humans; Leucovorin; Lymphocytes; Methionine; Oxidative Stress; S-Adenosylhomocysteine; S-Adenosylmethionine; Sarcosine; Superoxide Dismutase; Thymidine; Vitamin B 12

2001
COMT genotype, micronutrients in the folate metabolic pathway and breast cancer risk.
    Carcinogenesis, 2001, Volume: 22, Issue:10

    Topics: Breast Neoplasms; Case-Control Studies; Catechol O-Methyltransferase; Cysteine; Estrogens, Catechol; Female; Folic Acid; Genotype; Homocysteine; Humans; Methylation; Micronutrients; Middle Aged; Polymerase Chain Reaction; Polymorphism, Restriction Fragment Length; Pyridoxal Phosphate; Risk Factors; S-Adenosylmethionine; Vitamin B 12

2001
Reductive cleavage of S-adenosylmethionine by biotin synthase from Escherichia coli.
    The Journal of biological chemistry, 2002, Apr-19, Volume: 277, Issue:16

    Topics: Biotin; Cysteine; Electron Spin Resonance Spectroscopy; Escherichia coli; Kinetics; Methionine; Models, Chemical; Mutation; S-Adenosylmethionine; Spectroscopy, Mossbauer; Sulfurtransferases; Time Factors

2002
Brain hydrogen sulfide is severely decreased in Alzheimer's disease.
    Biochemical and biophysical research communications, 2002, May-24, Volume: 293, Issue:5

    Topics: Alzheimer Disease; Amino Acids; Blotting, Western; Brain; Cysteine; Dose-Response Relationship, Drug; Homocysteine; Humans; Hydrogen Sulfide; S-Adenosylmethionine

2002
The production of hydrogen sulfide is regulated by testosterone and S-adenosyl-L-methionine in mouse brain.
    Journal of neurochemistry, 2002, Volume: 83, Issue:1

    Topics: Age Factors; Aging; Animals; Brain; Chromatography, High Pressure Liquid; Cystathionine beta-Synthase; Cysteine; Female; Hydrogen Sulfide; Male; Mice; Mice, Inbred BALB C; S-Adenosylmethionine; Sex Factors; Testosterone

2002
S-homoadenosyl-L-cysteine and S-homoadenosyl-L-homocysteine. Synthesis and binding studies of hon-hydrolyzed substrate analogues with S-adenosyl-L-homocysteine hydrolase.
    The Journal of organic chemistry, 2002, Nov-15, Volume: 67, Issue:23

    Topics: Adenosylhomocysteinase; Cysteine; Enzyme Inhibitors; Homocysteine; Humans; Hydrolases; Kinetics; Placenta; Protein Binding; S-Adenosylmethionine

2002
Leishmania donovani methionine adenosyltransferase. Role of cysteine residues in the recombinant enzyme.
    European journal of biochemistry, 2003, Volume: 270, Issue:1

    Topics: Amino Acid Substitution; Animals; Cloning, Molecular; Cysteine; Feedback, Physiological; Hydrolysis; Leishmania donovani; Methionine Adenosyltransferase; Molecular Sequence Data; Mutation; Polyphosphates; Protein Folding; Recombinant Proteins; S-Adenosylmethionine

2003
Cobalamin deficiency with and without neurologic abnormalities: differences in homocysteine and methionine metabolism.
    Blood, 2003, Apr-15, Volume: 101, Issue:8

    Topics: Anemia; Anemia, Pernicious; Cysteine; Dipeptides; Folic Acid; Glutathione; Homocysteine; Humans; Memory Disorders; Methionine; Movement Disorders; Nervous System Diseases; Retrospective Studies; S-Adenosylmethionine; Sensation Disorders; Vitamin B 12; Vitamin B 12 Deficiency

2003
Isoprenylcysteine carboxyl methyltransferase activity modulates endothelial cell apoptosis.
    Molecular biology of the cell, 2003, Volume: 14, Issue:3

    Topics: Acetylcysteine; Adenosine; Animals; Apoptosis; Cattle; Cells, Cultured; Cysteine; Diterpenes; Endothelium, Vascular; Enzyme Inhibitors; Mitogen-Activated Protein Kinases; Protein Methyltransferases; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Pulmonary Artery; ras Proteins; S-Adenosylhomocysteine; S-Adenosylmethionine; Signal Transduction; Ultraviolet Rays

2003
Conformational dynamics of the active site loop of S-adenosylmethionine synthetase illuminated by site-directed spin labeling.
    Archives of biochemistry and biophysics, 2003, Jul-15, Volume: 415, Issue:2

    Topics: Cysteine; Electron Spin Resonance Spectroscopy; Enzyme Activation; Kinetics; Models, Molecular; Motion; Mutagenesis, Site-Directed; Protein Conformation; Protein Structure, Secondary; Recombinant Proteins; S-Adenosylmethionine; Spin Labels

2003
Regulation of S-adenosylmethionine levels in Saccharomyces cerevisiae.
    The Journal of biological chemistry, 2003, Oct-31, Volume: 278, Issue:44

    Topics: Cell Division; Cysteine; Formates; Gene Deletion; Gene Expression Regulation, Fungal; Genotype; Glycine; Homocysteine; Microscopy, Fluorescence; Models, Biological; Mutation; S-Adenosylmethionine; Saccharomyces cerevisiae; Sulfur; Time Factors; Vacuoles

2003
Cigarette smoke extract increases S-adenosylmethionine and cystathionine in human lung epithelial-like (A549) cells.
    Chemico-biological interactions, 2004, Jan-15, Volume: 147, Issue:1

    Topics: Amino Acids, Sulfur; Carcinoma; Cell Line, Tumor; Cell Survival; Cystathionine; Cysteine; DNA; Glutathione; Humans; Lung Neoplasms; Methionine; Nicotiana; S-Adenosylhomocysteine; S-Adenosylmethionine; Smoke; Time Factors

2004
Post-translational formylglycine modification of bacterial sulfatases by the radical S-adenosylmethionine protein AtsB.
    The Journal of biological chemistry, 2004, Apr-09, Volume: 279, Issue:15

