cysteine has been researched along with nadp in 280 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 112 (40.00) | 18.7374 |
| 1990's | 59 (21.07) | 18.2507 |
| 2000's | 59 (21.07) | 29.6817 |
| 2010's | 41 (14.64) | 24.3611 |
| 2020's | 9 (3.21) | 2.80 |
| Authors | Studies |
|---|---|
| Howell, SE; Lee, DJ; Libbey, LM; Pawlowski, NE; Schoenhard, GL; Sinnhuber, RO | 1 |
| Hiwatashi, A; Ichikawa, Y; Maruya, N; Yamano, T | 1 |
| Chang, GG; Hsu, RY | 1 |
| Labuc, GE; Madsen, NP | 1 |
| Comerio, G; Ferri, G; Iadarola, P; Speranza, ML; Zapponi, MC | 1 |
| Ramel, C; Rannug, U; Sundvall, A | 1 |
| Hiwatashi, A; Ichikawa, Y | 1 |
| Artigou, JY; Benhamou, JP; Descatoire, V; Pessayre, D; Wandscheer, JC | 1 |
| Iwakura, M; Katsuki, H; Tokushige, M | 1 |
| Flynn, TG; Shires, J; Walton, DJ | 1 |
| Clemons, EH; Gaetani, GD; Kirkman, HN; Mareni, C | 1 |
| Di Giorgio, RM; Macaione, S; Tucci, G | 1 |
| Farnden, KJ; Robertson, JG; Warburton, MP | 1 |
| Chrastil, J; Wilson, JT | 1 |
| Fulco, AJ; Hare, RS | 1 |
| Reitz, RC; Thompson, JA | 1 |
| Bollinger, JM; Booker, S; Holler, TP; Johnston, MI; Mao, SS; Stubbe, J; Yu, GX | 1 |
| Dallocchio, F; Hanau, S; Rippa, M | 1 |
| Murphy, ME; Scholich, H; Sies, H | 1 |
| Borhani, DW; Harter, TM; Petrash, JM | 1 |
| Araki, J; Masubuchi, Y; Narimatsu, S; Suzuki, T | 1 |
| Feix, JB; Kalyanaraman, B | 1 |
| Colman, RF; Smyth, GE | 1 |
| Kanofsky, JR; Sima, P | 1 |
| Brueggemeier, RW; Li, PK | 1 |
| Akman, SA; Block, JS; Chlebowski, RT; Dietrich, MF; Doroshow, JH | 1 |
| Cui, JY; Fukuyama, K; Matsubara, H; Wada, K; Wakabayashi, S | 1 |
| Mizutani, T | 1 |
| Ballou, DP; Distefano, MD; Massey, V; Miller, SM; Moore, MJ; Walsh, CT; Williams, CH | 1 |
| Hatefi, Y; Yamaguchi, M | 1 |
| Fischer, V; Mason, RP; Schreiber, J; Takahashi, N | 1 |
| Akman, SA; Block, JB; Chlebowski, R; Dietrich, M; Limberg, P | 1 |
| Köhler, H; Neupert, W; Nicholson, DW | 1 |
| Berden, JA; Hartog, AF; Persson, B; Rydström, J | 1 |
| Lindskog, S; Sanström, A | 1 |
| Alberta, JA; Fisher, RR; Modrak, DE; Wu, LN | 1 |
| Benson, RW; Hinson, JA; Potter, DW; Pumford, NR; Roberts, DW | 1 |
| López-Barea, J; Mata, AM; Pinto, MC | 1 |
| Kaiser, C; Lumper, L; Vogel, F; Witt, I | 1 |
| Kikuchi, G; Yoshida, T | 1 |
| Cavari, BZ; Grossowicz, N | 1 |
| Charles, AM; McCarthy, JT | 1 |
| Colman, RF | 1 |
| Henderson, PT; Thijssen, HH | 1 |
| Harding, JJ | 1 |
| Budowski, P; Sklan, D | 1 |
| Chung, AE; Edwards, DJ; Heinrikson, RL | 1 |
| Funaba, T; Izaki, K; Tashiro, Y | 1 |
| Thelander, L | 1 |
| Ishaque, A; Levy, HR; Milhausen, M | 1 |
| Chapman, JD; Greenstock, CL; Raleigh, JA; Reuvers, AP; Shiermen, E | 1 |
| Nicolas, JC | 1 |
| Sanderson, GW | 1 |
| Marks, PA | 1 |
| Rosalki, SB | 1 |
| Ewetz, L; Sörbo, B | 1 |
| Kerr, CT; Miller, RW | 1 |
| Hecker, E; Marks, F | 2 |
| Katoh, S; San Pietro, A | 1 |
| Field, JB; Oka, H | 1 |
| Nakai, N; Nishibayashi, H; Sato, R | 1 |
| Hosoi, K; Okinaka, S; Ozawa, E; Sugita, H | 1 |
| Braun, PE; Snell, EE | 1 |
| Aloj, E | 1 |
| Segel, IH; Woodin, TS | 1 |
| Domagk, GF; Schiwara, HW | 1 |
| Spolter, PD; Vogel, JM | 1 |
| Lumper, L; Zahn, H | 1 |
| Callaghan, P; Ebbon, GP | 1 |
| Bryan, JK | 1 |
| Blair, AH; Bodley, FH | 1 |
| Van Heyningen, R | 1 |
| Wills, ED | 2 |
| Audley, BG; Hepper, CM | 1 |
| Péron, FG; Tsang, CP | 1 |
| Fujiyama, T; Sasai, Y; Tanahashi, Y | 1 |
| Baliga, BS; Bhatnagar, GM; Jagannathan, V | 1 |
| Criss, WE; McKerns, KW | 1 |
| Chu, R; Colman, RF | 1 |
| Becker, RR; Howard, RL | 1 |
| Ball, P; Breuer, H | 1 |
| Juchau, MR; Krasner, J; Yaffe, SJ | 1 |
| Menzel, DB | 1 |
| Balinsky, D; Cleland, WW; Dennis, AW | 1 |
| Nicholas, DJ; Varma, AK | 1 |
| Schachet, M; Squire, PG | 1 |
| Rao, MR; Shailaja, MS | 1 |
| Hanley, HO; Williams, NJ; Wiseman, A | 1 |
| Williams, NJ; Wiseman, A | 1 |
| Ronchi, S; Williams, CH | 1 |
| Ellis, G; Goldberg, DM | 1 |
| Durner, K; Hildebrandt, W; Weide, H | 1 |
| Holland, P; Little, C | 1 |
| D'Auzac, J; Jacob, JL | 1 |
| Di Cola, D; Federici, G | 1 |
| Comerford, MJ; de Jongh, KS; Schofield, PJ | 1 |
| Haniu, M; Iyanagi, T; Legesse, K; Shively, JE | 1 |
| Baillie, TA; Dahlin, DC; Nelson, SD; Streeter, AJ | 1 |
| Alvaro, R; Fiorentini, KM; Lu, AY; West, SB; Wislocki, PG; Wolf, FJ | 1 |
| Holmgren, A; Lyckeborg, C | 1 |
| Fan, CC; Huennekens, FM; Vitols, KS | 1 |
| Krauth-Siegel, RL; Schirmer, I; Schirmer, RH; Untucht-Grau, R | 1 |
| Colman, RF; Johanson, RA | 2 |
| Ferri, G; Iadarola, P; Zapponi, MC | 1 |
| Hsieh, DP; Wan, NC | 1 |
| Iacobazzi, V; Palmieri, F; Stipani, I | 1 |
| Corcoran, GB; Horning, EC; Mitchell, JR; Vaishnav, YN | 1 |
| Bryant, DA; Golbeck, JH; Jung, YS; Vassiliev, IR; Yu, L | 1 |
| Hopkins, N; Williams, CH | 1 |
| Williams, CH | 1 |
| Bragg, PD; Glavas, NA; Hou, C | 1 |
| Bui, BT; Florentin, D; Izumi, Y; Marquet, A; Ohshiro, T; Yamamoto, M | 1 |
| Cook, RJ; Krupenko, SA; Wagner, C | 1 |
| Anderson, LE; Li, D; Schiffer, M; Stevens, FJ | 1 |
| Drijfhout, MC; Eppink, MH; Hagen, WR; van Berkel, WJ; van der Bolt, FJ | 1 |
| Chae, HZ; Chung, SJ; Rhee, SG | 1 |
| Chai, YC; Jung, CH; Thomas, JA | 1 |
| Maines, MD; McCoubrey, WK | 1 |
| Crétin, C; Decottignies, P; Gadal, P; Issakidis, E; Jacquot, JP; Miginiac-Maslow, M; Saarinen, M | 1 |
| Krishna, TS; Kuriyan, J; Waksman, G; Williams, CH | 1 |
| Accornero, P; Carrera, G; Curti, B; Vanoni, MA | 1 |
| Bhatnagar, A; Chakrabarti, B; Liu, SQ; Srivastava, SK; Ueno, N | 1 |
| Baillie, TA; Jochheim, CM | 1 |
| Kanofsky, JR; Sima, PD | 1 |
| Falzone, CJ; Iwakura, M; Jones, BE; Matthews, CR | 1 |
| Ansari, NH; Bhatnagar, A; Liu, SQ; Srivastava, SK | 1 |
| Björnstedt, M; Ericson, ML; Holmgren, A; Ren, X; Shen, B | 1 |
| Decottignies, P; Issakidis, E; Miginiac-Maslow, M | 1 |
| Aliverti, A; Curti, B; Herrmann, RG; Lübberstedt, T; Piubelli, L; Zanetti, G | 1 |
| Meighen, E; Smillie, L; Szittner, R; Vedadi, M | 1 |
| Cho, SW; Choi, SY; Hong, JW; Lee, SJ | 1 |
| Ameyibor, E; Fu, W; Gardet-Salvi, L; Johnson, MK; Knaff, DB; Schürmann, P; Staples, CR; Stritt-Etter, AL | 1 |
| Block, ER; Li, YD; Patel, JM; Zhang, JL | 1 |
| Bates, JN; Holmes, RW; Snyder, GD; Van Voorhis, BJ | 1 |
| Dabrowiak, JC; Goodisman, J; Hiort, C | 1 |
| Cullen, WR; Serves, SV; Styblo, M; Thomas, DJ | 1 |
| Gorren, AC; Mayer, B; Schmidt, K; Schrammel, A | 1 |
| Lee, H; Zhang, Y | 1 |
| Erickson, RR; Holtzman, JL; Zhou, L | 1 |
| Numazawa, M; Tachibana, M | 1 |
| Bragg, PD; Hou, C; Meuller, J; Rydström, J; Zhang, J | 1 |
| Mulrooney, SB; Williams, CH | 1 |
| Marrone, L; Viswanatha, T | 1 |
| Banditelli, S; Cappiello, M; Cecconi, I; Dal Monte, M; Del Corso, A; Moschini, R; Mura, U; Tsai, L; Vilardo, PG | 1 |
| Rao, GR; Sengupta, S; Subbarap Shaila, M | 1 |
| Mulrooney, SB; Veine, DM; Wang, PF; Williams, CH | 1 |
| Engst, S; Miller, SM | 1 |
| Gross, SS; Ikeda-Saito, M; Liu, Q; Martásek, P; Masters, BS; Migita, CT; Miller, RT; Raman, CS; Roman, LJ; Salerno, JC | 1 |
| Charrier, V; Claiborne, A; Luba, J | 1 |
| Anderson, WB; Colburn, NH; Gopalakrishna, R; Gundimeda, U; Slaga, TJ | 1 |
| Claiborne, A; Mallett, TC; Parsonage, D | 1 |
| Arscott, LD; Gilberger, TW; Müller, S; Wang, PF; Williams, CH | 1 |
| Ganago, AO; Golbeck, JH; Jung, YS; McIntosh, L; Schulz, R; Vassiliev, IR; Yu, J | 1 |
| Ludwig, ML; Marletta, MA | 1 |
| Ariño, A; Feyereisen, R; Guzov, VM; Murataliev, MB | 1 |
| Numazawa, M; Yamada, K | 1 |
| Poulsen, LL; Robertus, JD; Suh, JK; Ziegler, DM | 1 |
| de Laat, WT; Heijnen, JJ; van Gulik, WM; Vinke, JL | 1 |
| Arnér, ES; Holmgren, A; Zhong, L | 1 |
| Aubry, A; Branlant, G; Cobessi, D; Marchal, S; Tête-Favier, F | 1 |
| Barber, MJ; Pollock, VV | 1 |
| Ahvazi, B; Meighen, E; Szittner, R; Vrielink, A; Zhang, L | 1 |
| Fontecave, M; Mulliez, E; Padovani, D | 1 |
| Althage, M; Bizouarn, T; Rydström, J | 1 |
| Bazzi, MD | 1 |
| Ayene, IS; Biaglow, JE; Jenkins, SF; Koch, CJ; Mauldin, SK; Stamato, TD; Tuttle, SW | 1 |
| Maurizi, MR; Rasulova, F | 1 |
| González-Segura, L; Muñoz-Clares, RA; Velasco-García, R | 1 |
| Chae, HZ; Hwang, SC; Kang, SW; Kim, K; Rhee, SG; Woo, HA; Yang, KS | 1 |
| Johansson, C; Karlsson, BG; Pedersen, A; Rydström, J | 1 |
| Blanco, J; Kabaleeswaran, V; Moore, RA; Viola, RE | 1 |
| Berndt, KD; Chiaraluce, R; Consalvi, V; Ladenstein, R; Lebbink, JH | 1 |
| Raines, RT; Woycechowsky, KJ | 1 |
| Althage, M; Karlsson, J; Rydström, J | 1 |
| Jones, DP; Montfort, WR; Pohl, J; Powis, G; Reed, MS; Stuchlik, O; Watson, WH | 1 |
| Arscott, LD; Ballou, DP; Bauer, H; Massey, V; Schirmer, RH; Williams, CH | 1 |
| Munro, AW; Roitel, O; Scrutton, NS | 1 |
| Althage, M; Bill, RM; Gourdon, P; Karlsson, J; Levin, M; Rydström, J; Tigerström, A | 1 |
| Bischof, T; Flemming, D; Friedrich, T; Schlitt, A; Spehr, V | 1 |
| MARQUET, M | 1 |
| VILLANUEVA, JR | 1 |
| BEEVERS, L; FLESHER, D; HAGEMAN, RH | 1 |
| ELLIS, RJ | 1 |
| KOIDE, SS; TORRES, MT | 1 |
| ASANTE, GS; NEAL, AL | 1 |
| LEINWEBER, FJ; MONTY, KJ | 1 |
| YOSHIDA, A | 1 |
| EWETZ, L; SOERBO, B | 1 |
| ROBINSON, HC | 1 |
| BELCHER, RV; OWENS, CW | 1 |
| Leonardi, R; Roach, PL | 1 |
| Daff, S | 1 |
| Ghosh, D; Nakajin, S; Ohno, S; Sugiyama, T | 1 |
| Cho, SH; Choi, CY; Kim, BH; Kim, JH; Kim, JR; Kim, YD; Kwon, J; Lee, SM; Lee, SR | 1 |
| Cabral, DM; Landino, LM; Robinson, SH; Skreslet, TE | 1 |
| Green, J; Paget, MS | 1 |
| Kodaki, T; Makino, K; Watanabe, S | 1 |
| Kil, IS; Park, JW | 1 |
| Bergamini, CM; Cervellati, C; Cook, PF; Dallocchio, F | 1 |
| Arscott, LD; Ballou, DP; Becker, K; Davioud-Charvet, E; Deponte, M; Fritz-Wolf, K; Herold-Mende, C; Koncarevic, S; Meyer, M; Réau, R; Urig, S; Williams, CH | 1 |
| Abali, EE; Banerjee, D; Bertino, JR; Menon, LG; Mishra, PJ; Peters, R; Skacel, N | 1 |
| Fang, J; Holmgren, A; Lu, J | 1 |
| Carbone, V; Darmanin, C; El-Kabbani, O; Hara, A; Ishikura, S | 1 |
| Ding, H; Harrison, K; Lu, J | 1 |
| Carlson, L; Dwivedi, C; Guan, X; Herman, J; Peitz, G; Seefeldt, T; Zhang, Z | 1 |
| Katayama, A; Nagahara, N | 1 |
| Antikainen, NM; Benkovic, SJ; Hammes, GG; Smiley, RD | 1 |
| Clark, DD; Ensign, SA; Nocek, B; Pandey, AS; Peters, JW | 1 |
| González-Segura, L; Mújica-Jiménez, C; Muñoz-Clares, RA; Velasco-García, R; Zaldívar-Machorro, VJ | 1 |
| Kil, IS; Lee, YS; Park, JW; Shin, SW; Yeo, HS | 1 |
| Capitani, G; Glockshuber, R; Grütter, MG; Stirnimann, CU | 1 |
| Rhee, SG | 1 |
| Holton, JM; Hung, LW; Kim, SI; Park, MS; Pédelacq, JD; Rho, BS; Terwilliger, TC; Vigil, D | 1 |
| Arisaka, F; Fusada, N; Hara, S; Hisabori, T; Hosoya-Matsuda, N; Kikuchi, N; Motohashi, K; Romano, PG | 1 |
| Augusti, KT; Kumari, K | 1 |
| Burka, LT; Chen, LJ; DeRose, EF | 1 |
| Bayly, CI; Berthelette, C; Chauret, N; Crane, S; Day, S; Oballa, RM; Truchon, JF | 1 |
| Becker, K; Fritz-Wolf, K; Urig, S | 1 |
| Aizawa, S; Islam, MK; Kanamori, K; Kusaka, H; Michibata, H; Tsuboya, C; Ueki, T | 1 |
| Doe, I; Kawabata, A; Kubo, S; Kurokawa, Y; Masuko, T; Sekiguchi, F | 1 |
| Ilg, T; Jaeger, M; Rothacker, B | 1 |
| Elfarra, AA; Novick, RM | 1 |
| Bonner, A; Finlay, RM; Hamilton, CJ; Stewart, MJ | 1 |
| Chin, KH; Chou, SH; Liao, SJ; Wang, AH; Yang, CY | 1 |
| Böttcher, C; Glawischnig, E; Prade, E; Scheel, D; Schmotz, C; Westphal, L | 1 |
| Finnie, C; Shahpiri, A; Svensson, B | 1 |
| Dietz, KJ; Gärtner, F; Kandlbinder, A; Laxa, M; Muthuramalingam, M; Nunes de Miranda, SM; Seidel, T; Ströher, E | 1 |
| Dickert, F; Dobbek, H; Knauer, SH; Mende, S; Spiegelhauer, O; Ullmann, GM | 1 |
| Cejudo, FJ; Dietz, KJ; González, M; Guinea, M; Kirchsteiger, K; Pascual, MB; Pulido, P; Sahrawy, M; Sandalio, LM; Spínola, MC | 1 |
| Arnér, ES; Carvalho, CM; Holmgren, A; Lu, J; Zhang, X | 1 |
| Balendiran, GK; Cascio, D; Cuckovich, R; Ponniah, G; Sawaya, MR; Schwarz, FP; Verma, M | 1 |
| Muller, M | 1 |
| Beckerich, JM; Casaregola, S; Hébert, A | 1 |
| Du, J; King, I; Nassar, AE | 1 |
| Battistuzzi, G; Bellei, M; Cowan, JA; Mansy, SS; Sola, M; Wu, SP | 1 |
| Díaz-Sánchez, AG; González-Segura, L; Lira-Rocha, A; Muñoz-Clares, RA; Rudiño-Piñera, E; Torres-Larios, A | 1 |
| Chibani, K; Gualberto, JM; Jacquot, JP; Rey, P; Rouhier, N; Tarrago, L; Wingsle, G | 1 |
| Altschmied, J; Haendeler, J; Matsushima, S; Sadoshima, J; Shao, D; Zschauer, TC | 1 |
| Kil, IS; Park, JW; Shin, SW | 1 |
| Arvidsson, PI; Besidski, Y; Bueters, T; Bylund, J; Macsari, I; Olofsson, S; Petersson, C | 1 |
| Fryszkowska, A; Gardiner, JM; Mansell, D; Scrutton, NS; Stephens, G; Toogood, HS | 1 |
| Hwang, S; Kim, S; Lazar, P; Lee, KO; Lee, KW; Lee, SY; Lee, Y; Moon, JC; Shon, Y; Thangapandian, S | 1 |
| Krupenko, SA; Malakhau, Y; Strickland, KC; Tsybovsky, Y | 1 |
| Du, F; Li, X; Liu, Z; Xing, J | 1 |
| Cai, Y; Cheng, A; Han, X; Lou, H; Sun, Y; Wu, Y; Xu, R; Yu, H | 1 |
| Bothner, B; Grieco, PA; Hamerly, T; Heinemann, J; Hilmer, JK; Maaty, WS; Movahed, N; Peters, JW; Reeves, BD; Steffens, JD; Therien, J | 1 |
| Cheung, A; Dusi, RG; Francois, P; Hamilton, CJ; Kolar, SL; Liu, GY; Posada, AC; Roberts, AA | 1 |
| Hugo, M; Messens, J; Radi, R; Reyes, AM; Trujillo, M; Van Laer, K; Vertommen, D | 1 |
| Arnér, ES; Cebula, M; Holmgren, A; Johansson, K; Lundberg, JO; Pader, I; Sengupta, R; Xu, J | 1 |
| Brewer, GJ; Ghosh, D | 1 |
| Bomati, EK; Bowman, ME; Dixon, RA; Dudareva, N; Louie, GV; Mühlemann, JK; Noel, JP; Pan, H; Wang, X; Zhou, R | 1 |
| Amâncio, S; Carvalho, L; Guiu-Aragonés, C; Martin-Hernandez, AM; Vidigal, P | 1 |
| Chen, W; Chen, Z; Guan, X; Jiang, Z; Lin, N; Zhang, X; Zheng, Z | 1 |
| Isom, CE; Karr, EA; Lessner, DJ; McCarver, AC; Sheehan, R | 1 |
| Du, Y; Holmgren, A; Ioannou, PV; Lu, J; Ren, X; Zhang, X; Zheng, Y | 1 |
| Bárcena, JA; González, R; López-Grueso, MJ; Muntané, J; Padilla, CA | 1 |
| Bartels, D; Chandrasekar, B; Mohammed, S; Stiti, N; Strubl, L; van der Hoorn, RA | 1 |
| Arnér, ESJ; Benhar, M; Engelman, R; Ziv, T | 1 |
| Crespo, JL; Lemaire, SD; Pérez-Pérez, ME | 1 |
| Bathke, J; Becker, K; Brandstädter, C; Burkhardt, A; Fritz-Wolf, K; Jortzik, E; Rahlfs, S | 1 |
| Alvarez, HM; Dávila Costa, JS; Leichert, L; Silva, RA | 1 |
| Gladyshev, VN; Manta, B | 1 |
| Dai, Y; Haque, MM; Stuehr, DJ | 1 |
| Arefieva, TI; Krasnikova, TL; Pylaeva, EA; Sidorova, MV | 1 |
| Grüber, G; Kumar, A; Subramanian Manimekalai, MS | 1 |
| Chaiyen, P; Maenpuen, S; Munkajohnpong, P; Phonbuppha, J; Tinikul, R | 1 |
| Cho, HJ; Cho, HY; Huh, TL; Kang, BS; Kwon, OS; Lee, HS; Park, JW | 1 |
| Duangkaew, P; Feix, J; Kim, JP; Kotewong, R; Rongnoparut, P; Shen, AL; Xia, C | 1 |
| Lin, H; Wang, M; Zhang, Y | 1 |
| Braun, J; Czabany, T; Jung, J; Nidetzky, B | 1 |
| Delfarah, A; Graham, NA; Joly, JH; Parrish, S; Phung, PS | 1 |
| Cao, HY; Chen, XL; Chen, Y; Li, CY; Li, PY; Su, HN; Wang, P; Wang, Y; Wang, YJ; Zhang, Y; Zhang, YZ | 1 |
| Campbell, AC; LeBlanc, S; Nam, HG; Schuermann, JP; Sobrado, P; Sultana, N; Tanner, JJ; Valentino, H | 1 |
| Gudim, I; Hammerstad, M; Hersleth, HP | 1 |
| Aliverti, A; de Rosa, M; Nonnis, S | 1 |
| Fraaije, MW; Mascotti, ML; Partipilo, M; Slotboom, DJ; Wijma, HJ; Yang, G | 1 |
| Hou, W; Lu, R; Wang, D; Wang, P; Zhao, S; Zhao, W; Zhao, X | 1 |
9 review(s) available for cysteine and nadp
| Article | Year |
|---|---|
Glucose-6-phosphate dehydrogenase in mature erythrocytes.
