cysteine and leukotriene d4

cysteine has been researched along with leukotriene d4 in 52 studies

Research

Studies (52)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's10 (19.23)18.2507
2000's31 (59.62)29.6817
2010's9 (17.31)24.3611
2020's2 (3.85)2.80

Authors

AuthorsStudies
Abram, TS; Brink, C; Cuthbert, NJ; Gardiner, PJ; Norman, P; Tudhope, SR1
Horiba, M; Kohno, S; Nabe, T; Ohata, K; Saeki, Y; Tanpo, T; Yamamura, H1
Gareau, Y; Lord, A; Metters, KM; Rochette, C; Sawyer, N1
Broughton, KS; Dietert, RR; Golemboski, KA; Kinsella, JE; Whelan, J1
Boeker, DK; Deinsberger, W; Joedicke, A; Müller, HW; Winking, M1
Ohrui, T; Okinaga, S; Sasaki, H; Sekizawa, K; Terajima, M; Yamaya, M1
Cuevas, AA; Guo, Q; Habib, GM; Lieberman, MW; Matzuk, MM; Shi, ZZ1
Jonsson, EW1
Khawaja, AM; Liu, YC; Rogers, DF1
Carter, BZ; Lieberman, MW; Reed, DJ; Shields, JE; Will, Y1
Abramovitz, M; Austin, CP; Bellefeuille, JN; Cheng, R; Clements, MK; Coulombe, N; Evans, JF; Figueroa, DJ; George, SR; Heise, CE; Im, DS; Liu, Q; Liu, Y; Lynch, KR; Ma, L; Metters, KM; Nguyen, T; O'Dowd, BF; O'Neill, GP; Sawyer, N; Stocco, R; Williams, DL; Zeng, Z1
Bäck, M; Brink, C; Dahlén, S; Gascard, J; Mazmanian, G; Norel, X; Walch, L1
Bäck, M; Brink, C; Dahlén, S; de Montpreville, V; Gascard, J; Norel, X; Walch, L1
Arroyo, V; Bataller, R; Bosch-Marcé, M; Clària, J; Ginès, P; Jiménez, W; Rivera, F; Rodés, J; Titos, E1
Abe, M; Hugli, TE; Kamiya, H; Katsuragi, T; Kodani, M; Sakata, N; Takano, Y1
Bäck, M; Cotgreave, IA; Dahlén, SE; Kumlin, M1
Akagi, M; Fukuishi, N; Fukuyama, Y; Takada, T1
Bandeira-Melo, C; Hall, JC; Penrose, JF; Weller, PF1
Bäck, M1
Fujisawa, T; Hirai, K; Kishikawa, K; Koshino, T; Miyamasu, M; Morita, Y; Nagase, H; Nakagawa, N; Ohshima, N; Yamaguchi, M; Yamamoto, K1
Buchholz, U; Fukui, H; Imazu, H; Keppler, D; Kikuchi, E; Kikukawa, M; Kojima, H; Matsumoto, M; Tsujii, T; Uemura, M1
Gopalakrishnan, V; Liu, P; Misurski, DA1
Crimi, N; Mastruzzo, C; Pagano, C; Palermo, F; Pistorio, MP; Prosperini, G; Vancheri, C1
Alving, K; Kumlin, M; Sylvin, H1
Andersen, L; Bouchelouche, K; Bouchelouche, P; Horn, T; Nordling, J1
Fukushima, C; Kawano, T; Kohno, S; Kondo, Y; Machida, I; Matsuse, H; Mitsuta, K; Obase, Y; Saeki, S; Shimoda, T; Tomari, S1
Dahlén, SE; Låstbom, L; Ryrfeldt, A; Sundström, E1
Berghaus, LJ; Berghaus, RD; Decile, KC; Gershwin, LJ; Hyde, DM; Norris, CR; Schelegle, ES; Walby, WF1
Accomazzo, MR; Capra, V; Parenti, M; Ravasi, S; Rovati, GE1
Redfors, S; Reims, A; Sjövall, H; Strandvik, B1
Balduino, A; Barreiro, EJ; Diaz, BL; e Silva, PM; Fraga, CA; Lima, LM; Martins, MA; Miranda, AL; Neves, JS; Siqueira, Rde A1
Bureau, F; Hemelaers, L; Henket, M; Louis, R; Sele, J1
Rola-Pleszczynski, M; Stankova, J; Thivierge, M1
Baroffio, M; Brichetto, L; Brusasco, V; Citro, S; Crimi, E; Milanese, M; Ravasi, S; Rovati, GE1
Bacskai, BJ; Borrelli, LA; Boyce, JA; Jiang, Y; Kanaoka, Y1
Chen, LY; Nagineni, S; Shelhamer, JH; Woszczek, G1
Hamid, Q; Hassan, M; Jo, T; Martin, JG; McGovern, T; Ramos-Barbón, D; Tamaoka, M; Tolloczko, B; Yoshizawa, Y1
Backman, L; Baumforth, KR; Björkholm, M; Claesson, HE; Malec, M; Murray, PG; Porwit, A; Schain, F; Sjöberg, J; Tryselius, Y; Vockerodt, M; Wei, W; Xu, D1
Ikeda, Y; Imbe, S; Iwanaga, T; Muraki, M; Sato, R; Tohda, Y; Yamagata, S1
Kim, SH; Park, HS; Yang, EM1
Farias, S; Frey, LC; Heidenreich, KA; Murphy, RC1
Hunter, JC; Jia, Y; Jimenez, J; Lieber, G; McLeod, RL1
Chiba, Y; Enzaka, J; Misawa, M; Sakai, H; Sakai-Oshita, M1
Cai, BL; Fang, SH; Huang, XQ; Lu, YB; Wang, XX; Wei, EQ; Yu, SY; Zhang, WP; Zhang, XY1
Boehmler, A; Drost, AC; Funk, M; Kanz, L; Möhle, R; Norz, KP; Seitz, G; Xue, X; Zipfel, A1
Diener, M; Rehn, M1
Bowen, H; Cousins, DJ; Fuerst, E; Lee, TH; McDonald, J; Parmentier, CN; Pease, JE; Woszczek, G1
Chakir, J; Chouinard, F; Flamand, N; Langlois, A; Laviolette, M; Provost, V; Rola-Pleszczynski, M1
Celik, D; Celikel, S; Doruk, S; Erkorkmaz, U; Koseoglu, HI; Sahin, S1
Ferrer, R; Moreno, JJ; Rodríguez-Lagunas, MJ; Storniolo, CE1
Al-Azzam, N; Elsalem, L1
Barrett, NA; Boyce, JA; Feng, C; Lai, J; Liu, T; Nagai, J1

