cysteine and paclitaxel

cysteine has been researched along with paclitaxel in 35 studies

Research

Studies (35)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (5.71)18.2507
2000's13 (37.14)29.6817
2010's16 (45.71)24.3611
2020's4 (11.43)2.80

Authors

AuthorsStudies
Hatsuzawa, K; Himeno, M; Nakayama, K; Tagaya, M; Tani, K; Yamaguchi, T1
Beckmann, H; Chou, TC; Frankmoelle, WP; Jaen, JC; Learned, RM; Medina, JC; Narbut, MR; Rosen, T; Santha, E; Shan, B; Stott, D; Timmermans, PB; Wu, P1
Abbruzzes, J; Azhdarinia, A; Bryant, JL; Fogler, WE; Herbst, R; Kalimi, SK; Kim, EE; Kim, KD; Ozaki, K; Podoloff, DA; Roach, JS; Schechter, NR; Wu, P; Yang, DJ; Yu, DF1
Nathan, C; Shen, C1
Hausheer, F; Murphy, M; Pendyala, L; Schwartz, G; Smith, P; Zdanowicz, J1
Callaghan, R; Kerr, ID; McMahon, R; Rothnie, A; Storm, J; Taylor, A1
Bernhardt, G; Buschauer, A; Gartner, M; Giannis, A; Gross, D; Müller, C; Sarli, V1
Al-Humadi, NH; Hu, S; Ma, JK; Yin, XJ; Zhao, H1
Kropf, DL; Peters, NT1
Hustoft, HK; Indorato, RL; Jungblut, PR; Kozielski, F; Saoudi, Y; Skoufias, DA; Strozynski, M; Thiede, B1
Bernkop-Schnürch, A; Föger, F; Huck, C; Malaivijitnond, S; Wannaprasert, T; Werle, M1
Artime, N; Burlingame, AL; Cabal-Hierro, L; Casado, P; Del Valle, E; Lazo, PS; Prado, MA; Ramos, S; Rupérez, P; Zuazua-Villar, P1
Khong, A; McHardy, LM; Riffell, JL; Roberge, M; Zimmerman, C1
Carrico, ZM; Francis, MB; Hsiao, SC; Wu, W1
Artime, N; Cabal-Hierro, L; Calvo, E; Casado, P; Fernandez-Garcia, B; Lazo, PS; López, JA; Prado, MA; Ramos, S; Ugarte-Gil, LJ1
Jiang, X; Li, L; Liu, J; Zhuo, R1
Chin, YW; Choi, YH; Han, SY; Lee, YK1
Ge, L; Jiang, L; Liu, J; Liu, Q; Tang, Y; Xu, Y; Zheng, C; Zhu, J1
Benita, S; Borlak, J; Karra, N; Nassar, T; Ripin, AN; Schwob, O1
Ge, J; Li, LB; Li, N; Li, Y; Zhao, Y1
Ramanathan, K; Verma, K1
Fan, X; Li, L; Xu, W; Zhao, Y1
Knipp, G; Kulczar, C; Lavan, M; Mehtala, JG; Wei, A1
Gagat, M; Grzanka, A; Grzanka, D; Hałas-Wiśniewska, M; Izdebska, M1
Chen, ZG; Majumdar, D; Rahman, MA; Shin, DM1
Prabhune, M; Rehfeldt, F; Schmidt, CF; von Roden, K1
Maesawa, C; Nishiya, M; Shibazaki, M; Yasuhira, S1
Bolte, S; Buffin, E; Cladière, D; El Yakoubi, W; Leontiou, I; Vallot, A; Wassmann, K1
Baker, JR; Caspersen, MB; Chudasama, V; Howard, KA; Karu, K; Nicholls, K; Skrivergaard, S; Wall, A1
Du, X; Li, J; Ma, J; Wang, G; Xu, L; Yin, S; Yu, H1
Martín Del Valle, EM; Nieto, C; Pérez-Esteban, P; Rodríguez, V; Vega, MA1
Chen, J; Chen, M; Huang, X; Liu, J; Shangguan, M; Wang, T; Wu, S; Yang, Z; Zhang, C; Zhao, S1
He, C; Jiang, L; Meng, Y; Tong, T; Wang, K; Wang, L; Wu, J; Xu, X; You, X; Yu, Y; Zhang, W; Zhao, M1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1

