cysteine has been researched along with leupeptins in 33 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (12.12) | 18.7374 |
| 1990's | 7 (21.21) | 18.2507 |
| 2000's | 15 (45.45) | 29.6817 |
| 2010's | 7 (21.21) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Imahori, K; Ishiura, S; Murofushi, H; Suzuki, K | 1 |
| Mizuno, K; Nakamura, T; Takehara, T | 1 |
| DeMartino, GN; Dick, LR; Moomaw, CR; Pramanik, BC; Slaughter, CA | 1 |
| Abramovitz, AS; Margolis, JW; Wagner, BJ | 1 |
| Fukuyo, T; Hayasaka, S; Mizuno, K | 1 |
| Mego, JL | 1 |
| Leonard, EJ; Skeel, A; Wang, MH; Yoshimura, T | 1 |
| Heilmeyer, LM; Meyer, H; Shoshan-Barmatz, V; Varsanyi, M; Weil, S | 1 |
| Schnellmann, RG; Yang, X | 1 |
| Broekelmann, TJ; Davis, EC; Mecham, RP; Ozawa, Y | 1 |
| Field, MC; Nesbeth, DN; Wainwright, LJ; Wilbourn, B | 1 |
| Feik, D; Hammond, BF; Pham, K; Rams, TE; Whitaker, EJ | 1 |
| Furuta, S; Mason, A; Momand, J; Ortiz, F; Wu, HH; Zhu Sun, X | 1 |
| desBordes, C; Khan, F; Lea, MA; Randolph, VM; Rasheed, M; Shareef, A | 1 |
| Chau, YP; Chen, JH; Lin, SY; Tai, MH | 1 |
| Belbeoc'h, S; Bon, S; Massoulié, J | 1 |
| Beyer, K; Görner, K; Haass, C; Holtorf, E; Kahle, PJ; Nuscher, B; Odoy, S; Regula, JT; Yamamoto, A | 1 |
| Ancuta, P; Gabuzda, D; McPike, M; Mehle, A; Strack, B; Zhang, C | 1 |
| Arulpragasam, A; Butcher, NJ; Minchin, RF | 1 |
| Itoh, K; Kobayashi, A; Kumagai, T; Kusano, Y; Osada, S; Uchida, K; Usami, H; Yamamoto, M | 1 |
| Campbell, RL; Cuerrier, D; Davies, PL; Inoue, J; Moldoveanu, T | 1 |
| Hoshijima, K; Ishikawa, T; Komada, M; Koshiba, S; Nakagawa, H; Tamura, A; Wakabayashi, K | 1 |
| Barrault, L; Bartoli, M; Danos, O; Gicquel, E; Malissen, B; Malissen, M; Perez, N; Richard, I; Soheili, T; Udd, B; Vincent-Lacaze, N | 1 |
| He, M; Kawamura, T; Vanaja, DK; Yin, P; Young, CY | 1 |
| Sarge, KD; Zhang, J | 1 |
| Ang, E; Chai, T; Pavlos, NJ; Qi, M; Ratajczak, T; Rea, SL; Walsh, JP; Xu, J; Zheng, MH | 1 |
| Breitwieser, GE; Cavanaugh, A; McKenna, J; Stepanchick, A | 1 |
| Hayakawa, T; Kawase, N; Kishi, J; Nakamura, H | 1 |
| Castaño, D; Falcon-Perez, JM; Fortian, A; González, E; Millet, O | 1 |
| Endo-Umeda, K; Imai, T; Ishige, K; Ito, Y; Kosuge, Y; Makishima, M; Miyagishi, H | 1 |
| Itoh, K; Liu, T; Maruyama, A; Mimura, J; Ohyama, C; Okada, T; Sato, H; Ye, P | 1 |
| Fadool, DA; Iyer, SR; Schwartz, AB; Vélez, P; Warrington, A | 1 |
| Demizu, Y; Hattori, T; Kurihara, M; Misawa, T; Naito, M; Okitsu, K; Shoda, T | 1 |
33 other study(ies) available for cysteine and leupeptins
| Article | Year |
|---|---|
Studies of a calcium-activated neutral protease from chicken skeletal muscle. I. Purification and characterization.