    Topics: Alanine; Amino Acid Motifs; Bacteria; Binding Sites; Chelating Agents; Cysteine; Dose-Response Relationship, Drug; Escherichia coli; Glutathione Transferase; Hydrogen; Iron-Sulfur Proteins; Klebsiella pneumoniae; Models, Chemical; Mutagenesis, Site-Directed; Oxygen; Peptides; Protein Processing, Post-Translational; S-Adenosylmethionine; Sulfatases; Temperature; Time Factors

2004
Thiamine biosynthesis in Escherichia coli: in vitro reconstitution of the thiazole synthase activity.
    The Journal of biological chemistry, 2004, Apr-23, Volume: 279, Issue:17

    Topics: Adenosine; Bacterial Proteins; Carbon-Sulfur Lyases; Carrier Proteins; Cell-Free System; Chromatography, High Pressure Liquid; Culture Media; Cysteine; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Escherichia coli; Escherichia coli Proteins; Ligases; Models, Chemical; NADP; Nucleotidyltransferases; Plasmids; S-Adenosylmethionine; Sulfurtransferases; Thiamine; Thiazoles; Time Factors; Tyrosine

2004
Insight into the polar reactivity of the onium chalcogen analogues of S-adenosyl-L-methionine.
    Biochemistry, 2004, Oct-26, Volume: 43, Issue:42

    Topics: Alkylating Agents; Biotransformation; Chalcogens; Cysteine; Escherichia coli; Humans; Methionine; Methionine Adenosyltransferase; Nuclear Magnetic Resonance, Biomolecular; Organoselenium Compounds; Protons; S-Adenosylmethionine; Selenocysteine; Selenomethionine; Stereoisomerism; Substrate Specificity; Sulfonium Compounds; Tellurium

2004
Metabolic biomarkers of increased oxidative stress and impaired methylation capacity in children with autism.
    The American journal of clinical nutrition, 2004, Volume: 80, Issue:6

    Topics: Adenosine; Autistic Disorder; Betaine; Biomarkers; Case-Control Studies; Child; Chromatography, High Pressure Liquid; Cystathionine; Cysteine; Female; Glutathione; Homocysteine; Humans; Leucovorin; Male; Methionine; Methylation; Oxidative Stress; S-Adenosylhomocysteine; S-Adenosylmethionine; Vitamin B 12

2004
Homocysteine alterations in experimental cholestasis and its subsequent cirrhosis.
    Life sciences, 2005, Apr-08, Volume: 76, Issue:21

    Topics: Analysis of Variance; Animals; Bile Ducts; Cholestasis; Cysteine; Glutathione; Homocysteine; Ligation; Liver; Liver Cirrhosis, Biliary; Male; Methionine; NG-Nitroarginine Methyl Ester; Nitric Oxide; Rats; Rats, Sprague-Dawley; S-Adenosylhomocysteine; S-Adenosylmethionine; Time Factors

2005
Disturbed homocysteine and methionine cycle intermediates S-adenosylhomocysteine and S-adenosylmethionine are related to degree of renal insufficiency in type 2 diabetes.
    Clinical chemistry, 2005, Volume: 51, Issue:5

    Topics: Aged; Cystathionine; Cysteine; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Female; Folic Acid; Homocysteine; Humans; Kidney; Kidney Failure, Chronic; Male; Methionine; Methylmalonic Acid; Middle Aged; S-Adenosylhomocysteine; S-Adenosylmethionine; Transcobalamins; Vitamin B 12; Vitamin B 6

2005
Effect of betaine supplementation on changes in hepatic metabolism of sulfur-containing amino acids and experimental cholestasis induced by alpha-naphthylisothiocyanate.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2005, Volume: 43, Issue:5

    Topics: 1-Naphthylisothiocyanate; Alanine Transaminase; Alkaline Phosphatase; Amino Acids, Sulfur; Analysis of Variance; Animals; Aspartate Aminotransferases; Betaine; Bilirubin; Cholestasis; Cysteine; Dietary Supplements; Glutathione; Kinetics; Liver; Male; Mice; Mice, Inbred ICR; S-Adenosylhomocysteine; S-Adenosylmethionine

2005
Effects of betaine supplementation on hepatic metabolism of sulfur-containing amino acids in mice.
    Journal of hepatology, 2005, Volume: 42, Issue:6

    Topics: Amino Acids, Sulfur; Animals; Betaine; Chemical and Drug Induced Liver Injury; Chloroform; Cysteine; Glutathione; Kidney; Lipotropic Agents; Liver; Male; Methionine; Methionine Adenosyltransferase; Mice; Mice, Inbred ICR; S-Adenosylmethionine; Solvents; Taurine

2005
Radical S-adenosylmethionine enzyme coproporphyrinogen III oxidase HemN: functional features of the [4Fe-4S] cluster and the two bound S-adenosyl-L-methionines.
    The Journal of biological chemistry, 2005, Aug-12, Volume: 280, Issue:32

    Topics: Bacterial Proteins; Binding Sites; Catalysis; Cell-Free System; Chromatography, High Pressure Liquid; Circular Dichroism; Coproporphyrinogen Oxidase; Crystallography, X-Ray; Cysteine; Electron Spin Resonance Spectroscopy; Escherichia coli; Free Radicals; Iron; Iron-Sulfur Proteins; Ligands; Models, Chemical; Models, Molecular; Mutagenesis, Site-Directed; Mutation; Oxidoreductases Acting on CH-CH Group Donors; Protein Binding; Protoporphyrinogen Oxidase; Recombinant Proteins; S-Adenosylmethionine; Spectrophotometry; Spectroscopy, Mossbauer; Structure-Activity Relationship; Substrate Specificity; Time Factors

2005
Hepatic S-adenosylmethionine after maternal alcohol exposure on offspring rats.
    Addiction biology, 2005, Volume: 10, Issue:2

    Topics: Animals; Animals, Newborn; Cysteine; DNA Methylation; Drug Administration Schedule; Ethanol; Female; Homocysteine; Lactation; Liver; Male; Maternal Behavior; Nutritional Status; Pregnancy; Pregnancy, Animal; Random Allocation; Rats; Rats, Wistar; S-Adenosylmethionine

2005
The Elongator subunit Elp3 contains a Fe4S4 cluster and binds S-adenosylmethionine.
    Molecular microbiology, 2006, Volume: 59, Issue:3

