cysteine and mesna

cysteine has been researched along with mesna in 38 studies

Research

Studies (38)

TimeframeStudies, this research(%)All Research%
pre-199011 (28.95)18.7374
1990's5 (13.16)18.2507
2000's8 (21.05)29.6817
2010's12 (31.58)24.3611
2020's2 (5.26)2.80

Authors

AuthorsStudies
Wellinger, A; Wuhrmann, K1
Fahey, RC; Michael, BD; Vojnovic, B1
Bertram, B; Eisenbarth, J; Rajca, A; Wiessler, M1
Aas, P; Shaw, IC1
Conti-Tronconi, BM; Dunn, SM; Raftery, MA1
Schwieder, G; Wagner, T; Zink, M1
Czarnomska, A; Czyzewska-Szafran, H; Danysz, A; Jastrzebski, Z1
Jones, MS; Murrell, RD; Shaw, IC1
Clutterbuck, R; Jinks, S; Millar, BC; Millar, JL1
Burba-Anczewska, I; Danysz, A; Kłosiewicz, S; Pniewska, A; Wierzba, K1
Gardner, ML1
Hohorst, HJ; Jaschke, A; Voelcker, G; Wrabetz, E1
Aarsen, G; Cats, BP; de Bree, PK; Duran, M; Fokkens, RH; Nibbering, NM; Wadman, SK1
Cerny, T; Hartmann, B; Junker, E; Küpfer, A; Lauterburg, BH; Nguyen, T1
Cerny, T; Junker, E; Küpfer, A; Lauterburg, BH; Stofer-Vogel, B1
Bernstein, ML; Dubowy, RL; Fahey, RC; Newton, GL; Souid, AK1
Bolanowska-Higdon, W; Creaven, PJ; Meropol, NJ; Murphy, M; Pendyala, L; Perez, R; Schwartz, G; Zdanowicz, J1
Fahey, RC1
Hausheer, F; Murphy, M; Pendyala, L; Schwartz, G; Smith, P; Zdanowicz, J1
Booker, BM; Creaven, P; Pendyala, L; Perez, R; Smith, PF1
Bast, A; Boven, E; Hausheer, FH; Torun, E; van der Vijgh, WJ; Verschraagen, M1
Benesic, A; Freudinger, R; Gekle, M; Kirchhoff, A; Schwerdt, G; Wollny, B1
Hauser, PS; Ryan, RO1
Merkx, M; Raats, JM; Reulen, SW; van Baal, I1
Ayala, PY; Chen, S; Chen, X; Hausheer, FH; Huang, Q; Jair, KW; Kochat, H; Parker, AR; Petluru, PN; Shanmugarajah, D1
Helms, BA; Lempens, EH; Merkx, M1
García-Contreras, R; Jasso-Chávez, R; Lira-Silva, E; Marín-Hernández, A; Moreno-Sánchez, R; Santiago-Martínez, MG; Zepeda-Rodríguez, A1
Lorsch, JR; Mitchell, SF1
Bodalia, A; Cutler, MJ; Freeman, DJ; House, AA; Urquhart, BL; Velenosi, TJ1
Bedioui, F; Griveau, S; Liu, B; Xiao, J; Xu, H1
Ayala, PY; Badger, J; Hausheer, FH; Jair, K; Kochat, H; Leverett, BD; Logan, C; Nienaber, VL; Parker, AR; Petluru, PN; Sridhar, V1
Abdi, SA; Najmi, AK; Raisuddin, S1
Li, G; Yuan, L; Zhuang, Z1
Harvey, JA; Itzhaki, LS; Main, ERG1
Abdi, SAH; Afjal, MA; Najmi, AK; Raisuddin, S1
Cichos, J; Gil, W; Lisowski, M; Stefanowicz, P; Wołczański, G1
Åsberg, A; Bastani, NE; Cox, RD; Dahl, AF; Elshorbagy, A; Olsen, T; Refsum, H; Retterstøl, K; Stolt, E; Vinknes, KJ; Zaré, HK1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1

Reviews

2 review(s) available for cysteine and mesna

ArticleYear
Novel thiols of prokaryotes.
    Annual review of microbiology, 2001, Volume: 55

