cysteine and nsc 83265

cysteine has been researched along with nsc 83265 in 46 studies

Research

Studies (46)

TimeframeStudies, this research(%)All Research%
pre-19901 (2.17)18.7374
1990's0 (0.00)18.2507
2000's14 (30.43)29.6817
2010's31 (67.39)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Baronowsky, PE; Coffey, JJ; Denine, EP; Kensler, CJ; Palm, PE1
Estes, LA; Kelner, MJ; McMorris, TC; Rojas, RJ; Suthipinijtham, P; Trani, NA; Velasco, TR1
DeBonis, S; Kozielski, F; Lebeau, L; Lopez, R; Margolis, RL; Robin, G; Skoufias, DA; Wade, RH1
Brier, S; Debonis, S; Forest, E; Kozielski, F; Lemaire, D2
Crevel, I; Cross, R; DeBonis, S; Hackney, D; Kozielski, F; Lebeau, L; Saoudi, Y; Skoufias, DA; Wade, RH1
Bernhardt, G; Buschauer, A; Gartner, M; Giannis, A; Gross, D; Müller, C; Sarli, V1
Kropf, DL; Peters, NT1
Filatova, IS; Planas-Silva, MD1
Chen, Y; Jiang, C; Wang, X; You, Q1
Hustoft, HK; Indorato, RL; Jungblut, PR; Kozielski, F; Saoudi, Y; Skoufias, DA; Strozynski, M; Thiede, B1
Debonis, S; Indorato, RL; Joseph, B; Kozielski, F; Laggner, C; Liger, F; Marquet, B; Skoufias, DA1
Artime, N; Burlingame, AL; Cabal-Hierro, L; Casado, P; Del Valle, E; Lazo, PS; Prado, MA; Ramos, S; Rupérez, P; Zuazua-Villar, P1
Khong, A; McHardy, LM; Riffell, JL; Roberge, M; Zimmerman, C1
Field, CM; Mitchison, TJ; Monigatti, F; Ozlü, N; Renard, BY; Steen, H; Steen, JJ1
Hackney, DD; Kaan, HY; Kozielski, F; Ulaganathan, V1
Kozielski, F; Skoufias, DA; Tcherniuk, S; van Lis, R1
Asai, A; Ishii, H; Matsuno, K; Ogo, N; Shimizu, M1
Cooke, R; Larson, AG; Naber, N; Pate, E; Rice, SE1
Barnetson, R; Doyle, B; Fleming, J; Kozielski, F; Leung, HY; Robson, CN; Singh, BL; Stockley, J; Wiltshire, C1
Artime, N; Cabal-Hierro, L; Calvo, E; Casado, P; Fernandez-Garcia, B; Lazo, PS; López, JA; Prado, MA; Ramos, S; Ugarte-Gil, LJ1
Akiyama, Y; Asai, A; Ishii, H; Matsuno, K; Ogo, N; Sawada, J; Shimizu, M; Unno, Y1
Kim, S; Liu, J; Liu, L; Parameswaran, S; Wojcik, EJ1
Arntzen, MØ; Koehler, CJ; Strozynski, M; Thiede, B; Treumann, A1
Basu, A; Fournet, G; Gurukumar, KR; Joseph, B; Kaushik-Basu, N; Kozielski, F; Lee, JC; Musmuca, I; Nichols, DB; Ragno, R; Sakamoto, N1
Abualhasan, MN; Anthony, NG; Berretta, G; Good, JA; Kozielski, F; Mackay, SP; Rath, O; Sutcliffe, OB; Wittayanarakul, K1
Jungblut, PR; Koehler, CJ; Schmid, M; Stein, R; Strozynski, M; Thiede, B; Treumann, A; Zimny-Arndt, U1
Arntzen, MØ; de Souza, GA; Koehler, CJ; Thiede, B1
Good, JA; Kaan, HY; Kozielski, F; MacKay, SP; Podgórski, D; Rath, O; Talapatra, SK; Wang, F1
Chen, E; Li, R; Liu, XJ; Ma, C; Shao, H1
Cosenza, MR; Ellenberg, J; Fry, AM; Isokane, M; Krämer, A; Mardin, BR; Schiebel, E1
Boucrot, E; Kirchhausen, T; Santos, AJ; Tacheva-Grigorova, SK1
DeBonis, S; Garcia-Saez, I; Indorato, RL; Kozielski, F; Skoufias, DA1
Ishikawa, K; Maruta, S; Tamura, Y1
Barragan, J; Barresi, MJ; DiPietrantonio, K; Edens, B; Eisenman, J; Golé, C; Johnson, K; Krikorian, S; Moriarty, C; Ok, D; Ortman, A; Tania, N1
Ishikawa, K; Maruta, S; Mitsuhashi, S; Tohyama, K1
Chinen, T; Hayashi, T; Hirota, H; Ishii, Y; Kondo, H; Motoyama, T; Muroi, M; Nagumo, Y; Osada, H; Tarui, Y; Usui, T1
Bi, D; Ding, K; Ding, S; Lu, J; Sun, D; Sun, L; Wu, F; Wu, H; Xing, N; Zhao, Z1
Cattin, CJ; Helenius, J; Hyman, AA; Muller, DJ; Ramanathan, SP; Stewart, MP1
Ianni, F; Lisanti, A; Marinozzi, M; Natalini, B; Sardella, R; Scorzoni, S1
Guo, Y; Norris, SR; Ohi, R; Sturgill, EG1
Maesawa, C; Nishiya, M; Shibazaki, M; Yasuhira, S1
Bolte, S; Buffin, E; Cladière, D; El Yakoubi, W; Leontiou, I; Vallot, A; Wassmann, K1
Doita, M; Maesawa, C; Masuda, T; Saeki, E; Shibazaki, M; Tada, H; Yasuhira, S1
Božič, M; Bratuša, A; Elschner, T; Fröhlich, E; Heinze, T; Hribernik, S; Kargl, R; Kleinschek, KS; Thonhofer, M; Žagar, E1
Chang, Y; Cheng, E; Moore, PS; Sun, R; Velásquez, C1

