cysteine has been researched along with maytansine in 3 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 3 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Baudys, J; Bhakta, S; Ebens, A; Eigenbrot, C; Flagella, KM; Fuji, RN; Hass, PE; Junutula, JR; Kaur, S; Kenrick, M; Khawli, LA; Li, D; Liu, L; Mai, E; McDonald, PJ; Nguyen, T; Parsons-Reponte, KL; Patel, D; Polakis, P; Raab, H; Saad, OM; Scales, SJ; Scheller, RH; Shen, BQ; Sliwkowski, MX; Solis, WA; Spencer, SD; Tibbitts, J; Tien, J; Vandlen, R; Wong, WL; Xu, K; Yu, SF | 1 |
| Liu-Shin, L; Ratnaswamy, G; Wiggins, B; Yamaguchi, H | 1 |
| Ab, O; Bai, C; Erickson, HK; Jin, S; Keating, TA; Lambert, JM; Maloney, EK; McShea, MA; Tavares, D; Wang, L; Whiteman, KR; Widdison, WC; Wilhelm, A; Wilhelm, SD; Yoder, NC | 1 |
3 other study(ies) available for cysteine and maytansine
| Article | Year |
|---|---|
Conjugation site modulates the in vivo stability and therapeutic activity of antibody-drug conjugates.
Topics: Aminobenzoates; Animals; Antibodies; Antibodies, Monoclonal, Humanized; Binding Sites, Antibody; Cell Line, Tumor; Cell Survival; Cysteine; Humans; Immunoconjugates; Immunoglobulin G; Macaca fascicularis; Maleimides; Mammary Neoplasms, Experimental; Maytansine; Mice; Mice, Nude; Models, Molecular; Oligopeptides; Protein Conformation; Protein Engineering; Rats; Structure-Activity Relationship; Sulfhydryl Compounds; Trastuzumab | 2012 |
Characterization of cysteine-linked conjugation profiles of immunoglobulin G1 and immunoglobulin G2 antibody-drug conjugates.
Topics: Ado-Trastuzumab Emtansine; Antibodies, Monoclonal, Humanized; Brentuximab Vedotin; Calorimetry, Differential Scanning; Chemistry, Pharmaceutical; Chromatography, High Pressure Liquid; Chromatography, Reverse-Phase; Cross-Linking Reagents; Cysteine; Drug Stability; Electrophoresis, Capillary; Hydrophobic and Hydrophilic Interactions; Immunoconjugates; Immunoglobulin G; Immunoglobulin Heavy Chains; Immunoglobulin Light Chains; Mass Spectrometry; Maytansine; Oligopeptides; Peptide Mapping; Protein Stability; Technology, Pharmaceutical; Temperature; Trastuzumab | 2015 |
A Case Study Comparing Heterogeneous Lysine- and Site-Specific Cysteine-Conjugated Maytansinoid Antibody-Drug Conjugates (ADCs) Illustrates the Benefits of Lysine Conjugation.
Topics: Animals; Antibodies, Monoclonal; Cell Survival; Cysteine; Female; HeLa Cells; Humans; Immunoconjugates; Injections, Intravenous; Lysine; Maytansine; Mice; Mice, SCID; Treatment Outcome; Tumor Burden; Uterine Cervical Neoplasms; Xenograft Model Antitumor Assays | 2019 |