cysteine and naphthoquinones

cysteine has been researched along with naphthoquinones in 48 studies

Research

Studies (48)

TimeframeStudies, this research(%)All Research%
pre-199011 (22.92)18.7374
1990's6 (12.50)18.2507
2000's13 (27.08)29.6817
2010's15 (31.25)24.3611
2020's3 (6.25)2.80

Authors

AuthorsStudies
Hara, M; Harigai, M; Hidaka, T; Ishizuka, T; Kawagoe, M; Kawaguchi, Y; Kawakami, M; Kitani, A; Nakamura, H; Suzuki, K1
Murty, VS; Penning, TM1
Driessen, AJ; Kaback, HR; Konings, WN; Menick, DR; van Iwaarden, PR1
Ishimaru, T; Kanamaru, T; Ohta, K; Okazaki, H1
Ishimaru, T; Kanamaru, T; Kasahara, F; Ohta, K; Okazaki, H; Wada, Y1
Ishimaru, T; Kanamaru, T; Okazaki, H; Takahashi, T1
Dendy, PP; Morley, TG1
Gause, EM; Montalvo, DA; Rowlands, JR1
Nakai, N; Nishibayashi, H; Sato, R1
Pirie, A1
Ambrogi, V; Artini, D; Castellino, S; De Carneri, I; Di Somma, M; Dradi, E; Logemann, W; Meinardi, G; Tosolini, G; Vecchi, E1
Ferkovich, SM; Norris, DM1
Ichikawa, H; Ozawa, H1
Ohnishi, Y; Okada, Y; Ooshima, A; Saika, S; Tanaka, S; Yamanaka, O1
Christner, C; Fischer, G; Grabley, S; Hennig, L; Kipping, M; Küllertz, G; Rücknagel, KP; Schelbert, B1
Allen, G; Cooper, D; Ertl, P; Slater, MJ1
Chen, AY; LaVoie, EJ; Liu, LF; Mao, Y; Wang, H; Zhou, N1
Bazzi, MD1
Abreu, FC; Goulart, MO; Oliveira-Brett, AM1
Kupper, LL; Lindstrom, AB; Rappaport, SM; Troester, MA; Waidyanatha, S1
TATSUNO, T; UENO, I; UENO, Y; URAGUCHI, K1
Briggs, MK; Desavis, E; Hadad, CM; Hatcher, PG; Hatcher, SA; Mazzer, PA; Sunoj, RB1
Austin, MB; Bowman, ME; Ferrer, JL; Izumikawa, M; Moore, BS; Noel, JP; Udwary, DW1
Av-Gay, Y; Fahey, RC; Newton, G; Rawat, M; Steffek, M; Uppal, M1
Douglas, KT; Guedes, RC; Iley, J; Jaffar, M; Moreira, R; Valente, C1
Abraham, RT; Barbieri, LR; Bernan, VS; Cai, P; Ding, WD; Gibbons, JJ; Hu, YB; Huang, X; Krishnamurthy, G; Levin, JI; Lucas, J; Mansour, TS; McDonald, LA; Salaski, EJ; Toral-Barza, L; Yu, K; Zhang, WG1
Fila, C; Metz, C; van der Sluijs, P1
Cho, S; Dreyfuss, G; Ottinger, E; Wan, L1
Hertweck, C; Metsä-Ketelä, M; Xu, Z1
Ding, WD; Eid, C; Hanna, C; Honores, E; Insaf, SS; Johnson, B; Krishnamurthy, G; Laakso, L; Levin, JI; Li, Z; Mansour, TS; McDonald, LA; Powell, D; Salaski, EJ; Shim, J; Tabei, K; Toral-Barza, L; Yamashita, A; Yu, K; Zhang, WG1
Gammon, DW; Hunter, R; Marakalala, MJ; Mavumengwana, V; Mudzunga, TT; Munyololo, M; Steenkamp, DJ1
Slomiany, A; Slomiany, BL1
Endo, A; Iwamoto, N; Kumagai, Y; Sumi, D1
Dicesare, JC; Kennedy, S; Sheaff, RJ1
Almo, SC; Bresnick, AR; Dulyaninova, NG; Hite, KM; Scudiero, DA; Shoemaker, RH; Zencheck, WD1
Cho, AK; Kumagai, Y; Miura, T; Shinkai, Y1
Cho, AK; Ishii, T; Iwamoto, N; Kumagai, Y; Miura, T; Shinkai, Y1
Hartmanová, T; Lenčo, J; Maser, E; Staab-Weijnitz, CA; Tambor, V; Wsól, V1
Gammon, DW; Naidoo, KJ; Rogers, IL1
Broniowska, KA; Diers, AR; Hogg, N1
Kaji, T; Kakehashi, H; Kumagai, Y; Shinkai, Y; Toyama, T; Yazawa, A1
Abiko, Y; Akaike, T; Ida, T; Ishii, I; Kakehashi, H; Kumagai, Y; Miura, T; Nishida, M; Sawa, T; Shinkai, Y1
Arnér, ES; Cheng, Q; Xu, J1
Abiko, Y; Akaike, T; Hirose, R; Kumagai, Y; Luong, NC; Sha, L; Shinkai, Y; Tsuchiya, Y; Unoki, T; Watanabe, Y1
Chi, G; Ding, Y; Ge, P; He, C; Lu, B; Lu, S; Luo, Y; Piao, M; Wang, C; Wang, X; Wang, Z1
Loganathan, C; Sakayanathan, P; Thayumanavan, P; Vijayan, S1
Ahmad, H; Baer, RW; Cox, JL; Crotts, MS; Jacobs, JC1
Lokesh, S; Numan, T; Shahriar, A; Timilsina, A; Yang, Y1