Reviews

4 review(s) available for cysteine and leukotriene d4

ArticleYear
Leukotriene receptors and their selective antagonists.
    Advances in prostaglandin, thromboxane, and leukotriene research, 1994, Volume: 22

    Topics: Animals; Cysteine; Humans; Leukotriene Antagonists; Leukotriene C4; Leukotriene D4; Lung; Receptors, Leukotriene; SRS-A

1994
Functional characterisation of receptors for cysteinyl leukotrienes in smooth muscle.
    Acta physiologica Scandinavica. Supplementum, 1998, Volume: 641

    Topics: Animals; Cysteine; Guinea Pigs; Humans; Ileum; In Vitro Techniques; Leukotriene Antagonists; Leukotriene C4; Leukotriene D4; Leukotriene E4; Leukotrienes; Lung; Muscle, Smooth; Receptors, Leukotriene

1998
Functional characteristics of cysteinyl-leukotriene receptor subtypes.
    Life sciences, 2002, Jun-28, Volume: 71, Issue:6

    Topics: Animals; Asthma; Blood Vessels; Cysteine; Humans; Inflammation Mediators; Leukotriene D4; Leukotrienes; Membrane Proteins; Receptors, Leukotriene; Vasoconstriction; Vasoconstrictor Agents

2002
Leukotriene D
    Life sciences, 2020, Nov-01, Volume: 260

    Topics: Acetates; Airway Remodeling; Animals; Anti-Asthmatic Agents; Asthma; Bronchial Hyperreactivity; Cyclopropanes; Cysteine; Gene Expression; Humans; Hypersensitivity; Indoles; Inflammation Mediators; Leukotriene Antagonists; Leukotriene D4; Leukotrienes; Phenylcarbamates; Quinolines; Receptors, Leukotriene; Sulfides; Sulfonamides; Tosyl Compounds

2020

Trials

1 trial(s) available for cysteine and leukotriene d4

ArticleYear
Inhibitory effect of a leukotriene receptor antagonist (montelukast) on neurokinin A-induced bronchoconstriction.
    The Journal of allergy and clinical immunology, 2003, Volume: 111, Issue:4

    Topics: Acetates; Adult; Bronchoconstriction; Cross-Over Studies; Cyclopropanes; Cysteine; Double-Blind Method; Female; Forced Expiratory Volume; Humans; Leukotriene Antagonists; Leukotriene D4; Leukotrienes; Male; Methacholine Chloride; Neurokinin A; Quinolines; Sulfides