Topics: Ascorbic Acid; Carbohydrate Metabolism; Cysteine; Erythrocyte Aging; Erythrocytes; Glucosephosphate Dehydrogenase; Hemolysis; Humans; NADP; Pentosephosphates; Pyruvates | 1967 |
[Chemistry and biochemistry of disulfide exchanges].
Topics: Amino Acid Sequence; Chemical Phenomena; Chemistry; Cysteine; Cystine; Free Radicals; Glutathione; Hydrogen-Ion Concentration; Kinetics; Membranes; Mercaptoethanol; Mitochondria; NADP; Proteins; Sulfhydryl Compounds; Sulfur Isotopes; Thioglycolates; Vasopressins | 1965 |
Glutathione reductase from human erythrocytes: amino-acid sequence of the structurally known FAD-binding domain.
Topics: Amino Acid Sequence; Binding Sites; Cysteine; Dihydrolipoamide Dehydrogenase; Erythrocytes; Flavin-Adenine Dinucleotide; Glutathione Reductase; Humans; NADP; Phosphates; Protein Conformation; Trypsin | 1981 |
Mechanism and structure of thioredoxin reductase from Escherichia coli.
Topics: Catalysis; Cysteine; Dihydrolipoamide Dehydrogenase; Disulfides; Escherichia coli; Flavin-Adenine Dinucleotide; Flavoproteins; Glutathione Reductase; NADP; Oxidation-Reduction; Oxidoreductases; Protein Structure, Tertiary; Structure-Activity Relationship; Thioredoxin-Disulfide Reductase | 1995 |
A new decoration for nitric oxide synthase - a Zn(Cys)4 site.
Topics: Animals; Arginine; Binding Sites; Biopterins; Citrulline; Cysteine; Dimerization; Electron Transport; Macromolecular Substances; Models, Molecular; NADP; Nitric Oxide; Nitric Oxide Synthase; Oxidation-Reduction; Protein Conformation; Zinc | 1999 |
Bacterial redox sensors.
Topics: Bacteria; Bacterial Proteins; Benzoquinones; Cysteine; Flavin Mononucleotide; Flavin-Adenine Dinucleotide; Hemeproteins; Iron-Sulfur Proteins; NAD; NADP; Oxidation-Reduction; Oxidative Stress; Signal Transduction | 2004 |
nDsbD: a redox interaction hub in the Escherichia coli periplasm.
Topics: Amino Acid Motifs; Cysteine; Cystine; Dimerization; Electron Transport; Enzyme Activation; Escherichia coli; Escherichia coli Proteins; Hydrogen Bonding; Models, Molecular; NADP; Oxidation-Reduction; Oxidoreductases; Periplasm; Periplasmic Proteins; Protein Conformation; Protein Disulfide Reductase (Glutathione); Protein Disulfide-Isomerases; Protein Interaction Mapping; Protein Structure, Tertiary; Structure-Activity Relationship; Thioredoxins | 2006 |
Interacting with thioredoxin-1--disease or no disease?
Topics: Animals; Atherosclerosis; Blood Vessels; Cardiovascular System; Cysteine; Cystine; Diabetes Mellitus, Type 2; Heart Diseases; Humans; Hydrogen Peroxide; Mice; Models, Cardiovascular; Molecular Targeted Therapy; Myocardium; NADP; Neoplasm Proteins; Neoplasms; Oxidation-Reduction; Peroxiredoxins; Reactive Oxygen Species; Signal Transduction; Thioredoxins | 2013 |
Regulated methionine oxidation by monooxygenases.
Topics: Adaptor Proteins, Signal Transducing; Animals; Cysteine; Cytoskeletal Proteins; Humans; Isoenzymes; Kinetics; LIM Domain Proteins; Methionine; Methionine Sulfoxide Reductases; Microfilament Proteins; Mixed Function Oxygenases; Models, Molecular; NADP; Oxidation-Reduction; Protein Domains; Protein Processing, Post-Translational; Protein Structure, Secondary; Reactive Oxygen Species | 2017 |
271 other study(ies) available for cysteine and nadp
| Article | Year |
|---|---|
Aflatoxin B1 metabolism to aflatoxicol and derivatives lethal to Bacillus subtilis GSY 1057 by rainbow trout (Salmo gairdneri) liver.
Topics: Aflatoxins; Animals; Bacillus subtilis; Cysteine; Cytosine; In Vitro Techniques; Liver; Microsomes, Liver; NADP; Salmonidae; Trout | 1976 |
Properties of crystalline reduced nicotinamide adenine dinucleotide phosphate-adrenodoxin reductase from bovine adrenocortical mitochondria. II. Essential histidyl and cysteinyl residues at the NADPH binding site of NADPH-adrenodoxin reductase.
Topics: Adrenal Cortex; Adrenal Glands; Adrenodoxin; Animals; Binding Sites; Cattle; Cysteine; Diethyl Pyrocarbonate; Ferredoxin-NADP Reductase; Glutathione; Histidine; Hydrogen-Ion Concentration; Hydroxylamines; Light; Methylene Blue; Mitochondria; NAD; NADH, NADPH Oxidoreductases; NADP | 1976 |
Mechanism of pigeon liver malic enzyme: kinetics, specificity, and half-site stoichiometry of the alkylation of a cysteinyl residue by the substrate-inhibitor bromopyruvate.
Topics: Affinity Labels; Alkylation; Animals; Binding Sites; Cations, Divalent; Columbidae; Cysteine; Hydrogen-Ion Concentration; Kinetics; Liver; Malate Dehydrogenase; NADP; Pyruvates; Spectrum Analysis; Sulfhydryl Reagents; Temperature | 1977 |
Inhibition by 3'-methyl-4-dimethylamino-azobenzene of in vitro cell-free protein synthesis: possible involvement of an electrophilic metabolite.
Topics: Aminopyrine N-Demethylase; Aniline Hydroxylase; Animals; Cell-Free System; Cysteine; Depression, Chemical; Glutathione; In Vitro Techniques; Leucine; Liver; Male; Methyldimethylaminoazobenzene; NADP; Oxidoreductases; p-Dimethylaminoazobenzene; Phenobarbital; Polyethylene Glycols; Protein Biosynthesis; Rats | 1977 |
Subunit structure and activity of glyceraldehyde-3-phosphate dehydrogenase from spinach chloroplasts.
Topics: Amino Acids; Chloroplasts; Cysteine; Glyceraldehyde-3-Phosphate Dehydrogenases; Iodoacetates; Macromolecular Substances; Molecular Weight; NAD; NADP; Peptide Fragments; Plants; Tetrathionic Acid | 1978 |
The mutagenic effect of 1,2-dichloroethane on Salmonella typhimurium I. Activation through conjugation with glutathion in vitro.
Topics: Animals; Cysteine; Ethylene Dichlorides; Glutathione; Hydrocarbons, Chlorinated; In Vitro Techniques; Liver; Male; Mutagens; NADP; Rats; Salmonella typhimurium; Subcellular Fractions | 1978 |
Crystalline reduced nicotinamide adenine dinucleotide phosphate-adrenodoxin reductase from pig adrenocortical mitochondria. Essential histidyl and cysteinyl residues of the NADPH-binding site and environment of the adrenodoxin-binding site.
Topics: Adrenal Cortex; Adrenodoxin; Animals; Binding Sites; Cattle; Cysteine; Diethyl Pyrocarbonate; Ferredoxin-NADP Reductase; Ferredoxins; Histidine; Mitochondria; NADH, NADPH Oxidoreductases; NADP; Sulfhydryl Reagents; Swine | 1978 |
Formation and inactivation of a chemically reactive metabolite of vinyl chloride.
Topics: Animals; Cysteine; Cytochrome P-450 Enzyme System; DDT; Epoxide Hydrolases; Epoxy Compounds; Glutathione; Hydrocarbons, Chlorinated; Male; Microsomes, Liver; NADP; Phenobarbital; Proadifen; Protein Binding; Rats; Vinyl Chloride; Vinyl Compounds | 1979 |
Studies on regulatory functions of malic enzymes. VII. Structural and functional characteristics of sulfhydryl groups in NADP-linked malic enzyme from Escherichia coli W.
Topics: Cysteine; Dithionitrobenzoic Acid; Escherichia coli; Ethylmaleimide; Kinetics; Magnesium; Malate Dehydrogenase; NADP; Spectrophotometry, Ultraviolet; Sulfhydryl Reagents; Thermodynamics | 1979 |
Properties of the nicotinamide adenine dinucleotide phosphate-dependent aldehyde reductase from pig kidney. Amino acid composition, reactivity of cysteinyl residues, and stereochemistry of D-glyceraldehyde reduction.
Topics: Aldehyde Oxidoreductases; Amino Acids; Animals; Binding Sites; Circular Dichroism; Cysteine; Electrophoresis, Disc; Glyceraldehyde; Hydrogen-Ion Concentration; Kidney; Kinetics; Mercaptoethanol; Mercuribenzoates; NADP; Protein Binding; Protein Conformation; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet; Swine | 1975 |
Red cell NADP+ and NADPH in glucose-6-phosphate dehydrogenase deficiency.
Topics: Black People; Cysteine; Erythrocytes; Glucosephosphate Dehydrogenase Deficiency; Hexosephosphates; Humans; Italy; Jews; Male; Mediterranean Islands; NADP; North Carolina; Pentosephosphates; Sodium Hydroxide | 1975 |
Cysteine oxidase activity in rat retina during development.
Topics: Aging; Amino Acid Oxidoreductases; Animals; Cysteine; Female; Male; Mitochondria; NAD; NADP; Rats; Retina; Sulfinic Acids; Taurine | 1975 |
Induction of glutamate synthase during nodule development in lupin.
Topics: Amino Acids; Ammonium Chloride; Ammonium Sulfate; Chromatography, Gel; Cysteine; Enzyme Induction; Glutamate Synthase; Glutamate-Ammonia Ligase; Glutamates; Glycine; Microscopy, Electron; NAD; NADP; Oxidation-Reduction; Plant Physiological Phenomena; Plants; Rhizobium; Sodium; Sulfates; Time Factors; Transaminases | 1975 |
4-Nitrocatechol production from rho-nitrophenol by rat liver.
Topics: Adenosine Triphosphate; Animals; Catechols; Chromatography, Thin Layer; Cysteine; In Vitro Techniques; Microsomes, Liver; NADP; Nitro Compounds; Nitrophenols; Organ Specificity; Rats; Sulfhydryl Compounds; Time Factors | 1975 |
Carbon monoxide and hydroxymercuribenzoate sensitivity of a fatty acid (omega-2) hydroxylase from Bacillus megaterium.
Topics: Bacillus megaterium; Carbon Monoxide; Cysteine; Cytochrome P-450 Enzyme System; Ferredoxins; Glutathione; Hydroxymercuribenzoates; Kinetics; Mixed Function Oxygenases; NADP; Oxidation-Reduction; Oxygen; Palmitic Acids | 1975 |
Studies on the mechanism of the NADPH-catalyzed peroxidation of endogenous microsomal lipid.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Chelating Agents; Cysteine; Diphosphates; Dithiothreitol; Enzyme Activation; Glutathione; Kinetics; Lipids; Male; Microsomes, Liver; NADP; Oxidation-Reduction; Peroxidases; Phosphates; Protein Binding; Rats; Time Factors | 1975 |
A model for the role of multiple cysteine residues involved in ribonucleotide reduction: amazing and still confusing.
Topics: Base Sequence; Circular Dichroism; Cysteine; Epitopes; Kinetics; Molecular Sequence Data; NADP; Nucleotides; Oxidation-Reduction; Ribonucleoside Diphosphate Reductase; Ribonucleotides; Thioredoxin-Disulfide Reductase; Thioredoxins | 1992 |
Subunits asymmetry in the ternary complex of lamb liver 6-phosphogluconate dehydrogenase detected by a NADP analogue.
Topics: Animals; Binding Sites; Cysteine; Gluconates; Liver; Lysine; NADP; Phosphogluconate Dehydrogenase; Protein Conformation; Sheep | 1992 |
Protection by glutathione and other thiol compounds against the loss of protein thiols and tocopherol homologs during microsomal lipid peroxidation.
Topics: Adenosine Diphosphate; Animals; Ascorbic Acid; Cysteine; Dithioerythritol; Glutathione; Iron; Lipid Peroxidation; Luminescent Measurements; Microsomes, Liver; NADP; Rats; Sulfhydryl Compounds; Thioctic Acid; Vitamin E | 1992 |
The crystal structure of the aldose reductase.NADPH binary complex.
Topics: Aldehyde Reductase; Amino Acid Sequence; Binding Sites; Cloning, Molecular; Cysteine; Escherichia coli; Humans; Models, Molecular; Mutagenesis, Site-Directed; NADP; Oxidation-Reduction; Protein Conformation; Recombinant Proteins; Serine | 1992 |
Metabolic activation of lidocaine and covalent binding to rat liver microsomal protein.
Topics: Animals; Biotransformation; Carbon Monoxide; Cysteine; Cytochrome P-450 Enzyme System; Debrisoquin; Dose-Response Relationship, Drug; Female; Glutathione; Lidocaine; Male; Microsomes, Liver; NADP; Oxygen; Proadifen; Propranolol; Proteins; Quinidine; Rats; Rats, Inbred Strains | 1992 |
An electron spin resonance study of merocyanine 540-mediated type I reactions in liposomes.
Topics: Cysteine; Electron Spin Resonance Spectroscopy; Glutathione; Liposomes; NADP; Oxidation-Reduction; Pyrimidinones; Radiation-Sensitizing Agents; Structure-Activity Relationship | 1991 |
Cysteinyl peptides of pig heart NADP-dependent isocitrate dehydrogenase that are modified upon inactivation by N-ethylmaleimide.
Topics: Amino Acid Sequence; Animals; Chromatography, High Pressure Liquid; Cysteine; Ethylmaleimide; Isocitrate Dehydrogenase; Molecular Sequence Data; Myocardium; NADP; Peptide Mapping; Swine; Trypsin | 1991 |
Singlet oxygen production from the reactions of ozone with biological molecules.
Topics: Antioxidants; Ascorbic Acid; Cysteine; Free Radicals; Histidine; Luminescent Measurements; Methionine; NAD; NADP; Ozone; Solvents; Uric Acid | 1991 |
7-substituted 1,4,6-androstatriene-3,17-diones as enzyme-activated irreversible inhibitors of aromatase.
Topics: Androstatrienes; Androstenedione; Aromatase; Aromatase Inhibitors; Binding, Competitive; Cysteine; Enzyme Activation; In Vitro Techniques; Kinetics; Microsomes; NADP; Placenta | 1990 |
Synergistic cytotoxicity between menadione and dicumarol vs. murine leukemia L1210.
