cysteine has been researched along with guanosine diphosphate in 40 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (7.50) | 18.7374 |
| 1990's | 16 (40.00) | 18.2507 |
| 2000's | 19 (47.50) | 29.6817 |
| 2010's | 2 (5.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Anborgh, PH; Jonák, J; Parmeggiani, A | 1 |
| Cerione, RA; Phillips, WJ | 1 |
| Nicholls, DG; Rial, E | 1 |
| Clark, BF; Jonák, J; Petersen, TE; Rychlík, I | 1 |
| Colman, RF; Marti, C; Tomich, JM | 1 |
| Freeman, KB; Garlid, KD; Modriansky, M; Murdza-Inglis, DL; Patel, HV; Woldegiorgis, G | 1 |
| Neer, EJ; Schmidt, CJ; Thomas, TC | 1 |
| Arechaga, I; Bouillaud, F; Levi-Meyrueis, C; Miroux, B; Prieto, S; Raimbault, S; Rial, E; Ricquier, D; Zaragoza, P | 1 |
| Boekhoff, I; Breer, H; Restrepo, D | 1 |
| Arechaga, I; Bouillaud, F; Fleury, C; González-Barroso, MM; Levi-Meyrueis, C; Raimbault, S; Rial, E; Ricquier, D; Zaragoza, P | 1 |
| Dohlman, HG; Song, J | 1 |
| Ekberg, M; Eklund, H; Eriksson, M; Ramaswamy, S; Regnström, K; Sjöberg, BM; Uhlin, U | 1 |
| Haber, E; Lai, K; Lee, ME; Perrella, MA; Tsai, JC; Wang, H; Yoshizumi, M | 1 |
| Hwang, MC; Hwang, YW; Miller, DL; Sanchez, A | 1 |
| Bochkariov, DE; Dey, D; Jokhadze, GG; Traut, RR | 1 |
| Bai, R; Choe, K; Ewell, JB; Hamel, E; Nguyen, NY | 1 |
| Baker, TL; Booden, MA; Buss, JE; Der, CJ; Punke, SG; Solski, PA | 1 |
| Arshavsky, VY; Liu, Y; Ruoho, AE | 1 |
| Bai, R; Ewell, JB; Hamel, E; Nguyen, NY | 1 |
| Patel, TB; Scholich, K; Yigzaw, Y | 1 |
| Gallet, F; Holmes, EH; Joshi, R; Julien, R; Long, T; Macher, BA; Maftah, A; Nguyen, A; Thomas, S; Yen, TY | 1 |
| Matassova, NB; Peske, F; Rodnina, MV; Savelsbergh, A; Wintermeyer, W | 1 |
| Brune, M; Corrie, JE; Webb, MR | 1 |
| Cai, K; Itoh, Y; Khorana, HG | 1 |
| Bubis, J; Möller, C; Ortiz, JO | 1 |
| Bao, Z; Bowers, KE; Dixon, JE; Fierke, CA; Shao, F; Vacratsis, PO | 1 |
| Baker, TL; Buss, JE; Coloff, JL; Walker, J; Zheng, H | 1 |
| Banères, JL; Parello, J | 1 |
| Hamm, HE; Hubbell, WL; Medkova, M; Preininger, AM; Van Eps, N; Yu, NJ | 1 |
| Bai, R; Copeland, TD; Covell, DG; Hamel, E; Kepler, JA; Nguyen, NY; Pettit, GR; Taylor, GF | 1 |
| Kim, YJ; Pannell, LK; Sackett, DL | 1 |
| Britto, PJ; Knipling, L; McPhie, P; Wolff, J | 1 |
| Chen, Y; Erickson, HP | 1 |
| Nakagawa, M; Takahashi, K; Yamanaka, S; Young, SG | 1 |
| Aspuria, PJ; Comiso, MJ; Deniskin, R; Guo, L; Kato-Stankiewicz, J; Tabancay, AP; Tamanoi, F; Urano, J | 1 |
| Adachi, T; Clavreul, N; Cohen, RA; Ido, Y; Pimental, DR; Schöneich, C | 1 |
| Chatterji, D; China, A; Jain, V; Saleem-Batcha, R | 1 |
| Cook, AC; Ho, C; Malinowski, SA; Miller, KW; Shanmugasundararaj, S; Slater, SJ | 1 |
| Ostrem, JM; Peters, U; Shokat, KM; Sos, ML; Wells, JA | 1 |
| Campbell, SL; Huynh, MV | 1 |
1 review(s) available for cysteine and guanosine diphosphate
| Article | Year |
|---|---|
Getting a Handle on RAS-targeted Therapies: Cysteine Directed Inhibitors.
