cysteine has been researched along with indomethacin in 45 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 23 (51.11) | 18.7374 |
| 1990's | 10 (22.22) | 18.2507 |
| 2000's | 7 (15.56) | 29.6817 |
| 2010's | 4 (8.89) | 24.3611 |
| 2020's | 1 (2.22) | 2.80 |
| Authors | Studies |
|---|---|
| Abraham, WM; Jackowski, JT; Tomioka, K | 1 |
| Brendel, JK; Buckner, CK; Fishleder, RI; Graziano, FM; Ro, JY | 1 |
| Balint, GA | 2 |
| Hayashi, M; Matsunaga, K; Mita, S; Okahara, A | 1 |
| Abram, TS; Cuthbert, NJ; Gardiner, PJ | 1 |
| Hayashi, M; Iso, T; Kasamatsu, S; Nakata, K; Sasano, M; Suda, H; Yamauchi, H | 1 |
| Bender, RH; Carlson, RP; Chang, J; Hand, JM; Kreft, AF; Kubrak, DM; Musser, JH | 1 |
| Delank, WK; Luck, W; Peskar, BA; Simmet, T | 1 |
| Kalf, GF; Schlosser, MJ | 1 |
| Auen, MA; Chang, J; Hand, JM; Kreft, AF; Musser, JH; Schwalm, SF | 1 |
| Glaise, D; Guillouzo, A; Ratanasavanh, D; Vandenberghe, Y | 1 |
| Mechanic, GL; Reich, R; Tsafriri, A | 1 |
| Klaus, W; König, E; Rösen, R | 1 |
| Edelmann, M; Müller, KM; Peskar, BA; Peskar, BM; Simmet, T; Wittmann, G | 1 |
| Dembińska-Kieć, A; Peskar, BA; Peskar, BM | 1 |
| Benveniste, J; Bourdillat, B; Brink, C; Haye-Legrand, I; Labat, C; Norel, X; Raffestin, B | 1 |
| Hayashi, M; Iso, T; Kasamatsu, S; Mibu, H; Nakata, K; Yamauchi, H | 1 |
| Douglas, JR; Jaffe, BM; Johnson, EM; Marshall, GR; Needleman, P | 1 |
| Butler, M; Giannina, T; Steinetz, B | 1 |
| Famaey, JP; Mockel, J | 1 |
| Brown, JH; Mackey, HK | 1 |
| Benveniste, J; Hadji, L; Mencia-Huerta, JM | 1 |
| Bach, MK; Bloor, CM; Hugli, TE; Stimler, NP | 1 |
| Chakravarty, N | 1 |
| Karim, SM; Roy, AC; Yeang, M | 2 |
| Bögi, J; Imre, G | 1 |
| Kakác, B; Matousová, O; Peterková, M | 1 |
| Monteiro-Riviere, NA; Riviere, JE; Zhang, Z | 1 |
| Pawlowski, JE; Penning, TM | 1 |
| Burakoff, R; Burton, MB; Glaws, WR; Percy, WH; Rose, K | 1 |
| Enomoto, H; Horiuchi, M; Mita, S; Miyake, Y; Tsuji, F | 1 |
| Bäck, M; Brink, C; Dahlén, S; Gascard, J; Mazmanian, G; Norel, X; Walch, L | 1 |
| Bäck, M; Brink, C; Dahlén, S; de Montpreville, V; Gascard, J; Norel, X; Walch, L | 1 |
| Bates, JN; Hoque, A; Lewis, SJ; Travis, MD | 1 |
| Amann, R; Peskar, BA; Schuligoi, R | 1 |
| Kolaczkowska, E; Plytycz, B; Seljelid, R; Shahzidi, S; van Rooijen, N | 1 |
| Bäck, M; Brink, C; Dahlén, SE; Gascard, JP; Norel, X; Walch, L | 1 |
| Elsas, MI; Elsas, PX; Kanaoka, Y; Lam, BK; Mendonça-Sales, SC; Queto, T | 1 |
| Hahm, KB; Han, YM; Jung, MK; Kangwan, N; Kim, EH; Lee, SY; Park, JM | 1 |
| Chen, C; Chen, P; Cui, R; Hu, M; Liu, F; Ren, Y; Yu, H | 1 |
| Dittrich, M; Greiner, C; Hieke, M; Reisen, F; Schneider, G; Schubert-Zsilavecz, M; Werz, O | 1 |
| Barz, D; Dehm, F; Hanke, T; Kaiser, A; Kunze, J; Lämmerhofer, M; Liening, S; Maczewsky, J; Pillong, M; Popella, SD; Sautebin, L; Schneider, G; Schubert-Zsilavecz, M; Weinigel, C; Werz, O; Wurglics, M | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
1 review(s) available for cysteine and indomethacin
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
44 other study(ies) available for cysteine and indomethacin
| Article | Year |
|---|---|
Characterization of sulfidopeptide leukotriene responses in sheep tracheal smooth muscle in vitro.