Topics: Adenosine Triphosphate; Animals; Antineoplastic Combined Chemotherapy Protocols; Calcium; Cell Division; Cysteine; Dicumarol; Drug Synergism; Glutathione; Leukemia L1210; Mice; NADP; Oxidation-Reduction; Oxygen Consumption; Quinones; Vitamin K | 1987 |
Isolation and sequence studies of cysteinyl peptides from Spirulina glutathione reductase: comparison of active site cysteine peptides with those of other flavoprotein disulfide oxidoreductases.
Topics: Amino Acid Sequence; Amino Acids; Binding Sites; Cyanobacteria; Cysteine; Disulfides; Flavoproteins; Glutathione Reductase; Molecular Sequence Data; NADP; Oxidoreductases; Peptides | 1989 |
Some evidence of the enzymatic conversion of bovine suppressor phosphoseryl-tRNA to selenocysteyl-tRNA.
Topics: Amino Acids; Animals; Cattle; Chromatography, Thin Layer; Cysteine; Glutathione; NADP; RNA, Transfer; RNA, Transfer, Amino Acyl; Selenium; Selenocysteine; Transferases | 1989 |
Evidence for the participation of Cys558 and Cys559 at the active site of mercuric reductase.
Topics: Binding Sites; Cysteine; Disulfides; Dithionite; Dithiothreitol; Escherichia coli; Kinetics; NADP; Oxidoreductases; Protein Binding; Spectrophotometry | 1989 |
Mitochondrial nicotinamide nucleotide transhydrogenase: NADPH binding increases and NADP binding decreases the acidity and susceptibility to modification of cysteine-893.
Topics: Animals; Cattle; Cysteine; Ethylmaleimide; Hydrogen-Ion Concentration; In Vitro Techniques; Kinetics; Mitochondria; NADH, NADPH Oxidoreductases; NADP; NADP Transhydrogenases; Substrate Specificity | 1989 |
An ESR study of nonenzymatic reactions of nitroso compounds with biological reducing agents.
Topics: Acetylcysteine; Chemical Phenomena; Chemistry; Cysteine; Electron Spin Resonance Spectroscopy; Glutathione; NADP; Naphthalenesulfonates; Nitroso Compounds; Oxidation-Reduction | 1988 |
Modulation of cytotoxicity of menadione sodium bisulfite versus leukemia L1210 by the acid-soluble thiol pool.
Topics: Animals; Cysteine; Dose-Response Relationship, Drug; Glutathione; Kinetics; Leukemia L1210; Mice; NADP; Oxidation-Reduction; Superoxides; Vitamin K; Vitamin K 3 | 1985 |
Import of cytochrome c into mitochondria. Cytochrome c heme lyase.
Topics: Chromatography, High Pressure Liquid; Cysteine; Cytochrome c Group; Ethylmaleimide; Heme; Hemin; Lyases; Mitochondria; Models, Molecular; NAD; NADP; Neurospora crassa; Peptide Fragments; Protein Conformation; Reticulocytes; Trypsin | 1987 |
NBD-Cl modification of essential residues in mitochondrial nicotinamide nucleotide transhydrogenase from bovine heart.
Topics: 4-Chloro-7-nitrobenzofurazan; Animals; Cattle; Chemical Phenomena; Chemistry; Cysteine; Kinetics; Lysine; Mitochondria, Heart; NAD; NADH, NADPH Oxidoreductases; NADP; NADP Transhydrogenases; Oxadiazoles; Photochemistry; Spectrometry, Fluorescence; Spectrophotometry; Sulfhydryl Compounds | 1988 |
Rapid-scan stopped-flow studies of the flavoenzyme mercuric reductase during catalytic turnover.
Topics: Catalysis; Cysteine; Models, Theoretical; NADP; Oxidation-Reduction; Oxidoreductases; Pseudomonas aeruginosa | 1988 |
Conformational features of bovine heart mitochondrial transhydrogenase.
Topics: Animals; Binding Sites; Cattle; Cross-Linking Reagents; Cysteine; Dithionitrobenzoic Acid; Dithiothreitol; Ethylmaleimide; In Vitro Techniques; Mitochondria, Heart; NADH, NADPH Oxidoreductases; NADP; NADP Transhydrogenases; Protein Conformation; Sulfhydryl Reagents | 1988 |
A sensitive immunochemical assay for acetaminophen-protein adducts.
Topics: Acetaminophen; Animals; Cysteine; Enzyme-Linked Immunosorbent Assay; Liver; Mathematics; Methods; Mice; Microsomes, Liver; NADP; Protein Binding; Proteins; Rabbits | 1987 |
Redox interconversion of glutathione reductase from Escherichia coli. A study with pure enzyme and cell-free extracts.
Topics: Bacterial Proteins; Cysteine; Dithiothreitol; Enzyme Activation; Escherichia coli; Ferricyanides; Glutathione; Glutathione Reductase; Molecular Weight; NAD; NADP; Oxidation-Reduction; Oxygen | 1985 |
NADPH-cytochrome P-450 reductase (pig liver). Studies on the sequence of the cyanogen bromide peptides from the catalytic domain and on the reactivity of the thiol groups.
Topics: Amino Acid Sequence; Animals; Catalysis; Chemical Phenomena; Chemistry; Cyanogen Bromide; Cysteine; Liver; NADP; NADPH-Ferrihemoprotein Reductase; Peptide Fragments; Structure-Activity Relationship; Swine | 1985 |
Significance of the glycine cleavage system in glycine and serine catabolism in avian liver.
Topics: Ammonium Chloride; Animals; Arylformamidase; Bicarbonates; Carbon Dioxide; Carbon Isotopes; Chickens; Columbidae; Cycloserine; Cysteine; Enzyme Activation; Folic Acid; Glycine; Hydroxylamines; Hypoxanthines; L-Serine Dehydratase; Liver; Male; Mitochondria, Liver; NAD; NADP; Oxidoreductases; Pyridoxal Phosphate; Rats; Rats, Inbred Strains; Semicarbazides; Serine; Species Specificity; Subcellular Fractions; Transferases; Uric Acid | 1971 |
Properties of homoserine dehydrogenase in a thermophilic bacterium.
Topics: Alcohol Oxidoreductases; Bacillus; Cations, Monovalent; Chromatography, DEAE-Cellulose; Culture Media; Cysteine; Drug Stability; Enzyme Repression; Feedback; Homoserine; Hot Temperature; Hydrogen-Ion Concentration; Kinetics; NAD; NADP; Potassium; Spectrophotometry, Ultraviolet; Threonine | 1973 |
Studies on isocitrate lyase from the facultative autotroph Thiobacillus novellus.
Topics: Adenine Nucleotides; Buffers; Cell-Free System; Culture Media; Cysteine; Dipeptides; Electrophoresis, Polyacrylamide Gel; Glutathione; Glyoxylates; Hydrogen-Ion Concentration; Isocitrate Dehydrogenase; Isocitrates; Magnesium; NADP; Oxo-Acid-Lyases; Phosphates; Spectrophotometry; Succinates; Thiobacillus; Ultrafiltration | 1973 |
A glutamyl residue in the active site of triphosphopyridine nucleotide-dependent isocitrate dehydrogenase of pig heart.
Topics: Amides; Animals; Aspartic Acid; Binding Sites; Carbodiimides; Carbon Radioisotopes; Carboxy-Lyases; Catalysis; Cysteine; Drug Synergism; Glutamates; Glycine; Isocitrate Dehydrogenase; Isocitrates; Ketoglutaric Acids; Kinetics; Manganese; Morpholines; Myocardium; NADP; Swine; Temperature; Tyrosine | 1973 |
Interference of the reduction of p-nitrobenzoate in E. coli by nitrofurantoin.
Topics: Benzoates; Cysteine; Escherichia coli; Kinetics; NAD; NADP; Nitrate Reductases; Nitro Compounds; Nitrofurantoin; Oxidation-Reduction; Spectrophotometry; Spectrophotometry, Ultraviolet; Time Factors | 1973 |
Altered heat-lability of a fraction of glutathione reductase in aging human lens.
Topics: Adult; Aged; Aging; Cysteine; Electrophoresis, Polyacrylamide Gel; Electrophoresis, Starch Gel; Glucosephosphate Dehydrogenase; Glutathione Reductase; Hot Temperature; Humans; Lens, Crystalline; Middle Aged; NADP; Phosphoglycerate Kinase | 1973 |
Desaturation and saturation of fatty acids by sheep rumen bacteria: optimal conditions and cofactor requirements.
Topics: Aerobiosis; Anaerobiosis; Animals; Bacteria; Buffers; Carbon Radioisotopes; Chromatography, Gas; Chromatography, Thin Layer; Cysteine; Fatty Acids; Hydrogen-Ion Concentration; Hydrogenation; Linoleic Acids; Male; Methylene Blue; NAD; NADP; Oleic Acids; Oxidation-Reduction; Phosphates; Rumen; Sheep; Sucrose; Temperature | 1974 |
Triphosphopyridine nucleotide specific isocitrate dehydrogenase from Azotobacter vinelandii. Alkylation of a specific methionine residue and amino acid sequence of the peptide containing this residue.
Topics: Alkylation; Amino Acid Sequence; Amino Acids; Carbon Radioisotopes; Chemical Phenomena; Chemistry; Chromatography, Gel; Chromatography, Ion Exchange; Cyanogen Bromide; Cysteine; Iodoacetates; Isocitrate Dehydrogenase; Lysine; Malates; Methionine; NADP; Peptide Fragments; Protein Denaturation; Structure-Activity Relationship; Thiocyanates; Tritium; Trypsin; Urea | 1974 |
Mechanism of mercuric chloride resistance in microorganisms. 3. Purification and properties of a mercuric ion reducing enzyme from Escherichia coli bearing R factor.
Topics: Ammonium Sulfate; Apoproteins; Chromatography, DEAE-Cellulose; Chromatography, Gel; Chromatography, Thin Layer; Cysteine; D-Amino-Acid Oxidase; Dithiothreitol; Drug Resistance, Microbial; Escherichia coli; Extrachromosomal Inheritance; Flavin Mononucleotide; Flavin-Adenine Dinucleotide; Glutathione; Mercaptoethanol; Mercury; NADP; Spectrophotometry | 1974 |
Reaction mechanism of ribonucleoside diphosphate reductase from Escherichia coli. Oxidation-reduction-active disulfides in the B1 subunit.
Topics: Benzoates; Binding Sites; Chromatography, Paper; Cysteine; Cystine; Disulfides; Electron Transport; Escherichia coli; Flavoproteins; Guanidines; Kinetics; Macromolecular Substances; Molecular Weight; NADP; Nitro Compounds; Oxidation-Reduction; Protein Binding; Protein Conformation; Ribonucleotide Reductases; Spectrophotometry, Ultraviolet; Sulfhydryl Compounds; Tritium | 1974 |
On the absence of cysteine in glucose 6-phosphate dehydrogenase from Leuconostoc mesenteroides.
Topics: Amino Acids; Benzoates; Binding Sites; Chromatography, Ion Exchange; Crystallization; Cysteine; Disulfides; Electrophoresis, Polyacrylamide Gel; Glucosephosphate Dehydrogenase; Guanidines; Hydroxyapatites; Leuconostoc; Macromolecular Substances; Molecular Weight; NADP; Nitro Compounds; Protein Binding; Protein Conformation; Sulfhydryl Compounds; Time Factors | 1974 |
Competitive radioprotection and radiosensitization in chemical systems.
Topics: Acetophenones; Ascorbic Acid; Binding, Competitive; Cyclic N-Oxides; Cysteamine; Cysteine; Dithiothreitol; DNA; Ethylmaleimide; Histamine; Metronidazole; NAD; NADP; Nitro Compounds; Nitrobenzenes; Nitrofurantoin; Nitrofurazone; Nitrophenols; Oxygen; Paraquat; Promethazine; Pyridinium Compounds; Quinones; Radiation Effects; Radiation-Protective Agents; Radiation-Sensitizing Agents; Tetrazolium Salts; Vitamin K | 1974 |
Purification of an enzyme containing a NADP-protected cysteine on organomercuri-agarose 17beta-estradiol dehydrogenase.
Topics: Chromatography, Affinity; Cysteine; Estradiol; Hydroxysteroid Dehydrogenases; Mercury; NADP; Organometallic Compounds; Sepharose | 1974 |
5-Dehydroshikimate reductase in the tea plant (Camellia sinensis L.). Properties and distribution.
Topics: Alcohol Oxidoreductases; Chloromercuribenzoates; Cysteine; Enzymes; Flavonoids; Hydrogen-Ion Concentration; In Vitro Techniques; NADP; Shikimic Acid; Tea | 1966 |
An improved procedure for serum creatine phosphokinase determination.
Topics: Adenine Nucleotides; Adenosine Triphosphate; Chemical Phenomena; Chemistry; Colorimetry; Creatine Kinase; Cysteine; Humans; Muscular Diseases; NADP; Spectrophotometry; Temperature | 1967 |
Characteristics of the cysteinesulfinate-forming enzyme system in rat liver.
Topics: Animals; Catalysis; Cysteine; Enzymes; Hydroxylamines; Iron; Liver; Microsomes; Mitochondria; NADP; Rats; Sulfinic Acids; Sulfur Isotopes | 1966 |
Soluble NADP-linked dihydroorotate dehydrogenase from a pseudomonad.
Topics: Cysteine; Cytochromes; Dialysis; Edetic Acid; Electrophoresis; Fluorometry; Myocardium; NADP; Orotic Acid; Oxidation-Reduction; Oxidoreductases; Pseudomonas; Solubility; Spectrophotometry; Sulfides | 1967 |
[On the metabolism and mechanism of action of estrogens. 8. The biogenesis and metabolism of 2-hydroxyestrone in relation to the formation of protein-bound and water soluble estrone metabolites and to NADPH oxidation in rat liver microsomes].
Topics: Aminopterin; Animals; Carbon Isotopes; Cysteine; Estrone; Female; Folic Acid; Glutathione; Humans; Kinetics; Liver; Male; Microsomes; NADP; Oxidation-Reduction; Phenylalanine; Phosphates; Protein Binding; Pteridines; Rats; Steroids | 1966 |
Ascorbate-supported NADP photoreduction by heated Euglena chloroplasts.
Topics: Ascorbic Acid; Chloroplasts; Cysteine; Electron Transport; Euglena; Hot Temperature; Kinetics; Light; Models, Biological; NADP; Oxidation-Reduction; Spectrophotometry; Temperature | 1967 |
Inhibition of rat liver nicotinamide adenine dinucleotide kinase by reduced nicotinamide adenine dinucleotide phosphate.
Topics: Animals; Benzoates; Carbon Isotopes; Cellulose; Chromatography, Ion Exchange; Cysteine; Kinetics; Liver; Mercaptoethanol; NAD; NADP; Phosphotransferases; Rats | 1968 |
Specificity of naphthoquinones as cofactor for NADPH oxidation by liver microsomes.
Topics: Animals; Cysteine; In Vitro Techniques; Liver; Microsomes; NADP; Naphthoquinones; Oxidation-Reduction; Quinones; Rabbits; Spectrum Analysis; Stimulation, Chemical | 1967 |
Comparison of various methods for the determination of serum creatine phosphokinase.
Topics: Adenosine Triphosphate; Creatine Kinase; Cysteine; Humans; Methods; NAD; NADP; Phosphates; Spectrophotometry | 1967 |
Biosynthesis of sphingolipid bases. II. Keto intermediates in synthesis of sphingosine and dihydrosphingosine by cell-free extracts of Hansenula ciferri.
Topics: Amino Alcohols; Ascomycota; Autoradiography; Carbon Isotopes; Cell-Free System; Chemical Phenomena; Chemistry; Chromatography, Thin Layer; Coenzyme A; Crystallization; Cysteine; Ketones; Models, Biological; NADP; Palmitic Acids; Serine; Stimulation, Chemical | 1968 |
The oxygen requirement of an NADH dehydrogenase from Sepia officinalis.
Topics: Animals; Chemical Phenomena; Chemistry; Cysteine; Cystine; Ferrocyanides; Glutathione; Iron; Mollusca; NAD; NADP; Optic Lobe, Nonmammalian; Oxidoreductases; Oxygen; Phenanthrolines; Tectum Mesencephali | 1968 |
Glutathione reductase-dependent metabolism of cysteine-S-sulfate by Penicillium chrysogenum.
Topics: Cell-Free System; Cysteine; Electrophoresis; Glutathione Reductase; Kinetics; Models, Biological; NADP; Penicillium; Spectrophotometry; Sulfates; Sulfides; Sulfur; Time Factors | 1968 |
[Degradation of deoxysurgars by bacterial enzymes. V. Purification and characterization of an NADP-dependent abequose dehydrogenase from Pseudomonas putida].
Topics: Arabinose; Chemical Phenomena; Chemistry; Chloromercuribenzoates; Cysteine; Galactose; Glutathione; Hexoses; Hydrogen-Ion Concentration; Kinetics; NADP; Oxidoreductases; Pseudomonas; Ribose; Stereoisomerism; Thioglycolates | 1968 |
Rat-liver thiol: protein-disulphide oxidoreductase.
Topics: Animals; Ascorbic Acid; Binding Sites; Buffers; Cesium; Cysteine; Drug Stability; Edetic Acid; Glutathione; Glutathione Reductase; Insulin; Iodine Isotopes; Kinetics; Liver; Manganese; Mercaptoethanol; Models, Chemical; NADP; Rats; Sulfhydryl Compounds; Thioctic Acid | 1968 |
The conversion of S-n-propyl-L-cysteine into its sulphoxide by microsomal preparations from rat liver.
Topics: Animals; Cysteine; Edetic Acid; Electrophoresis; In Vitro Techniques; Liver; Microsomes; NAD; NADP; Rats; Sulfoxides; Sulfur Isotopes | 1968 |
Studies on the catalytic and regulatory properties of homoserine dehydrogenase of Zea mays roots.
Topics: Alcohol Oxidoreductases; Aminobutyrates; Aspartic Acid; Binding Sites; Cysteine; Hydroxybutyrates; Kinetics; NAD; NADP; Plants; Serine; Zea mays | 1969 |
Human liver aldehyde dehydrogenase: partial purification and properties.
Topics: Aldehydes; Arsenic; Chloromercuribenzoates; Chromatography, Gel; Chromatography, Ion Exchange; Cysteine; Disulfiram; Humans; Hydrogen-Ion Concentration; Liver; Mercaptoethanol; Mercury; Molecular Weight; NAD; NADP; Oxidoreductases; Sulfhydryl Compounds; Thiocarbamates | 1969 |
The metabolism of D-glyceraldehyde by the lens.
Topics: Animals; Anti-Bacterial Agents; Autoradiography; Buffers; Carbon Isotopes; Cattle; Color; Crystallins; Cysteine; Fluorescence; Fructose; Glucose; Glutathione; Glyceraldehyde; Glyceric Acids; Glycerol; In Vitro Techniques; Isomerases; Lactates; Lens, Crystalline; NADP; Phosphates; Phosphotransferases; Rabbits; Rats; Species Specificity; Sulfhydryl Compounds | 1969 |
Lipid peroxide formation in microsomes. General considerations.
Topics: Animals; Ascorbic Acid; Bile Acids and Salts; Chloromercuribenzoates; Cysteine; Electron Transport; Ethylmaleimide; Ferredoxins; Ferricyanides; Glutathione; In Vitro Techniques; Lipid Metabolism; Liver; Male; Metals; Microsomes; NADP; Oxygen Consumption; Peroxides; Rats | 1969 |
Lipid peroxide formation in microsomes. Relationship of hydroxylation to lipid peroxide formation.
Topics: Aminopyrine; Animals; Carbon Tetrachloride; Chloroform; Chloromercuribenzoates; Codeine; Cysteine; Ethylmaleimide; Glutathione; In Vitro Techniques; Lipid Metabolism; Microsomes; NAD; NADP; Oxidation-Reduction; Peroxides; Rats | 1969 |
Th biosynthesis of rubber from beta-hydroxy-beta-methylgluarylcoenzyme A in Hevea brasiliensis latex.
