cysteine and guanosine triphosphate

cysteine has been researched along with guanosine triphosphate in 78 studies

Research

Studies (78)

TimeframeStudies, this research(%)All Research%
pre-199010 (12.82)18.7374
1990's30 (38.46)18.2507
2000's24 (30.77)29.6817
2010's11 (14.10)24.3611
2020's3 (3.85)2.80

Authors

AuthorsStudies
Izumi, H; Ozawa, H1
Carlson, GM; Colombo, G; Lardy, HA2
Vuorinen, P1
Anborgh, PH; Jonák, J; Parmeggiani, A1
Johnson, WC; Palczewski, K; Riazance-Lawrence, JH1
Fromm, HJ; Soans, C1
Bourne, HR; McCormick, F; Sanders, DA1
Imai, S; Kitamura, Y; Matsueda, R; Nomura, Y1
Akino, T; Fukada, Y; Ohguro, H; Shimonishi, Y; Takao, T; Yoshizawa, T1
Appel, M; Klingenberg, M1
Baba, A; Iwata, H; Nishiuchi, Y; Tatsuno, T; Uemura, A1
Little, M; Ludueña, RF1
Elstner, EF; Suhadolnik, RJ1
Bishop, L; Bishop, M; Burnett, JB; Colman, RF; Rosen, NL1
Barboni, E; Costa, M; Fiori, A1
Kassab, R; Pradel, LA; Roustan, C; Van Thoai, N1
Morrison, DF; O'Brien, PJ; Pepperberg, DR1
Bell, RM; Brtva, TR; Campbell-Burk, S; Der, CJ; Drugan, JK; Ghosh, S; Terrell, RS1
Cavenagh, M; Clark, J; Kahn, RA; Randazzo, PA; Rulka, C; Stearns, T; Terui, T; Zhang, CJ1
Boss, GR; Pilz, RB; Quilliam, LA; Scheele, JS1
Bell, RM; Ghosh, S; Mabrouk, GM; Quest, AF; Strum, JC; Xie, WQ1
Neer, EJ; Schmidt, CJ; Thomas, TC1
Cardemil, E; Encinas, MV; Kemp, RG; Latshaw, SP; Rojas, MC1
Boekhoff, I; Breer, H; Restrepo, D1
Himes, RH; Mejillano, MR; Shivanna, BD; Williams, TD1
Carlson, GM; Cassell, RG; Lewis, CT; Seyer, JM1
Helms, JB; Kneusel, RE; Nickel, W; Wieland, FT1
Demeure, MJ; Doffek, KM; Gorski, J; Komorowski, RA1
Farrens, DL; Hubbell, WL; Khorana, HG; Yang, K1
Chen, L; Gilbert, BA; Rando, RR; Tashjian, AH; Xu, Y1
Adam, SA; Chi, NC1
Haber, E; Lai, K; Lee, ME; Perrella, MA; Tsai, JC; Wang, H; Yoshizumi, M1
Delves, CJ; Gorman, C; Lowe, PN; Skelly, JV1
Hlavaty, JJ; Nowak, T1
Bai, R; Choe, K; Ewell, JB; Hamel, E; Nguyen, NY1
Baker, TL; Booden, MA; Buss, JE; Der, CJ; Punke, SG; Solski, PA1
Backlund, PS; Caron, JM; Chen, CK; Druey, KM; Jones, TL; Ugur, O1
Gilman, AG; Mukhopadhyay, S; Posner, BA; Ross, EM; Tesmer, JJ1
Assmann, SM; Lee, YR1
Kowluru, A1
Tabancay, AP; Tamanoi, F; Urano, J; Yang, W1
Alexandrov, K; Goody, RS; Scheidig, AJ1
Eu, JP; Greenberg, CS; Hausladen, A; Lai, TS; Slaughter, TF; Stamler, JS1
Bubis, J; Möller, C; Ortiz, JO1
de Wit, JG; den Blaauwen, T; Driessen, AJ; Scheffers, DJ1
Bao, Z; Bowers, KE; Dixon, JE; Fierke, CA; Shao, F; Vacratsis, PO1
Chen, CK; Davey, PC; Druey, KM; Fischer, ER; Hiol, A; Jones, TL; Milligan, G; Osterhout, JL; Waheed, AA1
Baker, TL; Buss, JE; Coloff, JL; Walker, J; Zheng, H1
Aguado, C; Armengod, ME; Knecht, E; Martínez-Vicente, M; Villarroya, M; Yim, L1
Banères, JL; Parello, J1
Krishnamurthy, G; Smith, D; Tawa, G; Wang, Y; Young, KH1
Jones, TL1
Bertoni, A; Cariello, L; Ristoratore, F; Zanetti, L1
Chang, TS; Jeong, W; Lee, SM; Park, S; Rhee, SG; Woo, HA1
Britto, PJ; Knipling, L; McPhie, P; Wolff, J1
Chen, Y; Erickson, HP1
Nakagawa, M; Takahashi, K; Yamanaka, S; Young, SG1
Aspuria, PJ; Comiso, MJ; Deniskin, R; Guo, L; Kato-Stankiewicz, J; Tabancay, AP; Tamanoi, F; Urano, J1
Begg, GE; Carrington, L; Graham, RM; Husain, A; Iismaa, SE; Lorand, L; Matthews, JM; Stokes, PH; Wouters, MA1
Buschauer, A; Dove, S; Ghorai, P; Kraus, A; Preuss, H; Seifert, R1
Nechifor, R; Wilson, KS1
Heo, J1
Herrmann, C; Kunzelmann, S; Vöpel, T1
Adolf, F; Beck, R; Briggs, JA; Brügger, B; Diestelkötter-Bachert, P; Hoehner, K; Prinz, S; Röhling, S; Ronchi, P; Welsch, S; Wieland, F1
Dever, TE; Dong, J; Kim, JR; Lorsch, JR; Shin, BS; Walker, SE1
Bill, E; Lill, R; Netz, DJ; Pallesen, LJ; Pierik, AJ; Sharma, AK; Stümpfig, M; Walden, WE1
Kil, IS; Park, JW; Shin, SW1
Ahn, JY; Cho, SW; Choi, SY; Ha, SC; Hwang, EY; Kim, EA; Son, HJ1
Brodbelt, JS; Browning, KS; Mayberry, LK; Murphy, PA; O'Brien, JP1
Ostrem, JM; Peters, U; Shokat, KM; Sos, ML; Wells, JA1
Dancis, A; Ghosh, AK; Pain, D; Pain, J; Pandey, A1
Bubis, J; Möller, C; Perdomo, D1
Alvarado-Kristensson, M; Crneta, E; Hellsten, R; Lehn, S; Lindström, L; Nilsson, E; Olsson, R; Villoutreix, BO1
Hansen, R; Li, LS; Lito, P; Rosen, N; Solomon, M1
Cohen, H; Gardner, MK; Goldblum, RR; Gonzalez, SJ; Higgins, L; Markowski, TW; McClellan, M; Metzger, JM; Thompson, BR; Vang, HX; White, K; Yang, TY1
Addeo, A; Banna, G; Desai, A; Friedlaender, A; Liu, SV; Parikh, K; Subbiah, V1
Hisabori, T; Horie, M; Kore-Eda, S; Kumaki, Y; Mitsuyama, S; Nishiyama, Y; Toriu, M; Yoneyama, T; Yoshida, K1

