Compounds > cysteine

cysteine and gefitinib

cysteine has been researched along with gefitinib in 6 studies

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (16.67)29.6817
2010's4 (66.67)24.3611
2020's1 (16.67)2.80

Authors

AuthorsStudies
Angelo, LS; Gong, J; Kohanim, S; Kurzrock, R; Yang, DJ1
Cao, XJ; Garcia, BA; Kharbanda, A; Runkle, KB; Stypulkowski, E; Wang, W; Witze, ES1
Kharbanda, A; Runkle, K; Wang, W; Witze, ES1
Alfieri, R; Bonelli, M; Bozza, N; Callegari, D; Castelli, R; Cavazzoni, A; Digiacomo, G; Ferlenghi, F; Fumarola, C; Lodola, A; Mor, M; Petronini, PG; Rivara, S; Silva, C; Vacondio, F1
Kim, KS; Liu, W; Prakash, A; Zhang, C; Zhu, N1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1

Reviews

1 review(s) available for cysteine and gefitinib

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Other Studies

5 other study(ies) available for cysteine and gefitinib

ArticleYear
Molecular imaging of gefitinib activity in an epidermal growth factor receptor (EGFR)-bearing xenograft model.
    Cancer biology & therapy, 2009, Volume: 8, Issue:23

    Topics: Animals; Apoptosis; Blotting, Western; Cell Line, Tumor; Cysteine; ErbB Receptors; Female; Flow Cytometry; Gefitinib; Humans; Immunoprecipitation; Indium Radioisotopes; Mice; Mice, Nude; Molecular Imaging; Neoplasms, Glandular and Epithelial; Phosphorylation; Protein Kinase Inhibitors; Quinazolines; Radionuclide Imaging; Technetium; Tissue Distribution; Xenograft Model Antitumor Assays

2009
Inhibition of DHHC20-Mediated EGFR Palmitoylation Creates a Dependence on EGFR Signaling.
    Molecular cell, 2016, 05-05, Volume: 62, Issue:3

    Topics: Acyltransferases; Animals; Antineoplastic Agents; Breast Neoplasms; Cell Death; Cell Line, Tumor; Cell Movement; Cell Proliferation; Cysteine; Endocytosis; Epidermal Growth Factor; ErbB Receptors; Gefitinib; GRB2 Adaptor Protein; HEK293 Cells; Humans; Lipoylation; Mass Spectrometry; Mice; Mutation; NIH 3T3 Cells; Protein Conformation; Protein Kinase Inhibitors; Protein Processing, Post-Translational; Protein Transport; Proteolysis; Quinazolines; RNA Interference; Signal Transduction; Structure-Activity Relationship; Transfection

2016
Induced sensitivity to EGFR inhibitors is mediated by palmitoylated cysteine 1025 of EGFR and requires oncogenic Kras.
    Biochemical and biophysical research communications, 2017, 11-04, Volume: 493, Issue:1

    Topics: Antineoplastic Agents; Apoptosis; Cocarcinogenesis; Cysteine; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; ErbB Receptors; Gefitinib; Humans; Lipoylation; MCF-7 Cells; Membrane Proteins; Mutation; Neoplasms, Experimental; Proto-Oncogene Proteins p21(ras); Quinazolines

2017
Balancing reactivity and antitumor activity: heteroarylthioacetamide derivatives as potent and time-dependent inhibitors of EGFR.
    European journal of medicinal chemistry, 2019, Jan-15, Volume: 162

    Topics: A549 Cells; Acetamides; Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Cysteine; ErbB Receptors; Gefitinib; Humans; Lung Neoplasms; Phosphorylation; Thioacetamide

2019
Targeting E. coli invasion of the blood-brain barrier for investigating the pathogenesis and therapeutic development of E. coli meningitis.
    Cellular microbiology, 2020, Volume: 22, Issue:10

    Topics: Acetates; Animals; Anti-Bacterial Agents; Blood-Brain Barrier; Brain; Ceftriaxone; Cells, Cultured; Cyclopropanes; Cysteine; Drug Therapy, Combination; Endothelial Cells; ErbB Receptors; Escherichia coli; Female; Gefitinib; Humans; Infant, Newborn; Leukotriene Antagonists; Leukotrienes; Male; Meningitis, Escherichia coli; Mice; Permeability; Phospholipases A2, Cytosolic; Quinolines; Sphingosine-1-Phosphate Receptors; Sulfides

2020