2003

Other Studies

47 other study(ies) available for cysteine and leukotriene d4

ArticleYear
Inhibitory effect of ONO-1078 on specific binding of peptide leukotrienes to human lung crude membrane.
    Prostaglandins, leukotrienes, and essential fatty acids, 1994, Volume: 51, Issue:3

    Topics: Cell Membrane; Chromones; Cysteine; gamma-Glutamyltransferase; Glycine; Humans; Isoxazoles; Leukotriene D4; Lung; Protein Binding; SRS-A

1994
Characterization of specific binding sites for cysteinyl leukotrienes in sheep lung.
    The Journal of pharmacology and experimental therapeutics, 1994, Volume: 270, Issue:1

    Topics: Animals; Binding Sites; Binding, Competitive; Cations, Divalent; Cysteine; In Vitro Techniques; Kinetics; Leukotriene Antagonists; Leukotriene D4; Leukotrienes; Lung; Membrane Proteins; Membranes; Nucleotides; Radioligand Assay; Receptors, Leukotriene; Sheep; Substrate Specificity; Tritium

1994
Characterization of leukotriene production in vivo and in vitro in resident and elicited peritoneal macrophages in chickens and mice.
    Prostaglandins, leukotrienes, and essential fatty acids, 1997, Volume: 56, Issue:1

    Topics: Animals; Calcimycin; Chickens; Cysteine; Dextrans; Ionophores; Kinetics; Leukotriene C4; Leukotriene D4; Leukotriene E4; Leukotrienes; Macrophage Activation; Macrophages, Peritoneal; Male; Mice; Mice, Inbred Strains; Zymosan

1997
Levels of immunoreactive cysteinyl-leukotrienes in CSF after subarachnoid haemorrhage correlate with blood flow-velocity in TCD.
    Acta neurochirurgica, 1997, Volume: 139, Issue:8

    Topics: Adult; Aneurysm, Ruptured; Blood Flow Velocity; Brain; Chromatography, High Pressure Liquid; Cysteine; Enzyme-Linked Immunosorbent Assay; Female; Humans; Intracranial Aneurysm; Leukotriene C4; Leukotriene D4; Leukotriene E4; Leukotrienes; Male; Middle Aged; Postoperative Complications; Subarachnoid Hemorrhage; Ultrasonography, Doppler, Transcranial

1997
Dipeptidase inhibitor and epithelial removal potentiate leukotriene D4-induced human tracheal smooth muscle contraction.
    Respiration physiology, 1998, Volume: 111, Issue:1

    Topics: Acetylcholine; Adult; Aged; Aged, 80 and over; Cells, Cultured; Cilastatin; Cysteine; Dipeptidases; Drug Synergism; Epithelium; GPI-Linked Proteins; Humans; In Vitro Techniques; Leukotriene D4; Middle Aged; Muscle Contraction; Muscle, Smooth; Protease Inhibitors; Trachea

1998
Leukotriene D4 and cystinyl-bis-glycine metabolism in membrane-bound dipeptidase-deficient mice.
    Proceedings of the National Academy of Sciences of the United States of America, 1998, Apr-28, Volume: 95, Issue:9

    Topics: Animals; Cysteine; Dipeptidases; Glutathione; Glycine; Lactams; Leukotriene D4; Mice; Mice, Knockout; Oligopeptides

1998
Effects of the cysteinyl leukotriene receptor antagonists pranlukast and zafirlukast on tracheal mucus secretion in ovalbumin-sensitized guinea-pigs in vitro.
    British journal of pharmacology, 1998, Volume: 124, Issue:3

    Topics: Adenosine Triphosphate; Animals; Anti-Asthmatic Agents; Binding, Competitive; Chromones; Cysteine; Guinea Pigs; Hypersensitivity; In Vitro Techniques; Indoles; Leukotriene Antagonists; Leukotriene D4; Male; Membrane Proteins; Mucus; Ovalbumin; Passive Cutaneous Anaphylaxis; Phenylcarbamates; Receptors, Leukotriene; Sulfates; Sulfonamides; Sulfur Radioisotopes; Tosyl Compounds; Trachea

1998
Gamma-glutamyl leukotrienase cleavage of leukotriene C4.
    Advances in experimental medicine and biology, 1999, Volume: 469

    Topics: Animals; Cysteine; Dipeptidases; gamma-Glutamyltransferase; Glutathione; Kinetics; Leukotriene C4; Leukotriene D4; Liver; Lung; Mice; Mice, Knockout; Spleen; Substrate Specificity

1999
Characterization of the human cysteinyl leukotriene 2 receptor.
    The Journal of biological chemistry, 2000, Sep-29, Volume: 275, Issue:39