Reviews

3 review(s) available for cysteine and guanosine triphosphate

ArticleYear
The GTPase superfamily: a conserved switch for diverse cell functions.
    Nature, 1990, Nov-08, Volume: 348, Issue:6297

    Topics: Animals; Biological Transport; Cysteine; Endocytosis; Exocytosis; GTP Phosphohydrolase-Linked Elongation Factors; GTP-Binding Proteins; Guanosine Triphosphate; Humans; Neurofibromatosis 1; Peptide Elongation Factors; Peptide Initiation Factors; Pheromones; Protein Processing, Post-Translational; Proto-Oncogene Proteins p21(ras); Saccharomyces cerevisiae; Signal Transduction

1990
Role of palmitoylation in RGS protein function.
    Methods in enzymology, 2004, Volume: 389

    Topics: Amino Acid Sequence; Animals; Cell Membrane; Conserved Sequence; Cysteine; GTP Phosphohydrolases; GTP-Binding Protein alpha Subunits, Gi-Go; GTPase-Activating Proteins; Guanosine Triphosphate; Humans; Models, Molecular; Palmitic Acid; Protein Processing, Post-Translational; Protein Structure, Secondary; RGS Proteins; Signal Transduction

2004
Drugging KRAS: current perspectives and state-of-art review.
    Journal of hematology & oncology, 2022, 10-25, Volume: 15, Issue:1

    Topics: Antineoplastic Agents; Cysteine; Guanosine Triphosphate; Humans; Immune Checkpoint Inhibitors; Mutation; Neoplasms; Proto-Oncogene Proteins p21(ras); Tumor Microenvironment

2022

Other Studies

75 other study(ies) available for cysteine and guanosine triphosphate

ArticleYear
Effects of various agents on synaptosomal adenylate cyclase activity in the absence and presence of the boiled supernatant.
    Japanese journal of pharmacology, 1975, Volume: 25, Issue:6

    Topics: Adenine Nucleotides; Adenylyl Cyclases; Animals; Carbachol; Cerebral Cortex; Chloromercuribenzoates; Coenzyme A; Cyclic AMP; Cysteine; Cytosol; Egtazic Acid; Glutathione; Guanosine Triphosphate; Male; Molecular Weight; Rats; Synaptosomes

1975
Phosphoenolpyruvate carboxykinase (guanosine triphosphate) from rat liver cytosol. Separation of homogeneous forms of the enzyme with high and low activity by chromatography on agarose-hexane-guanosine triphosphate.
    Biochemistry, 1978, Dec-12, Volume: 17, Issue:25

    Topics: Adenosine Triphosphate; Animals; Chromatography, Affinity; Cysteine; Cytosol; Dithionitrobenzoic Acid; Guanosine Triphosphate; Kinetics; Ligands; Liver; Phosphoenolpyruvate Carboxykinase (GTP); Rats; Tryptophan; Tyrosine

1978
A vicinal dithiol containing an essential cysteine in phosphoenolpyruvate carboxykinase (guanosine triphosphate) from cytosol of rat liver.
    Biochemistry, 1978, Dec-12, Volume: 17, Issue:25

    Topics: Animals; Arsenic; Binding Sites; Cysteine; Cystine; Cytosol; Disulfides; Dithionitrobenzoic Acid; Guanosine Triphosphate; Kinetics; Liver; Phosphoenolpyruvate Carboxykinase (GTP); Rats

1978
Exogenous modification of nitrovasodilator-induced cyclic GMP formation in human lymphocytes.
    Pharmacology & toxicology, 1992, Volume: 70, Issue:6 Pt 1

    Topics: Chromans; Cyclic GMP; Cysteine; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Activation; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Guanylate Cyclase; Humans; L-Lactate Dehydrogenase; Lymphocytes; Molsidomine; Nitroprusside; Vasodilator Agents

1992
Site-directed mutagenesis of elongation factor Tu. The functional and structural role of residue Cys81.
    European journal of biochemistry, 1992, Sep-01, Volume: 208, Issue:2

    Topics: Binding Sites; Cysteine; Escherichia coli; Guanosine Diphosphate; Guanosine Triphosphate; Hot Temperature; Kinetics; Mutagenesis, Site-Directed; Peptide Biosynthesis; Peptide Elongation Factor Tu; Peptides; Protein Conformation; Protein Denaturation; RNA, Transfer, Amino Acyl; Structure-Activity Relationship

1992
Structural properties of arrestin studied by chemical modification and circular dichroism.
    Biochemistry, 1992, Apr-28, Volume: 31, Issue:16

    Topics: Adenosine Triphosphate; Animals; Antigens; Arrestin; Calcium Chloride; Cattle; Circular Dichroism; Cysteine; Dithionitrobenzoic Acid; Eye Proteins; Fluorides; Guanosine Triphosphate; Kinetics; Potassium; Potassium Chloride; Potassium Compounds; Protein Conformation

1992
Studies of ligand binding to Escherichia coli adenylosuccinate synthetase.
    Archives of biochemistry and biophysics, 1991, Nov-15, Volume: 291, Issue:1

    Topics: Adenosine Monophosphate; Adenylosuccinate Synthase; Binding Sites; Cysteine; Escherichia coli; Fluorescent Dyes; Guanosine Triphosphate; Inosine Monophosphate; Kinetics; Ligands; Naphthalenesulfonates; Protein Conformation; Rhodamines; Spectrometry, Fluorescence

1991
Effects of sulfhydryl-modifying reagents, 3-nitro-2-pyridinesulfenyl compounds, on the coupling between inhibitory receptors and GTP-binding proteins Gi/Go in rat brain membranes.
    Molecular pharmacology, 1990, Volume: 38, Issue:2

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Brain; Cell Membrane; Clonidine; Cysteine; Ethylmaleimide; GTP-Binding Proteins; Guanosine Triphosphate; Indicators and Reagents; Male; Nitro Compounds; Pertussis Toxin; Pyridines; Rats; Receptors, Adrenergic, alpha; Receptors, Serotonin; Sulfhydryl Compounds; Tetrahydronaphthalenes; Virulence Factors, Bordetella

1990
Farnesylated gamma-subunit of photoreceptor G protein indispensable for GTP-binding.
    Nature, 1990, Aug-16, Volume: 346, Issue:6285

    Topics: Amino Acid Sequence; Animals; Binding Sites; Cattle; Chromatography, High Pressure Liquid; Cysteine; Farnesol; Guanosine Triphosphate; Macromolecular Substances; Mass Spectrometry; Methylation; Molecular Sequence Data; Peptide Fragments; Photoreceptor Cells; Serine Endopeptidases; Signal Transduction; Transducin