    Topics: Amino Acid Sequence; Archaeal Proteins; Cysteine; Iron; Iron-Sulfur Proteins; Methanococcales; Molecular Sequence Data; Mutagenesis, Site-Directed; Protein Structure, Tertiary; Protein Subunits; S-Adenosylmethionine; Sulfides

2006
Determinants of the ubiquitin-mediated degradation of the Met4 transcription factor.
    The Journal of biological chemistry, 2006, Apr-28, Volume: 281, Issue:17

    Topics: Basic Helix-Loop-Helix Leucine Zipper Transcription Factors; Basic-Leucine Zipper Transcription Factors; Cell Nucleus; Chromosomal Instability; Cysteine; F-Box Proteins; Gene Expression Regulation, Fungal; Kinetochores; Methionine; Proteasome Endopeptidase Complex; Recombinant Fusion Proteins; Repressor Proteins; S-Adenosylmethionine; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Sulfur; Transcription, Genetic; Ubiquitin; Ubiquitin-Protein Ligase Complexes

2006
The 5th workshop on the assessment of adequate intake of dietary amino acids: general discussion 1.
    The Journal of nutrition, 2006, Volume: 136, Issue:6 Suppl

    Topics: Amino Acids; Animals; Creatine; Cysteine; Diet; Glutathione; Homocysteine; Humans; Methionine; Nutritional Requirements; S-Adenosylhomocysteine; S-Adenosylmethionine

2006
Solvent-accessible cysteines in human cystathionine beta-synthase: crucial role of cysteine 431 in S-adenosyl-L-methionine binding.
    Biochemistry, 2006, Sep-12, Volume: 45, Issue:36

    Topics: Binding Sites; Cystathionine beta-Synthase; Cysteine; Enzyme Activation; Humans; Mutagenesis, Site-Directed; S-Adenosylmethionine; Sequence Analysis, Protein; Solvents

2006
Nitric oxide modulates glutathione synthesis during endotoxemia.
    Free radical biology & medicine, 2006, Dec-15, Volume: 41, Issue:12

    Topics: Animals; Body Weight; Catalase; Cysteine; Disease Models, Animal; Eating; Endotoxemia; Glutamate-Cysteine Ligase; Glutathione; Injections; Lipopolysaccharides; Liver; Male; Mice; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitrites; S-Adenosylhomocysteine; S-Adenosylmethionine; Superoxide Dismutase

2006
Cysteine supplementation decreases plasma homocysteine concentration in rats fed on a low-casein diet in rats.
    Bioscience, biotechnology, and biochemistry, 2007, Volume: 71, Issue:1

    Topics: Animal Feed; Animals; Body Weight; Caseins; Cysteine; Dietary Supplements; Homocysteine; Liver; Male; Organ Size; Rats; Rats, Wistar; S-Adenosylmethionine

2007
Overexpression of yeast S-adenosylmethionine synthetase metK in Streptomyces actuosus leads to increased production of nosiheptide.
    Applied microbiology and biotechnology, 2008, Volume: 78, Issue:6

    Topics: Cysteine; Gene Expression; Genetic Engineering; Industrial Microbiology; Methionine Adenosyltransferase; S-Adenosylmethionine; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Streptomyces; Thiazoles

2008
Anaerobic sulfatase-maturating enzymes, first dual substrate radical S-adenosylmethionine enzymes.
    The Journal of biological chemistry, 2008, Jun-27, Volume: 283, Issue:26

    Topics: Bacteroides; Binding Sites; Clostridium perfringens; Cysteine; Electron Spin Resonance Spectroscopy; Hydrogen; Iron-Sulfur Proteins; Oxidation-Reduction; Oxygen; Protein Processing, Post-Translational; S-Adenosylmethionine; Serine; Spectrum Analysis, Raman; Substrate Specificity; Sulfatases

2008
Crystal structures of human 108V and 108M catechol O-methyltransferase.
    Journal of molecular biology, 2008, Jun-27, Volume: 380, Issue:1

    Topics: Binding Sites; Catechol O-Methyltransferase; Catechols; Crystallography, X-Ray; Cysteine; Humans; Methionine; Models, Molecular; Mutant Proteins; Polymorphism, Single Nucleotide; Protein Structure, Secondary; S-Adenosylmethionine; Valine

2008
Taurine supplementation improves the utilization of sulfur-containing amino acids in rats continually administrated alcohol.
    The Journal of nutritional biochemistry, 2009, Volume: 20, Issue:2

    Topics: Alcohol Drinking; Animals; Cysteine; Ethanol; Methionine; Pyridoxal Phosphate; Rats; Rats, Sprague-Dawley; S-Adenosylhomocysteine; S-Adenosylmethionine; Taurine

2009
Methionine metabolism in an animal model of sepsis.
    Clinical chemistry and laboratory medicine, 2008, Volume: 46, Issue:10

    Topics: Animals; Cysteine; Disease Models, Animal; Glutathione; Homocysteine; Lipopolysaccharides; Male; Methionine; Oxidation-Reduction; Rats; S-Adenosylhomocysteine; S-Adenosylmethionine; Sepsis

2008
Human polycomb 2 protein is a SUMO E3 ligase and alleviates substrate-induced inhibition of cystathionine beta-synthase sumoylation.
    PloS one, 2008, Volume: 3, Issue:12

    Topics: Cystathionine beta-Synthase; Cysteine; Enzyme Activation; Homocysteine; Humans; Ligases; Models, Molecular; Polycomb-Group Proteins; Protein Processing, Post-Translational; Repressor Proteins; S-Adenosylmethionine; Serine; SUMO-1 Protein; Ubiquitin-Protein Ligases

2008
Hepatic cystathionine beta-synthase activity does not increase in response to methionine supplementation in rats fed a low casein diet: association with plasma homocysteine concentrations.
    Journal of nutritional science and vitaminology, 2009, Volume: 55, Issue:2

    Topics: Animals; Betaine-Homocysteine S-Methyltransferase; Caseins; Cystathionine beta-Synthase; Cysteine; Dietary Proteins; Dietary Supplements; Dose-Response Relationship, Drug; Energy Intake; Glycine; Homocysteine; Liver; Male; Methionine; Organ Size; Rats; Rats, Wistar; RNA, Messenger; S-Adenosylhomocysteine; S-Adenosylmethionine; Serine; Weight Gain

2009
Boron deprivation decreases liver S-adenosylmethionine and spermidine and increases plasma homocysteine and cysteine in rats.
    Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS), 2009, Volume: 23, Issue:3

