cysteine has been researched along with metallothionein in 227 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 71 (31.28) | 18.7374 |
| 1990's | 58 (25.55) | 18.2507 |
| 2000's | 50 (22.03) | 29.6817 |
| 2010's | 40 (17.62) | 24.3611 |
| 2020's | 8 (3.52) | 2.80 |
| Authors | Studies |
|---|---|
| Rupp, H; Weser, U | 1 |
| Kägi, JH; Kissling, MM; Kojima, Y; Lerch, K | 1 |
| Kaplan, BE; Kimura, M; Yoshida, A | 1 |
| Mogilnicka, EM; Piotrowski, JK | 1 |
| Bryan, SE; Hidalgo, HA; Koppa, V | 1 |
| Andersen, RD; Bernstein, IA; Maher, JJ; Winter, WP | 1 |
| Cherian, MG | 1 |
| Bakka, A; Beynon, PJ; Sadler, PJ | 1 |
| Bremner, I; Davies, NT; Hoekstra, G; Young, BW | 1 |
| Fukino, H; Imagawa, M; Yamane, Y | 1 |
| Berger, C; Kägi, JH; Kojima, Y; Vallee, BL | 1 |
| Chen, RW; Weswig, PH; Whanger, PD | 1 |
| Nordberg, GF; Nordberg, M; Piscator, M | 1 |
| Datz, FL; Jones, BJ; Lynch, RE; Morton, KA; Phelps, RC; Schaefer, AE; Sohn, MH | 1 |
| Baert, JL; Dhainaut-Courtois, N; Nejmeddine, A; Sautiere, P | 1 |
| Braun, W; Kägi, JH; Robbins, AH; Stout, CD; Vasák, M; Wagner, G; Wüthrich, K | 1 |
| Kimura, M | 1 |
| Armitage, IM; Chernaik, ML; Cismowski, MJ; Huang, PC; Narula, SS | 1 |
| Kimura, M; Koizumi, S; Otsuka, F | 1 |
| Hunziker, PE | 1 |
| Wüthrich, K | 1 |
| Esaki, N; Oikawa, T; Soda, K; Tanaka, H | 1 |
| Hunziker, PE; Kojima, Y | 1 |
| Aposhian, HV; Nelson, DL; Perry, DF; Zheng, W | 1 |
| Collett, SA; Furey, WF; McRee, DE; Robbins, AH; Stout, CD; Wang, BC; Williamson, M; Xuong, NH | 1 |
| Kawaguchi, S; Maita, Y | 1 |
| Raffaniello, RD; Wapnir, RA | 1 |
| Cismowski, MJ; Huang, PC | 1 |
| Biber, TU; Ford, GD; Lyall, V; Suzuki, Y | 1 |
| de Miranda, JR; Thomas, MA; Thurman, DA; Tomsett, AB | 1 |
| Armario, A; Garvey, JS; Hidalgo, J | 1 |
| Bartsch, R; Klein, D; Summer, KH | 1 |
| Gregus, Z; Howell, S; Klaassen, CD; Sendelbach, LE; White, CA | 1 |
| Imagawa, M; Kondo, M; Nishihara, T; Okumura, K; Onozawa, T; Osada, S | 1 |
| Barnes, DM; Klasing, KC; Laurin, DE | 1 |
| Hernandez, L; Issaq, HJ; Waalkes, MP; Wahba, ZZ | 1 |
| Jauch, A; Lutz, WK | 1 |
| Takahashi, K; Takita, T; Umezawa, H | 1 |
| Elder, RC; Nedelman, MA; Tepperman, K | 1 |
| Iguchi, S; Matsuno, Y; Min, KS; Nishiyama, Y; Okada, Y; Onosaka, S; Tanaka, K; Tsuda, Y | 1 |
| Freedman, JH; Peisach, J | 1 |
| Cherian, MG; Gallant, KR | 1 |
| Szczypka, MS; Thiele, DJ | 1 |
| Babin, D; Ebadi, M | 1 |
| Cherian, MG; DeAngelis, MV; Ohta, H | 1 |
| Müller, L; Stacey, NH | 2 |
| Overnell, J; Stone, H | 1 |
| Bas, J; Flos, R; Hidalgo, J | 1 |
| Clancy, LL; Furey, WF; Robbins, AH; Stout, CD; Wang, BC; Winge, DR | 2 |
| Braun, W; Frey, MH; Kägi, JH; Neuhaus, D; Vasak, M; Wagner, G; Wörgötter, E; Wüthrich, K | 1 |
| Armitage, IM; Dalgarno, DC; Johnson, BA | 1 |
| Weser, U | 1 |
| Bernhard, WR; Kägi, JH; Vasák, M | 1 |
| Hunziker, PE; Kägi, JH | 1 |
| Klaassen, CD; Waalkes, MP | 1 |
| Bernhard, WR; Kägi, JH | 1 |
| Lastowski-Perry, D; Maroni, G; Otto, E; Watson, D | 1 |
| Braun, W; Kägi, JH; Schultze, P; Vasák, M; Wagner, G; Wörgötter, E; Wüthrich, K | 1 |
| Krezoski, SK; Petering, DH; Shaw, CF; Villalobos, J | 1 |
| Byrd, J; Hamer, DH; Mehra, RK; Tarbet, EB; Thrower, AR; Winge, DR | 1 |
| Greenstock, CL; Jinot, CP; Sargent, MD; Whitehouse, RP | 1 |
| Hatta, A; Min, KS; Ohta, N; Okada, Y; Onosaka, S; Tanaka, K | 1 |
| Kägi, JH; Vasák, M; Wagner, G; Wörgötter, E; Wüthrich, K | 1 |
| Vasák, M | 1 |
| Brouwer, M; Engel, DW; Fowler, BA | 1 |
| Murakami, M; Nishikawa, M; Suzuki, KT; Takahara, T; Watanabe, H; Yamamura, M | 1 |
| Jin, T; Nordberg, GF; Nordberg, M | 1 |
| Bracken, WM; Klaassen, CD; Stein, AF | 1 |
| Atkins, LM; Fody, EP; Gale, GR; Smith, AB; Walker, EM | 1 |
| Bremner, I; Mehra, RK | 1 |
| Cherian, MG; Onosaka, S; Rodgers, K; Scheuhammer, AM | 1 |
| Maitani, T; Saito, Y; Suzuki, KT | 1 |
| Bracken, WM; Dudley, RE; Goering, PL; Hazelton, GA; Hjelle, JJ; Klaassen, CD | 1 |
| Girgis, GR; Kuliszewski, MJ; Nicholls, DM; Samji, S | 1 |
| Kägi, JH; Neuhaus, D; Vasák, M; Wagner, G; Wüthrich, K | 1 |
| Koizumi, T; Saito, S; Yamane, Y | 1 |
| Bernhard, WR; Gilg, DE; Good, M; Hunziker, P; Kägi, JH; Lerch, K; Vasák, M | 1 |
| Seagrave, J; Tobey, RA | 1 |
| Endresen, L; Jellum, E; Rugstad, HE; Thorsrud, AK; Willard-Gallo, KE | 1 |
| Ohta, N; Okada, Y; Tanaka, K | 1 |
| Clarke, R; Hunt, DM | 1 |
| Crane, IJ; Hunt, DM | 1 |
| Osborne, TR; Revis, NW | 1 |
| Camakaris, J; Danks, DM; Lazdins, I; Mercer, JF; Stevenson, T | 1 |
| Kawata, M; Suzuki, KT | 1 |
| Enger, MD; Hildebrand, CE; Stewart, CC | 1 |
| Huxtable, RJ; Lafranconi, WM | 1 |
| Gerson, RJ; Shaikh, ZA | 1 |
| Prins, HW; Van den Hamer, CJ | 1 |
| Deagen, JT; Oh, SH; Whanger, PD | 1 |
| Sato, M; Sugano, H; Takizawa, Y | 1 |
| Sharma, RP; Verma, MP | 1 |
| Cherian, MG; Ohta, H | 1 |
| Fujiwara, Y; Kaji, T; Kozuka, H; Machida, M; Mishima, A; Sakamoto, M; Suzuki, M; Yabusaki, K; Yamamoto, C | 1 |
| Albergoni, V; De Gabrieli, R; James, P; Piccinni, E; Staudenmann, W | 1 |
| Fenselau, C; Wu, Z; Yu, X | 1 |
| Cherian, MG; Imura, N; Satoh, M; Shimizu, H | 1 |
| Bill, E; Butzlaff, C; Ding, XQ; Henkel, G; Pountney, DL; Trautwein, AX; Vasák, M; Winkler, H | 1 |
| Cousins, RJ; Khoo, C | 1 |
| Gachot, B; Morat, L; Poujeol, P; Tauc, M; Wanstok, F | 1 |
| Bebianno, MJ; Langston, WJ | 1 |
| Armitage, IM; Narula, SS; Winge, DR | 1 |
| Bertini, I; Luchinat, C; Messori, L; Vasak, M | 1 |
| Hale, JE; Jue, RA | 1 |
| Danks, DM; Gahl, WA; Hahn, SH; Tanner, MS | 1 |
| Anderson, DM; Grula, JW; Hobbs, SL; Hudspeth, RL; Rajasekaran, K | 1 |
| Ali, SF; Hussain, S; Slikker, W | 1 |
| Jacobs, F; Luo, D; Mah, N; Martin, L; Wishart, D; Zhang, Y | 1 |
| Crawford, RL; Reynolds, TL | 1 |
| Kato, N; Wan, Q; Yamazaki, M; Yang, BS | 1 |
| Chang, CC; Huang, PC | 1 |
| Kojima, Y; Kurasaki, M; Yamaguchi, R | 1 |
| Endo, T; Kimura, O; Sakata, M | 1 |
| Litchfield, TM; Sauer, GR | 1 |
| Emoto, T; Kojima, Y; Kurasaki, M; Oikawa, S; Okabe, M; Yamasaki, F | 1 |
| Noujaim, AA; Sykes, TR; Wang, XB; Woo, TK; Xue, LY | 1 |
| Hiramoto, K; Kikugawa, K; Ojima, N | 1 |
| Ebadi, M; El Refaey, H; Hamada, FM; Hamed, A; Kuszynski, CA; Sweeney, J | 1 |
| Inoue, M; Kashiba, M; Kuroki, T; Nishikawa, M; Sato, EF; Utsumi, K | 1 |
| Chang, CC; Huang, PC; Liao, WF | 1 |
| Houki, N; Ichibangase, Y; Nobunaga, M; Yamamoto, M; Yasuda, M | 1 |
| Cao, Y; Yang, J; Yang, MS | 1 |
| Genkin, MV; Mikoyan, VD; Serezhenkov, VA; Vanin, AF | 1 |
| Atrian, S; Capdevila, M; Cols, N; Gelpí, JL; González-Duarte, P; González-Duarte, R; Romero-Isart, N; Termansen, MK | 1 |
| Huang, PC; Lyu, PC; Pan, PK; Zheng, ZF | 1 |
| Aravindakumar, CT; Ceulemans, J; De Ley, M | 2 |
| Brown, BW; Ward, KA | 1 |
| Fenselau, C; Szilágyi, Z | 1 |
| Bertini, I; Hartmann, HJ; Klein, T; Liu, G; Luchinat, C; Weser, U | 1 |
| Mader, P; Sestáková, I | 1 |
| Burlando, B; Ceratto, N; Panfoli, I; Viarengo, A | 1 |
| Gandley, R; Levitan, ES; Pearce, LL; Pitt, BR; St Croix, CM; Wasserloos, K | 1 |
| Hedley, DW; Pheng, SR; Stewart, A; Vik, CH; Vukovic, V | 1 |
| Berweger, CD; Thiel, W; van Gunsteren, WF | 1 |
| Garrison, G; George, GN; Heaton, DN; Winge, DR | 1 |
| Muñoz, A; Petering, DH; Shaw, CF | 1 |
| An, Y; Bi, R; Hou, T; Ru, B; Xu, X | 1 |
| Maret, W; Vallee, BL; Yang, Y | 1 |
| Gutteridge, JM; Moran, LK; Quinlan, GJ | 1 |
| Blindauer, CA; Cavet, JS; Harrison, MD; Parkinson, JA; Robinson, AK; Robinson, NJ; Sadler, PJ | 1 |
| Feldman, BM; Schenk, AD; Wilcox, DE; Xu, Y | 1 |
| Chen, Y; Maret, W | 1 |
| Armitage, IM; Otvos, JD; Oz, G; Shen, G; Zangger, K | 1 |
| Antholine, WE; Krepkiy, D; Myers, C; Petering, DH | 1 |
| Greven, H; Schmitt-Wrede, HP; Tschuschke, S; Wunderlich, F | 1 |
| Dineley, KE; Levitan, ES; Pitt, BR; Reynolds, IJ; St Croix, CM; Wasserloos, KJ | 1 |
| Ausseil, O; Lange, A; Segner, H | 1 |
| Bayir, H; Hubel, CA; Kagan, VE; Liu, SX; Tyurin, VA; Tyurina, YY | 1 |
| Giles, GI; Jacob, C; Tasker, KM | 1 |
| Blindauer, CA; Bowness, PW; Harrison, MD; Parkinson, JA; Robinson, AK; Robinson, NJ; Sadler, PJ | 1 |
| Gao, Y; Huang, ZX; Yang, PY; Yu, WH; Zhang, SY | 1 |
| Hong, SH; Maret, W | 1 |
| Chang, CC; Kan, LS; Lee, HT; Liu, YL | 1 |
| Kuroda, K; Ueda, M | 1 |
| Floriańczyk, B | 1 |
| Armitage, IM; Cobine, PA; Dameron, CT; McKay, RT; Zangger, K | 1 |
| Blindauer, CA; Sadler, PJ | 1 |
| Baynton-Smith, C; Fry, FH; Jacob, C; Kershaw, MJ; Okarter, N; Talbot, NJ | 1 |
| Akatsuka, S; Lee, WH; Miyagawa-Hayashino, A; Ozeki, M; Shirase, T; Toyokuni, S; Uchida, K | 1 |
| Hao, Q; Hong, SH; Maret, W | 1 |
| Binggen, R; Dian, Y; Jie, L; Kaifeng, S; Lin, A | 1 |
| Knecht, DA; Lynes, MA; Yin, X | 1 |
| Benz, FW; Cai, J; Feng, W; Kang, YJ; Pierce, WM | 1 |
| Ru, BG; Shen, GF; Zhang, YK | 1 |
| Hao, Q; Maret, W | 1 |
| Blindauer, CA; Campopiano, DJ; Razi, MT; Sadler, PJ | 1 |
| Andersen, RA; Kristiansen, E; Pedersen, SA; Zachariassen, KE | 1 |
| Hao, Q; Krezel, A; Maret, W | 1 |
| Blindauer, CA; Leszczyszyn, OI; Schmid, R | 1 |
