cysteine has been researched along with gamma-aminobutyric acid in 79 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 16 (20.25) | 18.7374 |
| 1990's | 13 (16.46) | 18.2507 |
| 2000's | 26 (32.91) | 29.6817 |
| 2010's | 14 (17.72) | 24.3611 |
| 2020's | 10 (12.66) | 2.80 |
| Authors | Studies |
|---|---|
| Gaull, GE; Ingoglia, NA; Lindquist, TD; Sturman, JA | 1 |
| Sato, M; Sato, T; Sawada, M | 1 |
| Edmondson, F; Horton, R; Meldrum, B; Sawaya, C | 1 |
| Kuriyama, K; Yoneda, Y | 1 |
| Ho, CK; Kern, HL; Ostrove, SA | 1 |
| Bayón, A; Possani, LD; Tapia, R | 1 |
| Fonnum, F; Lund-Karlsen, R; Malthe-Sørenssen, D; Oddan, E | 1 |
| Cuénod, M; Do, KQ; Gähwiler, BH; Jiang, ZP; Klancnik, JM | 1 |
| Dunlop, J; Grieve, A; Griffiths, R; Schousboe, A | 1 |
| Ferko, AP | 1 |
| Eimerl, S; Minc-Golomb, D; Schramm, M | 1 |
| Giles, D; Usherwood, PN | 1 |
| Baba, A; Iwata, H; Morimoto, H | 1 |
| De La Rosa, J; Hirschberger, LL; Stipanuk, MH | 1 |
| Baba, A | 1 |
| Colombo-Zefinetti, G; Pinelli, A; Tofanetti, O; Trivulzio, S | 1 |
| Baba, A; Iwata, H; Mizuo, H; Okumura, S | 1 |
| Furukawa, T; Morishita, H; Ono, N; Tokunaga, T | 1 |
| Ida, S; Kuriyama, K; Nishimura, C | 1 |
| Baba, A; Iwata, H | 1 |
| Amin, J; Dickerson, IM; Weiss, DS | 1 |
| Yadid, G; Youdim, MB; Zinder, O | 1 |
| Abbas, AK; Jardemark, K; Lehmann, A; Sandberg, M; Weber, SG | 1 |
| Garcia, Y; Jaffe, EH | 1 |
| Cao, Y; Lester, HA; Mager, S; Yu, N | 1 |
| Hu, LA; King, SC | 2 |
| Boileau, AJ; Czajkowski, C; Davis, AF; Evers, AR | 1 |
| Akabas, MH; Williams, DB | 1 |
| Konev, SV; Mongin, AA; Nedvetsky, PI; Petrenko, SV; Rakovich, AA | 1 |
| Czajkowski, C; Wagner, DA | 1 |
| Czajkowski, C; Teissére, JA | 1 |
| Ahmadi, H; Croucher, MJ; Harris, JR; Lawrence, V; Thomas, LS | 1 |
| Boileau, AJ; Czajkowski, C; Newell, JG | 1 |
| Akabas, MH; Bera, AK; Chatav, M | 1 |
| Brown-Istvan, L; King, SC | 1 |
| Bennett, ER; Kanner, BI; Zhou, Y | 1 |
| Ataide, SF; Ibba, M; Levengood, J; Roy, H | 1 |
| Filippova, N; Weiss, DS; Wotring, VE | 1 |
| Kittler, JT; Moss, SJ; Rathenberg, J | 1 |
| Aguayo, LG; Aranda, M; Hallier, E; Morales, B; Müller, M; Oyarce, M; Pancetti, F; Parodi, J; Westphal, G; Zeise, ML | 1 |
| Akabas, MH; Horenstein, J; Riegelhaupt, P | 1 |
| Chang, Y; Davis, D; Sedelnikova, A; Smith, CD; Weiss, DS; Zakharkin, SO | 1 |
| Kanner, BI; Zhou, Y | 1 |
| Kanner, BI; Zhou, Y; Zomot, E | 1 |
| Dougherty, DA; Hanek, AP; Lester, HA; Wang, J; Xiu, X | 1 |
| Bossi, E; Castagna, M; Mari, SA; Perego, C; Peres, A; Sacchi, VF; Santacroce, M; Soragna, A | 1 |
| Akabas, MH; Bali, M | 1 |
| Abbas, AK; Sandberg, M; Tranberg, M; Weber, SG; Wigström, H; Xia, W | 1 |
| Baur, R; Sigel, E | 1 |
| Czajkowski, C; Hanson, SM | 1 |
| Ilg, T; Jaeger, M; Rothacker, B | 1 |
| Chang, Y; Xue, F; Zhang, J | 1 |
| Ben-Yona, A; Kanner, BI | 1 |
| Baur, R; Charon, S; Goeldner, M; Sigel, E; Tan, KR | 1 |
| Arai, H; Doi, N; Hatta, K; Nakamura, H; Nakanishi, A; Nishioka, K; Usui, C | 1 |
| Borghese, CM; Harris, RA; McCracken, ML; Trudell, JR | 1 |
| Ashby, JA; Dougherty, DA; Lummis, SC; McGonigle, I | 1 |
| Harris, RA; Howard, RJ; Johnson, WD; Trudell, JR | 1 |
| Aoyama, K; Kikuchi-Utsumi, K; Kinoshita, C; Kiyonari, H; Matsumura, N; Nakaki, T; Shioi, G; Tanaka, K; Wang, F; Watabe, M | 1 |
| Anderson, CM; Choi, YE; Eskandari, S; Maestas, MJ; Omoto, JJ; Rahnama-Vaghef, A; Salto, G; Sanchez, RV | 1 |
| Borghese, CM; Harris, RA; Hicks, JA; Lapid, DJ; Trudell, JR | 1 |
| Dejanovic, B; Schwarz, G | 1 |
| Dejanovic, B; Ebert, S; Lamkemeyer, T; Lüscher, B; Meier, JC; Neuser, F; Schwarz, G; Semtner, M | 1 |
| Dayan, O; Hilwi, M; Kanner, BI | 1 |
| Duke, RK; Hinton, T; Johnston, GA; Ng, CC | 1 |
| Beltrán González, AN; Calvo, DJ; Vicentini, F | 1 |
| Chaiyen, P; Maenpuen, S; Munkajohnpong, P; Phonbuppha, J; Tinikul, R | 1 |
| Shah, NP; Xiao, T | 1 |
| Akk, G; Burbridge, AB; Germann, AL; Pierce, SR | 1 |