1990
The uncoupling protein dimer can form a disulfide cross-link between the mobile C-terminal SH groups.
    European journal of biochemistry, 1989, Mar-01, Volume: 180, Issue:1

    Topics: Animals; Binding Sites; Biological Transport; Carrier Proteins; Cricetinae; Cross-Linking Reagents; Cyanogen Bromide; Cysteine; Dipeptides; Disulfides; GTP-Binding Proteins; Guanosine Triphosphate; Ion Channels; Kinetics; Liposomes; Membrane Proteins; Mitochondrial Proteins; Oxidation-Reduction; Phenanthrolines; Trypsin; Uncoupling Agents; Uncoupling Protein 1

1989
Inhibition by forskolin of excitatory amino acid-induced accumulation of cyclic AMP in guinea pig hippocampal slices.
    Journal of neurochemistry, 1988, Volume: 51, Issue:1

    Topics: Adenosine; Amino Acids; Animals; Aspartic Acid; Chlorides; Colforsin; Cyclic AMP; Cysteine; Drug Interactions; Ethylmaleimide; Glutamates; Glutamic Acid; Guanosine Triphosphate; Guinea Pigs; Hippocampus; Histamine; Male; N-Methylaspartate; Neurotransmitter Agents; Veratridine

1988
Location of two cysteines in brain beta 1-tubulin that can be cross-linked after removal of exchangeable GTP.
    Biochimica et biophysica acta, 1987, Mar-18, Volume: 912, Issue:1

    Topics: Amino Acid Sequence; Animals; Binding Sites; Brain; Cattle; Cross-Linking Reagents; Cysteine; Ethylenediamines; Guanosine Triphosphate; Peptide Fragments; Tubulin

1987
The biosynthesis of the nucleoside antibiotics. IX. Purification and properties of guanosine triphosphate 8-formylhydrolase that catalyzes production of formic acid from the ureido carbon of guanosine triphosphate.
    The Journal of biological chemistry, 1971, Nov-25, Volume: 246, Issue:22

    Topics: Adenosine Triphosphate; Amidohydrolases; Ammonium Sulfate; Anti-Bacterial Agents; Benzimidazoles; Chloramphenicol; Chloromercuribenzoates; Chromatography, DEAE-Cellulose; Chromatography, Gel; Cysteine; Depression, Chemical; Dialysis; Edetic Acid; Esterases; Folic Acid; Formates; Guanosine Triphosphate; Inosine Nucleotides; Molecular Weight; Nucleosides; Phosphoric Monoester Hydrolases; Phosphorus Isotopes; Pyrimidines; Pyrroles; Riboflavin; Species Specificity; Streptomyces; Triazines; Xanthopterin

1971
Methionyl residue critical for activity and regulation of bovine liver glutamate dehydrogenase.
    The Journal of biological chemistry, 1973, Nov-10, Volume: 248, Issue:21

    Topics: Adenosine Diphosphate; Alkylation; Allosteric Regulation; Amides; Amino Acids; Animals; Carbon Radioisotopes; Cattle; Cysteine; Drug Synergism; Glutamate Dehydrogenase; Glutamates; Guanosine Triphosphate; Iodoacetates; Ketoglutaric Acids; Kinetics; Liver; Methionine; NAD; Salicylates; Structure-Activity Relationship; Sulfhydryl Compounds

1973
Oxidation of S-carboxymethyl-L-cysteine by glutamate dehydrogenase.
    Physiological chemistry and physics, 1972, Volume: 4, Issue:5

    Topics: Acetates; Adenosine Diphosphate; Animals; Cattle; Cysteine; Glutamate Dehydrogenase; Glutarates; Guanosine Triphosphate; Hydrogen-Ion Concentration; Kinetics; Liver; NAD; Protein Conformation; Thioglycolates

1972
Studies on the partial exchange and overall reactions catalyzed by native and modified arginine kinase from Homarus vulgaris muscle.
    Biochimica et biophysica acta, 1971, Volume: 250, Issue:1

    Topics: Adenine Nucleotides; Alkylation; Animals; Annelida; Arginine; Binding Sites; Carbon Isotopes; Catalysis; Chemical Phenomena; Chemistry; Chromatography, Paper; Creatine Kinase; Cysteine; Dansyl Compounds; Guanosine Triphosphate; Histidine; Kinetics; L-Lactate Dehydrogenase; Lysine; Muscles; Nephropidae; Phosphotransferases; Protein Binding; Pyruvate Kinase; Rabbits

1971
Depalmitoylation of rhodopsin with hydroxylamine.
    Methods in enzymology, 1995, Volume: 250

    Topics: Acylation; Animals; Cattle; Cell Line; Chlorocebus aethiops; Chromatography, Affinity; Cysteine; Guanosine Triphosphate; Hydrogen-Ion Concentration; Hydrolysis; Hydroxylamine; Hydroxylamines; Isotope Labeling; Kinetics; Membrane Proteins; Mutagenesis, Site-Directed; Palmitic Acid; Palmitic Acids; Phosphates; Phosphorus Radioisotopes; Protein Processing, Post-Translational; Radioisotope Dilution Technique; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Rhodopsin; Rod Cell Outer Segment; Transfection; Tritium

1995
Two distinct Raf domains mediate interaction with Ras.
    The Journal of biological chemistry, 1995, Apr-28, Volume: 270, Issue:17

    Topics: 3T3 Cells; Animals; Catalysis; Cell Transformation, Neoplastic; Cysteine; Guanosine Triphosphate; Mice; Protein Binding; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-raf; ras Proteins; Signal Transduction; Xenopus laevis

1995
Mutational analysis of Saccharomyces cerevisiae ARF1.
    The Journal of biological chemistry, 1995, Jan-06, Volume: 270, Issue:1

    Topics: ADP-Ribosylation Factor 1; ADP-Ribosylation Factors; Alleles; Amino Acid Sequence; Aspartic Acid; Cysteine; DNA Mutational Analysis; Genes, Dominant; Genes, Lethal; GTP-Binding Proteins; Guanosine Triphosphate; Molecular Sequence Data; Point Mutation; Protein Binding; Saccharomyces cerevisiae

1995
Identification of a ras-related protein in murine erythroleukemia cells that is a cAMP-dependent protein kinase substrate and is phosphorylated during chemically induced differentiation.
    The Journal of biological chemistry, 1994, Jul-15, Volume: 269, Issue:28

    Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Autoradiography; Blotting, Western; Cell Differentiation; Colforsin; Cyclic AMP-Dependent Protein Kinases; Cysteine; Electrophoresis, Gel, Two-Dimensional; Electrophoresis, Polyacrylamide Gel; GTP-Binding Proteins; Guanosine Triphosphate; Leukemia, Erythroblastic, Acute; Methionine; Mice; Peptide Mapping; Phosphopeptides; Phosphorylation; Proto-Oncogene Proteins; rap GTP-Binding Proteins; Recombinant Proteins; Substrate Specificity; Sulfur Radioisotopes; Transfection; Tumor Cells, Cultured

1994
The cysteine-rich region of raf-1 kinase contains zinc, translocates to liposomes, and is adjacent to a segment that binds GTP-ras.
    The Journal of biological chemistry, 1994, Apr-01, Volume: 269, Issue:13