| Algreen-Petersen, RG; Andersen, SU; Braunschweig, U; Cvitanich, C; Hoedl, M; Jensen, EØ; Jurkiewicz, A; Oh, SA; Schauser, L; Twell, D | 1 |
| Harding, PA; Hoskins, JT; Zhou, Z | 1 |
| Chen, CC; Chen, CY; Chen, JH; Chiu, YW; Jeng, YP; Liang, SH; Shieh, BS | 1 |
| He, X; Ma, Q | 1 |
| Ariyasu, S; Onoda, A; Sakamoto, R; Yamamura, T | 1 |
| Karotki, AV; Vasák, M | 1 |
| Ju, J; Kennett, MJ; Lambert, JD; Reuhl, KR; Sang, S; Yang, CS | 1 |
| Rajaram, A; Rajaram, R; Sankaramanivel, S | 1 |
| Alcaraz, LA; Cols, N; Donaire, A; González-Duarte, P; Serra-Batiste, M; Vasák, M | 1 |
| Krecisz, S; Ngu, TT; Stillman, MJ | 1 |
| Casini, A; Dyson, PJ; Gabbiani, C; Karotki, A; Messori, L; Rugi, F; Vašák, M | 1 |
| Hassinen, VH; Kärenlampi, SO; Schat, H; Tervahauta, AI | 1 |
| Goossens, L | 1 |
| Genzer, J; Hidasova, D; Srogl, J; Voltrova, S | 1 |
| Freisinger, E | 1 |
| Kepp, KP | 1 |
| Fernandez, LR; Goormaghtigh, E; Govaerts, C; Roosens, N; Vandenbussche, G; Verbruggen, N | 1 |
| Joshi, R; Karan, R; Kumar, G; Kumari, S; Kushwaha, HR; Mittal, S; Panjabi-Sabharwal, V; Pareek, A; Pareek, SL | 1 |
| Dryden, MD; Mahrok, AK; Stillman, MJ; Summers, KL | 1 |
| Isobe, M; Kaji, T; Kimura, T; Naka, H; Satoh, M; Suzuki, M; Uchiyama, M; Uno, T; Yamamoto, C; Yasuike, S; Yoshida, K | 1 |
| Enescu, M; Kassim, R; Ramseyer, C | 1 |
| Matranga, V; Russo, R; Zito, F | 1 |
| Irvine, GW; Stillman, MJ; Summers, KL | 1 |
| Delangle, P; Gateau, C; Jullien, AS; Kieffer, I; Testemale, D | 1 |
| Go, YM; Jones, DP; Orr, M | 1 |
| Bajt, ML; Jaeschke, H; Lebofsky, M; McGill, MR; Williams, CD | 1 |
| Garrett, SH; Mehus, AA; Muhonen, WW; Sens, DA; Shabb, JB; Somji, S | 1 |
| Lu, L; Shohag, MJ; Tian, S; Yang, X; Zhang, J; Zhang, M | 1 |
| Freisinger, E; Tarasava, K | 1 |
| Duncan, KE; Gullons, M; Irvine, GW; Stillman, MJ | 1 |
| De Boeck, G; Hattink, J; Hoogenboom, RL; Kan, KA; Traag, WA; van Eijkeren, JC; van Oostrom, S; van Polanen, A; Verbunt, JT; Zeilmaker, MJ | 1 |
| Carotenuto, R; Scudiero, R; Tussellino, M | 1 |
| Terzi, H; Yıldız, M | 1 |
| Pinter, TB; Stillman, MJ | 1 |
| Barbare, JC; Barget, N; Bodeau, S; Chauffert, B; Coriat, R; François, C; Galmiche, A; Ganne, N; Godin, C; Gutierrez, L; Houessinon, A; Louandre, C; Mongelard, G; Régimbeau, JM; Saidak, Z; Sauzay, C; Takahashi, S | 1 |
| Alam, MF; Ghosal, A; Kabir, AH; Rahman, MF | 1 |
| Malekzadeh, R; Shahpiri, A | 1 |
| Ding, G; Gong, JM; Meng, S; Peng, JS; Yi, HY | 1 |
| Irvine, GW; Santolini, M; Stillman, MJ | 1 |
| Irvine, GW; Stillman, MJ | 1 |
| Heinlein, L; Irvine, GW; Renaud, JB; Stillman, MJ; Sumarah, MW | 1 |
| Wang, W; Xu, J; Zhou, H | 1 |
| Albalat, R; Artime, S; Calatayud, S; Cañestro, C; Espinosa-Sánchez, L; Garcia-Risco, M; Palacios, Ò; Rojas, NS | 1 |
| Chaudhuri, G; Janzen, C; Kawahara, B; Mascharak, PK; Ramadoss, S; Sen, S | 1 |
| Ansari, MA; Behera, SK; Dubey, AK; Gautam, A; Kumar, A; Kumar, N; Mallick, S; Pande, V; Pandey, V; Ranjan, R; Sahu, N; Sanyal, I | 1 |
| DeNicola, GM; Ward, NP | 1 |
| Rahimi, AM; Shahpiri, A | 1 |
| Chesnov, S; Freisinger, E; Habjanič, J; Zerbe, O | 1 |
| Kozłowski, H; Krzywoszyńska, K; Ostrowska, M; Potocki, S; Swiątek-Kozłowska, J | 1 |
| Hudson, E; Korkola, NC; Stillman, MJ | 1 |
| Bulathge, AW; Gassensmith, JJ; Herbert, FC; Meloni, G; Villones, RLE | 1 |
| Gao, X; Lin, J; Lin, X; Lu, L; Tian, S; Xie, R; Xu, L; Zhao, J | 1 |
| Li, J; Li, M; Liu, B; Pan, Y; Qin, Y; Zhang, X; Zheng, Y | 1 |
| Black, T; Minghetti, M; Oldham, D; Stewart, TJ | 1 |
| Chakrabarty, D; Dutta, P; Gautam, N; Kidwai, M; Tiwari, M | 1 |
11 review(s) available for cysteine and metallothionein
| Article | Year |
|---|---|
Metallothionein: an exceptional metal thiolate protein.
Topics: Amino Acid Sequence; Animals; Cysteine; Digestive System; Humans; Kidney; Liver; Metalloproteins; Metallothionein; Neurospora crassa | 1979 |
Non-metallothionein cadmium binding proteins.
Topics: Amino Acids; Animals; Carbohydrates; Cysteine; Horses; Metallothionein; Molecular Weight; Mollusca | 1985 |
The production of transgenic domestic livestock: successes, failures and the need for nuclear transfer.
Topics: Animals; Animals, Domestic; Animals, Genetically Modified; Body Weight; Cell Nucleus; Cysteine; Female; Gene Transfer Techniques; Growth Hormone; Male; Metallothionein; Nuclear Transfer Techniques; Organ Size; Sheep | 1998 |
Antioxidant role of metallothioneins: a comparative overview.
Topics: Animals; Antioxidants; Cell Line; Copper; Cricetinae; Cysteine; Fishes; Hydrogen Peroxide; Iron; Metallothionein; Mice; Mollusca; Nitric Oxide; Oxidative Stress; Rats; Saccharomyces cerevisiae; Zinc | 2000 |
Thiols in cellular redox signalling and control.
Topics: Albumins; Animals; Apoptosis; Cysteine; Disulfides; Glutathione; Glutathione Peroxidase; Humans; Metallothionein; Necrosis; Oxidation-Reduction; Oxidative Stress; Signal Transduction; Sulfhydryl Compounds; Transcription Factors | 2001 |
Oxidation of zinc-binding cysteine residues in transcription factor proteins.
Topics: Amino Acid Sequence; Antioxidants; Binding Sites; Cobalt; Cysteine; Gene Expression Regulation; Hydrogen Peroxide; Iron; Metalloproteins; Metallothionein; Models, Molecular; Molecular Sequence Data; Nickel; Oxidants; Oxidation-Reduction; Oxygen; Protein Conformation; Structure-Activity Relationship; Sulfhydryl Reagents; Transcription Factors; Zinc; Zinc Fingers | 2001 |
The zinc/thiolate redox biochemistry of metallothionein and the control of zinc ion fluctuations in cell signaling.
Topics: Cations, Divalent; Cysteine; Metalloproteins; Metallothionein; Oxidation-Reduction; Signal Transduction; Zinc | 2007 |
Plant metallothioneins--metal chelators with ROS scavenging activity?
Topics: Chelating Agents; Cysteine; Gene Expression Regulation, Plant; Metallothionein; Metals; Models, Molecular; Plant Proteins; Promoter Regions, Genetic; Protein Isoforms; Reactive Oxygen Species | 2011 |
Structural features specific to plant metallothioneins.
Topics: Amino Acid Sequence; Animals; Cysteine; Humans; Metallothionein; Metals; Molecular Sequence Data; Plant Proteins; Protein Structure, Secondary; Species Specificity | 2011 |
Residue Modification and Mass Spectrometry for the Investigation of Structural and Metalation Properties of Metallothionein and Cysteine-Rich Proteins.
Topics: Animals; Carrier Proteins; Cysteine; Humans; Kinetics; LIM Domain Proteins; Metallothionein; Metals; Molecular Dynamics Simulation; Recombinant Proteins; Spectrometry, Mass, Electrospray Ionization | 2017 |
Sulfur metabolism and its contribution to malignancy.
Topics: Animals; Carcinogenesis; Chelating Agents; Cysteine; Humans; Metallothionein; Methionine; Mitogen-Activated Protein Kinase Kinases; Neoplasms; Oxidation-Reduction; Oxidative Stress; Sulfhydryl Compounds; Sulfur | 2019 |
216 other study(ies) available for cysteine and metallothionein
| Article | Year |
|---|---|
Circular dichroism of metallothioneins. A structural approach.
Topics: Cadmium; Circular Dichroism; Copper; Cysteine; Hydrogen-Ion Concentration; Metalloproteins; Metallothionein; Models, Molecular; Protein Conformation; Zinc | 1978 |
Metal-binding and detoxification effect of synthetic oligopeptides containing three cysteinyl residues.
Topics: Cations, Divalent; Cells, Cultured; Cysteine; Metalloproteins; Metallothionein; Metals; Oligopeptides; Structure-Activity Relationship | 1979 |
Inducible gold-binding proteins in rat kidneys.
Topics: Animals; Carrier Proteins; Copper; Cysteine; Female; Gold; In Vitro Techniques; Kidney; Metalloproteins; Metallothionein; Protein Binding; Rats; Subcellular Fractions | 1979 |
Induction of cadmium-thionein in isolated rat liver cells.
Topics: Animals; Cadmium; Chromatography, Liquid; Cycloheximide; Cysteine; Dactinomycin; In Vitro Techniques; Liver; Male; Metalloproteins; Metallothionein; Rats | 1978 |
Turnover of metallothioneins in rat liver.
Topics: Amino Acids; Animals; Cadmium; Chemical Phenomena; Chemistry; Cysteine; Electrophoresis, Polyacrylamide Gel; Female; Half-Life; Kinetics; Liver; Metalloproteins; Metallothionein; Rats; Zinc | 1978 |
Induction of renal metallothionein synthesis by parenteral cadmium-thionein in rats.
Topics: Animals; Cadmium; Cysteine; Kidney; Liver; Male; Metalloproteins; Metallothionein; Rats; Subcellular Fractions; Time Factors | 1978 |
113Cd nuclear magnetic resonance of metallothionein: non-equivalent CdS4 sites.
Topics: Binding Sites; Cadmium; Cysteine; Ligands; Liver; Magnetic Resonance Spectroscopy; Metalloproteins; Metallothionein; Zinc | 1978 |
Effect of zinc status of rats on the synthesis and degradation of copper-induced metallothioneins.
Topics: Animals; Chromatography, Gel; Copper; Cysteine; Cytosol; Half-Life; Kidney; Leucine; Liver; Male; Metalloproteins; Metallothionein; Rats; Zinc | 1978 |
Letter: Suppressive effect of zinc on the toxicity of mercury.