Reviews

1 review(s) available for cysteine and paclitaxel

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Other Studies

34 other study(ies) available for cysteine and paclitaxel

ArticleYear
ADP-ribosylation factor-1 is sensitive to N-ethylmaleimide.
    Journal of biochemistry, 1998, Dec-01, Volume: 124, Issue:6

    Topics: Adaptor Protein Complex gamma Subunits; ADP-Ribosylation Factor 1; ADP-Ribosylation Factors; Animals; Cattle; Cells, Cultured; Coatomer Protein; Cysteine; Cytosol; Ethylmaleimide; Golgi Apparatus; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Intracellular Membranes; Kidney; Membrane Proteins; Microtubule-Associated Proteins; Paclitaxel; Rats

1998
Selective, covalent modification of beta-tubulin residue Cys-239 by T138067, an antitumor agent with in vivo efficacy against multidrug-resistant tumors.
    Proceedings of the National Academy of Sciences of the United States of America, 1999, May-11, Volume: 96, Issue:10

    Topics: Animals; Antineoplastic Agents; Apoptosis; Cell Cycle; Cysteine; Cytoskeleton; Drug Resistance, Multiple; Humans; Leukemia, Lymphoid; Mice; Mice, Nude; Microtubules; Molecular Structure; Neoplasm Transplantation; Paclitaxel; Protein Binding; Sulfonamides; Tubulin; Tumor Cells, Cultured; Vinblastine

1999
Cutaneous drug reaction case reports: from the world literature.
    American journal of clinical dermatology, 2001, Volume: 2, Issue:4

    Topics: Adolescent; Adverse Drug Reaction Reporting Systems; Aged; Amlodipine; Anti-Bacterial Agents; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Anticoagulants; Anticonvulsants; Antihypertensive Agents; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Antirheumatic Agents; BCG Vaccine; Cefotetan; Cephamycins; Contrast Media; Cysteine; Dapsone; Diltiazem; Dipyrone; Docetaxel; Drug Eruptions; Echinacea; Enoxaparin; Female; Fructose; Glucans; Glucose; Gold Sodium Thiomalate; Humans; Ibuprofen; Icodextrin; Ioxaglic Acid; Male; Middle Aged; Minocycline; Paclitaxel; Pregnancy; Solvents; Taxoids; Topiramate; Triamcinolone; Trichloroethylene

2001
Assessment of antiangiogenic effect using 99mTc-EC-endostatin.
    Cancer biotherapy & radiopharmaceuticals, 2002, Volume: 17, Issue:2

    Topics: Angiogenesis Inhibitors; Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Collagen; Cysteine; Endostatins; Endothelial Growth Factors; Female; Fibroblast Growth Factor 2; In Situ Nick-End Labeling; Intercellular Signaling Peptides and Proteins; Interleukin-8; Lymphokines; Mammary Neoplasms, Experimental; Neovascularization, Pathologic; Paclitaxel; Peptide Fragments; Radionuclide Imaging; Rats; Rats, Inbred F344; Technetium; Tumor Cells, Cultured; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors

2002
Nonredundant antioxidant defense by multiple two-cysteine peroxiredoxins in human prostate cancer cells.
    Molecular medicine (Cambridge, Mass.), 2002, Volume: 8, Issue:2

    Topics: Animals; Antibody Specificity; Antineoplastic Agents; Antioxidants; Cysteine; Doxorubicin; Etoposide; Humans; Hydrogen Peroxide; Immune Sera; Male; Mice; Oxidative Stress; Paclitaxel; Peroxidases; Peroxiredoxin III; Peroxiredoxins; Prostatic Neoplasms; Protein Isoforms; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha

2002
Modulation of plasma thiols and mixed disulfides by BNP7787 in patients receiving paclitaxel/cisplatin therapy.
    Cancer chemotherapy and pharmacology, 2003, Volume: 51, Issue:5

    Topics: Antineoplastic Combined Chemotherapy Protocols; Chromatography, High Pressure Liquid; Cisplatin; Cysteine; Disulfides; Glutathione; Half-Life; Humans; Infusions, Intravenous; Kinetics; Mesna; Neoplasms; Paclitaxel; Sulfhydryl Compounds

2003
The coupling mechanism of P-glycoprotein involves residue L339 in the sixth membrane spanning segment.
    FEBS letters, 2005, Jul-18, Volume: 579, Issue:18

    Topics: Adenosine Triphosphatases; Adenosine Triphosphate; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Baculoviridae; Binding Sites; Catalysis; Cell Line; Cell Membrane; Coumarins; Cysteine; Hydrolysis; Insecta; Kinetics; Linear Models; Mutagenesis, Site-Directed; Nicardipine; Paclitaxel; Protein Binding; Protein Conformation; Protein Isoforms; Protein Structure, Tertiary; Protein Transport; Quinolines; Recombinant Proteins; Sulfhydryl Compounds; Time Factors; Vinblastine

2005
Inhibitors of kinesin Eg5: antiproliferative activity of monastrol analogues against human glioblastoma cells.
    Cancer chemotherapy and pharmacology, 2007, Volume: 59, Issue:2

    Topics: Acridines; Antineoplastic Agents, Phytogenic; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cell Line, Tumor; Cell Proliferation; Cell Survival; Cysteine; Dose-Response Relationship, Drug; Flow Cytometry; Fluoresceins; Glioblastoma; Humans; Insecticides; Kinesins; Molecular Structure; Paclitaxel; Pyrimidines; Quinazolines; Rotenone; Spindle Apparatus; Tetrahydroisoquinolines; Thiones; Time Factors; Tubulin; Tubulin Modulators; Vinblastine

2007
Silica-induced apoptosis in alveolar macrophages: evidence of in vivo thiol depletion and the activation of mitochondrial pathway.
    Journal of toxicology and environmental health. Part A, 2006, Volume: 69, Issue:13

    Topics: Acetylcysteine; Alkaloids; Animals; Anti-Inflammatory Agents; Apoptosis; Apoptosis Regulatory Proteins; Benzylisoquinolines; Caspase 3; Caspases; Cysteine; Cytochromes c; Disease Models, Animal; Glutathione; Inflammation Mediators; Macrophages, Alveolar; Male; Membrane Potentials; Microscopy, Confocal; Mitochondria; Oxidative Stress; Paclitaxel; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Silicon Dioxide; Sulfhydryl Compounds; Tumor Necrosis Factor-alpha

2006
Kinesin-5 motors are required for organization of spindle microtubules in Silvetia compressa zygotes.
    BMC plant biology, 2006, Aug-31, Volume: 6

    Topics: Cell Polarity; Cysteine; Cytokinesis; Dinitrobenzenes; Kinesins; Microtubules; Mitosis; Molecular Motor Proteins; Paclitaxel; Phaeophyceae; Pyrimidines; Spindle Apparatus; Sulfanilamides; Thiones; Zygote

2006
Proteome analysis of apoptosis signaling by S-trityl-L-cysteine, a potent reversible inhibitor of human mitotic kinesin Eg5.
    Proteomics, 2008, Volume: 8, Issue:2

    Topics: Apoptosis; Cysteine; HeLa Cells; Humans; Kinesins; Mitosis; Paclitaxel; Proteome; Signal Transduction

2008
Effect of a thiolated polymer on oral paclitaxel absorption and tumor growth in rats.
    Journal of drug targeting, 2008, Volume: 16, Issue:2

    Topics: Acrylic Resins; Administration, Oral; Animals; Antineoplastic Agents, Phytogenic; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Availability; Cysteine; Female; Male; Mammary Neoplasms, Experimental; Paclitaxel; Rats; Rats, Sprague-Dawley; Solubility