Topics: Amino Acids; Animals; Calcium; Chickens; Cysteine; Hydrogen-Ion Concentration; Leupeptins; Molecular Weight; Muscles; Peptide Hydrolases; Strontium | 1978 |
Proteolytic activation of a single-chain precursor of hepatocyte growth factor by extracellular serine-protease.
Topics: Animals; Autoradiography; Cell Division; Cell Line; CHO Cells; Cricetinae; Cysteine; DNA; Electrophoresis, Polyacrylamide Gel; Fibrinolysin; Hepatocyte Growth Factor; Humans; Leupeptins; Liver; Lung; Methionine; Plasmids; Protein Precursors; Protein Processing, Post-Translational; Rats; Recombinant Proteins; Serine Endopeptidases; Sulfur Radioisotopes; Tissue Plasminogen Activator; Transfection; Urokinase-Type Plasminogen Activator | 1992 |
Identification and localization of a cysteinyl residue critical for the trypsin-like catalytic activity of the proteasome.
Topics: Amino Acid Sequence; Animals; Binding Sites; Cattle; Chromatography, High Pressure Liquid; Chromatography, Ion Exchange; Chymotrypsin; Cyanogen Bromide; Cysteine; Cysteine Endopeptidases; Erythrocytes; Ethylmaleimide; Humans; Kinetics; Leupeptins; Macromolecular Substances; Molecular Sequence Data; Multienzyme Complexes; Myocardium; Peptide Fragments; Peptide Mapping; Proteasome Endopeptidase Complex; Trypsin | 1992 |
The bovine lens neutral proteinase comprises a family of cysteine-dependent proteolytic activities.
Topics: Animals; Cattle; Cysteine; Endopeptidases; Hydrolysis; Lens, Crystalline; Leupeptins; Neprilysin; Nitrobenzenes; Oligopeptides; Peptide Hydrolases; Protease Inhibitors; Substrate Specificity; Trypsin | 1986 |
Acidic lens protein degrading activity in bovine ciliary body.
Topics: Animals; Cattle; Chromatography; Ciliary Body; Crystallins; Cysteine; Hydrogen-Ion Concentration; Leupeptins; Pepstatins; Protease Inhibitors | 1985 |
Role of thiols, pH and cathepsin D in the lysosomal catabolism of serum albumin.
Topics: Animals; Cathepsin D; Cathepsins; Cysteine; Glutathione; Hydrogen-Ion Concentration; In Vitro Techniques; Iodoacetamide; Kidney; Leupeptins; Liver; Lysosomes; Mice; Pepstatins; Rats; Rats, Inbred Strains; Serum Albumin, Bovine; Sulfhydryl Compounds | 1984 |
Proteolytic conversion of single chain precursor macrophage-stimulating protein to a biologically active heterodimer by contact enzymes of the coagulation cascade.
Topics: Animals; Aprotinin; Blood Coagulation Factors; Cells, Cultured; Chemotaxis; CHO Cells; Cloning, Molecular; Cricetinae; Cysteine; Enzyme-Linked Immunosorbent Assay; Factor XIa; Factor XIIa; Growth Substances; Hepatocyte Growth Factor; Humans; Kallikreins; Kinetics; Leupeptins; Macromolecular Substances; Macrophages; Mice; Molecular Weight; Protein Precursors; Protein Processing, Post-Translational; Proto-Oncogene Proteins; Recombinant Proteins; Serine Proteinase Inhibitors; Transfection | 1994 |
Endogenous, Ca(2+)-dependent cysteine-protease cleaves specifically the ryanodine receptor/Ca2+ release channel in skeletal muscle.
Topics: Adenosine Triphosphate; Amino Acid Sequence; Animals; Calcium; Calcium Channels; Calpain; Cysteine; Dithiothreitol; Iodoacetamide; Leupeptins; Magnesium; Mercaptoethanol; Mercuric Chloride; Molecular Sequence Data; Molecular Weight; Muscle Proteins; Muscle, Skeletal; Rabbits; Ryanodine Receptor Calcium Release Channel; Sarcoplasmic Reticulum; Sodium Chloride; Substrate Specificity | 1994 |
Proteinases in renal cell death.