Topics: Animals; Cysteine; Liver; Male; Mercury Poisoning; Metallothionein; Rats; Zinc | 1976 |
Amino-acid sequence of equine renal metallothionein-1B.
Topics: Amino Acid Sequence; Animals; Binding Sites; Cysteine; Horses; Kidney; Metalloproteins; Metallothionein | 1976 |
Biological function of metallothionein. I. Synthesis and degradation of rat liver metallothionein.
Topics: Animals; Cadmium; Chromatography, Gel; Copper; Cysteine; Dose-Response Relationship, Drug; Liver; Male; Mercury; Metallothionein; Rats; Time Factors; Zinc | 1975 |
Isolation and characterization of a hepatic metallothionein from mice.
Topics: Amino Acids; Animals; Cadmium; Chromatography, Gel; Cysteine; Isoelectric Focusing; Liver; Male; Metalloproteins; Metallothionein; Mice; Mice, Inbred CBA; Ultracentrifugation; Zinc | 1975 |
Uptake of cadmium is diminished in transfected mouse NIH/3T3 cells enriched for metallothionein.
Topics: 3T3 Cells; Animals; Biological Transport; Bovine papillomavirus 1; Cadmium; Carrier Proteins; Cell Survival; Chromosome Deletion; Cysteine; Endoplasmic Reticulum Chaperone BiP; Genetic Vectors; Heat-Shock Proteins; Metallothionein; Mice; Molecular Chaperones; Phenotype; Plasmids; Promoter Regions, Genetic; Restriction Mapping; Transfection | 1992 |
Isolation and characterization of a Cd-binding protein from Allolobophora caliginosa (Annelida, Oligochaeta): distinction from metallothioneins.
Topics: Amino Acids; Animals; Chromatography, Gel; Chromatography, Ion Exchange; Cysteine; Electrophoresis, Polyacrylamide Gel; Isoelectric Focusing; Metallothionein; Molecular Weight; Oligochaeta | 1992 |
Comparison of the NMR solution structure and the x-ray crystal structure of rat metallothionein-2.
Topics: Amino Acid Sequence; Animals; Binding Sites; Cadmium; Cysteine; Magnetic Resonance Spectroscopy; Metallothionein; Models, Molecular; Protein Conformation; Rats; X-Ray Diffraction; Zinc | 1992 |
Metallothioneins of monocytes and lymphocytes.
Topics: Adult; Autoradiography; B-Lymphocytes; Burkitt Lymphoma; Cadmium; Cadmium Chloride; Cadmium Radioisotopes; Cell Line; Cell Line, Transformed; Cell Separation; Chromatography, Gel; Cysteine; Electrophoresis, Polyacrylamide Gel; Erythrocytes; Flow Cytometry; Granulocytes; Herpesvirus 4, Human; Humans; In Vitro Techniques; Leukemia; Lymphocytes; Metallothionein; Monocytes; Sulfur Radioisotopes; T-Lymphocytes | 1991 |
Mutation of invariant cysteines of mammalian metallothionein alters metal binding capacity, cadmium resistance, and 113Cd NMR spectrum.
Topics: Animals; Base Sequence; Cadmium; Cloning, Molecular; Cricetinae; Cricetulus; Cysteine; Electrophoresis, Polyacrylamide Gel; Isotopes; Magnetic Resonance Spectroscopy; Metallothionein; Metals; Molecular Sequence Data; Mutation; Plasmids; Saccharomyces cerevisiae | 1991 |
Detection of carboxymethylmetallothionein by sodium dodecyl sulfate-polyacrylamide gel electrophoresis.
Topics: Animals; Autoradiography; Cells, Cultured; Cysteine; Cytosol; Dithiothreitol; Electrophoresis, Polyacrylamide Gel; Indicators and Reagents; Iodoacetates; Iodoacetic Acid; Liver; Metallothionein; Sodium Dodecyl Sulfate; Sulfur Radioisotopes | 1991 |
Cysteine modification of metallothionein.
Topics: Apoproteins; Benzenesulfonates; Cysteine; Indicators and Reagents; Metallothionein; Methylation | 1991 |
Determination of the three-dimensional structure of metallothioneins by nuclear magnetic resonance spectroscopy in solution.
Topics: Animals; Binding Sites; Cadmium; Cadmium Chloride; Cysteine; Hydrogen; Isotopes; Liver; Magnetic Resonance Spectroscopy; Male; Metallothionein; Models, Molecular; Protein Conformation; Rats; Rats, Inbred Strains; Software; Solutions | 1991 |
Metalloselenonein, the selenium analogue of metallothionein: synthesis and characterization of its complex with copper ions.
Topics: Amino Acids; Chromatography, High Pressure Liquid; Circular Dichroism; Copper; Cysteine; Metallothionein; Neurospora crassa; Selenium; Selenocysteine; Spectrometry, Fluorescence; Spectrum Analysis; Structure-Activity Relationship | 1991 |
Amino acid analysis of metallothionein.
Topics: Amino Acids; Animals; Autoanalysis; Cysteine; Hydrolysis; Indicators and Reagents; Mammals; Metallothionein; Neurospora crassa; Oxidation-Reduction; Tyrosine | 1991 |
Choroid plexus protects cerebrospinal fluid against toxic metals.
Topics: Animals; Arsenic; Blood Chemical Analysis; Cadmium; Cerebral Cortex; Cerebrospinal Fluid; Choroid Plexus; Cysteine; Dose-Response Relationship, Drug; Glutathione; Lead; Mercury; Metallothionein; Ouabain; Rats; Rats, Inbred Strains; Sodium-Potassium-Exchanging ATPase; Sulfhydryl Compounds | 1991 |
Refined crystal structure of Cd, Zn metallothionein at 2.0 A resolution.
Topics: Amino Acid Sequence; Animals; Cadmium; Crystallization; Cysteine; Hydrogen Bonding; Liver; Macromolecular Substances; Metallothionein; Models, Molecular; Molecular Sequence Data; Protein Conformation; Rats; Sulfur; Tungsten; X-Ray Diffraction; Zinc | 1991 |
Amino acid sequence of cadmium-binding peptide induced in a marine diatom, Phaeodactylum tricornutum.
Topics: Amino Acid Sequence; Cadmium; Cysteine; Dansyl Compounds; Eukaryota; Glutamates; Glutamic Acid; Glutathione; Glycine; Metallothionein; Molecular Sequence Data; Phytoplankton | 1990 |
Zinc-induced metallothionein synthesis by Caco-2 cells.
Topics: Animals; Cell Line; Cycloheximide; Cysteine; Dactinomycin; Intestinal Absorption; Intestinal Mucosa; Intestines; Metallothionein; Zinc | 1991 |
Effect of cysteine replacements at positions 13 and 50 on metallothionein structure.
Topics: Animals; Cadmium; Circular Dichroism; Cricetinae; Cricetulus; Cysteine; Dithionitrobenzoic Acid; Hydrogen-Ion Concentration; Kinetics; Metallothionein; Mutagenesis, Site-Directed; Protein Binding; Protein Conformation; Recombinant Proteins; Saccharomyces cerevisiae; Spectrophotometry, Ultraviolet | 1991 |
A modified technique for the measurement of sulfhydryl groups oxidized by reactive oxygen intermediates.
Topics: Catalase; Cysteine; Dithionitrobenzoic Acid; Free Radicals; Hydrogen Peroxide; Hypoxanthine; Hypoxanthines; Metallothionein; Nitrophenols; Oxygen; Sulfhydryl Compounds; Xanthine Oxidase | 1990 |
Metallothionein genes from the flowering plant Mimulus guttatus.
Topics: Cloning, Molecular; Copper; Cysteine; DNA; DNA Transposable Elements; Gene Expression Regulation; Metallothionein; Molecular Sequence Data; Plants; RNA, Messenger; Sequence Homology, Nucleic Acid | 1990 |
On the metallothionein, glutathione and cysteine relationship in rat liver.
Topics: Animals; Body Weight; Buthionine Sulfoximine; Cysteine; Glutathione; Isoxazoles; Liver; Male; Metallothionein; Methionine Sulfoximine; Organ Size; Rats; Rats, Inbred Strains; Starvation; Stress, Physiological; Zinc | 1990 |
Quantitation of Cu-containing metallothionein by a Cd-saturation method.
Topics: Animals; Cadmium; Cadmium Radioisotopes; Cells, Cultured; Chemistry Techniques, Analytical; Child; Child, Preschool; Chromatography, Gel; Copper; Cysteine; Ethanolamines; Fibroblasts; Glutathione; Hepatolenticular Degeneration; Humans; Male; Metallothionein; Molybdenum; Rats; Rats, Inbred Strains | 1990 |
Effect of sulfhydryl-deficient diets on hepatic metallothionein, glutathione, and adenosine 3'-phosphate 5'-phosphosulfate (PAPS) levels in rats.
Topics: Adenine Nucleotides; Animals; Chlorides; Cysteine; Cystine; Diet; Glutathione; Liver; Male; Metallothionein; Methionine; Phosphoadenosine Phosphosulfate; Rats; Rats, Inbred Strains; Zinc; Zinc Compounds | 1990 |
Characterization of metallothionein cDNAs induced by cadmium in the nematode Caenorhabditis elegans.
Topics: Amino Acid Sequence; Animals; Base Sequence; Cadmium; Caenorhabditis; Cloning, Molecular; Cysteine; DNA; Humans; Metallothionein; Molecular Sequence Data; Sequence Homology, Nucleic Acid | 1990 |
Rates of metallothionein synthesis, degradation and accretion in a chicken macrophage cell line.
Topics: Animals; Cell Line, Transformed; Chelating Agents; Chickens; Chromatography, High Pressure Liquid; Cysteine; Macrophages; Metallothionein; Regression Analysis; Zinc | 1990 |
Involvement of sulfhydryl metabolism in tolerance to cadmium in testicular cells.
Topics: Animals; Cadmium; Chromatography, Gel; Cysteine; Cytosol; Drug Administration Schedule; Drug Tolerance; Electrophoresis, Polyacrylamide Gel; Glutathione; Liver; Male; Metallothionein; Rats; Rats, Inbred Strains; Sulfhydryl Compounds; Testis; Time Factors | 1990 |
Metallothionein protein variants generated in rat liver as a result of DNA and RNA ethylations by the carcinogen diethylnitrosamine.
Topics: Alkylation; Animals; Cysteine; Diethylnitrosamine; DNA; Genetic Variation; Liver; Male; Metallothionein; Phenylalanine; Rats; Rats, Inbred Strains; RNA; Tyrosine | 1986 |
The nature of thiol-compounds which trap cuprous ion reductively liberated from bleomycin-Cu(II) in cells.
Topics: Alcohol Oxidoreductases; Animals; Bleomycin; Chromatography, High Pressure Liquid; Copper; Cysteine; Dithiothreitol; Female; Liver; Metallothionein; Rats; Sulfhydryl Compounds; Zinc | 1987 |
Gold sodium thiomalate toxicity in cadmium-sensitive and cadmium-resistant Chinese hamster ovary cells.
Topics: Animals; Cadmium; Cell Division; Cell Line; Chlorides; Chromatography; Contraceptives, Oral, Combined; Cricetinae; Cysteine; Drug Resistance; Female; Gold Sodium Thiomalate; Mesocricetus; Metallothionein; Ovary; Zinc; Zinc Compounds | 1989 |
Amino acids and peptides. XXIV. Synthesis of Neurospora crassa metallothionein and related cysteine-containing peptides and examination of their heavy metal-binding properties.
Topics: Amino Acid Sequence; Cysteine; Metallothionein; Metals; Molecular Sequence Data; Neurospora; Neurospora crassa; Peptides; Protein Binding | 1989 |
Resistance of cultured hepatoma cells to copper toxicity. Purification and characterization of the hepatoma metallothionein.
Topics: Amino Acids; Animals; Carcinoma, Hepatocellular; Cell Line; Copper; Cysteine; Drug Resistance; Liver Neoplasms; Metallothionein; Molecular Weight; Neoplasm Proteins; Rats; Tumor Cells, Cultured | 1989 |
Metabolic changes in glutathione and metallothionein in newborn rat liver.
Topics: Alkynes; Animals; Animals, Newborn; Buthionine Sulfoximine; Cysteine; Female; gamma-Glutamyltransferase; Glutathione; Glycine; Liver; Metallothionein; Methionine Sulfoximine; Pargyline; Pregnancy; Rats; Zinc | 1989 |
A cysteine-rich nuclear protein activates yeast metallothionein gene transcription.
Topics: Amino Acid Sequence; Base Sequence; Cloning, Molecular; Cysteine; DNA-Binding Proteins; DNA, Fungal; Fungal Proteins; Genes, Fungal; Genetic Complementation Test; Metallothionein; Molecular Sequence Data; Mutation; Nuclear Proteins; Recombinant Fusion Proteins; RNA, Messenger; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Transcription Factors; Transcription, Genetic | 1989 |
The amino acid composition of the zinc-induced metallothionein isoforms in rat brain.
Topics: Amino Acids; Animals; Chromatography, High Pressure Liquid; Cysteine; Male; Metallothionein; Rats; Rats, Inbred Strains; Stereoisomerism; Zinc | 1989 |
Uptake of cadmium and metallothionein by rat everted intestinal sacs.
