cysteine and monocrotaline

cysteine has been researched along with monocrotaline in 17 studies

Research

Studies (17)

TimeframeStudies, this research(%)All Research%
pre-19904 (23.53)18.7374
1990's5 (29.41)18.2507
2000's3 (17.65)29.6817
2010's2 (11.76)24.3611
2020's3 (17.65)2.80

Authors

AuthorsStudies
Allen, JR; Hsia, MT; Robertson, KA; Seymour, JL1
Bowers, R; Huxtable, RJ; Mattocks, AR; Michnicka, M1
Cheeke, PR; Garrett, BJ1
Buhler, DR; Cheeke, PR; Miranda, CL; Reed, RL1
Buhler, DR; Carpenter, HM; Cheeke, PR; Miranda, CL1
Huxtable, RJ; Yan, CC3
Jones, AD; Lamé, MW; Pan, LC; Segall, HJ; Wilson, DW1
Górniak, SL; Guerra, JL; Medeiros, RM; Soto-Blanco, B1
Coulombe, RA; Rieben, WK1
Jones, AD; Lamé, MW; Segall, HJ; Wilson, DW1
Fu, PP; He, X; Ma, L; Xia, Q1
Bu, D; Chen, S; Du, J; Huang, Y; Jin, H; Kong, W; Liu, X; Tang, C; Tang, X; Tao, Y; Wang, X; Yang, G; Yu, W; Zhang, D; Zhang, H1
Fu, PP; He, X; Shi, Q; Xia, Q1
Guo, J; Huo, S; Li, S; Lin, L; Luo, P; Lv, J; Peng, L; Shi, W; Wang, M; Yan, D; Zhang, C1
Chen, S; Cui, H; Du, GQ; Li, Y; Shen, W; Sun, P; Wang, C; Xue, JY; Zhao, P1

Reviews

1 review(s) available for cysteine and monocrotaline

ArticleYear
Sulfur conjugates as putative pneumotoxic metabolites of the pyrrolizidine alkaloid, monocrotaline.
    Advances in experimental medicine and biology, 1991, Volume: 283

    Topics: Animals; Biotransformation; Cysteine; Glutathione; Liver; Lung; Monocrotaline; Pyrrolizidine Alkaloids; Rats

1991

Other Studies

16 other study(ies) available for cysteine and monocrotaline

ArticleYear
Covalent interaction of dehydroretronecine, a carcinogenic metabolite of the pyrrolizidine alkaloid monocrotaline, with cysteine and glutathione.
    Cancer research, 1977, Volume: 37, Issue:9

    Topics: Alkylation; Binding Sites; Carcinogens; Chemical Phenomena; Chemistry; Chromatography; Cysteine; Glutathione; In Vitro Techniques; Magnetic Resonance Spectroscopy; Monocrotaline; Pyrrolizidine Alkaloids; Spectrum Analysis; Sulfhydryl Compounds

1977
Evaluation of amino acids, B vitamins and butylated hydroxyanisole as protective agents against pyrrolizidine alkaloid toxicity in rats.
    Journal of animal science, 1984, Volume: 58, Issue:1

    Topics: Amino Acids; Animal Feed; Animals; Anisoles; Body Weight; Butylated Hydroxyanisole; Cysteine; Folic Acid; Food, Fortified; Male; Monocrotaline; Plant Poisoning; Plants, Toxic; Pyrrolizidine Alkaloids; Rats; Rats, Inbred Strains; Rodent Diseases; Senecio; Vitamin B 12; Vitamin B Complex

1984
Protective effects of butylated hydroxyanisole against the acute toxicity of monocrotaline in mice.
    Toxicology and applied pharmacology, 1981, Volume: 59, Issue:3

    Topics: Animals; Butylated Hydroxytoluene; Cysteine; Cytosol; Diet; Glutathione Transferase; In Vitro Techniques; Mice; Microsomes, Liver; Mixed Function Oxygenases; Monocrotaline; Pyrrolizidine Alkaloids; Sulfhydryl Compounds

1981
Effect of ethoxyquin on the toxicity of the pyrrolizidine alkaloid monocrotaline and on hepatic drug metabolism in mice.
    Chemico-biological interactions, 1981, Volume: 37, Issue:1-2

    Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Cysteine; Cytochrome P-450 Enzyme System; Dinitrochlorobenzene; Ethoxyquin; Female; Glutathione; Glutathione Transferase; Liver; Mice; Monocrotaline; Pyrrolizidine Alkaloids; Quinolines

1981
Effect of the pyrrolizidine alkaloid, monocrotaline, on bile composition of the isolated, perfused rat liver.
    Life sciences, 1995, Volume: 57, Issue:6

    Topics: Amino Acids; Animals; Bile; Cysteine; Dipeptides; Glutathione; In Vitro Techniques; Monocrotaline; Pyrroles; Rats; Rats, Sprague-Dawley

1995
COR pulmonale is caused by monocrotaline and dehydromonocrotaline, but not by glutathione or cysteine conjugates of dihydropyrrolizine.
    Toxicology and applied pharmacology, 1993, Volume: 118, Issue:1

    Topics: Animals; Body Weight; Cysteine; Glutathione; Lung; Male; Monocrotaline; Pulmonary Heart Disease; Rats; Rats, Sprague-Dawley

1993
Effects of taurine and guanidinoethane sulfonate on toxicity of the pyrrolizidine alkaloid monocrotaline.
    Biochemical pharmacology, 1996, Feb-09, Volume: 51, Issue:3

