cysteine has been researched along with s-(1,1,2,2-tetrafluoroethyl)cysteine in 30 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 18 (60.00) | 18.2507 |
| 2000's | 12 (40.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Chen, Q; Stevens, JL; Yu, K | 1 |
| Anders, MW; Hargus, SJ | 1 |
| Dulik, DM; Hayden, PJ; McCann, DJ; Stevens, JL; Ward, AJ; Yang, Y | 1 |
| Hayden, PJ; Ichimura, T; McCann, DJ; Pohl, LR; Stevens, JL | 1 |
| Anders, MW; Harris, JW | 1 |
| Groves, CE; Lock, EA; Schnellmann, RG | 1 |
| Chen, JC; Jones, TW; Stevens, JL; Trifillis, AL | 1 |
| Ichimura, T; Maciag, T; Maier, JA; Stevens, JL; Zhang, G | 2 |
| Bruschi, SA; Crabb, JW; Gupta, RS; Stevens, JL; West, KA | 1 |
| Lock, EA; Miller, GW; Schnellmann, RG | 1 |
| Groves, CE; Hayden, PJ; Lock, EA; Schnellmann, RG | 1 |
| Schnellmann, RG; Yang, X | 1 |
| Asano, Y; Cooper, AJ; Kato, Y | 1 |
| Halleck, MM; Liu, H; North, J; Stevens, JL | 1 |
| Ishmael, J; Lock, EA | 1 |
| Bruschi, SA; Crabb, JW; Lindsay, JG | 1 |
| Bunik, V; Cooper, AJ; Gibson, GE; Park, LC | 1 |
| Elliott, GS; Keller, DA; Kelly, DP; Kennedy, GL; Ross, PE | 1 |
| Bruschi, SA; Cooper, AJ; Gartner, CA; Wang, J | 1 |
| Adams, ML; Aebersold, RH; Bruschi, SA; Fausto, N; Gygi, SP; James, EA; Nelson, SD; Pierce, RH | 1 |
| Bruschi, SA; Cooper, AJ; Iriarte, A; Martinez-Carrion, M | 1 |
| Anders, MW; Bruschi, SA; Cooper, AJ | 1 |
| Bruschi, SA; Conway, M; Cooper, AJ; Hutson, SM | 1 |
| Hawksworth, GM; Lock, EA; McGoldrick, TA; Rodilla, V | 1 |
| Cooper, AJ; Jeitner, TM; Krasnikov, BF; Okuno, E | 1 |
| Bonventre, JV; Hung, CC; Ichimura, T; Stevens, JL; Yang, SA | 1 |
| Bruschi, SA; Fausto, N; Fernandez, C; Ho, HK; Kavanagh, TJ; Nelson, SD; White, CC | 1 |
| Asmellash, S; Ichimura, T; Stevens, JL | 1 |
| Bammler, TK; Beyer, RP; Bruschi, SA; Coe, KJ; Doneanu, CE; Fausto, N; Gao, Q; Ho, HK; Hu, Z; Jia, Y; Nelson, SD | 1 |
1 review(s) available for cysteine and s-(1,1,2,2-tetrafluoroethyl)cysteine
| Article | Year |
|---|---|
Toxic, halogenated cysteine S-conjugates and targeting of mitochondrial enzymes of energy metabolism.
Topics: Animals; Carbon-Sulfur Lyases; Cysteine; Energy Metabolism; Humans; Hydrocarbons, Fluorinated; Lyases; Mitochondria; Pyridoxal Phosphate | 2002 |
29 other study(ies) available for cysteine and s-(1,1,2,2-tetrafluoroethyl)cysteine
| Article | Year |
|---|---|
Regulation of the cellular stress response by reactive electrophiles. The role of covalent binding and cellular thiols in transcriptional activation of the 70-kilodalton heat shock protein gene by nephrotoxic cysteine conjugates.
