cysteine has been researched along with phenobarbital in 39 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 31 (79.49) | 18.7374 |
| 1990's | 4 (10.26) | 18.2507 |
| 2000's | 3 (7.69) | 29.6817 |
| 2010's | 1 (2.56) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Labuc, GE; Madsen, NP | 1 |
| Artigou, JY; Benhamou, JP; Descatoire, V; Pessayre, D; Wandscheer, JC | 1 |
| Moldéus, P; Orrenius, S; Thor, H | 1 |
| Dahms, R; Gurtoo, HL; Hipkens, J; Vaught, JB | 1 |
| Krishna, G; Pohl, LR | 1 |
| Moldéus, P | 1 |
| Hart, FE; Willson, RA | 1 |
| David, JC | 1 |
| Clarkson, TW; Magos, L | 1 |
| Day, PA; McLean, AE | 1 |
| Holscher, M; Mgbodile, MU; Neal, RA | 1 |
| Gut, I; Holecek, V; Kopecký, J; Nerudová, J | 1 |
| Docks, EL; Krishna, G | 1 |
| Giri, SN; Siegel, DM | 1 |
| Chambers, MA; Gelboin, HV; Gerber, N; Hilliard, JB; Mays, DC; Park, SS; Wong, DD | 1 |
| Armstrong, GR; Beales, D; McLean, AE | 1 |
| Atkins, LM; Fody, EP; Gale, GR; Smith, AB; Walker, EM | 1 |
| Donelli, MG; Garattini, S; Rosso, R | 1 |
| Josephs, JA; Magazino, J; Parker, CM; Sprince, H | 1 |
| Garner, RC; Wright, CM | 1 |
| Magos, L; Osawa, M | 1 |
| Gillette, JR; Jollow, DJ; Mitchell, JR; Zampaglione, N | 1 |
| Bray, TM; Janzen, EG; Kubow, S | 1 |
| Black, SD; Coon, MJ; Fujita, VS; Koop, DR; Tarr, GE | 1 |
| Baillie, TA; Dahlin, DC; Nelson, SD; Streeter, AJ | 1 |
| Clark, JD; Hatch, RC; Jain, AV; Weiss, R | 2 |
| Ballatori, N; Clarkson, TW | 1 |
| Grabowski, PS; Maggs, JL; Park, BK | 1 |
| Black, SD; Coon, MJ; Tarr, GE | 1 |
| Anders, MW; Stevens, JL | 2 |
| Berg, IE; Chaturvedi, AK; Rao, NG | 1 |
| Gremmels-Gehrmann, JF; Horbach, GJ; van 't Klooster, GA; van Miert, AS; Zeilmaker, WM | 1 |
| Cai, J; Horie, T; Kaplowitz, N; Kuhlenkamp, J; Lu, SC; Sun, WM; Takenaka, O; Takikawa, H; Yi, J | 1 |
| Fukushima, S; Otani, S; Takada, N; Vijayaraghavan, M; Wanibuchi, H; Yamamoto, S; Yano, Y | 1 |
| Altuntas, TG; Kharasch, ED; Liggitt, HD; Schroeder, JL; Sheffels, P | 1 |
| Apeland, T; Frøyland, ES; Kristensen, O; Mansoor, MA; Strandjord, RE | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
1 review(s) available for cysteine and phenobarbital
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
38 other study(ies) available for cysteine and phenobarbital
| Article | Year |
|---|---|
Inhibition by 3'-methyl-4-dimethylamino-azobenzene of in vitro cell-free protein synthesis: possible involvement of an electrophilic metabolite.
Topics: Aminopyrine N-Demethylase; Aniline Hydroxylase; Animals; Cell-Free System; Cysteine; Depression, Chemical; Glutathione; In Vitro Techniques; Leucine; Liver; Male; Methyldimethylaminoazobenzene; NADP; Oxidoreductases; p-Dimethylaminoazobenzene; Phenobarbital; Polyethylene Glycols; Protein Biosynthesis; Rats | 1977 |
Formation and inactivation of a chemically reactive metabolite of vinyl chloride.