    Topics: Adrenal Medulla; Cloning, Molecular; Cysteine; Humans; Leukotriene Antagonists; Leukotriene C4; Leukotriene D4; Leukotriene E4; Leukotrienes; Lung; Membrane Proteins; Models, Molecular; Myocardium; Receptors, Leukotriene; Recombinant Proteins; Sequence Analysis, DNA; Sequence Homology, Amino Acid; SRS-A; Tissue Distribution

2000
Antagonist resistant contractions of the porcine pulmonary artery by cysteinyl-leukotrienes.
    European journal of pharmacology, 2000, Aug-11, Volume: 401, Issue:3

    Topics: 6-Ketoprostaglandin F1 alpha; Animals; Cysteine; Dose-Response Relationship, Drug; Endothelium, Vascular; In Vitro Techniques; Indoles; Indomethacin; Leukotriene Antagonists; Leukotriene C4; Leukotriene D4; Leukotriene E4; Leukotrienes; Male; Membrane Proteins; Phenylcarbamates; Pulmonary Artery; Receptors, Leukotriene; SRS-A; Sulfonamides; Swine; Thromboxane A2; Tosyl Compounds; Vasoconstriction

2000
Prostacyclin modulation of contractions of the human pulmonary artery by cysteinyl-leukotrienes.
    European journal of pharmacology, 2000, Aug-11, Volume: 401, Issue:3

    Topics: 6-Ketoprostaglandin F1 alpha; Cysteine; Dose-Response Relationship, Drug; Endothelium, Vascular; Epoprostenol; Female; Humans; In Vitro Techniques; Indomethacin; Leukotriene Antagonists; Leukotriene C4; Leukotriene D4; Leukotrienes; Male; Membrane Proteins; Middle Aged; Propionates; Pulmonary Artery; Quinolines; Receptors, Leukotriene; SRS-A; Vasoconstriction

2000
Hepatocyte-derived cysteinyl leukotrienes modulate vascular tone in experimental cirrhosis.
    Gastroenterology, 2000, Volume: 119, Issue:3

    Topics: Animals; Arachidonate 5-Lipoxygenase; Blood Pressure; Calcium; Carbon Tetrachloride; Cell Size; Cells, Cultured; Culture Media, Conditioned; Cysteine; Intracellular Membranes; Leukotriene D4; Leukotrienes; Liver; Liver Cirrhosis; Male; Osmolar Concentration; Portal System; Rats; Rats, Wistar; Reference Values; RNA, Messenger; Vasomotor System

2000
Intratracheal administration of anaphylatoxin C5a potentiates antigen-induced pulmonary reactions through the prolonged production of cysteinyl-leukotrienes.
    Immunopharmacology, 2000, Volume: 49, Issue:3

    Topics: Airway Resistance; Animals; Antigens; Bile; Chromones; Complement C5a; Complement C5a, des-Arginine; Cysteine; Diphenhydramine; Histamine H1 Antagonists; Hypersensitivity, Immediate; Inflammation Mediators; Injections, Subcutaneous; Intubation, Intratracheal; Leukotriene Antagonists; Leukotriene D4; Leukotriene E4; Leukotrienes; Lung; Male; Membrane Proteins; Ovalbumin; Rats; Rats, Inbred BN; Receptors, Leukotriene; Zymosan

2000
An alternative pathway for metabolism of leukotriene D(4): effects on contractions to cysteinyl-leukotrienes in the guinea-pig trachea.
    British journal of pharmacology, 2001, Volume: 133, Issue:7

    Topics: Animals; Borates; Cysteine; Dicarboxylic Acids; Dose-Response Relationship, Drug; Glutathione; Guinea Pigs; In Vitro Techniques; Indazoles; Leukotriene Antagonists; Leukotriene C4; Leukotriene D4; Leukotriene E4; Leukotrienes; Male; Membrane Proteins; Muscle Contraction; Propionates; Quinolines; Receptors, Leukotriene; Serine; SRS-A; Trachea

2001
Antiallergic effect of ardisiaquinone A, a potent 5-lipoxygenase inhibitor.
    Phytomedicine : international journal of phytotherapy and phytopharmacology, 2001, Volume: 8, Issue:6

    Topics: Animals; Anti-Allergic Agents; Benzoquinones; Bronchoconstriction; Cysteine; Dose-Response Relationship, Drug; Female; Guinea Pigs; Histamine Release; Leukotriene C4; Leukotriene D4; Leukotriene E4; Leukotrienes; Lipoxygenase Inhibitors; Male; Mast Cells; p-Methoxy-N-methylphenethylamine; Rats; Rats, Inbred BN; Rats, Wistar

2001
Cysteinyl leukotrienes induce IL-4 release from cord blood-derived human eosinophils.
    The Journal of allergy and clinical immunology, 2002, Volume: 109, Issue:6