    Topics: Animals; Boron; Cysteine; Dinoprost; Female; Fish Oils; Homocysteine; Liver; Male; Oxidative Stress; Rats; S-Adenosylmethionine; Spermidine

2009
Alpha-lipoic acid induces elevated S-adenosylhomocysteine and depletes S-adenosylmethionine.
    Free radical biology & medicine, 2009, Oct-15, Volume: 47, Issue:8

    Topics: Animals; Antioxidants; Cysteine; Gas Chromatography-Mass Spectrometry; Liver; Male; Methylation; Rats; Rats, Sprague-Dawley; S-Adenosylhomocysteine; S-Adenosylmethionine; Thioctic Acid

2009
Tyrosine, cysteine, and S-adenosyl methionine stimulate in vitro [FeFe] hydrogenase activation.
    PloS one, 2009, Oct-26, Volume: 4, Issue:10

    Topics: Bacterial Proteins; Catalytic Domain; Cell-Free System; Chlamydomonas reinhardtii; Cysteine; Escherichia coli; Genetic Vectors; Hydrogen; Hydrogen-Ion Concentration; Hydrogenase; In Vitro Techniques; Iron; Iron-Sulfur Proteins; Models, Chemical; S-Adenosylmethionine; Tyrosine

2009
Coproporphyrin excretion and low thiol levels caused by point mutation in the Rhodobacter sphaeroides S-adenosylmethionine synthetase gene.
    Journal of bacteriology, 2010, Volume: 192, Issue:5

    Topics: Amino Acid Sequence; Amino Acid Substitution; Coproporphyrins; Cysteine; DNA Mutational Analysis; DNA, Bacterial; Genetic Complementation Test; Glutathione; Methionine Adenosyltransferase; Models, Biological; Molecular Sequence Data; Mutation, Missense; Point Mutation; Rhodobacter sphaeroides; S-Adenosylmethionine; Sequence Alignment; Sequence Analysis, DNA; Sulfhydryl Compounds

2010
Anaerobic sulfatase-maturating enzyme--a mechanistic link with glycyl radical-activating enzymes?
    The FEBS journal, 2010, Volume: 277, Issue:8

    Topics: Alanine; Anaerobiosis; Binding Sites; Catalysis; Cysteine; Electron Spin Resonance Spectroscopy; Eukaryota; Glycine; Iron-Sulfur Proteins; Oxidation-Reduction; S-Adenosylmethionine; Serine; Substrate Specificity; Sulfatases

2010
Metabolome analysis revealed increase in S-methylcysteine and phosphatidylisopropanolamine synthesis upon L-cysteine deprivation in the anaerobic protozoan parasite Entamoeba histolytica.
    The Journal of biological chemistry, 2010, Dec-10, Volume: 285, Issue:50

    Topics: Chromatography, Thin Layer; Cysteine; Cysteine Synthase; Entamoeba histolytica; Gene Expression Regulation; Glycolysis; Kinetics; Metabolomics; Oxidative Stress; Propanolamines; S-Adenosylmethionine; Serine

2010
Functional and structural evaluation of cysteine residues in the human arsenic (+3 oxidation state) methyltransferase (hAS3MT).
    Biochimie, 2011, Volume: 93, Issue:2

    Topics: Arsenites; Biocatalysis; Cysteine; Hot Temperature; Humans; Kinetics; Methyltransferases; Mutagenesis, Site-Directed; Mutation; Protein Structure, Secondary; S-Adenosylmethionine

2011
Glycine-N methyltransferase expression in HepG2 cells is involved in methyl group homeostasis by regulating transmethylation kinetics and DNA methylation.
    The Journal of nutrition, 2011, Volume: 141, Issue:5

    Topics: Carcinoma, Hepatocellular; Cysteine; Cytidine; DNA Methylation; DNA Modification Methylases; Gene Expression; Glycine N-Methyltransferase; Hep G2 Cells; Hepatocytes; Homeostasis; Homocysteine; Humans; Kinetics; Liver Neoplasms; Methionine; Methionine Adenosyltransferase; Methylation; Osmolar Concentration; S-Adenosylhomocysteine; S-Adenosylmethionine

2011
A radically different mechanism for S-adenosylmethionine-dependent methyltransferases.
    Science (New York, N.Y.), 2011, Apr-29, Volume: 332, Issue:6029

    Topics: Adenosine; Bacterial Proteins; Biocatalysis; Carbon; Chemical Phenomena; Cysteine; Escherichia coli; Escherichia coli Proteins; Hydrogen; Methylation; Methyltransferases; RNA, Bacterial; RNA, Ribosomal, 23S; S-Adenosylmethionine; Staphylococcus aureus

2011
Auto-methylation of the mouse DNA-(cytosine C5)-methyltransferase Dnmt3a at its active site cysteine residue.
    The FEBS journal, 2011, Volume: 278, Issue:12

    Topics: Amino Acid Substitution; Animals; Base Sequence; Catalytic Domain; Cysteine; DNA (Cytosine-5-)-Methyltransferases; DNA Methyltransferase 3A; Humans; In Vitro Techniques; Kinetics; Methylation; Mice; Models, Molecular; Mutagenesis, Site-Directed; Oligodeoxyribonucleotides; Recombinant Proteins; S-Adenosylhomocysteine; S-Adenosylmethionine; Substrate Specificity

2011
Structural basis for methyl transfer by a radical SAM enzyme.
    Science (New York, N.Y.), 2011, May-27, Volume: 332, Issue:6033

    Topics: Bacterial Proteins; Catalytic Domain; Crystallography, X-Ray; Cysteine; Escherichia coli; Escherichia coli Proteins; Evolution, Molecular; Hydrogen Bonding; Methylation; Methyltransferases; Models, Molecular; Oxidation-Reduction; Protein Conformation; Protein Structure, Secondary; Protein Structure, Tertiary; RNA, Bacterial; RNA, Ribosomal, 23S; S-Adenosylmethionine

2011
Biochemistry. The two faces of SAM.
    Science (New York, N.Y.), 2011, Apr-29, Volume: 332, Issue:6029

    Topics: Adenine; Adenosine; Bacterial Proteins; Biocatalysis; Catalytic Domain; Chemical Phenomena; Cysteine; Drug Resistance, Multiple, Bacterial; Escherichia coli; Escherichia coli Proteins; Methylation; Methyltransferases; RNA, Bacterial; RNA, Ribosomal, 23S; S-Adenosylmethionine; Staphylococcus aureus