Topics: Animals; Cysteine; Cytochrome P-450 Enzyme System; DDT; Epoxide Hydrolases; Epoxy Compounds; Glutathione; Hydrocarbons, Chlorinated; Male; Microsomes, Liver; NADP; Phenobarbital; Proadifen; Protein Binding; Rats; Vinyl Chloride; Vinyl Compounds | 1979 |
Metabolic activation and hepatotoxicity. Effect of cysteine, N-acetylcysteine, and methionine on glutathione biosynthesis and bromobenzene toxicity in isolated rat hepatocytes.
Topics: Acetylcysteine; Animals; Biotransformation; Bromobenzenes; Cysteine; Glutathione; In Vitro Techniques; Kinetics; Liver; Male; Maleates; Methionine; Microsomes, Liver; Phenobarbital; Rats | 1979 |
Studies on the binding of [3H-chloroethyl]-cyclophosphamide and 14[C-4] -cyclophosphamide to hepatic microsomes and native calf thymus DNA.
Topics: Animals; Binding Sites; Cattle; Cyclophosphamide; Cysteine; DNA; Glutathione; Male; Methylcholanthrene; Microsomes, Liver; Phenobarbital; Protein Binding; Rats; Semicarbazides; Thymus Gland | 1978 |
Deuterium isotope effect in bioactivation and hepatotoxicity of chloroform.
Topics: Alanine Transaminase; Animals; Chemical and Drug Induced Liver Injury; Chloroform; Cysteine; Cytochrome P-450 Enzyme System; Deuterium; Male; Microsomes, Liver; Phenobarbital; Rats; Thiazoles | 1978 |
Paracetamol metabolism and toxicity in isolated hepatocytes from rat and mouse.
Topics: Acetaminophen; Acetylcysteine; Animals; Cysteine; Glucuronates; Glutathione; In Vitro Techniques; Liver; Male; Mice; Phenobarbital; Rats; Sulfates; Time Factors | 1978 |
In vitro spectral alteration of hepatic cytochrome P-450 by experimental drug injury.
Topics: Acetaminophen; Animals; Buffers; Chemical and Drug Induced Liver Injury; Cysteamine; Cysteine; Cytochrome P-450 Enzyme System; Dimethyl Sulfoxide; Enzyme Induction; Glutathione; In Vitro Techniques; Liver Diseases; Male; Methionine; Microsomes, Liver; Phenobarbital; Rats; Solvents | 1977 |
Evidence for the possible formation of a toxic tyrosine metabolite by the liver microsomal drug metabolizing system.
Topics: Animals; Benserazide; Biotransformation; Cobalt; Cysteine; Glutathione; Humans; Male; Maleates; Methylcholanthrene; Mice; Microsomes, Liver; Phenobarbital; Proadifen; Tyrosine | 1976 |
The effect of oral doses of a polythiol resin on the excretion of methylmercury in mice treated with cysteine, D-penicillamine or phenobarbitone.
Topics: Animals; Cysteine; Feces; Kinetics; Male; Mercury; Methylmercury Compounds; Mice; Penicillamine; Phenobarbital; Resins, Plant; Sulfhydryl Compounds; Time Factors | 1976 |
The effect of diet on the toxicity of paracetamol and the safety of paracetamol-methionine mixtures.
Topics: Acetaminophen; Animals; Body Weight; Caseins; Chemical and Drug Induced Liver Injury; Cysteine; Cytochrome P-450 Enzyme System; Dietary Proteins; Drug Combinations; Fasting; Glutathione; Lethal Dose 50; Liver; Male; Methionine; Necrosis; Oils; Phenobarbital; Rats; Selenium; Yeast, Dried | 1975 |
A possible protective role for reduced glutathione in aflatoxin B1 toxicity: effect of pretreatment of rats with phenobarbital and 3-methylcholanthrene on aflatoxin toxicity.