Reviews

1 review(s) available for cysteine and naphthoquinones

ArticleYear
The chemical biology of naphthoquinones and its environmental implications.
    Annual review of pharmacology and toxicology, 2012, Volume: 52

    Topics: Air Pollutants; Animals; Anti-Inflammatory Agents; Carcinogens; Cells, Cultured; Cysteine; Environment; Environmental Exposure; Glyceraldehyde-3-Phosphate Dehydrogenases; Humans; Naphthalenes; Naphthoquinones; Protein Tyrosine Phosphatase, Non-Receptor Type 1; Quinones; Reactive Oxygen Species

2012

Trials

1 trial(s) available for cysteine and naphthoquinones

ArticleYear
Effect of prolyl 4-hydroxylase inhibitor on fibroblast collagen production in vitro: an approach to the treatment of systemic sclerosis.
    The Journal of rheumatology, 1992, Volume: 19, Issue:11

    Topics: Blotting, Northern; Collagen; Cysteine; Enzyme-Linked Immunosorbent Assay; Fibroblasts; Fibronectins; Humans; Hydroxyproline; Naphthoquinones; Procollagen; Procollagen-Proline Dioxygenase; RNA, Messenger; Scleroderma, Systemic

1992

Other Studies

46 other study(ies) available for cysteine and naphthoquinones

ArticleYear
Polycyclic aromatic hydrocarbon (PAH) ortho-quinone conjugate chemistry: kinetics of thiol addition to PAH ortho-quinones and structures of thioether adducts of naphthalene-1,2-dione.
    Chemico-biological interactions, 1992, Sep-28, Volume: 84, Issue:2

    Topics: Benzopyrenes; Chromatography, High Pressure Liquid; Cysteine; Glutathione; Hydrogen-Ion Concentration; Kinetics; Magnetic Resonance Spectroscopy; Mercaptoethanol; Molecular Structure; Naphthoquinones; Polycyclic Compounds; Quinones; Sulfhydryl Compounds

1992
Characterization of purified, reconstituted site-directed cysteine mutants of the lactose permease of Escherichia coli.
    The Journal of biological chemistry, 1991, Aug-25, Volume: 266, Issue:24