Reviews

1 review(s) available for cysteine and nsc 83265

ArticleYear
S-trityl-(R)-cysteine, a multipurpose chiral selector for ligand-exchange liquid chromatography applications.
    Critical reviews in analytical chemistry, 2015, Volume: 45, Issue:4

    Topics: Animals; Chromatography, High Pressure Liquid; Chromatography, Ion Exchange; Cysteine; Humans; Ligands; Models, Molecular; Stereoisomerism

2015

Other Studies

45 other study(ies) available for cysteine and nsc 83265

ArticleYear
Species differences in the physiological disposition of 3-tritylthio-L-alanine (NSC83265).
    Cancer research, 1971, Volume: 31, Issue:12

    Topics: Animals; Antineoplastic Agents; Benzene Derivatives; Bile; Carbon Isotopes; Chromatography, Thin Layer; Colorimetry; Cysteine; Dogs; Half-Life; Haplorhini; Intestinal Absorption; Kinetics; Male; Physiology, Comparative; Rats; Species Specificity

1971
Enhanced antitumor activity of irofulven in combination with antimitotic agents.
    Investigational new drugs, 2002, Volume: 20, Issue:3

    Topics: Animals; Antibiotics, Antineoplastic; Antineoplastic Agents; Bridged-Ring Compounds; Cell Survival; Colchicine; Cysteine; Drug Synergism; Female; Lactones; Macrolides; Mice; Mice, Inbred BALB C; Neoplasm Transplantation; Sesquiterpenes; Taxoids; Tubulin; Tumor Cells, Cultured; Vinca Alkaloids

2002
In vitro screening for inhibitors of the human mitotic kinesin Eg5 with antimitotic and antitumor activities.
    Molecular cancer therapeutics, 2004, Volume: 3, Issue:9

    Topics: Adenosine Triphosphatases; Antineoplastic Agents; Biological Assay; Cysteine; HeLa Cells; Humans; Inhibitory Concentration 50; Kinesins; Mitosis; Spindle Apparatus

2004
Identification of the protein binding region of S-trityl-L-cysteine, a new potent inhibitor of the mitotic kinesin Eg5.
    Biochemistry, 2004, Oct-19, Volume: 43, Issue:41