Topics: Aflatoxins; Animals; Benzphetamine; Body Weight; Chemical and Drug Induced Liver Injury; Cysteine; Cytochrome P-450 Enzyme System; Drug Interactions; Glutathione; Liver; Male; Maleates; Methylcholanthrene; Microsomes, Liver; Mixed Function Oxygenases; Necrosis; Phenobarbital; Rats | 1975 |
Acrylonitrile biotransformation in rats, mice, and chinese hamsters as influenced by the route of administration and by phenobarbital, SKF 525-A, cysteine, dimercaprol, or thiosulfate.
Topics: Administration, Oral; Animals; Biotransformation; Cricetinae; Cysteine; Dimercaprol; Female; Injections, Intraperitoneal; Injections, Intravenous; Injections, Subcutaneous; Mice; Nitriles; Nitrites; Phenobarbital; Proadifen; Rats; Thiocyanates; Thiosulfates; Vinyl Compounds | 1975 |
The role of glutathione in chloroform-induced hepatotoxicity.
Topics: Acetone; Alkanes; Animals; Carbon Tetrachloride; Chloroform; Cysteamine; Cysteine; Dose-Response Relationship, Drug; Glutathione; Kidney; Lens, Crystalline; Liver; Male; Maleates; Methylcholanthrene; Phenobarbital; Propranolol; Rats | 1976 |
Characterization of covalent binding of [14C]-2-chloro-4-acetotoluidide to microsomes of starling liver and kidney.
Topics: Animals; Benzoflavones; Birds; Cysteine; Cytochrome P-450 Enzyme Inhibitors; Glutathione; In Vitro Techniques; Kidney; Kinetics; Male; Methylcholanthrene; Microsomes; Microsomes, Liver; Mixed Function Oxygenases; Phenobarbital; Proadifen; Protein Binding; Sulfhydryl Compounds; Toluidines | 1991 |
Bioactivation of 8-methoxypsoralen and irreversible inactivation of cytochrome P-450 in mouse liver microsomes: modification by monoclonal antibodies, inhibition of drug metabolism and distribution of covalent adducts.
Topics: 7-Alkoxycoumarin O-Dealkylase; Animals; Antibodies, Monoclonal; Benzoflavones; beta-Naphthoflavone; Binding Sites; Cells, Cultured; Cysteine; Cytochrome P-450 Enzyme System; Flavonoids; Lysine; Male; Methoxsalen; Mice; Microsomes, Liver; Phenobarbital | 1990 |
Effect of D- or L-methionine and cysteine on the growth inhibitory effects of feeding 1% paracetamol to rats.
Topics: Acetaminophen; Animals; Chemical and Drug Induced Liver Injury; Cysteine; Glutathione; Growth; Methionine; Phenobarbital; Rats; Sulfates | 1989 |
Effects of acetaminophen on cadmium metabolism in mice.
Topics: Acetaminophen; Animals; Body Burden; Cadmium; Chromatography, Gel; Cysteine; Feces; Kidney; Liver; Male; Metallothionein; Mice; Phenobarbital | 1986 |
On the neurotoxic effects induced by alkylating agents.
Topics: Alanine; Animals; Anti-Bacterial Agents; Antimetabolites; Azaserine; Behavior, Animal; Central Nervous System; Chlorambucil; Cyclophosphamide; Cysteine; Drug Antagonism; Glycine; Male; Mannitol; Mechlorethamine; Melphalan; Nitrogen Mustard Compounds; Phenobarbital; Phenytoin; Rats; Seizures; Spasm; Thiourea; Triethylenemelamine; Tryptophan | 1966 |
Convulsant activity of homocysteine and other short-chain mercaptoacids: protection therefrom.
Topics: Animals; Betaine; Central Nervous System Stimulants; Cysteine; Glycine; Homocysteine; Male; Methionine; Phenobarbital; Pyridoxine; Rats; Serine | 1969 |
Induction of mutations in DNA-repair deficient bacteria by a liver microsomal metabolite of aflatoxin B1.
Topics: Aflatoxins; Animals; Benzopyrenes; Cysteine; Dimercaprol; DNA Repair; DNA, Bacterial; Escherichia coli; Liver; Male; Methionine; Methylcholanthrene; Microsomes, Liver; Mutation; Oxidoreductases; Phenobarbital; Rats; Salmonella typhimurium; Ultraviolet Rays | 1973 |
Proceedings: Biliary excretion of methylmercury in male rats.