    Topics: Cysteine; Disaccharides; Ergothioneine; Glutathione; Glycopeptides; Inositol; Mesna; Models, Chemical; Phosphothreonine; Prokaryotic Cells; Pyrazoles; Sulfhydryl Compounds

2001
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Trials

3 trial(s) available for cysteine and mesna

ArticleYear
WR-2721 (amifostine) infusion in patients with Ewing's sarcoma receiving ifosfamide and cyclophosphamide with mesna: drug and thiol levels in plasma and blood cells, a Pediatric Oncology Group study.
    Cancer chemotherapy and pharmacology, 1999, Volume: 44, Issue:6

    Topics: Adolescent; Adult; Amifostine; Antineoplastic Combined Chemotherapy Protocols; Blood Cells; Bone Neoplasms; Child; Cyclophosphamide; Cysteine; Female; Humans; Ifosfamide; Infusions, Intravenous; Kinetics; Male; Mesna; Radiation-Protective Agents; Sarcoma, Ewing; Sulfhydryl Compounds; Time Factors

1999
Intravenous ifosfamide/mesna is associated with depletion of plasma thiols without depletion of leukocyte glutathione.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2000, Volume: 6, Issue:4

    Topics: Acetaldehyde; Antineoplastic Agents, Alkylating; Cysteine; Dose-Response Relationship, Drug; Glutathione; Homocysteine; Humans; Ifosfamide; Infusions, Intravenous; Leukocytes; Mesna; Neoplasms; Oxidation-Reduction; Protective Agents; Sulfhydryl Compounds

2000
Pharmacokinetics and pharmacodynamics of mesna-mediated plasma cysteine depletion.
    Journal of clinical pharmacology, 2003, Volume: 43, Issue:12

    Topics: Antineoplastic Agents, Alkylating; Area Under Curve; Carboplatin; Chromatography, High Pressure Liquid; Cysteine; Female; Half-Life; Humans; Ifosfamide; Male; Mesna; Metabolic Clearance Rate; Middle Aged; Models, Biological; Neoplasms; Protective Agents

2003

Other Studies

33 other study(ies) available for cysteine and mesna

ArticleYear
Influence of sulfide compounds on the metabolism of Methanobacterium strain AZ.
    Archives of microbiology, 1977, Oct-24, Volume: 115, Issue:1

    Topics: Amino Acids; Bacteria; Cysteine; Glutathione; Mesna; Methane; Sulfides

1977
The effects of counter-ion condensation and co-ion depletion upon the rates of chemical repair of poly(U) radicals by thiols.
    International journal of radiation biology, 1991, Volume: 59, Issue:4

    Topics: Cysteamine; Cysteine; Electric Conductivity; Electrons; Glutathione; In Vitro Techniques; Ions; Mercaptoethanol; Mercaptoethylamines; Mesna; Particle Accelerators; Poly U; Pulse Radiolysis; Radiation-Protective Agents; Sulfhydryl Compounds

1991
New mixed disulfides of L-cysteine derivatives and of glutathione with diethyldithiocarbamic acid and 2-mercaptoethanesulfonic acid.
    Arzneimittel-Forschung, 1990, Volume: 40, Issue:3

    Topics: Antineoplastic Agents; Chemical Phenomena; Chemistry; Cysteine; Disulfides; Ditiocarb; Glutathione; Magnetic Resonance Spectroscopy; Mercaptoethanol; Mesna; Molecular Structure

1990
In vitro inhibition of brain glutamic acid decarboxylase by sodium 2-mercaptoethanesulphonate and endogenous thiols and its possible in vivo consequences.
    Human toxicology, 1989, Volume: 8, Issue:3

    Topics: Animals; Blood-Brain Barrier; Brain; Cysteine; Glutamate Decarboxylase; Glutathione; In Vitro Techniques; Male; Mercaptoethanol; Mesna; Rats; Rats, Inbred Strains; Sulfhydryl Compounds

1989
Acetylcholine receptor dimers are stabilized by extracellular disulfide bonding.
    Biochemical and biophysical research communications, 1986, Sep-14, Volume: 139, Issue:2

    Topics: Animals; Cysteine; Disulfides; Mesna; Polymers; Receptors, Cholinergic; Torpedo