Topics: Aminooxyacetic Acid; Animals; Calcium; Cell Line; Cycloheximide; Cysteine; Dactinomycin; Dithiothreitol; Gene Expression Regulation; Heat-Shock Proteins; Hydrocarbons, Fluorinated; Kidney; Kinetics; Lipid Peroxidation; Molecular Weight; Protein Conformation; RNA, Messenger; Signal Transduction; Transcription, Genetic | 1992 |
Immunochemical detection of covalently modified kidney proteins in S-(1,1,2,2-tetrafluoroethyl)-L-cysteine-treated rats.
Topics: Aminooxyacetic Acid; Animals; Cross Reactions; Cysteine; Cytosol; Dose-Response Relationship, Drug; Hydrocarbons, Fluorinated; Immunoblotting; Kidney; Mitochondria; Proteins; Rats; Time Factors | 1991 |
Formation of difluorothionoacetyl-protein adducts by S-(1,1,2,2-tetrafluoroethyl)-L-cysteine metabolites: nucleophilic catalysis of stable lysyl adduct formation by histidine and tyrosine.
Topics: Amines; Amino Acids; Animals; Carbon Isotopes; Carbon-Sulfur Lyases; Cysteine; Cytosol; Fluorine; Histidine; Hydrocarbons, Fluorinated; Kidney Cortex; Kidney Tubules, Proximal; Kinetics; Lyases; Lysine; Magnetic Resonance Spectroscopy; Male; Phenols; Protein Binding; Rats; Rats, Inbred Strains; Serum Albumin, Bovine; Spectrometry, Mass, Fast Atom Bombardment; Tyrosine | 1991 |
Detection of cysteine conjugate metabolite adduct formation with specific mitochondrial proteins using antibodies raised against halothane metabolite adducts.
Topics: Acetamides; Animals; Cross Reactions; Cysteine; Enzyme-Linked Immunosorbent Assay; Fluoroacetates; Halothane; Hydrocarbons, Fluorinated; Immunoblotting; Immunohistochemistry; Kidney Diseases; Kidney Tubules, Proximal; Kinetics; Male; Mitochondria; Rats; Rats, Inbred Strains; Trifluoroacetic Acid | 1991 |
The use of 19F NMR in the study of protein alkylation by fluorinated reactive intermediates.
Topics: Alkylation; Animals; Cysteine; Fluorine; Hydrocarbons, Fluorinated; In Vitro Techniques; Kidney; Magnetic Resonance Spectroscopy; Male; Proteins; Rats; Rats, Inbred Strains | 1991 |
The effects of haloalkene cysteine conjugates on cytosolic free calcium levels in suspensions of rat renal proximal tubules.
Topics: Animals; Butadienes; Calcium; Cysteine; Cytosol; Homocysteine; Hydrocarbons, Fluorinated; In Vitro Techniques; Kidney Tubules, Proximal; Male; Oxygen Consumption; Rats; Rats, Inbred Strains | 1990 |
Renal cysteine conjugate beta-lyase-mediated toxicity studied with primary cultures of human proximal tubular cells.
Topics: Adolescent; Adult; Aminooxyacetic Acid; Butadienes; Carbon-Sulfur Lyases; Cells, Cultured; Child; Cysteine; Dose-Response Relationship, Drug; Epithelial Cells; Female; Glutathione; Humans; Hydrocarbons, Fluorinated; Kidney Tubules, Proximal; Lyases; Male; Middle Aged; Structure-Activity Relationship | 1990 |
FGF-1 in normal and regenerating kidney: expression in mononuclear, interstitial, and regenerating epithelial cells.