Topics: Allosteric Regulation; Antineoplastic Agents; Cysteine; Guanosine Diphosphate; Humans; Mutation; Neoplasms; ras Proteins; Small Molecule Libraries | 2016 |
39 other study(ies) available for cysteine and guanosine diphosphate
| Article | Year |
|---|---|
Site-directed mutagenesis of elongation factor Tu. The functional and structural role of residue Cys81.
Topics: Binding Sites; Cysteine; Escherichia coli; Guanosine Diphosphate; Guanosine Triphosphate; Hot Temperature; Kinetics; Mutagenesis, Site-Directed; Peptide Biosynthesis; Peptide Elongation Factor Tu; Peptides; Protein Conformation; Protein Denaturation; RNA, Transfer, Amino Acyl; Structure-Activity Relationship | 1992 |
Labeling of the beta gamma subunit complex of transducin with an environmentally sensitive cysteine reagent. Use of fluorescence spectroscopy to monitor transducin subunit interactions.
Topics: Aluminum; Aluminum Compounds; Anilino Naphthalenesulfonates; Animals; Cattle; Cysteine; Fluorides; Fluorine; GTP Phosphohydrolases; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Diphosphate; Kinetics; Macromolecular Substances; Rhodopsin; Rod Cell Outer Segment; Spectrometry, Fluorescence; Sulfhydryl Reagents; Transducin | 1991 |
Chemical modification of the brown-fat-mitochondrial uncoupling protein with tetranitromethane and N-ethylmaleimide. A cysteine residue is implicated in the nucleotide regulation of anion permeability.
Topics: Adipose Tissue, Brown; Animals; Carrier Proteins; Chlorides; Cricetinae; Cysteine; Ethylmaleimide; Guanosine Diphosphate; Ion Channels; Male; Membrane Proteins; Mesocricetus; Methane; Mitochondria; Mitochondrial Proteins; Permeability; Protein Binding; Protons; Tetranitromethane; Uncoupling Protein 1 | 1986 |
N-Tosyl-L-phenylalanylchloromethane reacts with cysteine 81 in the molecule of elongation factor Tu from Escherichia coli.
Topics: Amino Acid Chloromethyl Ketones; Carbon Radioisotopes; Cysteine; Escherichia coli; Guanosine Diphosphate; Kinetics; Peptide Elongation Factor Tu; Peptide Elongation Factors; Tosylphenylalanyl Chloromethyl Ketone | 1982 |
Modification of two essential cysteines in rabbit muscle pyruvate kinase by the guanine nucleotide analogue 5'[p-(fluorosulfonyl) benzoyl] guanosine.
Topics: Adenosine Diphosphate; Animals; Binding Sites; Cysteine; Fluorescent Dyes; Guanosine; Guanosine Diphosphate; Kinetics; Magnesium; Muscles; Pyruvate Kinase; Rabbits | 1981 |
A single mutation in uncoupling protein of rat brown adipose tissue mitochondria abolishes GDP sensitivity of H+ transport.
Topics: Adipose Tissue, Brown; Animals; Arginine; Biological Transport; Carrier Proteins; Cysteine; Guanosine Diphosphate; Hydrogen; Ion Channels; Membrane Proteins; Mitochondrial Proteins; Mutation; Phenotype; Rats; Recombinant Proteins; Uncoupling Protein 1 | 1994 |
G-protein alpha o subunit: mutation of conserved cysteines identifies a subunit contact surface and alters GDP affinity.
Topics: Amino Acid Sequence; Animals; Base Sequence; Binding Sites; Conserved Sequence; Cross-Linking Reagents; Cysteine; DNA Primers; Drosophila; GTP-Binding Proteins; Guanine Nucleotides; Guanosine Diphosphate; Guanosine Triphosphate; Kinetics; Macromolecular Substances; Maleimides; Models, Structural; Molecular Sequence Data; Mutagenesis, Site-Directed; Polymerase Chain Reaction; Protein Structure, Secondary | 1993 |
Cysteine residues are not essential for uncoupling protein function.
Topics: Base Sequence; Biological Transport; Carrier Proteins; Chlorides; Cysteine; DNA, Complementary; Guanosine Diphosphate; Ion Channels; Membrane Proteins; Mitochondria; Mitochondrial Proteins; Molecular Sequence Data; Mutagenesis, Site-Directed; Oxygen; Permeability; Protons; Saccharomyces cerevisiae; Uncoupling Agents; Uncoupling Protein 1 | 1993 |
Rapid kinetic measurements of second messenger formation in olfactory cilia from channel catfish.