Topics: Animals; Ascaris; Borates; Carbachol; Cysteine; Female; Hypersensitivity; In Vitro Techniques; Indomethacin; Leukotriene E4; Leukotrienes; Muscle, Smooth; Phenylpropionates; Sheep; SRS-A; Thiadiazoles; Trachea | 1991 |
Influence of indomethacin and L-cysteine on histamine and peptidoleukotriene release from superfused tracheas taken from guinea pigs passively sensitized with IgG1 and IgE antibodies.
Topics: Animals; Cysteine; Female; Guinea Pigs; Histamine Release; Immunization; Immunoglobulin E; Immunoglobulin G; Indomethacin; Leukotrienes; Muscle Contraction; Trachea | 1991 |
Possibilities to reduce the unwanted gastric side-effects of orally administered indomethacin in the rat.
Topics: Administration, Oral; Animals; Cysteine; Epoprostenol; Female; Gastrointestinal Hemorrhage; Indomethacin; Pilot Projects; Rats; Rats, Inbred Strains; Stomach Ulcer | 1991 |
Effect of bucillamine (SA96) on type II collagen induced arthritis in rats.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Experimental; Cell Division; Collagen; Cysteine; Dose-Response Relationship, Drug; Indomethacin; Male; Penicillamine; Rats; Synovial Membrane | 1991 |
Evidence for two leukotriene receptor types in the guinea-pig isolated ileum.
Topics: Animals; Borates; Chromones; Cyclooxygenase Inhibitors; Cysteine; Dicarboxylic Acids; Guinea Pigs; Ileum; In Vitro Techniques; Indazoles; Indomethacin; Leukotriene E4; Male; Receptors, Immunologic; Receptors, Leukotriene; Serine; SRS-A; Stereoisomerism | 1990 |
[Pharmacological studies on N-(2-mercapto-2-methylpropanoyl)-L-cysteine(SA96). IV. Effects of SA96 and its main metabolite, SA679, on denaturation of human gamma-globulin and adjuvant arthritis in rats].
Topics: Animals; Anti-Inflammatory Agents; Arthritis; Arthritis, Experimental; Cysteine; gamma-Globulins; Indomethacin; Male; Organ Size; Penicillamine; Protein Denaturation; Rats; Rats, Inbred Lew; Serum Albumin, Bovine | 1985 |
N-[(arylmethoxy)phenyl] and N-[(arylmethoxy)naphthyl] sulfonamides: potent orally active leukotriene D4 antagonists of novel structure.
Topics: Acetophenones; Animals; Bronchi; Chemical Phenomena; Chemistry; Constriction, Pathologic; Cyclooxygenase Inhibitors; Cysteine; Edema; Guinea Pigs; Hydroxyquinolines; Indomethacin; Inflammation; Lipoxygenase Inhibitors; Molecular Structure; Muscle Contraction; Naphthalenes; SRS-A; Structure-Activity Relationship; Sulfonamides; Tetrazoles; Trachea | 1989 |
Biosynthesis of cysteinyl-leukotrienes by human brain tissue in vitro.
Topics: Brain; Calcimycin; Cysteine; Humans; In Vitro Techniques; Indomethacin; Leukotrienes; Masoprocol; SRS-A | 1989 |
Metabolic activation of hydroquinone by macrophage peroxidase.
