cysteine has been researched along with quinazolines in 24 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (8.33) | 18.7374 |
| 1990's | 2 (8.33) | 18.2507 |
| 2000's | 7 (29.17) | 29.6817 |
| 2010's | 10 (41.67) | 24.3611 |
| 2020's | 3 (12.50) | 2.80 |
| Authors | Studies |
|---|---|
| Maley, F; Maley, GF | 1 |
| Ebata, M; Miyazaki, K; Otsuka, H | 1 |
| Changchien, L; Lobo, AP; Maley, F; Montfort, WR; Nair, MG; Weichsel, A | 1 |
| Bridges, AJ; Denny, WA; Dobrusin, EM; Doherty, A; Fry, DW; Greis, KD; Hicks, JL; Hook, KE; Keller, PR; Leopold, WR; Loo, JA; McNamara, DJ; Nelson, JM; Sherwood, V; Smaill, JB; Trumpp-Kallmeyer, S | 1 |
| Sule, SD; Wigley, FM | 1 |
| Almog, R; Maley, F; Maley, GF; Van Roey, P; Waddling, CA | 1 |
| Bernhardt, G; Buschauer, A; Gartner, M; Giannis, A; Gross, D; Müller, C; Sarli, V | 1 |
| Rusk, N | 1 |
| Hamid, Q; Hassan, M; Jo, T; Martin, JG; McGovern, T; Ramos-Barbón, D; Tamaoka, M; Tolloczko, B; Yoshizawa, Y | 1 |
| Balk, SP; Didonato, M; Flatauer, L; Gray, NS; Hur, W; Jiang, X; Kim, S; Larson, B; Mason, DE; Nagle, A; Peters, EC; Suzuki, M; Valente, D; Velentza, A; Warmuth, M; Zagorska, A; Zhang, J | 1 |
| Angelo, LS; Gong, J; Kohanim, S; Kurzrock, R; Yang, DJ | 1 |
| Good, JA; Kaan, HY; Kozielski, F; MacKay, SP; Podgórski, D; Rath, O; Talapatra, SK; Wang, F | 1 |
| DeBonis, S; Garcia-Saez, I; Indorato, RL; Kozielski, F; Skoufias, DA | 1 |
| Hardy, KD; Nelson, SD; Papageorgiou, I; Rettie, AE; Unadkat, JD; Wahlin, MD | 1 |
| Almaden, C; Bergqvist, S; Bolanos, B; Dalvie, D; Feng, J; Kath, JC; Kuzmic, P; Murray, BW; Nagata, A; Ryan, K; Schwartz, PA; Solowiej, J; Wani, R; Xu, M | 1 |
| Anand, T; Chellappa, D; Sivaraman, G | 1 |
| Capoferri, L; Lodola, A; Mor, M; Rivara, S | 1 |
| Cao, XJ; Garcia, BA; Kharbanda, A; Runkle, KB; Stypulkowski, E; Wang, W; Witze, ES | 1 |
| Kharbanda, A; Runkle, K; Wang, W; Witze, ES | 1 |
| Anderson, KS; Bierbach, U; Chu, J; Furdui, CM; Gabriel, LA; Kim, Y; Wu, H; Yang, M | 1 |
| Abe, Y; Caaveiro, JMM; Fuchida, H; Hamachi, I; Hatsuyama, Y; Koyanagi, S; Kuwata, K; Matsunaga, N; Miura, C; Morimoto, S; Nakao, T; Ohdo, S; Ojida, A; Okamoto, K; Ono, M; Sakamoto, S; Sato, M; Shibata, T; Shindo, N; Shiroishi, M; Tamura, T; Tokunaga, K; Ueda, T; Watari, K; Yamaguchi, Y | 1 |
| Chen, J; Li, L; Liao, H; Liu, J; Zhao, H | 1 |
| Biswal, BK; Panda, M | 1 |
| Chiotellis, A; Kiritsis, C; Makrypidi, K; Papadopoulos, M; Paravatou-Petsotas, M; Pelecanou, M; Pirmettis, I; Roupa, I; Shegani, A; Triantopoulou, S | 1 |
1 review(s) available for cysteine and quinazolines
| Article | Year |
|---|---|
Novel therapy in the treatment of scleroderma.