Topics: Animals; Anti-Bacterial Agents; Antimycin A; Antipain; Carboxypeptidases; Cathepsin A; Cathepsin B; Cell Death; Coumarins; Cysteine; Cysteine Proteinase Inhibitors; Dose-Response Relationship, Drug; Endopeptidases; Hydrocarbons, Fluorinated; Hydroquinones; Isocoumarins; Kidney Tubules, Proximal; L-Lactate Dehydrogenase; Leucine; Leupeptins; Lysosomes; Membrane Potentials; Pepstatins; Peroxides; Rabbits; Reactive Oxygen Species; Serine Proteinase Inhibitors; tert-Butylhydroperoxide; Tosyllysine Chloromethyl Ketone | 1996 |
Identification of tropoelastin as a ligand for the 65-kD FK506-binding protein, FKBP65, in the secretory pathway.
Topics: Amino Acid Isomerases; Animals; Brefeldin A; Carrier Proteins; Cattle; Cell Compartmentation; Centrifugation, Density Gradient; Cyclopentanes; Cysteine; DNA-Binding Proteins; Heat-Shock Proteins; Leupeptins; Ligands; Methionine; Molecular Weight; Protein Folding; Protein Synthesis Inhibitors; Tacrolimus; Tacrolimus Binding Proteins; Tropoelastin | 1998 |
Proteasome and thiol involvement in quality control of glycosylphosphatidylinositol anchor addition.
Topics: Acetylcysteine; Animals; CHO Cells; Cricetinae; Cysteine; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Endoplasmic Reticulum; Glycosylphosphatidylinositols; Human Growth Hormone; Humans; Leupeptins; Multienzyme Complexes; Mutation; Peptides; Proteasome Endopeptidase Complex; Recombinant Fusion Proteins; Sulfhydryl Compounds; Ubiquitins | 1998 |
Aggregation of human platelets by gingipain-R from Porphyromonas gingivalis cells and membrane vesicles.
Topics: Adhesins, Bacterial; Antithrombin III; Arginine; Blood Platelets; Cell Membrane; Chromatography; Cysteine; Cysteine Endopeptidases; Gingipain Cysteine Endopeptidases; Hemagglutinins; Humans; Leupeptins; Platelet Aggregation; Porphyromonas gingivalis | 2002 |
Copper uptake is required for pyrrolidine dithiocarbamate-mediated oxidation and protein level increase of p53 in cells.
Topics: Animals; Antioxidants; Breast Neoplasms; Cells, Cultured; Chelating Agents; Copper; Cysteine; Cysteine Proteinase Inhibitors; Ditiocarb; Female; Fibroblasts; Free Radicals; Humans; Hydrogen Peroxide; Leupeptins; Mannitol; Molecular Structure; Oxidants; Oxidation-Reduction; Pyrrolidines; Rats; Recombinant Proteins; Thiobarbituric Acid Reactive Substances; Thiocarbamates; Tumor Suppressor Protein p53 | 2002 |
Induction of histone acetylation and inhibition of growth of mouse erythroleukemia cells by S-allylmercaptocysteine.
Topics: Acetylation; Acetyltransferases; Allyl Compounds; Animals; Antineoplastic Agents; Breast Neoplasms; Colonic Neoplasms; Cysteine; Disulfides; Electrophoresis, Polyacrylamide Gel; Female; Histone Acetyltransferases; Histone Deacetylases; Histones; Humans; Leukemia, Erythroblastic, Acute; Leupeptins; Mice; Saccharomyces cerevisiae Proteins; Sulfinic Acids; Tumor Cells, Cultured | 2002 |
Endostatin induces autophagic cell death in EAhy926 human endothelial cells.