    Topics: Adenosine Triphosphatases; Amino Acid Sequence; Antineoplastic Agents; Cysteine; Deuterium Exchange Measurement; Genetic Vectors; Growth Inhibitors; Humans; Kinesins; Mitosis; Molecular Motor Proteins; Molecular Sequence Data; Neurospora crassa; Peptide Fragments; Protein Binding; Protein Structure, Tertiary; Pyrimidines; Spectrometry, Mass, Electrospray Ionization; Thiones

2004
S-trityl-L-cysteine is a reversible, tight binding inhibitor of the human kinesin Eg5 that specifically blocks mitotic progression.
    The Journal of biological chemistry, 2006, Jun-30, Volume: 281, Issue:26

    Topics: Adenosine Diphosphate; Animals; Bone Neoplasms; Cattle; Cell Division; Cysteine; Drug Design; HeLa Cells; Humans; Kinesins; Mitosis; ortho-Aminobenzoates; Osteosarcoma; Protein Binding; Protein Structure, Tertiary; Recombinant Proteins; Spindle Apparatus; Stereoisomerism

2006
Inhibitors of kinesin Eg5: antiproliferative activity of monastrol analogues against human glioblastoma cells.
    Cancer chemotherapy and pharmacology, 2007, Volume: 59, Issue:2

    Topics: Acridines; Antineoplastic Agents, Phytogenic; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cell Line, Tumor; Cell Proliferation; Cell Survival; Cysteine; Dose-Response Relationship, Drug; Flow Cytometry; Fluoresceins; Glioblastoma; Humans; Insecticides; Kinesins; Molecular Structure; Paclitaxel; Pyrimidines; Quinazolines; Rotenone; Spindle Apparatus; Tetrahydroisoquinolines; Thiones; Time Factors; Tubulin; Tubulin Modulators; Vinblastine

2007
Molecular dissection of the inhibitor binding pocket of mitotic kinesin Eg5 reveals mutants that confer resistance to antimitotic agents.
    Journal of molecular biology, 2006, Jul-07, Volume: 360, Issue:2

    Topics: Amino Acid Sequence; Antimitotic Agents; Binding Sites; Cysteine; Drug Resistance; Kinesins; Kinetics; Mass Spectrometry; Mitosis; Models, Molecular; Molecular Sequence Data; Mutagenesis; Point Mutation; Protein Binding; Pyrimidines; Thiones

2006
Kinesin-5 motors are required for organization of spindle microtubules in Silvetia compressa zygotes.
    BMC plant biology, 2006, Aug-31, Volume: 6

    Topics: Cell Polarity; Cysteine; Cytokinesis; Dinitrobenzenes; Kinesins; Microtubules; Mitosis; Molecular Motor Proteins; Paclitaxel; Phaeophyceae; Pyrimidines; Spindle Apparatus; Sulfanilamides; Thiones; Zygote

2006
Estrogen-dependent regulation of Eg5 in breast cancer cells.
    Anti-cancer drugs, 2007, Volume: 18, Issue:7

    Topics: Blotting, Western; Breast Neoplasms; Cell Cycle; Cell Line, Tumor; Cysteine; Dose-Response Relationship, Drug; Down-Regulation; Estradiol; Estrogen Antagonists; Estrogens; Female; Flow Cytometry; Fulvestrant; Humans; Inhibitory Concentration 50; Kinesins; Mitosis; Pyrimidines; Receptors, Estrogen; Signal Transduction; Thiones; Up-Regulation

2007
Docking studies on kinesin spindle protein inhibitors: an important cooperative 'minor binding pocket' which increases the binding affinity significantly.
    Journal of molecular modeling, 2007, Volume: 13, Issue:9

    Topics: Amino Acid Sequence; Amino Acids; Cysteine; Diterpenes; Hydrogen Bonding; Indoles; Kinesins; Models, Molecular; Phenols; Protein Binding; Pyrimidines; Spindle Apparatus; Thiones

2007
Proteome analysis of apoptosis signaling by S-trityl-L-cysteine, a potent reversible inhibitor of human mitotic kinesin Eg5.
    Proteomics, 2008, Volume: 8, Issue:2

    Topics: Apoptosis; Cysteine; HeLa Cells; Humans; Kinesins; Mitosis; Paclitaxel; Proteome; Signal Transduction