2008
Microtubule interfering agents and KSP inhibitors induce the phosphorylation of the nuclear protein p54(nrb), an event linked to G2/M arrest.
    Journal of proteomics, 2009, Jan-30, Volume: 71, Issue:6

    Topics: Antineoplastic Agents, Phytogenic; Cell Line; Cisplatin; Cysteine; DNA-Binding Proteins; Electrophoresis, Gel, Two-Dimensional; G2 Phase; Humans; Kinesins; Microtubules; Mitosis; Mitosis Modulators; Nuclear Matrix-Associated Proteins; Octamer Transcription Factors; Paclitaxel; Phosphorylation; RNA-Binding Proteins; Tandem Mass Spectrometry; Tubulin Modulators; Vincristine

2009
Effects of chemical manipulation of mitotic arrest and slippage on cancer cell survival and proliferation.
    Cell cycle (Georgetown, Tex.), 2009, Sep-15, Volume: 8, Issue:18

    Topics: Cell Line, Tumor; Cell Proliferation; Cell Survival; Chlorpromazine; Cysteine; Flavones; Humans; Indoles; Microtubules; Mitosis; Paclitaxel; Sulfonamides; Triflupromazine; Vinblastine

2009
Genome-free viral capsids as multivalent carriers for taxol delivery.
    Angewandte Chemie (International ed. in English), 2009, Volume: 48, Issue:50

    Topics: Antineoplastic Agents; Breast Neoplasms; Capsid; Capsid Proteins; Cell Line, Tumor; Cell Survival; Cross-Linking Reagents; Cysteine; Drug Carriers; Female; Genome, Viral; Humans; Paclitaxel

2009
Proteomic analysis of annexin A2 phosphorylation induced by microtubule interfering agents and kinesin spindle protein inhibitors.
    Journal of proteome research, 2010, Sep-03, Volume: 9, Issue:9

    Topics: Amino Acid Sequence; Annexin A2; Apoptosis; Blotting, Western; Cell Line, Tumor; Cyclin-Dependent Kinases; Cysteine; Electrophoresis, Gel, Two-Dimensional; Humans; Kinesins; Mitosis; Molecular Sequence Data; Paclitaxel; Peptide Mapping; Phosphorylation; Phosphothreonine; Proteomics; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Tubulin Modulators; Vinblastine

2010
Reduction-responsive polymeric micelles for anticancer drug delivery.
    Journal of controlled release : official journal of the Controlled Release Society, 2011, Nov-30, Volume: 152 Suppl 1

    Topics: Antineoplastic Agents, Phytogenic; Cell Survival; Chemistry, Pharmaceutical; Cysteine; Disulfides; Dose-Response Relationship, Drug; Drug Carriers; Drug Compounding; Hep G2 Cells; Humans; Hydrophobic and Hydrophilic Interactions; Magnetic Resonance Spectroscopy; Methylmethacrylate; Micelles; Paclitaxel; Polyethylene Glycols; Polymers; Solubility; Technology, Pharmaceutical

2011
Effects of cysteine on the pharmacokinetics of paclitaxel in rats.
    Archives of pharmacal research, 2012, Volume: 35, Issue:3

    Topics: Administration, Oral; Animals; Antineoplastic Agents, Phytogenic; Area Under Curve; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biotransformation; Cysteine; Cytochrome P-450 CYP3A; Drug Interactions; Injections, Intravenous; Intestinal Mucosa; Intestines; Male; Metabolic Clearance Rate; Microsomes, Liver; Paclitaxel; Protein Binding; Rats; Rats, Sprague-Dawley

2012
A nontoxic disulfide bond reducing method for lipophilic drug-loaded albumin nanoparticle preparation: formation dynamics, influencing factors and formation mechanisms investigation.
    International journal of pharmaceutics, 2013, Feb-25, Volume: 443, Issue:1-2