Topics: Adenosine Triphosphate; Alcohol Oxidoreductases; Carbon Isotopes; Centrifugation; Coenzyme A; Cysteine; Glutarates; Glutathione; Kinetics; Lyases; Mevalonic Acid; NAD; NADP; Rubber; Seasons | 1969 |
Further studies on corticosteroidogenesis. VI. Pyruvate and malate supported steroid 11-beta-hydroxylation in rat adrenal gland mitochondria.
Topics: Adenosine Triphosphate; Adrenal Glands; Animals; Arsenic; Corticosterone; Cysteine; Depression, Chemical; Desoxycorticosterone; Dinitrophenols; Electron Transport; Fluorometry; Isocitrate Dehydrogenase; Malate Dehydrogenase; Malates; Mitochondria; NAD; NADP; Nucleotides; Oxaloacetates; Oxidoreductases; Oxygen Consumption; Polarography; Pyruvates; Rats; Stimulation, Chemical | 1969 |
Histochemical study of oxidative enzymes and cysteine desulfurase in familiar benign chronic pemphigus and Darier's disease.
Topics: Chronic Disease; Coenzymes; Cysteine; Darier Disease; Glucosephosphate Dehydrogenase; Histocytochemistry; Humans; Lyases; NADP; Oxidoreductases; Pemphigus; Skin; Succinate Dehydrogenase | 1969 |
Metabolism and mechanism of action of oestrogens. XII. Structure and mechanism of formation of water-soluble and protein-bound metabolites of oestrone in rat-liver microsomes in vitro and in vivo.
Topics: Amines; Animals; Carbon Isotopes; Chromatography, Thin Layer; Cysteine; Estranes; Estrone; Female; Glutathione; Liver; Male; Mercaptoethanol; Microsomes; NADP; Protein Binding; Quinones; Rats; Solubility; Sulfhydryl Compounds; Thioglycolates; Thiouracil; Tritium | 1969 |
Nicotinamide adenine dinucleotide phosphate-specific glycerol dehydrogenase of Aspergillus niger.
Topics: Acetone; Alcohol Oxidoreductases; Aspergillus; Chloromercuribenzoates; Cysteine; Diphosphates; Glycerol; Hydrogen-Ion Concentration; Kinetics; NADP; Ultracentrifugation | 1964 |
Studies on ACTH-induced changes at the NADP+-binding site of bovine adrenal glucose 6-phosphate dehydrogenase.
Topics: Adrenal Glands; Adrenocorticotropic Hormone; Amino Acids; Animals; Barium; Benzoates; Binding Sites; Cattle; Chelating Agents; Chloromercuribenzoates; Cysteine; Detergents; Drug Stability; Edetic Acid; Glucosephosphate Dehydrogenase; Guanidines; Hexosephosphates; Iodoacetates; Magnesium; NAD; NADP; Phenanthrolines; Spectrophotometry; Sulfhydryl Compounds; Time Factors; Urea | 1969 |
The role of sulfhydryl groups in the catalytic function of isocitrate dehydrogenase. 3. Effect of N-ethylmaleimide on chemical and physical properties.
Topics: Amino Acids; Animals; Antigens; Benzoates; Binding Sites; Carbon Isotopes; Chemical Phenomena; Chemistry; Chromatography, Gel; Chromatography, Paper; Cysteine; Ethylmaleimide; Immune Sera; Immunodiffusion; Isocitrate Dehydrogenase; Kinetics; Manganese; Methionine; Myocardium; NADP; Optical Rotatory Dispersion; Peptide Hydrolases; Protein Denaturation; Rabbits; Succinates; Sulfhydryl Compounds; Sulfides; Swine; Time Factors | 1970 |
Isolation and some properties of the triphosphopyridine nucleotide isocitrate dehydrogenase from Bacillus stearothermophilus.
Topics: Amino Acids; Bacillus; Buffers; Chemical Phenomena; Chemistry; Chloromercuribenzoates; Cysteine; Edetic Acid; Electrophoresis, Disc; Guanidines; Hot Temperature; Hydrogen-Ion Concentration; Isocitrate Dehydrogenase; Kinetics; Magnesium; Manganese; Molecular Weight; NADP; Tetroses; Thermodynamics; Ultracentrifugation; Urea | 1970 |
[Purification and characterization of a cytoplasmic 17-hydroxysteroid: NAD(P)-oxidoreductase from rabbit liver].
Topics: Amides; Animals; Chemical Phenomena; Chemistry; Chloromercuribenzoates; Chromatography, Gel; Chromatography, Ion Exchange; Chromatography, Paper; Chromatography, Thin Layer; Copper; Cysteine; Cytoplasm; Edetic Acid; Estradiol; Hydroxysteroid Dehydrogenases; Kinetics; Liver; Magnesium; NADP; Rabbits; Zinc | 1970 |
Model systems for aromatic nitro group reduction--relationships to tissue catalyzed reagents.
Topics: Aminobenzoates; Animals; Benzoates; Biological Transport, Active; Blood; Carbon Monoxide; Cysteine; Dialysis; Electrons; Female; Flavin Mononucleotide; Flavin-Adenine Dinucleotide; Glutathione; Humans; Hydrogen-Ion Concentration; In Vitro Techniques; Indicators and Reagents; Liver; Male; Mice; Models, Biological; NAD; NADP; Oxidation-Reduction; Placenta; Pregnancy; Rats; Tissue Extracts | 1970 |
Oxidation of biologically active reducing substances by ozone.
Topics: Ascorbic Acid; Chemical Phenomena; Chemistry; Cysteine; Glutathione; Kinetics; NAD; NADP; Oxidation-Reduction; Ozone; Papain; Thioglycolates | 1971 |
Kinetic and isotope-exchange studies on shikimate dehydrogenase from Pisum sativum.
Topics: Alcohol Oxidoreductases; Buffers; Calcium Phosphates; Carbon Isotopes; Chemical Precipitation; Chromatography, DEAE-Cellulose; Cysteine; Dialysis; Drug Stability; Feedback; Kinetics; Mathematics; Methods; NADP; Plants; Quaternary Ammonium Compounds; Shikimic Acid; Sulfates | 1971 |
Metabolism of 35 S-sulphate and properties of APS-kinase and PAPS-reductase in Nitrobacter agilis.
Topics: Adenosine Triphosphate; Anaerobiosis; Chromatography; Cysteine; Dimercaprol; Glutathione; Homocysteine; Hydrogen-Ion Concentration; Magnesium; Methionine; Molecular Weight; NADP; Nitrobacter; Nucleosides; Nucleotidyltransferases; Oxygen; Phosphotransferases; Sulfates; Sulfides; Sulfites; Sulfur; Sulfur Isotopes; Taurine | 1971 |
Bovine adrenal glucose-6-phosphate dehydrogenase. 3. Control of the activity by ascorbate, substrates, and hydrophobic molecules.
Topics: Adrenal Glands; Alcohols; Animals; Ascorbic Acid; Cattle; Chromatography, Gel; Cysteine; Dialysis; Drug Stability; Enzyme Activation; Free Radicals; Glucosephosphate Dehydrogenase; Hydrogen Peroxide; Ketones; Mercaptoethanol; Molecular Weight; NADP; Serum Albumin, Bovine; Solubility; Time Factors | 1971 |
Homoserine dehydrogenases of Serratia marcescens S a -3.
Topics: Alcohol Oxidoreductases; Cysteine; Enzyme Repression; Escherichia coli; Homoserine; Isoleucine; Methionine; NAD; NADP; Neurospora; Phosphotransferases; Salmonella typhimurium; Serratia marcescens; Threonine | 1971 |
Decreased thermal stability of alcohol dehydrogenase in the presence of oxidized nicotinamide-adenine dinucleotide or oxidized nicotinamide-adenine dinucleotide phosphate.
Topics: Alcohol Oxidoreductases; Animals; Cysteine; Hot Temperature; Liver; NAD; NADP; Protein Denaturation; Saccharomyces; Serum Albumin, Bovine | 1971 |
Thermal inactivation of alcohol dehydrogenases in the presence of NAD + or NADP + .
Topics: Alcohol Oxidoreductases; Animals; Cattle; Cysteine; Drug Stability; Ethanol; Horses; Hot Temperature; Liver; NAD; NADP; Protein Binding; Protein Conformation; Serum Albumin, Bovine; Time Factors; Yeasts | 1971 |
The isolation and primary structure of a peptide containing the oxidation-reduction active cystine of Escherichia coli thioredoxin reductase.
Topics: Amino Acid Sequence; Amino Acids; Bacterial Proteins; Binding Sites; Chromatography, Gel; Chromatography, Ion Exchange; Cysteine; Cystine; Disulfides; Electron Transport; Escherichia coli; Flavin-Adenine Dinucleotide; Maleimides; Molecular Weight; NADP; Oxidation-Reduction; Oxidoreductases; Pepsin A; Peptides; Sulfhydryl Compounds; Thiocyanates | 1972 |
Automation of a kinetic spectrophotometric assay for ATP: creatine phosphotransferase activity suitable for human serum and muscle extracts.
Topics: Autoanalysis; Creatine Kinase; Cysteine; Dithiothreitol; Enzyme Activation; Female; Glucosephosphate Dehydrogenase; Glutathione; Glutathione Reductase; Humans; Male; Mercaptoethanol; Methods; Muscles; NADP; Spectrophotometry; Ultraviolet Rays | 1972 |
[Comparative studies on the activation determination of some enzymes in yeast strains following growth on n-alkanes].
Topics: Alcohol Oxidoreductases; Alkanes; Aspartate Aminotransferases; Candida; Citric Acid Cycle; Cysteine; Edetic Acid; Enzyme Activation; Glutamate Dehydrogenase; Hydrogen-Ion Concentration; Isocitrate Dehydrogenase; Lyases; Mitosporic Fungi; NAD; NADP; Phenylhydrazines; Quaternary Ammonium Compounds | 1972 |
Sulfhydril groups and the concerted inhibition of NADP + -linked isocitrate dehydrogenase.
Topics: Animals; Binding Sites; Carboxy-Lyases; Cysteine; Drug Synergism; Ethylmaleimide; Glyoxylates; Isocitrate Dehydrogenase; Ketoglutaric Acids; Myocardium; NADP; Oxaloacetates; Oxidation-Reduction; Radiation Effects; Structure-Activity Relationship; Sulfhydryl Compounds; Swine | 1972 |
[Glyceraldehyde-3-phosphate dehydrogenase from the latex of Hevea brasiliensis. Comparative study with its phosphorylating homologue].
Topics: Acetamides; Adenine Nucleotides; Binding, Competitive; Calcium; Centrifugation, Density Gradient; Chromatography, Gel; Citrates; Cysteine; Electrophoresis, Polyacrylamide Gel; Glyceraldehyde; Glyceraldehyde-3-Phosphate Dehydrogenases; Glyceric Acids; Iodoacetates; Macromolecular Substances; Magnesium; Molecular Weight; NAD; NADP; Organophosphorus Compounds; Plants; Rubber; Structure-Activity Relationship; Trees | 1972 |
Effect of physiological reducing compounds on the inactivation of tyrosine aminotransferase from guinea-pig liver.
Topics: Animals; Cysteamine; Cysteine; Dithiothreitol; Glutathione; Guinea Pigs; In Vitro Techniques; Liver; Male; Mercaptoethanol; Microsomes, Liver; NADP; Oxidation-Reduction; Tyrosine Transaminase | 1982 |
Comparative inhibition profiles of human brain and mouse liver L-hexonate dehydrogenase.
Topics: Animals; Brain; Carbohydrate Dehydrogenases; Chloromercuribenzoates; Copper; Copper Sulfate; Cysteine; Dose-Response Relationship, Drug; Humans; Iodoacetates; Iodoacetic Acid; Liver; Mercuric Chloride; Mercury; Mice; NADP; p-Chloromercuribenzoic Acid | 1983 |
Structural analysis of NADPH-cytochrome P-450 reductase from porcine hepatic microsomes. Sequences of proteolytic fragments, cysteine-containing peptides, and a NADPH-protected cysteine peptide.
Topics: Amino Acid Sequence; Amino Acids; Animals; Chromatography, High Pressure Liquid; Cysteine; Electrophoresis, Polyacrylamide Gel; Glutathione Reductase; Microsomes, Liver; Molecular Weight; NADP; NADPH-Ferrihemoprotein Reductase; Peptide Fragments; Rabbits; Rats; Swine; Trypsin | 1984 |
The covalent binding of acetaminophen to protein. Evidence for cysteine residues as major sites of arylation in vitro.
Topics: Acetaminophen; Amino Acids; Animals; Benzoquinones; Caseins; Cysteine; Glutathione; Imines; Male; Mice; Mice, Inbred BALB C; Microsomes, Liver; NADP; Phenobarbital; Proteins; Serum Albumin, Bovine | 1984 |
Drug residue formation from ronidazole, a 5-nitroimidazole. I. Characterization of in vitro protein alkylation.
Topics: Alkylation; Animals; Chromatography, High Pressure Liquid; Cysteine; Female; Male; Microsomes, Liver; Muscles; NAD; NADP; NADPH-Ferrihemoprotein Reductase; Nitroimidazoles; Nucleic Acids; Nucleotides; Protein Binding; Rats; Ronidazole; Swine | 1982 |
Enzymatic reduction of alloxan by thioredoxin and NADPH-thioredoxin reductase.
Topics: Alloxan; Bacterial Proteins; Cysteine; Cystine; NADH, NADPH Oxidoreductases; NADP; Oxidation-Reduction; Thioredoxin-Disulfide Reductase; Thioredoxins | 1980 |
Inhibition of dihydrofolate reductase by methotrexate: a new look at an old problem.
Topics: Animals; Catalysis; Cells, Cultured; Cysteine; Folic Acid Antagonists; Histidine; Kinetics; Leukemia L1210; Methotrexate; Mice; NADP; Structure-Activity Relationship | 1980 |
Cysteine in the manganous-isocitrate binding site of pig heart TPN-specific isocitrate dehydrogenase. II. Identification of a critical cysteine-containing tryptic peptide derived from the thiocyano enzyme.
Topics: Amino Acids; Animals; Binding Sites; Cyanides; Cysteine; Dithionitrobenzoic Acid; Isocitrate Dehydrogenase; Isocitrates; Manganese; Myocardium; NADP; Peptide Fragments; Potassium Cyanide; Swine; Trypsin | 1981 |
Cysteine in the manganous-isocitrate binding site of pig heart TPN-specific isocitrate dehydrogenase. I. Kinetics of chemical modification and properties of thiocyano enzyme.
Topics: Animals; Binding Sites; Cysteine; Dithionitrobenzoic Acid; Dose-Response Relationship, Drug; Isocitrate Dehydrogenase; Isocitrates; Kinetics; Manganese; Myocardium; NADP; Nitrobenzoates; Potassium Cyanide; Swine | 1981 |
Chloroplast glyceraldehyde-3-phosphate dehydrogenase (NADP+). Reactivity of essential cysteine residues in holo- and apoenzyme.
Topics: Apoenzymes; Apoproteins; Chloroplasts; Cysteine; Glyceraldehyde-3-Phosphate Dehydrogenases; Iodoacetates; Iodoacetic Acid; Kinetics; NAD; NADP; Peptide Fragments; Plants; Trypsin | 1981 |
Enzymatic formation of the bisfuran structure in aflatoxin biosynthesis.
Topics: Aflatoxins; Anthraquinones; Aspergillus; Chemical Phenomena; Chemistry; Cysteine; Dichlorvos; Dithiothreitol; NADP; Oxygen; Pigments, Biological | 1980 |
[Relationship between cysteinesulfinate and aspartate transport in mitochondria].
Topics: Animals; Ascorbic Acid; Aspartic Acid; Biological Transport; Cysteine; Isomerism; Mitochondria, Liver; NADP; Neurotransmitter Agents; Oxidation-Reduction; Oxygen Consumption; Rats; Sulfinic Acids | 1980 |
Evidence that acetaminophen and N-hydroxyacetaminophen form a common arylating intermediate, N-acetyl-p-benzoquinoneimine.
Topics: Acetaminophen; Animals; Ascorbic Acid; Benzoquinones; Cysteine; Imines; In Vitro Techniques; Microsomes, Liver; Mixed Function Oxygenases; NADP; Oxidation-Reduction; Rats | 1980 |
Modified ligands to FA and FB in photosystem I. II. Characterization of a mixed ligand [4Fe-4S] cluster in the C51D mutant of PsaC upon rebinding to P700-Fx cores.
Topics: Aspartic Acid; Chlorophyll; Cloning, Molecular; Cyanobacteria; Cysteine; Electron Spin Resonance Spectroscopy; Electron Transport; Escherichia coli; Freezing; Iron-Sulfur Proteins; Kinetics; Ligands; Macromolecular Substances; Membrane Proteins; Mutagenesis, Site-Directed; NADP; Oxidation-Reduction; Photochemistry; Photosystem I Protein Complex; Point Mutation; Proteins; Recombinant Proteins; Spectrophotometry; Thermodynamics; Time Factors | 1995 |
Lipoamide dehydrogenase from Escherichia coli lacking the redox active disulfide: C44S and C49S. Redox properties of the FAD and interactions with pyridine nucleotides.
Topics: Binding Sites; Coloring Agents; Cysteine; Dihydrolipoamide Dehydrogenase; Disulfides; Electron Transport; Escherichia coli; Flavin-Adenine Dinucleotide; Hydrogen-Ion Concentration; Kinetics; Mutagenesis, Site-Directed; NAD; NADP; Oxidation-Reduction; Phenazines; Serine; Viologens | 1995 |
Organization in the membrane of the N-terminal proton-translocating domain of the beta subunit of the pyridine nucleotide transhydrogenase of Escherichia coli.
Topics: Amino Acid Sequence; Binding Sites; Cell Membrane; Cysteine; Escherichia coli; Ion Transport; Molecular Sequence Data; Mutagenesis, Site-Directed; NADP; NADP Transhydrogenases; Protons; Sulfhydryl Reagents | 1995 |
Stimulatory factors for enzymatic biotin synthesis from dethiobiotin in cell-free extracts of Escherichia coli.
Topics: Bacillus; Biotin; Cell Extracts; Cysteine; Escherichia coli; Flavin-Adenine Dinucleotide; Immunosuppressive Agents; NAD; NADP; S-Adenosylmethionine | 1995 |
Cysteine 707 is involved in the dehydrogenase activity site of rat 10-formyltetrahydrofolate dehydrogenase.
Topics: Animals; Base Sequence; Binding Sites; Cysteine; Molecular Sequence Data; Mutagenesis, Site-Directed; NADP; Oxidoreductases Acting on CH-NH Group Donors; Protein Conformation; Rats; Spectrometry, Fluorescence | 1995 |
Mechanism of light modulation: identification of potential redox-sensitive cysteines distal to catalytic site in light-activated chloroplast enzymes.
Topics: Amino Acid Sequence; Animals; Binding Sites; Chloroplasts; Cysteine; Disulfides; Fabaceae; Fructose-Bisphosphatase; Glyceraldehyde-3-Phosphate Dehydrogenases; Light; Malate Dehydrogenase; Models, Molecular; Molecular Sequence Data; NADP; Phosphoric Monoester Hydrolases; Plants, Medicinal; Protein Structure, Tertiary; Sequence Homology, Amino Acid; Swine; Triticum | 1994 |
Selective cysteine-->serine replacements in p-hydroxybenzoate hydroxylase from Pseudomonas fluorescens allow the unambiguous assignment of Cys211 as the site of modification by spin-labeled p-chloromercuribenzoate.
