Compounds > cysteine

cysteine and leukotriene c4

cysteine has been researched along with leukotriene c4 in 45 studies

Research

Studies (45)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's7 (15.56)18.2507
2000's27 (60.00)29.6817
2010's10 (22.22)24.3611
2020's1 (2.22)2.80

Authors

AuthorsStudies
Busse, WW; Sedgwick, JB1
Abram, TS; Brink, C; Cuthbert, NJ; Gardiner, PJ; Norman, P; Tudhope, SR1
Becker, K; Carlsson, B; Hoffmann, GF; Larsson, A; Mayatepek, E1
Broughton, KS; Dietert, RR; Golemboski, KA; Kinsella, JE; Whelan, J1
Boeker, DK; Deinsberger, W; Joedicke, A; Müller, HW; Winking, M1
Jonsson, EW1
Carter, BZ; Lieberman, MW; Reed, DJ; Shields, JE; Will, Y1
Abramovitz, M; Austin, CP; Bellefeuille, JN; Cheng, R; Clements, MK; Coulombe, N; Evans, JF; Figueroa, DJ; George, SR; Heise, CE; Im, DS; Liu, Q; Liu, Y; Lynch, KR; Ma, L; Metters, KM; Nguyen, T; O'Dowd, BF; O'Neill, GP; Sawyer, N; Stocco, R; Williams, DL; Zeng, Z1
Florio, G; Marone, G; Patella, V; Petraroli, A; Triggiani, M1
Bäck, M; Brink, C; Dahlén, S; Gascard, J; Mazmanian, G; Norel, X; Walch, L1
Bäck, M; Brink, C; Dahlén, S; de Montpreville, V; Gascard, J; Norel, X; Walch, L1
Amann, R; Peskar, BA; Schuligoi, R1
Bäck, M; Cotgreave, IA; Dahlén, SE; Kumlin, M1
Akagi, M; Fukuishi, N; Fukuyama, Y; Takada, T1
Kolaczkowska, E; Plytycz, B; Seljelid, R; Shahzidi, S; van Rooijen, N1
Bandeira-Melo, C; Hall, JC; Penrose, JF; Weller, PF1
Chen, Q; Yang, Y; Zhang, JT1
Buchholz, U; Fukui, H; Imazu, H; Keppler, D; Kikuchi, E; Kikukawa, M; Kojima, H; Matsumoto, M; Tsujii, T; Uemura, M1
Gopalakrishnan, V; Liu, P; Misurski, DA1
Bäck, M; Brink, C; Dahlén, SE; Gascard, JP; Norel, X; Walch, L1
Cole, SP; Deeley, RG; Leslie, EM; Létourneau, IJ1
Chang, XB; Cui, L; Hou, YX; Riordan, JR; Yang, R1
Boetticher, E; Bonventre, JV; Cho, W; Han, SK; Kim, KP; Kim, YJ; Leff, AR; Meliton, AY; Muñoz, NM; Myou, S; O'Leary, E; Zhu, X1
Berghaus, LJ; Berghaus, RD; Decile, KC; Gershwin, LJ; Hyde, DM; Norris, CR; Schelegle, ES; Walby, WF1
Brooker, RJ; Dimova-Yaneva, D; Helms, PJ; Main, M; Russell, D1
Chang, XB; Zhao, Q1
Redfors, S; Reims, A; Sjövall, H; Strandvik, B1
Rola-Pleszczynski, M; Stankova, J; Thivierge, M1
Dunsmore, K; Engels, F; Mortaz, E; Nijkamp, FP; Odoms, K; Redegeld, FA; Wong, HR1
Farias, SE; Heidenreich, KA; Murphy, RC; Precht, T; Zarini, S1
Bäck, M1
Chen, Z; Lou, YJ; Ma, KF; Qi, LY; Yang, HY; Zhu, DY1
Ikeda, Y; Imbe, S; Iwanaga, T; Muraki, M; Sato, R; Tohda, Y; Yamagata, S1
Farias, S; Frey, LC; Heidenreich, KA; Murphy, RC1
Chebolu, S; Darmani, NA; Ray, AP; Wang, Y1
Câmara, NO; Hiyane, MI; Landgraf, MA; Landgraf, RG; Pacheco-Silva, A; Silva, RC1
Bakker-Abreu, I; Bandeira-Melo, C; Bozza, PT; Diaz, BL; Luna-Gomes, T; Mesquita-Santos, FP1
Abramovitz, M; Funk, CD; Nesheim, ME; Sawyer, N; Stocco, R; Yan, D1
Bridges, CC; Joshee, L; Zalups, RK1
Ahmad, S; Haeggström, JZ; Lachmann, P; Morgenstern, R; Rinaldo-Matthis, A; Wetterholm, A1
Deeley, RG; Qin, L; Tam, SP1
Accomazzo, MR; Borroni, E; Brivio, I; Buccellati, C; Capra, V; Carnevali, S; Carnini, C; Di Gennaro, A; Fiumicelli, M; Mangano, P; Rovati, G; Sala, A1
Boyce, JA; Feng, C; Garofalo, D; Katz, H; Lai, J; Laidlaw, TM; Liu, T1
Dvash, E; Rubinstein, M1
Barrett, NA; Boyce, JA; Feng, C; Lai, J; Liu, T; Nagai, J1