Topics: Animals; Bile; Cysteine; Male; Methylmercury Compounds; Phenobarbital; Rats; Stimulation, Chemical | 1973 |
Bromobenzene-induced liver necrosis. Protective role of glutathione and evidence for 3,4-bromobenzene oxide as the hepatotoxic metabolite.
Topics: Animals; Benzene Derivatives; Biotransformation; Carbon Radioisotopes; Chemical and Drug Induced Liver Injury; Cysteine; Depression, Chemical; Dose-Response Relationship, Drug; Drug Interactions; Glutathione; Hydrocarbons, Brominated; In Vitro Techniques; Liver; Male; Maleates; Microsomes, Liver; Necrosis; Oxidation-Reduction; Phenobarbital; Proadifen; Protein Binding; Rats | 1974 |
Spin-trapping of free radicals formed during in vitro and in vivo metabolism of 3-methylindole.
Topics: Animals; Cysteine; Cytochrome P-450 Enzyme System; Electron Spin Resonance Spectroscopy; Free Radicals; Glutathione; Goats; Indoles; Kinetics; Lung; Male; Microsomes; Mixed Function Oxygenases; Phenobarbital; Skatole; Ultraviolet Rays | 1984 |
On the amino acid sequence of cytochrome P-450 isozyme 4 from rabbit liver microsomes.
Topics: Amino Acid Sequence; Animals; Cysteine; Cytochrome P-450 Enzyme System; Isoenzymes; Microsomes, Liver; Peptide Fragments; Phenobarbital; Rabbits; Rats | 1984 |
The covalent binding of acetaminophen to protein. Evidence for cysteine residues as major sites of arylation in vitro.
Topics: Acetaminophen; Amino Acids; Animals; Benzoquinones; Caseins; Cysteine; Glutathione; Imines; Male; Mice; Mice, Inbred BALB C; Microsomes, Liver; NADP; Phenobarbital; Proteins; Serum Albumin, Bovine | 1984 |
Effect of enzyme inducers and inhibitors and glutathione precursor and depleter on induced acute aflatoxicosis in rabbits.
Topics: Acute Disease; Aflatoxin B1; Aflatoxins; Animals; Benzoflavones; Carcinogens; Chlorides; Cobalt; Cysteine; Enzyme Induction; Enzyme Inhibitors; Glutathione; Goats; Liver; Male; Maleates; Microsomes, Liver; Phenobarbital; Phenylbutazone; Piperonyl Butoxide; Rabbits; Rats; Stanozolol | 1982 |
Biliary transport of glutathione and methylmercury.
Topics: Animals; Bile; Cysteine; Female; Glutathione; Male; Methylmercury Compounds; Penicillamine; Phenobarbital; Rats; Rats, Inbred Strains; Sulfhydryl Compounds | 1983 |
Drug-protein conjugates--II. An investigation of the irreversible binding and metabolism of 17 alpha-ethinyl estradiol in vivo.
Topics: Animals; Bile; Cysteine; Enzyme Induction; Ethinyl Estradiol; Male; Microsomes, Liver; Mixed Function Oxygenases; Phenobarbital; Protein Binding; Rats; Rats, Inbred Strains | 1983 |
Toxicologic study of carboxyatractyloside (active principle in cocklebur--Xanthium strumarium) in rats treated with enzyme inducers and inhibitors and glutathione precursor and depletor.
Topics: Animals; Atractyloside; Benzoflavones; beta-Naphthoflavone; Cobalt; Cysteine; Glycosides; Kidney Tubules; Lethal Dose 50; Liver; Male; Maleates; Phenobarbital; Phenylbutazone; Piperonyl Butoxide; Plants, Toxic; Rats; Rats, Inbred Strains; Stanozolol | 1982 |
Structural features of isozyme 2 of liver microsomal cytochrome P-450. Identification of a highly conserved cysteine-containing peptide.