| Shah, NP; Tun, HM; Xiao, T; Zhang, D | 1 |
| Chen, X; Ge, T; He, Z; Wang, J; Yuan, H; Zhang, L | 1 |
| Chen, YY; Chou, YH; Liu, MN; Yang, BH; Yang, KC | 1 |
| Dietz, KJ; García-Caparrós, P; Kumar, V; Persicke, M; Vogelsang, L; Wirtz, M | 1 |
| Li, X; Liu, P; Lv, M; Shi, Z; Tang, X; Wang, F; Wu, H; Zhang, K; Zhang, M; Zheng, Y | 1 |
| Kailasa, SK; Park, TJ | 1 |
| Deng, Q; Du, Y; Liu, H; Luo, X; Pu, J; Tang, X; Wang, M; Wang, Y; Zhang, H | 1 |
| Astudillo, A; Bretones, G; Engedal, N; Fueyo, A; López-Otín, C; Mariño, G; Martínez-García, GG; Mayoral, P; Prieto-Lloret, J; Suárez, MF; Sveen, C; Tamargo-Gómez, I | 1 |
| Brandsch, M; Gebauer, S; Laug, L; Schäfer, S; Thondorf, I; Voigt, V; Zebisch, K | 1 |
3 review(s) available for cysteine and gamma-aminobutyric acid
| Article | Year |
|---|---|
Neurochemical characterization of cysteine sulfinic acid, an excitatory amino acid, in hippocampus.
Topics: Amino Acids; Animals; Anti-Anxiety Agents; Benzodiazepines; Brain Chemistry; Cyclic AMP; Cysteine; gamma-Aminobutyric Acid; Hippocampus; Humans; Neurotransmitter Agents | 1987 |
Central and peripheral effects of sulfur amino acids: antagonism against central effect of angiotensin.
Topics: Amino Acids, Sulfur; Angiotensin II; Animals; Blood Pressure; Calcium; Cysteic Acid; Cysteine; Electric Stimulation; gamma-Aminobutyric Acid; Methionine; Muscle Contraction; Renin-Angiotensin System; Sympathetic Nervous System; Synaptic Transmission; Taurine | 1983 |
Biosynthesis of taurine in frog retina--differential effects of physiological light and gamma-ray irradiation.
Topics: Amino Acids; Animals; Cysteine; Darkness; Dopamine; gamma-Aminobutyric Acid; Kainic Acid; Kinetics; Photic Stimulation; Rana catesbeiana; Retina; Taurine | 1983 |
76 other study(ies) available for cysteine and gamma-aminobutyric acid
| Article | Year |
|---|---|
Axonal migration of taurine in the goldfish visual system.
Topics: Animals; Axonal Transport; Cysteine; gamma-Aminobutyric Acid; Goldfish; Optic Nerve; Retina; Superior Colliculi; Taurine | 1976 |
Effects of disulfide bond reduction on the excitatory and inhibitory postsynaptic responses of Aplysia ganglion cells.
Topics: Acetylcholine; Acetylcholinesterase; Affinity Labels; Animals; Cholinergic Fibers; Cysteine; Cystine; Disulfides; Dithionitrobenzoic Acid; Dithiothreitol; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; Ganglia; Mollusca; Neural Conduction; Neural Inhibition; Nitrobenzoates; Oxidation-Reduction; Receptors, Dopamine; Receptors, Muscarinic; Receptors, Neurotransmitter; Receptors, Nicotinic; Structure-Activity Relationship | 1976 |
Convulsant drug action on GABA and taurine synthesis.
Topics: Animals; Brain; Carboxy-Lyases; Convulsants; Cysteine; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Mice; Taurine | 1979 |
A comparison of microdistributions of taurine and cysteine sulphinate decarboxylase activity with those of GABA and L-glutamate decarboxylase activity in rat spinal cord and thalamus.
Topics: Aminobutyrates; Animals; Carboxy-Lyases; Cysteine; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Male; Organ Specificity; Rats; Spinal Cord; Sulfinic Acids; Taurine; Thalamus | 1978 |
Comparison of transport at the anterior and posterior surfaces of the calf lens.
Topics: Alanine; Amino Acids; Animals; Arginine; Biological Transport; Cattle; Cysteine; Epithelium; gamma-Aminobutyric Acid; Glycine; In Vitro Techniques; Kinetics; Lens, Crystalline; Leucine; Serine | 1977 |
Kinetics of brain glutamate decarboxylase. Inhibition studies with N-(5'-phosphopyridoxyl) amino acids.
Topics: Amino Acids; Aminooxyacetic Acid; Animals; Brain; Carboxy-Lyases; Cysteine; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Glutamates; Kinetics; Mice; Pyridoxal Phosphate | 1977 |
Changes in neurotransmitter parameters in the brain induced by L-cysteine injections in the young rat.