    Topics: Amino Acid Sequence; Base Sequence; Binding Sites; Binding, Competitive; Calcium; Cell Line; Cell Membrane; Cloning, Molecular; Cysteine; Diglycerides; DNA Primers; Glutathione Transferase; Guanosine Triphosphate; Humans; Kinetics; Liposomes; Molecular Sequence Data; Phorbol Esters; Polymerase Chain Reaction; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-raf; Proto-Oncogene Proteins p21(ras); Recombinant Fusion Proteins; Zinc

1994
G-protein alpha o subunit: mutation of conserved cysteines identifies a subunit contact surface and alters GDP affinity.
    Proceedings of the National Academy of Sciences of the United States of America, 1993, Nov-01, Volume: 90, Issue:21

    Topics: Amino Acid Sequence; Animals; Base Sequence; Binding Sites; Conserved Sequence; Cross-Linking Reagents; Cysteine; DNA Primers; Drosophila; GTP-Binding Proteins; Guanine Nucleotides; Guanosine Diphosphate; Guanosine Triphosphate; Kinetics; Macromolecular Substances; Maleimides; Models, Structural; Molecular Sequence Data; Mutagenesis, Site-Directed; Polymerase Chain Reaction; Protein Structure, Secondary

1993
Identification of reactive vicinal cysteines in Saccharomyces cerevisiae (ATP) and cytosolic rat liver (GTP) phospho enol pyruvate carboxykinases.
    Biochimica et biophysica acta, 1993, Jul-10, Volume: 1164, Issue:2

    Topics: Adenosine Triphosphate; Amino Acid Sequence; Animals; Cysteine; Cytosol; Dithionitrobenzoic Acid; Fluorescent Dyes; Glucosides; Guanosine Triphosphate; Iodoacetamide; Liver; Phosphoenolpyruvate Carboxykinase (GTP); Pyrimidinones; Rats; Saccharomyces cerevisiae

1993
Rapid kinetic measurements of second messenger formation in olfactory cilia from channel catfish.
    The American journal of physiology, 1993, Volume: 264, Issue:4 Pt 1

    Topics: Alanine; Amino Acids; Animals; Cilia; Cyclic AMP; Cyclic GMP; Cysteine; Epithelium; Guanine Nucleotides; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Diphosphate; Guanosine Triphosphate; Ictaluridae; Inositol 1,4,5-Trisphosphate; Kinetics; Olfactory Mucosa; Second Messenger Systems; Thionucleotides

1993
Exchangeable GTP binding site of beta-tubulin. Identification of cysteine 12 as the major site of cross-linking by direct photoaffinity labeling.
    The Journal of biological chemistry, 1993, Jan-05, Volume: 268, Issue:1

    Topics: Affinity Labels; Amino Acid Sequence; Animals; Binding Sites; Brain; Cattle; Chromatography, High Pressure Liquid; Cysteine; Free Radicals; Guanosine Triphosphate; Macromolecular Substances; Molecular Sequence Data; Molecular Weight; Peptide Fragments; Spectrometry, Mass, Fast Atom Bombardment; Thermolysin; Tritium; Trypsin; Tubulin; Ultraviolet Rays

1993
Identification of vicinal thiols of phosphoenolpyruvate carboxykinase (GTP).
    The Journal of biological chemistry, 1993, Jan-25, Volume: 268, Issue:3

    Topics: Alkylation; Amino Acid Sequence; Animals; Azides; Chromatography, High Pressure Liquid; Cysteine; Cystine; Cytosol; Disulfides; Dithionitrobenzoic Acid; Guanosine Triphosphate; Iodoacetates; Iodoacetic Acid; Liver; Molecular Sequence Data; Peptide Fragments; Phosphoenolpyruvate Carboxykinase (GTP); Rats; Sulfhydryl Compounds; Trypsin

1993
Forskolin stimulates detoxification of brefeldin A.
    The Journal of biological chemistry, 1996, Jul-05, Volume: 271, Issue:27

    Topics: Animals; Brefeldin A; Bucladesine; CHO Cells; Colforsin; Cricetinae; Cyclic AMP; Cyclopentanes; Cysteine; Glutathione; Golgi Apparatus; Guanosine Triphosphate; Inactivation, Metabolic; Kinetics; Mycotoxins

1996
Gip-2 codon 179 oncogene mutations: absent in adrenal cortical tumors.
    World journal of surgery, 1996, Volume: 20, Issue:7

    Topics: Adenoma; Adrenal Cortex Neoplasms; Arginine; Base Sequence; Carcinoma; Codon; Cysteine; DNA Restriction Enzymes; GTP-Binding Protein alpha Subunits, Gi-Go; GTP-Binding Proteins; Guanosine Triphosphate; Histidine; Humans; Molecular Sequence Data; Oncogenes; Point Mutation; Polymerase Chain Reaction; Polymorphism, Restriction Fragment Length

1996
Structure and function in rhodopsin. Single cysteine substitution mutants in the cytoplasmic interhelical E-F loop region show position-specific effects in transducin activation.
    Biochemistry, 1996, Sep-24, Volume: 35, Issue:38

    Topics: Amino Acid Sequence; Animals; Cattle; COS Cells; Cysteine; Ethylmaleimide; Fluorescence; Gene Expression; Guanosine Triphosphate; Light; Molecular Sequence Data; Mutagenesis; Recombinant Proteins; Rhodopsin; Rod Opsins; Spectrophotometry; Transducin

1996
Inhibition of capacitative Ca2+ entry into cells by farnesylcysteine analogs.
    Molecular pharmacology, 1996, Volume: 50, Issue:6

    Topics: Affinity Labels; Calcium; Cell Line; Cysteine; Guanosine Triphosphate; Humans; Manganese; Protein Binding; Thapsigargin

1996
Functional domains in nuclear import factor p97 for binding the nuclear localization sequence receptor and the nuclear pore.
    Molecular biology of the cell, 1997, Volume: 8, Issue:6

    Topics: alpha Karyopherins; Binding Sites; Biological Transport; Cell Compartmentation; Cell Nucleus; Cysteine; Guanosine Triphosphate; HeLa Cells; Humans; Mutagenesis, Site-Directed; Nuclear Envelope; Nuclear Proteins; Point Mutation; ran GTP-Binding Protein

1997
Inhibition of growth and p21ras methylation in vascular endothelial cells by homocysteine but not cysteine.
    The Journal of biological chemistry, 1997, Oct-03, Volume: 272, Issue:40

    Topics: Calcium-Calmodulin-Dependent Protein Kinases; Cell Cycle; Cell Division; Cell Membrane; Cells, Cultured; Cysteine; DNA; Endothelium, Vascular; Flow Cytometry; G1 Phase; Guanosine Diphosphate; Guanosine Triphosphate; Homocysteine; Humans; Kinetics; Methylation; Muscle, Smooth, Vascular; Proto-Oncogene Proteins p21(ras); S-Adenosylhomocysteine; Time Factors; Umbilical Veins