    Topics: Amino Acid Sequence; Biological Transport; Cell Membrane; Cysteine; Dithiothreitol; Escherichia coli; Escherichia coli Proteins; Lactose; Membrane Potentials; Membrane Transport Modulators; Membrane Transport Proteins; Molecular Sequence Data; Monosaccharide Transport Proteins; Mutagenesis, Site-Directed; Naphthoquinones; Plasmids; Proteolipids; Symporters

1991
Fibrostatins, new inhibitors of prolyl hydroxylase. I. Taxonomy, isolation and characterization.
    The Journal of antibiotics, 1987, Volume: 40, Issue:9

    Topics: Chemical Phenomena; Chemistry, Physical; Cysteine; Fermentation; Naphthoquinones; Procollagen-Proline Dioxygenase; Spectrophotometry, Ultraviolet; Streptomyces

1987
Structures of fibrostatins, new inhibitors of prolyl hydroxylase.
    The Journal of antibiotics, 1987, Volume: 40, Issue:9

    Topics: Cysteine; Magnetic Resonance Spectroscopy; Models, Molecular; Naphthoquinones; Procollagen-Proline Dioxygenase; Streptomyces; Structure-Activity Relationship

1987
Inhibition of prolyl hydroxylase activity and collagen biosynthesis by fibrostatin C, a novel inhibitor produced by Streptomyces catenulae subsp. griseospora No. 23924.
    The Journal of antibiotics, 1988, Volume: 41, Issue:11

    Topics: Animals; Collagen; Cysteine; Estradiol; Female; Naphthoquinones; Procollagen-Proline Dioxygenase; Rats; Rats, Inbred Strains; Streptomyces

1988
Mechanisms of selective uptake of 2-methyl-4-naphthoquinol bis disodium phosphate, into some mammalian cells in tissue culture.
    British journal of cancer, 1973, Volume: 28, Issue:1

    Topics: Alkaline Phosphatase; Animals; Cattle; Cells; Cells, Cultured; Chloromercuribenzoates; Cysteine; Edetic Acid; Humans; Hydrogen-Ion Concentration; Kinetics; L Cells; Mice; Naphthoquinones; Neoplasms, Experimental; Phosphates; Tritium; Zinc

1973
Electron spin resonance studies of the chloranil-cysteine, dichlone-cysteine and dichlone-glutathione reactions.
    Biochimica et biophysica acta, 1967, Jun-13, Volume: 141, Issue:1

    Topics: Antifungal Agents; Cysteine; Electron Spin Resonance Spectroscopy; Glutathione; Naphthoquinones; Oxidation-Reduction; Quinones; Sulfhydryl Compounds

1967
Specificity of naphthoquinones as cofactor for NADPH oxidation by liver microsomes.
    Journal of biochemistry, 1967, Volume: 62, Issue:2

    Topics: Animals; Cysteine; In Vitro Techniques; Liver; Microsomes; NADP; Naphthoquinones; Oxidation-Reduction; Quinones; Rabbits; Spectrum Analysis; Stimulation, Chemical

1967
Reaction of tyrosine oxidation products with proteins of the lens.
    The Biochemical journal, 1968, Volume: 109, Issue:2

    Topics: Animals; Ascorbic Acid; Cataract; Catechol Oxidase; Cattle; Chemical Phenomena; Chemistry; Chromatography, Paper; Crystallins; Cysteine; Dihydroxyphenylalanine; Edetic Acid; Fluorescence; Iron; Naphthoquinones; Oxidation-Reduction; Proteins; Sulfates; Sulfur; Tyrosine

1968
Studies on the antibacterial and antifungal properties of 1, 4-naphthoquinones.
    British journal of pharmacology, 1970, Volume: 40, Issue:4

    Topics: Agar; Antifungal Agents; Bacteria; Candida; Cysteine; Densitometry; Enterococcus faecalis; Escherichia coli; Glutathione; Methods; Naphthoquinones; Oxygen Consumption; Polarography; Shigella sonnei; Spectrum Analysis; Staphylococcus; Ubiquinone; Ultraviolet Rays; Vitamin K