2011
[Function of luxS gene in sulfurmetabolism of Streptococcus mutans].
    Zhonghua kou qiang yi xue za zhi = Zhonghua kouqiang yixue zazhi = Chinese journal of stomatology, 2011, Volume: 46, Issue:4

    Topics: Bacterial Proteins; Biofilms; Carbon-Sulfur Lyases; Culture Media; Culture Techniques; Cysteine; Gene Expression Regulation, Bacterial; Methionine; Microscopy, Confocal; Quorum Sensing; S-Adenosylhomocysteine; S-Adenosylmethionine; Streptococcus mutans; Sulfur

2011
Inhibition of betaine-homocysteine S-methyltransferase in rats causes hyperhomocysteinemia and reduces liver cystathionine β-synthase activity and methylation capacity.
    Nutrition research (New York, N.Y.), 2011, Volume: 31, Issue:7

    Topics: Animals; Betaine-Homocysteine S-Methyltransferase; Cystathionine beta-Synthase; Cysteine; Diet; Enzyme Inhibitors; Fatty Liver; Glutathione; Homeostasis; Homocysteine; Hyperhomocysteinemia; Liver; Male; Methionine; Methylation; Rats; Rats, Inbred Strains; S-Adenosylmethionine

2011
The radical SAM enzyme AlbA catalyzes thioether bond formation in subtilosin A.
    Nature chemical biology, 2012, Feb-26, Volume: 8, Issue:4

    Topics: Amino Acid Motifs; Amino Acid Sequence; Bacillus subtilis; Bacterial Proteins; Bacteriocins; Base Sequence; Binding Sites; Cysteine; Electron Spin Resonance Spectroscopy; Iron-Sulfur Proteins; Molecular Sequence Data; Mutagenesis; Operon; Peptides, Cyclic; Phenylalanine; S-Adenosylmethionine; Sulfides; Threonine

2012
Computational analysis of cysteine and methionine metabolism and its regulation in dairy starter and related bacteria.
    Journal of bacteriology, 2012, Volume: 194, Issue:13

    Topics: Bacterial Proteins; Computational Biology; Cysteine; Dairying; Gene Expression Regulation, Bacterial; Gene Expression Regulation, Enzymologic; Lactobacillales; Methionine; Methionine Adenosyltransferase; S-Adenosylmethionine; Streptococcaceae; Transcription Factors; Transcription, Genetic

2012
Is protein methylation in the human lens a result of non-enzymatic methylation by S-adenosylmethionine?
    Experimental eye research, 2012, Volume: 99

    Topics: Adolescent; Adult; Aged; Aging; beta-Crystallin A Chain; Chromatography, High Pressure Liquid; Cysteine; Histidine; Humans; Lens, Crystalline; Mass Spectrometry; Methylation; Middle Aged; Protein Methyltransferases; Protein Processing, Post-Translational; Proteomics; S-Adenosylmethionine; Tissue Donors; Young Adult

2012
Blood biomarkers of methylation in Down syndrome and metabolic simulations using a mathematical model.
    Molecular nutrition & food research, 2012, Volume: 56, Issue:10

    Topics: Adolescent; Adult; Betaine; Biomarkers; Case-Control Studies; Child; Child, Preschool; Choline; Cystathionine; Cysteine; Down Syndrome; Female; Glutathione; Humans; Infant; Male; Methionine; Methylation; Models, Theoretical; S-Adenosylhomocysteine; S-Adenosylmethionine; Sarcosine; Young Adult

2012
4-Demethylwyosine synthase from Pyrococcus abyssi is a radical-S-adenosyl-L-methionine enzyme with an additional [4Fe-4S](+2) cluster that interacts with the pyruvate co-substrate.
    The Journal of biological chemistry, 2012, Nov-30, Volume: 287, Issue:49

    Topics: Amino Acid Sequence; Archaeal Proteins; Carboxy-Lyases; Catalysis; Chromatography, High Pressure Liquid; Cloning, Molecular; Cluster Analysis; Cysteine; Electron Spin Resonance Spectroscopy; Guanosine; Iron-Sulfur Proteins; Mass Spectrometry; Models, Chemical; Molecular Sequence Data; Oxidoreductases; Pyrococcus abyssi; Pyruvic Acid; RNA, Transfer; S-Adenosylmethionine; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Sequence Homology, Amino Acid; Substrate Specificity; Ultraviolet Rays

2012
Elevation of cysteine consumption in tamoxifen-resistant MCF-7 cells.
    Biochemical pharmacology, 2013, Jan-15, Volume: 85, Issue:2

    Topics: Antineoplastic Agents, Hormonal; Breast Neoplasms; Cell Line, Tumor; Cell Survival; Cystathionine gamma-Lyase; Cysteine; Drug Resistance, Neoplasm; Enzyme Inhibitors; Female; Glutamate-Cysteine Ligase; Glutathione; Humans; Membrane Transport Modulators; Methionine; Methylation; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; S-Adenosylhomocysteine; S-Adenosylmethionine; Tamoxifen; Taurine; Up-Regulation

2013
Hepatic metabolism of sulfur amino acids in db/db mice.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2013, Volume: 53

    Topics: Amino Acids, Sulfur; Animals; Betaine-Homocysteine S-Methyltransferase; Cysteine; Cysteine Dioxygenase; Diabetes Mellitus, Experimental; Dipeptides; Glutathione; Homocysteine; Ligases; Lipid Peroxidation; Liver; Methionine; Methionine Adenosyltransferase; Mice; Mice, Inbred C57BL; Putrescine; Receptors, Leptin; S-Adenosylmethionine; Spermidine; Taurine; Triglycerides; Up-Regulation

2013
DNA methylation potential: dietary intake and blood concentrations of one-carbon metabolites and cofactors in rural African women.
    The American journal of clinical nutrition, 2013, Volume: 97, Issue:6