Reviews

4 review(s) available for cysteine and leukotriene c4

ArticleYear
Eosinophil eicosanoid relations in allergic inflammation of the airways.
    Advances in prostaglandin, thromboxane, and leukotriene research, 1994, Volume: 22

    Topics: Asthma; Cysteine; Eosinophils; Humans; Hypersensitivity; Leukotriene C4; Leukotrienes; Respiratory Tract Diseases

1994
Leukotriene receptors and their selective antagonists.
    Advances in prostaglandin, thromboxane, and leukotriene research, 1994, Volume: 22

    Topics: Animals; Cysteine; Humans; Leukotriene Antagonists; Leukotriene C4; Leukotriene D4; Lung; Receptors, Leukotriene; SRS-A

1994
Functional characterisation of receptors for cysteinyl leukotrienes in smooth muscle.
    Acta physiologica Scandinavica. Supplementum, 1998, Volume: 641

    Topics: Animals; Cysteine; Guinea Pigs; Humans; Ileum; In Vitro Techniques; Leukotriene Antagonists; Leukotriene C4; Leukotriene D4; Leukotriene E4; Leukotrienes; Lung; Muscle, Smooth; Receptors, Leukotriene

1998
Leukotrienes and kidney diseases.
    Current opinion in nephrology and hypertension, 2018, Volume: 27, Issue:1

    Topics: Animals; Anti-Asthmatic Agents; Cell Death; Cysteine; DNA Damage; Glutathione Transferase; Humans; Kidney Diseases; Leukotriene Antagonists; Leukotriene C4; Leukotrienes; NADPH Oxidase 4; Oxidative Stress

2018

Other Studies

41 other study(ies) available for cysteine and leukotriene c4

ArticleYear
Deficient synthesis of cysteinyl leukotrienes in glutathione synthetase deficiency.
    International journal of tissue reactions, 1993, Volume: 15, Issue:6

    Topics: Cysteine; Female; Glutathione; Glutathione Synthase; Humans; Infant, Newborn; Leukotriene C4; Leukotriene E4; Leukotrienes; Metabolism, Inborn Errors; Monocytes; Neutrophils

1993
Characterization of leukotriene production in vivo and in vitro in resident and elicited peritoneal macrophages in chickens and mice.
    Prostaglandins, leukotrienes, and essential fatty acids, 1997, Volume: 56, Issue:1

    Topics: Animals; Calcimycin; Chickens; Cysteine; Dextrans; Ionophores; Kinetics; Leukotriene C4; Leukotriene D4; Leukotriene E4; Leukotrienes; Macrophage Activation; Macrophages, Peritoneal; Male; Mice; Mice, Inbred Strains; Zymosan