    Topics: Amino Acids; Animals; Body Weight; Cysteine; Glutathione; Liver; Male; Monocrotaline; Organ Size; Rats; Rats, Sprague-Dawley; Taurine

1996
Effect of taurine on biliary metabolites of glutathione in liver perfused with the pyrrolizidine alkaloid, monocrotaline.
    Advances in experimental medicine and biology, 1998, Volume: 442

    Topics: Animals; Bile; Cysteine; Dipeptides; Glutathione; Liver; Male; Molecular Structure; Monocrotaline; Perfusion; Rats; Rats, Sprague-Dawley; Taurine; Toxins, Biological

1998
Lack of protective action of cysteine against the fetotoxic effect of monocrotaline.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2001, Volume: 39, Issue:7

    Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Body Weight; Creatinine; Cysteine; Eating; Female; Fetal Death; Fetus; Male; Monocrotaline; Organ Size; Plant Extracts; Poisoning; Pregnancy; Rats; Rats, Wistar; Treatment Failure; Urea

2001
DNA cross-linking by dehydromonocrotaline lacks apparent base sequence preference.
    Toxicological sciences : an official journal of the Society of Toxicology, 2004, Volume: 82, Issue:2

    Topics: Amino Acids; Aspartic Acid; Base Sequence; Chromatography, High Pressure Liquid; Cross-Linking Reagents; Cysteine; DNA; Electrophoretic Mobility Shift Assay; Glutathione; Indicators and Reagents; Monocrotaline; Nucleic Acid Denaturation; Oligonucleotides; Pyrroles; Tyrosine

2004
Monocrotaline pyrrole targets proteins with and without cysteine residues in the cytosol and membranes of human pulmonary artery endothelial cells.
    Proteomics, 2005, Volume: 5, Issue:17

    Topics: Amino Acid Sequence; Cells, Cultured; Colloids; Cross-Linking Reagents; Cysteine; Electrophoresis, Gel, Two-Dimensional; Endothelium, Vascular; Heat-Shock Proteins; Humans; Molecular Sequence Data; Monocrotaline; Peptide Fragments; Protein Disulfide-Isomerases; Proteins; Pulmonary Artery; Silicon Dioxide; Tropomyosin

2005
7-cysteine-pyrrole conjugate: A new potential DNA reactive metabolite of pyrrolizidine alkaloids.
    Journal of environmental science and health. Part C, Environmental carcinogenesis & ecotoxicology reviews, 2016, Volume: 34, Issue:1

    Topics: Animals; Cysteine; DNA; DNA Adducts; Glutathione; Humans; Male; Microsomes, Liver; Monocrotaline; Pyrrolizidine Alkaloids; Rats, Inbred F344; Tandem Mass Spectrometry

2016
Endogenous hydrogen sulfide sulfhydrates IKKβ at cysteine 179 to control pulmonary artery endothelial cell inflammation.
    Clinical science (London, England : 1979), 2019, 10-30, Volume: 133, Issue:20

    Topics: Animals; Cells, Cultured; Cysteine; Cytokines; Down-Regulation; Endothelial Cells; Endothelium, Vascular; Humans; Hydrogen Sulfide; Hypertension, Pulmonary; I-kappa B Kinase; Inflammation; Inflammation Mediators; Intercellular Adhesion Molecule-1; Male; Monocrotaline; NF-kappa B; Pulmonary Artery; Rats, Wistar; Signal Transduction

2019
Effects of glutathione and cysteine on pyrrolizidine alkaloid-induced hepatotoxicity and DNA adduct formation in rat primary hepatocytes.
    Journal of environmental science and health. Part C, Toxicology and carcinogenesis, 2020, Volume: 38, Issue:2

    Topics: Animals; Carcinogens; Chromatography, High Pressure Liquid; Cysteine; Glutathione; Male; Microsomes, Liver; Monocrotaline; Pyrrolizidine Alkaloids; Rats; Tandem Mass Spectrometry

2020
S-Nitroso-L-Cysteine Ameliorated Pulmonary Hypertension in the MCT-Induced Rats through Anti-ROS and Anti-Inflammatory Pathways.
    Oxidative medicine and cellular longevity, 2021, Volume: 2021

    Topics: Animals; Anti-Inflammatory Agents; Cell Line; Cell Movement; Collagen; Cysteine; Endoplasmic Reticulum Stress; Hemodynamics; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Lung; Male; MAP Kinase Signaling System; Matrix Metalloproteinases; Mitophagy; Monocrotaline; Muscle Contraction; Muscle, Smooth; Oxidative Stress; Phosphorylation; Rats, Sprague-Dawley; Reactive Oxygen Species; S-Nitrosothiols; STAT3 Transcription Factor; Vascular Remodeling; Wound Healing

2021
Melatonin activates the Mst1-Nrf2 signaling to alleviate cardiac hypertrophy in pulmonary arterial hypertension.
    European journal of pharmacology, 2022, Oct-15, Volume: 933

    Topics: Animals; Antioxidants; Arginine Vasopressin; Cysteine; Disease Models, Animal; Familial Primary Pulmonary Hypertension; Hepatocyte Growth Factor; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Malondialdehyde; Melatonin; Monocrotaline; NF-E2-Related Factor 2; Proto-Oncogene Proteins; Pulmonary Arterial Hypertension; Rats; RNA, Small Interfering; Ventricular Remodeling

2022