Topics: Animals; Ascitic Fluid; Benzoquinones; Biotransformation; Cysteine; Hydroquinones; Indomethacin; Kinetics; Macrophages; Male; Mice; Mice, Inbred C57BL; Peroxidase; Phenol; Phenols; Prostaglandin-Endoperoxide Synthases; Protein Binding; Quinones | 1989 |
Wy-48,252 (1,1,1-trifluoro-N-[3-(2-quinolinylmethoxy)phenyl]methane sulfonamide) an orally active leukotriene D4 antagonist: pharmacological characterization in vitro and in vivo in the guinea pig.
Topics: Animals; Bronchi; Capillary Permeability; Cysteine; Guinea Pigs; Histamine; Hydroxyquinolines; In Vitro Techniques; Indomethacin; Male; Muscle Contraction; Muscle, Smooth; Ovalbumin; SRS-A; Trachea | 1989 |
Influence of medium composition and culture conditions on glutathione S-transferase activity in adult rat hepatocytes during culture.
Topics: Animals; Cell Survival; Cells, Cultured; Culture Media; Cysteine; Cytochrome P-450 Enzyme System; Dimethyl Sulfoxide; Glutathione Transferase; Indomethacin; Liver; Niacinamide; Rats; Selenium | 1988 |
The involvement of collagenolysis in ovulation in the rat.
Topics: Aminocaproic Acid; Animals; Catechols; Collagen; Cysteine; Female; Gonadotropins, Equine; Indomethacin; Masoprocol; Microbial Collagenase; Ovary; Ovulation; Plasminogen Activators; Proline; Rats; Rats, Inbred Strains | 1985 |
Different sensitivities of arteries and veins to glyceryltrinitrate-induced relaxation and tolerance: an "in vitro" study on isolated vessels from rabbits.
Topics: Animals; Arteries; Cysteine; Drug Tolerance; In Vitro Techniques; Indomethacin; Muscle Relaxation; Muscle, Smooth, Vascular; Nitroglycerin; Norepinephrine; Rabbits; Veins | 1987 |
Formation of cysteinyl-containing leukotrienes by human arterial tissues.
Topics: Adult; Aged; Arteries; Calcimycin; Cysteine; Female; Humans; In Vitro Techniques; Indomethacin; Kinetics; Male; Masoprocol; Middle Aged; SRS-A | 1987 |
Release of cysteinyl-leukotrienes is of minor importance in PAF induced reduction of perfusion rate in the gastric vascular bed.
Topics: Animals; Chromones; Cysteine; Diterpenes; Ginkgolides; Indomethacin; Lactones; Leukotrienes; Male; Masoprocol; Platelet Activating Factor; Rats; Rats, Inbred Strains; Splanchnic Circulation; SRS-A; Stomach | 1988 |
Effects of various pharmacological agents on isolated human bronchial and pulmonary arterial and venous muscle preparations contracted by leukotriene D4.
Topics: Arteries; Bronchi; Carbachol; Chromones; Cysteine; Diltiazem; Dose-Response Relationship, Drug; Female; Histamine; Humans; In Vitro Techniques; Indomethacin; Lung; Male; Muscle, Smooth, Vascular; SRS-A; Veins | 1987 |
[Pharmacological studies of N-(2-mercapto-2-methylpropanoyl)-L-cysteine (SA96). V. Effects of SA96 in combination with indomethacin or prednisolone on adjuvant arthritis in rats].
Topics: Animals; Anti-Inflammatory Agents; Arthritis; Arthritis, Experimental; Blood Proteins; Blood Sedimentation; Copper; Cysteine; Drug Therapy, Combination; Edema; Indomethacin; Male; Prednisolone; Rats; Rats, Inbred Lew | 1985 |
Stimulation of splenic prostaglandin release by angiotensin and specific inhibition by cysteine 8-AII.
Topics: Angiotensin II; Animals; Biological Assay; Chickens; Colon; Cysteine; Depression, Chemical; Female; Indomethacin; Perfusion; Prostaglandins; Rabbits; Rats; Rectum; Spleen; Stimulation, Chemical; Stomach | 1973 |
The role of sulfhydryl groups in three models of inflammatory disease.