1986
Influence of mesna and cysteine on the systemic toxicity and therapeutic efficacy of activated cyclophosphamide.
    Journal of cancer research and clinical oncology, 1987, Volume: 113, Issue:2

    Topics: Animals; Cyclophosphamide; Cysteine; Drug Interactions; Female; Leukemia L1210; Mercaptoethanol; Mesna; Metabolic Clearance Rate; Mice; Platelet Count; Sulfhydryl Compounds

1987
The effect of sodium-2-mercaptoethane-sulphonate, N-acetylcysteine and cysteine on the uptake of cytosine arabinoside by normal and neoplastic thymus cells of mice.
    Archivum immunologiae et therapiae experimentalis, 1988, Volume: 36, Issue:3

    Topics: Acetylcysteine; Animals; Cells, Cultured; Cysteine; Cytarabine; Female; Male; Mercaptoethanol; Mesna; Mice; Thymus Gland; Thymus Neoplasms; Tumor Cells, Cultured

1988
Excretion of sodium 2-mercaptoethanesulphonate (MESNA) in the urine of volunteers after oral dosing.
    European journal of cancer & clinical oncology, 1985, Volume: 21, Issue:5

    Topics: Administration, Oral; Adult; Cysteine; Disulfides; Humans; Male; Mercaptoethanol; Mesna; Sulfhydryl Compounds; Urinary Bladder Diseases

1985
Studies on the toxicity of cyclophosphamide in combination with mesna in vitro and in vivo.
    Cancer treatment reviews, 1983, Volume: 10 Suppl A

    Topics: Animals; Cricetinae; Cricetulus; Cyclophosphamide; Cysteine; Drug Therapy, Combination; Female; Humans; Male; Mercaptoethanol; Mesna; Mice; Mice, Inbred C57BL

1983
The effect of sulfhydryl compounds on 5-fluorouracil toxicity and distribution.
    Archivum immunologiae et therapiae experimentalis, 1983, Volume: 31, Issue:3

    Topics: Animals; Cysteine; Fluorouracil; Glutathione; Kinetics; Lethal Dose 50; Male; Mesna; Mice; Rats; Rats, Inbred Strains; Sulfhydryl Compounds

1983
Cysteine: a potential source of error in amino acid analysis of mercaptoethane sulfonic or hydrochloric acid hydrolysates of proteins and peptides.
    Analytical biochemistry, 1984, Volume: 141, Issue:2

    Topics: Amino Acids; Chemical Phenomena; Chemistry; Cysteine; Glutathione; Hydrochloric Acid; Hydrogen-Ion Concentration; Hydrolysis; Ion Exchange; Mesna; Peptides; Proline; Proteins

1984
[Intracavitary chemotherapy of S 180 ascites sarcoma in mice with 4-(S-ethanol)-sulfido-cyclophosphamide in combination with protector thiols].
    Arzneimittel-Forschung, 1984, Volume: 34, Issue:10

    Topics: Animals; Cyclophosphamide; Cysteine; Drug Therapy, Combination; Female; Kinetics; Mesna; Mice; Sarcoma 180; Sulfhydryl Compounds

1984
2-Mercaptoethanesulfonate-cysteine disulfide excretion following the administration of 2-mercaptoethanesulfonate--a pitfall in the diagnosis of sulfite oxidase deficiency.
    Clinica chimica acta; international journal of clinical chemistry, 1981, Mar-19, Volume: 111, Issue:1

    Topics: Amino Acids; Cysteine; Humans; Infant, Newborn; Kidney; Liver; Mercaptoethanol; Mesna; Oxidoreductases; Oxidoreductases Acting on Sulfur Group Donors; Seizures; Sulfites

1981
Depletion of total cysteine, glutathione, and homocysteine in plasma by ifosfamide/mesna therapy.
    Cancer chemotherapy and pharmacology, 1994, Volume: 35, Issue:2

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Chromatography, High Pressure Liquid; Cysteine; Female; Glutathione; Homeostasis; Homocysteine; Humans; Ifosfamide; Infusions, Intravenous; Male; Mesna; Middle Aged; Sarcoma