Topics: Animals; Cadmium; Cysteine; In Vitro Techniques; Intestinal Absorption; Male; Metallothionein; Protein Binding; Rats; Rats, Inbred Strains | 1989 |
Subcellular toxicity of low level cadmium in rats: effect on cytochrome c oxidase.
Topics: Animals; Cadmium; Cysteine; Electron Transport Complex IV; Iron; Male; Maleates; Metallothionein; Mitochondria; Rats; Rats, Inbred Strains | 1988 |
Metallothionein in the liver of the small lizard Podarcis muralis.
Topics: Amino Acids; Animals; Cadmium; Chromatography, Gel; Copper; Cysteine; In Vitro Techniques; Liver; Lizards; Metallothionein; Molecular Weight; Quail; Rats; Species Specificity; Spectrophotometry, Ultraviolet; Turtles; Zinc | 1986 |
Crystal structure of Cd,Zn metallothionein.
Topics: Animals; Cadmium; Chemical Phenomena; Chemistry; Crystallization; Cysteine; Metallothionein; Protein Conformation; Rats; X-Ray Diffraction; Zinc | 1987 |
Spatial structure of rabbit liver metallothionein-2 in solution by NMR.
Topics: Amino Acid Sequence; Animals; Cysteine; Liver; Magnetic Resonance Spectroscopy; Metallothionein; Molecular Sequence Data; Rabbits; Solutions; X-Ray Diffraction | 1987 |
NMR analysis of the structure and metal sequestering properties of metallothioneins.
Topics: Amino Acid Sequence; Animals; Brachyura; Cadmium; Copper; Cysteine; Humans; Liver; Magnetic Resonance Spectroscopy; Metallothionein; Metals; Molecular Sequence Data; Neurospora crassa; Protein Conformation; Rabbits; Saccharomyces cerevisiae; Zinc | 1987 |
Structural and functional aspects of metal-thiolate centres in metallothionein.
Topics: Animals; Binding Sites; Cobalt; Copper; Cysteine; Magnetic Resonance Spectroscopy; Metallothionein; Metals; Neurospora crassa; Saccharomyces cerevisiae; Spectrophotometry; Swine; Zinc | 1987 |
Cadmium binding and metal cluster formation in metallothionein: a differential modification study.
Topics: Animals; Binding Sites; Cadmium; Chemical Phenomena; Chemistry; Cysteine; Iodoacetamide; Metallothionein; Peptide Fragments; Trypsin | 1987 |
Human hepatic metallothioneins: resolution of six isoforms.
Topics: Amino Acids; Chromatography, High Pressure Liquid; Chromatography, Ion Exchange; Cysteine; Gene Expression Regulation; Humans; Hydrogen-Ion Concentration; Liver; Metallothionein | 1987 |
Cadmium-binding proteins in rat testes: characterization and apparent source of the low-molecular-weight protein.
Topics: Amino Acids; Animals; Cadmium; Chromatography, Gel; Chromatography, Ion Exchange; Cysteine; Electrophoresis, Polyacrylamide Gel; Liver; Male; Metallothionein; Molecular Weight; Rats; Spectrophotometry, Ultraviolet; Testis | 1987 |
Purification and characterization of atypical cadmium-binding polypeptides from Zea mays.
Topics: Amino Acids; Cadmium; Chromatography, Gel; Chromatography, High Pressure Liquid; Cysteine; Disulfides; Macromolecular Substances; Metallothionein; Molecular Weight; Plants; Zea mays | 1987 |
Effects of heavy metals on Drosophila larvae and a metallothionein cDNA.
Topics: Amino Acid Sequence; Animals; Cadmium; Cloning, Molecular; Copper; Cysteine; DNA; Drosophila melanogaster; Gene Expression Regulation; Larva; Lysosomes; Metallothionein; Silver; Zinc | 1986 |
Effects of low-level cadmium in rats: influence of pretreatment with thiol-modulating agents.
Topics: Animals; Cadmium; Cysteine; Enteral Nutrition; Glutathione Reductase; Kidney; Liver; Male; Maleates; Metallothionein; Organ Size; Osmolar Concentration; Rats; Rats, Inbred Strains; Sulfhydryl Compounds | 1988 |
Conformation of [Cd7]-metallothionein-2 from rat liver in aqueous solution determined by nuclear magnetic resonance spectroscopy.
Topics: Animals; Cadmium; Cysteine; Liver; Magnetic Resonance Spectroscopy; Mathematical Computing; Metallothionein; Models, Molecular; Protein Conformation; Rabbits; Rats; Solutions; X-Ray Diffraction | 1988 |
Kinetic lability of zinc bound to metallothionein in Ehrlich cells.
Topics: Animals; Cadmium; Carcinoma, Ehrlich Tumor; Chelating Agents; Chromatography, Gel; Cysteine; Kinetics; Metallothionein; Models, Biological; Resins, Synthetic; Sulfur Radioisotopes; Trichloroacetic Acid; Tumor Cells, Cultured; Zinc | 1988 |
Effect of mutation of cysteinyl residues in yeast Cu-metallothionein.
Topics: Carrier Proteins; Copper; Cysteine; Genes; Genes, Fungal; Hydrogen-Ion Concentration; Kinetics; Metallothionein; Mutation; Saccharomyces cerevisiae | 1988 |
DNA radiation damage and its modification by metallothionein.
Topics: Animals; Cell Line; Cell Survival; Cysteine; Deoxyadenine Nucleotides; DNA; DNA Damage; Metallothionein; Oxygen; Radiation-Protective Agents | 1987 |
Protective role of renal metallothionein against Cd nephropathy in rats.
Topics: Animals; Cadmium; Chromates; Cysteine; Kidney; Liver; Male; Metallothionein; Peptide Fragments; Rats; Rats, Inbred Strains; Sodium Compounds; Subcellular Fractions; Time Factors | 1987 |
Sequence-specific 1H-NMR assignments in rat-liver metallothionein-2.
Topics: Amino Acid Sequence; Animals; Cysteine; Liver; Magnetic Resonance Spectroscopy; Metallothionein; Rats | 1987 |
Dynamic metal-thiolate cluster structure of metallothioneins.
Topics: Animals; Cadmium; Cysteine; Gamma Rays; Liver; Magnetic Resonance Spectroscopy; Metallothionein; Rabbits; X-Rays; Zinc | 1986 |
Purification and characterization studies of cadmium-binding proteins from the American oyster, Crassostrea virginica.
Topics: Amino Acids; Animals; Cadmium; Chromatography, Gel; Copper; Cysteine; Cytosol; Electrophoresis, Polyacrylamide Gel; Metallothionein; Ostreidae; Seasons; Spectrophotometry, Ultraviolet; Zinc | 1986 |
Effect of pretreatment with cadmium/cysteine or metallothionein on accumulation of cadmium challenged with either complexes.
Topics: Animals; Biological Transport, Active; Cadmium; Cysteine; Drug Tolerance; Female; Kidney; Liver; Metallothionein; Rats; Rats, Inbred Strains; Tissue Distribution | 1986 |
Uptake of cadmium in isolated kidney cells--influence of binding form and in vivo pretreatment.
Topics: Albumins; Animals; Cadmium; Cysteine; In Vitro Techniques; Kidney; Male; Metallothionein; Rats; Rats, Inbred Strains | 1986 |
Utilization of methionine as a sulfhydryl source for metallothionein synthesis in rat primary hepatocyte cultures.
Topics: Animals; Chlorides; Cysteine; Glutathione; Liver; Male; Metallothionein; Methionine; Rats; Rats, Inbred Strains; Sulfates; Time Factors; Zinc; Zinc Compounds | 1987 |
Crystal structure of Cd,Zn metallothionein.
Topics: Animals; Binding Sites; Cadmium; Crystallography; Cysteine; Metallothionein; Models, Molecular; Protein Conformation; Rats; Solutions; X-Ray Diffraction; Zinc | 1986 |
Effects of acetaminophen on cadmium metabolism in mice.
Topics: Acetaminophen; Animals; Body Burden; Cadmium; Chromatography, Gel; Cysteine; Feces; Kidney; Liver; Male; Metallothionein; Mice; Phenobarbital | 1986 |
Studies on the metabolism of rat liver copper-metallothionein.
Topics: Animals; Chromatography, Gel; Copper; Cysteine; Half-Life; In Vitro Techniques; Liver; Male; Metallothionein; Rats; Rats, Inbred Strains; Subcellular Fractions | 1985 |
The interaction of zinc and cadmium in the synthesis of hepatic metallothionein in rats.
Topics: Animals; Cadmium; Cysteine; Drug Interactions; Liver; Male; Metallothionein; Rats; Rats, Inbred Strains; Sulfur Radioisotopes; Zinc | 1985 |
Cadmium found in non-soluble fraction of kidney homogenates and its relation to renal dysfunction after cadmium-cysteine administration.
Topics: Animals; Cadmium; Chromatography, High Pressure Liquid; Creatinine; Cysteine; Glucose; Injections, Intravenous; Kidney; Kidney Diseases; Liver; Male; Metallothionein; Mice; Mice, Inbred ICR; Proteins; Tissue Distribution | 1985 |
Role of sulfhydryls in the hepatotoxicity of organic and metallic compounds.
Topics: Acetaminophen; Animals; Biotransformation; Bromobenzenes; Cadmium Poisoning; Chemical and Drug Induced Liver Injury; Cysteine; Cytochrome P-450 Enzyme System; Humans; Metallothionein; Metals; Microsomes, Liver; Sulfhydryl Compounds; Zinc | 1985 |
Translatability of rat kidney mRNA after mercury administration.
Topics: Animals; Cysteine; Isoelectric Focusing; Kidney; Leucine; Male; Mercury; Metallothionein; Molecular Weight; Polyribosomes; Protein Biosynthesis; Rats; Rats, Inbred Strains; RNA, Messenger | 1985 |
113CD-1H spin-spin couplings in homonuclear 1H correlated spectroscopy of metallothionein. Identification of the cysteine 1H spin systems.
Topics: Animals; Cadmium; Chemical Phenomena; Chemistry; Cysteine; Isotopes; Liver; Magnetic Resonance Spectroscopy; Metallothionein; Protons; Rabbits; Spectrum Analysis | 1984 |
Effect of molybdenum on the acute toxicity of mercuric chloride. IV. Effect of molybdenum on mercury-mediated metallothionein mRNA induction.
Topics: Animals; Cell-Free System; Chlorides; Cysteine; Drug Interactions; Kidney; Male; Mercuric Chloride; Mercury; Metallothionein; Mitochondria; Molybdenum; Rats; Rats, Inbred Strains; RNA, Messenger; Triticum | 1984 |
Structure of mammalian metallothionein.
Topics: Amino Acid Sequence; Animals; Cobalt; Cysteine; Electron Spin Resonance Spectroscopy; Humans; Magnetic Resonance Spectroscopy; Metallothionein; Spectrophotometry, Infrared | 1984 |
Inducibility of metallothionein throughout the cell cycle.
Topics: Animals; Cell Cycle; Chlorides; Cricetinae; Cricetulus; Cysteine; Metallothionein; Zinc; Zinc Compounds | 1984 |
Protein mapping of two metallothionein-rich cell strains and their parent lines, using high-resolution two-dimensional electrophoresis.
Topics: Animals; Autoradiography; Cadmium; Cell Line; Chromatography, Gel; Cysteine; Drug Resistance; Electrophoresis, Polyacrylamide Gel; Epithelium; Fibroblasts; Humans; Metallothionein; Mice; Mutation | 1984 |
Amino acids and peptides. IX. Synthesis of cysteine-containing peptide fragments related to human hepatic metallothionein II (hMT II) and determination of their heavy metal-binding properties.
Topics: Cysteine; Humans; Liver; Metallothionein; Metals; Peptide Fragments; Protein Binding | 1983 |
Metallothionein and the development of the mottled disorder in the mouse.
Topics: Animals; Copper; Cysteine; Female; Kidney; Liver; Metallothionein; Mice; Mice, Mutant Strains; Pigmentation Disorders | 1983 |
A study of intestinal copper-binding proteins in mottled mice.
Topics: Aging; Animals; Brain Diseases, Metabolic; Carrier Proteins; Copper; Cysteine; Humans; Intestinal Mucosa; Male; Menkes Kinky Hair Syndrome; Metalloproteins; Metallothionein; Mice; Mice, Mutant Strains; Models, Biological; Zinc | 1983 |
Dietary protein effects on cadmium and metallothionein accumulation in the liver and kidney of rats.
Topics: Animals; Body Weight; Cadmium; Catechol O-Methyltransferase; Cysteine; Dietary Proteins; Kidney; Liver; Male; Metallothionein; Rats; Rats, Inbred Strains | 1984 |
Copper induction of translatable metallothionein messenger RNA.
Topics: Animals; Copper; Cysteine; Electrophoresis, Polyacrylamide Gel; Leucine; Liver; Male; Metalloproteins; Metallothionein; Protein Biosynthesis; Rats; Rats, Inbred Strains; RNA, Messenger; Serine; Sulfates; Zinc; Zinc Sulfate | 1981 |
Relation between metal and glutathione concentrations in mouse liver after cadmium, zinc or copper loading.
Topics: Animals; Cadmium; Copper; Cysteine; Glutathione; Liver; Male; Metallothionein; Metals; Mice; Mice, Inbred ICR; Zinc | 1983 |
Cd2+ responses of cultured human blood cells.