Topics: Animals; Cell Differentiation; Cell Division; Cysteine; Epithelial Cells; Epithelium; Fibroblast Growth Factors; Hydrocarbons, Fluorinated; Immunohistochemistry; Kidney Tubules, Proximal; Male; Rats; Rats, Inbred F344; Regeneration; Time Factors; Vimentin | 1995 |
A role for fibroblast growth factor type-1 in nephrogenic repair. Autocrine expression in rat kidney proximal tubule epithelial cells in vitro and in the regenerating epithelium following nephrotoxic damage by S-(1,1,2,2-tetrafluoroethyl)-L-cysteine in vi
Topics: Animals; Biological Assay; Cell Differentiation; Cell Division; Cells, Cultured; Cysteine; Endothelium, Vascular; Epithelium; Fibroblast Growth Factor 1; Fibroblast Growth Factor 2; Humans; Hydrocarbons, Fluorinated; Immunohistochemistry; Kidney Tubules, Proximal; Kinetics; Rats; Regeneration; RNA, Messenger; Thymidine; Time Factors; Umbilical Veins; Wounds and Injuries | 1993 |
Mitochondrial HSP60 (P1 protein) and a HSP70-like protein (mortalin) are major targets for modification during S-(1,1,2,2-tetrafluoroethyl)-L-cysteine-induced nephrotoxicity.
Topics: Amino Acid Sequence; Animals; Aspartate Aminotransferases; Chaperonins; Cysteine; Heat-Shock Proteins; HSP70 Heat-Shock Proteins; Hydrocarbons, Fluorinated; Kidney; Male; Mitochondria; Molecular Sequence Data; Precipitin Tests; Proteins; Rats; Rats, Inbred F344 | 1993 |
Strychnine and glycine protect renal proximal tubules from various nephrotoxicants and act in the late phase of necrotic cell injury.
Topics: Animals; Antimycin A; Cell Death; Cysteine; Glycine; Hydrocarbons, Fluorinated; Hydroquinones; In Vitro Techniques; Kidney Tubules, Proximal; L-Lactate Dehydrogenase; Necrosis; Peroxides; Rabbits; Sodium Cyanide; Strychnine; tert-Butylhydroperoxide | 1994 |
Differential cellular effects in the toxicity of haloalkene and haloalkane cysteine conjugates to rabbit renal proximal tubules.
Topics: Aminooxyacetic Acid; Animals; Biotransformation; Cell Death; Cysteine; Female; Hydrocarbons, Fluorinated; Hydrocarbons, Halogenated; In Vitro Techniques; Kidney Tubules, Proximal; Lipid Peroxidation; Mitochondria; Oxygen Consumption; Rabbits; Sulfur Radioisotopes | 1993 |
Proteinases in renal cell death.
Topics: Animals; Anti-Bacterial Agents; Antimycin A; Antipain; Carboxypeptidases; Cathepsin A; Cathepsin B; Cell Death; Coumarins; Cysteine; Cysteine Proteinase Inhibitors; Dose-Response Relationship, Drug; Endopeptidases; Hydrocarbons, Fluorinated; Hydroquinones; Isocoumarins; Kidney Tubules, Proximal; L-Lactate Dehydrogenase; Leucine; Leupeptins; Lysosomes; Membrane Potentials; Pepstatins; Peroxides; Rabbits; Reactive Oxygen Species; Serine Proteinase Inhibitors; tert-Butylhydroperoxide; Tosyllysine Chloromethyl Ketone | 1996 |
Inactivation of brain and kidney aspartate aminotransferases by S-(1,2,-dichlorovinyl)-L-cysteine and by S-(1,1,2,2,-tetrafluoroethyl)-L-cysteine.
Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Brain; Cysteine; Cytosol; Enzyme Activation; Hydrocarbons, Fluorinated; Kidney; Male; Mitochondria; Myocardium; Rats; Rats, Wistar; Swine | 1996 |
Reduction of trans-4,5-dihydroxy-1,2-dithiane by cellular oxidoreductases activates gadd153/chop and grp78 transcription and induces cellular tolerance in kidney epithelial cells.