1970
Naphthoquinone inhibitors of Periplaneta americana and Scolytus multistriatus feeding: ultraviolet difference spectra of reactions of juglone, menadione, and 1,4-naphthoquinone with amino acids and the indicated mechanism of feeding inhibition.
    Chemico-biological interactions, 1971, Volume: 4, Issue:1

    Topics: Amino Acids; Animals; Chemical Phenomena; Chemistry; Chemoreceptor Cells; Cockroaches; Coleoptera; Cysteine; Feeding Behavior; Kinetics; Naphthoquinones; Protein Binding; Proteins; Spectrum Analysis; Structure-Activity Relationship; Ultraviolet Rays

1971
[Studies on inhibitors of cholesterol biosynthesis. II. Effects of benzoquinone and naphthoquinone derivatives on the incorporation of acetate-1-14C into cholesterol in rat liver homogenates].
    Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan, 1970, Volume: 90, Issue:4

    Topics: Acetates; Adenosine Triphosphate; Animals; Carbon Isotopes; Cholesterol; Cysteine; In Vitro Techniques; Liver; Male; Naphthoquinones; Oxidative Phosphorylation; Quinones; Rats; Vitamin K

1970
Effect of fibrostatin C, an inhibitor of prolyl 4-hydroxylase, on collagen secretion by human Tenon's capsule fibroblasts in vitro.
    Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie, 1996, Volume: 234 Suppl 1

    Topics: Aged; Cell Culture Techniques; Cell Division; Collagen; Connective Tissue; Connective Tissue Cells; Cysteine; Enzyme Inhibitors; Fibroblasts; Filtering Surgery; Glaucoma; Humans; Immunohistochemistry; Male; Naphthoquinones; Procollagen-Proline Dioxygenase; Wound Healing

1996
Selective inactivation of parvulin-like peptidyl-prolyl cis/trans isomerases by juglone.
    Biochemistry, 1998, Apr-28, Volume: 37, Issue:17

    Topics: Amino Acid Isomerases; Amino Acid Substitution; Circular Dichroism; Cysteine; Endopeptidases; Enzyme Activation; Enzyme Inhibitors; Escherichia coli; Escherichia coli Proteins; Fungal Proteins; Glutathione; Humans; Hydrolysis; Naphthoquinones; NIMA-Interacting Peptidylprolyl Isomerase; Peptidylprolyl Isomerase; Spectrophotometry; Sulfhydryl Compounds; Transcription Factors

1998
2-chloro-3-substituted-1,4-naphthoquinone inactivators of human cytomegalovirus protease.
    Bioorganic & medicinal chemistry letters, 1999, Oct-04, Volume: 9, Issue:19

    Topics: Binding Sites; Cell Line; Cysteine; Glutathione; Humans; Leukocyte Elastase; Molecular Structure; Naphthoquinones; Serine Endopeptidases; Serine Proteinase Inhibitors; Thrombin; Viral Plaque Assay

1999
Stimulation of topoisomerase II-mediated DNA damage via a mechanism involving protein thiolation.
    Biochemistry, 2001, Mar-20, Volume: 40, Issue:11

    Topics: Alanine; Alkylation; Animals; Cysteine; DNA Damage; DNA Topoisomerases, Type II; Drosophila; Humans; Intercalating Agents; KB Cells; Mutagenesis, Site-Directed; Naphthoquinones; Quinones; Sulfhydryl Compounds; Tumor Cells, Cultured; Vitamin K

2001
Interaction of camel lens zeta-crystallin with quinones: portrait of a substrate by fluorescence spectroscopy.
    Archives of biochemistry and biophysics, 2001, Nov-15, Volume: 395, Issue:2

    Topics: 2,6-Dichloroindophenol; Animals; Camelus; Catalysis; Crystallins; Cysteine; Dose-Response Relationship, Drug; Kinetics; Lens, Crystalline; Ligands; NADP; Naphthoquinones; Protein Binding; Spectrometry, Fluorescence