1997
Levels of immunoreactive cysteinyl-leukotrienes in CSF after subarachnoid haemorrhage correlate with blood flow-velocity in TCD.
    Acta neurochirurgica, 1997, Volume: 139, Issue:8

    Topics: Adult; Aneurysm, Ruptured; Blood Flow Velocity; Brain; Chromatography, High Pressure Liquid; Cysteine; Enzyme-Linked Immunosorbent Assay; Female; Humans; Intracranial Aneurysm; Leukotriene C4; Leukotriene D4; Leukotriene E4; Leukotrienes; Male; Middle Aged; Postoperative Complications; Subarachnoid Hemorrhage; Ultrasonography, Doppler, Transcranial

1997
Gamma-glutamyl leukotrienase cleavage of leukotriene C4.
    Advances in experimental medicine and biology, 1999, Volume: 469

    Topics: Animals; Cysteine; Dipeptidases; gamma-Glutamyltransferase; Glutathione; Kinetics; Leukotriene C4; Leukotriene D4; Liver; Lung; Mice; Mice, Knockout; Spleen; Substrate Specificity

1999
Characterization of the human cysteinyl leukotriene 2 receptor.
    The Journal of biological chemistry, 2000, Sep-29, Volume: 275, Issue:39

    Topics: Adrenal Medulla; Cloning, Molecular; Cysteine; Humans; Leukotriene Antagonists; Leukotriene C4; Leukotriene D4; Leukotriene E4; Leukotrienes; Lung; Membrane Proteins; Models, Molecular; Myocardium; Receptors, Leukotriene; Recombinant Proteins; Sequence Analysis, DNA; Sequence Homology, Amino Acid; SRS-A; Tissue Distribution

2000
The immunoglobulin superantigen-binding site of HIV-1 gp120 activates human basophils.
    AIDS (London, England), 2000, May-26, Volume: 14, Issue:8

    Topics: Adult; Amino Acid Sequence; Antibodies, Anti-Idiotypic; Basophils; Binding Sites, Antibody; Cyclosporine; Cysteine; Histamine Release; HIV Envelope Protein gp120; HIV-1; HIV-2; Humans; Immunoglobulin E; Immunoglobulin M; Immunosuppressive Agents; Inflammation Mediators; Interleukin-4; Kinetics; Leukotriene C4; Leukotrienes; Molecular Sequence Data; Peptides; Receptors, IgE; Superantigens; Tacrolimus

2000
Antagonist resistant contractions of the porcine pulmonary artery by cysteinyl-leukotrienes.
    European journal of pharmacology, 2000, Aug-11, Volume: 401, Issue:3

    Topics: 6-Ketoprostaglandin F1 alpha; Animals; Cysteine; Dose-Response Relationship, Drug; Endothelium, Vascular; In Vitro Techniques; Indoles; Indomethacin; Leukotriene Antagonists; Leukotriene C4; Leukotriene D4; Leukotriene E4; Leukotrienes; Male; Membrane Proteins; Phenylcarbamates; Pulmonary Artery; Receptors, Leukotriene; SRS-A; Sulfonamides; Swine; Thromboxane A2; Tosyl Compounds; Vasoconstriction

2000
Prostacyclin modulation of contractions of the human pulmonary artery by cysteinyl-leukotrienes.
    European journal of pharmacology, 2000, Aug-11, Volume: 401, Issue:3

    Topics: 6-Ketoprostaglandin F1 alpha; Cysteine; Dose-Response Relationship, Drug; Endothelium, Vascular; Epoprostenol; Female; Humans; In Vitro Techniques; Indomethacin; Leukotriene Antagonists; Leukotriene C4; Leukotriene D4; Leukotrienes; Male; Membrane Proteins; Middle Aged; Propionates; Pulmonary Artery; Quinolines; Receptors, Leukotriene; SRS-A; Vasoconstriction

2000
Effects of COX-1 and COX-2 inhibitors on eicosanoid biosynthesis and the release of substance P from the guinea-pig isolated perfused lung.
    Inflammation research : official journal of the European Histamine Research Society ... [et al.], 2001, Volume: 50, Issue:1