Topics: Animals; Carrier Proteins; CCAAT-Enhancer-Binding Proteins; Cell Line; Cell Survival; Cysteine; Disulfides; Dithiothreitol; DNA Damage; DNA-Binding Proteins; Endoplasmic Reticulum Chaperone BiP; Heat-Shock Proteins; Heterocyclic Compounds; Heterocyclic Compounds, 1-Ring; Hydrocarbons, Fluorinated; Molecular Chaperones; Nuclear Proteins; Oxidation-Reduction; Oxidoreductases; Protein Processing, Post-Translational; Radiation-Protective Agents; Stress, Physiological; Transcription Factor CHOP; Transcription Factors; Transcription, Genetic | 1997 |
The nephrotoxicity and hepatotoxicity of 1,1,2,2-tetrafluoroethyl-L-cysteine in the rat.
Topics: Acetylcysteine; Aminooxyacetic Acid; Animals; Butadienes; Cysteine; Dose-Response Relationship, Drug; Female; Hydrocarbons, Fluorinated; Ion Transport; Kidney Diseases; Male; Probenecid; Rats; Renal Agents | 1998 |
Mitochondrial stress protein recognition of inactivated dehydrogenases during mammalian cell death.
Topics: Acyltransferases; Animals; Cell Death; Cysteine; Dihydrolipoamide Dehydrogenase; Heat-Shock Proteins; Hydrocarbons, Fluorinated; Ketoglutarate Dehydrogenase Complex; Kidney; Mitochondria; Rats | 1998 |
Inhibition of select mitochondrial enzymes in PC12 cells exposed to S-(1,1,2,2-tetrafluoroethyl)-L-cysteine.
Topics: Animals; Carbon-Sulfur Lyases; Cysteine; Energy Metabolism; Enzyme Inhibitors; Hydrocarbons, Fluorinated; Ketoglutarate Dehydrogenase Complex; Mitochondria, Heart; PC12 Cells; Pyruvate Dehydrogenase Complex; Rats; Transaminases | 1999 |
Toxicity of tetrafluoroethylene and S-(1,1,2, 2-tetrafluoroethyl)-L-cysteine in rats and mice.
Topics: Administration, Inhalation; Animals; Body Weight; Cell Division; Cysteine; Female; Fluorocarbons; Hydrocarbons, Fluorinated; Kidney; Liver; Mice; Organ Size; Rats; Rats, Inbred F344; Species Specificity | 2000 |
Co-purification of mitochondrial HSP70 and mature protein disulfide isomerase with a functional rat kidney high-M(r) cysteine S-conjugate beta-lyase.
Topics: Animals; Carbon-Sulfur Lyases; Cysteine; Enzyme Inhibitors; HSP70 Heat-Shock Proteins; Hydrocarbons, Fluorinated; Kidney; Male; Mitochondria; Protein Disulfide-Isomerases; Rats; Rats, Inbred F344; Sequence Analysis, Protein | 2001 |
Mitochondrial aconitase modification, functional inhibition, and evidence for a supramolecular complex of the TCA cycle by the renal toxicant S-(1,1,2,2-tetrafluoroethyl)-L-cysteine.
Topics: Aconitate Hydratase; Animals; Carbon-Sulfur Lyases; Citric Acid Cycle; Cysteine; Hydrocarbons, Fluorinated; Ketoglutarate Dehydrogenase Complex; Kidney; Male; Mice; Mitochondria; Rats; Rats, Inbred F344; Tumor Cells, Cultured | 2002 |
Mitochondrial aspartate aminotransferase catalyses cysteine S-conjugate beta-lyase reactions.
Topics: Animals; Aspartate Aminotransferase, Mitochondrial; beta-Alanine; Carbon-Sulfur Lyases; Catalysis; Cysteine; Hydrocarbons, Fluorinated; Kidney; Liver; Male; Myocardium; Rats; Rats, Inbred F344; Subcellular Fractions; Substrate Specificity; Swine; Thiosulfates | 2002 |
Human mitochondrial and cytosolic branched-chain aminotransferases are cysteine S-conjugate beta-lyases, but turnover leads to inactivation.