1994
Depletion of circulating cyst(e)ine by oral and intravenous mesna.
    British journal of cancer, 1993, Volume: 68, Issue:3

    Topics: Administration, Oral; Adult; Cysteine; Female; Glutathione; Humans; Injections, Intravenous; Male; Mesna; Time Factors

1993
Modulation of plasma thiols and mixed disulfides by BNP7787 in patients receiving paclitaxel/cisplatin therapy.
    Cancer chemotherapy and pharmacology, 2003, Volume: 51, Issue:5

    Topics: Antineoplastic Combined Chemotherapy Protocols; Chromatography, High Pressure Liquid; Cisplatin; Cysteine; Disulfides; Glutathione; Half-Life; Humans; Infusions, Intravenous; Kinetics; Mesna; Neoplasms; Paclitaxel; Sulfhydryl Compounds

2003
Possible (enzymatic) routes and biological sites for metabolic reduction of BNP7787, a new protector against cisplatin-induced side-effects.
    Biochemical pharmacology, 2004, Aug-01, Volume: 68, Issue:3

    Topics: Animals; Antineoplastic Agents; Cisplatin; Cysteine; Cytosol; Electrochemistry; Enzymes; Erythrocytes; Glutathione; Humans; Mesna; Protective Agents; Rats; Tissue Distribution

2004
Mesna or cysteine prevents chloroacetaldehyde-induced cell death of human proximal tubule cells.
    Pediatric nephrology (Berlin, Germany), 2007, Volume: 22, Issue:6

    Topics: Acetaldehyde; Apoptosis; Cell Line; Cysteine; Dose-Response Relationship, Drug; Drug Antagonism; Drug Therapy, Combination; Glutathione; Humans; Kidney Tubules, Proximal; Mesna; Necrosis; Protective Agents

2007
Expressed protein ligation using an N-terminal cysteine containing fragment generated in vivo from a pelB fusion protein.
    Protein expression and purification, 2007, Volume: 54, Issue:2

    Topics: Apolipoproteins; Apolipoproteins E; Cysteine; Inteins; Membrane Proteins; Mesna; Polysaccharide-Lyases; Protein Engineering; Protein Splicing; Recombinant Fusion Proteins; Serine Endopeptidases

2007
Efficient, chemoselective synthesis of immunomicelles using single-domain antibodies with a C-terminal thioester.
    BMC biotechnology, 2009, Jul-20, Volume: 9

    Topics: Antibodies; Cysteine; Escherichia coli; Inteins; Mesna; Micelles; Protein Folding; Recombinant Fusion Proteins

2009
Mechanistic study of BNP7787-mediated cisplatin nephroprotection: modulation of human aminopeptidase N.
    Cancer chemotherapy and pharmacology, 2011, Volume: 67, Issue:2

    Topics: Allosteric Regulation; Biocatalysis; CD13 Antigens; Cisplatin; Cysteine; Dipeptides; Glutathione; Glycine; Humans; Kidney Diseases; Kinetics; Mesna; Models, Biological; Protective Agents; Recombinant Proteins

2011
Chemoselective protein and peptide immobilization on biosensor surfaces.
    Methods in molecular biology (Clifton, N.J.), 2011, Volume: 751

    Topics: 3-Mercaptopropionic Acid; Aldehydes; Amino Acid Sequence; Carboxylic Acids; Cysteine; Immobilized Proteins; Ketones; Mesna; Molecular Sequence Data; Oximes; Peptides; Substrate Specificity; Succinimides; Surface Plasmon Resonance; Surface Properties; Thiazolidines

2011
Cd2+ resistance mechanisms in Methanosarcina acetivorans involve the increase in the coenzyme M content and induction of biofilm synthesis.
    Environmental microbiology reports, 2013, Volume: 5, Issue:6

    Topics: Biofilms; Cadmium; Citrates; Cysteine; DNA, Bacterial; Drug Resistance, Bacterial; Extracellular Matrix; Malates; Mesna; Methane; Methanosarcina; Phosphates; Sulfides

2013
Protein derivitization-expressed protein ligation.
    Methods in enzymology, 2014, Volume: 536

    Topics: Chitin; Cross-Linking Reagents; Cysteine; Esters; Inteins; Mesna; Protein Binding; Recombinant Proteins