    Topics: 6-Ketoprostaglandin F1 alpha; Animals; Bradykinin; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Cysteine; Eicosanoids; Female; Guinea Pigs; Indomethacin; Inflammation Mediators; Isoenzymes; Leukotriene C4; Leukotrienes; Lung; Male; Nitrobenzenes; Prostaglandin-Endoperoxide Synthases; Pyrazoles; Substance P; Sulfonamides

2001
An alternative pathway for metabolism of leukotriene D(4): effects on contractions to cysteinyl-leukotrienes in the guinea-pig trachea.
    British journal of pharmacology, 2001, Volume: 133, Issue:7

    Topics: Animals; Borates; Cysteine; Dicarboxylic Acids; Dose-Response Relationship, Drug; Glutathione; Guinea Pigs; In Vitro Techniques; Indazoles; Leukotriene Antagonists; Leukotriene C4; Leukotriene D4; Leukotriene E4; Leukotrienes; Male; Membrane Proteins; Muscle Contraction; Propionates; Quinolines; Receptors, Leukotriene; Serine; SRS-A; Trachea

2001
Antiallergic effect of ardisiaquinone A, a potent 5-lipoxygenase inhibitor.
    Phytomedicine : international journal of phytotherapy and phytopharmacology, 2001, Volume: 8, Issue:6

    Topics: Animals; Anti-Allergic Agents; Benzoquinones; Bronchoconstriction; Cysteine; Dose-Response Relationship, Drug; Female; Guinea Pigs; Histamine Release; Leukotriene C4; Leukotriene D4; Leukotriene E4; Leukotrienes; Lipoxygenase Inhibitors; Male; Mast Cells; p-Methoxy-N-methylphenethylamine; Rats; Rats, Inbred BN; Rats, Wistar

2001
Early vascular permeability in murine experimental peritonitis is co-mediated by resident peritoneal macrophages and mast cells: crucial involvement of macrophage-derived cysteinyl-leukotrienes.
    Inflammation, 2002, Volume: 26, Issue:2

    Topics: 6-Ketoprostaglandin F1 alpha; Animals; Capillary Leak Syndrome; Capillary Permeability; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Cysteine; Diterpenes; Eicosanoids; Enzyme Induction; Ginkgolides; Histamine Release; Indoles; Indomethacin; Isoenzymes; Lactones; Leukotriene C4; Leukotrienes; Lipoxygenase Inhibitors; Macrophages, Peritoneal; Male; Mast Cells; Membrane Proteins; Mice; Mice, Inbred BALB C; Mice, Mutant Strains; Nitrobenzenes; Peritonitis; Phospholipid Ethers; Platelet Activating Factor; Prostaglandin-Endoperoxide Synthases; Quinolines; Sulfonamides; Thioglycolates; Zymosan

2002
Cysteinyl leukotrienes induce IL-4 release from cord blood-derived human eosinophils.
    The Journal of allergy and clinical immunology, 2002, Volume: 109, Issue:6

    Topics: Acetophenones; Animals; Cysteine; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Eosinophils; Fetal Blood; Humans; Immunohistochemistry; Inflammation Mediators; Interleukin-4; Isoxazoles; Leukotriene C4; Leukotriene D4; Leukotriene E4; Leukotrienes; Membrane Proteins; Microscopy, Fluorescence; Pertussis Toxin; Propionates; Quinolines; Rabbits; Receptors, Leukotriene; Tetrazoles; Time Factors; Virulence Factors, Bordetella

2002
Structural and functional consequences of mutating cysteine residues in the amino terminus of human multidrug resistance-associated protein 1.
    The Journal of biological chemistry, 2002, Nov-15, Volume: 277, Issue:46