Topics: Acetylcholine; Animals; Brain Chemistry; Choline O-Acetyltransferase; Cysteine; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Glutamates; Glutamic Acid; Injections, Subcutaneous; Neurotransmitter Agents; Rats; Rats, Inbred Strains | 1992 |
Release of endogenous amino acids, including homocysteic acid and cysteine sulphinic acid, from rat hippocampal slices evoked by electrical stimulation of Schaffer collateral-commissural fibres.
Topics: Amino Acids; Animals; Aspartic Acid; Cysteine; Electric Stimulation; Evoked Potentials; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Glycine; Hippocampus; Homocysteine; In Vitro Techniques; Kinetics; Male; Methionine; Nerve Fibers; Neurotransmitter Agents; Pyramidal Tracts; Rats; Rats, Inbred Strains; Time Factors | 1992 |
Excitatory sulphur amino acids evoke a Ca2(+)-independent release of [3H]D-ASP and [3H]GABA from primary neuronal cultures by a mechanism which involves reversal of the high affinity transporters for L-glu and GABA, respectively.
Topics: Animals; Aspartic Acid; Calcium; Carrier Proteins; Cells, Cultured; Cysteine; GABA Plasma Membrane Transport Proteins; gamma-Aminobutyric Acid; Kinetics; Membrane Proteins; Membrane Transport Proteins; Monosaccharide Transport Proteins; Nerve Tissue Proteins; Neurons; Organic Anion Transporters | 1991 |
The interaction between ethanol and cysteine on the central depressant effects of ethanol in mice.
Topics: Animals; Cysteine; Drug Synergism; Ethanol; gamma-Aminobutyric Acid; Injections, Intraventricular; Isethionic Acid; Male; Mice; Posture; Pyrrolidonecarboxylic Acid; Reflex; Thiazoles; Thiazolidines | 1990 |
Cysteine sulfinic acid-induced release of D-[3H]aspartate and [14C]GABA in hippocampus slices: the role of sodium channels and cAMP.
Topics: 1-Methyl-3-isobutylxanthine; Amino Acids; Animals; Aspartic Acid; Calcium; Cnidarian Venoms; Colforsin; Cysteine; gamma-Aminobutyric Acid; Hippocampus; In Vitro Techniques; Male; Neurotoxins; Neurotransmitter Agents; Rats; Sodium Channels; Tetrodotoxin | 1989 |
The effects of putative amino acid neurotransmitters on somata isolated from neurons of the locust central nervous system.
Topics: Action Potentials; Animals; Aspartic Acid; Cysteine; Female; gamma-Aminobutyric Acid; Ganglia; Glutamates; Glutamic Acid; Grasshoppers; Ibotenic Acid; In Vitro Techniques; Kainic Acid; Membrane Potentials; Neurons; Neurotransmitter Agents; Taurine | 1985 |
Neurochemical relation between excitatory and inhibitory amino acids in hippocampus.
Topics: Acetylcholine; Amino Acids; Animals; Aspartic Acid; Cysteine; gamma-Aminobutyric Acid; Hippocampus; In Vitro Techniques; Kainic Acid; Male; N-Methylaspartate; Neurons; Neurotransmitter Agents; Oxadiazoles; Potassium; Quisqualic Acid; Rats; Rats, Inbred Strains | 1985 |
Determination of cysteinesulfinate, hypotaurine and taurine in physiological samples by reversed-phase high-performance liquid chromatography.
Topics: Alanine; Aminobutyrates; Animals; Chromatography, High Pressure Liquid; Cysteine; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Liver; Male; Neurotransmitter Agents; o-Phthalaldehyde; Rats; Rats, Inbred Strains; Spectrometry, Fluorescence; Taurine | 1985 |
Anti-convulsant effects by reduced glutathione and related aminoacids in rats treated with isoniazid.
Topics: Animals; Brain Chemistry; Cysteine; Drug Interactions; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Glutathione; Glycine; Isoniazid; Lethal Dose 50; Male; Rats; Rats, Inbred Strains; Seizures | 1988 |
Inhibition by Diazepam and γ-Aminobutyric Acid of Depolarization-Induced Release of [¹⁴C]Cysteine Sulfinate and [³H]Glutamate in Rat Hippocampal Slices.
Topics: Animals; Carbon Radioisotopes; Cysteine; Diazepam; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Hippocampus; In Vitro Techniques; Kinetics; Male; Neurotransmitter Agents; Rats; Rats, Inbred Strains; Tritium | 1983 |
Neurochemical basis of cysteine sulfinic acid in the central nervous system.
Topics: Animals; Brain; Cysteine; Cysteine Dioxygenase; Dioxygenases; gamma-Aminobutyric Acid; Neurotransmitter Agents; Oxygenases; Potassium; Rats; Sodium; Tissue Distribution | 1983 |
The agonist binding site of the gamma-aminobutyric acid type A channel is not formed by the extracellular cysteine loop.
Topics: Amino Acid Sequence; Animals; Base Sequence; Cloning, Molecular; Cysteine; Diazepam; DNA, Complementary; Electrophoresis, Polyacrylamide Gel; Electrophysiology; gamma-Aminobutyric Acid; Ion Channels; Molecular Sequence Data; Mutagenesis, Site-Directed; Oocytes; Receptors, GABA; Recombinant Proteins; Transcription, Genetic; Xenopus laevis; Zinc | 1994 |
Uptake and receptor sites for glycine in isolated bovine adrenal medulla chromaffin cells.
Topics: Acetamides; Adrenal Medulla; Alanine; Animals; beta-Alanine; Cattle; Cell Membrane; Choline; Cysteine; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Glycine; Kinetics; Ouabain; Receptors, Glycine; Sarcosine; Sodium; Strychnine; Taurine; Temperature | 1993 |
Bicarbonate-sensitive cysteine induced elevation of extracellular aspartate and glutamate in rat hippocampus in vitro.