Topics: 4-Hydroxybenzoate-3-Monooxygenase; Base Sequence; Catalysis; Chloromercuribenzoates; Cysteine; Electron Spin Resonance Spectroscopy; Kinetics; Molecular Sequence Data; Mutagenesis, Site-Directed; NADP; p-Chloromercuribenzoic Acid; Pseudomonas fluorescens; Serine; Spin Labels; Structure-Activity Relationship | 1994 |
Thioredoxin-dependent peroxide reductase from yeast.
Topics: Amino Acid Sequence; Antioxidants; Ascorbic Acid; Base Sequence; Cloning, Molecular; Cysteine; Dithiothreitol; Fungal Proteins; Genes, Fungal; Molecular Sequence Data; Molecular Weight; Mutagenesis, Site-Directed; NADP; Neoplasm Proteins; Oxidation-Reduction; Peroxidases; Peroxiredoxins; Protein Conformation; Proteins; Saccharomyces cerevisiae; Structure-Activity Relationship; Thioredoxin-Disulfide Reductase; Thioredoxins | 1994 |
Protein S-thiolation and dethiolation.
Topics: Animals; Carbonic Anhydrases; Cells, Cultured; Chromatography, High Pressure Liquid; Creatine Kinase; Cysteine; Cystine; Disulfides; Glutathione; Glutathione Disulfide; Indicators and Reagents; Methionine; Muscles; NADP; Phosphorylase b; Protein Biosynthesis; Proteins; Rabbits; Radioisotope Dilution Technique; Sulfur Radioisotopes | 1994 |
Site-directed mutagenesis of cysteine residues in biliverdin reductase. Roles in substrate and cofactor binding.
Topics: Amino Acid Sequence; Animals; Base Sequence; Biliverdine; Binding Sites; Blotting, Western; Cloning, Molecular; Cysteine; DNA Primers; Kidney; Kinetics; Molecular Sequence Data; Molecular Weight; Mutagenesis, Site-Directed; NAD; NADP; Oxidoreductases; Oxidoreductases Acting on CH-CH Group Donors; Rats; Recombinant Proteins | 1994 |
Identification and characterization of the second regulatory disulfide bridge of recombinant sorghum leaf NADP-malate dehydrogenase.
Topics: Amino Acid Sequence; Base Sequence; Chloroplasts; Computer Graphics; Cysteine; Disulfides; Enzyme Activation; Kinetics; Malate Dehydrogenase; Malate Dehydrogenase (NADP+); Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; NADP; Oligodeoxyribonucleotides; Poaceae; Protein Structure, Secondary; Recombinant Proteins | 1994 |
Crystal structure of Escherichia coli thioredoxin reductase refined at 2 A resolution. Implications for a large conformational change during catalysis.
Topics: Amino Acid Sequence; Binding Sites; Computer Graphics; Crystallography, X-Ray; Cysteine; Escherichia coli; Flavin-Adenine Dinucleotide; Models, Molecular; Models, Structural; Molecular Sequence Data; NADP; Oxidation-Reduction; Protein Conformation; Protein Structure, Secondary; Thioredoxin-Disulfide Reductase | 1994 |
The pH-dependent behavior of catalytic activities of Azospirillum brasilense glutamate synthase and iodoacetamide modification of the enzyme provide evidence for a catalytic Cys-His ion pair.
Topics: Amino Acid Sequence; Ammonia; Azospirillum brasilense; Catalysis; Cysteine; Glutamate Synthase; Glutamine; Histidine; Hydrogen-Ion Concentration; Iodoacetamide; Ketoglutaric Acids; Kinetics; Molecular Sequence Data; NADP; Sequence Analysis | 1994 |
Human placental aldose reductase: role of Cys-298 in substrate and inhibitor binding.
Topics: Aldehyde Reductase; Aldehydes; Circular Dichroism; Cysteine; Deuterium; Female; Humans; Imidazoles; Imidazolidines; Iodoacetates; Iodoacetic Acid; Kinetics; NADP; Naphthalenes; Placenta; Pregnancy; Quercetin; Spectrophotometry, Ultraviolet | 1994 |
Selective and irreversible inhibition of glutathione reductase in vitro by carbamate thioester conjugates of methyl isocyanate.
Topics: Amino Acid Sequence; Binding Sites; Carbamates; Cysteine; Glutathione; Glutathione Reductase; Humans; Isocyanates; Molecular Sequence Data; NADP; Saccharomyces cerevisiae | 1994 |
Singlet-oxygen generation at gas-liquid interfaces: a significant artifact in the measurement of singlet-oxygen yields from ozone-biomolecule reactions.
Topics: Albumins; Cysteine; Gases; Glutathione; Humans; Methionine; NAD; NADP; Oxygen; Ozone; Singlet Oxygen; Uric Acid | 1993 |
Collapse of parallel folding channels in dihydrofolate reductase from Escherichia coli by site-directed mutagenesis.
Topics: Circular Dichroism; Cysteine; Escherichia coli; Flow Cytometry; Folic Acid Antagonists; Kinetics; Magnetic Resonance Spectroscopy; Methotrexate; Mutagenesis, Site-Directed; NADP; Protein Conformation; Protein Folding; Tetrahydrofolate Dehydrogenase; Thermodynamics; Urea | 1993 |
Identification of the reactive cysteine residue in human placenta aldose reductase.
Topics: Adenosine Diphosphate Ribose; Aldehyde Reductase; Amino Acid Sequence; Binding Sites; Carbon Radioisotopes; Cysteine; Humans; Iodoacetates; Iodoacetic Acid; Kinetics; Molecular Sequence Data; NADP; Placenta; Trypsin | 1993 |
Mutagenesis of structural half-cystine residues in human thioredoxin and effects on the regulation of activity by selenodiglutathione.
Topics: Amino Acid Sequence; Base Sequence; Cysteine; Cystine; Glutathione; Humans; Kinetics; Molecular Sequence Data; NADP; Oligodeoxyribonucleotides; Organoselenium Compounds; Oxidation-Reduction; Protein Denaturation; Recombinant Proteins; Thioredoxins | 1993 |
A thioredoxin-independent fully active NADP-malate dehydrogenase obtained by site-directed mutagenesis.
Topics: Base Sequence; Cysteine; Malate Dehydrogenase; Molecular Sequence Data; Mutagenesis, Site-Directed; NADP; Oligodeoxyribonucleotides; Plant Proteins; Plants; Structure-Activity Relationship; Thioredoxins | 1993 |
The role of cysteine residues of spinach ferredoxin-NADP+ reductase As assessed by site-directed mutagenesis.
Topics: Amino Acid Sequence; Base Sequence; Binding Sites; Circular Dichroism; Computer Graphics; Cysteine; Ferredoxin-NADP Reductase; Kinetics; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; NADP; Oligodeoxyribonucleotides; Plants; Protein Conformation; Protein Structure, Secondary; Recombinant Proteins | 1993 |
Involvement of cysteine 289 in the catalytic activity of an NADP(+)-specific fatty aldehyde dehydrogenase from Vibrio harveyi.
Topics: Aldehyde Oxidoreductases; Amino Acid Sequence; Animals; Base Sequence; Binding Sites; Catalysis; Cloning, Molecular; Conserved Sequence; Cysteine; DNA, Bacterial; Escherichia coli; Genes, Bacterial; Kinetics; Luminescent Measurements; Molecular Sequence Data; Mutagenesis, Site-Directed; NADP; Rats; Recombinant Proteins; Sequence Homology, Amino Acid; Vibrio | 1995 |
Inactivation of an NADPH-dependent succinic semialdehyde reductase by o-phthalaldehyde.
Topics: Animals; Binding Sites; Brain; Cattle; Cross-Linking Reagents; Cysteine; Enzyme Inhibitors; Hydroxybutyrate Dehydrogenase; Indoles; Kinetics; Lysine; NADP; o-Phthalaldehyde | 1996 |
The function and properties of the iron-sulfur center in spinach ferredoxin: thioredoxin reductase: a new biological role for iron-sulfur clusters.
Topics: Chloroplasts; Circular Dichroism; Cysteine; Disulfides; Dithiothreitol; Electron Spin Resonance Spectroscopy; Electron Transport; Ethylmaleimide; Ferredoxins; Ferricyanides; Iron; Iron-Sulfur Proteins; NADP; Oxidoreductases; Spectrophotometry; Spectrum Analysis, Raman; Spinacia oleracea; Sulfur | 1996 |
Reductase domain cysteines 1048 and 1114 are critical for catalytic activity of human endothelial cell nitric oxide synthase as probed by site-directed mutagenesis.
Topics: Animals; Base Sequence; Catalysis; Cell Line; Cysteine; Cytochrome c Group; DNA, Complementary; Endothelium; Humans; Molecular Sequence Data; Mutagenesis, Site-Directed; NADP; Nitric Oxide Synthase; Oxidation-Reduction; Oxidoreductases | 1996 |
Nitric oxide inhibits aromatase activity: mechanisms of action.
Topics: Androstenedione; Aromatase Inhibitors; Carbon Monoxide; Cells, Cultured; Cysteine; Enzyme Inhibitors; Ethylmaleimide; Female; Gene Expression Regulation, Enzymologic; Granulosa Cells; Humans; Luteal Cells; Mercaptoethanol; Microsomes; NADP; Nitric Oxide; Penicillamine; Placenta; RNA, Messenger; S-Nitroso-N-Acetylpenicillamine; Sulfhydryl Reagents | 1996 |
Cleavage of DNA by the insulin-mimetic compound, NH4[VO(O2)2(phen)].
Topics: Ascorbic Acid; Cysteine; DNA; Electron Spin Resonance Spectroscopy; Electrophoresis, Agar Gel; Escherichia coli; Glutathione; Hydrogen-Ion Concentration; Hypoglycemic Agents; Kinetics; Magnetic Resonance Spectroscopy; NADP; Photolysis; Plasmids; Ultraviolet Rays; Vanadates | 1996 |
Comparative inhibition of yeast glutathione reductase by arsenicals and arsenothiols.
Topics: Arsenicals; Chelating Agents; Cysteine; Glutathione; Glutathione Disulfide; Glutathione Reductase; NADP; Oxidation-Reduction; Structure-Activity Relationship; Succimer; Sulfhydryl Compounds; Yeasts | 1997 |
Thiols and neuronal nitric oxide synthase: complex formation, competitive inhibition, and enzyme stabilization.
Topics: Animals; Arginine; Biopterins; Calmodulin; Cysteine; Dithiothreitol; Enzyme Inhibitors; Enzyme Stability; Flavin-Adenine Dinucleotide; Heme; Mercaptoethanol; NADP; Neurons; Nitric Oxide Synthase; Protein Binding; Rats; Spectrometry, Fluorescence; Spectrophotometry; Sulfhydryl Compounds; Temperature | 1997 |
Site-directed mutagenesis of the cysteine residues in the Pichia stipitis xylose reductase.
Topics: 4-Chloromercuribenzenesulfonate; Aldehyde Reductase; Binding Sites; Cloning, Molecular; Coenzymes; Cysteine; Enzyme Inhibitors; Mutagenesis, Site-Directed; NAD; NADP; Pichia; Plasmids; Polymerase Chain Reaction; Recombinant Proteins; Recombination, Genetic; Serine; Xylose | 1997 |
Studies comparing the kinetics of cysteine conjugation and protein binding of acetaminophen by hepatic microsomes from male mice.
Topics: Acetaminophen; Animals; Cysteine; Cytochrome P-450 CYP2E1; Ethanol; Male; Mice; Microsomes, Liver; NAD; NADP; Protein Binding | 1997 |
Aromatase inactivation by a suicide substrate, androst-5-ene-4,7,17-trione: the 5beta,6beta-epoxy-19-oxo derivative, as a possible reactive electrophile irreversibly binding to the active site.
Topics: Acetylcysteine; Androstanes; Androstenedione; Androstenes; Aromatase Inhibitors; Binding Sites; Binding, Competitive; Cysteine; Female; Humans; In Vitro Techniques; Kinetics; Microsomes; NADP; Placenta; Pregnancy | 1997 |
Properties of a cysteine-free proton-pumping nicotinamide nucleotide transhydrogenase.
Topics: Bacterial Proteins; Catalysis; Cysteine; Escherichia coli; Membrane Proteins; Mutagenesis, Site-Directed; NADP; NADP Transhydrogenases; Proteolipids; Protons; Recombinant Fusion Proteins; Structure-Activity Relationship | 1997 |
Evidence for two conformational states of thioredoxin reductase from Escherichia coli: use of intrinsic and extrinsic quenchers of flavin fluorescence as probes to observe domain rotation.
Topics: Adenine Nucleotides; Amino Acid Sequence; Binding Sites; Cysteine; Disulfides; Endopeptidases; Escherichia coli; Flavin-Adenine Dinucleotide; Fluorescent Dyes; Kinetics; Mutation; NADP; Peptide Fragments; Protein Conformation; Spectrometry, Fluorescence; Tetradecanoylphorbol Acetate; Thioredoxin-Disulfide Reductase | 1997 |
Effect of selective cysteine --> alanine replacements on the catalytic functions of lysine: N6-hydroxylase.
Topics: 2,6-Dichloroindophenol; Alanine; Amino Acid Sequence; Base Sequence; Cloning, Molecular; Cyanogen Bromide; Cysteine; Dithionitrobenzoic Acid; Flavoproteins; Iodoacetates; Iodoacetic Acid; Lysine; Mass Spectrometry; Mixed Function Oxygenases; Molecular Sequence Data; Mutagenesis, Site-Directed; NADP; Peptide Fragments; Protein Conformation; Recombinant Proteins; Sequence Analysis; Trypsin | 1997 |
Site-specific inactivation of aldose reductase by 4-hydroxynonenal.
Topics: Aldehyde Reductase; Aldehydes; Animals; Antioxidants; Captopril; Cattle; Cysteine; Dithiothreitol; Glutathione Disulfide; Lens, Crystalline; NADP | 1998 |
In vitro and in vivo regulation of assimilatory nitrite reductase from Candida utilis.
Topics: Ammonium Chloride; Candida; Chloromercuribenzoates; Cysteine; Enzyme Induction; Enzyme Repression; Flavin-Adenine Dinucleotide; Gene Expression Regulation, Enzymologic; Kinetics; NAD; NADP; Nitrite Reductase (NAD(P)H); Nitrite Reductases; p-Chloromercuribenzoic Acid | 1997 |
Formation and properties of mixed disulfides between thioredoxin reductase from Escherichia coli and thioredoxin: evidence that cysteine-138 functions to initiate dithiol-disulfide interchange and to accept the reducing equivalent from reduced flavin.
Topics: Cysteine; Disulfides; Dithionite; Dithionitrobenzoic Acid; Dithiothreitol; Escherichia coli; Flavin-Adenine Dinucleotide; Hydrogen-Ion Concentration; Mutagenesis, Site-Directed; NADP; Osmolar Concentration; Oxidation-Reduction; Protein Conformation; Protein Engineering; Spectrometry, Fluorescence; Structure-Activity Relationship; Sulfhydryl Compounds; Thioredoxin-Disulfide Reductase; Thioredoxins | 1998 |
Rapid reduction of Hg(II) by mercuric ion reductase does not require the conserved C-terminal cysteine pair using HgBr2 as the substrate.
Topics: Alanine; Bacillus; Binding Sites; Bromides; Catalysis; Conserved Sequence; Cysteine; Glutathione Reductase; Kinetics; Mercury Compounds; Models, Molecular; Mutagenesis, Site-Directed; NADP; Oxidation-Reduction; Oxidoreductases; Peptide Fragments; Substrate Specificity | 1998 |
The C331A mutant of neuronal nitric-oxide synthase is defective in arginine binding.
Topics: Animals; Arginine; Biopterins; Calmodulin; Carbon Monoxide; Catalytic Domain; Conserved Sequence; Cysteine; Electron Spin Resonance Spectroscopy; Escherichia coli; Heme; Mutation; NADP; Neurons; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Oxidation-Reduction; Rats; Recombinant Proteins; Spectrophotometry; Structure-Activity Relationship | 1998 |
Coenzyme A-disulfide reductase from Staphylococcus aureus: evidence for asymmetric behavior on interaction with pyridine nucleotides.
Topics: Catalysis; Coenzyme A; Cysteine; Dithionite; Ferricyanides; Isoenzymes; Mass Spectrometry; NADH, NADPH Oxidoreductases; NADP; Oxidation-Reduction; Recombinant Proteins; Serine; Spectrometry, Fluorescence; Spectrophotometry; Staphylococcus aureus | 1999 |
Tumor promoter benzoyl peroxide induces sulfhydryl oxidation in protein kinase C: its reversibility is related to the cellular resistance to peroxide-induced cytotoxicity.
Topics: Animals; Benzoyl Peroxide; Calcium; Cell Compartmentation; Cell Line; Cysteine; Glucose; Liposomes; Mice; NADP; Oxidants; Oxidation-Reduction; Phorbol 12,13-Dibutyrate; Phosphoprotein Phosphatases; Protein Kinase C; Protein Phosphatase 2; Rats; Sodium Dodecyl Sulfate; Sulfhydryl Compounds; Sulfhydryl Reagents | 1999 |
Equilibrium analyses of the active-site asymmetry in enterococcal NADH oxidase: role of the cysteine-sulfenic acid redox center.
Topics: Bacterial Proteins; Binding Sites; Coenzymes; Cysteine; Dithionite; Electron Transport; Enzyme Stability; Hydrogen-Ion Concentration; Multienzyme Complexes; Mutagenesis, Site-Directed; NAD; NADH, NADPH Oxidoreductases; NADP; Oxidation-Reduction; Recombinant Proteins; Serine; Spectrometry, Fluorescence; Sulfenic Acids | 1999 |
Thioredoxin reductase from Plasmodium falciparum: evidence for interaction between the C-terminal cysteine residues and the active site disulfide-dithiol.
Topics: Alanine; Animals; Binding Sites; Cysteine; Disulfides; Dithionite; Dithionitrobenzoic Acid; Kinetics; Mutagenesis, Site-Directed; NADP; Oxidation-Reduction; Peptide Fragments; Plasmodium falciparum; Thioredoxin-Disulfide Reductase; Titrimetry; Toluene | 1999 |
The cysteine-proximal aspartates in the Fx-binding niche of photosystem I. Effect of alanine and lysine replacements on photoautotrophic growth, electron transfer rates, single-turnover flash efficiency, and EPR spectral properties.
Topics: Alanine; Amino Acid Substitution; Aspartic Acid; Bacterial Proteins; Binding Sites; Cyanobacteria; Cysteine; Electron Spin Resonance Spectroscopy; Electron Transport; Kinetics; Lysine; Membrane Proteins; Mutagenesis, Site-Directed; NADP; Photosynthetic Reaction Center Complex Proteins; Photosystem I Protein Complex; Structure-Activity Relationship | 1999 |
Kinetic mechanism of cytochrome P450 reductase from the house fly (Musca domestica).
Topics: Animals; Cysteine; Cytochrome c Group; Electrons; Houseflies; Kinetics; Mutagenesis, Site-Directed; NADP; NADPH-Ferrihemoprotein Reductase; Recombinant Fusion Proteins; Tyrosine | 1999 |
Studies of the time-dependent inactivation of aromatase by 4beta,5beta-epoxy-6-one and 5beta,6beta-epoxy-4-one steroids under various conditions.
Topics: Androstenedione; Aromatase Inhibitors; Cysteine; Enzyme Inhibitors; Female; Humans; In Vitro Techniques; Kinetics; Microsomes; NADP; Placenta; Pregnancy; Stereoisomerism; Steroids; Time Factors | 1999 |
Lysine 219 participates in NADPH specificity in a flavin-containing monooxygenase from Saccharomyces cerevisiae.