2001
Reduction of lapachones and their reaction with L-cysteine and mercaptoethanol on glassy carbon electrodes.
    Bioelectrochemistry (Amsterdam, Netherlands), 2002, May-15, Volume: 56, Issue:1-2

    Topics: Animals; Biosensing Techniques; Carbon; Cattle; Cysteine; DNA; Electrodes; Mercaptoethanol; Naphthoquinones; Oxidation-Reduction

2002
Stability of hemoglobin and albumin adducts of naphthalene oxide, 1,2-naphthoquinone, and 1,4-naphthoquinone.
    Toxicological sciences : an official journal of the Society of Toxicology, 2002, Volume: 68, Issue:2

    Topics: Albumins; Animals; Biotransformation; Cysteine; Dose-Response Relationship, Drug; Half-Life; Hemoglobins; Male; Models, Biological; Naphthalenes; Naphthoquinones; Protein Binding; Rats; Rats, Inbred F344; Time Factors

2002
[THE EFFECTS OF LUTEOSKYRIN, TOXIC SUBSTANCE FROM PENICILLIUM ISLANDICUM SOPP, ON THE SWELLING OF MITOCHONDRIA].
    The Japanese journal of experimental medicine, 1964, Volume: 34

    Topics: Adenosine Triphosphate; Anthraquinones; Benzoates; Calcium Chloride; Chloromercuribenzoates; Cysteine; Glutathione; Liver; Magnesium; Mercury; Mitochondria; Naphthoquinones; Pathology; Penicillium; Pharmacology; Phosphates; Rats; Research; Silver; Silver Compounds; Sucrose; Thyroxine; Toxicology

1964
A new approach to evaluating the extent of Michael adduct formation to PAH quinones: tetramethylammonium hydroxide (TMAH) thermochemolysis with GC/MS.
    Chemical research in toxicology, 2003, Volume: 16, Issue:11

    Topics: Animals; Anthraquinones; Benzoquinones; Cattle; Cysteine; Evaluation Studies as Topic; France; Gas Chromatography-Mass Spectrometry; Glutathione; Molecular Structure; Naphthoquinones; Polycyclic Aromatic Hydrocarbons; Quaternary Ammonium Compounds; Serum Albumin, Bovine

2003
Crystal structure of a bacterial type III polyketide synthase and enzymatic control of reactive polyketide intermediates.
    The Journal of biological chemistry, 2004, Oct-22, Volume: 279, Issue:43

    Topics: Acyltransferases; Asparagine; Aspartic Acid; Binding Sites; Catalysis; Catalytic Domain; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Codon; Crystallography, X-Ray; Cysteine; Escherichia coli; Evolution, Molecular; Hydrogen-Ion Concentration; Magnetic Resonance Spectroscopy; Models, Chemical; Models, Molecular; Mutagenesis, Site-Directed; Mutation; Naphthols; Naphthoquinones; Oxalic Acid; Polyketide Synthases; Protein Conformation; Protein Structure, Tertiary; Serine; Streptomyces; Streptomyces coelicolor

2004
Targeted mutagenesis of the Mycobacterium smegmatis mca gene, encoding a mycothiol-dependent detoxification protein.
    Journal of bacteriology, 2004, Volume: 186, Issue:18

    Topics: Amidohydrolases; Anti-Bacterial Agents; Bridged Bicyclo Compounds; Cysteine; Dinitrochlorobenzene; Disaccharides; Enzyme Inhibitors; Ethylmaleimide; Gene Deletion; Genes, Bacterial; Genetic Complementation Test; Glycopeptides; Inositol; Iodoacetamide; Mutagenesis, Insertional; Mycobacterium smegmatis; Mycobacterium tuberculosis; Naphthoquinones; Oxidants; Pyrazoles; Rifamycins; Streptomycin; Sulfhydryl Compounds; Vitamin K 3

2004
The 1,4-naphthoquinone scaffold in the design of cysteine protease inhibitors.
    Bioorganic & medicinal chemistry, 2007, Aug-01, Volume: 15, Issue:15