Topics: Animals; Aspartic Acid; Bicarbonates; Cysteine; Cystine; Extracellular Space; gamma-Aminobutyric Acid; Glutamic Acid; Hippocampus; In Vitro Techniques; Neurotransmitter Agents; Rats; Taurine | 1997 |
Excitatory sulfur-containing amino acid-induced release of [3H]GABA from rat olfactory bulb.
Topics: Animals; Cysteine; Dicarboxylic Acids; Dose-Response Relationship, Drug; Excitatory Amino Acids; gamma-Aminobutyric Acid; Homocysteine; In Vitro Techniques; Male; Neurotransmitter Agents; Neurotransmitter Uptake Inhibitors; Olfactory Bulb; Pyrrolidines; Rats; Rats, Sprague-Dawley; Receptors, Glutamate | 1997 |
Topological localization of cysteine 74 in the GABA transporter, GAT1, and its importance in ion binding and permeation.
Topics: Animals; Biological Transport; Carrier Proteins; Cysteine; Electrophysiology; Extracellular Space; GABA Plasma Membrane Transport Proteins; gamma-Aminobutyric Acid; Membrane Glycoproteins; Membrane Proteins; Membrane Transport Proteins; Mesylates; Mutagenesis, Site-Directed; Organic Anion Transporters; Patch-Clamp Techniques; Structure-Activity Relationship; Sulfhydryl Reagents; Xenopus laevis | 1998 |
Functional significance of the "signature cysteine" in helix 8 of the Escherichia coli 4-aminobutyrate transporter from the amine-polyamine-choline superfamily. Restoration of Cys-300 to the Cys-less Gabp.
Topics: Amino Acid Sequence; Bacterial Proteins; Binding Sites; Biological Transport; Carrier Proteins; Conserved Sequence; Cysteine; Escherichia coli; Escherichia coli Proteins; GABA Plasma Membrane Transport Proteins; gamma-Aminobutyric Acid; Membrane Proteins; Membrane Transport Proteins; Molecular Sequence Data; Mutagenesis, Site-Directed; Organic Anion Transporters; Sequence Alignment | 1998 |
Identification of the amine-polyamine-choline transporter superfamily 'consensus amphipathic region' as the target for inactivation of the Escherichia coli GABA transporter GabP by thiol modification reagents. Role of Cys-300 in restoring thiol sensitivit
Topics: 4-Chloromercuribenzenesulfonate; Amines; Amino Acid Substitution; Biological Transport; Cell Membrane Permeability; Choline; Consensus Sequence; Cysteine; Escherichia coli; Escherichia coli Proteins; Ethylmaleimide; GABA Plasma Membrane Transport Proteins; gamma-Aminobutyric Acid; Kinetics; Membrane Proteins; Membrane Transport Modulators; Membrane Transport Proteins; Mesylates; Models, Biological; Organic Anion Transporters; Polyamines; Protein Conformation; Substrate Specificity; Sulfhydryl Compounds; Sulfhydryl Reagents | 1999 |
Mapping the agonist binding site of the GABAA receptor: evidence for a beta-strand.
Topics: Animals; Binding Sites; Biotin; Chromosome Mapping; Cysteine; Dose-Response Relationship, Drug; Ethyl Methanesulfonate; GABA Agonists; gamma-Aminobutyric Acid; Humans; Indicators and Reagents; Kidney; Membrane Potentials; Models, Molecular; Molecular Sequence Data; Muscimol; Mutagenesis, Site-Directed; Oocytes; Protein Structure, Tertiary; Receptors, GABA-A; Sequence Homology, Amino Acid; Tritium; Xenopus | 1999 |
Gamma-aminobutyric acid increases the water accessibility of M3 membrane-spanning segment residues in gamma-aminobutyric acid type A receptors.
Topics: 4-Chloromercuribenzenesulfonate; Amino Acid Substitution; Animals; Cell Membrane; Cysteine; gamma-Aminobutyric Acid; Hydrophobic and Hydrophilic Interactions; Ion Channel Gating; Mesylates; Mutation; Protein Binding; Protein Conformation; Rats; Receptors, GABA-A; Sulfhydryl Compounds; Surface Properties; Water | 1999 |
Effects of nitric oxide donors on Ca2+-dependent [14C]GABA release from brain synaptosomes: the role of SH-groups.
Topics: Animals; Brain; Calcium; Carbon Isotopes; Cyclic GMP; Cysteine; Dibutyryl Cyclic GMP; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; Ethylmaleimide; gamma-Aminobutyric Acid; Guanylate Cyclase; Hydroxylamine; Kinetics; Male; Methylene Blue; Nitric Oxide Donors; Nitroprusside; Nitroso Compounds; Potassium; Rats; Rats, Wistar; S-Nitrosothiols; src Homology Domains; Sulfhydryl Reagents; Synaptosomes; Time Factors | 2000 |
Structure and dynamics of the GABA binding pocket: A narrowing cleft that constricts during activation.
Topics: Animals; Binding Sites; Biotin; Cells, Cultured; Cysteine; Dose-Response Relationship, Drug; GABA Agonists; GABA Antagonists; GABA Modulators; gamma-Aminobutyric Acid; Ion Channel Gating; Ligands; Mutagenesis, Site-Directed; Oocytes; Patch-Clamp Techniques; Protein Structure, Tertiary; Rats; Receptors, GABA-A; Structure-Activity Relationship; Sulfhydryl Reagents | 2001 |
A (beta)-strand in the (gamma)2 subunit lines the benzodiazepine binding site of the GABA A receptor: structural rearrangements detected during channel gating.