Topics: Adult; Cadmium; Cell Survival; Cells, Cultured; Cysteine; Granulocytes; Humans; Leukocytes; Lymphocytes; Metallothionein; Monocytes | 1983 |
Sulfur amino acids and the liver. Introduction.
Topics: Amino Acids, Sulfur; Animals; Bile Acids and Salts; Cysteine; Glutathione; Liver; Metallothionein; Methionine; Oxidation-Reduction; Taurine | 1983 |
Uptake and binding of cadmium and mercury to metallothionein in rat hepatocyte primary cultures.
Topics: Animals; Cadmium; Cells, Cultured; Cysteine; Liver; Mercury; Metalloproteins; Metallothionein; Protein Binding; Proteins; Rats; Rats, Inbred Strains; Time Factors | 1982 |
Degradation of 35S-labeled metallothionein in the liver and the kidney of brindled mice: model for Menkes' disease.
Topics: Amino Acids; Animals; Brain Diseases, Metabolic; Cysteine; Disease Models, Animal; Half-Life; Humans; Kidney; Liver; Menkes Kinky Hair Syndrome; Metalloproteins; Metallothionein; Mice; Mice, Inbred Strains | 1981 |
Ovine and bovine metallothioneins: purification, number of species, zinc content and amino acid composition.
Topics: Amino Acids; Animals; Cattle; Cysteine; Diet; Female; Kidney; Liver; Male; Metalloproteins; Metallothionein; Pancreas; Sheep; Zinc | 1981 |
Effects of methylmercury on zinc-thionein levels of rat liver.
Topics: Animals; Cysteine; Cytosol; Kidney; Liver; Male; Metalloproteins; Metallothionein; Methylmercury Compounds; Rats; Zinc | 1981 |
Metal-binding proteins in bovine and porcine hepatic and renal tissues: isolation and characterization.
Topics: Amino Acids; Animals; Cadmium; Cattle; Cysteine; Histidine; Kidney; Liver; Metalloproteins; Metallothionein; Molecular Weight; Swine; Zinc | 1980 |
The influence of nutritional deficiencies on gastrointestinal uptake of cadmium and cadmium-metallothionein in rats.
Topics: Animals; Cadmium; Cysteine; Intestinal Absorption; Iron Deficiencies; Male; Metallothionein; Rats; Rats, Sprague-Dawley; Zinc | 1995 |
Comparative cytotoxicity of exogenous cadmium-metallothionein and cadmium ion in cultured vascular endothelial cells.
Topics: Adenine; Animals; Aorta; Binding, Competitive; Cadmium; Cadmium Chloride; Cattle; Cells, Cultured; Chlorides; Cysteine; Endothelium, Vascular; Glutathione; Metallothionein; Rabbits; Tritium | 1995 |
Purification and primary structure of metallothioneins induced by cadmium in the protists Tetrahymena pigmentosa and Tetrahymena pyriformis.
Topics: Amino Acid Sequence; Animals; Cadmium; Chromatography; Cysteine; Endopeptidases; Mass Spectrometry; Metallothionein; Molecular Sequence Data; Molecular Weight; Peptide Fragments; Sequence Alignment; Sequence Analysis; Spectrophotometry, Ultraviolet; Tetrahymena; Tetrahymena pyriformis | 1994 |
Covalent sequestration of melphalan by metallothionein and selective alkylation of cysteines.
Topics: Alkylation; Amino Acid Sequence; Animals; Binding Sites; Cysteine; Drug Resistance; Hydrogen-Ion Concentration; In Vitro Techniques; Liver; Melphalan; Metallothionein; Molecular Sequence Data; Molecular Structure; Peptide Fragments; Rabbits; Spectrometry, Mass, Fast Atom Bombardment | 1995 |
Modulation of resistance to anticancer drugs by inhibition of metallothionein synthesis.
Topics: Alkynes; Animals; Cisplatin; Colonic Neoplasms; Cysteine; Doxorubicin; Drug Resistance; Female; Fibrosarcoma; Glycine; Humans; Male; Melphalan; Metallothionein; Mice; Mice, Inbred BALB C; Mice, Inbred ICR; Mice, Nude; Pargyline; Sulfates; Tumor Cells, Cultured; Urinary Bladder Neoplasms; Zinc Compounds; Zinc Sulfate | 1994 |
Mössbauer and magnetic susceptibility studies on iron(II) metallothionein from rabbit liver. Evidence for the existence of an unusual type of [M3(CysS)9]3- cluster.
Topics: Adamantane; Animals; Cysteine; Ferrous Compounds; Liver; Metallothionein; Rabbits; Spectroscopy, Mossbauer | 1994 |
Purification and properties of rat cysteine-rich intestinal protein.
Topics: Amino Acid Sequence; Animals; Binding, Competitive; Carrier Proteins; Chromatography, Gel; Chromatography, Ion Exchange; Cysteine; Electrophoresis, Polyacrylamide Gel; Intestinal Mucosa; Intestine, Small; LIM Domain Proteins; Male; Mass Spectrometry; Metallothionein; Molecular Sequence Data; Molecular Weight; Rats; Rats, Sprague-Dawley; Zinc; Zinc Fingers; Zinc Radioisotopes | 1994 |
Zinc transport and metallothionein induction in primary cultures of rabbit kidney proximal cells.
Topics: Animals; Cadmium; Cell Membrane; Cells, Cultured; Cysteine; Kidney Tubules, Proximal; Kinetics; Male; Metallothionein; Rabbits; Sulfur Radioisotopes; Zinc; Zinc Radioisotopes | 1994 |
Turnover rate of metallothionein and cadmium in Mytilus edulis.
Topics: Animals; Bivalvia; Cadmium; Cysteine; Half-Life; Metallothionein; Radioisotope Dilution Technique; Sulfur Radioisotopes; Time Factors | 1993 |
Copper- and silver-substituted yeast metallothioneins: sequential 1H NMR assignments reflecting conformational heterogeneity at the C terminus.
Topics: Amino Acid Sequence; Binding Sites; Copper; Cysteine; Hydrogen; Ligands; Magnetic Resonance Spectroscopy; Metallothionein; Molecular Sequence Data; Protein Conformation; Saccharomyces cerevisiae; Silver | 1993 |
A two-dimensional NMR study of Co(II)7 rabbit liver metallothionein.
Topics: Animals; Cations, Divalent; Cobalt; Cysteine; In Vitro Techniques; Liver; Magnetic Resonance Spectroscopy; Metallothionein; Protein Conformation; Rabbits | 1993 |
Identification of cysteine residues alkylated with 3-bromopropylamine by protein sequence analysis.
Topics: Alkylating Agents; Alkylation; Cysteine; Metallothionein; Muramidase; Phenylthiohydantoin; Propylamines; Proteins; Sequence Analysis | 1993 |
Normal metallothionein synthesis in fibroblasts obtained from children with Indian childhood cirrhosis or copper-associated childhood cirrhosis.
Topics: Autoradiography; Cells, Cultured; Child; Child, Preschool; Copper; Cysteine; Electrophoresis, Polyacrylamide Gel; Female; Fibroblasts; Humans; India; Infant; Liver Cirrhosis; Male; Metallothionein; Sulfur Radioisotopes; Zinc | 1995 |
Characterization and expression of metallothionein-like genes in cotton.
Topics: Amino Acid Sequence; Conserved Sequence; Cysteine; Exons; Gene Expression Regulation, Plant; Genes, Plant; Gossypium; Introns; Metallothionein; Molecular Sequence Data; Multigene Family; Plant Proteins; Plant Roots; Promoter Regions, Genetic; Restriction Mapping; Sequence Homology, Amino Acid | 1996 |
Role of metallothionein and other antioxidants in scavenging superoxide radicals and their possible role in neuroprotection.
Topics: Acetylcysteine; Animals; Antioxidants; Brain Chemistry; Cysteine; Electrophoresis, Polyacrylamide Gel; Free Radical Scavengers; Glutathione; Male; Metallothionein; Mice; Mice, Inbred C57BL; Nervous System Diseases; Nitrites; Superoxides | 1996 |
Construction and expression of bi-functional proteins of single-chain Fv with effector domains.
Topics: Amino Acid Sequence; Animals; Antibodies, Bispecific; Base Sequence; Cysteine; DNA; Humans; Immunoglobulin Fragments; Metallothionein; Mice; Models, Molecular; Molecular Structure; Pichia; Protein Conformation; Protein Engineering; Recombinant Fusion Proteins | 1996 |
Changes in abundance of an abscisic acid-responsive, early cysteine-labeled metallothionein transcript during pollen embryogenesis in bread wheat (Triticum aestivum).
Topics: Abscisic Acid; Cysteine; Metallothionein; Molecular Sequence Data; Plant Proteins; Pollen; RNA, Messenger; Triticum | 1996 |
Comparison of the response of serum ceruloplasmin and cholesterol, and of tissue ascorbic acid, metallothionein, and nonprotein sulfhydryl in rats to the dietary level of cystine and cysteine.
Topics: Animals; Ascorbic Acid; Ceruloplasmin; Cholesterol; Cysteine; Cystine; Diet; Eating; Male; Metallothionein; Rats; Rats, Wistar; Sulfhydryl Compounds; Thiobarbituric Acid Reactive Substances | 1996 |
Semi-empirical simulation of Zn/Cd binding site preference in the metal binding domains of mammalian metallothionein.
Topics: Animals; Binding Sites; Cadmium; Computer Simulation; Cysteine; Metallothionein; Models, Molecular; Movement; Thermodynamics; Zinc | 1996 |
A mutant metallothionein which has inverse fragment composition exhibits high cadmium-binding ability.
Topics: Alanine; Amino Acid Sequence; Binding Sites; Cadmium; Cysteine; Escherichia coli; Humans; Metallothionein; Molecular Sequence Data; Point Mutation; Recombinant Proteins | 1997 |
Uptake of Cd-metallothionein into LLC-PK1 cells: a comparative study with CdCl2.
Topics: Animals; Cadmium Chloride; Cysteine; Glutathione; Hydrogen-Ion Concentration; Kinetics; LLC-PK1 Cells; Metallothionein; Rats; Swine; Temperature | 1997 |
Metallothionein induction in calcifying growth plate cartilage chondrocytes.
Topics: Animals; Butyrates; Butyric Acid; Cadmium Chloride; Cells, Cultured; Chickens; Chlorides; Culture Media; Cysteine; Dexamethasone; Dihydroxycholecalciferols; Growth Plate; Interleukin-1; Metallothionein; Methionine; Zinc Compounds | 1996 |
Effects of amino acid replacements on cadmium binding of metallothionein alpha-fragment.
Topics: Amino Acid Sequence; Cadmium; Cysteine; Dithionitrobenzoic Acid; Gene Expression; Genetic Vectors; Humans; Metallothionein; Molecular Sequence Data; Recombinant Proteins; Structure-Activity Relationship | 1997 |
Role of transchelation in the uptake of 99mTc-MAb in liver and kidney.
Topics: Animals; Antibodies, Monoclonal; Chelating Agents; Cysteine; Dose-Response Relationship, Drug; Glutathione; Kidney; Liver; Male; Metallothionein; Mice; Mice, Inbred BALB C; Technetium; Time Factors; Tissue Distribution | 1997 |
Conversion of nitroxide radicals by phenolic and thiol antioxidants.
Topics: Antioxidants; Chromans; Cyclic N-Oxides; Cysteine; Dimethyl Sulfoxide; Electron Spin Resonance Spectroscopy; Ethanol; Free Radical Scavengers; Free Radicals; Glutathione; Hydroxyl Radical; Mercaptoethanol; Metallothionein; Nitrogen Oxides; Phenols; Sulfhydryl Compounds | 1997 |
Identification of metallothionein receptors in human astrocytes.
Topics: Amino Acid Sequence; Analysis of Variance; Astrocytes; Cells, Cultured; Cysteine; Dose-Response Relationship, Drug; Fluorescein-5-isothiocyanate; Fluorescent Dyes; Glutathione; Humans; Metallothionein; Molecular Sequence Data; Receptors, Cell Surface; Time Factors; Zinc | 1997 |
Role of glutathione in nitric oxide-dependent regulation of energy metabolism in rat hepatoma cells.
Topics: Acetylcysteine; Adenosine Diphosphate; Animals; Cysteine; Digitonin; Dose-Response Relationship, Drug; Energy Metabolism; Glutathione; Liver Neoplasms, Experimental; Male; Mercaptoethanol; Metallothionein; Mitochondria; Nitric Oxide; Nitroso Compounds; Rats; Rats, Inbred Strains; S-Nitrosoglutathione; S-Nitrosothiols; Time Factors | 1998 |
Cysteine contributions to metal binding preference for Zn/Cd in the beta-domain of metallothionein.
Topics: Cadmium; Cysteine; Metallothionein; Protein Binding; Thermodynamics; Zinc | 1998 |
Induction of drug resistance to gold sodium thiomalate in a monocyte cell line, THP-1.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; ATP Binding Cassette Transporter, Subfamily B, Member 1; Blotting, Western; Cell Line; Cysteine; Cytoplasm; Dose-Response Relationship, Drug; Drug Resistance; Fluorescent Antibody Technique, Indirect; Gold Sodium Thiomalate; Humans; Metallothionein; Monocytes; Sensitivity and Specificity | 1998 |
Determination of metallothionein content in hepatoma cells by differential pulse polarography.