Topics: Alanine; Amino Acids; Animals; Cilia; Cyclic AMP; Cyclic GMP; Cysteine; Epithelium; Guanine Nucleotides; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Diphosphate; Guanosine Triphosphate; Ictaluridae; Inositol 1,4,5-Trisphosphate; Kinetics; Olfactory Mucosa; Second Messenger Systems; Thionucleotides | 1993 |
Activation of the uncoupling protein by fatty acids is modulated by mutations in the C-terminal region of the protein.
Topics: Amino Acid Sequence; Animals; Base Sequence; Carrier Proteins; Cysteine; DNA Primers; Fatty Acids; Galactose; Guanosine Diphosphate; Ion Channels; Kinetics; Membrane Proteins; Mitochondrial Proteins; Molecular Sequence Data; Mutagenesis, Site-Directed; Oxygen Consumption; Palmitates; Peptide Fragments; Permeability; Point Mutation; Recombinant Proteins; Saccharomyces cerevisiae; Uncoupling Protein 1 | 1996 |
Partial constitutive activation of pheromone responses by a palmitoylation-site mutant of a G protein alpha subunit in yeast.
Topics: Cell Membrane; Cysteine; Esters; Fungal Proteins; GTP-Binding Protein alpha Subunits; GTP-Binding Protein alpha Subunits, Gq-G11; GTP-Binding Proteins; Guanosine Diphosphate; Heterotrimeric GTP-Binding Proteins; Membrane Proteins; Mutagenesis; Palmitic Acid; Pheromones; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Signal Transduction; Sulfhydryl Compounds | 1996 |
Binding of allosteric effectors to ribonucleotide reductase protein R1: reduction of active-site cysteines promotes substrate binding.
Topics: Allosteric Regulation; Amino Acid Sequence; Binding Sites; Conserved Sequence; Crystallography, X-Ray; Cysteine; Dimerization; Guanosine Diphosphate; Models, Chemical; Models, Molecular; Molecular Sequence Data; Oxidation-Reduction; Ribonucleotide Reductases; Sequence Alignment; Substrate Specificity; Thymine Nucleotides | 1997 |
Inhibition of growth and p21ras methylation in vascular endothelial cells by homocysteine but not cysteine.
Topics: Calcium-Calmodulin-Dependent Protein Kinases; Cell Cycle; Cell Division; Cell Membrane; Cells, Cultured; Cysteine; DNA; Endothelium, Vascular; Flow Cytometry; G1 Phase; Guanosine Diphosphate; Guanosine Triphosphate; Homocysteine; Humans; Kinetics; Methylation; Muscle, Smooth, Vascular; Proto-Oncogene Proteins p21(ras); S-Adenosylhomocysteine; Time Factors; Umbilical Veins | 1997 |
The role of cysteinyl residues in the activity of bacterial elongation factor Ts, a guanosine nucleotide dissociation protein.
Topics: Amino Acid Substitution; Cloning, Molecular; Cysteine; Escherichia coli; Glycine; Guanosine Diphosphate; Kinetics; Mutagenesis, Site-Directed; Peptide Elongation Factors; Protein Conformation; Recombinant Proteins; Sequence Tagged Sites; Serine | 1997 |
Cross-linking of selected residues in the N- and C-terminal domains of Escherichia coli protein L7/L12 to other ribosomal proteins and the effect of elongation factor Tu.
Topics: Amino Acid Substitution; Binding Sites; Centrifugation, Density Gradient; Crystallography, X-Ray; Cysteine; Escherichia coli; Escherichia coli Proteins; Guanosine Diphosphate; Models, Molecular; Mutagenesis, Site-Directed; Peptide Elongation Factor Tu; Protein Conformation; Pyridones; Ribosomal Proteins; Structure-Activity Relationship | 1998 |
Direct photoaffinity labeling of cysteine-295 of alpha-tubulin by guanosine 5'-triphosphate bound in the nonexchangeable site.
Topics: Affinity Labels; Amino Acid Sequence; Animals; Brain; Cattle; Cyanogen Bromide; Cysteine; Guanosine Diphosphate; Guanosine Triphosphate; Kinetics; Macromolecular Substances; Molecular Sequence Data; Peptide Fragments; Tubulin | 1998 |
A non-farnesylated Ha-Ras protein can be palmitoylated and trigger potent differentiation and transformation.