1997
Interaction of Ras with Raf (residues 136-189) and related cysteine-rich protein fragments.
    Biochemical Society transactions, 1997, Volume: 25, Issue:3

    Topics: Cysteine; Glutathione Transferase; Guanosine Triphosphate; Isoenzymes; Kinetics; Peptide Fragments; Protein Kinase C; Protein Kinase C-delta; Protein Kinases; Proto-Oncogene Proteins c-raf; ras Proteins; Recombinant Fusion Proteins

1997
Affinity cleavage at the metal-binding site of phosphoenolpyruvate carboxykinase.
    Biochemistry, 1997, Dec-09, Volume: 36, Issue:49

    Topics: Amino Acid Sequence; Animals; Ascorbic Acid; Binding Sites; Chickens; Chromatography, High Pressure Liquid; Cysteine; Free Radical Scavengers; Guanosine Triphosphate; Humans; Hydrolysis; Kinetics; Liver; Metals; Phosphoenolpyruvate Carboxykinase (GTP); Tryptophan

1997
Direct photoaffinity labeling of cysteine-295 of alpha-tubulin by guanosine 5'-triphosphate bound in the nonexchangeable site.
    The Journal of biological chemistry, 1998, Apr-17, Volume: 273, Issue:16

    Topics: Affinity Labels; Amino Acid Sequence; Animals; Brain; Cattle; Cyanogen Bromide; Cysteine; Guanosine Diphosphate; Guanosine Triphosphate; Kinetics; Macromolecular Substances; Molecular Sequence Data; Peptide Fragments; Tubulin

1998
A non-farnesylated Ha-Ras protein can be palmitoylated and trigger potent differentiation and transformation.
    The Journal of biological chemistry, 1999, Jan-15, Volume: 274, Issue:3

    Topics: 3T3 Cells; Animals; Cell Differentiation; Cell Membrane; Cysteine; DNA, Complementary; Guanosine Diphosphate; Guanosine Triphosphate; Mice; Palmitic Acid; PC12 Cells; Protein Prenylation; ras Proteins; Rats; Structure-Activity Relationship; Transfection

1999
Amino-terminal cysteine residues of RGS16 are required for palmitoylation and modulation of Gi- and Gq-mediated signaling.
    The Journal of biological chemistry, 1999, Jun-25, Volume: 274, Issue:26

    Topics: Acylation; Animals; Chromatography, High Pressure Liquid; Consensus Sequence; COS Cells; Cysteine; GTP-Binding Protein alpha Subunits, Gi-Go; GTP-Binding Protein alpha Subunits, Gq-G11; GTP-Binding Proteins; Guanosine Triphosphate; Humans; Palmitates; Phosphoproteins; Proteins; RGS Proteins; Signal Transduction; Transfection

1999
Modulation of the affinity and selectivity of RGS protein interaction with G alpha subunits by a conserved asparagine/serine residue.
    Biochemistry, 1999, Jun-15, Volume: 38, Issue:24

    Topics: Animals; Asparagine; Binding, Competitive; Conserved Sequence; Cysteine; GTP-Binding Protein alpha Subunits, Gi-Go; GTP-Binding Protein alpha Subunits, Gq-G11; GTP-Binding Proteins; GTPase-Activating Proteins; Guanosine Triphosphate; Humans; Hydrolysis; Lysine; Mutagenesis, Site-Directed; Proline; Protein Binding; Proteins; Receptors, Cell Surface; RGS Proteins; Serine

1999
Arabidopsis thaliana 'extra-large GTP-binding protein' (AtXLG1): a new class of G-protein.
    Plant molecular biology, 1999, Volume: 40, Issue:1

    Topics: Amino Acid Sequence; Arabidopsis; Arabidopsis Proteins; Bacterial Proteins; Conserved Sequence; Cysteine; DNA, Complementary; Evolution, Molecular; Genes, Plant; Genomic Library; GTP-Binding Proteins; Guanosine Triphosphate; Membrane Proteins; Molecular Sequence Data; Plant Proteins; Sequence Homology, Amino Acid

1999
Evidence for the carboxyl methylation of nuclear lamin-B in the pancreatic beta cell.
    Biochemical and biophysical research communications, 2000, Feb-16, Volume: 268, Issue:2

    Topics: Animals; Apoptosis; Cell Nucleus; Cysteine; Guanosine Triphosphate; In Vitro Techniques; Islets of Langerhans; Lamin Type B; Lamins; Male; Methylation; Molecular Weight; Nuclear Proteins; Precipitin Tests; Protein Prenylation; Protein Processing, Post-Translational; Rats; Rats, Sprague-Dawley

2000
The Saccharomyces cerevisiae Rheb G-protein is involved in regulating canavanine resistance and arginine uptake.
    The Journal of biological chemistry, 2000, Apr-14, Volume: 275, Issue:15

    Topics: Amino Acid Sequence; Amino Acid Transport Systems; Arginine; Canavanine; Cysteine; Drosophila Proteins; Fungal Proteins; Guanosine Triphosphate; Humans; Membrane Transport Proteins; Molecular Sequence Data; Monomeric GTP-Binding Proteins; Neuropeptides; Protein Prenylation; Ras Homolog Enriched in Brain Protein; Saccharomyces cerevisiae; Schizosaccharomyces pombe Proteins; Structure-Activity Relationship

2000
Fluorescence methods for monitoring interactions of Rab proteins with nucleotides, Rab escort protein, and geranylgeranyltransferase.
    Methods in enzymology, 2001, Volume: 329

    Topics: Alkyl and Aryl Transferases; Animals; Cysteine; Dansyl Compounds; Electrophoresis, Polyacrylamide Gel; Fluorescent Dyes; Fungal Proteins; Guanosine Triphosphate; Indicators and Reagents; Kinetics; Nucleotides; ortho-Aminobenzoates; rab GTP-Binding Proteins; rab7 GTP-Binding Proteins; Spectrometry, Fluorescence

2001
Calcium regulates S-nitrosylation, denitrosylation, and activity of tissue transglutaminase.
    Biochemistry, 2001, Apr-24, Volume: 40, Issue:16

    Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Calcium; Cations, Divalent; Cattle; Cells, Cultured; Cysteine; Endothelium, Vascular; Enzyme Activation; Enzyme Inhibitors; GTP-Binding Proteins; Guanosine Triphosphate; Guinea Pigs; Humans; Kinetics; Mercaptoethanol; Nitric Oxide; Nitroso Compounds; Phosphorylcholine; Platelet Aggregation; Protein Conformation; Protein Glutamine gamma Glutamyltransferase 2; Recombinant Proteins; S-Nitrosothiols; Sphingosine; Transglutaminases

2001
Chemical modification of transducin with iodoacetic acid: transducin-alpha carboxymethylated at Cys(347) allows transducin binding to Light-activated rhodopsin but prevents its release in the presence of GTP.
    Archives of biochemistry and biophysics, 2001, Nov-15, Volume: 395, Issue:2