    Topics: Adenosine Triphosphate; Alanine; Amino Acid Sequence; Antineoplastic Agents; Blotting, Western; Cell Membrane; Cell Separation; Cells, Cultured; Colchicine; Cysteine; DNA Mutational Analysis; Dose-Response Relationship, Drug; Doxorubicin; Etoposide; Flow Cytometry; Fluorescent Antibody Technique, Indirect; Glycosylation; Humans; Kinetics; Leukotriene C4; Microscopy, Confocal; Molecular Sequence Data; Multidrug Resistance-Associated Proteins; Mutation; Protein Conformation; Protein Structure, Secondary; Protein Structure, Tertiary; Structure-Activity Relationship; Time Factors; Transfection; Trypsin; Vincristine

2002
Cysteinyl leukotrienes in the bile of patients with obstructive jaundice.
    Journal of gastroenterology, 2002, Volume: 37, Issue:10

    Topics: Adult; Aged; Aged, 80 and over; Bile; Cholestasis; Chromatography, High Pressure Liquid; Cysteine; Female; Humans; Leukotriene C4; Leukotriene D4; Leukotriene E4; Male; Middle Aged; Radioimmunoassay

2002
Cysteinyl leukotriene-dependent [Ca2+]i responses to angiotensin II in cardiomyocytes.
    American journal of physiology. Heart and circulatory physiology, 2003, Volume: 284, Issue:4

    Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Animals, Newborn; Arginine Vasopressin; Benzoquinones; Calcium; Cysteine; Endothelin-1; Enzyme Inhibitors; Fluorescent Dyes; Fura-2; Heart; Imidazoles; Inositol 1,4,5-Trisphosphate; Leukotriene C4; Leukotriene D4; Leukotrienes; Lipoxygenase Inhibitors; Losartan; Myocardium; Propionates; Pyridines; Quinolines; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Spectrometry, Fluorescence

2003
The contraction of the human pulmonary artery by LTC4 is resistant to cysLT1 antagonists and counteracted by prostacyclin release.
    Advances in experimental medicine and biology, 2002, Volume: 507

    Topics: Adult; Aged; Cysteine; Humans; Indomethacin; Kinetics; Leukotriene C4; Leukotrienes; Lung Neoplasms; Middle Aged; Muscle Contraction; Muscle, Smooth, Vascular; Pulmonary Artery

2002
Functional and structural consequences of cysteine substitutions in the NH2 proximal region of the human multidrug resistance protein 1 (MRP1/ABCC1).
    Biochemistry, 2003, May-13, Volume: 42, Issue:18

    Topics: Arsenites; Biological Transport; Cell Membrane; Cysteine; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Green Fluorescent Proteins; HeLa Cells; Humans; Immunoblotting; Leukotriene C4; Luminescent Proteins; Microscopy, Confocal; Models, Biological; Multidrug Resistance-Associated Proteins; Mutagenesis, Site-Directed; Mutation; Protein Binding; Protein Conformation; Recombinant Fusion Proteins; Substrate Specificity; Transfection; Vincristine

2003
ATP binding to the first nucleotide binding domain of multidrug resistance-associated protein plays a regulatory role at low nucleotide concentration, whereas ATP hydrolysis at the second plays a dominant role in ATP-dependent leukotriene C4 transport.
    The Journal of biological chemistry, 2003, Aug-15, Volume: 278, Issue:33

    Topics: Adenosine Triphosphate; Amino Acid Sequence; Amino Acid Substitution; Animals; Binding Sites; Biological Transport; Cell Line; Cricetinae; Cysteine; Enzyme Inhibitors; Ethylmaleimide; Humans; Hydrolysis; Kidney; Leukotriene C4; Mutagenesis; Protein Structure, Tertiary

2003
Human group V phospholipase A2 induces group IVA phospholipase A2-independent cysteinyl leukotriene synthesis in human eosinophils.
    The Journal of biological chemistry, 2003, Oct-03, Volume: 278, Issue:40

