cysteine and probenecid

cysteine has been researched along with probenecid in 26 studies

Research

Studies (26)

TimeframeStudies, this research(%)All Research%
pre-199012 (46.15)18.7374
1990's9 (34.62)18.2507
2000's3 (11.54)29.6817
2010's2 (7.69)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Brown, FC; Zawad, JS1
Chakrabarti, S; Côté, MG; Vu, DD1
Hill, BA; Jones, TW; Lau, SS; Monks, TJ1
Chakrabarti, S; Côté, MG; Guo, WX; Malick, MA1
Anders, MW; Sharma, VK; Sheu, SS; Vamvakas, S1
Boogaard, PJ; Commandeur, JN; Mulder, GJ; Nagelkerke, JF; Vermeulen, NP1
Stevens, JL; Zhang, GH1
Brendel, K; Gandolfi, AJ; Stevens, JL; Wolfgang, GH1
Bakke, JE; Brandt, I; Darnerud, PO; Feil, VJ1
Anders, MW; Elfarra, AA; Jakobson, I1
Anders, MW; Lash, LH1
Dekant, W; Henschler, D; Schrenk, D1
Anders, MW; Baggs, RB; Elfarra, AA1
Cafruny, EJ; Cho, KC; Gussin, RZ1
Clarkson, TW; Magos, L1
Johnson, S; Kaung, C; Roboz, J; Yu, TF1
Angiolini, P; Cavuta, M; Cellai, MP; Falsini, S; Novelli, GP1
Dantzler, WH; Evans, KK; Wright, SH1
Fujiyama, J; Hirayama, K; Yasutake, A1
Dantzler, WH; Evans, KK; Groves, CE; North, J; Stevens, JL; Welborn, JR; Wright, SH1
Ishmael, J; Lock, EA1
Cleynhens, BJ; Vanbilloen, HP; Verbruggen, AM1
Leaner, JJ; Mason, RP1
Ahmad, S; Zalups, RK1
Burckhardt, BC; Burckhardt, G; Hagos, Y1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1

Reviews

1 review(s) available for cysteine and probenecid

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Trials

1 trial(s) available for cysteine and probenecid

ArticleYear
Synthesis and biological evaluation of the four isomers of technetium-99m labeled ethylenecysteamine cysteine ((99m)Tc-ECC), the mono-acid derivative of (99m)tc-L,L-ethylenedicysteine.
    Nuclear medicine and biology, 2000, Volume: 27, Issue:2

    Topics: Adult; Animals; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Cysteine; Electrophoresis, Paper; Humans; Isotope Labeling; Kidney; Male; Mice; Organotechnetium Compounds; Papio; Probenecid; Protein Binding; Radioisotope Renography; Radiopharmaceuticals; Renal Agents; Stereoisomerism; Tissue Distribution

2000

Other Studies

24 other study(ies) available for cysteine and probenecid

ArticleYear
A study of norepinephrine metabolism in rat brain using a double label technique.
    Biochemical pharmacology, 1977, Jul-01, Volume: 26, Issue:13

    Topics: Animals; Brain; Cysteine; Male; Norepinephrine; Probenecid; Rats; Sulfur Radioisotopes; Sulfuric Acid Esters; Time Factors; Tritium; Vitamin B 6 Deficiency

1977
Effects of cysteine derivatives of styrene on the transport of p-aminohippurate ion in renal plasma membrane vesicles.
    Archives of toxicology, 1991, Volume: 65, Issue:5

    Topics: Animals; Biological Transport; Cell Membrane; Cysteine; In Vitro Techniques; Kidney; Male; Microvilli; p-Aminohippuric Acid; Probenecid; Rats; Rats, Inbred Strains; Sodium-Potassium-Exchanging ATPase; Styrenes

1991
Nephrotoxicity of 2-bromo-(cystein-S-yl) hydroquinone and 2-bromo-(N-acetyl-L-cystein-S-yl) hydroquinone thioethers.
    Toxicology and applied pharmacology, 1991, Volume: 111, Issue:2

    Topics: Aminooxyacetic Acid; Animals; Cysteine; Hydroquinones; Kidney; Kidney Diseases; Male; Necrosis; Probenecid; Rats; Rats, Inbred Strains

1991
Effect of S-(2-chloroethyl)-DL-cysteine on the transport of p-aminohippurate ion in renal plasma membrane vesicles.
    Archives of biochemistry and biophysics, 1990, Nov-15, Volume: 283, Issue:1

    Topics: Animals; Biological Transport; Cell Membrane; Cysteine; gamma-Glutamyltransferase; Kidney Cortex; Kinetics; Male; Microvilli; p-Aminohippuric Acid; Probenecid; Rats; Rats, Inbred F344; Sodium-Potassium-Exchanging ATPase

1990
Perturbations of intracellular calcium distribution in kidney cells by nephrotoxic haloalkenyl cysteine S-conjugates.
    Molecular pharmacology, 1990, Volume: 38, Issue:4