Topics: Allosteric Regulation; Amino Acid Substitution; Animals; Benzodiazepines; Binding Sites; Cells, Cultured; Cysteine; Dose-Response Relationship, Drug; GABA Modulators; gamma-Aminobutyric Acid; Ion Channel Gating; Ligands; Mutagenesis, Site-Directed; Oocytes; Patch-Clamp Techniques; Protein Conformation; Protein Subunits; Rats; Receptors, GABA-A; Structure-Activity Relationship; Sulfhydryl Reagents; Xenopus | 2001 |
Endogenous sulphur-containing amino acids: potent agonists at presynaptic metabotropic glutamate autoreceptors in the rat central nervous system.
Topics: Amino Acids, Sulfur; Animals; Aspartic Acid; Autoreceptors; Calcium; Central Nervous System; Cysteic Acid; Cysteine; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; gamma-Aminobutyric Acid; Glycine; Male; Neurotransmitter Agents; Presynaptic Terminals; Prosencephalon; Pyridines; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate; Resorcinols; Tetrodotoxin; Tritium | 2001 |
GABA(A) receptor beta 2 Tyr97 and Leu99 line the GABA-binding site. Insights into mechanisms of agonist and antagonist actions.
Topics: Amino Acid Sequence; Animals; Binding Sites; Carrier Proteins; Cysteine; Dimerization; DNA, Complementary; Dose-Response Relationship, Drug; GABA Antagonists; gamma-Aminobutyric Acid; Kinetics; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; Oocytes; Patch-Clamp Techniques; Protein Binding; Protein Structure, Secondary; Protein Structure, Tertiary; Pyridazines; Rats; Receptors, GABA-A; Xenopus | 2002 |
GABA(A) receptor M2-M3 loop secondary structure and changes in accessibility during channel gating.
Topics: Amino Acid Sequence; Amino Acid Substitution; Animals; Arginine; Cysteine; gamma-Aminobutyric Acid; Ion Channel Gating; Isoleucine; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Protein Structure, Secondary; Protein Subunits; Quaternary Ammonium Compounds; Rats; Receptors, GABA-A; Recombinant Proteins; Sequence Alignment; Sequence Homology, Amino Acid | 2002 |
Use of the transport specificity ratio and cysteine-scanning mutagenesis to detect multiple substrate specificity determinants in the consensus amphipathic region of the Escherichia coli GABA (gamma-aminobutyric acid) transporter encoded by gabP.
Topics: Amino Acid Sequence; Biological Transport; Carrier Proteins; Consensus Sequence; Cysteine; Escherichia coli Proteins; GABA Plasma Membrane Transport Proteins; gamma-Aminobutyric Acid; Hydrophobic and Hydrophilic Interactions; Isopropyl Thiogalactoside; Kinetics; Membrane Proteins; Membrane Transport Proteins; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Nipecotic Acids; Organic Anion Transporters; Protein Structure, Secondary; Substrate Specificity | 2003 |
The aqueous accessibility in the external half of transmembrane domain I of the GABA transporter GAT-1 Is modulated by its ligands.
Topics: Carrier Proteins; Cysteine; GABA Plasma Membrane Transport Proteins; gamma-Aminobutyric Acid; HeLa Cells; Humans; Ligands; Membrane Proteins; Membrane Transport Proteins; Mutagenesis, Site-Directed; Organic Anion Transporters; Protein Structure, Secondary; Protein Structure, Tertiary; Sodium; Water | 2004 |
Divergence in noncognate amino acid recognition between class I and class II lysyl-tRNA synthetases.
Topics: Amino Acids; Anti-Infective Agents; Bacillus subtilis; Binding Sites; Cell Division; Chromatography, Thin Layer; Cysteine; Escherichia coli; gamma-Aminobutyric Acid; Kinetics; Lysine; Lysine-tRNA Ligase; Models, Molecular; Plasmids; Protein Binding; Substrate Specificity; Time Factors | 2004 |
Evidence that the TM1-TM2 loop contributes to the rho1 GABA receptor pore.
Topics: Amino Acid Sequence; Amino Acid Substitution; Animals; Binding Sites; Cadmium; Cysteine; Ethyl Methanesulfonate; Female; gamma-Aminobutyric Acid; Membrane Potentials; Molecular Sequence Data; Mutagenesis, Site-Directed; Oocytes; Polymerase Chain Reaction; Receptors, GABA; Recombinant Proteins; Transfection; Xenopus laevis | 2004 |
Palmitoylation regulates the clustering and cell surface stability of GABAA receptors.
Topics: Animals; COS Cells; Cysteine; gamma-Aminobutyric Acid; Hippocampus; Neural Inhibition; Neurons; Palmitic Acid; Protein Structure, Tertiary; Protein Subunits; Rats; Receptor Aggregation; Receptors, GABA-A; Synaptic Membranes; Synaptic Transmission | 2004 |
S-methylcysteine may be a causal factor in monohalomethane neurotoxicity.
Topics: Animals; Cells, Cultured; Cysteine; Electric Stimulation; Electrophysiology; gamma-Aminobutyric Acid; Hippocampus; Hydrocarbons, Halogenated; Male; Microscopy, Fluorescence; Neuronal Plasticity; Neurotoxicity Syndromes; Organ Culture Techniques; Patch-Clamp Techniques; Propidium; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Synapses; Synaptic Transmission | 2004 |
Differential protein mobility of the gamma-aminobutyric acid, type A, receptor alpha and beta subunit channel-lining segments.
Topics: Animals; Binding Sites; Cysteine; Diazepam; Disulfides; Dithiothreitol; Dose-Response Relationship, Drug; Electric Conductivity; Ethylmaleimide; gamma-Aminobutyric Acid; Inhibitory Concentration 50; Models, Molecular; Movement; Oocytes; Oxidation-Reduction; Protein Conformation; Protein Subunits; Rats; Receptors, GABA-A; RNA, Messenger; Zinc | 2005 |
Mapping the rho1 GABA(C) receptor agonist binding pocket. Constructing a complete model.