    Topics: Animals; Arachidonate 5-Lipoxygenase; Arachidonic Acid; Blotting, Western; Bone Marrow Cells; Calcium; Cell Membrane; Cells, Cultured; Cysteine; Cytochalasin B; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme-Linked Immunosorbent Assay; Eosinophils; Group IV Phospholipases A2; Group V Phospholipases A2; Humans; Hydrolysis; Immunohistochemistry; Leukotriene C4; Leukotrienes; Mice; Microscopy, Fluorescence; Neutrophils; Phosphatidylcholines; Phospholipases A; Phospholipases A2; Phosphorylation; Protein Isoforms; Time Factors

2003
Concentrations of cysteinyl leukotrienes in urine and bronchoalveolar lavage fluid of cats with experimentally induced asthma.
    American journal of veterinary research, 2003, Volume: 64, Issue:11

    Topics: Animals; Asthma, Exercise-Induced; Bronchoalveolar Lavage Fluid; Cat Diseases; Cats; Cysteine; Enzyme-Linked Immunosorbent Assay; Leukotriene C4; Leukotriene D4; Leukotriene E4; Leukotrienes

2003
Eosinophil activation and cysteinyl leukotriene production in infants with respiratory syncytial virus bronchiolitis.
    Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology, 2004, Volume: 34, Issue:4

    Topics: Blood Proteins; Bronchiolitis, Viral; Cysteine; Eosinophil Granule Proteins; Eosinophils; Female; Humans; Infant; Infant, Newborn; Leukotriene C4; Leukotrienes; Male; Nasal Lavage Fluid; Respiratory Syncytial Virus Infections; Respiratory Syncytial Virus, Human; Ribonucleases

2004
Mutation of the aromatic amino acid interacting with adenine moiety of ATP to a polar residue alters the properties of multidrug resistance protein 1.
    The Journal of biological chemistry, 2004, Nov-19, Volume: 279, Issue:47

    Topics: Adenine; Adenosine Triphosphate; Amino Acid Sequence; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Blotting, Western; Cell Line; Cell Membrane; Cysteine; Cystic Fibrosis Transmembrane Conductance Regulator; DNA, Viral; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Genetic Vectors; Humans; Insecta; Kinetics; Leukotriene C4; Models, Chemical; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; Protein Binding; Protein Structure, Tertiary; Sequence Homology, Amino Acid; Tyrosine

2004
Cysteinyl leukotrienes are secretagogues in atrophic coeliac and in normal duodenal mucosa of children.
    Scandinavian journal of gastroenterology, 2005, Volume: 40, Issue:2

    Topics: Atrophy; Celiac Disease; Child; Child, Preschool; Cysteine; Duodenum; Humans; Infant; Intestinal Mucosa; Intestines; Leukotriene C4; Leukotriene D4; Leukotrienes; Lipoxygenase; Prostaglandin-Endoperoxide Synthases

2005
Toll-like receptor agonists differentially regulate cysteinyl-leukotriene receptor 1 expression and function in human dendritic cells.
    The Journal of allergy and clinical immunology, 2006, Volume: 117, Issue:5

    Topics: Calcium; Cells, Cultured; Chemotaxis, Leukocyte; Cysteine; Dendritic Cells; Humans; Leukotriene C4; Leukotriene D4; Leukotrienes; Membrane Proteins; Receptors, Leukotriene; Toll-Like Receptors

2006
Stimulation of cysteinyl leukotriene production in mast cells by heat shock and acetylsalicylic acid.
    European journal of pharmacology, 2007, Apr-30, Volume: 561, Issue:1-3

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Blotting, Western; Cell Survival; Cysteine; Flow Cytometry; Heat-Shock Response; HSP70 Heat-Shock Proteins; Leukotriene C4; Leukotrienes; Mast Cells; Mice; Mice, Inbred BALB C; Toll-Like Receptor 2; Toll-Like Receptor 4; Up-Regulation

2007
Transcellular biosynthesis of cysteinyl leukotrienes in rat neuronal and glial cells.
    Journal of neurochemistry, 2007, Volume: 103, Issue:4

    Topics: Animals; Cell Membrane; Cells, Cultured; Coculture Techniques; Cysteine; Humans; Inflammation Mediators; Leukotriene C4; Leukotrienes; Mice; Mice, Inbred C57BL; Neuroglia; Neurons; Rats; Rats, Sprague-Dawley