    Topics: Animals; Cattle; Chromatography, High Pressure Liquid; Cysteine; Guanine; Guanosine Diphosphate; Guanosine Triphosphate; Iodoacetic Acid; Light; Magnetic Resonance Spectroscopy; Models, Molecular; Nucleotides; Peptides; Protein Binding; Protein Conformation; Retina; Rhodopsin; Thiocyanates; Time Factors; Transducin; Trypsin

2001
GTP hydrolysis of cell division protein FtsZ: evidence that the active site is formed by the association of monomers.
    Biochemistry, 2002, Jan-15, Volume: 41, Issue:2

    Topics: Amino Acid Sequence; Bacterial Proteins; Binding Sites; Calcium; Cysteine; Cytoskeletal Proteins; Dose-Response Relationship, Drug; Escherichia coli; Glutamic Acid; GTP Phosphohydrolases; Guanosine Triphosphate; Hydrolysis; Light; Magnesium; Microscopy, Electron; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; Protein Binding; Protein Conformation; Protein Structure, Tertiary; Scattering, Radiation; Sequence Homology, Amino Acid; Time Factors

2002
Biochemical characterization of the Yersinia YopT protease: cleavage site and recognition elements in Rho GTPases.
    Proceedings of the National Academy of Sciences of the United States of America, 2003, Feb-04, Volume: 100, Issue:3

    Topics: Bacterial Proteins; cdc42 GTP-Binding Protein; Cell Line; Chromatography, Thin Layer; Cysteine; Cysteine Endopeptidases; Cytotoxins; Electrophoresis, Polyacrylamide Gel; Glutathione Transferase; Glycine; Guanosine Diphosphate; Guanosine Triphosphate; Humans; Lipid Metabolism; Mass Spectrometry; Plasmids; Protein Binding; Protein Conformation; Protein Prenylation; Protein Structure, Tertiary; Recombinant Proteins; rho GTP-Binding Proteins; rhoA GTP-Binding Protein; Transfection; Yersinia pseudotuberculosis

2003
Palmitoylation regulates regulators of G-protein signaling (RGS) 16 function. I. Mutation of amino-terminal cysteine residues on RGS16 prevents its targeting to lipid rafts and palmitoylation of an internal cysteine residue.
    The Journal of biological chemistry, 2003, May-23, Volume: 278, Issue:21

    Topics: Animals; beta-Cyclodextrins; Caveolin 1; Caveolins; Cell Line; Cell Membrane; COS Cells; Cyclodextrins; Cysteine; Electrophoresis, Polyacrylamide Gel; Enzyme Activation; Glutathione Transferase; GTP Phosphohydrolases; GTP-Binding Protein alpha Subunits, Gi-Go; Guanosine Triphosphate; Heterotrimeric GTP-Binding Proteins; Humans; Immunoblotting; Liver; Male; Membrane Lipids; Mice; Microscopy, Immunoelectron; Models, Molecular; Molecular Structure; Mutagenesis; Palmitic Acid; Proteins; Rats; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Recombinant Fusion Proteins; RGS Proteins; Serotonin; Transfection

2003
Distinct rates of palmitate turnover on membrane-bound cellular and oncogenic H-ras.
    The Journal of biological chemistry, 2003, May-23, Volume: 278, Issue:21

    Topics: 3T3 Cells; Acylation; Animals; Caveolin 1; Caveolins; Cell Membrane; Cysteine; Fibroblasts; Fluorescent Antibody Technique; Genes, ras; Guanosine Diphosphate; Guanosine Triphosphate; Half-Life; Hydrogen-Ion Concentration; Kinetics; Mice; Palmitic Acid; Palmitoyl-CoA Hydrolase; Proto-Oncogene Proteins p21(ras); Sonication; Transfection; Tritium

2003
The GTPase activity and C-terminal cysteine of the Escherichia coli MnmE protein are essential for its tRNA modifying function.
    The Journal of biological chemistry, 2003, Aug-01, Volume: 278, Issue:31

    Topics: Bacterial Proteins; Cysteine; Escherichia coli; GTP Phosphohydrolases; GTP-Binding Proteins; Guanosine Triphosphate; Hydrolysis; Mutagenesis, Site-Directed; Nucleotides; Peptide Fragments; Point Mutation; Protein Conformation; RNA, Transfer; Structure-Activity Relationship

2003
Structure-based analysis of GPCR function: evidence for a novel pentameric assembly between the dimeric leukotriene B4 receptor BLT1 and the G-protein.
    Journal of molecular biology, 2003, Jun-13, Volume: 329, Issue:4

    Topics: Circular Dichroism; Cross-Linking Reagents; Cysteine; Dimerization; Escherichia coli; Fluorescence; GTP-Binding Protein alpha Subunits, Gi-Go; GTP-Binding Proteins; Guanosine Diphosphate; Guanosine Triphosphate; Heterotrimeric GTP-Binding Proteins; Humans; Leukotriene B4; Ligands; Models, Molecular; Neutrons; Protein Conformation; Receptors, Leukotriene B4; Recombinant Proteins; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Structure-Activity Relationship

2003
Mutation of cysteine 214 in Gi1 alpha subunit abolishes its endogenous GTPase activity.
    The Biochemical journal, 2004, May-01, Volume: 379, Issue:Pt 3

    Topics: Adenosine Diphosphate; Adenylyl Cyclases; Alanine; Amino Acid Substitution; Animals; CHO Cells; Colforsin; Cricetinae; Cyclic AMP; Cysteine; GTP-Binding Protein alpha Subunits, Gi-Go; Guanosine Triphosphate; Hydrolysis; Kinetics; Mutation; Pertussis Toxin; Protein Binding; Protein Subunits; RGS Proteins; Thermodynamics; Trypsin; Tryptophan

2004
Characterization of sea urchin transglutaminase, a protein regulated by guanine/adenine nucleotides.
    The Journal of biological chemistry, 2004, Nov-19, Volume: 279, Issue:47

    Topics: Adenine; Adenosine Triphosphatases; Adenosine Triphosphate; Amino Acid Sequence; Animals; Base Sequence; Binding Sites; Catalytic Domain; Cloning, Molecular; Cysteine; DNA, Complementary; Dose-Response Relationship, Drug; Gene Library; Glutathione Transferase; GTP Phosphohydrolases; Guanine; Guanosine Triphosphate; Humans; Hydrolysis; In Situ Hybridization; Kinetics; Molecular Sequence Data; Paracentrotus; Plasmids; Recombinant Fusion Proteins; Sequence Homology, Amino Acid; Transglutaminases

2004
Characterization of mammalian sulfiredoxin and its reactivation of hyperoxidized peroxiredoxin through reduction of cysteine sulfinic acid in the active site to cysteine.
    The Journal of biological chemistry, 2004, Dec-03, Volume: 279, Issue:49