Topics: Amino Acid Sequence; Binding Sites; Cysteine; Dose-Response Relationship, Drug; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Humans; Models, Molecular; Molecular Sequence Data; Mutation; Propylamines; Protein Subunits; Receptors, GABA; Receptors, GABA-A | 2005 |
Transporter-associated currents in the gamma-aminobutyric acid transporter GAT-1 are conditionally impaired by mutations of a conserved glycine residue.
Topics: Animals; Biotinylation; Conserved Sequence; Cysteine; Electric Conductivity; Female; GABA Plasma Membrane Transport Proteins; gamma-Aminobutyric Acid; Gene Expression; Glycine; HeLa Cells; Humans; Lithium; Membrane Transport Proteins; Mesylates; Mutagenesis, Site-Directed; Oocytes; Protein Conformation; RNA, Complementary; Sodium; Structure-Activity Relationship; Sulfhydryl Reagents; Transfection; Tritium; Xenopus laevis | 2005 |
Proximity of transmembrane domains 1 and 3 of the gamma-aminobutyric acid transporter GAT-1 inferred from paired cysteine mutagenesis.
Topics: Biological Transport; Cadmium; Cross-Linking Reagents; Cysteine; GABA Plasma Membrane Transport Proteins; gamma-Aminobutyric Acid; HeLa Cells; Humans; Membrane Transport Proteins; Mutagenesis, Site-Directed; Protein Structure, Tertiary; Sulfhydryl Compounds | 2005 |
A unified view of the role of electrostatic interactions in modulating the gating of Cys loop receptors.
Topics: Acetylcholine; Amino Acid Sequence; Amino Acids; Animals; Biochemistry; Blotting, Western; Bungarotoxins; Cations; Cell Membrane; Cysteine; Cystine; Databases, Protein; Dose-Response Relationship, Drug; Electrodes; Electrophysiology; gamma-Aminobutyric Acid; Glycine; Ions; Kinetics; Ligands; Mice; Models, Chemical; Models, Molecular; Molecular Sequence Data; Mutagenesis; Mutation; Oocytes; Protein Binding; Protein Conformation; Protein Structure, Secondary; Protein Structure, Tertiary; Receptors, Nicotinic; RNA, Messenger; Sequence Homology, Amino Acid; Static Electricity; Torpedo; Xenopus laevis | 2005 |
Role of the conserved glutamine 291 in the rat gamma-aminobutyric acid transporter rGAT-1.
Topics: Amino Acid Sequence; Animals; Conserved Sequence; Cysteine; Electrophysiology; GABA Plasma Membrane Transport Proteins; gamma-Aminobutyric Acid; Gene Expression Regulation; Glutamine; Humans; Lithium; Molecular Sequence Data; Mutation; Patch-Clamp Techniques; Rats; Sequence Alignment | 2006 |
The location of a closed channel gate in the GABAA receptor channel.
Topics: Allosteric Regulation; Animals; Binding, Competitive; Cysteine; Dose-Response Relationship, Drug; GABA Antagonists; gamma-Aminobutyric Acid; Ion Channel Gating; Kinetics; Membrane Potentials; Microinjections; Mutation; Oocytes; Patch-Clamp Techniques; Penicillins; Picrotoxin; Protein Conformation; Rats; Receptors, GABA-A; Xenopus laevis | 2007 |
S-sulfo-cysteine is an endogenous amino acid in neonatal rat brain but an unlikely mediator of cysteine neurotoxicity.
Topics: Amino Acids; Animals; Animals, Newborn; Brain; Cysteine; gamma-Aminobutyric Acid; In Vitro Techniques; Rats; Rats, Sprague-Dawley | 2008 |
Replacement of histidine in position 105 in the α₅ subunit by cysteine stimulates zolpidem sensitivity of α₅β₂γ₂ GABA(A) receptors.
Topics: Amino Acid Substitution; Animals; Cysteine; Dose-Response Relationship, Drug; Electrophysiological Phenomena; Excitatory Amino Acid Agonists; GABA Agonists; gamma-Aminobutyric Acid; Histidine; Humans; Hydrogen-Ion Concentration; Oocytes; Patch-Clamp Techniques; Pyridines; Receptors, GABA-A; Structure-Activity Relationship; Xenopus; Zolpidem | 2007 |
Structural mechanisms underlying benzodiazepine modulation of the GABA(A) receptor.
Topics: Allosteric Regulation; Animals; Benzodiazepines; Binding Sites; Carbolines; Convulsants; Cysteine; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; Indicators and Reagents; Ion Channel Gating; Larva; Membrane Potentials; Mesylates; Microinjections; Mutagenesis, Site-Directed; Oocytes; Patch-Clamp Techniques; Protein Binding; Rats; Receptors, GABA-A; Structure-Activity Relationship; Xenopus | 2008 |
Saturation transfer difference NMR studies on substrates and inhibitors of succinic semialdehyde dehydrogenases.
Topics: Alanine; Aldehydes; Animals; Binding Sites; Cloning, Molecular; Cysteine; Drosophila Proteins; Enzyme Inhibitors; Escherichia coli Proteins; gamma-Aminobutyric Acid; Hydrocarbons, Aromatic; NAD; NADP; Nuclear Magnetic Resonance, Biomolecular; Substrate Specificity; Succinate-Semialdehyde Dehydrogenase | 2008 |
Agonist- and antagonist-induced conformational changes of loop F and their contributions to the rho1 GABA receptor function.