Topics: Animals; Ascorbic Acid; Cadmium Chloride; Cell Survival; Chlorides; Cysteine; Dose-Response Relationship, Drug; Liver Neoplasms, Experimental; Metallothionein; Polarography; Rats; Reproducibility of Results; Tumor Cells, Cultured; Zinc Compounds | 1998 |
The 2.03 signal as an indicator of dinitrosyl-iron complexes with thiol-containing ligands.
Topics: Ammonium Sulfate; Animals; Cattle; Cysteine; Dioctyl Sulfosuccinic Acid; Electron Spin Resonance Spectroscopy; Freezing; Glutathione; Hemoglobins; Horses; Iron; Metallothionein; Nitrogen Oxides; Serum Albumin; Sodium Dodecyl Sulfate; Sulfhydryl Compounds | 1998 |
Replacement of terminal cysteine with histidine in the metallothionein alpha and beta domains maintains its binding capacity.
Topics: Amino Acid Sequence; Animals; Binding Sites; Cadmium; Circular Dichroism; Cysteine; Escherichia coli; Histidine; Mass Spectrometry; Metallothionein; Mice; Molecular Sequence Data; Mutagenesis, Site-Directed; Peptide Fragments; Protein Conformation; Recombinant Proteins; Spectrophotometry, Ultraviolet; Zinc | 1999 |
Why reversing the sequence of the alpha domain of human metallothionein-2 does not change its metal-binding and folding characteristics.
Topics: Amino Acid Sequence; Animals; Cadmium; Circular Dichroism; Cysteine; Dinitrobenzenes; Humans; Metallothionein; Molecular Sequence Data; Peptides; Protein Binding; Protein Structure, Tertiary; Rats | 1999 |
Nitric oxide induces Zn2+ release from metallothionein by destroying zinc-sulphur clusters without concomitant formation of S-nitrosothiol.
Topics: Cysteine; Cystine; Humans; Hydrogen-Ion Concentration; In Vitro Techniques; Kinetics; Mercaptoethanol; Metallothionein; Nitric Oxide; Nitroso Compounds; S-Nitrosothiols; Sulfur; Zinc | 1999 |
Molecular dynamics simulation of metallothionein-drug complexes.
Topics: Binding Sites; Chemical Phenomena; Chemistry, Physical; Chlorambucil; Computer Simulation; Crystallography, X-Ray; Cysteine; Mechlorethamine; Melphalan; Metallothionein; Models, Structural; Nitrogen Mustard Compounds; Protein Binding; Zinc | 2000 |
High resolution solution structure of the protein part of Cu7 metallothionein.
Topics: Amino Acid Sequence; Binding Sites; Carrier Proteins; Copper; Cysteine; Fungal Proteins; Metallothionein; Models, Molecular; Molecular Sequence Data; Nuclear Magnetic Resonance, Biomolecular; Protein Conformation; Saccharomyces cerevisiae; Silver; Solutions | 2000 |
Voltammetry on mercury and carbon electrodes as a tool for studies of metallothionein interactions with metal ions.
Topics: Animals; Cadmium; Carbon; Cysteine; Electrochemistry; Electrodes; Glutamine; Hydrogen-Ion Concentration; Ions; Liver; Mercury; Metallothionein; Peptides; Rabbits; Zinc | 2000 |
Metallothionein, nitric oxide and zinc homeostasis in vascular endothelial cells.
Topics: Animals; Antioxidants; Cells, Cultured; Chelating Agents; Cysteine; Drug Interactions; Endothelium, Vascular; Ethylenediamines; Fluorescent Dyes; Homeostasis; Metallothionein; Mice; Mice, Knockout; Nitric Oxide; Nitroso Compounds; Oxidation-Reduction; Pulmonary Artery; Quinolones; S-Nitrosothiols; Sheep; Tosyl Compounds; Zinc | 2000 |
Steric effect and effect of metal coordination on the reactivity of nitric oxide with cysteine-containing proteins under anaerobic conditions.
Topics: Anaerobiosis; Cysteine; Electrophoresis, Polyacrylamide Gel; Hydrogen-Ion Concentration; Metallothionein; Metals; Nitric Oxide; Protein Binding; Protein Conformation; Proteins; Serum Albumin, Bovine; Zinc | 2000 |
Protection from radiation-induced DNA single-strand breaks by induction of nuclear metallothionein.
Topics: Aerobiosis; Cell Hypoxia; Cell Nucleus; Cysteine; DNA Damage; DNA, Neoplasm; Female; Glutathione; Humans; Metallothionein; Radiation-Protective Agents; Temperature; Tumor Cells, Cultured; Zinc | 2000 |
Molecular-dynamics simulation of the beta domain of metallothionein with a semi-empirical treatment of the metal core.
Topics: Animals; Cadmium; Computer Simulation; Crystallography, X-Ray; Cysteine; Hydrogen Bonding; Metallothionein; Models, Chemical; Models, Molecular; Motion; Nuclear Magnetic Resonance, Biomolecular; Rats; Zinc | 2000 |
The mitochondrial copper metallochaperone Cox17 exists as an oligomeric, polycopper complex.
Topics: Blotting, Western; Cation Transport Proteins; Copper; Cysteine; Dimerization; Dithiothreitol; Electron Transport Complex IV; Escherichia coli; Glutathione Transferase; Macromolecular Substances; Metalloproteins; Metallothionein; Mitochondria; Molecular Chaperones; Mutagenesis, Site-Directed; Plasmids; Protein Biosynthesis; Proteins; Recombinant Proteins; Spectrophotometry, Ultraviolet; Spectrum Analysis; X-Rays | 2001 |
Structure-reactivity relationships among metallothionein three-metal domains: role of non-cysteine amino acid residues in lobster metallothionein and human metallothionein-3.
Topics: Amino Acid Sequence; Animals; Binding Sites; Calorimetry; Computer Graphics; Cysteine; Humans; Hydrogen Bonding; Kinetics; Metallothionein; Models, Molecular; Molecular Sequence Data; Nephropidae; Nuclear Magnetic Resonance, Biomolecular; Peptide Fragments; Protein Conformation; Protein Structure, Secondary; Rabbits; Thermodynamics | 2000 |
Cysteine-independent polymerization of metallothioneins in solutions and in crystals.
Topics: Amino Acid Sequence; Animals; Binding Sites; Conserved Sequence; Crystallization; Cysteine; Dimerization; Metallothionein; Models, Molecular; Molecular Sequence Data; Polymers; Rabbits; Rats; Sequence Alignment; Solutions; Static Electricity | 2000 |
Differential fluorescence labeling of cysteinyl clusters uncovers high tissue levels of thionein.
Topics: Animals; Brain; Chromatography, High Pressure Liquid; Cysteine; Fluorescent Dyes; Kidney; Liver; Metallothionein; Rats | 2001 |
A metallothionein containing a zinc finger within a four-metal cluster protects a bacterium from zinc toxicity.
Topics: Amino Acid Sequence; Bacterial Proteins; Cyanobacteria; Cysteine; Drug Resistance, Microbial; Magnetic Resonance Spectroscopy; Metallothionein; Molecular Sequence Data; Protein Conformation; Protein Structure, Tertiary; Sequence Alignment; Sequence Homology, Amino Acid; Spectrometry, Mass, Electrospray Ionization; Structure-Activity Relationship; Zinc; Zinc Fingers | 2001 |
Catalytic oxidation of zinc/sulfur coordination sites in proteins by selenium compounds.
Topics: Anticarcinogenic Agents; Catalysis; Colorimetry; Cysteine; Humans; Hydrogen-Ion Concentration; Kinetics; Ligands; Metallothionein; Models, Chemical; Nitriles; Oxidation-Reduction; Protein Binding; Selenium; Spectrophotometry, Ultraviolet; Sulfur; Zinc | 2001 |
Oxidative dimerization in metallothionein is a result of intermolecular disulphide bonds between cysteines in the alpha-domain.
Topics: Animals; Cysteine; Dimerization; In Vitro Techniques; Magnetic Resonance Spectroscopy; Metallothionein; Mice; Models, Molecular; Oxidation-Reduction; Protein Structure, Quaternary; Protein Structure, Tertiary; Rabbits | 2001 |
Model reactions of Cr (VI) with DNA mediated by thiol species.
Topics: Animals; Cattle; Chromium; Cross-Linking Reagents; Cysteine; DNA; DNA Adducts; DNA Damage; DNA-Binding Proteins; Glutathione; Metallothionein; Models, Chemical; Oxidation-Reduction; Sulfhydryl Compounds; Transcription Factor TFIIIA; Transcription Factors; Xenopus laevis; Zinc Fingers | 2001 |
Cadmium resistance conferred to yeast by a non-metallothionein-encoding gene of the earthworm Enchytraeus.
Topics: Amino Acid Sequence; Animals; Aspartic Acid; Blotting, Western; Cadmium; Cysteine; DNA, Complementary; Dose-Response Relationship, Drug; Drug Resistance; Metallothionein; Mice; Microscopy, Confocal; Models, Genetic; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; Oligochaeta; Phenotype; Proline; Protein Binding; Protein Structure, Tertiary; Proteins; Sequence Homology, Amino Acid | 2002 |
Nitric oxide-induced changes in intracellular zinc homeostasis are mediated by metallothionein/thionein.
Topics: Animals; Cells, Cultured; Chelating Agents; Cysteine; Endothelium, Vascular; Ergothioneine; Ethylenediamines; Female; Fibroblasts; Fluorescent Dyes; Gene Expression; Homeostasis; Lung; Male; Metallothionein; Mice; Mice, Inbred C57BL; Mice, Knockout; Nitric Oxide; Nitric Oxide Donors; Pulmonary Artery; Quinolones; S-Nitrosothiols; Sheep; Spectrometry, Fluorescence; Tosyl Compounds; Zinc | 2002 |
Alterations of tissue glutathione levels and metallothionein mRNA in rainbow trout during single and combined exposure to cadmium and zinc.
Topics: Animals; Cadmium; Chromatography, High Pressure Liquid; Cysteine; Dose-Response Relationship, Drug; Gills; Glutathione; Glutathione Disulfide; Liver; Metallothionein; Oncorhynchus mykiss; Organ Specificity; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Time Factors; Zinc | 2002 |
Quantitation of S-nitrosothiols in cells and biological fluids.
Topics: Albumins; Cysteine; Dose-Response Relationship, Drug; Fluorescein; Glutathione; Indicators and Reagents; Metallothionein; Microscopy, Fluorescence; Models, Chemical; Nitric Oxide; S-Nitrosothiols; Time Factors; Ultraviolet Rays | 2002 |
Oxidation of biological thiols by highly reactive disulfide-S-oxides.
Topics: Cysteine; Disulfides; Glutathione; Glutathione Disulfide; Hydrogen Peroxide; Metallothionein; Oxidants; Oxidation-Reduction; Oxidative Stress; Oxides; Reactive Oxygen Species; Sensitivity and Specificity; Sulfhydryl Compounds; Sulfur | 2002 |
Multiple bacteria encode metallothioneins and SmtA-like zinc fingers.
Topics: Amino Acid Sequence; Anabaena; Bacteria; Bacterial Proteins; Base Sequence; Binding Sites; Cysteine; DNA, Bacterial; Escherichia coli; Escherichia coli Proteins; Genes, Bacterial; Hydrogen-Ion Concentration; Metallothionein; Models, Molecular; Molecular Sequence Data; Nuclear Magnetic Resonance, Biomolecular; Pseudomonas aeruginosa; Pseudomonas putida; Sequence Homology, Amino Acid; Zinc; Zinc Fingers | 2002 |
Construction of alpha-alpha domains structure in recombinant monkey metallothionein-1.
Topics: Animals; Cadmium; Cysteine; Dithionitrobenzoic Acid; Haplorhini; Hydrogen-Ion Concentration; Metallothionein; Mutation; Protein Binding; Protein Denaturation; Protein Structure, Tertiary; Recombinant Proteins | 2002 |
A fluorescence resonance energy transfer sensor for the beta-domain of metallothionein.
Topics: Cadmium; Circular Dichroism; Cysteine; DNA, Complementary; Escherichia coli; Fluorescence Resonance Energy Transfer; Humans; Maleimides; Metallothionein; Models, Molecular; Mutagenesis, Site-Directed; Mutation; Protein Conformation; Protein Isoforms; Protein Structure, Tertiary; Proteins; Recombinant Fusion Proteins; Recombinant Proteins; Spectrometry, Fluorescence; Sulfhydryl Compounds; Time Factors; Ultraviolet Rays; Zinc | 2003 |
Reversible folding of cysteine-rich metallothionein by an overcritical reaction path.
Topics: Animals; Circular Dichroism; Cysteine; In Vitro Techniques; Light; Metallothionein; Protein Folding; Scattering, Radiation; Spectrophotometry, Atomic; Thermodynamics; Zinc | 2003 |
Bioadsorption of cadmium ion by cell surface-engineered yeasts displaying metallothionein and hexa-His.
Topics: Adsorption; Cadmium; Cell Membrane; Culture Media; Cysteine; Edetic Acid; Genetic Engineering; Histidine; Metallothionein; Plasmids; Saccharomyces cerevisiae | 2003 |
Gel filtration chromatography of metallothionein obtained from rabbit liver.
Topics: Animals; Chromatography, Gel; Cysteine; Cytosol; Metallothionein; Rabbits; Zinc | 2003 |
Solution structure of Cu6 metallothionein from the fungus Neurospora crassa.