Topics: Amino Acid Sequence; Animals; Cysteine; Cytochrome P-450 Enzyme System; Male; Microsomes, Liver; Peptide Fragments; Phenobarbital; Rabbits; Rats; Species Specificity | 1982 |
Effect of cysteine, diethyl maleate, and phenobarbital treatments on the hepatotoxicity of [1H]chloroform.
Topics: Alanine Transaminase; Animals; Biotransformation; Chloroform; Cysteine; Liver; Male; Maleates; Phenobarbital; Phosgene; Rats; Rats, Inbred Strains | 1981 |
Metabolism of haloforms to carbon monoxide. IV. studies on the reaction mechanism in vivo.
Topics: Animals; Carbon Monoxide; Carcinogens; Chloroform; Cysteine; Deuterium; Hydrocarbons, Brominated; Male; Maleates; Phenobarbital; Pyrrolidonecarboxylic Acid; Rats; Rats, Inbred Strains; Thiazoles; Thiazolidines; Trihalomethanes | 1981 |
The role of hepatic microsomal enzymes in the modulation of phencyclidine-induced toxicity.
Topics: Animals; Body Weight; Cysteine; Eating; Lethal Dose 50; Liver; Male; Maleates; Methylcholanthrene; Mice; Microsomes, Liver; Pentobarbital; Phencyclidine; Phenobarbital; Proadifen | 1981 |
cDNA and deduced amino acid sequence of a dwarf goat liver cytochrome P450 fragment belonging to the CYP2C gene subfamily.
Topics: Amino Acid Sequence; Animals; Aryl Hydrocarbon Hydroxylases; Blotting, Northern; Cysteine; Cytochrome P-450 Enzyme System; DNA, Complementary; Goats; Humans; Liver; Molecular Sequence Data; Multigene Family; Phenobarbital; Rabbits; RNA; Sequence Homology, Amino Acid; Sequence Homology, Nucleic Acid; Steroid 16-alpha-Hydroxylase; Steroid Hydroxylases | 1994 |
Alterations in glutathione homeostasis in mutant Eisai hyperbilirubinemic rats.
Topics: Analysis of Variance; Animals; Bile; Body Weight; Cysteine; Female; Glutamate-Cysteine Ligase; Glutathione; Homeostasis; Hyperbilirubinemia; Intestinal Mucosa; Intestine, Small; Kidney; Liver; Male; Organ Size; Phenobarbital; Rats; Rats, Mutant Strains; Rats, Sprague-Dawley; Reference Values; RNA, Messenger; Transcription, Genetic | 1996 |
Inhibitory effects of S-methylcysteine and cysteine on the promoting potential of sodium phenobarbital on rat liver carcinogenesis.
Topics: Animals; Carcinogens; Cysteine; Disease Models, Animal; Glutathione Transferase; Immunohistochemistry; Liver Neoplasms; Male; Ornithine Decarboxylase; Phenobarbital; Proliferating Cell Nuclear Antigen; Rats; Rats, Inbred F344 | 2000 |
Role of cytochrome P4503A in cysteine S-conjugates sulfoxidation and the nephrotoxicity of the sevoflurane degradation product fluoromethyl-2,2-difluoro-1-(trifluoromethyl)vinyl ether (compound A) in rats.
Topics: Anesthetics, Inhalation; Animals; Aryl Hydrocarbon Hydroxylases; Cysteine; Cytochrome P-450 CYP3A; Dexamethasone; Ethers; Hydrocarbons, Fluorinated; Kidney Diseases; Lyases; Male; Methyl Ethers; Oxidoreductases, N-Demethylating; Phenobarbital; Propionates; Rats; Rats, Inbred F344; Sevoflurane; Sulfoxides; Troleandomycin | 2004 |
Drug-induced pertubation of the aminothiol redox-status in patients with epilepsy: improvement by B-vitamins.
Topics: Adult; Anticonvulsants; Carbamazepine; Case-Control Studies; Cysteine; Dipeptides; Drug Evaluation; Epilepsy; Female; Folic Acid; Humans; Hyperhomocysteinemia; Liver; Male; Methionine; Oxidation-Reduction; Phenobarbital; Phenytoin; Primidone; Pyridoxine; Riboflavin; Valproic Acid; Vitamin B Deficiency | 2008 |