    Topics: Chemistry, Pharmaceutical; Cysteine; Disulfides; Drug Carriers; Drug Compounding; Nanoparticles; Oxidation-Reduction; Paclitaxel; Particle Size; Serum Albumin, Bovine; Solubility; Surface Properties

2013
Antibody conjugated PLGA nanoparticles for targeted delivery of paclitaxel palmitate: efficacy and biofate in a lung cancer mouse model.
    Small (Weinheim an der Bergstrasse, Germany), 2013, Dec-20, Volume: 9, Issue:24

    Topics: Amides; Animals; Antibodies; Antibodies, Monoclonal, Humanized; Area Under Curve; Cell Line, Tumor; Cetuximab; Cysteine; Drug Delivery Systems; ErbB Receptors; Humans; Immunotherapy; Lactic Acid; Lung Neoplasms; Mice; Mice, SCID; Nanoparticles; Nanotechnology; Neoplasm Transplantation; Paclitaxel; Palmitates; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Sulfhydryl Compounds; Surface Plasmon Resonance; Surface Properties

2013
Pluronic-poly (acrylic acid)-cysteine/Pluronic L121 mixed micelles improve the oral bioavailability of paclitaxel.
    Drug development and industrial pharmacy, 2014, Volume: 40, Issue:11

    Topics: Acrylic Resins; Administration, Oral; Animals; Area Under Curve; Biological Availability; Cysteine; Drug Carriers; Intestinal Absorption; Male; Micelles; Paclitaxel; Particle Size; Poloxamer; Rats; Rats, Wistar; Verapamil

2014
Investigation of Paclitaxel Resistant R306C Mutation in β-Tubulin—A Computational Approach.
    Journal of cellular biochemistry, 2015, Volume: 116, Issue:7

    Topics: Antineoplastic Agents, Phytogenic; Arginine; Binding Sites; Computational Biology; Cysteine; Drug Resistance, Neoplasm; Humans; Hydrogen Bonding; Molecular Docking Simulation; Molecular Dynamics Simulation; Mutation; Paclitaxel; Protein Binding; Protein Stability; Tubulin

2015
Cysteine modified and bile salt based micelles: preparation and application as an oral delivery system for paclitaxel.
    Colloids and surfaces. B, Biointerfaces, 2015, Apr-01, Volume: 128

    Topics: Administration, Oral; Animals; Antineoplastic Agents, Phytogenic; Area Under Curve; Biological Availability; Cell Survival; Chitosan; Cysteine; Drug Carriers; Drug Stability; Humans; Male; MCF-7 Cells; Micelles; Paclitaxel; Poloxamer; Rats; Rats, Wistar; Sodium Cholate; Surface-Active Agents

2015
Cys34-PEGylated Human Serum Albumin for Drug Binding and Delivery.
    Bioconjugate chemistry, 2015, May-20, Volume: 26, Issue:5

    Topics: Cell Survival; Chemistry, Pharmaceutical; Cysteine; Drug Carriers; Humans; Maleimides; MCF-7 Cells; Models, Molecular; Nanoparticles; Paclitaxel; Permeability; Polyethylene Glycols; Protein Conformation; Serum Albumin

2015
Downregulation of importin-9 protects MCF-7 cells against apoptosis induced by the combination of garlic-derived alliin and paclitaxel.
    Oncology reports, 2016, Volume: 35, Issue:5

    Topics: Actins; Active Transport, Cell Nucleus; Antineoplastic Agents, Phytogenic; Apoptosis; Breast Neoplasms; Cofilin 1; Cysteine; Down-Regulation; Drug Screening Assays, Antitumor; Drug Synergism; Female; Garlic; Humans; Karyopherins; MCF-7 Cells; Paclitaxel

2016
Anticancer activity of drug conjugates in head and neck cancer cells.
    Frontiers in bioscience (Elite edition), 2016, 06-01, Volume: 8, Issue:3