Topics: Amino Acid Motifs; Amino Acid Sequence; Animals; Carrier Proteins; Copper; Cysteine; Cystine; Humans; Magnetic Resonance Spectroscopy; Metallothionein; Metals; Mice; Models, Chemical; Models, Molecular; Molecular Sequence Data; Neurospora crassa; Peptides; Protein Conformation; Protein Folding; Protein Structure, Tertiary; Saccharomyces cerevisiae; Sulfur | 2004 |
How to hide zinc in a small protein.
Topics: Amino Acid Sequence; Bacteria; Cadmium; Cysteine; Dimerization; Histidine; Ligands; Lysine; Metallothionein; Molecular Sequence Data; Protein Binding; Protein Folding; Proteins; Sequence Alignment; Sulfhydryl Compounds; Sulfides; Zinc; Zinc Compounds; Zinc Fingers | 2005 |
Use of a substrate/alliinase combination to generate antifungal activity in situ.
Topics: Carbon-Sulfur Lyases; Cysteine; Disulfides; Fungicides, Industrial; Magnaporthe; Metallothionein; Sulfinic Acids; Zinc | 2005 |
Susceptibility of actin to modification by 4-hydroxy-2-nonenal.
Topics: Actins; Albumins; Aldehydes; Animals; Antibodies, Monoclonal; Blotting, Western; Cysteine; Ferric Compounds; Glyceraldehyde-3-Phosphate Dehydrogenases; Hemocyanins; Histidine; Kidney; Kidney Neoplasms; Lysine; Male; Metallothionein; Nitrilotriacetic Acid; Rats; Rats, Wistar; Specific Pathogen-Free Organisms; Superoxide Dismutase | 2005 |
Domain-specific fluorescence resonance energy transfer (FRET) sensors of metallothionein/thionein.
Topics: Biosensing Techniques; Cysteine; Ergothioneine; Fluorescence Resonance Energy Transfer; Fluorescent Dyes; Humans; Metallothionein; Models, Molecular; Mutagenesis, Site-Directed; Mutation; Naphthalenesulfonates; Protein Conformation; Protein Isoforms; Recombinant Proteins; Sulfhydryl Reagents; Tryptophan; Zinc | 2005 |
Characterization of expression and stability of recombinant cystein-rich protein human MT1A from yeast.
Topics: Carbon; Chlorides; Cysteine; Gene Expression; Hemolysis; Histidine; Humans; Metallothionein; Recombinant Proteins; Saccharomyces cerevisiae; Zinc Compounds | 2005 |
Metallothionein mediates leukocyte chemotaxis.
Topics: Actins; Amino Acid Sequence; Animals; Antibodies, Monoclonal; Chemokine CCL17; Chemokine CXCL12; Chemokines, CC; Chemokines, CXC; Chemotaxis, Leukocyte; Cysteine; Dose-Response Relationship, Drug; Humans; Jurkat Cells; Metallothionein; Microscopy, Video; Molecular Sequence Data; Rabbits; Sequence Alignment; Sequence Homology, Amino Acid | 2005 |
Metallothionein disulfides are present in metallothionein-overexpressing transgenic mouse heart and increase under conditions of oxidative stress.
Topics: Animals; Antineoplastic Agents; Blotting, Western; Chromatography, High Pressure Liquid; Cysteine; Disulfides; Dithiothreitol; Doxorubicin; Electrophoresis, Polyacrylamide Gel; Ethylmaleimide; Iodoacetamide; Mass Spectrometry; Metallothionein; Mice; Mice, Transgenic; Myocardium; Oxidative Stress; Peptides; Protein Structure, Tertiary; Spectrometry, Mass, Electrospray Ionization; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Time Factors; Trypsin; Zinc | 2006 |
Survival of human metallothionein-2 transplastomic Chlamydomonas reinhardtii to ultraviolet B exposure.
Topics: Animals; Cells, Cultured; Chlamydomonas reinhardtii; Chlorophyll; Chloroplasts; Culture Media; Cysteine; Humans; Metallothionein; Metals; Photosynthesis; Tetrazolium Salts; Time Factors; Ultraviolet Rays | 2006 |
Aldehydes release zinc from proteins. A pathway from oxidative stress/lipid peroxidation to cellular functions of zinc.
Topics: Alcohol Dehydrogenase; Aldehydes; Animals; Cell Line, Tumor; Cysteine; Humans; Ligands; Lipid Peroxidation; Metallothionein; Oxidative Stress; Phosphorylation; Protein Isoforms; Protein Tyrosine Phosphatases; Rabbits; Zinc | 2006 |
Histidine ligands in bacterial metallothionein enhance cluster stability.
Topics: Amino Acid Sequence; Bacterial Proteins; Cadmium; Cysteine; Histidine; Ligands; Metallothionein; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; Protein Conformation; Protein Folding; Sequence Homology, Amino Acid; Static Electricity; Zinc | 2007 |
Isolation and preliminary characterization of a Cd-binding protein from Tenebrio molitor (Coleoptera).
Topics: Amino Acids; Animals; Chromatography, Gel; Chromatography, Ion Exchange; Cysteine; Mass Spectrometry; Metallothionein; Molecular Weight; Tenebrio | 2007 |
Toward a property/function relationship for metallothioneins: histidine coordination and unusual cluster composition in a zinc-metallothionein from plants.
Topics: Amino Acid Sequence; Cysteine; Databases, Protein; Deuterium; Histidine; Metallothionein; Plant Proteins; Sequence Alignment; Sequence Homology, Amino Acid | 2007 |
The conserved cysteine-rich domain of a tesmin/TSO1-like protein binds zinc in vitro and TSO1 is required for both male and female fertility in Arabidopsis thaliana.
Topics: Amino Acid Sequence; Arabidopsis; Arabidopsis Proteins; Cysteine; Drosophila Proteins; Gene Expression Regulation, Plant; Metallothionein; Molecular Sequence Data; Nuclear Proteins; Protein Binding; Protein Structure, Tertiary; Zinc | 2007 |
The significance of disulfide bonding in biological activity of HB-EGF, a mutagenesis approach.
Topics: Animals; Cell Line; Cell Nucleus; Cloning, Molecular; Cysteine; Disulfides; ErbB Receptors; Fibroblasts; Heparin-binding EGF-like Growth Factor; Humans; Intercellular Signaling Peptides and Proteins; Metallothionein; Mice; Mutagenesis, Site-Directed; Phosphorylation; Promoter Regions, Genetic; RNA, Messenger; Serine; Tyrosine | 2008 |
Cloning, expression, and characterization of cadmium-induced metallothionein-2 from the earthworms Metaphire posthuma and Polypheretima elongata.
Topics: Amino Acid Motifs; Amino Acid Sequence; Animals; Binding Sites; Biomarkers; Cadmium Chloride; Cloning, Molecular; Conserved Sequence; Copper; Cysteine; DNA, Complementary; Environmental Monitoring; Free Radical Scavengers; Gene Expression Profiling; Kinetics; Metallothionein; Molecular Sequence Data; Molecular Weight; Oligochaeta; Phylogeny; Recombinant Proteins; Sequence Alignment; Sequence Analysis, Protein; Soil Pollutants; Zinc | 2009 |
Induction of metallothionein I by arsenic via metal-activated transcription factor 1: critical role of C-terminal cysteine residues in arsenic sensing.
Topics: Animals; Arsenic; beta-Galactosidase; Blotting, Northern; Cells, Cultured; Chromatin Immunoprecipitation; Cysteine; DNA-Binding Proteins; Embryo, Mammalian; Fibroblasts; Immunoblotting; Liver Neoplasms, Experimental; Luciferases; Metallothionein; Mice; Mice, Knockout; NF-E2-Related Factor 2; Promoter Regions, Genetic; Reactive Oxygen Species; Response Elements; RNA, Messenger; Sulfhydryl Compounds; Transcription Factor MTF-1; Transcription Factors; Transcriptional Activation; Zinc | 2009 |
Conjugation of Au11 cluster with Cys-rich peptides containing the alpha-domain of metallothionein.
Topics: Amino Acid Sequence; Animals; Circular Dichroism; Cysteine; Gold; Metallothionein; Microscopy, Electron, Transmission; Molecular Sequence Data; Organometallic Compounds; Peptides; Protein Structure, Tertiary; Rats; Zinc Fingers | 2009 |
Reaction of human metallothionein-3 with cisplatin and transplatin.
Topics: Amino Acid Sequence; Antineoplastic Agents; Cadmium; Chelating Agents; Cisplatin; Cysteine; Humans; Hydrogen-Ion Concentration; Isotopes; Kinetics; Metallothionein; Metallothionein 3; Nerve Tissue Proteins; Nuclear Magnetic Resonance, Biomolecular; Protein Binding; Protein Isoforms; Protein Structure, Tertiary; Recombinant Proteins; Spectrometry, Mass, Electrospray Ionization; Spectrophotometry, Atomic; Stereoisomerism; Time Factors; Zinc | 2009 |
Hepatotoxicity of high oral dose (-)-epigallocatechin-3-gallate in mice.
Topics: Aldehydes; Animals; Antioxidants; Biomarkers; Catechin; Chemical and Drug Induced Liver Injury; Chromatography, High Pressure Liquid; Cysteine; Cytokines; Dose-Response Relationship, Drug; Immunohistochemistry; Lipid Peroxidation; Liver Function Tests; Male; Metallothionein; Mice; Oxidants; Oxidative Stress; Spectrometry, Mass, Electrospray Ionization; Survival Analysis | 2010 |
Zinc protects human peripheral blood lymphocytes from Cr(III)(phenanthroline)3-induced apoptosis.
Topics: Adenosine Triphosphate; Apoptosis; Caspase 3; Catalase; Cell Separation; Cell Survival; Chromium; Cysteine; DNA; DNA Fragmentation; Electrophoresis, Agar Gel; Humans; Ligands; Lymphocytes; Metallothionein; Microscopy, Electron, Transmission; Mitochondrial Membranes; Organometallic Compounds; Protective Agents; Reactive Oxygen Species; Silver Staining; Superoxide Dismutase; Thymidine; Zinc Compounds | 2010 |
The metal-binding properties of the blue crab copper specific CuMT-2: a crustacean metallothionein with two cysteine triplets.
Topics: Animals; Binding Sites; Brachyura; Cadmium; Copper; Cysteine; Ligands; Metallothionein; Metals; Recombinant Proteins; Zinc | 2010 |
Bismuth binding studies to the human metallothionein using electrospray mass spectrometry.
Topics: Antacids; Binding Sites; Bismuth; Cysteine; Humans; Metallothionein; Protein Binding; Protein Structure, Tertiary; Spectrometry, Mass, Electrospray Ionization | 2010 |
Reactivity of an antimetastatic organometallic ruthenium compound with metallothionein-2: relevance to the mechanism of action.
Topics: Amino Acid Sequence; Animals; Antineoplastic Agents; Cisplatin; Cymenes; Cysteine; Humans; Metallothionein; Molecular Sequence Annotation; Molecular Sequence Data; Organometallic Compounds; Protein Binding; Rabbits; Ruthenium Compounds; Sequence Alignment; Spectrometry, Mass, Electrospray Ionization; Zinc | 2009 |
Effects of gamma-ray-induced free radicals on the metal content and amino acid composition of human metallothionein-1.
Topics: Butyrates; Cystathionine; Cysteine; Gamma Rays; Homocysteine; Humans; Metallothionein; Methionine; Serine; Zinc | 2011 |
Metallothionein-inspired prototype of molecular pincer.
Topics: Amides; Cysteine; Imides; Lead; Metallothionein; Oxidation-Reduction; Zinc | 2011 |
Full quantum-mechanical structure of the human protein Metallothionein-2.
Topics: Amino Acid Sequence; Cadmium; Computer Simulation; Coordination Complexes; Cysteine; Electrochemistry; Humans; Metallothionein; Models, Molecular; Molecular Sequence Data; Protein Structure, Tertiary; Quantum Theory; Zinc | 2012 |
Metal binding properties and structure of a type III metallothionein from the metal hyperaccumulator plant Noccaea caerulescens.
Topics: Amino Acid Sequence; Brassicaceae; Cations, Divalent; Cysteine; Metallothionein; Metals, Heavy; Molecular Sequence Data; Plant Proteins; Protein Binding; Protein Conformation | 2012 |
Clustered metallothionein genes are co-regulated in rice and ectopic expression of OsMT1e-P confers multiple abiotic stress tolerance in tobacco via ROS scavenging.
Topics: Adaptation, Physiological; Chromosomes, Plant; Computational Biology; Conserved Sequence; Cysteine; Free Radical Scavengers; Gene Expression Regulation, Plant; Genes, Plant; Metallothionein; Multigene Family; Nicotiana; Oryza; Oxidative Stress; Plants, Genetically Modified; Reactive Oxygen Species; Salt-Tolerant Plants; Seeds; Sodium Chloride | 2012 |
Structural properties of metal-free apometallothioneins.
Topics: Benzoquinones; Cysteine; Hydrogen-Ion Concentration; Metallothionein; Metals; Models, Molecular; Protein Folding; Protein Structure, Secondary; Spectrometry, Mass, Electrospray Ionization | 2012 |
Bis(L-cysteinato)zincate(lI) as a coordination compound that induces metallothionein gene transcription without inducing cell-stress-related gene transcription.