Topics: Animals; Arthritis; Carrageenan; Croton Oil; Cyclophosphamide; Cysteine; Dexamethasone; Disulfides; Edema; Ethylmaleimide; Freund's Adjuvant; Glycoproteins; Granuloma; Indomethacin; Male; Penicillamine; Rats; Sulfhydryl Compounds | 1973 |
Importance of sulfhydryl groups for the uncoupling activity of non-steroidal acidic anti-inflammatory drugs and valinomycin in oxidative phosphorylation.
Topics: Adenosine Diphosphate; Animals; Anti-Inflammatory Agents; Cysteine; Dinitrophenols; Flufenamic Acid; In Vitro Techniques; Indomethacin; Kinetics; Membranes; Mitochondria, Liver; Oligomycins; Organomercury Compounds; Oxidation-Reduction; Oxidative Phosphorylation; Potassium; Propionates; Rats; Sulfhydryl Compounds; Time Factors; Uncoupling Agents; Valinomycin | 1973 |
Inhibition of heat-induced denaturation of serum proteins by mixtures of nonsteroidal anti-inflammatory agents and amino acids.
Topics: Amino Acids; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Cysteine; Depression, Chemical; Flufenamic Acid; Fluorine; Histamine; Histidine; Hot Temperature; Indomethacin; ortho-Aminobenzoates; Phenylalanine; Phenylbutazone; Protein Denaturation; Serine; Serum Albumin, Bovine; Solutions; Tryptophan; Tyrosine | 1968 |
Release of a slow-reacting substance from rabbit platelets.
Topics: 5,8,11,14-Eicosatetraynoic Acid; Adenosine Diphosphate; Animals; Arachidonic Acids; Aspirin; Autacoids; Blood Platelets; Chromatography, High Pressure Liquid; Cysteine; Indomethacin; Kinetics; Lysophosphatidylcholines; Platelet Activating Factor; Platelet Aggregation; Rabbits; Thrombin | 1981 |
Release of leukotrienes from guinea pig lung stimulated by C5ades Arg anaphylatoxin.
Topics: Anaphylatoxins; Animals; Chromatography, High Pressure Liquid; Complement C5; Complement C5a; Cysteine; Guinea Pigs; Histamine Release; Indomethacin; Lung; Muscle Contraction; Peptides; Pyrilamine; SRS-A; Swine | 1982 |
Effect of arachidonic acid metabolism on the release of histamine and SRS (leukotrienes) from guinea-pig lung.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Cysteine; Guinea Pigs; Histamine Release; In Vitro Techniques; Indomethacin; Ketoprofen; Lipoxygenase Inhibitors; Lung; Male; Mast Cells; SRS-A | 1984 |
Inhibition of serum oxytocinase activity by prostaglandins.
Topics: Aminopeptidases; Cyclic GMP; Cysteine; Cystinyl Aminopeptidase; Humans; In Vitro Techniques; Indomethacin; Polyphloretin Phosphate; Prostaglandins E; Prostaglandins F; Saline Solution, Hypertonic; Urea | 1981 |
pH dependent inhibition of serum oxytocinase activity by prostaglandins and cyclic GMP.
Topics: Aminopeptidases; Anilides; Cyclic GMP; Cysteine; Cystinyl Aminopeptidase; Female; Humans; Hydrogen-Ion Concentration; Hydrolysis; In Vitro Techniques; Indomethacin; Leucine; Polyphloretin Phosphate; Pregnancy; Prostaglandins | 1982 |
[Causal treatment of corneal vascularization (author's transl)].
Topics: Corneal Diseases; Cysteine; Edema; Glucose; Glycerol; Humans; Indomethacin; Lactates | 1980 |
[Photometric determination of indomethacin and its tropic acid ester (troposin)].
Topics: Cysteine; Flavoring Agents; Indomethacin; Spectrophotometry | 1980 |
Evaluation of protective effects of sodium thiosulfate, cysteine, niacinamide and indomethacin on sulfur mustard-treated isolated perfused porcine skin.