    Topics: Cathepsin B; Cysteine; Cysteine Proteinase Inhibitors; Models, Molecular; Molecular Structure; Naphthoquinones; Pancreatic Elastase; Papain

2007
Discovery of lactoquinomycin and related pyranonaphthoquinones as potent and allosteric inhibitors of AKT/PKB: mechanistic involvement of AKT catalytic activation loop cysteines.
    Molecular cancer therapeutics, 2007, Volume: 6, Issue:11

    Topics: Adenosine Triphosphate; Allosteric Regulation; Animals; Catalysis; Cell Line, Tumor; Cysteine; Down-Regulation; Enzyme Activation; Enzyme Inhibitors; Humans; Kinetics; Naphthoquinones; Phosphorylation; Protein Biosynthesis; Protein Kinases; Proto-Oncogene Proteins c-akt; Rats; RNA Caps; Structure-Activity Relationship; Substrate Specificity; Time Factors; TOR Serine-Threonine Kinases

2007
Juglone inactivates cysteine-rich proteins required for progression through mitosis.
    The Journal of biological chemistry, 2008, Aug-01, Volume: 283, Issue:31

    Topics: Animals; Cattle; Cell Cycle; CHO Cells; Cricetinae; Cricetulus; Cyclin B; Cyclin B1; Cysteine; Cytoplasm; Enzyme Inhibitors; Fibroblasts; Mice; Microtubules; Mitosis; Naphthoquinones

2008
Inactivation of the SMN complex by oxidative stress.
    Molecular cell, 2008, Jul-25, Volume: 31, Issue:2

    Topics: Amino Acid Sequence; Cross-Linking Reagents; Cyclic AMP Response Element-Binding Protein; Cysteine; Disulfides; Dithiothreitol; HeLa Cells; Humans; Molecular Sequence Data; Naphthoquinones; Nerve Tissue Proteins; Oxidation-Reduction; Oxidative Stress; Reactive Oxygen Species; Ribonucleoproteins, Small Nuclear; RNA-Binding Proteins; Sequence Alignment; Small Molecule Libraries; SMN Complex Proteins

2008
Ketosynthase III as a gateway to engineering the biosynthesis of antitumoral benastatin derivatives.
    Journal of biotechnology, 2009, Mar-10, Volume: 140, Issue:1-2

    Topics: Acyltransferases; Antineoplastic Agents; Cysteine; Escherichia coli; Glutathione Transferase; Mutation; Naphthacenes; Naphthoquinones; Point Mutation; Polyketide Synthases; Protein Binding; Protein Engineering; Protein Subunits; Substrate Specificity

2009
Pyranonaphthoquinone lactones: a new class of AKT selective kinase inhibitors alkylate a regulatory loop cysteine.
    Journal of medicinal chemistry, 2009, Apr-23, Volume: 52, Issue:8

    Topics: Alkylation; Antineoplastic Agents; Biomarkers; Cell Line, Tumor; Cell Proliferation; Cysteine; Humans; Lactones; Naphthoquinones; Oncogene Protein v-akt; Pyrans; Stereoisomerism; Structure-Activity Relationship

2009
Conjugates of plumbagin and phenyl-2-amino-1-thioglucoside inhibit MshB, a deacetylase involved in the biosynthesis of mycothiol.
    Bioorganic & medicinal chemistry, 2010, Apr-01, Volume: 18, Issue:7

    Topics: Acetylcysteine; Amidohydrolases; Bacterial Proteins; Cell Survival; Cysteine; Enzyme Inhibitors; Glycopeptides; Indicators and Reagents; Inositol; Mycobacterium tuberculosis; NADH, NADPH Oxidoreductases; Naphthoquinones; Oxidation-Reduction; Structure-Activity Relationship; Substrate Specificity; Thioglucosides

2010
Ghrelin suppression of Helicobacter pylori-induced S-nitrosylation-dependent Akt inactivation exerts modulatory influence on gastric mucin synthesis.
    Inflammopharmacology, 2011, Volume: 19, Issue:2