Topics: Animals; Cell Line, Tumor; Coordination Complexes; Cysteine; Electrophoretic Mobility Shift Assay; Gene Expression; Humans; Hydrophobic and Hydrophilic Interactions; Metallothionein; Mice; Promoter Regions, Genetic; Transcription, Genetic; Transfection; Zinc | 2012 |
Oxidation reactivity of zinc-cysteine clusters in metallothionein.
Topics: Animals; Cadmium; Cysteine; Humans; Hydrogen Peroxide; Metallothionein; Models, Molecular; Oxidation-Reduction; Protein Structure, Tertiary; Quantum Theory; Sulfhydryl Compounds; Zinc | 2013 |
Tissue-specificity and phylogenetics of Pl-MT mRNA during Paracentrotus lividus embryogenesis.
Topics: Amino Acid Sequence; Animals; Blastocyst; Computational Biology; Cysteine; Embryonic Development; Endoderm; Fluorescent Antibody Technique, Indirect; Gastrula; Gene Expression Regulation, Developmental; Genetic Markers; In Situ Hybridization; Mesoderm; Metallothionein; Molecular Sequence Data; Organ Specificity; Paracentrotus; Phylogeny; Polymerase Chain Reaction; RNA, Messenger | 2013 |
Cysteine accessibility during As3+ metalation of the α- and β-domains of recombinant human MT1a.
Topics: Amino Acid Sequence; Arsenic; Benzoquinones; Cysteine; Escherichia coli; Humans; Metallothionein; Molecular Dynamics Simulation; Molecular Sequence Data; Protein Binding; Protein Folding; Protein Stability; Protein Structure, Tertiary; Recombinant Proteins; Spectrometry, Mass, Electrospray Ionization; Sulfhydryl Compounds | 2013 |
X-ray absorption spectroscopy proves the trigonal-planar sulfur-only coordination of copper(I) with high-affinity tripodal pseudopeptides.
Topics: Coordination Complexes; Copper; Cysteine; Ligands; Metallothionein; Nitrilotriacetic Acid; Peptidomimetics; Sulfur; X-Ray Absorption Spectroscopy | 2013 |
Actin cytoskeleton redox proteome oxidation by cadmium.
Topics: Actin Cytoskeleton; Animals; Cadmium; Cells, Cultured; Cysteine; Destrin; Environmental Pollutants; Fibroblasts; Gene Expression; Glutathione; Lung Diseases; Metabolic Networks and Pathways; Metallothionein; Mice; Mice, Inbred C57BL; Oxidation-Reduction; Oxidative Stress; Protein Transport; Proteome | 2013 |
Protection against acetaminophen-induced liver injury by allopurinol is dependent on aldehyde oxidase-mediated liver preconditioning.
Topics: Acetaminophen; Aldehyde Oxidase; Allopurinol; Animals; Chemical and Drug Induced Liver Injury; Cysteine; Drug Overdose; Glutathione; JNK Mitogen-Activated Protein Kinases; Liver; Male; Metallothionein; Mice; Mice, Inbred C3H; Mitochondria; Oxypurinol; Phosphorylation; Xanthine Oxidase | 2014 |
Quantitation of human metallothionein isoforms: a family of small, highly conserved, cysteine-rich proteins.
Topics: Alternative Splicing; Breast Neoplasms; Cadmium; Cells, Cultured; Cerebrum; Cysteine; Cytosol; Epithelial Cells; Female; Humans; Kidney; MCF-7 Cells; Metallothionein; Methionine; Organ Specificity; Peptides; Protein Isoforms; Proteomics; Reproducibility of Results; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization | 2014 |
Metallothionein 2 (SaMT2) from Sedum alfredii Hance confers increased Cd tolerance and accumulation in yeast and tobacco.
Topics: Antioxidants; Cadmium; Cysteine; Gene Expression Regulation, Plant; Hydrogen Peroxide; Metallothionein; Nicotiana; Plant Roots; Plant Shoots; Plants, Genetically Modified; Sedum; Yeasts; Zinc | 2014 |
An optimized intein-mediated protein ligation approach for the efficient cyclization of cysteine-rich proteins.
Topics: Amino Acid Sequence; Cyclization; Cysteine; Endopeptidases; Escherichia coli; Gene Expression; Hydrogen-Ion Concentration; Inteins; Kinetics; Metallothionein; Molecular Sequence Data; Peptides, Cyclic; Plant Proteins; Potyvirus; Protein Engineering; Protein Folding; Protein Stability; Protein Structure, Secondary; Protein Structure, Tertiary; Proteolysis; Recombinant Proteins; Thermodynamics; Triticum | 2014 |
Metalation kinetics of the human α-metallothionein 1a fragment is dependent on the fluxional structure of the apo-protein.
Topics: Benzoquinones; Cadmium; Circular Dichroism; Cysteine; Humans; Hydrogen-Ion Concentration; Kinetics; Metallothionein; Molecular Dynamics Simulation; Protein Denaturation; Protein Structure, Tertiary; Spectrometry, Mass, Electrospray Ionization | 2015 |
Carryover of cadmium from feed in growing pigs.
Topics: Administration, Oral; Animal Feed; Animals; Cadmium; Cadmium Chloride; Cysteine; European Union; Kidney; Liver; Male; Metallothionein; Models, Statistical; No-Observed-Adverse-Effect Level; Swine; Tissue Distribution | 2015 |
Identification and expression of an atypical isoform of metallothionein in the African clawed frog Xenopus laevis.
Topics: Aging; Amino Acid Sequence; Animals; Base Sequence; Biological Evolution; Cloning, Molecular; Computational Biology; Cysteine; DNA, Complementary; Gene Expression Regulation; Metallothionein; Molecular Sequence Data; Phylogeny; Protein Isoforms; Real-Time Polymerase Chain Reaction; RNA; Xenopus laevis | 2015 |
Interactive effects of sulfur and chromium on antioxidative defense systems and BnMP1 gene expression in canola (Brassica napus L.) cultivars differing in Cr(VI) tolerance.
Topics: Antioxidants; Brassica napus; Chlorophyll; Chromium; Cysteine; Gene Expression Regulation, Plant; Lipid Peroxidation; Metallothionein; Seedlings; Sulfur | 2015 |
Putting the pieces into place: Properties of intact zinc metallothionein 1A determined from interaction of its isolated domains with carbonic anhydrase.
Topics: Amino Acid Sequence; Animals; Binding Sites; Cadmium; Carbonic Anhydrases; Cysteine; Humans; Kinetics; Metallothionein; Protein Binding; Protein Structure, Tertiary; Zinc | 2015 |
Metallothionein-1 as a biomarker of altered redox metabolism in hepatocellular carcinoma cells exposed to sorafenib.
Topics: Antineoplastic Agents; Biomarkers; Carcinoma, Hepatocellular; Cell Line, Tumor; Cysteine; Gene Expression Regulation, Neoplastic; Humans; Liver Neoplasms; Metallothionein; NF-E2-Related Factor 2; Niacinamide; Oxidation-Reduction; Oxidative Stress; Phenylurea Compounds; Prognosis; Promoter Regions, Genetic; Protein Kinase Inhibitors; Sorafenib; Transcription, Genetic | 2016 |
Remediation of cadmium toxicity in field peas (Pisum sativum L.) through exogenous silicon.
Topics: Cadmium; Catalase; Cysteine; Glutathione; Glutathione Reductase; Iron; Metallothionein; Methionine; Peroxidase; Phytochelatins; Pisum sativum; Plant Roots; Plant Shoots; Reactive Oxygen Species; Silicon; Stress, Physiological; Superoxide Dismutase; Trace Elements | 2017 |
Independent metal-thiolate cluster formation in C-terminal Cys-rich region of a rice type 1 metallothionein isoform.
Topics: Amino Acid Sequence; Cloning, Molecular; Cysteine; Metallothionein; Mutation; Organometallic Compounds; Oryza; Plant Proteins; Protein Stability | 2017 |
Enhanced metal tolerance correlates with heterotypic variation in SpMTL, a metallothionein-like protein from the hyperaccumulator Sedum plumbizincicola.
Topics: Adaptation, Physiological; Amino Acid Sequence; Arabidopsis; Biological Transport; Cadmium; Chelating Agents; Cysteine; Gene Expression Regulation, Plant; Inactivation, Metabolic; Metallothionein; Metals; Plant Proteins; Plant Roots; Plants, Genetically Modified; RNA, Messenger; Saccharomyces cerevisiae; Sedum; Species Specificity; Zinc | 2017 |
Selective cysteine modification of metal-free human metallothionein 1a and its isolated domain fragments: Solution structural properties revealed via ESI-MS.
Topics: Cysteine; Humans; Hydrogen-Ion Concentration; Mass Spectrometry; Metallothionein; Protein Domains; Protein Folding; Protein Processing, Post-Translational | 2017 |
Formation of oxidative and non-oxidative dimers in metallothioneins: Implications for charge-state analysis for structural determination.
Topics: Cysteine; Dimerization; Metallothionein; Oxidation-Reduction; Protein Conformation; Spectrometry, Mass, Electrospray Ionization | 2017 |
Functional comparision between truncated MTT1 and truncated MTT2 from Tetrahyemna thermophila.
Topics: Amino Acid Sequence; Cadmium; Copper; Cysteine; Dithionitrobenzoic Acid; Escherichia coli; Metallothionein; Protein Stability; Protozoan Proteins; Sequence Deletion; Stress, Physiological; Tetrahymena | 2018 |
Metallothioneins of the urochordate Oikopleura dioica have Cys-rich tandem repeats, large size and cadmium-binding preference.
Topics: Amino Acid Sequence; Animals; Cadmium; Cysteine; Gene Expression Regulation; Metallothionein; Promoter Regions, Genetic; Regulatory Elements, Transcriptional; Sequence Homology; Tandem Repeat Sequences; Urochordata | 2018 |
Carbon monoxide sensitizes cisplatin-resistant ovarian cancer cell lines toward cisplatin via attenuation of levels of glutathione and nuclear metallothionein.
Topics: Antineoplastic Agents; Carbon Monoxide; Cell Line, Tumor; Cell Nucleus; Cisplatin; Cystathionine beta-Synthase; Cysteine; Drug Resistance, Neoplasm; Female; Glutathione; Humans; Metallothionein; Ovarian Neoplasms | 2019 |
Over-expression of CarMT gene modulates the physiological performance and antioxidant defense system to provide tolerance against drought stress in Arabidopsis thaliana L.
Topics: Adaptation, Physiological; Antioxidants; Arabidopsis; Cicer; Cysteine; Droughts; Gene Expression Regulation, Plant; Germination; Metallothionein; Plant Proteins; Plants, Genetically Modified; Proline; Stress, Physiological | 2019 |
Expression of Rice Metallothionein Isoforms in Escherichia coli Enhances the Accumulation of Trivalent and Hexavalent Chromium.
Topics: Amino Acid Sequence; Cations; Chromium; Cysteine; Escherichia coli; Hydrogen-Ion Concentration; Metallothionein; Oryza; Plant Proteins; Protein Binding; Protein Isoforms; Recombinant Proteins | 2019 |
Impact of naturally occurring serine/cysteine variations on the structure and function of Pseudomonas metallothioneins.
Topics: Amino Acid Sequence; Bacterial Proteins; Cysteine; Edetic Acid; Magnetic Resonance Spectroscopy; Mass Spectrometry; Metallothionein; Pseudomonas; Serine | 2020 |
Triplet of cysteines - Coordinational riddle?
Topics: Cadmium; Coordination Complexes; Cysteine; Humans; Metallothionein; Nickel; Peptide Fragments; Zinc | 2020 |
Structurally restricted Bi(III) metallation of apo-βMT1a: metal-induced tangling.
Topics: Apoproteins; Bismuth; Cadmium; Cysteine; Humans; Metallothionein; Zinc | 2021 |
Comparative cisplatin reactivity towards human Zn7-metallothionein-2 and MTF-1 zinc fingers: potential implications in anticancer drug resistance.
Topics: Amino Acid Sequence; Antineoplastic Agents; Chelating Agents; Cisplatin; Coordination Complexes; Cysteine; DNA; DNA-Binding Proteins; Drug Resistance; Histidine; Humans; Metallothionein; Metals; Oligonucleotides; Transcription Factors; Zinc; Zinc Fingers | 2022 |
SaMT3 in Sedum alfredii drives Cd detoxification by chelation and ROS-scavenging via Cys residues.
Topics: Biodegradation, Environmental; Cadmium; Chelating Agents; Cysteine; Metallothionein; Plant Roots; Reactive Oxygen Species; Sedum; Soil Pollutants | 2022 |
Effects of Phytochelatin-like Gene on the Resistance and Enrichment of Cd
Topics: Aminoacyltransferases; Arabidopsis; Cadmium; Cysteine; Glutathione; Metallothionein; Nicotiana; Peptides; Phytochelatins; Plants, Genetically Modified | 2022 |
Role of the luminal composition on intestinal metal toxicity, bioavailability and bioreactivity: An in vitro approach based on the cell line RTgutGC.
Topics: Animals; Bicarbonates; Cadmium; Calcium; Cell Line; Chlorides; Copper; Cysteine; Metallothionein; Oncorhynchus mykiss; Silver; Water Pollutants, Chemical; Zinc | 2023 |
Functional characterization of rice metallothionein OsMT-I-Id: Insights into metal binding and heavy metal tolerance mechanisms.
Topics: Arsenic; Cadmium; Cysteine; Metallothionein; Metals, Heavy; Oryza; Saccharomyces cerevisiae | 2023 |