Topics: Animals; Cysteine; Dinoprostone; Female; Indomethacin; Mustard Gas; Niacinamide; Skin; Skin Diseases; Swine; Thiosulfates | 1995 |
Overexpression and mutagenesis of the cDNA for rat liver 3 alpha-hydroxysteroid/dihydrodiol dehydrogenase. Role of cysteines and tyrosines in catalysis.
Topics: 3-alpha-Hydroxysteroid Dehydrogenase (B-Specific); 3-Hydroxysteroid Dehydrogenases; Animals; Base Sequence; Catalysis; Cloning, Molecular; Cysteine; DNA, Complementary; Escherichia coli; Indomethacin; Kinetics; Liver; Molecular Sequence Data; Mutagenesis; Rats; Tyrosine | 1994 |
Pharmacological basis of contractile effects of peptidoleukotrienes on rabbit colonic muscularis mucosae.
Topics: Animals; Borates; Colon; Cysteine; Gastrointestinal Motility; Indomethacin; Leukotrienes; Male; Muscle, Smooth; Peptides; Prostaglandins; Rabbits; Serine; Sulfides | 1993 |
A novel approach to reduce the unwanted gastric side-effects of orally administered non-steroidal anti-inflammatory drugs in rats.
Topics: Administration, Oral; Animals; Anti-Inflammatory Agents, Non-Steroidal; Cysteine; Drug Therapy, Combination; Epoprostenol; Female; Gastric Mucosa; Gastrointestinal Diseases; Glutathione; Indomethacin; Penicillamine; Piroxicam; Rats; Rats, Wistar | 1997 |
Effects of SA6541, a leukotriene A4 hydrolase inhibitor, and indomethacin on carrageenan-induced murine dermatitis.
Topics: Aniline Compounds; Animals; Carrageenan; Cysteine; Dermatitis, Contact; Edema; Enzyme Inhibitors; Epoxide Hydrolases; Indomethacin; Leukotriene B4; Male; Mice; Mice, Inbred ICR | 1998 |
Antagonist resistant contractions of the porcine pulmonary artery by cysteinyl-leukotrienes.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Cysteine; Dose-Response Relationship, Drug; Endothelium, Vascular; In Vitro Techniques; Indoles; Indomethacin; Leukotriene Antagonists; Leukotriene C4; Leukotriene D4; Leukotriene E4; Leukotrienes; Male; Membrane Proteins; Phenylcarbamates; Pulmonary Artery; Receptors, Leukotriene; SRS-A; Sulfonamides; Swine; Thromboxane A2; Tosyl Compounds; Vasoconstriction | 2000 |
Prostacyclin modulation of contractions of the human pulmonary artery by cysteinyl-leukotrienes.
Topics: 6-Ketoprostaglandin F1 alpha; Cysteine; Dose-Response Relationship, Drug; Endothelium, Vascular; Epoprostenol; Female; Humans; In Vitro Techniques; Indomethacin; Leukotriene Antagonists; Leukotriene C4; Leukotriene D4; Leukotrienes; Male; Membrane Proteins; Middle Aged; Propionates; Pulmonary Artery; Quinolines; Receptors, Leukotriene; SRS-A; Vasoconstriction | 2000 |
Blockade of voltage-sensitive Ca(2+)-channels markedly diminishes nitric oxide- but not L-S-nitrosocysteine- or endothelium-dependent vasodilation in vivo.