2007
Cysteinyl-leukotrienes in cerebrovascular disease: angels and demons?
    Arteriosclerosis, thrombosis, and vascular biology, 2008, Volume: 28, Issue:5

    Topics: Asthma; Cerebrovascular Disorders; Cysteine; Glutathione Transferase; Humans; Leukotriene C4; Leukotrienes; Polymorphism, Single Nucleotide; Stroke

2008
Enhanced expressions and activations of leukotriene C4 synthesis enzymes in D-galactosamine/lipopolysaccharide-induced rat fulminant hepatic failure model.
    World journal of gastroenterology, 2008, May-07, Volume: 14, Issue:17

    Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Blotting, Western; Chromatography, High Pressure Liquid; Cysteine; Disease Models, Animal; Galactosamine; Glutathione Transferase; Immunohistochemistry; Isoenzymes; Leukotriene C4; Leukotrienes; Lipopolysaccharides; Liver; Liver Failure, Acute; Male; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Time Factors; Up-Regulation

2008
Inhaled montelukast inhibits cysteinyl-leukotriene-induced bronchoconstriction in ovalbumin-sensitized guinea-pigs: the potential as a new asthma medication.
    International immunopharmacology, 2009, Volume: 9, Issue:11

    Topics: Acetates; Administration, Inhalation; Animals; Asthma; Bronchial Hyperreactivity; Bronchoconstriction; Cyclopropanes; Cysteine; Disease Models, Animal; Guinea Pigs; Immunologic Factors; Leukotriene Antagonists; Leukotriene C4; Leukotriene D4; Leukotrienes; Lung; Male; Ovalbumin; Quinolines; Sulfides

2009
Injury-related production of cysteinyl leukotrienes contributes to brain damage following experimental traumatic brain injury.
    Journal of neurotrauma, 2009, Volume: 26, Issue:11

    Topics: Animals; Brain Injuries; Chromatography, Liquid; Cysteine; Disease Models, Animal; Enzyme Inhibitors; Indoles; Leukotriene B4; Leukotriene C4; Leukotriene D4; Leukotriene E4; Leukotrienes; Male; Mass Spectrometry; Neutrophils; Rats; Rats, Sprague-Dawley

2009
Pranlukast prevents cysteinyl leukotriene-induced emesis in the least shrew (Cryptotis parva).
    European journal of pharmacology, 2010, Feb-25, Volume: 628, Issue:1-3

    Topics: Animals; Chromones; Cysteine; Dose-Response Relationship, Drug; Eulipotyphla; Female; Immunohistochemistry; Injections; Leukotriene C4; Leukotrienes; Male; Proto-Oncogene Proteins c-fos; SRS-A; Vomiting

2010
Leukotrienes produced in allergic lung inflammation activate alveolar macrophages.
    Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 2010, Volume: 26, Issue:3

    Topics: Acetates; Allergens; Animals; Asthma; Cyclopropanes; Cysteine; Disease Models, Animal; Klebsiella pneumoniae; Leukotriene Antagonists; Leukotriene C4; Leukotrienes; Lung; Macrophages, Alveolar; Male; Nitric Oxide; Ovalbumin; Phagocytosis; Pneumonia; Quinolines; Rats; Rats, Wistar; Receptors, IgG; Sulfides

2010
Co-operative signalling through DP(1) and DP(2) prostanoid receptors is required to enhance leukotriene C(4) synthesis induced by prostaglandin D(2) in eosinophils.
    British journal of pharmacology, 2011, Volume: 162, Issue:8

    Topics: Animals; Calcium; Cyclic AMP-Dependent Protein Kinases; Cysteine; Eosinophils; Humans; Leukotriene C4; Leukotrienes; Male; Mice; Pertussis Toxin; Prostaglandin Antagonists; Prostaglandin D2; Receptors, Immunologic; Receptors, Prostaglandin; Signal Transduction