Topics: Autoimmune Diseases; Bone Marrow Transplantation; Cysteine; Humans; Interferon-gamma; Nitric Oxide; Piperidines; Prostaglandins; Quinazolines; Quinazolinones; Relaxin; Scleroderma, Systemic; Tetracycline; Transforming Growth Factor beta; Tumor Necrosis Factor-alpha | 2001 |
23 other study(ies) available for cysteine and quinazolines
| Article | Year |
|---|---|
Properties of a defined mutant of Escherichia coli thymidylate synthase.
Topics: Amino Acids; Cysteine; Escherichia coli; Fluorodeoxyuridylate; Folic Acid; Mutation; Peptide Mapping; Quinazolines; Structure-Activity Relationship; Tetrahydrofolates; Thymidylate Synthase; Tyrosine | 1988 |
Studi on siomycin. II. The composition and degradation products of siomycin A.
Topics: Acetaldehyde; Alanine; Amino Acids; Anti-Bacterial Agents; Butyrates; Carbon; Chemical Phenomena; Chemistry; Cysteine; Optical Rotatory Dispersion; Oxidation-Reduction; Propionates; Pyruvates; Quinazolines; Thiazoles; Threonine; Valine | 1969 |
Mode of action of site-directed irreversible folate analogue inhibitors of thymidylate synthase.
Topics: Amino Acid Sequence; Binding Sites; Cysteine; Enzyme Inhibitors; Escherichia coli; Folic Acid; Glutamic Acid; Kinetics; Molecular Sequence Data; Pyrimidines; Quinazolines; Thymidylate Synthase | 1998 |
Specific, irreversible inactivation of the epidermal growth factor receptor and erbB2, by a new class of tyrosine kinase inhibitor.
Topics: Animals; Antineoplastic Agents; Binding Sites; Cell Line; Cysteine; Enzyme Inhibitors; ErbB Receptors; Humans; Mice; Mice, Nude; Models, Molecular; Mutagenesis, Site-Directed; Neoplasm Transplantation; Neoplasms, Experimental; Protein Conformation; Protein-Tyrosine Kinases; Quinazolines; Receptor, ErbB-2; Recombinant Fusion Proteins; Transplantation, Heterologous; Tumor Cells, Cultured | 1998 |
Crystal structure of a deletion mutant of human thymidylate synthase Delta (7-29) and its ternary complex with Tomudex and dUMP.
Topics: Binding Sites; Catalytic Domain; Crystallography, X-Ray; Cysteine; Deoxyuracil Nucleotides; Drug Design; Enzyme Inhibitors; Escherichia coli; Humans; Models, Molecular; Protein Binding; Protein Structure, Secondary; Quinazolines; Sequence Deletion; Structure-Activity Relationship; Thiophenes; Thymidylate Synthase | 2001 |
Inhibitors of kinesin Eg5: antiproliferative activity of monastrol analogues against human glioblastoma cells.
Topics: Acridines; Antineoplastic Agents, Phytogenic; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cell Line, Tumor; Cell Proliferation; Cell Survival; Cysteine; Dose-Response Relationship, Drug; Flow Cytometry; Fluoresceins; Glioblastoma; Humans; Insecticides; Kinesins; Molecular Structure; Paclitaxel; Pyrimidines; Quinazolines; Rotenone; Spindle Apparatus; Tetrahydroisoquinolines; Thiones; Time Factors; Tubulin; Tubulin Modulators; Vinblastine | 2007 |
Kinase clamping.