Topics: Amino Acid Sequence; Amino Acid Substitution; Binding Sites; Cysteine; Escherichia coli; Flavin-Adenine Dinucleotide; Kinetics; Lysine; Molecular Sequence Data; Mutagenesis, Site-Directed; NAD; NADP; Oxidation-Reduction; Oxygenases; Phosphates; Recombinant Proteins; Saccharomyces cerevisiae; Sequence Alignment; Substrate Specificity | 1999 |
Application of metabolic flux analysis for the identification of metabolic bottlenecks in the biosynthesis of penicillin-G.
Topics: Acetic Acid; Biological Transport, Active; Biotechnology; Cell Compartmentation; Cell Membrane; Culture Media; Cysteine; Cytosol; Ethanol; Glucose; Kinetics; Models, Biological; NADP; Penicillin G; Penicillium chrysogenum | 2000 |
Structure and mechanism of mammalian thioredoxin reductase: the active site is a redox-active selenolthiol/selenenylsulfide formed from the conserved cysteine-selenocysteine sequence.
Topics: Animals; Binding Sites; Cattle; Cysteine; Glutathione Reductase; Mass Spectrometry; Models, Molecular; NADP; Oxidation-Reduction; Selenocysteine; Thioredoxin-Disulfide Reductase | 2000 |
Structural and biochemical investigations of the catalytic mechanism of an NADP-dependent aldehyde dehydrogenase from Streptococcus mutans.
Topics: Acylation; Aldehyde Dehydrogenase; Amino Acid Substitution; Apoenzymes; Binding Sites; Catalysis; Crystallography, X-Ray; Cysteine; Glutamic Acid; Holoenzymes; Hydrogen Bonding; Hydrogen-Ion Concentration; Kinetics; Models, Molecular; Molecular Sequence Data; Mutation; NADP; Pliability; Protein Conformation; Streptococcus mutans; Sulfates | 2000 |
Serine 121 is an essential amino acid for biotin sulfoxide reductase functionality.
Topics: Alanine; Amino Acid Sequence; Amino Acids; Binding Sites; Biotin; Catalysis; Chromatography, High Pressure Liquid; Coenzymes; Conserved Sequence; Cysteine; Electrophoresis, Polyacrylamide Gel; Escherichia coli; Factor Xa; Glutathione Transferase; Guanine Nucleotides; Iron-Sulfur Proteins; Ligands; Mass Spectrometry; Metalloproteins; Molecular Sequence Data; Molybdenum Cofactors; Mutagenesis, Site-Directed; NADP; Oxidative Stress; Oxidoreductases; Oxygen; Paraquat; Pteridines; Pterins; Recombinant Fusion Proteins; Rhodobacter sphaeroides; Sequence Homology, Amino Acid; Serine; Spectrometry, Fluorescence; Threonine; Time Factors | 2000 |
A histidine residue in the catalytic mechanism distinguishes Vibrio harveyi aldehyde dehydrogenase from other members of the aldehyde dehydrogenase superfamily.
Topics: Acyl Coenzyme A; Acylation; Acyltransferases; Aldehyde Dehydrogenase; Animals; Binding Sites; Catalytic Domain; Cysteine; Enzyme Activation; Esterases; Ethylmaleimide; Histidine; Kinetics; Multigene Family; Mutagenesis, Site-Directed; NADP; Niacinamide; Rats; Sequence Homology, Amino Acid; Thiolester Hydrolases; Vibrio | 2000 |
Activation of class III ribonucleotide reductase by thioredoxin.
Topics: Animals; Arabidopsis; Chlamydomonas reinhardtii; Cysteine; Disulfides; Dithiothreitol; Dose-Response Relationship, Drug; Enzyme Activation; Escherichia coli; Free Radicals; NADP; Protein Structure, Tertiary; Ribonucleotide Reductases; S-Adenosylmethionine; Spectrophotometry; Thioredoxins; Time Factors; Ultraviolet Rays | 2001 |
Identification of a region involved in the communication between the NADP(H) binding domain and the membrane domain in proton pumping E. coli transhydrogenase.
Topics: Amino Acid Sequence; Anilino Naphthalenesulfonates; Cell Membrane; Cysteine; Electrophoresis, Polyacrylamide Gel; Escherichia coli; Hydrogen-Ion Concentration; Kinetics; Magnesium Chloride; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; NADP; NADP Transhydrogenases; Plasmids; Protein Binding; Protein Conformation; Protein Structure, Tertiary; Proteolipids; Protons; Spectrometry, Fluorescence; Time Factors | 2001 |
Interaction of camel lens zeta-crystallin with quinones: portrait of a substrate by fluorescence spectroscopy.
Topics: 2,6-Dichloroindophenol; Animals; Camelus; Catalysis; Crystallins; Cysteine; Dose-Response Relationship, Drug; Kinetics; Lens, Crystalline; Ligands; NADP; Naphthoquinones; Protein Binding; Spectrometry, Fluorescence | 2001 |
Mutation in the glucose-6-phosphate dehydrogenase gene leads to inactivation of Ku DNA end binding during oxidative stress.
Topics: Animals; Antigens, Nuclear; Blotting, Western; Cell Nucleus; CHO Cells; Chromatography, High Pressure Liquid; Cricetinae; Cysteine; Disulfides; Dithiothreitol; DNA; DNA Damage; DNA Helicases; DNA Repair; DNA-Binding Proteins; Ethanol; Glucosephosphate Dehydrogenase; Ku Autoantigen; Models, Chemical; Mutation; NAD; NADP; Nuclear Proteins; Oxidative Stress; Protein Binding; Reducing Agents; Sulfhydryl Compounds; Time Factors; Transfection | 2002 |
Degradation of L-glutamate dehydrogenase from Escherichia coli: allosteric regulation of enzyme stability.
Topics: Adenosine Triphosphatases; Allosteric Regulation; Ammonia; Aspartate Kinase; ATP-Dependent Proteases; Carboxylic Acids; Chloramphenicol; Cysteine; Endopeptidase Clp; Enzyme Stability; Escherichia coli; Escherichia coli Proteins; Glucose; Glutamate Dehydrogenase; Heat-Shock Proteins; Models, Molecular; NADP; NF-kappa B; Nucleotides; Phenylmethylsulfonyl Fluoride; Potassium Cyanide; Protease La; Protein Conformation; Protein Processing, Post-Translational; Serine Endopeptidases; Transcription Factor RelA | 2002 |
Modulation of the reactivity of the essential cysteine residue of betaine aldehyde dehydrogenase from Pseudomonas aeruginosa.
Topics: Aldehyde Oxidoreductases; Anti-Bacterial Agents; Betaine-Aldehyde Dehydrogenase; Cysteine; Hydrogen-Ion Concentration; Ions; Kinetics; Models, Chemical; NADP; Protein Binding; Protein Conformation; Pseudomonas aeruginosa; Sulfinic Acids; Sulfonic Acids; Time Factors | 2002 |
Inactivation of human peroxiredoxin I during catalysis as the result of the oxidation of the catalytic site cysteine to cysteine-sulfinic acid.
Topics: Amino Acid Sequence; Antioxidants; Catalysis; Catalytic Domain; Cysteine; HeLa Cells; Humans; Hydrogen Peroxide; Hydrogen-Ion Concentration; Molecular Sequence Data; Mutation; NADP; Oxidants; Oxidation-Reduction; Peptides; Peroxidases; Peroxiredoxins; Recombinant Proteins; Spectrometry, Mass, Electrospray Ionization; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Thioredoxin-Disulfide Reductase; Thioredoxins | 2002 |
Redox-sensitive loops D and E regulate NADP(H) binding in domain III and domain I-domain III interactions in proton-translocating Escherichia coli transhydrogenase.
Topics: Catalysis; Cysteine; Escherichia coli; Mutagenesis, Site-Directed; Mutation; NADP; NADP Transhydrogenases; Protein Conformation; Protein Structure, Tertiary; Protons; Spectrometry, Fluorescence | 2002 |
A structural basis for the mechanism of aspartate-beta-semialdehyde dehydrogenase from Vibrio cholerae.
Topics: Apoenzymes; Aspartate-Semialdehyde Dehydrogenase; Binding Sites; Cysteine; Enzyme Inhibitors; Escherichia coli; Methylation; Models, Molecular; NADP; Protein Conformation; Vibrio cholerae | 2003 |
Structural and thermodynamic studies on a salt-bridge triad in the NADP-binding domain of glutamate dehydrogenase from Thermotoga maritima: cooperativity and electrostatic contribution to stability.
Topics: Alanine; Arginine; Binding Sites; Crystallography, X-Ray; Cysteine; Enzyme Stability; Glutamate Dehydrogenase; Glutamic Acid; Guanidine; Lysine; Mutagenesis, Site-Directed; NADP; Protein Denaturation; Protein Folding; Protein Structure, Tertiary; Recombinant Proteins; Salts; Serine; Static Electricity; Structure-Activity Relationship; Thermodynamics; Thermotoga maritima; Urea | 2002 |
The CXC motif: a functional mimic of protein disulfide isomerase.
Topics: Amino Acid Motifs; Binding Sites; Cysteine; Disulfides; Escherichia coli; Genetic Vectors; Kinetics; Molecular Mimicry; Mutation; NADP; Oxidation-Reduction; Protein Conformation; Protein Disulfide-Isomerases; Protein Folding; Spectrometry, Fluorescence; Substrate Specificity; Sulfhydryl Compounds; Thioredoxin-Disulfide Reductase; Thioredoxins | 2003 |
Roles of individual amino acids in helix 14 of the membrane domain of proton-translocating transhydrogenase from Escherichia coli as deduced from cysteine mutagenesis.
Topics: Alkaline Phosphatase; Amino Acids; Binding Sites; Cysteine; Escherichia coli; Ethylmaleimide; Glycine; Models, Chemical; Mutagenesis, Site-Directed; Mutation; NAD; NADP; NADP Transhydrogenases; Plasmids; Protein Structure, Tertiary; Protons; Serine | 2003 |
Redox potential of human thioredoxin 1 and identification of a second dithiol/disulfide motif.
Topics: Amino Acid Motifs; Amino Acid Sequence; Binding Sites; Blotting, Western; Bridged Bicyclo Compounds; Cell Line; Chromatography, High Pressure Liquid; Cysteine; Disulfides; Glutathione; Humans; Mass Spectrometry; Membrane Proteins; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; NADP; Oxidation-Reduction; Oxidative Stress; Oxygen; Protein Structure, Tertiary; Recombinant Proteins; Signal Transduction; Spectrometry, Fluorescence; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Thioredoxin-Disulfide Reductase; Thioredoxins; Time Factors; Trypsin | 2003 |
The mechanism of high Mr thioredoxin reductase from Drosophila melanogaster.
Topics: Animals; Catalysis; Chelating Agents; Cysteine; Dimerization; Disulfides; Drosophila melanogaster; Edetic Acid; Ferricyanides; Hydrogen-Ion Concentration; Kinetics; Light; Models, Biological; Models, Chemical; Mutation; NADP; Oxidation-Reduction; Oxygen; Plasmodium falciparum; Protein Structure, Tertiary; Recombinant Proteins; Sulfhydryl Compounds; Thioredoxin Reductase 1; Thioredoxin-Disulfide Reductase; Thioredoxins | 2003 |
Electron transfer in flavocytochrome P450 BM3: kinetics of flavin reduction and oxidation, the role of cysteine 999, and relationships with mammalian cytochrome P450 reductase.
Topics: Amino Acid Sequence; Amino Acid Substitution; Animals; Bacterial Proteins; Binding Sites; Cysteine; Cytochrome P-450 Enzyme System; Escherichia coli Proteins; Flavin-Adenine Dinucleotide; Flavins; Humans; Kinetics; Mixed Function Oxygenases; Molecular Sequence Data; Mutagenesis, Site-Directed; NADP; NADPH-Ferrihemoprotein Reductase; Protein Structure, Tertiary; Recombinant Proteins; Sequence Homology, Amino Acid; Spectrophotometry | 2003 |
Functional split and crosslinking of the membrane domain of the beta subunit of proton-translocating transhydrogenase from Escherichia coli.
Topics: Catalysis; Codon; Cross-Linking Reagents; Cysteine; Electrophoresis, Polyacrylamide Gel; Escherichia coli; Factor Xa; Kinetics; Models, Biological; Mutagenesis; Mutagenesis, Site-Directed; Mutation; NAD; NADP; NADP Transhydrogenases; Peptides; Plasmids; Protein Conformation; Protein Folding; Protein Structure, Tertiary; Proteolipids; Protons; Time Factors; Trypsin | 2003 |
Iron-sulfur cluster N2 of the Escherichia coli NADH:ubiquinone oxidoreductase (complex I) is located on subunit NuoB.
Topics: Amino Acid Motifs; Amino Acid Sequence; Blotting, Western; Cell Division; Cysteine; Electron Spin Resonance Spectroscopy; Electron Transport Complex I; Escherichia coli; Escherichia coli Proteins; Ferredoxins; Gene Deletion; Genetic Vectors; Iron-Sulfur Proteins; Ligands; Magnetics; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; NADH, NADPH Oxidoreductases; NADP; Oxidation-Reduction; Peptides; Protons; Sequence Homology, Amino Acid | 2003 |
[STUDY OF THE PURIFICATION AND PROPERTIES OF 6-PHOSPHOGLUCONATE DEHYDROGENASE (6 PGD) EXTRACTED FROM BACILLUS SUBTILIS].
Topics: Alanine; Bacillus subtilis; Chromatography; Cysteine; Enzyme Inhibitors; Gluconates; Glycine; Glycosides; Ion Exchange Resins; NADP; Oxidoreductases; Peptides; Phosphogluconate Dehydrogenase; Prostaglandins D; Research; Sulfhydryl Compounds; Valine | 1963 |
NITRO-REDUCTASE FROM A NOCARDIA SP.
Topics: Aniline Compounds; Chromatography; Cysteine; Electrophoresis; NAD; NADP; Nitrobenzenes; Nocardia; Oxidoreductases; Research; Spectrophotometry; Sulfhydryl Compounds | 1964 |
STUDIES ON THE PYRIDINE NUCLEOTIDE SPECIFICITY OF NITRATE REDUCTASE IN HIGHER PLANTS AND ITS RELATIONSHIP TO SULFHYDRYL LEVEL.
Topics: Chemistry Techniques, Analytical; Cysteine; Edible Grain; Embryophyta; Glycine max; Hydrogen-Ion Concentration; Kinetics; NAD; NADP; Nitrate Reductase; Nitrate Reductases; Nucleotides; Oxidoreductases; Pyridines; Research; Sulfhydryl Compounds; Vegetables; Zea mays | 1964 |
A RAPID ASSAY FOR SULPHITE REDUCTASE.
Topics: Biological Assay; Colorimetry; Culture Media; Cysteine; Escherichia coli; Ethylmaleimide; Glutathione; Metabolism; Methionine; NADP; Oxidoreductases; Oxidoreductases Acting on Sulfur Group Donors; Pyrroles; Research; Sulfides; Sulfites; Sulfonic Acids; Thiosulfates | 1964 |
THE EFFECT OF VARIOUS SULFITES AND GLYCEROL ON THE HEAT INACTIVATION OF 3-ALPHA-HYDROXYSTEROID DEHYDROGENASE OF RAT LIVER.
Topics: 3-alpha-Hydroxysteroid Dehydrogenase (B-Specific); Ascorbic Acid; Cysteine; Glycerol; Heparin; Hot Temperature; Hydroxysteroid Dehydrogenases; Liver; Metabolism; NAD; NADP; Pharmacology; Rats; Research; Sulfhydryl Compounds; Sulfites | 1964 |
ON THE GLUCOSE-6-PHOSPHATE DEHYDROGENASE OF CERATOCYSTIS ULMI.
Topics: Benzoates; Biochemical Phenomena; Biochemistry; Chloromercuribenzoates; Cysteine; Enzyme Inhibitors; Fungi; Glucosephosphate Dehydrogenase; Iodoacetates; NADP; Research; Sulfhydryl Compounds | 1964 |
CYSTEINE BIOSYNTHESIS IN NEUROSPORA CRASSA. I. THE METABOLISM OF SULFITE, SULFIDE, AND CYSTEINESULFINIC ACID.
Topics: Amino Acids; Cysteine; Flavin-Adenine Dinucleotide; Metabolism; Molecular Biology; Mutation; NADP; Neurospora; Neurospora crassa; Research; Sulfides; Sulfinic Acids; Sulfites | 1965 |
ENZYMIC PROPERTIES OF MALATE DEHYDROGENASE OF BACILLUS SUBTILIS.
Topics: Adenine Nucleotides; Bacillus subtilis; Benzoates; Chemical Phenomena; Chemistry; Chloromercuribenzoates; Cysteine; Keto Acids; Malate Dehydrogenase; Malates; Mercaptoethanol; Metals; NAD; NADP; Nucleotides; Oxaloacetates; Research; Sulfhydryl Compounds | 1965 |
THE ENZYMATIC OXIDATION OF CYSTEINE TO CYSTEINESULFINATE IN RAT LIVER.
Topics: Chromatography; Cysteine; Electrophoresis; Hydroxylamines; Liver; Liver Extracts; Metabolism; NADP; Oxidation-Reduction; Pharmacology; Rats; Research; Sulfinic Acids | 1965 |
THE REDUCTION OF INORGANIC SULPHATE TO INORGANIC SULPHITE IN THE SMALL INTESTINE OF THE RAT.
Topics: Chromatography; Cysteine; Glutathione; Glutathione Disulfide; Intestinal Mucosa; Intestine, Small; Metabolism; NADP; Nucleotidyltransferases; Phosphotransferases; Rats; Research; Sulfates; Sulfites | 1965 |
A COLORIMETRIC MICRO-METHOD FOR THE DETERMINATION OF GLUTATHIONE.
Topics: Adrenal Glands; Benzoates; Biochemical Phenomena; Biochemistry; Blood; Colorimetry; Cysteine; Dimercaprol; Ergothioneine; Erythrocytes; Glutathione; Glutathione Reductase; Indicators and Reagents; Liver; Mercaptoethylamines; Methionine; Microchemistry; NADP; Nerve Tissue; Nitrobenzenes; Pituitary Gland; Research; Retina; Sulfhydryl Compounds; Sulfides | 1965 |
Thiamine biosynthesis in Escherichia coli: in vitro reconstitution of the thiazole synthase activity.
Topics: Adenosine; Bacterial Proteins; Carbon-Sulfur Lyases; Carrier Proteins; Cell-Free System; Chromatography, High Pressure Liquid; Culture Media; Cysteine; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Escherichia coli; Escherichia coli Proteins; Ligases; Models, Chemical; NADP; Nucleotidyltransferases; Plasmids; S-Adenosylmethionine; Sulfurtransferases; Thiamine; Thiazoles; Time Factors; Tyrosine | 2004 |
An appraisal of multiple NADPH binding-site models proposed for cytochrome P450 reductase, NO synthase, and related diflavin reductase systems.
Topics: Alanine; Bacillus megaterium; Binding Sites; Catalysis; Cysteine; Flavin Mononucleotide; Flavin-Adenine Dinucleotide; Kinetics; Models, Chemical; Mutagenesis, Site-Directed; NADP; NADPH-Ferrihemoprotein Reductase; Nitric Oxide Synthase; Oxidation-Reduction; Spectrophotometry; Substrate Specificity | 2004 |
3alpha/beta,20beta-hydroxysteroid dehydrogenase (porcine testicular carbonyl reductase) also has a cysteine residue that is involved in binding of cofactor NADPH.
Topics: 20-Hydroxysteroid Dehydrogenases; Animals; Binding Sites; Cysteine; Dithionitrobenzoic Acid; Hydroxymercuribenzoates; Kinetics; Models, Molecular; NADP; Point Mutation; Protein Binding; Swine | 2004 |
Oxidation of thioredoxin reductase in HeLa cells stimulated with tumor necrosis factor-alpha.