    Topics: Acetophenones; Animals; Cysteine; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Eosinophils; Fetal Blood; Humans; Immunohistochemistry; Inflammation Mediators; Interleukin-4; Isoxazoles; Leukotriene C4; Leukotriene D4; Leukotriene E4; Leukotrienes; Membrane Proteins; Microscopy, Fluorescence; Pertussis Toxin; Propionates; Quinolines; Rabbits; Receptors, Leukotriene; Tetrazoles; Time Factors; Virulence Factors, Bordetella

2002
A functional study on CysLT(1) receptors in human eosinophils.
    International archives of allergy and immunology, 2002, Volume: 129, Issue:1

    Topics: Calcium; Cell Degranulation; Cell Movement; Chemotaxis; Cysteine; Cytokines; Eosinophils; Humans; Leukotriene D4; Leukotrienes; Membrane Proteins; Receptors, Leukotriene; RNA, Messenger

2002
Cysteinyl leukotrienes in the bile of patients with obstructive jaundice.
    Journal of gastroenterology, 2002, Volume: 37, Issue:10

    Topics: Adult; Aged; Aged, 80 and over; Bile; Cholestasis; Chromatography, High Pressure Liquid; Cysteine; Female; Humans; Leukotriene C4; Leukotriene D4; Leukotriene E4; Male; Middle Aged; Radioimmunoassay

2002
Cysteinyl leukotriene-dependent [Ca2+]i responses to angiotensin II in cardiomyocytes.
    American journal of physiology. Heart and circulatory physiology, 2003, Volume: 284, Issue:4

    Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Animals, Newborn; Arginine Vasopressin; Benzoquinones; Calcium; Cysteine; Endothelin-1; Enzyme Inhibitors; Fluorescent Dyes; Fura-2; Heart; Imidazoles; Inositol 1,4,5-Trisphosphate; Leukotriene C4; Leukotriene D4; Leukotrienes; Lipoxygenase Inhibitors; Losartan; Myocardium; Propionates; Pyridines; Quinolines; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Spectrometry, Fluorescence

2003
Cysteinyl leukotrienes in porcine acute allergic airway reactions: bronchial and vascular effects.
    Inflammation research : official journal of the European Histamine Research Society ... [et al.], 2003, Volume: 52, Issue:5

    Topics: Allergens; Animals; Ascaris suum; Blood Vessels; Bronchi; Cysteine; Histamine; Leukotriene D4; Leukotrienes; Propionates; Quinolines; Regional Blood Flow; Respiratory Hypersensitivity; Swine

2003
The cysteinyl-leukotriene D4 induces cytosolic Ca2+ elevation and contraction of the human detrusor muscle.
    The Journal of urology, 2003, Volume: 170, Issue:2 Pt 1

    Topics: Acetates; Calcium; Cells, Cultured; Cyclopropanes; Cysteine; Cytosol; Dose-Response Relationship, Drug; Humans; In Vitro Techniques; Indoles; Leukotriene Antagonists; Leukotriene D4; Leukotrienes; Membrane Proteins; Muscle Contraction; Muscle, Smooth; Phenylcarbamates; Quinolines; Receptors, Leukotriene; Sarcoplasmic Reticulum; Sulfides; Sulfonamides; Tosyl Compounds; Urinary Bladder

2003
Cysteinyl leukotrienes induce nuclear factor kappa b activation and RANTES production in a murine model of asthma.
    The Journal of allergy and clinical immunology, 2003, Volume: 112, Issue:2

    Topics: Animals; Antigens, Dermatophagoides; Asthma; Bronchial Hyperreactivity; Bronchitis; Chemokine CCL5; Chromones; Cysteine; Cytokines; Female; Inflammation Mediators; Leukotriene Antagonists; Leukotriene D4; Leukotrienes; Lung; Mice; Mice, Inbred BALB C; Monocytes; NF-kappa B; Transcription Factor RelA

2003
Interactions among three classes of mediators explain antigen-induced bronchoconstriction in the isolated perfused and ventilated guinea pig lung.
    The Journal of pharmacology and experimental therapeutics, 2003, Volume: 307, Issue:1

    Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Bronchoconstriction; Cysteine; Drug Interactions; Guinea Pigs; Histamine; Histamine Antagonists; Leukotriene D4; Leukotrienes; Lung; Male; Ovalbumin; Perfusion; Pyrilamine; Thromboxanes

2003
Concentrations of cysteinyl leukotrienes in urine and bronchoalveolar lavage fluid of cats with experimentally induced asthma.
    American journal of veterinary research, 2003, Volume: 64, Issue:11