Topics: 3T3 Cells; Animals; Cell Differentiation; Cell Membrane; Cysteine; DNA, Complementary; Guanosine Diphosphate; Guanosine Triphosphate; Mice; Palmitic Acid; PC12 Cells; Protein Prenylation; ras Proteins; Rats; Structure-Activity Relationship; Transfection | 1999 |
Interaction sites of the C-terminal region of the cGMP phosphodiesterase inhibitory subunit with the GDP-bound transducin alpha-subunit.
Topics: 3',5'-Cyclic-GMP Phosphodiesterases; Animals; Cattle; Cyanogen Bromide; Cyclic Nucleotide Phosphodiesterases, Type 6; Cysteine; Disulfides; Enzyme Activation; Guanosine Diphosphate; Hydroxylamine; Iodine Radioisotopes; Models, Chemical; Models, Molecular; Protein Binding; Transducin | 1999 |
Direct photoaffinity labeling of cysteine 211 or a nearby amino acid residue of beta-tubulin by guanosine 5'-diphosphate bound in the exchangeable site.
Topics: Amino Acid Sequence; Binding Sites; Chromatography, Liquid; Cysteine; Guanosine Diphosphate; Molecular Sequence Data; Photoaffinity Labels; Tubulin | 1999 |
Cysteine 3 is not the site of in vitro palmitoylation on G(salpha).
Topics: Acylation; Cell-Free System; Cysteine; GTP-Binding Protein alpha Subunits, Gs; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Diphosphate; Mutation; Palmitic Acid; Palmitoyl Coenzyme A; Protein Conformation; Protein Processing, Post-Translational | 2000 |
Human alpha 1,3/4 fucosyltransferases. Characterization of highly conserved cysteine residues and N-linked glycosylation sites.
Topics: Amino Acid Sequence; Amino Acid Substitution; Animals; Conserved Sequence; COS Cells; Cysteine; Disulfides; Fucosyltransferases; Glycosylation; Guanosine Diphosphate; Humans; Kinetics; Mass Spectrometry; Mutagenesis, Site-Directed; Oligosaccharides; Peptide Fragments; Recombinant Proteins; Transfection | 2000 |
Conformationally restricted elongation factor G retains GTPase activity but is inactive in translocation on the ribosome.
Topics: Amino Acid Substitution; Cross-Linking Reagents; Cysteine; Escherichia coli; GTP Phosphohydrolases; Guanosine Diphosphate; Kinetics; Models, Molecular; Mutagenesis, Site-Directed; Peptide Elongation Factor G; Protein Conformation; Recombinant Proteins; Ribosomes; RNA, Transfer; Thermus thermophilus | 2000 |
A fluorescent sensor of the phosphorylation state of nucleoside diphosphate kinase and its use to monitor nucleoside diphosphate concentrations in real time.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Aspartic Acid; Binding Sites; Coumarins; Cysteine; Fluorescent Dyes; Guanosine Diphosphate; Humans; Kinetics; Mass Spectrometry; Mutagenesis, Site-Directed; Myosin Subfragments; Myxococcus xanthus; Nucleoside-Diphosphate Kinase; Phosphorylation; Purine Nucleotides; Rabbits; rho GTP-Binding Proteins; Solutions; Spectrometry, Fluorescence | 2001 |
Mapping of contact sites in complex formation between transducin and light-activated rhodopsin by covalent crosslinking: use of a photoactivatable reagent.
Topics: Amino Acid Sequence; Animals; Azides; Binding Sites; Cattle; COS Cells; Cross-Linking Reagents; Cysteine; Disulfides; Dithiothreitol; Ethylmaleimide; Guanosine Diphosphate; Light; Lysine; Maleimides; Models, Molecular; Molecular Sequence Data; Mutation; Photolysis; Protein Binding; Protein Structure, Secondary; Pyridines; Rhodopsin; Sepharose; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Transducin; Trypsin; Ultraviolet Rays | 2001 |
Chemical modification of transducin with iodoacetic acid: transducin-alpha carboxymethylated at Cys(347) allows transducin binding to Light-activated rhodopsin but prevents its release in the presence of GTP.
Topics: Animals; Cattle; Chromatography, High Pressure Liquid; Cysteine; Guanine; Guanosine Diphosphate; Guanosine Triphosphate; Iodoacetic Acid; Light; Magnetic Resonance Spectroscopy; Models, Molecular; Nucleotides; Peptides; Protein Binding; Protein Conformation; Retina; Rhodopsin; Thiocyanates; Time Factors; Transducin; Trypsin | 2001 |
Biochemical characterization of the Yersinia YopT protease: cleavage site and recognition elements in Rho GTPases.