Topics: Ammonia; beta-Alanine; Carbon-Sulfur Lyases; Cysteine; Cytosol; Halogens; Humans; Hydrocarbons, Fluorinated; Keto Acids; Leucine; Mitochondria; Pyruvic Acid; Recombinant Proteins; Substrate Specificity; Temperature; Transaminases | 2003 |
Renal cysteine conjugate C-S lyase mediated toxicity of halogenated alkenes in primary cultures of human and rat proximal tubular cells.
Topics: Animals; Cells, Cultured; Cysteine; Glutathione; Humans; Hydrocarbons, Fluorinated; Kidney Tubules, Proximal; Lyases; Rats; Species Specificity; Time Factors; Urothelium | 2003 |
L-alanine-glyoxylate aminotransferase II of rat kidney and liver mitochondria possesses cysteine S-conjugate beta-lyase activity: a contributing factor to the nephrotoxicity/hepatotoxicity of halogenated alkenes?
Topics: Alkenes; Amino Acids; Animals; beta-Alanine; Binding Sites; Carbon-Sulfur Lyases; Cysteine; Environmental Pollutants; Hydrocarbons, Fluorinated; Hydrocarbons, Halogenated; Kidney; Kinetics; Liver; Male; Mitochondria; Mitochondria, Liver; Pyruvic Acid; Rats; Rats, Inbred BN; Rats, Inbred F344; Transaminases | 2003 |
Kidney injury molecule-1: a tissue and urinary biomarker for nephrotoxicant-induced renal injury.
Topics: Animals; Biomarkers; Cell Adhesion Molecules; Cisplatin; Cysteine; Folic Acid; Hydrocarbons, Fluorinated; Immunohistochemistry; Kidney; Kidney Diseases; Male; Membrane Proteins; Rats; Rats, Inbred F344; Rats, Sprague-Dawley | 2004 |
Nrf2 activation involves an oxidative-stress independent pathway in tetrafluoroethylcysteine-induced cytotoxicity.
Topics: Adenosine Triphosphate; Animals; Calcium; Cell Line; Cell Survival; Cysteine; DNA-Binding Proteins; Gene Expression Profiling; Gene Expression Regulation; Glutathione; Hydrocarbons, Fluorinated; Hydrogen Peroxide; Mice; NF-E2-Related Factor 2; Oligonucleotide Array Sequence Analysis; Oxidative Stress; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Trans-Activators | 2005 |
Modulating the endoplasmic reticulum stress response with trans-4,5-dihydroxy-1,2-dithiane prevents chemically induced renal injury in vivo.
Topics: Animals; Cysteine; Disulfides; Dose-Response Relationship, Drug; Endoplasmic Reticulum; Epithelial Cells; Gene Expression Regulation; Heat-Shock Proteins; Heterocyclic Compounds; Heterocyclic Compounds, 1-Ring; HSP70 Heat-Shock Proteins; Hydrocarbons, Fluorinated; Kidney Diseases; Kidney Tubules, Proximal; Male; Molecular Chaperones; Oxidative Stress; Rats; Rats, Inbred F344; RNA, Antisense | 2005 |
Cytosolic heat shock proteins and heme oxygenase-1 are preferentially induced in response to specific and localized intramitochondrial damage by tetrafluoroethylcysteine.
Topics: Cell Line; Cell Survival; Cysteine; Cytosol; Dimerization; Gene Expression; Gene Silencing; Heat-Shock Proteins; Heme Oxygenase-1; Hepatocytes; Hydrocarbons, Fluorinated; Mitochondria, Liver; Protein Array Analysis; Protein Processing, Post-Translational; RNA, Messenger; RNA, Small Interfering; Transfection; Up-Regulation | 2006 |