    Topics: Animals; Calcium; Cell Line; Cysteine; Homeostasis; Homocysteine; Kidney; Mitochondria; Probenecid; Swine

1990
Toxicity of the cysteine-S-conjugates and mercapturic acids of four structurally related difluoroethylenes in isolated proximal tubular cells from rat kidney. Uptake of the conjugates and activation to toxic metabolites.
    Biochemical pharmacology, 1989, Nov-01, Volume: 38, Issue:21

    Topics: Acetylation; Acetylcysteine; Animals; Biological Transport; Chromatography, High Pressure Liquid; Cysteine; Gas Chromatography-Mass Spectrometry; Hydrocarbons, Fluorinated; Inactivation, Metabolic; Kidney Tubules, Proximal; Male; Probenecid; Rats; Rats, Inbred Strains; Subcellular Fractions

1989
Transport and activation of S-(1,2-dichlorovinyl)-L-cysteine and N-acetyl-S-(1,2-dichlorovinyl)-L-cysteine in rat kidney proximal tubules.
    Toxicology and applied pharmacology, 1989, Volume: 100, Issue:1

    Topics: Acetylcysteine; Animals; Biological Transport; Biotransformation; Cysteine; Drug Interactions; In Vitro Techniques; Kidney Tubules, Proximal; Male; Probenecid; Rats; Rats, Inbred Strains; Sulfur Radioisotopes

1989
N-acetyl S-(1,2-dichlorovinyl)-L-cysteine produces a similar toxicity to S-(1,2-dichlorovinyl)-L-cysteine in rabbit renal slices: differential transport and metabolism.
    Toxicology and applied pharmacology, 1989, Volume: 101, Issue:2

    Topics: Acetylation; Aminooxyacetic Acid; Animals; Biological Transport; Cysteine; Dose-Response Relationship, Drug; Hydrocarbons, Halogenated; Kidney Cortex; Kidney Tubules, Proximal; p-Aminohippuric Acid; Potassium; Probenecid; Rabbits

1989
Dichlorovinyl cysteine (DCVC) in the mouse kidney: tissue-binding and toxicity after glutathione depletion and probenecid treatment.
    Archives of toxicology, 1989, Volume: 63, Issue:5

    Topics: Animals; Autoradiography; Cysteine; Female; Glutathione; Kidney; Kidney Diseases; Kidney Tubules; Mice; Mice, Inbred C57BL; Probenecid; Sulfhydryl Compounds

1989
Mechanism of S-(1,2-dichlorovinyl)glutathione-induced nephrotoxicity.
    Biochemical pharmacology, 1986, Jan-15, Volume: 35, Issue:2

    Topics: Aminooxyacetic Acid; Animals; Blood Urea Nitrogen; Carbon-Sulfur Lyases; Cysteine; gamma-Glutamyltransferase; Glutathione; Glycosuria; Isoxazoles; Kidney; Liver; Lyases; Male; Mitochondria; Probenecid; Rats; Rats, Inbred F344; Subcellular Fractions

1986
Uptake of nephrotoxic S-conjugates by isolated rat renal proximal tubular cells.
    The Journal of pharmacology and experimental therapeutics, 1989, Volume: 248, Issue:2

    Topics: Aminooxyacetic Acid; Animals; Biological Transport; Cysteine; Homocysteine; In Vitro Techniques; Kidney Tubules, Proximal; Male; Probenecid; Rats; Rats, Inbred F344; Sodium

1989
Metabolism and excretion of S-conjugates derived from hexachlorobutadiene in the isolated perfused rat kidney.
    Molecular pharmacology, 1988, Volume: 34, Issue:3

    Topics: Acetylation; Animals; Butadienes; Cysteine; Female; Glutathione; Kidney; Perfusion; Probenecid; Rats; Rats, Inbred Strains

1988
Structure-nephrotoxicity relationships of S-(2-chloroethyl)-DL-cysteine and analogs: role for an episulfonium ion.
    The Journal of pharmacology and experimental therapeutics, 1985, Volume: 233, Issue:2

    Topics: Acute Kidney Injury; Alanine Transaminase; Animals; Blood Urea Nitrogen; Cysteine; Glycosuria; Ions; Kidney Cortex; Kidney Tubular Necrosis, Acute; Male; Onium Compounds; Probenecid; Rats; Structure-Activity Relationship; Sulfonium Compounds; Time Factors

1985
The pharmacology of mercurial diuretics.
    Annals of the New York Academy of Sciences, 1966, Nov-22, Volume: 139, Issue:2

    Topics: Albumins; Aminohippuric Acids; Animals; Chlormerodrin; Cysteine; Dogs; Glomerular Filtration Rate; Kidney; Mercury; Mercury Isotopes; Natriuresis; Organomercury Compounds; Probenecid; Rats