Topics: Bacterial Proteins; cdc42 GTP-Binding Protein; Cell Line; Chromatography, Thin Layer; Cysteine; Cysteine Endopeptidases; Cytotoxins; Electrophoresis, Polyacrylamide Gel; Glutathione Transferase; Glycine; Guanosine Diphosphate; Guanosine Triphosphate; Humans; Lipid Metabolism; Mass Spectrometry; Plasmids; Protein Binding; Protein Conformation; Protein Prenylation; Protein Structure, Tertiary; Recombinant Proteins; rho GTP-Binding Proteins; rhoA GTP-Binding Protein; Transfection; Yersinia pseudotuberculosis | 2003 |
Distinct rates of palmitate turnover on membrane-bound cellular and oncogenic H-ras.
Topics: 3T3 Cells; Acylation; Animals; Caveolin 1; Caveolins; Cell Membrane; Cysteine; Fibroblasts; Fluorescent Antibody Technique; Genes, ras; Guanosine Diphosphate; Guanosine Triphosphate; Half-Life; Hydrogen-Ion Concentration; Kinetics; Mice; Palmitic Acid; Palmitoyl-CoA Hydrolase; Proto-Oncogene Proteins p21(ras); Sonication; Transfection; Tritium | 2003 |
Structure-based analysis of GPCR function: evidence for a novel pentameric assembly between the dimeric leukotriene B4 receptor BLT1 and the G-protein.
Topics: Circular Dichroism; Cross-Linking Reagents; Cysteine; Dimerization; Escherichia coli; Fluorescence; GTP-Binding Protein alpha Subunits, Gi-Go; GTP-Binding Proteins; Guanosine Diphosphate; Guanosine Triphosphate; Heterotrimeric GTP-Binding Proteins; Humans; Leukotriene B4; Ligands; Models, Molecular; Neutrons; Protein Conformation; Receptors, Leukotriene B4; Recombinant Proteins; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Structure-Activity Relationship | 2003 |
The myristoylated amino terminus of Galpha(i)(1) plays a critical role in the structure and function of Galpha(i)(1) subunits in solution.
Topics: Aluminum Compounds; Cysteine; DNA Primers; Electron Spin Resonance Spectroscopy; Electrophoresis, Polyacrylamide Gel; Fluorescent Dyes; Fluorides; GTP-Binding Protein alpha Subunits, Gi-Go; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Diphosphate; Humans; Models, Molecular; Mutagenesis, Site-Directed; Myristic Acid; Protein Binding; Protein Conformation; Spin Labels; Structure-Activity Relationship; Sulfhydryl Compounds | 2003 |
Direct photoaffinity labeling by dolastatin 10 of the amino-terminal peptide of beta-tubulin containing cysteine 12.
Topics: Animals; Antineoplastic Agents; Binding Sites; Brain; Cattle; Computer Simulation; Cysteine; Depsipeptides; Dithiothreitol; Electrophoresis, Polyacrylamide Gel; Guanosine Diphosphate; Kinetics; Ligands; Light; Models, Chemical; Models, Molecular; Oligopeptides; Peptides; Peptides, Cyclic; Photoaffinity Labels; Protein Binding; Protein Conformation; Protein Structure, Tertiary; Thiazoles; Time Factors; Tubulin; Ultraviolet Rays | 2004 |
Mass spectrometric measurement of differential reactivity of cysteine to localize protein-ligand binding sites. Application to tubulin-binding drugs.
Topics: Alkylating Agents; Amino Acid Sequence; Binding Sites; Chromatography, High Pressure Liquid; Cysteine; Drug Delivery Systems; Guanosine Diphosphate; Ligands; Mass Spectrometry; Molecular Sequence Data; Pharmaceutical Preparations; Protein Binding; Protein Conformation; Substrate Specificity; Tubulin | 2004 |
Thiol-disulphide interchange in tubulin: kinetics and the effect on polymerization.
Topics: 2,2'-Dipyridyl; Adenosine Triphosphate; Amino Acid Sequence; Biopolymers; Cysteine; Disulfides; Dithionitrobenzoic Acid; Guanosine Diphosphate; Guanosine Triphosphate; Kinetics; Methyl Methanesulfonate; Molecular Structure; Nitrobenzoates; Protein Denaturation; Sulfhydryl Compounds; Tubulin | 2005 |
Rapid in vitro assembly dynamics and subunit turnover of FtsZ demonstrated by fluorescence resonance energy transfer.