Topics: Amino Acid Sequence; Animals; Cysteine; Female; Fluorescent Dyes; GABA-B Receptor Agonists; GABA-B Receptor Antagonists; gamma-Aminobutyric Acid; Humans; In Vitro Techniques; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Oocytes; Picrotoxin; Protein Conformation; Protein Subunits; Receptors, GABA-B; Recombinant Proteins; Xenopus laevis | 2009 |
Transmembrane domain 8 of the {gamma}-aminobutyric acid transporter GAT-1 lines a cytoplasmic accessibility pathway into its binding pocket.
Topics: Aspartic Acid; Cysteine; Cytoplasm; GABA Plasma Membrane Transport Proteins; gamma-Aminobutyric Acid; HeLa Cells; Humans; Models, Biological; Mutation; Protein Binding; Protein Structure, Secondary; Protein Structure, Tertiary; Protein Transport; Serine | 2009 |
Relative positioning of diazepam in the benzodiazepine-binding-pocket of GABA receptors.
Topics: Allosteric Regulation; Animals; Anti-Anxiety Agents; Benzodiazepines; Binding Sites; Biophysics; Cell Line, Transformed; Cysteine; Diazepam; Dizocilpine Maleate; Dose-Response Relationship, Drug; Electric Stimulation; Flumazenil; GABA Modulators; gamma-Aminobutyric Acid; Humans; Membrane Potentials; Oocytes; Point Mutation; Protein Binding; Receptors, GABA-A; Structure-Activity Relationship; Transfection; Xenopus | 2009 |
Brain perfusion in fibromyalgia patients and its differences between responders and poor responders to gabapentin.
Topics: Adult; Aged; Amines; Analgesics; Brain; Cerebrovascular Circulation; Cyclohexanecarboxylic Acids; Cysteine; Female; Fibromyalgia; Gabapentin; gamma-Aminobutyric Acid; Humans; Middle Aged; Organotechnetium Compounds; Radiopharmaceuticals; Tomography, Emission-Computed, Single-Photon; Treatment Failure; Young Adult | 2010 |
A transmembrane amino acid in the GABAA receptor β2 subunit critical for the actions of alcohols and anesthetics.
Topics: 1-Butanol; 1-Octanol; Alcohols; Amino Acid Substitution; Anesthetics; Animals; Asparagine; Binding Sites; Cysteine; Dose-Response Relationship, Drug; Drug Synergism; Ethanol; Female; gamma-Aminobutyric Acid; Humans; Ion Channel Gating; Isoflurane; Oocytes; Patch-Clamp Techniques; Rats; Receptors, GABA-A; RNA, Complementary; Thiosulfonic Acids; Xenopus laevis | 2010 |
Two amino acid residues contribute to a cation-π binding interaction in the binding site of an insect GABA receptor.
Topics: Animals; Binding Sites; Cysteine; Female; gamma-Aminobutyric Acid; Hydrogen Bonding; Insect Proteins; Mutagenesis, Site-Directed; Oocytes; Phenylalanine; Protein Structure, Tertiary; Protein Subunits; Spodoptera; Tyrosine; Xenopus laevis | 2011 |
The TM2 6' position of GABA(A) receptors mediates alcohol inhibition.
Topics: Alcohols; Amino Acid Substitution; Animals; Binding Sites; Binding, Competitive; Cysteine; Cystine; DNA, Complementary; Drug Synergism; Electrophysiological Phenomena; Ethanol; Etomidate; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Humans; Methionine; Methyl Methanesulfonate; Molecular Dynamics Simulation; Oocytes; Patch-Clamp Techniques; Receptors, GABA-A; Tryptophan; Xenopus laevis | 2012 |
Increased neuronal glutathione and neuroprotection in GTRAP3-18-deficient mice.
Topics: Analysis of Variance; Animals; Brain; Calcium-Binding Proteins; Carrier Proteins; Cysteine; Excitatory Amino Acid Transporter 3; Exploratory Behavior; gamma-Aminobutyric Acid; Glial Fibrillary Acidic Protein; Glutamic Acid; Glutathione; Glycine; Heat-Shock Proteins; Hippocampus; In Vitro Techniques; Maze Learning; Membrane Transport Proteins; Mice; Mice, Inbred C57BL; Mice, Knockout; Microfilament Proteins; Molsidomine; Motor Activity; Neurons; Nitric Oxide Donors; Phenotype; Phosphopyruvate Hydratase; Time Factors | 2012 |
Functional consequences of sulfhydryl modification of the γ-aminobutyric acid transporter 1 at a single solvent-exposed cysteine residue.
Topics: Animals; Cysteine; Dithiothreitol; Ethylmaleimide; Female; GABA Plasma Membrane Transport Proteins; gamma-Aminobutyric Acid; Gene Expression; Humans; Kinetics; Mesylates; Mutation; Oocytes; Patch-Clamp Techniques; Rhodamines; Sodium Chloride; Sulfhydryl Reagents; Transfection; Valproic Acid; Xenopus laevis | 2012 |
GABA(A) receptor transmembrane amino acids are critical for alcohol action: disulfide cross-linking and alkyl methanethiosulfonate labeling reveal relative location of binding sites.
Topics: Amino Acids; Animals; Binding Sites; Central Nervous System Depressants; Cloning, Molecular; Cross-Linking Reagents; Cysteine; Disulfides; Dose-Response Relationship, Drug; Electrophysiological Phenomena; Ethanol; GABA Agents; gamma-Aminobutyric Acid; Humans; Mesylates; Models, Molecular; Oocytes; Oxidation-Reduction; Receptors, GABA-A; Xenopus laevis | 2014 |
Neuronal nitric oxide synthase-dependent S-nitrosylation of gephyrin regulates gephyrin clustering at GABAergic synapses.