    Topics: Animals; Ascorbic Acid; Cells, Cultured; Cysteine; Enzyme Inhibitors; Epithelial Cells; Gastric Mucins; Gastric Mucosa; Ghrelin; Lipopolysaccharides; Naphthoquinones; NF-kappa B; Nitric Oxide; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type II; Phosphorylation; Protein Biosynthesis; Protein Kinase Inhibitors; Protein Processing, Post-Translational; Proto-Oncogene Proteins c-akt; Rats; Rats, Inbred Strains; S-Nitrosothiols; src-Family Kinases

2011
Inhibition of DNA binding activity of cAMP response element-binding protein by 1,2-naphthoquinone through chemical modification of Cys-286.
    Chemico-biological interactions, 2011, Jul-15, Volume: 192, Issue:3

    Topics: Cell Line, Tumor; Cyclic AMP Response Element-Binding Protein; Cysteine; Environmental Pollutants; Gene Expression; Gene Expression Regulation, Neoplastic; Humans; Mutagens; Naphthoquinones

2011
Topoisomerase I inactivation by a novel thiol reactive naphthoquinone.
    Biochemical and biophysical research communications, 2011, Jun-24, Volume: 410, Issue:1

    Topics: Cysteine; Dithiothreitol; DNA Topoisomerases, Type I; HeLa Cells; Humans; Naphthoquinones; Reducing Agents; Topoisomerase I Inhibitors

2011
Cysteine 81 is critical for the interaction of S100A4 and myosin-IIA.
    Biochemistry, 2011, Aug-23, Volume: 50, Issue:33

    Topics: cdc25 Phosphatases; Chromatography, Liquid; Cysteine; Cytoskeleton; Humans; Naphthoquinones; Nonmuscle Myosin Type IIA; Peptide Fragments; Protein Binding; Recombinant Proteins; S100 Calcium-Binding Protein A4; S100 Proteins; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization

2011
Redox cycling of 1,2-naphthoquinone by thioredoxin1 through Cys32 and Cys35 causes inhibition of its catalytic activity and activation of ASK1/p38 signaling.
    Chemical research in toxicology, 2012, Jun-18, Volume: 25, Issue:6

    Topics: Animals; Biocatalysis; Cell Death; Cell Survival; Cells, Cultured; Cysteine; MAP Kinase Kinase Kinase 5; Mice; Naphthoquinones; Oxidation-Reduction; p38 Mitogen-Activated Protein Kinases; Reactive Oxygen Species; Signal Transduction; Thioredoxins

2012
S-nitrosoglutathione covalently modifies cysteine residues of human carbonyl reductase 1 and affects its activity.
    Chemico-biological interactions, 2013, Feb-25, Volume: 202, Issue:1-3

    Topics: Alcohol Oxidoreductases; Amino Acid Sequence; Cysteine; Daunorubicin; Hexanones; Humans; Kinetics; Molecular Sequence Data; Naphthoquinones; Oxidation-Reduction; Pyridines; S-Nitrosoglutathione; Vitamin K 3

2013
Conformational preferences of plumbagin with phenyl-1-thioglucoside conjugates in solution and bound to MshB determined by aromatic association.
    Carbohydrate research, 2013, Apr-19, Volume: 371

    Topics: Amidohydrolases; Bacterial Proteins; Catalytic Domain; Crystallography, X-Ray; Cysteine; Enzyme Inhibitors; Glycopeptides; Inositol; Kinetics; Ligands; Molecular Conformation; Molecular Docking Simulation; Mycobacterium tuberculosis; Naphthoquinones; Protein Structure, Secondary; Superoxides; Thermodynamics; Thioglucosides

2013
Nitrosative stress and redox-cycling agents synergize to cause mitochondrial dysfunction and cell death in endothelial cells.
    Redox biology, 2013, Volume: 1

    Topics: Animals; Aorta; Cattle; Cell Death; Cells, Cultured; Cysteine; Drug Synergism; Endothelial Cells; Mitochondria; Naphthoquinones; Nitrosation; Reactive Oxygen Species; S-Nitrosothiols