2008
Structure-activity relationship of S-trityl-L-cysteine analogues as inhibitors of the human mitotic kinesin Eg5.
    Journal of medicinal chemistry, 2008, Mar-13, Volume: 51, Issue:5

    Topics: Antineoplastic Agents; Binding Sites; Cell Line, Tumor; Crystallography, X-Ray; Cysteine; Drug Screening Assays, Antitumor; Humans; Kinesins; Mitosis; Models, Molecular; Protein Binding

2008
Microtubule interfering agents and KSP inhibitors induce the phosphorylation of the nuclear protein p54(nrb), an event linked to G2/M arrest.
    Journal of proteomics, 2009, Jan-30, Volume: 71, Issue:6

    Topics: Antineoplastic Agents, Phytogenic; Cell Line; Cisplatin; Cysteine; DNA-Binding Proteins; Electrophoresis, Gel, Two-Dimensional; G2 Phase; Humans; Kinesins; Microtubules; Mitosis; Mitosis Modulators; Nuclear Matrix-Associated Proteins; Octamer Transcription Factors; Paclitaxel; Phosphorylation; RNA-Binding Proteins; Tandem Mass Spectrometry; Tubulin Modulators; Vincristine

2009
Effects of chemical manipulation of mitotic arrest and slippage on cancer cell survival and proliferation.
    Cell cycle (Georgetown, Tex.), 2009, Sep-15, Volume: 8, Issue:18

    Topics: Cell Line, Tumor; Cell Proliferation; Cell Survival; Chlorpromazine; Cysteine; Flavones; Humans; Indoles; Microtubules; Mitosis; Paclitaxel; Sulfonamides; Triflupromazine; Vinblastine

2009
Binding partner switching on microtubules and aurora-B in the mitosis to cytokinesis transition.
    Molecular & cellular proteomics : MCP, 2010, Volume: 9, Issue:2

    Topics: Aurora Kinase B; Aurora Kinases; Cell Cycle Proteins; Cysteine; Cytokinesis; HeLa Cells; Humans; Interphase; Isotope Labeling; Microtubules; Mitosis; Models, Biological; Phosphorylation; Protein Binding; Protein Serine-Threonine Kinases

2010
An allosteric transition trapped in an intermediate state of a new kinesin-inhibitor complex.
    The Biochemical journal, 2009, Dec-14, Volume: 425, Issue:1

    Topics: Allosteric Regulation; Allosteric Site; Binding Sites; Crystallography, X-Ray; Cysteine; Humans; Kinesins; Kinetics; Models, Molecular; Protein Binding; Protein Conformation; Protein Structure, Tertiary; Structure-Activity Relationship

2009
Mutations in the human kinesin Eg5 that confer resistance to monastrol and S-trityl-L-cysteine in tumor derived cell lines.
    Biochemical pharmacology, 2010, Mar-15, Volume: 79, Issue:6

    Topics: Antineoplastic Agents; Binding Sites; Cysteine; Drug Resistance; Humans; Inhibitory Concentration 50; Kinesins; Models, Molecular; Mutation; Protein Binding; Pyrimidines; Thiones

2010
Biochemical analysis of cellular target of S-trityl-L-cysteine derivatives using affinity matrix.
    Bioorganic & medicinal chemistry letters, 2010, Mar-01, Volume: 20, Issue:5

    Topics: Antineoplastic Agents; Cell Line, Tumor; Cysteine; Enzyme Inhibitors; Humans; Immobilized Proteins; Kinesins; Protein Binding

2010
The conserved L5 loop establishes the pre-powerstroke conformation of the Kinesin-5 motor, eg5.
    Biophysical journal, 2010, Jun-02, Volume: 98, Issue:11

    Topics: Allosteric Regulation; Cysteine; Electron Spin Resonance Spectroscopy; Escherichia coli; Kinesins; Microtubules; Models, Molecular; Motion; Protein Conformation

2010
Docetaxel-resistant prostate cancer cells remain sensitive to S-trityl-L-cysteine-mediated Eg5 inhibition.
    Molecular cancer therapeutics, 2010, Volume: 9, Issue:6

    Topics: Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cell Line, Tumor; Cysteine; Docetaxel; Drug Screening Assays, Antitumor; Humans; Kinesins; Male; Propidium; Prostatic Neoplasms; Taxoids; Up-Regulation