1966
Effect of 2,4-dinitrophenol and other metabolic inhibitors on the renal deposition and excretion of mercury.
    Biochemical pharmacology, 1970, Volume: 19, Issue:12

    Topics: Animals; Chlorides; Creatinine; Cysteine; Dinitrophenols; Female; Fluorides; Fluoroacetates; Kidney; Liver; Malonates; Mercury; Mercury Isotopes; Potassium; Probenecid; Quaternary Ammonium Compounds; Rats; Sodium; Time Factors; Urea

1970
Studies on the metabolism of D-penicillamine and its interaction with probenecid in cystinuria and rheumatoid arthritis.
    The Journal of rheumatology, 1984, Volume: 11, Issue:4

    Topics: Arthritis, Rheumatoid; Cysteine; Cystinuria; Drug Therapy, Combination; Female; Humans; Male; Penicillamine; Pilot Projects; Probenecid; Time Factors

1984
[Reduced glutathione and L-cysteine in endotoxic shock in the rat].
    Minerva anestesiologica, 1994, Volume: 60, Issue:9

    Topics: Animals; Cysteine; Endotoxins; Ethanol; Glutathione; Lipopolysaccharides; Male; Oxidation-Reduction; Probenecid; Rats; Rats, Wistar; Shock, Septic

1994
Kinetics of interactions of para-aminohippurate, probenecid, cysteine conjugates and N-acetyl cysteine conjugates with basolateral organic anion transporter in isolated rabbit proximal renal tubules.
    The Journal of pharmacology and experimental therapeutics, 1995, Volume: 272, Issue:2

    Topics: Acetylcysteine; Animals; Anion Transport Proteins; Carrier Proteins; Cysteine; In Vitro Techniques; Kidney Tubules, Proximal; Mercuric Chloride; p-Aminohippuric Acid; Probenecid; Rabbits

1995
Mechanism of methylmercury efflux from cultured astrocytes.
    Biochemical pharmacology, 1994, Apr-29, Volume: 47, Issue:9

    Topics: Animals; Astrocytes; Buthionine Sulfoximine; Cells, Cultured; Cysteine; Glutathione; Methionine Sulfoximine; Methylmercury Compounds; Probenecid; Pyrrolidonecarboxylic Acid; Rats; Thiazoles; Thiazolidines

1994
Relation of cysteine conjugate nephrotoxicity to transport by the basolateral organic anion transport system in isolated S2 segments of rabbit proximal renal tubules.
    The Journal of pharmacology and experimental therapeutics, 1998, Volume: 286, Issue:1

    Topics: Animals; Anion Transport Proteins; Biological Transport; Carrier Proteins; Cysteine; In Vitro Techniques; Kidney Tubules, Proximal; Probenecid; Rabbits; Rubidium Radioisotopes

1998
The nephrotoxicity and hepatotoxicity of 1,1,2,2-tetrafluoroethyl-L-cysteine in the rat.
    Archives of toxicology, 1998, Volume: 72, Issue:6

    Topics: Acetylcysteine; Aminooxyacetic Acid; Animals; Butadienes; Cysteine; Dose-Response Relationship, Drug; Female; Hydrocarbons, Fluorinated; Ion Transport; Kidney Diseases; Male; Probenecid; Rats; Renal Agents

1998
Methylmercury accumulation and fluxes across the intestine of channel catfish, Ictalurus punctatus.
    Comparative biochemistry and physiology. Toxicology & pharmacology : CBP, 2002, Volume: 132, Issue:2

    Topics: Animals; Biological Transport, Active; Catfishes; Cysteine; Intestinal Mucosa; Intestines; Metals; Methionine; Methylmercury Compounds; Ouabain; Probenecid; Selenium; Temperature; Tissue Distribution; Water Pollutants, Chemical

2002
Handling of cysteine S-conjugates of methylmercury in MDCK cells expressing human OAT1.
    Kidney international, 2005, Volume: 68, Issue:4

    Topics: Animals; Biological Transport; Cell Line; Cell Survival; Cysteine; Dicarboxylic Acids; Dogs; Dose-Response Relationship, Drug; Epithelial Cells; Glutarates; Humans; Kidney; Leucine; Methylmercury Compounds; Organic Anion Transport Protein 1; p-Aminohippuric Acid; Probenecid; Temperature; Transfection; Tritium; Uricosuric Agents

2005
Human organic anion transporter OAT1 is not responsible for glutathione transport but mediates transport of glutamate derivatives.
    American journal of physiology. Renal physiology, 2013, Feb-15, Volume: 304, Issue:4

    Topics: Aminohippuric Acids; Aspartic Acid; Biological Transport; Cysteine; Dipeptides; Estrone; Glutamates; Glutathione; Glycine; HEK293 Cells; Humans; Kidney; Organic Anion Transport Protein 1; Organic Anion Transporters, Sodium-Independent; Probenecid; Transfection; Uricosuric Agents

2013