Topics: Acetylcholine; Animals; Calcium Channel Blockers; Calcium Channels; Cysteine; Endothelium, Vascular; Hemodynamics; Hydrazines; Indomethacin; Male; Nifedipine; Nitric Oxide; Nitroprusside; Nitroso Compounds; Rats; Rats, Sprague-Dawley; S-Nitrosothiols; Sodium Chloride; Vasodilation; Vasodilator Agents | 2000 |
Effects of COX-1 and COX-2 inhibitors on eicosanoid biosynthesis and the release of substance P from the guinea-pig isolated perfused lung.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Bradykinin; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Cysteine; Eicosanoids; Female; Guinea Pigs; Indomethacin; Inflammation Mediators; Isoenzymes; Leukotriene C4; Leukotrienes; Lung; Male; Nitrobenzenes; Prostaglandin-Endoperoxide Synthases; Pyrazoles; Substance P; Sulfonamides | 2001 |
Early vascular permeability in murine experimental peritonitis is co-mediated by resident peritoneal macrophages and mast cells: crucial involvement of macrophage-derived cysteinyl-leukotrienes.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Capillary Leak Syndrome; Capillary Permeability; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Cysteine; Diterpenes; Eicosanoids; Enzyme Induction; Ginkgolides; Histamine Release; Indoles; Indomethacin; Isoenzymes; Lactones; Leukotriene C4; Leukotrienes; Lipoxygenase Inhibitors; Macrophages, Peritoneal; Male; Mast Cells; Membrane Proteins; Mice; Mice, Inbred BALB C; Mice, Mutant Strains; Nitrobenzenes; Peritonitis; Phospholipid Ethers; Platelet Activating Factor; Prostaglandin-Endoperoxide Synthases; Quinolines; Sulfonamides; Thioglycolates; Zymosan | 2002 |
The contraction of the human pulmonary artery by LTC4 is resistant to cysLT1 antagonists and counteracted by prostacyclin release.
Topics: Adult; Aged; Cysteine; Humans; Indomethacin; Kinetics; Leukotriene C4; Leukotrienes; Lung Neoplasms; Middle Aged; Muscle Contraction; Muscle, Smooth, Vascular; Pulmonary Artery | 2002 |
Cysteinyl leukotrienes mediate the enhancing effects of indomethacin and aspirin on eosinophil production in murine bone marrow cultures.
Topics: 5-Lipoxygenase-Activating Proteins; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Bone Marrow Cells; Carrier Proteins; Cells, Cultured; Cyclooxygenase Inhibitors; Cysteine; Dinoprostone; Eosinophils; Female; Glutathione Transferase; Indomethacin; Leukotrienes; Male; Membrane Proteins; Mice; Mice, Inbred BALB C; Signal Transduction | 2008 |
S-allyl cysteine alleviates nonsteroidal anti-inflammatory drug-induced gastric mucosal damages by increasing cyclooxygenase-2 inhibition, heme oxygenase-1 induction, and histone deacetylation inhibition.
Topics: Animals; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Cyclooxygenase 2; Cysteine; Cytoprotection; Dose-Response Relationship, Drug; Female; Gastric Mucosa; Heme Oxygenase-1; Histone Deacetylases; In Vitro Techniques; Indomethacin; Mice, Inbred C57BL; Stomach Ulcer | 2014 |
S-allyl-L-cysteine protects hepatocytes from indomethacin-induced apoptosis by attenuating endoplasmic reticulum stress.
Topics: Animals; Apoptosis; Cells, Cultured; Cysteine; Endoplasmic Reticulum Stress; Hepatocytes; Indomethacin; Protective Agents; Rats | 2020 |
Discovery and biological evaluation of a novel class of dual microsomal prostaglandin E2 synthase-1/5-lipoxygenase inhibitors based on 2-[(4,6-diphenethoxypyrimidin-2-yl)thio]hexanoic acid.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Arachidonate 5-Lipoxygenase; Benzene Derivatives; Binding Sites; Caproates; Cells, Cultured; Cyclooxygenase Inhibitors; Humans; Intramolecular Oxidoreductases; Ligands; Lipoxygenase Inhibitors; Microsomes; Models, Molecular; Prostaglandin-E Synthases; Pyrimidines; Recombinant Proteins; Structure-Activity Relationship | 2011 |
Aminothiazole-featured pirinixic acid derivatives as dual 5-lipoxygenase and microsomal prostaglandin E2 synthase-1 inhibitors with improved potency and efficiency in vivo.
Topics: Animals; Arachidonate 5-Lipoxygenase; Binding Sites; Drug Design; Humans; Hydrophobic and Hydrophilic Interactions; Inhibitory Concentration 50; Intramolecular Oxidoreductases; Lipoxygenase Inhibitors; Male; Mice; Microsomes; Models, Molecular; Peritonitis; Prostaglandin-E Synthases; Protein Conformation; Pyrimidines; Structure-Activity Relationship; Thiazoles; Zymosan | 2013 |