    Topics: Adolescent; Adult; Betaine; Biomarkers; Choline; Cysteine; Diet; Diet Records; Dietary Carbohydrates; Dietary Fats; Dietary Proteins; DNA Methylation; Feeding Behavior; Female; Folic Acid; Gambia; Homocysteine; Humans; Linear Models; Methionine; Middle Aged; Nutrition Assessment; Prospective Studies; Riboflavin; Rural Population; S-Adenosylhomocysteine; S-Adenosylmethionine; Sarcosine; Vitamin B 12; Vitamin B 6; Young Adult

2013
The enzyme-mediated direct reversal of a dithymine photoproduct in germinating endospores.
    International journal of molecular sciences, 2013, Jun-25, Volume: 14, Issue:7

    Topics: Catalysis; Cysteine; DNA; DNA Repair; S-Adenosylmethionine

2013
Cysteine methylation controls radical generation in the Cfr radical AdoMet rRNA methyltransferase.
    PloS one, 2013, Volume: 8, Issue:7

    Topics: Cysteine; Deoxyadenosines; Electron Spin Resonance Spectroscopy; Escherichia coli Proteins; Free Radicals; Ligands; Methylation; Methyltransferases; Protein Binding; Recombinant Proteins; S-Adenosylmethionine

2013
Plasma sulfur amino acids and stearoyl-CoA desaturase activity in two Caucasian populations.
    Prostaglandins, leukotrienes, and essential fatty acids, 2013, Volume: 89, Issue:5

    Topics: Adipose Tissue; Aged; Aged, 80 and over; Amino Acids, Sulfur; Cohort Studies; Cross-Sectional Studies; Cystathionine; Cysteine; Diet; Dipeptides; Exercise; Fatty Acids; Female; Glutathione; Homocysteine; Humans; Male; Methionine; Middle Aged; S-Adenosylhomocysteine; S-Adenosylmethionine; Stearoyl-CoA Desaturase; Surveys and Questionnaires; White People

2013
Multiple inputs control sulfur-containing amino acid synthesis in Saccharomyces cerevisiae.
    Molecular biology of the cell, 2014, Volume: 25, Issue:10

    Topics: Basic-Leucine Zipper Transcription Factors; Cysteine; F-Box Proteins; Gene Expression Regulation, Fungal; Green Fluorescent Proteins; Methionine; Methionine Adenosyltransferase; Methylation; Phosphatidylcholines; Phosphatidylethanolamine N-Methyltransferase; Phosphatidylethanolamines; S-Adenosylmethionine; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Ubiquitin-Protein Ligase Complexes; Ubiquitination

2014
Food-derived opioid peptides inhibit cysteine uptake with redox and epigenetic consequences.
    The Journal of nutritional biochemistry, 2014, Volume: 25, Issue:10

    Topics: Animals; Antioxidants; Caco-2 Cells; Caseins; Cell Line, Tumor; Cysteine; DNA Methylation; Epigenesis, Genetic; Epithelial Cells; Gliadin; Glutathione; Humans; Hydrolysis; Intestinal Mucosa; Linear Models; Milk; Opioid Peptides; Oxidation-Reduction; S-Adenosylmethionine; Triticum

2014
Mutational analysis of the integral membrane methyltransferase isoprenylcysteine carboxyl methyltransferase (ICMT) reveals potential substrate binding sites.
    The Journal of biological chemistry, 2014, Sep-19, Volume: 289, Issue:38

    Topics: Amino Acid Sequence; Amino Acid Substitution; Animals; Anopheles; Catalytic Domain; Conserved Sequence; Cysteine; HEK293 Cells; Humans; Insect Proteins; Kinetics; Molecular Sequence Data; Mutagenesis, Site-Directed; Protein Binding; Protein Methyltransferases; S-Adenosylmethionine; Structural Homology, Protein

2014
Identification and characterization of arsenite methyltransferase from an archaeon, Methanosarcina acetivorans C2A.
    Environmental science & technology, 2014, Nov-04, Volume: 48, Issue:21

    Topics: Arsenic; Biotransformation; Cloning, Molecular; Conserved Sequence; Cysteine; Escherichia coli; Genes, Archaeal; Glutathione; Inactivation, Metabolic; Methanosarcina; Methylation; Methyltransferases; S-Adenosylmethionine; Sulfhydryl Compounds; Volatilization

2014
Sulfur amino acid metabolism in Zucker diabetic fatty rats.
    Biochemical pharmacology, 2015, Aug-01, Volume: 96, Issue:3

    Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Adenosylhomocysteinase; Animals; Area Under Curve; Betaine; Betaine-Homocysteine S-Methyltransferase; Cysteine; Dipeptides; Gene Expression Regulation; Glutamate-Cysteine Ligase; Glutathione; Homocysteine; Liver; Male; Methionine; Methylenetetrahydrofolate Reductase (NADPH2); Rats; Rats, Zucker; S-Adenosylhomocysteine; S-Adenosylmethionine; Spermidine; Spermine; Taurine

2015
NADPH oxidase 4 regulates homocysteine metabolism and protects against acetaminophen-induced liver damage in mice.
    Free radical biology & medicine, 2015, Volume: 89

    Topics: Acetaminophen; Analgesics, Non-Narcotic; Animals; Betaine; Blotting, Western; Cells, Cultured; Cysteine; Female; Glutathione; Hep G2 Cells; Homocysteine; Humans; Immunoenzyme Techniques; Liver; Liver Diseases; Methionine; Mice; Mice, Knockout; NADPH Oxidase 4; NADPH Oxidases; Reactive Oxygen Species; S-Adenosylmethionine

2015
CO and CN- syntheses by [FeFe]-hydrogenase maturase HydG are catalytically differentiated events.
    Proceedings of the National Academy of Sciences of the United States of America, 2016, Jan-05, Volume: 113, Issue:1

    Topics: Carbon Monoxide; Catalysis; Catalytic Domain; Cyanides; Cysteine; Desulfovibrio desulfuricans; Homocysteine; Hydrogenase; Iron-Sulfur Proteins; Ligands; Protein Structure, Secondary; S-Adenosylmethionine; Tyrosine

2016
The Radical SAM Enzyme HydG Requires Cysteine and a Dangler Iron for Generating an Organometallic Precursor to the [FeFe]-Hydrogenase H-Cluster.
    Journal of the American Chemical Society, 2016, Feb-03, Volume: 138, Issue:4