Topics: Acridine Orange; Adenine; Animals; Antineoplastic Agents; Apoptosis; Aprotinin; Blotting, Western; Caspases; Cell Death; Cells, Cultured; CHO Cells; Cloning, Molecular; Cricetinae; Cysteine; Cysteine Endopeptidases; Dose-Response Relationship, Drug; Endostatins; Endothelial Cells; Endothelium, Vascular; Enzyme Activation; Flow Cytometry; Glutathione Transferase; Humans; Immunohistochemistry; Leupeptins; Lysosomes; Microscopy, Electron; Microscopy, Phase-Contrast; Oxidative Stress; Reactive Oxygen Species; Recombinant Proteins; Serine; Time Factors | 2003 |
The C-terminal T peptide of acetylcholinesterase enhances degradation of unassembled active subunits through the ERAD pathway.
Topics: Acetylcholinesterase; Alkaline Phosphatase; Amino Acid Sequence; Amino Acid Substitution; Amino Acids, Aromatic; Animals; Chlorocebus aethiops; Conserved Sequence; COS Cells; Cysteine; Dimerization; Endoplasmic Reticulum; Humans; Lactones; Leupeptins; Molecular Sequence Data; Nippostrongylus; Peptides; Protein Subunits; Rats; Serine | 2003 |
Differential effects of Parkinson's disease-associated mutations on stability and folding of DJ-1.
Topics: Cell Line; Circular Dichroism; Cycloheximide; Cysteine; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Enzyme Inhibitors; Escherichia coli; Gene Deletion; Humans; Intracellular Signaling Peptides and Proteins; Leupeptins; Mass Spectrometry; Multienzyme Complexes; Mutagenesis, Site-Directed; Mutation; Neurons; Oncogene Proteins; Parkinson Disease; Point Mutation; Proteasome Endopeptidase Complex; Protein Conformation; Protein Deglycase DJ-1; Protein Folding; Protein Structure, Secondary; Protein Synthesis Inhibitors; Reverse Transcriptase Polymerase Chain Reaction; Temperature; Time Factors | 2004 |
Vif overcomes the innate antiviral activity of APOBEC3G by promoting its degradation in the ubiquitin-proteasome pathway.
Topics: APOBEC-3G Deaminase; Cell Line; Cell Line, Tumor; Conserved Sequence; Cysteine; Cysteine Endopeptidases; Cytidine Deaminase; Drug Interactions; Enzyme Inhibitors; Gene Deletion; Gene Expression; Gene Products, vif; Half-Life; HIV-1; Humans; Immunosorbent Techniques; Lactones; Leupeptins; Multienzyme Complexes; Mutation; Nucleoside Deaminases; Phosphorylation; Proteasome Endopeptidase Complex; Proteins; Recombinant Proteins; Repressor Proteins; Reverse Transcriptase Polymerase Chain Reaction; Structure-Activity Relationship; Transfection; Ubiquitin; vif Gene Products, Human Immunodeficiency Virus | 2004 |
Proteasomal degradation of N-acetyltransferase 1 is prevented by acetylation of the active site cysteine: a mechanism for the slow acetylator phenotype and substrate-dependent down-regulation.
Topics: 4-Aminobenzoic Acid; Alleles; Arylamine N-Acetyltransferase; Binding Sites; Blotting, Western; Cell Line, Tumor; Cloning, Molecular; Cycloheximide; Cysteine; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; DNA, Complementary; Down-Regulation; Escherichia coli; Genotype; Glutathione Transferase; Humans; Isoenzymes; Leukocytes, Mononuclear; Leupeptins; Models, Biological; Multienzyme Complexes; Mutagenesis, Site-Directed; Mutation; Oxidative Stress; Peptide Hydrolases; Phenotype; Precipitin Tests; Proteasome Endopeptidase Complex; Protein Binding; Protein Synthesis Inhibitors; Recombinant Proteins; Time Factors; Ubiquitin | 2004 |
Selective induction of the tumor marker glutathione S-transferase P1 by proteasome inhibitors.