    Topics: Adenosine Triphosphate; Amino Acid Sequence; Animals; Binding Sites; Cell Line, Tumor; Cloning, Molecular; Cysteine; DNA, Complementary; Dose-Response Relationship, Drug; Escherichia coli; Glutathione; Glutathione Transferase; Guanosine Triphosphate; HeLa Cells; Humans; Hydrogen-Ion Concentration; Kinetics; Mice; Models, Chemical; Molecular Sequence Data; Oxidation-Reduction; Oxidoreductases; Oxidoreductases Acting on Sulfur Group Donors; Oxygen; Peroxidases; Peroxiredoxins; Rats; Recombinant Proteins; RNA Interference; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Schizosaccharomyces; Sequence Homology, Amino Acid; Temperature; Thioredoxins; Time Factors; Tissue Distribution

2004
Thiol-disulphide interchange in tubulin: kinetics and the effect on polymerization.
    The Biochemical journal, 2005, Jul-15, Volume: 389, Issue:Pt 2

    Topics: 2,2'-Dipyridyl; Adenosine Triphosphate; Amino Acid Sequence; Biopolymers; Cysteine; Disulfides; Dithionitrobenzoic Acid; Guanosine Diphosphate; Guanosine Triphosphate; Kinetics; Methyl Methanesulfonate; Molecular Structure; Nitrobenzoates; Protein Denaturation; Sulfhydryl Compounds; Tubulin

2005
Rapid in vitro assembly dynamics and subunit turnover of FtsZ demonstrated by fluorescence resonance energy transfer.
    The Journal of biological chemistry, 2005, Jun-10, Volume: 280, Issue:23

    Topics: Biochemistry; Cysteine; Escherichia coli Proteins; Fluorescein; Fluorescence Resonance Energy Transfer; Guanosine Diphosphate; Guanosine Triphosphate; In Vitro Techniques; Kinetics; Magnesium; Microscopy, Electron; Microtubules; Models, Chemical; Mutation; Polymers; Protein Binding; Rhodamines; Time Factors

2005
Differential membrane localization of ERas and Rheb, two Ras-related proteins involved in the phosphatidylinositol 3-kinase/mTOR pathway.
    The Journal of biological chemistry, 2005, Sep-23, Volume: 280, Issue:38

    Topics: Alkyl and Aryl Transferases; Amino Acid Motifs; Amino Acid Sequence; Animals; Cell Membrane; Cells, Cultured; Cysteine; Endopeptidases; Enzyme Inhibitors; Fibroblasts; Golgi Apparatus; Guanosine Diphosphate; Guanosine Triphosphate; Mice; Microscopy, Confocal; Microscopy, Fluorescence; Molecular Sequence Data; Monomeric GTP-Binding Proteins; Mutation; Neuropeptides; Oncogene Protein p21(ras); Palmitic Acids; Phosphatidylinositol 3-Kinases; Plasmids; Protein Kinases; Protein Processing, Post-Translational; Ras Homolog Enriched in Brain Protein; ras Proteins; Sequence Homology, Amino Acid; Subcellular Fractions; TOR Serine-Threonine Kinases

2005
Identification of novel single amino acid changes that result in hyperactivation of the unique GTPase, Rheb, in fission yeast.
    Molecular microbiology, 2005, Volume: 58, Issue:4

    Topics: Amino Acid Sequence; Amino Acid Substitution; Antifungal Agents; Canavanine; Cell Cycle Proteins; Cysteine; Drug Resistance, Fungal; GTP Phosphohydrolases; Guanosine Diphosphate; Guanosine Triphosphate; Molecular Sequence Data; Mutation; Phosphatidylinositol 3-Kinases; Protein Binding; Protein Synthesis Inhibitors; Schizosaccharomyces; Schizosaccharomyces pombe Proteins; Sequence Homology, Amino Acid

2005
Mechanism of allosteric regulation of transglutaminase 2 by GTP.
    Proceedings of the National Academy of Sciences of the United States of America, 2006, Dec-26, Volume: 103, Issue:52

    Topics: Allosteric Regulation; Animals; Arginine; Binding Sites; Cysteine; Disulfides; GTP-Binding Proteins; Guanosine Triphosphate; Hydrogen Bonding; Models, Molecular; Mutation; Protein Binding; Protein Glutamine gamma Glutamyltransferase 2; Protein Structure, Tertiary; Rats; Transglutaminases; Tyrosine; Water

2006
Mutations of Cys-17 and Ala-271 in the human histamine H2 receptor determine the species selectivity of guanidine-type agonists and increase constitutive activity.
    The Journal of pharmacology and experimental therapeutics, 2007, Volume: 321, Issue:3

    Topics: Adenylyl Cyclases; Alanine; Animals; Baculoviridae; Cell Line; Cell Membrane; Cysteine; GTP Phosphohydrolases; GTP-Binding Protein alpha Subunits, Gs; Guanidine; Guanosine Triphosphate; Guinea Pigs; Histamine; Histamine Agonists; Histamine H2 Antagonists; Humans; Mutation, Missense; Receptors, Histamine H2; Recombinant Fusion Proteins; Species Specificity; Spodoptera; Transfection

2007
Crosslinking of translation factor EF-G to proteins of the bacterial ribosome before and after translocation.
    Journal of molecular biology, 2007, May-18, Volume: 368, Issue:5

    Topics: Bacterial Proteins; Cross-Linking Reagents; Cysteine; Escherichia coli; Guanosine Triphosphate; Models, Molecular; Molecular Structure; Peptide Elongation Factor G; Protein Structure, Tertiary; Ribosomal Proteins; Ribosomes; RNA, Messenger; RNA, Transfer; Translocation, Genetic

2007
Redox regulation of Ran GTPase.
    Biochemical and biophysical research communications, 2008, Nov-21, Volume: 376, Issue:3

    Topics: Cysteine; Guanosine Triphosphate; Nitrogen Dioxide; Oxidation-Reduction; Oxidative Stress; ran GTP-Binding Protein

2008
Nucleotide dependent cysteine reactivity of hGBP1 uncovers a domain movement during GTP hydrolysis.
    FEBS letters, 2009, Jun-18, Volume: 583, Issue:12

    Topics: Amino Acid Substitution; Binding Sites; Cysteine; Dithionitrobenzoic Acid; GTP-Binding Proteins; Guanosine Triphosphate; Humans; In Vitro Techniques; Kinetics; Models, Molecular; Mutagenesis, Site-Directed; Protein Structure, Tertiary; Recombinant Proteins; Sulfhydryl Reagents

2009
Coatomer and dimeric ADP ribosylation factor 1 promote distinct steps in membrane scission.
    The Journal of cell biology, 2011, Sep-05, Volume: 194, Issue:5

    Topics: ADP-Ribosylation Factor 1; alpha-Mannosidase; Amino Acid Substitution; Animals; Autoantigens; Coatomer Protein; COP-Coated Vesicles; Cross-Linking Reagents; Cryoelectron Microscopy; Cysteine; Cytoskeletal Proteins; Golgi Apparatus; GTPase-Activating Proteins; Guanosine Triphosphate; HeLa Cells; Humans; Intracellular Membranes; Lipid Bilayers; Membrane Proteins; Microscopy, Electron, Transmission; Microscopy, Fluorescence; Mutation; N-Acetyllactosamine Synthase; Nuclear Proteins; Photochemical Processes; Protein Binding; Protein Multimerization; Rabbits; Rats; Rats, Inbred Strains; Recombinant Fusion Proteins; Transfection; Unilamellar Liposomes