2013
Glutathione-mediated reversibility of covalent modification of ubiquitin carboxyl-terminal hydrolase L1 by 1,2-naphthoquinone through Cys152, but not Lys4.
    Chemico-biological interactions, 2014, May-05, Volume: 214

    Topics: Blotting, Western; Cell Line, Tumor; Cysteine; Electrophoresis, Gel, Two-Dimensional; Glutathione; Humans; Lysine; Naphthoquinones; Recombinant Proteins; Ubiquitin Thiolesterase; Ubiquitination

2014
Reactive Sulfur Species-Mediated Activation of the Keap1-Nrf2 Pathway by 1,2-Naphthoquinone through Sulfenic Acids Formation under Oxidative Stress.
    Chemical research in toxicology, 2015, May-18, Volume: 28, Issue:5

    Topics: Cell Line, Tumor; Cysteine; Humans; Intracellular Signaling Peptides and Proteins; Kelch-Like ECH-Associated Protein 1; Naphthols; Naphthoquinones; NF-E2-Related Factor 2; Oxidative Stress; Signal Transduction; Sulfenic Acids; Sulfhydryl Compounds; Sulfur

2015
Details in the catalytic mechanism of mammalian thioredoxin reductase 1 revealed using point mutations and juglone-coupled enzyme activities.
    Free radical biology & medicine, 2016, Volume: 94

    Topics: Amino Acids; Catalysis; Cysteine; Humans; Mutation; NADPH Oxidases; Naphthoquinones; Oxidation-Reduction; Point Mutation; Selenocysteine; Substrate Specificity; Superoxides; Thioredoxin Reductase 1

2016
1,4-Naphthoquinone activates the HSP90/HSF1 pathway through the S-arylation of HSP90 in A431 cells: Negative regulation of the redox signal transduction pathway by persulfides/polysulfides.
    Free radical biology & medicine, 2017, Volume: 104

    Topics: Cell Line, Tumor; Cell Nucleus; Chromatography, Liquid; Cysteine; DNA-Binding Proteins; Gene Expression Regulation; Heat Shock Transcription Factors; HSP70 Heat-Shock Proteins; HSP90 Heat-Shock Proteins; Humans; Naphthoquinones; Oxidation-Reduction; Signal Transduction; Sulfhydryl Compounds; Sulfur; Tandem Mass Spectrometry

2017
RIP1 and RIP3 contribute to shikonin-induced glycolysis suppression in glioma cells via increase of intracellular hydrogen peroxide.
    Cancer letters, 2018, 07-01, Volume: 425

    Topics: Animals; Cell Line, Tumor; Cysteine; Gene Expression Regulation, Neoplastic; Glioma; Glutathione; Glycolysis; Humans; Hydrogen Peroxide; Mice; Naphthoquinones; Nuclear Pore Complex Proteins; Rats; Receptor-Interacting Protein Serine-Threonine Kinases; RNA-Binding Proteins; Xenograft Model Antitumor Assays

2018
Synthesis and Characterization of Plumbagin S-Allyl Cysteine Ester: Determination of Anticancer Activity In Silico and In Vitro.
    Applied biochemistry and biotechnology, 2022, Volume: 194, Issue:12

    Topics: Animals; Apoptosis; Cell Line, Tumor; Cysteine; Esters; Humans; Mice; Molecular Docking Simulation; Naphthoquinones

2022
Shikonin Causes Non-apoptotic Cell Death in B16F10 Melanoma.
    Anti-cancer agents in medicinal chemistry, 2023, Volume: 23, Issue:16

    Topics: Apoptosis; Cell Line, Tumor; Cysteine; Humans; Melanoma; Naphthoquinones; Necrosis; Reactive Oxygen Species

2023
Quantification of Quinones in Environmental Media by Chemical Tagging with Cysteine-Containing Peptides Coupled to Size Exclusionary Separation.
    Analytical chemistry, 2023, 08-29, Volume: 95, Issue:34

    Topics: Cysteine; Naphthoquinones; Oxidation-Reduction; Peptides; Quinones

2023