Topics: Animals; Apoptosis; Cysteine; Cytoplasm; Disulfides; DNA Fragmentation; Genes, Dominant; HeLa Cells; Humans; Hydrogen Peroxide; Mitochondria, Liver; Mutation; NADP; Oxidation-Reduction; Rats; Recombinant Proteins; Selenocysteine; Thioredoxin Reductase 1; Thioredoxin Reductase 2; Thioredoxin-Disulfide Reductase; Tumor Necrosis Factor-alpha | 2004 |
Redox modulation of tau and microtubule-associated protein-2 by the glutathione/glutaredoxin reductase system.
Topics: Animals; Brain; Chromatography, High Pressure Liquid; Cysteine; Disulfides; Dose-Response Relationship, Drug; Escherichia coli; Fluoresceins; Glutaredoxins; Glutathione; Glutathione Reductase; Humans; Hydrogen Peroxide; Microtubule-Associated Proteins; Microtubules; Models, Chemical; NADP; Oxidants; Oxidation-Reduction; Oxidoreductases; Oxygen; Peroxynitrous Acid; Sulfhydryl Compounds; Swine; tau Proteins; Time Factors | 2004 |
Complete reversal of coenzyme specificity of xylitol dehydrogenase and increase of thermostability by the introduction of structural zinc.
Topics: Amino Acid Sequence; Blotting, Western; Catalysis; Cloning, Molecular; Cysteine; D-Xylulose Reductase; Electrophoresis, Polyacrylamide Gel; Escherichia coli; Ethanol; Fermentation; Histidine; Hot Temperature; Immunoblotting; Kinetics; Ligands; Models, Biological; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; NAD; NADP; Pichia; Protein Structure, Tertiary; Recombinant Proteins; Saccharomyces cerevisiae; Sequence Homology, Amino Acid; Spectrophotometry; Substrate Specificity; Sugar Alcohol Dehydrogenases; Temperature; Time Factors; Xylose; Zinc | 2005 |
Regulation of mitochondrial NADP+-dependent isocitrate dehydrogenase activity by glutathionylation.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Brain; Cell Line; Cysteine; Diamide; Disulfides; DNA Fragmentation; Dopamine Agents; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Genetic Vectors; Glutathione; Humans; Hydrogen Peroxide; Immunoblotting; Immunoprecipitation; Isocitrate Dehydrogenase; Mass Spectrometry; Mice; Mice, Inbred ICR; Mitochondria; Mutagenesis, Site-Directed; NADP; Oxidants; Oxidation-Reduction; Oxidative Stress; Oxygen; Rabbits; Sulfhydryl Compounds; Time Factors | 2005 |
Role of methionine-13 in the catalytic mechanism of 6-phosphogluconate dehydrogenase from sheep liver.
Topics: Amino Acid Sequence; Animals; Catalysis; Circular Dichroism; Cysteine; Deuterium Exchange Measurement; Glutamine; Kinetics; Liver; Methionine; Molecular Sequence Data; Mutagenesis, Site-Directed; NADP; Phenylalanine; Phosphogluconate Dehydrogenase; Sheep | 2005 |
Mechanistic studies on a novel, highly potent gold-phosphole inhibitor of human glutathione reductase.
Topics: Binding Sites; Borohydrides; Cell Division; Cysteine; Enzyme Inhibitors; Glioblastoma; Glutathione; Glutathione Reductase; Humans; Kinetics; Mass Spectrometry; Models, Molecular; NADP; Organometallic Compounds; Organophosphorus Compounds; Oxidation-Reduction; Recombinant Proteins; Tumor Cells, Cultured | 2005 |
Identification of amino acids required for the functional up-regulation of human dihydrofolate reductase protein in response to antifolate Treatment.
Topics: Amino Acids; Animals; Binding Sites; Blotting, Western; Catalysis; Cell Survival; CHO Cells; Cloning, Molecular; Cricetinae; Cysteine; DNA Primers; Folic Acid Antagonists; Gene Expression Regulation, Enzymologic; Glutamic Acid; Glutathione Transferase; Green Fluorescent Proteins; Humans; Inhibitory Concentration 50; Kinetics; Leucine; Methotrexate; Microscopy, Fluorescence; Models, Biological; Mutagenesis, Site-Directed; Mutation; NADP; Protein Biosynthesis; Recombinant Fusion Proteins; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Serine; Spectrophotometry; Tetrahydrofolate Dehydrogenase; Time Factors; Transcription, Genetic; Transfection; Up-Regulation | 2005 |
Thioredoxin reductase is irreversibly modified by curcumin: a novel molecular mechanism for its anticancer activity.
Topics: Animals; Anions; Antineoplastic Agents; Binding Sites; Cell Nucleus; Curcuma; Curcumin; Cysteine; Cytosol; Dose-Response Relationship, Drug; HeLa Cells; Humans; Inhibitory Concentration 50; Mass Spectrometry; Mitochondria; Models, Biological; Models, Chemical; NADP; NADPH Oxidases; Oxidants; Oxidation-Reduction; Peptides; Plant Extracts; Protein Binding; Rats; Selenocysteine; Superoxides; Temperature; Thioredoxin-Disulfide Reductase; Time Factors | 2005 |
Structure of the tetrameric form of human L-Xylulose reductase: probing the inhibitor-binding site with molecular modeling and site-directed mutagenesis.
Topics: Amino Acid Motifs; Amino Acid Sequence; Animals; Arginine; Binding Sites; Catalysis; Computational Biology; Cysteine; Dimerization; Enzyme Inhibitors; Humans; Hydrogen Bonding; Lung; Mice; Models, Chemical; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; NADP; Oxidoreductases; Protein Binding; Protein Conformation; Protein Folding; Protein Structure, Quaternary; Proteomics; Rats; Stereoisomerism; Sugar Alcohol Dehydrogenases | 2005 |
Thioredoxin reductase system mediates iron binding in IscA and iron delivery for the iron-sulfur cluster assembly in IscU.
Topics: Carrier Proteins; Catalysis; Citric Acid; Cysteine; Dose-Response Relationship, Drug; Escherichia coli; Escherichia coli Proteins; Iron; Iron-Sulfur Proteins; NADP; Protein Binding; Recombinant Proteins; Temperature; Thioredoxin-Disulfide Reductase | 2005 |
2-Acetylamino-3-[4-(2-acetylamino-2-carboxyethylsulfanylcarbonylamino)- phenylcarbamoylsulfanyl]propionic acid and its derivatives as a novel class of glutathione reductase inhibitors.
Topics: Carmustine; Cysteine; Glutathione Reductase; Kinetics; NADP; Solubility; Structure-Activity Relationship; Thiocarbamates | 2005 |
Post-translational regulation of mercaptopyruvate sulfurtransferase via a low redox potential cysteine-sulfenate in the maintenance of redox homeostasis.
Topics: Animals; Catalysis; Catalytic Domain; Cysteine; Dithiothreitol; DNA Primers; DNA, Complementary; Dose-Response Relationship, Drug; Glutathione; Homeostasis; Hydrogen Peroxide; Iodoacetates; Kinetics; Models, Chemical; Mutagenesis; NADP; Oxidants; Oxidation-Reduction; Oxidative Stress; Oxygen; Peroxidase; Protein Processing, Post-Translational; Rats; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Sulfenic Acids; Sulfur; Sulfurtransferases; Tetrathionic Acid; Thioredoxin-Disulfide Reductase; Thioredoxins; Thiosulfate Sulfurtransferase; Time Factors | 2005 |
Conformation coupled enzyme catalysis: single-molecule and transient kinetics investigation of dihydrofolate reductase.
Topics: Algorithms; Biotinylation; Catalysis; Cysteine; Escherichia coli; Fluorescence Resonance Energy Transfer; Fluorescent Dyes; Folic Acid; Hydrogen-Ion Concentration; Kinetics; Least-Squares Analysis; Models, Chemical; Mutagenesis, Site-Directed; Mutation; NADP; Protein Conformation; Recombinant Proteins; Spectrometry, Fluorescence; Statistical Distributions; Tetrahydrofolate Dehydrogenase | 2005 |
Mechanistic implications of the structure of the mixed-disulfide intermediate of the disulfide oxidoreductase, 2-ketopropyl-coenzyme M oxidoreductase/carboxylase.
Topics: Acetoacetates; Binding Sites; Carbon Dioxide; Carboxy-Lyases; Crystallography, X-Ray; Cysteine; Disulfides; Dithiothreitol; Enzyme Stability; Hydrophobic and Hydrophilic Interactions; Ketone Oxidoreductases; Models, Chemical; NADP; Oxidoreductases; Substrate Specificity | 2006 |
Disulfiram irreversibly aggregates betaine aldehyde dehydrogenase--a potential target for antimicrobial agents against Pseudomonas aeruginosa.
Topics: Alanine; Anti-Infective Agents; Betaine-Aldehyde Dehydrogenase; Binding Sites; Catalysis; Chromatography; Cysteine; Disulfiram; Dithionitrobenzoic Acid; Enzyme Inhibitors; Glutathione; Kinetics; Methyl Methanesulfonate; Models, Chemical; Mutagenesis, Site-Directed; Mutation; NADP; Protein Conformation; Protein Structure, Quaternary; Proteins; Pseudomonas aeruginosa; Sulfhydryl Compounds; Temperature; Time Factors | 2006 |
Mitochondrial NADP+-dependent isocitrate dehydrogenase protects cadmium-induced apoptosis.
Topics: Animals; Apoptosis; Cadmium; Cells, Cultured; Cysteine; Enzyme Activation; Glutaredoxins; Humans; Isocitrate Dehydrogenase; Mice; Mitochondria; NADP; Oxidation-Reduction; Oxidoreductases; Swine; Transfection | 2006 |
Cell signaling. H2O2, a necessary evil for cell signaling.
Topics: Cell Membrane; Cysteine; Cytosol; Humans; Hydrogen Peroxide; NADP; Organelles; Oxidation-Reduction; Peroxidases; Peroxiredoxins; Phosphorylation; Protein Tyrosine Phosphatases; Protein-Tyrosine Kinases; Proteins; Reactive Oxygen Species; Receptors, Cell Surface; Signal Transduction; Tyrosine | 2006 |
Functional and structural characterization of a thiol peroxidase from Mycobacterium tuberculosis.
Topics: Amino Acid Sequence; Binding Sites; Crystallography, X-Ray; Cysteine; Dimerization; Molecular Sequence Data; Molecular Weight; Mutant Proteins; Mutation; Mycobacterium tuberculosis; NADP; Oxidation-Reduction; Peroxidases; Protein Structure, Quaternary; Protein Structure, Secondary; Serine; Solutions | 2006 |
Thioredoxin-h1 reduces and reactivates the oxidized cytosolic malate dehydrogenase dimer in higher plants.
Topics: Arabidopsis; Chromatography, Affinity; Cysteine; Cytosol; Dimerization; Disulfides; Dithiothreitol; Escherichia coli; Malate Dehydrogenase; Mutation; NADP; Oxidation-Reduction; Peptide Mapping; Recombinant Proteins; Thioredoxins | 2006 |
Lipid lowering effect of S-methyl cysteine sulfoxide from Allium cepa Linn in high cholesterol diet fed rats.
Topics: Animals; Bile Acids and Salts; Cholesterol; Cholesterol, Dietary; Commiphora; Cysteine; Fatty Acids, Nonesterified; Feces; Glucosephosphate Dehydrogenase; Hyperlipidemias; Hypolipidemic Agents; Kidney; Lipoprotein Lipase; Liver; Male; Myocardium; NADP; Onions; Phospholipids; Plant Extracts; Plant Gums; Rats; Rats, Sprague-Dawley; Sterols; Triglycerides | 2007 |
Metabolism of furans in vitro: ipomeanine and 4-ipomeanol.
Topics: Acetylation; Animals; Cysteine; Furans; Glutathione; Glycine; Methylation; Microsomes; Molecular Structure; NADP; Oxidation-Reduction; Rats; Rats, Inbred F344; Terpenes | 2006 |
A generally applicable method for assessing the electrophilicity and reactivity of diverse nitrile-containing compounds.
Topics: Cathepsin K; Cathepsins; Computational Biology; Cysteine; Cysteine Proteinase Inhibitors; Electrochemistry; Humans; In Vitro Techniques; Indicators and Reagents; Microsomes, Liver; NADP; Nitriles; Oxidation-Reduction | 2007 |
The structure of human thioredoxin reductase 1 provides insights into C-terminal rearrangements during catalysis.
Topics: Animals; Binding Sites; Catalysis; Crystallography, X-Ray; Cysteine; Enzyme Inhibitors; Humans; Models, Molecular; Molecular Sequence Data; NADP; Oxidation-Reduction; Protein Structure, Quaternary; Thioredoxin Reductase 1; Thioredoxin-Disulfide Reductase | 2007 |
Reduction of vanadium(V) to vanadium(IV) by NADPH, and vanadium(IV) to vanadium(III) by cysteine methyl ester in the presence of biologically relevant ligands.
Topics: Cysteine; Dipeptides; Electron Spin Resonance Spectroscopy; Ligands; NADP; Oxidation-Reduction; Spectrophotometry, Ultraviolet; Vanadium | 2007 |
Hydrogen sulfide inhibits activity of three isoforms of recombinant nitric oxide synthase.
Topics: Air Pollutants; Biopterins; Cysteine; Dithiothreitol; Enzyme Inhibitors; Humans; Hydrogen Sulfide; NADP; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Recombinant Proteins; Sulfates | 2007 |
Saturation transfer difference NMR studies on substrates and inhibitors of succinic semialdehyde dehydrogenases.
Topics: Alanine; Aldehydes; Animals; Binding Sites; Cloning, Molecular; Cysteine; Drosophila Proteins; Enzyme Inhibitors; Escherichia coli Proteins; gamma-Aminobutyric Acid; Hydrocarbons, Aromatic; NAD; NADP; Nuclear Magnetic Resonance, Biomolecular; Substrate Specificity; Succinate-Semialdehyde Dehydrogenase | 2008 |
Purification and characterization of flavin-containing monooxygenase isoform 3 from rat kidney microsomes.
Topics: Amino Acid Sequence; Animals; Catalysis; Cysteine; Kidney; Kinetics; Male; Methimazole; Methionine; Microsomes; Molecular Sequence Data; Molecular Weight; NADP; Oxygenases; Rats; Rats, Sprague-Dawley; Selenomethionine; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Stereoisomerism | 2008 |
Mycothiol disulfide reductase: a continuous assay for slow time-dependent inhibitors.
Topics: Cysteine; Enzyme Assays; Enzyme Inhibitors; Glycopeptides; Inositol; Kinetics; NADH, NADPH Oxidoreductases; NADP; Recombinant Proteins; Substrate Specificity; Sulfhydryl Compounds; Time Factors | 2009 |
Insights into the alkyl peroxide reduction pathway of Xanthomonas campestris bacterioferritin comigratory protein from the trapped intermediate-ligand complex structures.
Topics: Amino Acid Sequence; Bacterial Proteins; Catalytic Domain; Cysteine; Escherichia coli Proteins; Ligands; Models, Molecular; Molecular Sequence Data; NADP; Oxidation-Reduction; Periplasmic Proteins; Peroxidases; Peroxides; Peroxiredoxins; Protein Structure, Secondary; Sequence Alignment; Structural Homology, Protein; Substrate Specificity; Thioredoxins; Xanthomonas campestris | 2009 |
The multifunctional enzyme CYP71B15 (PHYTOALEXIN DEFICIENT3) converts cysteine-indole-3-acetonitrile to camalexin in the indole-3-acetonitrile metabolic network of Arabidopsis thaliana.
Topics: Arabidopsis; Arabidopsis Proteins; Cyanides; Cysteine; Cytochrome P-450 Enzyme System; Indoles; Mass Spectrometry; Metabolomics; NADP; Thiazoles | 2009 |
From proteomics to structural studies of cytosolic/mitochondrial-type thioredoxin systems in barley seeds.
Topics: Catalysis; Cysteine; Cytosol; Gene Expression Regulation, Plant; Hordeum; Mitochondria; NADP; Plant Proteins; Protein Isoforms; Proteome; Proteomics; Seeds; Thioredoxin-Disulfide Reductase; Thioredoxins | 2009 |
Multiple redox and non-redox interactions define 2-Cys peroxiredoxin as a regulatory hub in the chloroplast.
Topics: Adenosine Triphosphate; Chloroplasts; Cysteine; DNA Primers; Fluorescence Resonance Energy Transfer; Kinetics; Light; NADP; Oxidation-Reduction; Oxidative Stress; Peroxiredoxins; Phosphorylation; Photosynthesis; Photosystem I Protein Complex; Transcription, Genetic | 2009 |
Cysteine as a modulator residue in the active site of xenobiotic reductase A: a structural, thermodynamic and kinetic study.
Topics: Alanine; Amino Acid Sequence; Amino Acid Substitution; Binding Sites; Coumarins; Cysteine; Kinetics; Molecular Sequence Data; Mutagenesis, Site-Directed; NAD; NADP; Oxidation-Reduction; Oxidoreductases; Protein Conformation; Pseudomonas putida; Serine; Substrate Specificity; Thermodynamics; Xenobiotics | 2010 |
Functional analysis of the pathways for 2-Cys peroxiredoxin reduction in Arabidopsis thaliana chloroplasts.
Topics: Antioxidants; Arabidopsis; Arabidopsis Proteins; Chloroplasts; Cysteine; Darkness; Hydrogen Peroxide; Light; NADP; Oxidation-Reduction; Oxidative Stress; Peroxiredoxins; Photosynthesis; Thioredoxin-Disulfide Reductase; Thioredoxins | 2010 |
Effects of selenite and chelating agents on mammalian thioredoxin reductase inhibited by mercury: implications for treatment of mercury poisoning.
Topics: Animals; Biocatalysis; Catalytic Domain; Cell Survival; Chelating Agents; Cysteine; Dose-Response Relationship, Drug; Enzyme Activation; Glutathione; HEK293 Cells; Humans; Mercuric Chloride; Mercury; Mercury Compounds; Mercury Poisoning; Methylmercury Compounds; Molecular Structure; NADP; Rats; Recombinant Proteins; Selenium Compounds; Selenocysteine; Sodium Selenite; Spectrometry, Mass, Electrospray Ionization; Thioredoxin-Disulfide Reductase | 2011 |
The role of Cys-298 in aldose reductase function.
Topics: Aldehyde Reductase; Amino Acid Substitution; Catalytic Domain; Crystallography, X-Ray; Cysteine; Diabetes Mellitus; Enzyme Activation; Humans; Hydrogen Bonding; Mutation, Missense; NADP; Oxidation-Reduction; Protein Structure, Tertiary | 2011 |
Glutathione modulates the toxicity of, but is not a biologically relevant reductant for, the Pseudomonas aeruginosa redox toxin pyocyanin.
Topics: Acetylcysteine; Cell Division; Cells, Cultured; Cysteine; Electron Spin Resonance Spectroscopy; Glutathione; Humans; NADP; Oxidation-Reduction; Pseudomonas aeruginosa; Pyocyanine; Reactive Oxygen Species | 2011 |
Biodiversity in sulfur metabolism in hemiascomycetous yeasts.
Topics: Amino Acids, Sulfur; Biodiversity; Cysteine; Genetic Variation; Glucosephosphate Dehydrogenase; Glutathione; Heme; Homocysteine; Methionine; NADP; Phylogeny; Sequence Alignment; Sequence Analysis, Protein; Sulfur; Yeasts | 2011 |
Characterization of short-lived electrophilic metabolites of the anticancer agent laromustine (VNP40101M).
Topics: Acetylcysteine; Antineoplastic Agents; Carbon Isotopes; Chromatography, High Pressure Liquid; Cysteine; Glutathione; Humans; Hydrazines; Magnetic Resonance Spectroscopy; Microsomes, Liver; NADP; Neoplasms; Spectrometry, Mass, Electrospray Ionization; Sulfonamides | 2011 |
Redox chemistry of the Schizosaccharomyces pombe ferredoxin electron-transfer domain and influence of Cys to Ser substitutions.