2011
Initiation factor eIF2γ promotes eIF2-GTP-Met-tRNAi(Met) ternary complex binding to the 40S ribosome.
    Nature structural & molecular biology, 2011, Oct-16, Volume: 18, Issue:11

    Topics: Archaeal Proteins; Cysteine; Eukaryotic Initiation Factor-2; Guanosine Triphosphate; Hydroxyl Radical; Models, Molecular; Molecular Sequence Data; Nucleic Acid Conformation; Peptide Elongation Factor Tu; Protein Binding; Protein Structure, Tertiary; Ribosome Subunits, Small, Eukaryotic; RNA, Ribosomal, 18S; RNA, Transfer, Met; Saccharomyces cerevisiae Proteins

2011
A bridging [4Fe-4S] cluster and nucleotide binding are essential for function of the Cfd1-Nbp35 complex as a scaffold in iron-sulfur protein maturation.
    The Journal of biological chemistry, 2012, Apr-06, Volume: 287, Issue:15

    Topics: Adenosine Triphosphatases; Adenosine Triphosphate; Amino Acid Motifs; Amino Acid Substitution; Binding Sites; Conserved Sequence; Coordination Complexes; Cysteine; GTP-Binding Proteins; Guanosine Triphosphate; Iron; Iron-Sulfur Proteins; Mutagenesis, Site-Directed; Oxidation-Reduction; Protein Binding; Protein Interaction Domains and Motifs; Protein Structure, Quaternary; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Sulfur

2012
S-glutathionylation regulates GTP-binding of Rac2.
    Biochemical and biophysical research communications, 2012, Sep-07, Volume: 425, Issue:4

    Topics: Animals; Cysteine; Dithiothreitol; Enzyme Activation; Glutathione; Guanosine Triphosphate; NADP; rac GTP-Binding Proteins; RAC2 GTP-Binding Protein; Recombinant Proteins

2012
Roles of cysteine residues in the inhibition of human glutamate dehydrogenase by palmitoyl-CoA.
    BMB reports, 2012, Volume: 45, Issue:12

    Topics: Allosteric Regulation; Amino Acid Substitution; Binding Sites; Cysteine; Glutamate Dehydrogenase; Guanosine Triphosphate; Humans; Isoenzymes; Palmitoyl Coenzyme A

2012
Evaluating the conformation and binding interface of cap-binding proteins and complexes via ultraviolet photodissociation mass spectrometry.
    Journal of proteome research, 2013, Dec-06, Volume: 12, Issue:12

    Topics: Amino Acid Sequence; Binding Sites; Cysteine; Dithiothreitol; Eukaryotic Initiation Factor-4E; Eukaryotic Initiation Factor-4F; Eukaryotic Initiation Factor-4G; Guanosine Triphosphate; Lysine; Mass Spectrometry; Models, Molecular; Molecular Sequence Data; Plant Proteins; Protein Binding; Protein Structure, Secondary; Protein Structure, Tertiary; Recombinant Proteins; Sequence Alignment; Triticum

2013
K-Ras(G12C) inhibitors allosterically control GTP affinity and effector interactions.
    Nature, 2013, Nov-28, Volume: 503, Issue:7477

    Topics: Allosteric Regulation; Allosteric Site; Apoptosis; Cell Line, Tumor; Crystallography, X-Ray; Cysteine; Drug Discovery; Genes, ras; Guanosine Diphosphate; Guanosine Triphosphate; Humans; Lung Neoplasms; Models, Molecular; Mutant Proteins; Oncogene Protein p21(ras); raf Kinases; Static Electricity; Substrate Specificity

2013
Fe-S cluster biogenesis in isolated mammalian mitochondria: coordinated use of persulfide sulfur and iron and requirements for GTP, NADH, and ATP.
    The Journal of biological chemistry, 2015, Jan-02, Volume: 290, Issue:1

    Topics: Aconitate Hydratase; Adenosine Triphosphate; Animals; Carbon-Sulfur Lyases; Cell Line; Cysteine; Escherichia coli; Ferredoxins; Gene Expression; Guanosine Triphosphate; HeLa Cells; HSP70 Heat-Shock Proteins; Humans; Iron; Mice; Mitochondria; Mitochondrial Proteins; NAD; Neurons; Recombinant Proteins; Sulfides; Sulfur Radioisotopes

2015
Correlation of transducin photoaffinity labeling with the specific formation of intermolecular disulfide linkages in its α-subunit.
    Biochimie, 2015, Volume: 108

    Topics: Animals; Azides; Cattle; Cysteine; Disulfides; Guanosine Triphosphate; Models, Molecular; Photoaffinity Labels; Protein Multimerization; Protein Structure, Quaternary; Protein Subunits; Transducin

2015
Therapeutic Targeting of Nuclear γ-Tubulin in RB1-Negative Tumors.
    Molecular cancer research : MCR, 2015, Volume: 13, Issue:7

    Topics: Acetals; Acyclic Monoterpenes; Animals; Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Cysteine; Dimethyl Fumarate; E2F Transcription Factors; Guanosine Triphosphate; Heterografts; Mice; Microtubules; Monoterpenes; Nuclear Proteins; Retinoblastoma Protein; Tubulin; Tubulin Modulators

2015
Allele-specific inhibitors inactivate mutant KRAS G12C by a trapping mechanism.
    Science (New York, N.Y.), 2016, Feb-05, Volume: 351, Issue:6273

    Topics: Adenocarcinoma; Adenocarcinoma of Lung; Alleles; Antineoplastic Agents; Azetidines; Cell Line, Tumor; Cysteine; Cytidine Diphosphate; Enzyme Inhibitors; Glycine; Guanosine Triphosphate; HEK293 Cells; Humans; Lung Neoplasms; Molecular Targeted Therapy; Mutation; Piperazines; Protein Conformation; Proto-Oncogene Proteins p21(ras); Time Factors

2016
Oxidative stress pathogenically remodels the cardiac myocyte cytoskeleton via structural alterations to the microtubule lattice.
    Developmental cell, 2021, 08-09, Volume: 56, Issue:15

    Topics: Animals; Cell Line; Cysteine; Cytoskeleton; Guanosine Triphosphate; Heart Failure; Microscopy, Fluorescence; Microtubules; Myocytes, Cardiac; Oxidation-Reduction; Oxidative Stress; Rats; Tubulin

2021
Chloroplast translation factor EF-Tu of Arabidopsis thaliana can be inactivated via oxidation of a specific cysteine residue.
    The Biochemical journal, 2023, 05-13, Volume: 480, Issue:5

    Topics: Arabidopsis; Chloroplasts; Cysteine; Escherichia coli; Guanosine Triphosphate; Hydrogen Peroxide; Nucleotides; Oxidation-Reduction; Peptide Elongation Factor Tu; Reactive Oxygen Species; RNA, Transfer, Amino Acyl; Thioredoxins

2023