Topics: Cysteine; Phosphotransferases; Point Mutation; Quinazolines | 2007 |
The epidermal growth factor receptor mediates allergic airway remodelling in the rat.
Topics: Allergens; Animals; Cell Proliferation; Cysteine; ErbB Receptors; Gene Expression Profiling; Goblet Cells; Hyperplasia; Inflammation; Leukotriene D4; Muscle, Smooth; Ovalbumin; Quinazolines; Rats; Receptors, Leukotriene; Tyrphostins | 2008 |
Clinical stage EGFR inhibitors irreversibly alkylate Bmx kinase.
Topics: Animals; Cysteine; ErbB Receptors; Mice; Molecular Structure; Morpholines; Protein-Tyrosine Kinases; Quinazolines; Sequence Homology, Amino Acid | 2008 |
Molecular imaging of gefitinib activity in an epidermal growth factor receptor (EGFR)-bearing xenograft model.
Topics: Animals; Apoptosis; Blotting, Western; Cell Line, Tumor; Cysteine; ErbB Receptors; Female; Flow Cytometry; Gefitinib; Humans; Immunoprecipitation; Indium Radioisotopes; Mice; Mice, Nude; Molecular Imaging; Neoplasms, Glandular and Epithelial; Phosphorylation; Protein Kinase Inhibitors; Quinazolines; Radionuclide Imaging; Technetium; Tissue Distribution; Xenograft Model Antitumor Assays | 2009 |
Optimized S-trityl-L-cysteine-based inhibitors of kinesin spindle protein with potent in vivo antitumor activity in lung cancer xenograft models.
Topics: Animals; Antineoplastic Agents; Benzamides; Butylamines; Cell Line, Tumor; Chromones; Cysteine; Kinesins; Lung Neoplasms; Mice; Mice, Nude; Neoplasm Transplantation; Quinazolines; Structure-Activity Relationship; Transplantation, Heterologous | 2013 |
STLC-resistant cell lines as tools to classify chemically divergent Eg5 targeting agents according to their mode of action and target specificity.
Topics: Adenosine Triphosphatases; Adenosine Triphosphate; Allosteric Site; Antineoplastic Agents; Binding Sites; Cell Line, Tumor; Cell Proliferation; Cysteine; Drug Resistance, Neoplasm; Humans; Kinesins; M Phase Cell Cycle Checkpoints; Point Mutation; Quinazolines; Thiadiazoles; Thiones | 2013 |
Studies on the role of metabolic activation in tyrosine kinase inhibitor-dependent hepatotoxicity: induction of CYP3A4 enhances the cytotoxicity of lapatinib in HepaRG cells.
Topics: Biotransformation; Cell Line, Tumor; Cell Survival; Cysteine; Cytochrome P-450 CYP3A; Dexamethasone; Glutathione; Hepatocytes; Humans; Lapatinib; Liver; Protein Kinase Inhibitors; Protein-Tyrosine Kinases; Quinazolines; Rifampin | 2014 |
Covalent EGFR inhibitor analysis reveals importance of reversible interactions to potency and mechanisms of drug resistance.
Topics: Antineoplastic Agents; Catalysis; Cell Line, Tumor; Chemistry, Pharmaceutical; Cysteine; Drug Design; Drug Resistance; Enzyme Inhibitors; Enzyme-Linked Immunosorbent Assay; ErbB Receptors; Humans; Inhibitory Concentration 50; Mass Spectrometry; Oxygen; Phosphorylation; Protein Binding; Protein Conformation; Quinazolines; Signal Transduction | 2014 |
Hg(2+) mediated quinazoline ensemble for highly selective recognition of Cysteine.
Topics: Cations, Divalent; Cysteine; Fluorescence; Fluorescent Dyes; Limit of Detection; Mercury; Models, Molecular; Quinazolines; Spectrometry, Fluorescence; Water | 2014 |
Quantum mechanics/molecular mechanics modeling of covalent addition between EGFR-cysteine 797 and N-(4-anilinoquinazolin-6-yl) acrylamide.