    Topics: Antineoplastic Agents; Carcinoma, Squamous Cell; Cell Line, Tumor; Cysteine; Esters; Head and Neck Neoplasms; Humans; Hydrogen-Ion Concentration; Nuclear Magnetic Resonance, Biomolecular; Paclitaxel; Papillomavirus Infections; Sexually Transmitted Diseases

2016
Sulfo-SMCC Prevents Annealing of Taxol-Stabilized Microtubules In Vitro.
    PloS one, 2016, Volume: 11, Issue:8

    Topics: Animals; Antineoplastic Agents, Phytogenic; Cysteine; Esters; Maleimides; Microtubules; Paclitaxel; Polymers; Succinimides; Swine; Tubulin

2016
Paclitaxel-induced aberrant mitosis and mitotic slippage efficiently lead to proliferative death irrespective of canonical apoptosis and p53.
    Cell cycle (Georgetown, Tex.), 2016, Volume: 15, Issue:23

    Topics: Apoptosis; Cell Cycle Checkpoints; Cell Proliferation; Cell Survival; Clone Cells; Cysteine; DNA; Genes, Reporter; HeLa Cells; Humans; Kinesins; Melanoma; Mitochondrial Membranes; Mitosis; Paclitaxel; Permeability; Phenotype; Reproducibility of Results; Time-Lapse Imaging; Tumor Suppressor Protein p53

2016
Tension-Induced Error Correction and Not Kinetochore Attachment Status Activates the SAC in an Aurora-B/C-Dependent Manner in Oocytes.
    Current biology : CB, 2018, 01-08, Volume: 28, Issue:1

    Topics: Animals; Cell Division; Cysteine; Female; Kinesins; Kinetochores; M Phase Cell Cycle Checkpoints; Meiosis; Mice; Oocytes; Paclitaxel; Pyrimidines; Thiones; Tubulin Modulators

2018
Optimised approach to albumin-drug conjugates using monobromomaleimide-C-2 linkers.
    Organic & biomolecular chemistry, 2019, 08-28, Volume: 17, Issue:34

    Topics: Antineoplastic Agents; Cell Line, Tumor; Cysteine; Drug Stability; Humans; Hydrolysis; Maleimides; Paclitaxel; Serum Albumin, Human

2019
Polylysine and cysteine functionalized chitosan nanoparticle as an efficient platform for oral delivery of paclitaxel.
    Carbohydrate polymers, 2020, Feb-01, Volume: 229

    Topics: Administration, Oral; Animals; Caco-2 Cells; Chitosan; Cysteine; Drug Carriers; Humans; Mice; Nanoparticles; Paclitaxel; Polylysine; Rats; Rats, Sprague-Dawley; Tissue Distribution; Xenograft Model Antitumor Assays

2020
Biodegradable gellan gum hydrogels loaded with paclitaxel for HER2+ breast cancer local therapy.
    Carbohydrate polymers, 2022, Oct-15, Volume: 294

    Topics: Breast Neoplasms; Cysteine; Female; Humans; Hydrogels; Paclitaxel; Polysaccharides, Bacterial

2022
Gomisin A enhances the antitumor effect of paclitaxel by suppressing oxidative stress in ovarian cancer.
    Oncology reports, 2022, Volume: 48, Issue:5

    Topics: Animals; Carcinoma, Ovarian Epithelial; Cell Line, Tumor; Cell Proliferation; Complex Mixtures; Cyclin B1; Cyclin-Dependent Kinase 4; Cyclooctanes; Cysteine; Dioxoles; Eosine Yellowish-(YS); Female; Humans; Lignans; Mice; Ovarian Neoplasms; Oxidative Stress; Paclitaxel; Reactive Oxygen Species

2022
A Ferroptosis-Inducing and Leukemic Cell-Targeting Drug Nanocarrier Formed by Redox-Responsive Cysteine Polymer for Acute Myeloid Leukemia Therapy.
    ACS nano, 2023, 02-28, Volume: 17, Issue:4

    Topics: Animals; Cysteine; Ferroptosis; Leukemia, Myeloid, Acute; Mice; Oxidation-Reduction; Paclitaxel; Polymers

2023