2011
Differential signaling of cysteinyl leukotrienes and a novel cysteinyl leukotriene receptor 2 (CysLT₂) agonist, N-methyl-leukotriene C₄, in calcium reporter and β arrestin assays.
    Molecular pharmacology, 2011, Volume: 79, Issue:2

    Topics: Aequorin; Animals; Arrestins; Base Sequence; beta-Arrestin 2; beta-Arrestins; Calcium; Cell Line; Cysteine; DNA Primers; Humans; Leukotriene C4; Leukotrienes; Mice; Receptors, Leukotriene; Signal Transduction

2011
MRP2 and the handling of mercuric ions in rats exposed acutely to inorganic and organic species of mercury.
    Toxicology and applied pharmacology, 2011, Feb-15, Volume: 251, Issue:1

    Topics: Animals; ATP-Binding Cassette Transporters; Cell Line; Cysteine; Feces; Humans; Injections, Intravenous; Kidney; Kinetics; Leukotriene C4; Liver; Mercuric Chloride; Methylmercury Compounds; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Rats; Rats, Transgenic; Rats, Wistar; Transfection

2011
Pre-steady-state kinetic characterization of thiolate anion formation in human leukotriene C₄ synthase.
    Biochemistry, 2012, Jan-31, Volume: 51, Issue:4

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Arginine; Binding, Competitive; Biocatalysis; Catalytic Domain; Cysteine; Enzyme Inhibitors; Glutathione; Glutathione Transferase; Humans; Hydrogen-Ion Concentration; Isoenzymes; Kinetics; Leukotriene A4; Leukotriene C4; Molecular Targeted Therapy; Protein Conformation; Protein Subunits; Recombinant Proteins

2012
Effect of multiple cysteine substitutions on the functionality of human multidrug resistance protein 1 expressed in human embryonic kidney 293 cells: identification of residues essential for function.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:7

    Topics: Alanine; Amino Acid Sequence; Amino Acid Substitution; Biological Transport; Cell Line, Transformed; Cell Membrane; Cysteine; Estradiol; Estrone; HEK293 Cells; Humans; Kinetics; Leukotriene C4; Molecular Sequence Data; Multidrug Resistance-Associated Proteins; Structure-Activity Relationship

2012
Autocrine activity of cysteinyl leukotrienes in human vascular endothelial cells: Signaling through the CysLT₂ receptor.
    Prostaglandins & other lipid mediators, 2015, Volume: 120

    Topics: Animals; Autocrine Communication; Cysteine; Human Umbilical Vein Endothelial Cells; Humans; Leukotriene A4; Leukotriene C4; Leukotrienes; Myosin Light Chains; Neutrophils; Permeability; Phosphorylation; Protein Kinase C; Rats; Receptors, Leukotriene; rho GTP-Binding Proteins; Signal Transduction; Stress Fibers

2015
Platelet-driven leukotriene C4-mediated airway inflammation in mice is aspirin-sensitive and depends on T prostanoid receptors.
    Journal of immunology (Baltimore, Md. : 1950), 2015, Jun-01, Volume: 194, Issue:11

    Topics: Allergens; Animals; Aspirin; Asthma; Blood Platelets; Bone Marrow Transplantation; Bronchoalveolar Lavage Fluid; Cysteine; Eosinophilia; Inflammation; Intercellular Adhesion Molecule-1; Leukotriene Antagonists; Leukotriene C4; Leukotrienes; Lung; Mice; Mice, Inbred C57BL; Mice, Knockout; Ovalbumin; Platelet Activation; Receptors, Prostaglandin; Thromboxane A2; Vascular Cell Adhesion Molecule-1

2015
Leukotriene D
    The Journal of allergy and clinical immunology, 2021, Volume: 148, Issue:1

    Topics: Animals; Asthma; Blood Platelets; Cysteine; Cytokines; Leukotriene C4; Leukotriene D4; Leukotriene E4; Leukotrienes; Lung; Male; Mice; Mice, Inbred C57BL; Platelet Activation; Pulmonary Eosinophilia; Receptors, Leukotriene

2021