    Topics: Animals; Asthma, Exercise-Induced; Bronchoalveolar Lavage Fluid; Cat Diseases; Cats; Cysteine; Enzyme-Linked Immunosorbent Assay; Leukotriene C4; Leukotriene D4; Leukotriene E4; Leukotrienes

2003
CysLT1 signal transduction in differentiated U937 cells involves the activation of the small GTP-binding protein Ras.
    Biochemical pharmacology, 2004, Apr-15, Volume: 67, Issue:8

    Topics: Calcium; Cysteine; Egtazic Acid; Enzyme Activation; Estrenes; Genistein; GTP-Binding Proteins; Humans; Inflammation Mediators; Leukotriene D4; Leukotrienes; Membrane Proteins; Mitogen-Activated Protein Kinases; Pertussis Toxin; Pyrimidines; Pyrrolidinones; ras Proteins; Receptors, Leukotriene; Signal Transduction; U937 Cells

2004
Cysteinyl leukotrienes are secretagogues in atrophic coeliac and in normal duodenal mucosa of children.
    Scandinavian journal of gastroenterology, 2005, Volume: 40, Issue:2

    Topics: Atrophy; Celiac Disease; Child; Child, Preschool; Cysteine; Duodenum; Humans; Infant; Intestinal Mucosa; Intestines; Leukotriene C4; Leukotriene D4; Leukotrienes; Lipoxygenase; Prostaglandin-Endoperoxide Synthases

2005
Evaluating the prophylactic potential of the phtalimide derivative LASSBio 552 on allergen-evoked inflammation in rats.
    European journal of pharmacology, 2005, Mar-28, Volume: 511, Issue:2-3

    Topics: Allergens; Animals; Anti-Asthmatic Agents; Calcium; CD4-Positive T-Lymphocytes; Cell Movement; Chemokine CCL11; Chemokines, CC; CHO Cells; Cricetinae; Cricetulus; Cysteine; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Eosinophils; Female; Indoles; Inflammation; Isoindoles; Leukotriene D4; Leukotrienes; Male; Membrane Proteins; Phenylcarbamates; Pleura; Pleurisy; Rats; Rats, Wistar; Receptors, Leukotriene; Sulfonamides; Tetrazoles; Tosyl Compounds; Transfection

2005
Cysteinyl-leukotrienes contribute to sputum eosinophil chemotactic activity in asthmatics.
    Allergy, 2006, Volume: 61, Issue:1

    Topics: Adult; Asthma; Biomarkers; Bronchial Provocation Tests; Chemotaxis; Cohort Studies; Cysteine; Enzyme-Linked Immunosorbent Assay; Eosinophils; Female; Humans; Leukotriene D4; Leukotrienes; Male; Middle Aged; Probability; Prognosis; Risk Factors; Sensitivity and Specificity; Sputum; Steroids

2006
Toll-like receptor agonists differentially regulate cysteinyl-leukotriene receptor 1 expression and function in human dendritic cells.
    The Journal of allergy and clinical immunology, 2006, Volume: 117, Issue:5

    Topics: Calcium; Cells, Cultured; Chemotaxis, Leukocyte; Cysteine; Dendritic Cells; Humans; Leukotriene C4; Leukotriene D4; Leukotrienes; Membrane Proteins; Receptors, Leukotriene; Toll-Like Receptors

2006
Cysteinyl-leukotrienes in the regulation of beta2-adrenoceptor function: an in vitro model of asthma.
    Respiratory research, 2006, Jul-28, Volume: 7

    Topics: Adrenergic beta-Agonists; Albuterol; Allergens; Asthma; Bronchi; Bronchodilator Agents; Cells, Cultured; Cyclic AMP; Cysteine; Dose-Response Relationship, Drug; Humans; In Vitro Techniques; Isoproterenol; Leukotriene D4; Leukotrienes; Myocytes, Smooth Muscle; Protein Kinase C; Receptors, Adrenergic, beta-2

2006
CysLT2 receptors interact with CysLT1 receptors and down-modulate cysteinyl leukotriene dependent mitogenic responses of mast cells.
    Blood, 2007, Nov-01, Volume: 110, Issue:9

    Topics: Animals; Cell Proliferation; Cells, Cultured; Cysteine; Extracellular Signal-Regulated MAP Kinases; HeLa Cells; Humans; Leukotriene D4; Leukotrienes; Mast Cells; Membrane Proteins; Mice; Mice, Inbred C57BL; Mice, Knockout; Mitosis; Protein Binding; Proto-Oncogene Proteins c-kit; Receptors, Leukotriene; Transcriptional Activation

2007
IL-10 inhibits cysteinyl leukotriene-induced activation of human monocytes and monocyte-derived dendritic cells.
    Journal of immunology (Baltimore, Md. : 1950), 2008, Jun-01, Volume: 180, Issue:11