Topics: Amino Acid Substitution; Circular Dichroism; Cysteine; Ferredoxin-NADP Reductase; Ferredoxins; Iron-Sulfur Proteins; Mutagenesis, Site-Directed; NADP; Oxidation-Reduction; Schizosaccharomyces; Schizosaccharomyces pombe Proteins; Serine; Thermodynamics | 2011 |
Novel NADPH-cysteine covalent adduct found in the active site of an aldehyde dehydrogenase.
Topics: Aldehyde Dehydrogenase; Bacterial Proteins; Betaine-Aldehyde Dehydrogenase; Catalytic Domain; Crystallography, X-Ray; Cysteine; DNA Adducts; NADP; Pseudomonas aeruginosa | 2011 |
Atypical thioredoxins in poplar: the glutathione-dependent thioredoxin-like 2.1 supports the activity of target enzymes possessing a single redox active cysteine.
Topics: Amino Acid Sequence; Base Sequence; Catalytic Domain; Chloroplast Proteins; Cysteine; Cytosol; Dithionitrobenzoic Acid; Enzyme Activation; Gene Expression Profiling; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Plant; Genes, Plant; Glutaredoxins; Glutathione; Iron-Sulfur Proteins; Molecular Sequence Data; Mutagenesis, Site-Directed; NADP; Oxidation-Reduction; Oxidoreductases; Plant Cells; Plant Proteins; Plastids; Populus; Protein Isoforms; Recombinant Fusion Proteins; Solubility; Spectrometry, Mass, Electrospray Ionization; Substrate Specificity; Thioredoxin-Disulfide Reductase; Thioredoxins | 2012 |
S-glutathionylation regulates GTP-binding of Rac2.
Topics: Animals; Cysteine; Dithiothreitol; Enzyme Activation; Glutathione; Guanosine Triphosphate; NADP; rac GTP-Binding Proteins; RAC2 GTP-Binding Protein; Recombinant Proteins | 2012 |
Novel bioactivation mechanism of reactive metabolite formation from phenyl methyl-isoxazoles.
Topics: Carbamates; Carbon; Cysteine; Glutathione; Humans; Isoxazoles; Liver; Magnetic Resonance Spectroscopy; Mass Spectrometry; Microsomes, Liver; NADP; NAV1.1 Voltage-Gated Sodium Channel; Nitrogen; Oxidation-Reduction; Urea; Voltage-Gated Sodium Channel Blockers | 2012 |
A surprising observation that oxygen can affect the product enantiopurity of an enzyme-catalysed reaction.
Topics: Catalysis; Cycloparaffins; Cysteine; Hydrogen Peroxide; Hydrogen-Ion Concentration; Kinetics; Methionine; NADP; Nitroparaffins; Oxidoreductases; Oxygen; Propane; Reactive Oxygen Species; Spectrometry, Mass, Electrospray Ionization; Stereoisomerism; Superoxides | 2012 |
Comparative molecular modeling study of Arabidopsis NADPH-dependent thioredoxin reductase and its hybrid protein.
Topics: Amino Acid Sequence; Arabidopsis; Arabidopsis Proteins; Catalytic Domain; Cysteine; Electron Transport; Electrons; Flavin-Adenine Dinucleotide; Isoenzymes; Molecular Chaperones; Molecular Dynamics Simulation; Molecular Sequence Data; NADP; Protein Structure, Tertiary; Recombinant Fusion Proteins; Structure-Activity Relationship; Thioredoxin-Disulfide Reductase | 2012 |
The mechanism of discrimination between oxidized and reduced coenzyme in the aldehyde dehydrogenase domain of Aldh1l1.
Topics: Aldehyde Dehydrogenase; Catalysis; Catalytic Domain; Coenzymes; Crystallography, X-Ray; Cysteine; NADP; Oxidation-Reduction; Oxidoreductases Acting on CH-NH Group Donors; Protein Structure, Tertiary | 2013 |
Metabolic pathways leading to detoxification of triptolide, a major active component of the herbal medicine Tripterygium wilfordii.
Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Buthionine Sulfoximine; Cysteine; Cytochrome P-450 Enzyme System; Dipeptides; Diterpenes; Enzyme Inhibitors; Epoxy Compounds; Glutathione; Humans; Inactivation, Metabolic; Male; Metabolic Networks and Pathways; Mice; Microsomes, Liver; NADP; Phenanthrenes; Plants, Medicinal; Triazoles; Tripterygium | 2014 |
A single amino acid determines the catalytic efficiency of two alkenal double bond reductases produced by the liverwort Plagiochasma appendiculatum.
Topics: Aldehydes; Amino Acid Sequence; Biocatalysis; Cysteine; Escherichia coli; Hepatophyta; Kinetics; Molecular Docking Simulation; Molecular Sequence Data; Mutagenesis, Site-Directed; NADP; Oxidoreductases; Phylogeny; Plant Proteins; Recombinant Proteins; Sequence Alignment; Sequence Homology, Amino Acid; Substrate Specificity; Tyrosine | 2013 |
Expanding the paradigm of thiol redox in the thermophilic root of life.
Topics: Adaptation, Physiological; Chromatography, Liquid; Cysteine; Disulfides; Electrophoresis, Gel, Two-Dimensional; Glutathione; Hot Temperature; Metabolome; NADP; Oxidation-Reduction; Oxidative Stress; Proteins; Proteome; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Sulfolobus solfataricus | 2014 |
Importance of bacillithiol in the oxidative stress response of Staphylococcus aureus.
Topics: Amidohydrolases; Analysis of Variance; Anti-Bacterial Agents; Bacterial Proteins; Cysteine; Glucosamine; Glycosyltransferases; Hydrogen Peroxide; Microarray Analysis; Microbial Sensitivity Tests; Mutation; NADP; Oxidative Stress; Peroxidase; Staphylococcus aureus; Xanthophylls | 2014 |
Mycothiol/mycoredoxin 1-dependent reduction of the peroxiredoxin AhpE from Mycobacterium tuberculosis.
Topics: Bacterial Proteins; Biocatalysis; Cysteine; Disulfides; Glycopeptides; Hydrogen Peroxide; Hydrogen-Ion Concentration; Inositol; Kinetics; Models, Biological; Mycobacterium tuberculosis; NADP; Oxidation-Reduction; Peroxiredoxins | 2014 |
Thioredoxin-related protein of 14 kDa is an efficient L-cystine reductase and S-denitrosylase.
Topics: Carcinoma, Squamous Cell; Cysteine; Cystine; Enzyme Activation; Glutathione; HEK293 Cells; HT29 Cells; Humans; Hydrogen Peroxide; Lung Neoplasms; NADH, NADPH Oxidoreductases; NADP; Nitric Oxide; Oxidants; Oxidation-Reduction; Oxidative Stress; Substrate Specificity; Sulfur; Thioredoxin Reductase 1; Thioredoxins | 2014 |
External cys/cySS redox state modification controls the intracellular redox state and neurodegeneration via Akt in aging and Alzheimer's disease mouse model neurons.
Topics: Aging; Alzheimer Disease; Animals; Cell Death; Cells, Cultured; Cysteine; Cystine; Disease Models, Animal; Extracellular Space; Glutathione; Male; Mice; Mice, Transgenic; NADP; Neurons; Oxidation-Reduction; Proto-Oncogene Proteins c-akt; Reactive Oxygen Species | 2014 |
Structural studies of cinnamoyl-CoA reductase and cinnamyl-alcohol dehydrogenase, key enzymes of monolignol biosynthesis.
Topics: Alcohol Oxidoreductases; Aldehyde Oxidoreductases; Binding Sites; Biocatalysis; Cloning, Molecular; Crystallography, X-Ray; Cysteine; Disulfides; Esters; Kinetics; Ligands; Lignin; Medicago truncatula; Models, Molecular; Mutant Proteins; NADP; Petunia; Propanols; Structural Homology, Protein; Substrate Specificity; Temperature | 2014 |
Selective silencing of 2Cys and type-IIB Peroxiredoxins discloses their roles in cell redox state and stress signaling.
Topics: Abscisic Acid; Anthocyanins; Biosynthetic Pathways; Carotenoids; Chlorophyll; Chloroplasts; Cysteine; Cytosol; Fluorescence; Gene Expression Regulation, Plant; Gene Silencing; Genes, Plant; Glutathione; Hydrogen Peroxide; NADP; Nicotiana; Oxidation-Reduction; Oxidative Stress; Peroxiredoxins; Phenotype; Phosphoprotein Phosphatases; Photosystem II Protein Complex; Plant Leaves; Real-Time Polymerase Chain Reaction; Signal Transduction; Stress, Physiological | 2015 |
Evaluation of N-acetyl-S-(p-chlorophenylcarbamoyl)cysteine as an irreversible inhibitor of mammalian thioredoxin reductase1.
Topics: Cell Line, Tumor; Cysteine; Dialysis; Dose-Response Relationship, Drug; Enzyme Inhibitors; Humans; Mass Spectrometry; Melanoma; NADP; Sulfonylurea Compounds; Thioredoxin Reductase 1; Thioredoxin-Disulfide Reductase | 2016 |
The Methanosarcina acetivorans thioredoxin system activates DNA binding of the redox-sensitive transcriptional regulator MsvR.
Topics: Anaerobiosis; Archaeal Proteins; Cysteine; Disulfides; DNA; Gene Expression Regulation, Archaeal; Hydrogen Peroxide; Methanosarcina; NADP; Oxidants; Oxidation-Reduction; Promoter Regions, Genetic; Protein Binding; Sulfhydryl Compounds; Thioredoxin-Disulfide Reductase; Thioredoxins; Transcription Factors; Transcription, Genetic | 2015 |
Oxidation of structural cysteine residues in thioredoxin 1 by aromatic arsenicals enhances cancer cell cytotoxicity caused by the inhibition of thioredoxin reductase 1.
Topics: Arsenicals; Blotting, Western; Cell Survival; Cysteine; Cytosol; Humans; NADP; Neuroblastoma; Oxidation-Reduction; Peroxiredoxins; Reactive Oxygen Species; Real-Time Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Signal Transduction; Thioredoxin Reductase 1; Thioredoxins; Tumor Cells, Cultured | 2015 |
Redox regulation of metabolic and signaling pathways by thioredoxin and glutaredoxin in NOS-3 overexpressing hepatoblastoma cells.
Topics: Caspase 3; Caspase 8; Cell Proliferation; Cell Survival; Cysteine; fas Receptor; Gene Expression Regulation, Neoplastic; Glutaredoxins; Hep G2 Cells; Humans; NADP; Nitric Oxide; Nitric Oxide Synthase Type III; Oxidation-Reduction; Phosphorylation; Proto-Oncogene Proteins c-akt; RNA, Small Interfering; Signal Transduction; Thioredoxins | 2015 |
Nicotinamide Cofactors Suppress Active-Site Labeling of Aldehyde Dehydrogenases.
Topics: Acetamides; Aldehyde Dehydrogenase; Arabidopsis; Arabidopsis Proteins; Benzamides; Benzodioxoles; Catalytic Domain; Copper; Cysteine; Enzyme Assays; Fluorescent Dyes; Humans; Isoflavones; Molecular Docking Simulation; NAD; NADP; Oxidation-Reduction; Rhodamines; S-Nitrosoglutathione | 2016 |
Inhibitory nitrosylation of mammalian thioredoxin reductase 1: Molecular characterization and evidence for its functional role in cellular nitroso-redox imbalance.
Topics: Amino Acid Sequence; Animals; Catalytic Domain; Cysteine; Glutathione; HeLa Cells; Humans; NADP; Nitric Oxide Donors; Oxidation-Reduction; Protein Processing, Post-Translational; Rats; S-Nitrosothiols; Selenocysteine; Thioredoxin Reductase 1 | 2016 |
Control of Autophagy in Chlamydomonas Is Mediated through Redox-Dependent Inactivation of the ATG4 Protease.
Topics: Autophagy; Chlamydomonas; Conserved Sequence; Cysteine; Disulfides; Enzyme Activation; Light; Models, Biological; Mutation; NADP; Oxidation-Reduction; Plant Proteins; Protein Aggregates; Protein Multimerization; Serine; Stress, Physiological; Structure-Activity Relationship; Thioredoxins | 2016 |
Structural and Functional Characterization of Plasmodium falciparum Nicotinic Acid Mononucleotide Adenylyltransferase.
Topics: Catalytic Domain; Crystallography, X-Ray; Cysteine; Models, Molecular; NAD; NADP; Nicotinamide Mononucleotide; Nicotinamide-Nucleotide Adenylyltransferase; Plasmodium falciparum; Protein Conformation; Substrate Specificity; Surface Plasmon Resonance | 2016 |
Proteome analysis reveals differential expression of proteins involved in triacylglycerol accumulation by Rhodococcus jostii RHA1 after addition of methyl viologen.
Topics: Acyl Coenzyme A; Adaptation, Physiological; Catalase; Cysteine; Fatty Acids; Glycopeptides; Inositol; NADP; Nitrogen; Oxidation-Reduction; Oxidative Stress; Oxidoreductases; Paraquat; Peroxiredoxins; Proteome; Rhodococcus; Superoxide Dismutase; Triglycerides | 2017 |
Restricting the conformational freedom of the neuronal nitric-oxide synthase flavoprotein domain reveals impact on electron transfer and catalysis.
Topics: Animals; Calmodulin; Catalysis; Cross-Linking Reagents; Cysteine; Cytochromes c; Disulfides; Electrons; Flavins; Flavoproteins; Hydrogen-Ion Concentration; Kinetics; Maleimides; Mutation; NADP; Nitric Oxide; Nitric Oxide Synthase Type I; Oxidation-Reduction; Protein Domains; Rats; Spectrophotometry, Ultraviolet; Sulfhydryl Compounds | 2017 |
Cysteine-Containing Peptides Stimulate Monocyte Migration through NADPH-Oxidase Activation.
Topics: Cell Movement; Cells, Cultured; Chemokine CCL2; Chemokine CX3CL1; Cysteine; Humans; MAP Kinase Signaling System; Monocytes; NADP; NADPH Oxidases; Peptides; Reactive Oxygen Species | 2017 |
Substrate-induced structural alterations of Mycobacterial mycothione reductase and critical residues involved.
Topics: Cysteine; Glycopeptides; Inositol; Models, Molecular; Mutation; Mycobacterium tuberculosis; NADP; Oxidation-Reduction; Oxidoreductases; Protein Binding; Protein Multimerization; Protein Structure, Quaternary | 2018 |
Selective determination of the catalytic cysteine pK
Topics: Acinetobacter baumannii; Amino Acid Sequence; Amino Acid Substitution; Bacterial Proteins; Biocatalysis; Catalytic Domain; Crystallography, X-Ray; Cysteine; gamma-Aminobutyric Acid; Hydrogen-Ion Concentration; Kinetics; NADP; Sequence Homology, Amino Acid; Substrate Specificity; Succinate-Semialdehyde Dehydrogenase | 2018 |
NADP
Topics: Animals; Cadmium; Calorimetry; Chelating Agents; Crystallography, X-Ray; Cysteine; Cytosol; Dithiothreitol; Enzyme Activation; Glutathione; Isocitrate Dehydrogenase; Mice; NADP; Protein Conformation; Spectrophotometry, Ultraviolet | 2018 |
Structural and Functional Studies of the Membrane-Binding Domain of NADPH-Cytochrome P450 Oxidoreductase.
Topics: Catalytic Domain; Cell Membrane; Crystallography, X-Ray; Cysteine; Cytochrome P-450 Enzyme System; Electron Transport; Escherichia coli; Flavoproteins; Hydrophobic and Hydrophilic Interactions; Kinetics; Lipid Bilayers; Liposomes; NADP; NADPH-Ferrihemoprotein Reductase; Oxidoreductases, N-Demethylating; Plasmids; Protein Structure, Tertiary; Sequence Analysis, Protein | 2019 |
A Regulatory Cysteine Residue Mediates Reversible Inactivation of NAD
Topics: Aldehyde Dehydrogenase; Catalysis; Catalytic Domain; Cysteine; Models, Molecular; NAD; NADP; Oxidation-Reduction; Oxidative Stress; Signal Transduction | 2020 |
Unexpected NADPH Hydratase Activity in the Nitrile Reductase QueF from Escherichia coli.
Topics: Catalysis; Cysteine; Escherichia coli; Escherichia coli Proteins; Hydro-Lyases; Mutagenesis, Site-Directed; Mutation; NADP; Nitriles; Oxidoreductases | 2020 |
A synthetic lethal drug combination mimics glucose deprivation-induced cancer cell death in the presence of glucose.
Topics: Amino Acid Transport System y+; Antineoplastic Combined Chemotherapy Protocols; Antiporters; Cell Death; Cell Line, Tumor; Cell Survival; Cysteine; Cystine; Dimerization; Glucose; Glucose Transporter Type 1; Glutamic Acid; Glutathione; Humans; Metabolome; NADP; Neoplasms; Oxidation-Reduction; Reactive Oxygen Species; Synthetic Drugs | 2020 |
3,6-Anhydro-L-Galactose Dehydrogenase VvAHGD is a Member of a New Aldehyde Dehydrogenase Family and Catalyzes by a Novel Mechanism with Conformational Switch of Two Catalytic Residues Cysteine 282 and Glutamate 248.
Topics: Amino Acid Sequence; Binding Sites; Catalysis; Cysteine; Galactose; Galactose Dehydrogenases; Glutamic Acid; Models, Molecular; Mutation; NADP; Phylogeny; Sequence Homology; Vibrio | 2020 |
Structure and function of a flavin-dependent S-monooxygenase from garlic (
Topics: Biopolymers; Cysteine; Disulfides; Flavin-Adenine Dinucleotide; Garlic; Hydrogen Peroxide; Hydroxylation; Kinetics; NADP; Oxidation-Reduction; Oxygenases; Protein Conformation; Structure-Activity Relationship; Substrate Specificity; Sulfinic Acids | 2020 |
The Crystal Structures of Bacillithiol Disulfide Reductase Bdr (YpdA) Provide Structural and Functional Insight into a New Type of FAD-Containing NADPH-Dependent Oxidoreductase.
Topics: Bacillus cereus; Bacterial Proteins; Crystallography, X-Ray; Cysteine; Flavin-Adenine Dinucleotide; Glucosamine; NADP; Oxidation-Reduction; Oxidoreductases Acting on Sulfur Group Donors; Protein Structure, Quaternary; Staphylococcus aureus | 2020 |
Covalent inhibition of P. falciparum ferredoxin-NADP
Topics: Antineoplastic Agents, Alkylating; Biocatalysis; Carmustine; Catalytic Domain; Cysteine; Diamide; Enzyme Inhibitors; Ferredoxin-NADP Reductase; Kinetics; Malaria, Falciparum; Molecular Structure; NADP; Organomercury Compounds; Plasmodium falciparum; Protein Binding; Protein Domains; Protozoan Proteins; Substrate Specificity | 2021 |
A conserved sequence motif in the Escherichia coli soluble FAD-containing pyridine nucleotide transhydrogenase is important for reaction efficiency.
Topics: Amino Acid Motifs; Amino Acid Sequence; Conserved Sequence; Cysteine; Escherichia coli Proteins; Flavoproteins; Hydrogen Peroxide; NAD; NADP; NADP Transhydrogenase, B-Specific; Niacinamide; Oxygen; Superoxides; Threonine | 2022 |
New insights on low-temperature storage regulating garlic greening and the accumulation of pigment precursors via glutathione metabolism and energy cycles.
Topics: Antioxidants; Color; Cysteine; Garlic; Glutathione; NADP; Pigments, Biological; Temperature | 2023 |