cysteine and melphalan

cysteine has been researched along with melphalan in 13 studies

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-19906 (46.15)18.7374
1990's2 (15.38)18.2507
2000's3 (23.08)29.6817
2010's2 (15.38)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Ahmad, S; Aljian, J; Okine, L; Vistica, DT; Wood, R1
Ahmad, S; Le, B; Najarian, P; Okine, L; Vistica, DT1
Donelli, MG; Garattini, S; Rosso, R1
Dietze, F; Lisewski, G; Reitzig, P; Schulz, HJ1
Ball, CR; Connors, TA1
Fenselau, C; Wu, Z; Yu, X1
Cherian, MG; Imura, N; Satoh, M; Shimizu, H1
Fenselau, C; Szilágyi, Z1
Hulst, AG; Jansen, R; Noort, D1
Colombo, G; Corti, A; Curnis, F; De Mori, GM; Gasparri, A; Longhi, R; Longoni, C; Sacchi, A1
CALCUTT, G; CONNORS, TA; ELSON, LA; ROSS, WC1
Kong, FL; Yang, DJ; Young, DP; Yu, DF; Zhang, Y1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1

Reviews

1 review(s) available for cysteine and melphalan

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Other Studies

12 other study(ies) available for cysteine and melphalan

ArticleYear
gamma-Glutamyl transpeptidase (gamma-GT) and maintenance of thiol pools in tumor cells resistant to alkylating agents.
    Journal of cellular physiology, 1987, Volume: 131, Issue:2

    Topics: Alkylating Agents; Animals; Cell Line; Cysteine; Drug Resistance; Ethylmaleimide; gamma-Glutamyltransferase; Glutamates; Kinetics; Leukemia L1210; Melphalan; Mice; Sulfhydryl Compounds

1987
Elevation of glutathione in phenylalanine mustard-resistant murine L1210 leukemia cells.
    The Journal of biological chemistry, 1987, Nov-05, Volume: 262, Issue:31

    Topics: Animals; Cysteine; Dipeptides; Drug Resistance; Glutathione; Glutathione Disulfide; Kinetics; Leukemia L1210; Melphalan; Mice

1987
On the neurotoxic effects induced by alkylating agents.
    The Journal of pharmacy and pharmacology, 1966, Volume: 18, Issue:11

    Topics: Alanine; Animals; Anti-Bacterial Agents; Antimetabolites; Azaserine; Behavior, Animal; Central Nervous System; Chlorambucil; Cyclophosphamide; Cysteine; Drug Antagonism; Glycine; Male; Mannitol; Mechlorethamine; Melphalan; Nitrogen Mustard Compounds; Phenobarbital; Phenytoin; Rats; Seizures; Spasm; Thiourea; Triethylenemelamine; Tryptophan

1966
[Malabsorption syndrome and intestinal pseudoobstruction in primary vascular and heart amyloidosis].
    Deutsche Zeitschrift fur Verdauungs- und Stoffwechselkrankheiten, 1973, Volume: 33, Issue:4

    Topics: Adult; Amyloidosis; Antibody Formation; Antigen-Antibody Complex; Azathioprine; Chloramphenicol; Cysteine; Heart Diseases; Humans; Intestinal Obstruction; Malabsorption Syndromes; Male; Melphalan; Penicillamine; Prednisone; Time Factors; Vascular Diseases

1973
Reduction of the toxicity of "radiomimetic" alkylating agents by thiol pretreatment. VI. The mechanism of protection by cysteine.
    Biochemical pharmacology, 1967, Volume: 16, Issue:3

    Topics: Alkylation; Animals; Cysteine; Cytoplasm; DNA; Female; Glutathione; Melphalan; Proteins; Rats; RNA; Sarcoma, Yoshida; Thiosulfates; Tritium

1967
Covalent sequestration of melphalan by metallothionein and selective alkylation of cysteines.
    Biochemistry, 1995, Mar-14, Volume: 34, Issue:10

    Topics: Alkylation; Amino Acid Sequence; Animals; Binding Sites; Cysteine; Drug Resistance; Hydrogen-Ion Concentration; In Vitro Techniques; Liver; Melphalan; Metallothionein; Molecular Sequence Data; Molecular Structure; Peptide Fragments; Rabbits; Spectrometry, Mass, Fast Atom Bombardment

1995
Modulation of resistance to anticancer drugs by inhibition of metallothionein synthesis.
    Cancer research, 1994, Oct-15, Volume: 54, Issue:20

    Topics: Alkynes; Animals; Cisplatin; Colonic Neoplasms; Cysteine; Doxorubicin; Drug Resistance; Female; Fibrosarcoma; Glycine; Humans; Male; Melphalan; Metallothionein; Mice; Mice, Inbred BALB C; Mice, Inbred ICR; Mice, Nude; Pargyline; Sulfates; Tumor Cells, Cultured; Urinary Bladder Neoplasms; Zinc Compounds; Zinc Sulfate

1994
Molecular dynamics simulation of metallothionein-drug complexes.
    Drug metabolism and disposition: the biological fate of chemicals, 2000, Volume: 28, Issue:2

    Topics: Binding Sites; Chemical Phenomena; Chemistry, Physical; Chlorambucil; Computer Simulation; Crystallography, X-Ray; Cysteine; Mechlorethamine; Melphalan; Metallothionein; Models, Structural; Nitrogen Mustard Compounds; Protein Binding; Zinc

2000
Covalent binding of nitrogen mustards to the cysteine-34 residue in human serum albumin.
    Archives of toxicology, 2002, Volume: 76, Issue:2

    Topics: Binding Sites; Chlorambucil; Cyclophosphamide; Cysteine; Drug Monitoring; Humans; In Vitro Techniques; Mechlorethamine; Melphalan; Nitrogen Mustard Compounds; Protein Binding; Serum Albumin; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization

2002
Structure-activity relationships of linear and cyclic peptides containing the NGR tumor-homing motif.
    The Journal of biological chemistry, 2002, Dec-06, Volume: 277, Issue:49

    Topics: Amino Acid Motifs; Animals; Arginine; Asparagine; Binding, Competitive; Blotting, Western; Cysteine; Disulfides; Glycine; Humans; Immunohistochemistry; Kinetics; Melphalan; Mice; Mice, Inbred C57BL; Neoplasm Transplantation; Peptides; Protein Binding; Protein Conformation; Protein Structure, Secondary; Protein Structure, Tertiary; Structure-Activity Relationship; Temperature; Time Factors; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha

2002
REDUCTION OF THE TOXICITY OF "RADIOMIMETIC" ALKYLATING AGENTS IN RATS BY THIOL PRETREATMENT. II. MECHANISM OF PROTECTION.
    Biochemical pharmacology, 1963, Volume: 12

    Topics: Alkylating Agents; Cysteine; Melphalan; Nitrogen Mustard Compounds; Pharmacology; Rats; Research; Sulfhydryl Compounds; Toxicology

1963
Development of (99m)Tc-EC-tyrosine for early detection of breast cancer tumor response to the anticancer drug melphalan.
    Academic radiology, 2013, Volume: 20, Issue:1

    Topics: Amino Acid Transport System y+L; Animals; Breast Neoplasms; Chelating Agents; Cysteine; Dose-Response Relationship, Drug; Female; Immunohistochemistry; Ki-67 Antigen; Melphalan; Neoplasm Proteins; Organotechnetium Compounds; Radionuclide Imaging; Rats; Rats, Inbred F344; Tissue Distribution; Treatment Outcome; Tyrosine

2013