    Topics: Cell Migration Inhibition; Chemokine CCL5; Chemotaxis; Chemotaxis, Leukocyte; Cysteine; Dendritic Cells; Humans; Interleukin-10; Leukotriene D4; Leukotrienes; Monocytes; Receptors, Leukotriene; RNA, Messenger; RNA, Small Interfering

2008
The epidermal growth factor receptor mediates allergic airway remodelling in the rat.
    The European respiratory journal, 2008, Volume: 32, Issue:5

    Topics: Allergens; Animals; Cell Proliferation; Cysteine; ErbB Receptors; Gene Expression Profiling; Goblet Cells; Hyperplasia; Inflammation; Leukotriene D4; Muscle, Smooth; Ovalbumin; Quinazolines; Rats; Receptors, Leukotriene; Tyrphostins

2008
Evidence for a pathophysiological role of cysteinyl leukotrienes in classical Hodgkin lymphoma.
    International journal of cancer, 2008, Nov-15, Volume: 123, Issue:10

    Topics: Adolescent; Adult; Aged; Calcium Signaling; Cell Line, Tumor; Child; Child, Preschool; Cysteine; Female; Hodgkin Disease; Humans; Immunohistochemistry; Leukotriene D4; Leukotrienes; Male; Middle Aged; Oligonucleotide Array Sequence Analysis; Polymerase Chain Reaction; Receptors, Leukotriene

2008
Inhaled montelukast inhibits cysteinyl-leukotriene-induced bronchoconstriction in ovalbumin-sensitized guinea-pigs: the potential as a new asthma medication.
    International immunopharmacology, 2009, Volume: 9, Issue:11

    Topics: Acetates; Administration, Inhalation; Animals; Asthma; Bronchial Hyperreactivity; Bronchoconstriction; Cyclopropanes; Cysteine; Disease Models, Animal; Guinea Pigs; Immunologic Factors; Leukotriene Antagonists; Leukotriene C4; Leukotriene D4; Leukotrienes; Lung; Male; Ovalbumin; Quinolines; Sulfides

2009
Regulation of monocyte chemoattractant protein 1 by cysteinyl leukotriene D4 in human lung epithelial A549 cells.
    Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology, 2009, Volume: 103, Issue:4

    Topics: Asthma; Cell Line; Chemokine CCL2; Cysteine; Enzyme-Linked Immunosorbent Assay; Epithelial Cells; Humans; Leukotriene Antagonists; Leukotriene D4; Leukotrienes; Propionates; Quinolines; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger

2009
Injury-related production of cysteinyl leukotrienes contributes to brain damage following experimental traumatic brain injury.
    Journal of neurotrauma, 2009, Volume: 26, Issue:11

    Topics: Animals; Brain Injuries; Chromatography, Liquid; Cysteine; Disease Models, Animal; Enzyme Inhibitors; Indoles; Leukotriene B4; Leukotriene C4; Leukotriene D4; Leukotriene E4; Leukotrienes; Male; Mass Spectrometry; Neutrophils; Rats; Rats, Sprague-Dawley

2009
Concomitant activity of histamine and cysteinyl leukotrienes on porcine nasal mucosal vessels and nasal inflammation in the rat.
    Pharmacology, 2010, Volume: 85, Issue:5

    Topics: Acetates; Animals; Cyclopropanes; Cysteine; Dose-Response Relationship, Drug; Drug Synergism; Drug Therapy, Combination; Female; Histamine; Histamine H1 Antagonists, Non-Sedating; Hypersensitivity; In Vitro Techniques; Leukotriene Antagonists; Leukotriene D4; Leukotrienes; Loratadine; Male; Nasal Mucosa; Neutrophil Infiltration; Quinolines; Rats; Rats, Inbred BN; Rhinitis; Sulfides; Sus scrofa

2010
Augmented venous responsiveness to leukotriene D(4) in nasal septal mucosae of repeatedly antigen-challenged rats.
    European journal of pharmacology, 2010, Oct-10, Volume: 644, Issue:1-3

    Topics: Animals; Antigens; Cysteine; Leukotriene D4; Leukotrienes; Male; Nasal Mucosa; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; omega-N-Methylarginine; Rats; Rats, Wistar; Receptors, Leukotriene; Rhinitis, Allergic, Perennial; Rhinitis, Allergic, Seasonal; RNA, Messenger; Vasodilation

2010
[Effects of agonist and antagonist of cysteinyl leukotriene receptors on differentiation of rat glioma C6 cells].
    Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences, 2011, Volume: 40, Issue:2