Topics: Acrylamides; Aspartic Acid; Catalytic Domain; Cysteine; ErbB Receptors; Models, Molecular; Molecular Dynamics Simulation; Protein Conformation; Quantum Theory; Quinazolines | 2015 |
Inhibition of DHHC20-Mediated EGFR Palmitoylation Creates a Dependence on EGFR Signaling.
Topics: Acyltransferases; Animals; Antineoplastic Agents; Breast Neoplasms; Cell Death; Cell Line, Tumor; Cell Movement; Cell Proliferation; Cysteine; Endocytosis; Epidermal Growth Factor; ErbB Receptors; Gefitinib; GRB2 Adaptor Protein; HEK293 Cells; Humans; Lipoylation; Mass Spectrometry; Mice; Mutation; NIH 3T3 Cells; Protein Conformation; Protein Kinase Inhibitors; Protein Processing, Post-Translational; Protein Transport; Proteolysis; Quinazolines; RNA Interference; Signal Transduction; Structure-Activity Relationship; Transfection | 2016 |
Induced sensitivity to EGFR inhibitors is mediated by palmitoylated cysteine 1025 of EGFR and requires oncogenic Kras.
Topics: Antineoplastic Agents; Apoptosis; Cocarcinogenesis; Cysteine; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; ErbB Receptors; Gefitinib; Humans; Lipoylation; MCF-7 Cells; Membrane Proteins; Mutation; Neoplasms, Experimental; Proto-Oncogene Proteins p21(ras); Quinazolines | 2017 |
Platination of cysteine by an epidermal growth factor receptor kinase-targeted hybrid agent.
Topics: Amino Acid Sequence; Catalytic Domain; Coordination Complexes; Cysteine; ErbB Receptors; Humans; Organoplatinum Compounds; Platinum; Protein Binding; Protein Kinase Inhibitors; Quinazolines | 2018 |
Selective and reversible modification of kinase cysteines with chlorofluoroacetamides.
Topics: Acetamides; Animals; Antineoplastic Agents; Cell Line; Cysteine; ErbB Receptors; Humans; Mice; Mice, Nude; Neoplasms; Phosphotransferases; Protein Kinase Inhibitors; Pyrimidines; Quinazolines; Structure-Activity Relationship; Xenograft Model Antitumor Assays | 2019 |
Discovery of novel quinazoline-based covalent inhibitors of KRAS G12C with various cysteine-targeting warheads as potential anticancer agents.
Topics: Antineoplastic Agents; Cell Proliferation; Cysteine; Dose-Response Relationship, Drug; Drug Discovery; Drug Screening Assays, Antitumor; Enzyme Inhibitors; Humans; Models, Molecular; Molecular Structure; Proto-Oncogene Proteins p21(ras); Quinazolines; Structure-Activity Relationship; Tumor Cells, Cultured | 2021 |
Evodiamine inhibits stemness and metastasis by altering the SOX9-β-catenin axis in non-small-cell lung cancer.
Topics: Alkaloids; Apoptosis; beta Catenin; Cadherins; Carcinoma, Non-Small-Cell Lung; Caspase 3; Cell Line, Tumor; Cell Proliferation; Cysteine; Humans; Lung Neoplasms; Poly(ADP-ribose) Polymerase Inhibitors; Proto-Oncogene Proteins c-bcl-2; Quinazolines; Reactive Oxygen Species; SOX9 Transcription Factor; Vimentin | 2022 |
Evaluation of Rhenium and Technetium-99m Complexes Bearing Quinazoline Derivatives as Potential EGFR Agents.
Topics: Animals; Cell Line; Cysteine; ErbB Receptors; Humans; Mice; Quinazolines; Radiopharmaceuticals; Rhenium; Technetium; Tissue Distribution | 2023 |