2010
Proteomic analysis of annexin A2 phosphorylation induced by microtubule interfering agents and kinesin spindle protein inhibitors.
    Journal of proteome research, 2010, Sep-03, Volume: 9, Issue:9

    Topics: Amino Acid Sequence; Annexin A2; Apoptosis; Blotting, Western; Cell Line, Tumor; Cyclin-Dependent Kinases; Cysteine; Electrophoresis, Gel, Two-Dimensional; Humans; Kinesins; Mitosis; Molecular Sequence Data; Paclitaxel; Peptide Mapping; Phosphorylation; Phosphothreonine; Proteomics; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Tubulin Modulators; Vinblastine

2010
S-trityl-L-cysteine derivative induces caspase-independent cell death in K562 human chronic myeloid leukemia cell line.
    Cancer letters, 2010, Dec-01, Volume: 298, Issue:1

    Topics: Apoptosis; Caspases; Cell Cycle; Cell Growth Processes; Cell Line, Tumor; Cysteine; Humans; K562 Cells; Leukemia, Myelogenous, Chronic, BCR-ABL Positive

2010
Loop 5-directed compounds inhibit chimeric kinesin-5 motors: implications for conserved allosteric mechanisms.
    The Journal of biological chemistry, 2011, Feb-25, Volume: 286, Issue:8

    Topics: Allosteric Regulation; Animals; Cysteine; Drosophila melanogaster; Drosophila Proteins; Humans; Kinesins; Microtubule-Associated Proteins; Protein Binding; Protein Structure, Secondary; Protein Structure, Tertiary; Pyrimidines; Recombinant Fusion Proteins; Thiones

2011
Isobaric peptide termini labeling utilizing site-specific N-terminal succinylation.
    Analytical chemistry, 2011, Jun-15, Volume: 83, Issue:12

    Topics: Algorithms; Apoptosis; Chromatography, High Pressure Liquid; Cysteine; HeLa Cells; Humans; Lysine; Peptides; Proteome; Succinic Anhydrides; Tandem Mass Spectrometry

2011
Inhibition of hepatitis C virus NS5B polymerase by S-trityl-L-cysteine derivatives.
    European journal of medicinal chemistry, 2012, Volume: 49

    Topics: Antiviral Agents; Cell Line; Cysteine; Enzyme Inhibitors; Hepacivirus; Hepatitis C; Humans; Models, Molecular; RNA-Dependent RNA Polymerase; RNA, Viral

2012
Doing the methylene shuffle--further insights into the inhibition of mitotic kinesin Eg5 with S-trityl L-cysteine.
    European journal of medicinal chemistry, 2012, Volume: 54

    Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Cysteine; Drug Resistance, Multiple; Enzyme Inhibitors; Humans; Hydrophobic and Hydrophilic Interactions; Kinesins; Molecular Dynamics Simulation; Protein Conformation; Structure-Activity Relationship; Thermodynamics

2012
High resolution quantitative proteomics of HeLa cells protein species using stable isotope labeling with amino acids in cell culture(SILAC), two-dimensional gel electrophoresis(2DE) and nano-liquid chromatograpohy coupled to an LTQ-OrbitrapMass spectromet
    Molecular & cellular proteomics : MCP, 2013, Volume: 12, Issue:2

    Topics: Apoptosis; Artifacts; Chromatography, Liquid; Cysteine; Electrophoresis, Gel, Two-Dimensional; HeLa Cells; Humans; Isotope Labeling; Mass Spectrometry; Peptides; Proteome; Proteomics; Rosaniline Dyes

2013
An approach for triplex-isobaric peptide termini labeling (triplex-IPTL).
    Analytical chemistry, 2013, Feb-19, Volume: 85, Issue:4

    Topics: Apoptosis; Carbon Isotopes; Cell Cycle Checkpoints; Cysteine; Deuterium; HeLa Cells; Humans; Isotope Labeling; Peptides; Tandem Mass Spectrometry

2013
Optimized S-trityl-L-cysteine-based inhibitors of kinesin spindle protein with potent in vivo antitumor activity in lung cancer xenograft models.
    Journal of medicinal chemistry, 2013, Mar-14, Volume: 56, Issue:5