    Topics: Bacterial Proteins; Cysteine; Electron Spin Resonance Spectroscopy; Hydrogenase; Iron; Iron-Sulfur Proteins; Organometallic Compounds; S-Adenosylmethionine; Trans-Activators

2016
Biochemical and Spectroscopic Characterization of a Radical S-Adenosyl-L-methionine Enzyme Involved in the Formation of a Peptide Thioether Cross-Link.
    Biochemistry, 2016, Apr-12, Volume: 55, Issue:14

    Topics: Amino Acid Motifs; Amino Acid Substitution; Bacterial Proteins; Biocatalysis; Computational Biology; Cysteine; Cystine; Iron-Sulfur Proteins; Models, Molecular; Mutagenesis, Site-Directed; Mutation; Oxidation-Reduction; Oxidoreductases Acting on Sulfur Group Donors; Peptide Fragments; Protein Processing, Post-Translational; Recombinant Proteins; S-Adenosylmethionine; Substrate Specificity; Thermoanaerobacter

2016
Neuregulin 1 Promotes Glutathione-Dependent Neuronal Cobalamin Metabolism by Stimulating Cysteine Uptake.
    Oxidative medicine and cellular longevity, 2016, Volume: 2016

    Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Androstadienes; Cell Line, Tumor; Cysteine; Excitatory Amino Acid Transporter 3; Glutathione; Humans; Low Density Lipoprotein Receptor-Related Protein-2; Methylation; Neuregulin-1; Neurons; Real-Time Polymerase Chain Reaction; RNA, Messenger; S-Adenosylmethionine; Signal Transduction; Vitamin B 12; Wortmannin

2016
Crystallographic capture of a radical S-adenosylmethionine enzyme in the act of modifying tRNA.
    Science (New York, N.Y.), 2016, Apr-15, Volume: 352, Issue:6283

    Topics: Adenosine; Alanine; Amino Acid Substitution; Anticodon; Catalytic Domain; Crystallography, X-Ray; Cysteine; Escherichia coli Proteins; Methylation; Methyltransferases; Nucleic Acid Conformation; Protein Structure, Tertiary; RNA, Bacterial; RNA, Transfer, Glu; S-Adenosylmethionine

2016
Carbon-sulfur bond-forming reaction catalysed by the radical SAM enzyme HydE.
    Nature chemistry, 2016, Volume: 8, Issue:5

    Topics: Carbon; Catalysis; Catalytic Domain; Clostridium acetobutylicum; Cysteine; Free Radicals; Ligands; Models, Chemical; Oxidoreductases Acting on Sulfur Group Donors; Quantum Theory; S-Adenosylmethionine; Sulfur; Thermotoga maritima; Thiazolidines

2016
Cloning, expression and characterization of histidine-tagged biotin synthase of Mycobacterium tuberculosis.
    Tuberculosis (Edinburgh, Scotland), 2016, Volume: 98

    Topics: Antitubercular Agents; Bacterial Proteins; Biotin; Cloning, Molecular; Cysteine; Deoxyadenosines; Enzyme Inhibitors; Enzyme Stability; Histidine; Hydrogen-Ion Concentration; Kinetics; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Protein Engineering; Protein Multimerization; Recombinant Fusion Proteins; S-Adenosylhomocysteine; S-Adenosylmethionine; Substrate Specificity; Sulfurtransferases; Temperature

2016
Conserved cysteine residues determine substrate specificity in a novel As(III) S-adenosylmethionine methyltransferase from Aspergillus fumigatus.
    Molecular microbiology, 2017, Volume: 104, Issue:2

    Topics: Arsenic; Arsenicals; Arsenites; Aspergillus fumigatus; Conserved Sequence; Cysteine; Escherichia coli; Fungal Proteins; Methylation; Methyltransferases; S-Adenosylmethionine; Substrate Specificity

2017
A Metabolic Function for Phospholipid and Histone Methylation.
    Molecular cell, 2017, Apr-20, Volume: 66, Issue:2

    Topics: Cysteine; Energy Metabolism; Gene Expression Profiling; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Fungal; Histones; Lysine; Methylation; Mutation; Oxidative Stress; Phosphatidylcholines; Phosphatidylethanolamine N-Methyltransferase; Phosphatidylethanolamines; Protein Phosphatase 2; Protein Processing, Post-Translational; S-Adenosylhomocysteine; S-Adenosylmethionine; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Time Factors; Transcription, Genetic

2017
Human Viperin Causes Radical SAM-Dependent Elongation of Escherichia coli, Hinting at Its Physiological Role.
    Biochemistry, 2017, 08-01, Volume: 56, Issue:30

    Topics: Amino Acid Substitution; Bacterial Adhesion; Cysteine; Escherichia coli; Escherichia coli Proteins; Host-Pathogen Interactions; Humans; Kinetics; Microscopy, Confocal; Mutagenesis, Site-Directed; Mutation; Oxidoreductases Acting on CH-CH Group Donors; Peptide Fragments; Periplasmic Binding Proteins; Protein Interaction Domains and Motifs; Protein Stability; Proteins; Recombinant Fusion Proteins; S-Adenosylmethionine

2017
TsrM as a Model for Purifying and Characterizing Cobalamin-Dependent Radical S-Adenosylmethionine Methylases.
    Methods in enzymology, 2017, Volume: 595

    Topics: Bacterial Proteins; Biocatalysis; Coenzymes; Cysteine; Escherichia coli; Iron-Sulfur Proteins; Methylation; Methyltransferases; Protein Binding; S-Adenosylmethionine; Small Ubiquitin-Related Modifier Proteins; Tryptophan; Vitamin B 12

2017
Crystal structure of cystathionine β-synthase from honeybee Apis mellifera.
    Journal of structural biology, 2018, Volume: 202, Issue:1

    Topics: Amino Acid Sequence; Animals; Bees; Crystallography, X-Ray; Cystathionine beta-Synthase; Cysteine; Homocysteine; Humans; Insect Proteins; Models, Molecular; Protein Conformation; Protein Multimerization; S-Adenosylmethionine; Sequence Homology, Amino Acid; Substrate Specificity

2018
Atomic structure of the eukaryotic intramembrane RAS methyltransferase ICMT.
    Nature, 2018, 01-25, Volume: 553, Issue:7689