    Topics: Acetates; Animals; Cell Differentiation; Cell Line, Tumor; Colforsin; Cyclopropanes; Cysteine; Glioma; Leukotriene Antagonists; Leukotriene D4; Leukotrienes; Quinolines; Rats; Receptors, Leukotriene; Sulfides

2011
The G protein-coupled receptor CysLT1 mediates chemokine-like effects and prolongs survival in chronic lymphocytic leukemia.
    Leukemia & lymphoma, 2012, Volume: 53, Issue:4

    Topics: Acetophenones; Actins; Aged; Apoptosis; Blotting, Western; Calcium; Cell Line, Tumor; Cell Survival; Chemokines; Chemotaxis; Cysteine; Female; Gene Expression Regulation, Neoplastic; Humans; Jurkat Cells; Leukemia, Lymphocytic, Chronic, B-Cell; Leukotriene Antagonists; Leukotriene D4; Leukotrienes; Male; Mitogen-Activated Protein Kinases; Phosphorylation; Propionates; Quinolines; Receptors, Leukotriene; Reverse Transcriptase Polymerase Chain Reaction; Tetrazoles; Time Factors; Tumor Cells, Cultured

2012
Cysteinyl leukotrienes mediate the response of submucosal ganglia from rat colon to bradykinin.
    European journal of pharmacology, 2012, Apr-15, Volume: 681, Issue:1-3

    Topics: Animals; Arachidonic Acid; Arachidonic Acids; Bradykinin; Calcium; Colon; Cysteine; Cytosol; Female; Fura-2; Ganglia; Intestinal Mucosa; Leukotriene D4; Leukotrienes; Lipoxygenases; Phospholipases A2; Propionates; Prostaglandin-Endoperoxide Synthases; Quinacrine; Quinolines; Rats; Rats, Wistar; Receptors, Bradykinin

2012
Human T(H)2 cells respond to cysteinyl leukotrienes through selective expression of cysteinyl leukotriene receptor 1.
    The Journal of allergy and clinical immunology, 2012, Volume: 129, Issue:4

    Topics: Calcium Signaling; Chemotaxis; Cysteine; Gene Expression Profiling; Gene Expression Regulation; GTP-Binding Protein alpha Subunits; Humans; Immunologic Factors; Leukotriene D4; Leukotrienes; Protein Binding; Receptors, Leukotriene; Th2 Cells

2012
Leukotriene D4 and interleukin-13 cooperate to increase the release of eotaxin-3 by airway epithelial cells.
    PloS one, 2012, Volume: 7, Issue:8

    Topics: Asthma; Bronchi; Chemokine CCL24; Chemokine CCL26; Chemokines, CC; Cysteine; Enzyme-Linked Immunosorbent Assay; Epithelial Cells; Flow Cytometry; Gene Expression Regulation; Humans; Inflammation; Interleukin-13; Interleukin-4; Kinetics; Leukotriene D4; Leukotrienes; Models, Biological; Recombinant Proteins; Th2 Cells

2012
Cysteinyl leukotrienes in exhaled breath condensate of smoking asthmatics.
    Clinical chemistry and laboratory medicine, 2013, Volume: 51, Issue:5

    Topics: Adult; Asthma; Breath Tests; Case-Control Studies; Clinical Chemistry Tests; Cysteine; Enzyme-Linked Immunosorbent Assay; Exhalation; Female; Humans; Leukotriene Antagonists; Leukotriene D4; Leukotrienes; Male; Middle Aged; Receptors, Leukotriene; Respiratory Function Tests; Smoking; Surveys and Questionnaires; Young Adult

2013
5-Hydroxyeicosatetraenoic acid and leukotriene D4 increase intestinal epithelial paracellular permeability.
    The international journal of biochemistry & cell biology, 2013, Volume: 45, Issue:7

    Topics: Arachidonate 5-Lipoxygenase; Caco-2 Cells; Cell Line, Tumor; Cyclic AMP-Dependent Protein Kinases; Cysteine; Electric Impedance; Epithelium; Humans; Hydroxyeicosatetraenoic Acids; Inflammatory Bowel Diseases; Intestinal Mucosa; Leukotriene D4; Leukotrienes; Occludin; Permeability; Protein Kinase C; Tight Junctions; Type C Phospholipases

2013
Leukotriene D
    The Journal of allergy and clinical immunology, 2021, Volume: 148, Issue:1

    Topics: Animals; Asthma; Blood Platelets; Cysteine; Cytokines; Leukotriene C4; Leukotriene D4; Leukotriene E4; Leukotrienes; Lung; Male; Mice; Mice, Inbred C57BL; Platelet Activation; Pulmonary Eosinophilia; Receptors, Leukotriene

2021