Topics: Acetylcysteine; Animals; Biomarkers, Tumor; Blotting, Western; Cysteine; DNA-Binding Proteins; DNA, Complementary; Down-Regulation; Enzyme Inhibitors; Epithelial Cells; Genes, Dominant; Glutathione S-Transferase pi; Glutathione Transferase; Intracellular Signaling Peptides and Proteins; Isoenzymes; Kelch-Like ECH-Associated Protein 1; Lactones; Leupeptins; Luciferases; Mice; NF-E2-Related Factor 2; Oligonucleotides, Antisense; Promoter Regions, Genetic; Proteasome Endopeptidase Complex; Proteasome Inhibitors; Protein Isoforms; Protein Structure, Tertiary; Proteins; Rats; Reverse Transcriptase Polymerase Chain Reaction; RNA Interference; RNA, Small Interfering; Time Factors; Trans-Activators; Transfection; Up-Regulation | 2005 |
Calpain inhibition by alpha-ketoamide and cyclic hemiacetal inhibitors revealed by X-ray crystallography.
Topics: Amino Acid Sequence; Animals; Binding Sites; Calpain; Catalytic Domain; Conserved Sequence; Crystallography, X-Ray; Cysteine; Hydrogen Bonding; Hydrogen-Ion Concentration; Isoenzymes; Leupeptins; Models, Molecular; Molecular Conformation; Molecular Sequence Data; Molecular Structure; Protease Inhibitors; Protein Conformation; Protein Structure, Secondary; Protein Structure, Tertiary; Rats; Sequence Homology, Amino Acid; Solutions; Water | 2006 |
Intramolecular disulfide bond is a critical check point determining degradative fates of ATP-binding cassette (ABC) transporter ABCG2 protein.
Topics: Adenosine Triphosphate; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Cell Line; Cysteine; Dimerization; Disulfides; Dose-Response Relationship, Drug; Humans; Leupeptins; Lysosomes; Neoplasm Proteins; Proteasome Endopeptidase Complex; Proteasome Inhibitors; Protein Binding; Protein Denaturation; Ubiquitin; Xenobiotics | 2007 |
Mannosidase I inhibition rescues the human alpha-sarcoglycan R77C recurrent mutation.
Topics: Alkaloids; Animals; Cell Line, Tumor; Cysteine; Female; Humans; Leupeptins; Mannosidases; Mice; Mice, Knockout; Muscles; Muscular Dystrophies, Limb-Girdle; Muscular Dystrophy, Animal; Mutation, Missense; Phenotype; Protein Transport; Sarcoglycans | 2008 |
Phenethyl isothiocyanate induces cell cycle arrest and reduction of alpha- and beta-tubulin isotypes in human prostate cancer cells.
Topics: Anticarcinogenic Agents; Antioxidants; Blotting, Western; Cell Cycle; Cell Line, Tumor; Cysteine; Flow Cytometry; G2 Phase; Humans; Isothiocyanates; Leupeptins; Male; Prostatic Neoplasms; Protein Isoforms; Tubulin | 2009 |
Identification of a polymorphism in the RING finger of human Bmi-1 that causes its degradation by the ubiquitin-proteasome system.
Topics: Amino Acid Sequence; Cells, Cultured; Cysteine; Cysteine Proteinase Inhibitors; Humans; Leupeptins; Nuclear Proteins; Polycomb Repressive Complex 1; Polymorphism, Single Nucleotide; Proteasome Endopeptidase Complex; Protein Denaturation; Protein Processing, Post-Translational; Proto-Oncogene Proteins; Repressor Proteins; RING Finger Domains; Transfection; Tyrosine; Ubiquitin | 2009 |
Proteasome inhibitors impair RANKL-induced NF-kappaB activity in osteoclast-like cells via disruption of p62, TRAF6, CYLD, and IkappaBalpha signaling cascades.
Topics: Actins; Animals; Bone Resorption; Cell Line; Cysteine; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Deubiquitinating Enzyme CYLD; Erythropoietin; Humans; I-kappa B Proteins; Leupeptins; Mice; Mice, Inbred C57BL; Microtubules; NF-kappa B; NF-KappaB Inhibitor alpha; Oligopeptides; Osteoclasts; Proteasome Endopeptidase Complex; Proteasome Inhibitors; RANK Ligand; Signal Transduction; Synaptotagmin I; TNF Receptor-Associated Factor 6; Transcription Factor TFIIH; Transcription Factors | 2009 |
Calcium-sensing receptor biosynthesis includes a cotranslational conformational checkpoint and endoplasmic reticulum retention.