2014
Enzymatic and non-enzymatic mechanisms of dimesna metabolism.
    Amino acids, 2015, Volume: 47, Issue:3

    Topics: Animals; Cell Line; Cysteine; Female; Glutathione; Homocysteine; Humans; Kidney; Liver; Mesna; Mice; Oxidation-Reduction

2015
Enhanced electrochemical sensing of thiols based on cobalt phthalocyanine immobilized on nitrogen-doped graphene.
    Biosensors & bioelectronics, 2015, Apr-15, Volume: 66

    Topics: Biosensing Techniques; Cysteine; Electrochemical Techniques; Glutathione; Graphite; Indoles; Limit of Detection; Mesna; Nanocomposites; Nitrogen; Organometallic Compounds; Oxidation-Reduction; Sulfhydryl Compounds

2015
Cysteine specific targeting of the functionally distinct peroxiredoxin and glutaredoxin proteins by the investigational disulfide BNP7787.
    Molecules (Basel, Switzerland), 2015, Mar-18, Volume: 20, Issue:3

    Topics: Antineoplastic Agents; Binding Sites; Crystallography, X-Ray; Cysteine; Glutaredoxins; Homeodomain Proteins; Humans; Mass Spectrometry; Mesna; Models, Molecular; Peroxiredoxins; Protein Structure, Tertiary

2015
Cyclophosphamide-induced Down-Regulation of Uroplakin II in the Mouse Urinary Bladder Epithelium is Prevented by S-Allyl Cysteine.
    Basic & clinical pharmacology & toxicology, 2016, Volume: 119, Issue:6

    Topics: Animals; Antineoplastic Agents; Antineoplastic Agents, Alkylating; Cyclophosphamide; Cysteine; Cystitis; Down-Regulation; Edema; Gene Expression Regulation; Hemorrhage; Mesna; Mice; Organ Size; Protective Agents; Random Allocation; RNA, Messenger; Urinary Bladder; Uroplakin II; Urothelium

2016
Chemical Synthesis of Activity-Based Diubiquitin Probes.
    Methods in molecular biology (Clifton, N.J.), 2017, Volume: 1513

    Topics: Benzene Derivatives; Catalytic Domain; Chemistry Techniques, Synthetic; Cysteine; Deubiquitinating Enzymes; Humans; Mesna; Molecular Probes; Plasmids; Ubiquitin; Ubiquitination

2017
Programmed Protein Self-Assembly Driven by Genetically Encoded Intein-Mediated Native Chemical Ligation.
    ACS synthetic biology, 2018, 04-20, Volume: 7, Issue:4

    Topics: Cysteine; Hydrogen-Ion Concentration; Inteins; Mesna; Nanostructures; Protein Domains; Protein Engineering; Recombinant Fusion Proteins; Temperature; Tetratricopeptide Repeat

2018
S-allyl cysteine ameliorates cyclophosphamide-induced downregulation of urothelial uroplakin IIIa with a concomitant effect on expression and release of CCL11and TNF-α in mice.
    Pharmacological reports : PR, 2018, Volume: 70, Issue:4

    Topics: Animals; Chemokine CCL11; Cyclophosphamide; Cysteine; Cystitis; Down-Regulation; Hemorrhagic Disorders; Male; Mesna; Mice; Protective Agents; Tumor Necrosis Factor-alpha; Urinary Bladder; Uroplakin III

2018
Alkyl Thiocyanurates as Thioester Mimetics. Transthioesterification and Ligation Reactions with High Potential in Dynamic Covalent Chemistry.
    The Journal of organic chemistry, 2023, Jul-07, Volume: 88, Issue:13

    Topics: Cysteine; Glutathione; Mesna; Peptides; Sulfhydryl Compounds

2023
Cysteine-lowering treatment with mesna against obesity: Proof of concept and results from a human phase I, dose-finding study.
    Diabetes, obesity & metabolism, 2023, Volume: 25, Issue:11

    Topics: Animals; Clinical Trials, Phase I as Topic; Cysteine; Humans; Male; Mesna; Mice; Mice, Inbred C3H; Obesity; Overweight

2023