    Topics: Animals; Antineoplastic Agents; Benzamides; Butylamines; Cell Line, Tumor; Chromones; Cysteine; Kinesins; Lung Neoplasms; Mice; Mice, Nude; Neoplasm Transplantation; Quinazolines; Structure-Activity Relationship; Transplantation, Heterologous

2013
Xenopus oocyte meiosis lacks spindle assembly checkpoint control.
    The Journal of cell biology, 2013, Apr-15, Volume: 201, Issue:2

    Topics: Anaphase; Animals; Aurora Kinases; cdc42 GTP-Binding Protein; Cell Polarity; Chromosomes; Cyclin B; Cysteine; Demecolcine; Enzyme Activation; Female; Karyotyping; M Phase Cell Cycle Checkpoints; Meiosis; Metaphase; Microtubules; Nocodazole; Oocytes; Protein Serine-Threonine Kinases; Proteolysis; Spindle Apparatus; Time Factors; Xenopus

2013
EGF-induced centrosome separation promotes mitotic progression and cell survival.
    Developmental cell, 2013, May-13, Volume: 25, Issue:3

    Topics: Cell Proliferation; Cell Survival; Centrosome; Cysteine; DNA Replication; Enzyme Activation; Epidermal Growth Factor; ErbB Receptors; HeLa Cells; Humans; Kinesins; Mitosis; NIMA-Related Kinases; Protein Serine-Threonine Kinases; S Phase Cell Cycle Checkpoints; Serine-Threonine Kinase 3; Signal Transduction; Spindle Apparatus; Time Factors; Transfection

2013
Clathrin-mediated endocytosis persists during unperturbed mitosis.
    Cell reports, 2013, Aug-29, Volume: 4, Issue:4

    Topics: Animals; Chlorocebus aethiops; Clathrin; Clathrin-Coated Vesicles; Cysteine; Endocytosis; HEK293 Cells; HeLa Cells; Hot Temperature; Humans; Mitosis; Nocodazole; Quinolines; Thiazoles; Transferrin

2013
STLC-resistant cell lines as tools to classify chemically divergent Eg5 targeting agents according to their mode of action and target specificity.
    Biochemical pharmacology, 2013, Nov-15, Volume: 86, Issue:10

    Topics: Adenosine Triphosphatases; Adenosine Triphosphate; Allosteric Site; Antineoplastic Agents; Binding Sites; Cell Line, Tumor; Cell Proliferation; Cysteine; Drug Resistance, Neoplasm; Humans; Kinesins; M Phase Cell Cycle Checkpoints; Point Mutation; Quinazolines; Thiadiazoles; Thiones

2013
Photocontrol of mitotic kinesin Eg5 facilitated by thiol-reactive photochromic molecules incorporated into the loop L5 functional loop.
    Journal of biochemistry, 2014, Volume: 155, Issue:3

    Topics: Absorption; Animals; Azo Compounds; Cysteine; Kinesins; Kinetics; Mice; Microtubules; Mitosis; Molecular Probes; Mutant Proteins; Photochemical Processes; Protein Structure, Secondary; Spectrum Analysis; Sulfhydryl Compounds; Sus scrofa

2014
Kif11 dependent cell cycle progression in radial glial cells is required for proper neurogenesis in the zebrafish neural tube.
    Developmental biology, 2014, Mar-01, Volume: 387, Issue:1

    Topics: Animals; Apoptosis; Caspase 3; Cell Count; Cell Proliferation; Cysteine; Ependymoglial Cells; Kinesins; M Phase Cell Cycle Checkpoints; Mitosis; Motor Neurons; Neural Stem Cells; Neural Tube; Neurogenesis; Oligodendroglia; Zebrafish; Zebrafish Proteins

2014
Photocontrol of the mitotic kinesin Eg5 using a novel S-trityl-L-cysteine analogue as a photochromic inhibitor.
    Journal of biochemistry, 2014, Volume: 155, Issue:4

    Topics: Absorption; Animals; Azo Compounds; Cysteine; Isomerism; Kinesins; Kinetics; Light; Mice; Microtubules; Mitosis; Photochemical Processes; Spectrum Analysis; Sus scrofa

2014
Terpendole E and its derivative inhibit STLC- and GSK-1-resistant Eg5.
    Chembiochem : a European journal of chemical biology, 2014, May-05, Volume: 15, Issue:7