Topics: Aniline Compounds; Blotting, Western; Calcium; Cell Line; Cell Membrane; Cysteine; Cysteine Proteinase Inhibitors; Endoplasmic Reticulum; Green Fluorescent Proteins; Humans; Leupeptins; Mutant Proteins; Mutation; Neomycin; Phenethylamines; Propylamines; Protein Biosynthesis; Protein Conformation; Protein Transport; Receptors, Calcium-Sensing; Recombinant Fusion Proteins; Sulfur Radioisotopes; Time Factors; Transfection | 2010 |
Collagenolytic activity in sonic extracts of Tannerella forsythia.
Topics: Bacteroides; Calcium Chloride; Cathepsins; Cell Line, Tumor; Chelating Agents; Collagen Type I; Cysteine; Cysteine Proteinase Inhibitors; Edetic Acid; Electrophoresis, Polyacrylamide Gel; Enzyme Activation; Enzyme Inhibitors; Enzyme Precursors; Ethylmaleimide; Gelatinases; Humans; Iodoacetamide; Iodoacetic Acid; Leucine; Leupeptins; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Phenylmethylsulfonyl Fluoride; Protease Inhibitors; Serine Proteinase Inhibitors; Tosyllysine Chloromethyl Ketone; Tosylphenylalanyl Chloromethyl Ketone | 2010 |
Intracellular rescue of the uroporphyrinogen III synthase activity in enzymes carrying the hotspot mutation C73R.
Topics: Amino Acid Substitution; Catalysis; Cell Line; Cysteine; Cysteine Proteinase Inhibitors; Enzyme Stability; Humans; Leupeptins; Mutation, Missense; Porphyria, Erythropoietic; Proteasome Endopeptidase Complex; Proteasome Inhibitors; Uroporphyrinogen III Synthetase | 2011 |
Protective effect of S-allyl-L-cysteine against endoplasmic reticulum stress-induced neuronal death is mediated by inhibition of calpain.
Topics: Animals; Apoptosis; Calcium-Binding Proteins; Calpain; Cell Survival; Cells, Cultured; Cysteine; Dipeptides; Endoplasmic Reticulum Stress; Hippocampus; Leupeptins; Neurons; Neuroprotective Agents; Oxidative Stress; Rats; Rats, Wistar; Spectrin | 2014 |
Nrf2- and ATF4-dependent upregulation of xCT modulates the sensitivity of T24 bladder carcinoma cells to proteasome inhibition.
Topics: Activating Transcription Factor 4; Amino Acid Transport System y+; Antineoplastic Agents; Boronic Acids; Bortezomib; Cell Line, Tumor; Cysteine; Gene Expression Regulation, Neoplastic; Gene Knockdown Techniques; Glutathione; Glycine; HEK293 Cells; HeLa Cells; Humans; Leupeptins; NF-E2-Related Factor 2; Oligopeptides; Proteasome Endopeptidase Complex; Pyrazines; RNA, Small Interfering; Sulfasalazine; Urinary Bladder Neoplasms | 2014 |
Ubiquitin ligase Nedd4-2 modulates Kv1.3 current amplitude and ion channel protein targeting.
Topics: Animals; Antibodies; Cell Line, Transformed; Cysteine; Cysteine Proteinase Inhibitors; Down-Regulation; Electric Stimulation; Endosomal Sorting Complexes Required for Transport; Gene Expression Regulation; GRB10 Adaptor Protein; HEK293 Cells; Humans; Kv1.3 Potassium Channel; Leupeptins; Lysine; Membrane Potentials; Models, Biological; Mutation; Nedd4 Ubiquitin Protein Ligases; Patch-Clamp Techniques; RNA-Binding Protein FUS; Ubiquitin-Protein Ligases; Ubiquitination | 2016 |
Development of a Small Hybrid Molecule That Mediates Degradation of His-Tag Fused Proteins.
Topics: Biotin; Cell Line; Cysteine; Histidine; Humans; Leupeptins; Maleimides; Nitrilotriacetic Acid; Organometallic Compounds; Proteasome Inhibitors; Proteolysis; Receptors, Retinoic Acid; Recombinant Fusion Proteins; Smad2 Protein; Ubiquitin-Protein Ligases | 2018 |