    Topics: Animals; Catalytic Domain; Coenzymes; Crystallography, X-Ray; Cysteine; Drug Design; Endoplasmic Reticulum; Membrane Lipids; Models, Molecular; Protein Methyltransferases; S-Adenosylmethionine; Substrate Specificity; Tribolium

2018
miCLIP-MaPseq, a Substrate Identification Approach for Radical SAM RNA Methylating Enzymes.
    Journal of the American Chemical Society, 2018, 06-13, Volume: 140, Issue:23

    Topics: Adenosine; Cysteine; Escherichia coli; Escherichia coli Proteins; Immunoprecipitation; Methylation; Methyltransferases; Mutation; RNA; S-Adenosylmethionine; Sequence Analysis, RNA; Substrate Specificity

2018
Investigation of Solvent Hydron Exchange in the Reaction Catalyzed by the Antibiotic Resistance Protein Cfr.
    Biochemistry, 2018, 07-31, Volume: 57, Issue:30

    Topics: Biocatalysis; Cysteine; Drug Resistance, Microbial; Escherichia coli; Escherichia coli Infections; Escherichia coli Proteins; Humans; Methylation; Methyltransferases; RNA, Ribosomal, 23S; S-Adenosylmethionine; Water

2018
Spectroscopic and Electrochemical Characterization of the Mycofactocin Biosynthetic Protein, MftC, Provides Insight into Its Redox Flipping Mechanism.
    Biochemistry, 2019, 02-19, Volume: 58, Issue:7

    Topics: Bacterial Proteins; Catalysis; Catalytic Domain; Cysteine; Electrochemical Techniques; Electron Spin Resonance Spectroscopy; Iron-Sulfur Proteins; Mycobacterium ulcerans; Oxidation-Reduction; S-Adenosylmethionine; Spectroscopy, Mossbauer

2019
Radical S-adenosylmethionine maquette chemistry: Cx
    Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry, 2019, Volume: 24, Issue:6

    Topics: C-Peptide; Cysteine; Ferredoxins; Iron-Sulfur Proteins; S-Adenosylmethionine

2019
Blockade of the trans-sulfuration pathway in acute pancreatitis due to nitration of cystathionine β-synthase.
    Redox biology, 2020, Volume: 28

    Topics: Animals; Ceruletide; Cystathionine; Cystathionine beta-Synthase; Cysteine; Disease Models, Animal; Glutathione; Homocysteine; Male; Mice; Nitric Oxide Synthase Type II; Pancreatitis; S-Adenosylmethionine; Up-Regulation

2020
Transsulfuration Activity Can Support Cell Growth upon Extracellular Cysteine Limitation.
    Cell metabolism, 2019, 11-05, Volume: 30, Issue:5

    Topics: A549 Cells; Animals; Cell Proliferation; Cysteine; Extracellular Space; Female; Gene Knockout Techniques; Hep G2 Cells; Heterografts; Humans; Male; MCF-7 Cells; Methionine; Mice; Mice, Inbred NOD; Mice, Nude; Mice, SCID; Neoplasms; Protamines; S-Adenosylhomocysteine; S-Adenosylmethionine; Serine; Tumor Burden

2019
Structural Insights into the Mechanism of the Radical SAM Carbide Synthase NifB, a Key Nitrogenase Cofactor Maturating Enzyme.
    Journal of the American Chemical Society, 2020, 06-24, Volume: 142, Issue:25

    Topics: Archaeal Proteins; Binding Sites; Crystallography, X-Ray; Cysteine; Glutamic Acid; Histidine; Iron-Sulfur Proteins; Methanosarcinales; Models, Chemical; Oxidoreductases; Protein Binding; Protein Conformation; S-Adenosylmethionine

2020
Biochemical and Mutational Analysis of Radical
    Biochemistry, 2021, 09-28, Volume: 60, Issue:38

    Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Adenosine; Bacterial Proteins; Catalysis; Cysteine; S-Adenosylmethionine; Triterpenes; Zymomonas

2021
Selenocysteine substitutions in thiyl radical enzymes.
    Methods in enzymology, 2022, Volume: 662

    Topics: Cysteine; Proteomics; S-Adenosylmethionine; Selenocysteine; Selenoproteins

2022
Dioxane Bridge Formation during the Biosynthesis of Spectinomycin Involves a Twitch Radical
    Journal of the American Chemical Society, 2022, 06-08, Volume: 144, Issue:22

    Topics: Cysteine; Oxidoreductases; Phylogeny; Racemases and Epimerases; S-Adenosylmethionine; Spectinomycin

2022
Methionine Deprivation Reveals the Pivotal Roles of Cell Cycle Progression in Ferroptosis That Is Induced by Cysteine Starvation.
    Cells, 2022, 05-10, Volume: 11, Issue:10

    Topics: Cell Cycle; Cysteine; Cystine; Ferroptosis; Glutathione; HeLa Cells; Humans; Methionine; Reactive Oxygen Species; S-Adenosylmethionine

2022
    Science advances, 2022, 06-24, Volume: 8, Issue:25

    Topics: Animals; Cryoelectron Microscopy; Cystathionine beta-Synthase; Cysteine; Methionine; Mice; Mycobacterium tuberculosis; Oxidation-Reduction; Pyridoxal Phosphate; S-Adenosylmethionine; Sulfur

2022
Plasma One-Carbon Metabolism-Related Micronutrients and the Risk of Breast Cancer: Involvement of DNA Methylation.
    Nutrients, 2023, Aug-17, Volume: 15, Issue:16

    Topics: Breast Neoplasms; Carbon; Case-Control Studies; Choline; Cysteine; DNA Methylation; Female; Folic Acid; Humans; Methionine; Micronutrients; Racemethionine; S-Adenosylmethionine; Trace Elements

2023
Methionine-CBS axis promotes intracellular ROS levels by reprogramming serine metabolism.
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2023, Volume: 37, Issue:12

    Topics: Cysteine; Methionine; Racemethionine; Reactive Oxygen Species; S-Adenosylmethionine; Serine

2023
Formaldehyde regulates
    Science (New York, N.Y.), 2023, 11-03, Volume: 382, Issue:6670

    Topics: Animals; Carbon; Cysteine; Environmental Exposure; Epigenesis, Genetic; Formaldehyde; Hep G2 Cells; Humans; Methionine Adenosyltransferase; Mice; Protein Isoforms; S-Adenosylmethionine

2023