    Topics: Cell Survival; Cysteine; Diterpenes; Electrophoresis, Gel, Two-Dimensional; HeLa Cells; Humans; Indoles; Kinesins; Kinetics; Magnetic Resonance Spectroscopy; Microtubules; Mutagenesis; Oligopeptides; Proteome

2014
Eg5 inhibitor, a novel potent targeted therapy, induces cell apoptosis in renal cell carcinoma.
    Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine, 2014, Volume: 35, Issue:8

    Topics: Animals; Antineoplastic Agents; Apoptosis; Carcinoma, Renal Cell; Cell Cycle Checkpoints; Cell Line, Tumor; Cysteine; Female; Humans; Kidney Neoplasms; Kinesins; Mice; Mice, Inbred BALB C; Molecular Targeted Therapy; Trityl Compounds; Xenograft Model Antitumor Assays

2014
Cdk1-dependent mitotic enrichment of cortical myosin II promotes cell rounding against confinement.
    Nature cell biology, 2015, Volume: 17, Issue:2

    Topics: Actins; Actomyosin; CDC2 Protein Kinase; Cysteine; Fetal Proteins; Formins; Green Fluorescent Proteins; HeLa Cells; Humans; Intracellular Space; Microfilament Proteins; Microscopy, Atomic Force; Mitosis; Models, Biological; Myosin Type II; Nuclear Proteins; Pressure; rho GTP-Binding Proteins; rho-Associated Kinases; Time Factors

2015
Kinesin-5 inhibitor resistance is driven by kinesin-12.
    The Journal of cell biology, 2016, 04-25, Volume: 213, Issue:2

    Topics: Cysteine; HeLa Cells; Humans; Kinesins; Spindle Apparatus

2016
Paclitaxel-induced aberrant mitosis and mitotic slippage efficiently lead to proliferative death irrespective of canonical apoptosis and p53.
    Cell cycle (Georgetown, Tex.), 2016, Volume: 15, Issue:23

    Topics: Apoptosis; Cell Cycle Checkpoints; Cell Proliferation; Cell Survival; Clone Cells; Cysteine; DNA; Genes, Reporter; HeLa Cells; Humans; Kinesins; Melanoma; Mitochondrial Membranes; Mitosis; Paclitaxel; Permeability; Phenotype; Reproducibility of Results; Time-Lapse Imaging; Tumor Suppressor Protein p53

2016
Tension-Induced Error Correction and Not Kinetochore Attachment Status Activates the SAC in an Aurora-B/C-Dependent Manner in Oocytes.
    Current biology : CB, 2018, 01-08, Volume: 28, Issue:1

    Topics: Animals; Cell Division; Cysteine; Female; Kinesins; Kinetochores; M Phase Cell Cycle Checkpoints; Meiosis; Mice; Oocytes; Paclitaxel; Pyrimidines; Thiones; Tubulin Modulators

2018
Involvement of C-terminal truncation mutation of kinesin-5 in resistance to kinesin-5 inhibitor.
    PloS one, 2018, Volume: 13, Issue:12

    Topics: Antimitotic Agents; Cell Line, Tumor; Cell Survival; Cysteine; Drug Resistance; Dyneins; Gene Expression; Gene Knockdown Techniques; HeLa Cells; Humans; Kinesins; Mutation; Nuclear Envelope; Spindle Apparatus

2018
Functional dextran amino acid ester particles derived from N-protected S-trityl-L-cysteine.
    Colloids and surfaces. B, Biointerfaces, 2019, Sep-01, Volume: 181

    Topics: Amino Acids; Cysteine; Dextrans; Esters; Particle Size; Surface Properties

2019
Mitosis-related phosphorylation of the eukaryotic translation suppressor 4E-BP1 and its interaction with eukaryotic translation initiation factor 4E (eIF4E).
    The Journal of biological chemistry, 2019, 08-02, Volume: 294, Issue:31

    Topics: Adaptor Proteins, Signal Transducing; Cell Cycle Proteins; Cysteine; Eukaryotic Initiation Factor-4E; Eukaryotic Initiation Factor-4G; Gene Editing; HeLa Cells; Humans; Interphase; Mitosis; Phosphorylation; Protein Binding; Protein Isoforms

2019