Topics: Biochemistry; Cysteine; Escherichia coli Proteins; Fluorescein; Fluorescence Resonance Energy Transfer; Guanosine Diphosphate; Guanosine Triphosphate; In Vitro Techniques; Kinetics; Magnesium; Microscopy, Electron; Microtubules; Models, Chemical; Mutation; Polymers; Protein Binding; Rhodamines; Time Factors | 2005 |
Differential membrane localization of ERas and Rheb, two Ras-related proteins involved in the phosphatidylinositol 3-kinase/mTOR pathway.
Topics: Alkyl and Aryl Transferases; Amino Acid Motifs; Amino Acid Sequence; Animals; Cell Membrane; Cells, Cultured; Cysteine; Endopeptidases; Enzyme Inhibitors; Fibroblasts; Golgi Apparatus; Guanosine Diphosphate; Guanosine Triphosphate; Mice; Microscopy, Confocal; Microscopy, Fluorescence; Molecular Sequence Data; Monomeric GTP-Binding Proteins; Mutation; Neuropeptides; Oncogene Protein p21(ras); Palmitic Acids; Phosphatidylinositol 3-Kinases; Plasmids; Protein Kinases; Protein Processing, Post-Translational; Ras Homolog Enriched in Brain Protein; ras Proteins; Sequence Homology, Amino Acid; Subcellular Fractions; TOR Serine-Threonine Kinases | 2005 |
Identification of novel single amino acid changes that result in hyperactivation of the unique GTPase, Rheb, in fission yeast.
Topics: Amino Acid Sequence; Amino Acid Substitution; Antifungal Agents; Canavanine; Cell Cycle Proteins; Cysteine; Drug Resistance, Fungal; GTP Phosphohydrolases; Guanosine Diphosphate; Guanosine Triphosphate; Molecular Sequence Data; Mutation; Phosphatidylinositol 3-Kinases; Protein Binding; Protein Synthesis Inhibitors; Schizosaccharomyces; Schizosaccharomyces pombe Proteins; Sequence Homology, Amino Acid | 2005 |
S-glutathiolation by peroxynitrite of p21ras at cysteine-118 mediates its direct activation and downstream signaling in endothelial cells.
Topics: Acetophenones; Androstadienes; Animals; Aorta; Butadienes; Cattle; Cells, Cultured; Cysteine; Endothelial Cells; Endothelium, Vascular; Enzyme Activation; Extracellular Signal-Regulated MAP Kinases; Glutathione; Guanosine Diphosphate; Lipoproteins, LDL; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitriles; Oxidation-Reduction; Peroxynitrous Acid; Phosphorylation; Protein Processing, Post-Translational; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins p21(ras); Recombinant Fusion Proteins; Signal Transduction; Wortmannin | 2006 |
Molecular dissection of the mycobacterial stringent response protein Rel.
Topics: Amino Acid Sequence; Circular Dichroism; Conserved Sequence; Cysteine; Databases, Protein; Guanosine Diphosphate; Hydrolysis; Ligases; Molecular Sequence Data; Mutation; Mycobacterium smegmatis; Protein Structure, Tertiary; RNA, Transfer; Sequence Deletion; Sequence Homology, Amino Acid; Serine | 2006 |
Interaction of anesthetics with the Rho GTPase regulator Rho GDP dissociation inhibitor.
Topics: Allosteric Regulation; Anesthetics, Inhalation; Animals; Binding Sites; Cell Line; Cysteine; Diterpenes; Guanine Nucleotide Dissociation Inhibitors; Guanosine Diphosphate; Halothane; Humans; Hydrophobic and Hydrophilic Interactions; rho-Specific Guanine Nucleotide Dissociation Inhibitors; rhoA GTP-Binding Protein; Spodoptera | 2008 |
K-Ras(G12C) inhibitors allosterically control GTP affinity and effector interactions.
Topics: Allosteric Regulation; Allosteric Site; Apoptosis; Cell Line, Tumor; Crystallography, X-Ray; Cysteine; Drug Discovery; Genes, ras; Guanosine Diphosphate; Guanosine Triphosphate; Humans; Lung Neoplasms; Models, Molecular; Mutant Proteins; Oncogene Protein p21(ras); raf Kinases; Static Electricity; Substrate Specificity | 2013 |