Topics: Animals; Carrier Proteins; Cell Line, Transformed; Cysteine; gamma-Aminobutyric Acid; Green Fluorescent Proteins; Hippocampus; Humans; Membrane Proteins; Mice; Nitric Oxide Synthase Type I; Presynaptic Terminals; Receptors, GABA-A; S-Nitrosothiols; Synapses; Transfection; Vesicular Inhibitory Amino Acid Transport Proteins | 2014 |
Palmitoylation of gephyrin controls receptor clustering and plasticity of GABAergic synapses.
Topics: Acyltransferases; Animals; Carrier Proteins; Cysteine; gamma-Aminobutyric Acid; Hippocampus; Humans; Lipoylation; Membrane Proteins; Mice; Neuronal Plasticity; Receptors, GABA-A; Synapses | 2014 |
Conformationally sensitive proximity of extracellular loops 2 and 4 of the γ-aminobutyric acid (GABA) transporter GAT-1 inferred from paired cysteine mutagenesis.
Topics: Animals; Choline; Cysteine; Escherichia coli; Female; GABA Plasma Membrane Transport Proteins; gamma-Aminobutyric Acid; Gene Expression; Gluconates; HeLa Cells; Humans; Membrane Potentials; Models, Molecular; Mutation; Oocytes; Patch-Clamp Techniques; Phenanthrolines; Protein Interaction Domains and Motifs; Protein Structure, Secondary; Recombinant Proteins; Xenopus laevis | 2014 |
GABAA receptor cysteinyl mutants and the ginkgo terpenoid lactones bilobalide and ginkgolides.
Topics: Animals; Base Sequence; Bilobalides; Binding Sites; Cysteine; Dose-Response Relationship, Drug; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Ginkgo biloba; Ginkgolides; Humans; Mutation; Protein Binding; Receptors, GABA-A; Sulfhydryl Compounds | 2016 |
Negative modulation of the GABA
Topics: Animals; Binding, Competitive; Chlorides; Cysteine; Cystine; Dose-Response Relationship, Drug; Ethylmaleimide; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Homocysteine; Humans; Ion Transport; Oocytes; Patch-Clamp Techniques; Receptors, GABA-A; Recombinant Proteins; RNA, Complementary; Xenopus laevis | 2018 |
Selective determination of the catalytic cysteine pK
Topics: Acinetobacter baumannii; Amino Acid Sequence; Amino Acid Substitution; Bacterial Proteins; Biocatalysis; Catalytic Domain; Crystallography, X-Ray; Cysteine; gamma-Aminobutyric Acid; Hydrogen-Ion Concentration; Kinetics; NADP; Sequence Homology, Amino Acid; Substrate Specificity; Succinate-Semialdehyde Dehydrogenase | 2018 |
Role of cysteine in the improvement of γ-aminobutyric acid production by nonproteolytic Levilactobacillus brevis in coculture with Streptococcus thermophilus.
Topics: Animals; Caseins; Coculture Techniques; Cysteine; Fermentation; gamma-Aminobutyric Acid; Lactobacillus delbrueckii; Peptides; Sodium Glutamate; Streptococcus thermophilus; Yogurt | 2022 |
Activation of the Rat α1β2ε GABA
Topics: Animals; Cysteine; gamma-Aminobutyric Acid; Pentobarbital; Propofol; Rats; Receptors, GABA-A | 2022 |
Cysteine protected cells from H
Topics: Cysteine; Fatty Acids; Fermentation; gamma-Aminobutyric Acid; Hydrogen Peroxide; Levilactobacillus brevis; Sodium Glutamate | 2022 |
Rapid, sensitive analysis method for determining the nitrogen stable isotope ratio of total free amino acids in soil.
Topics: Alanine; Amino Acids; Arginine; Asparagine; Aspartic Acid; Cysteine; gamma-Aminobutyric Acid; Glutamic Acid; Glycine; Histidine; Leucine; Lysine; Nitrogen; Nitrogen Isotopes; Phenylalanine; Serine; Soil; Tryptophan | 2022 |
Interactions between dopamine transporter and N-methyl-d-aspartate receptor-related amino acids on cognitive impairments in schizophrenia.
Topics: Amino Acids; Arginine; Aspartic Acid; Cognitive Dysfunction; Corpus Striatum; Cysteine; Dopamine; Dopamine Plasma Membrane Transport Proteins; gamma-Aminobutyric Acid; Glutamates; Humans; Methionine; Receptors, N-Methyl-D-Aspartate; Schizophrenia; Tomography, Emission-Computed, Single-Photon; Tropanes | 2022 |
Differential sensitivity of metabolic pathways in sugar beet roots to combined salt, heat, and light stress.
Topics: Aspartic Acid; Beta vulgaris; Chlorides; Citric Acid; Cysteine; gamma-Aminobutyric Acid; Gene Expression Regulation, Plant; Glucose; Hot Temperature; Mannitol; Metabolic Networks and Pathways; Plant Roots; Proline; Salinity; Salts; Sodium Chloride; Stress, Physiological; Sugars; Tryptophan; Tyrosine | 2022 |
Tong-Xie-Yao-Fang alleviates diarrhea-predominant irritable bowel syndrome in rats via the GCN2/PERK-eIF2α-ATF4 signaling pathway.
Topics: Activating Transcription Factor 4; Animals; Body Weight; Caspase 3; Cysteine; Diarrhea; Drugs, Chinese Herbal; eIF-2 Kinase; Eukaryotic Initiation Factor-2; gamma-Aminobutyric Acid; Glycine; Irritable Bowel Syndrome; Lysine; Maternal Deprivation; Proto-Oncogene Proteins c-bcl-2; Rats; Signal Transduction; Trinitrobenzenesulfonic Acid; Water | 2022 |
Microwave-assisted synthesis of blue fluorescent molybdenum nanoclusters with maltose-cysteine Schiff base for detection of myoglobin and γ-aminobutyric acid in biofluids.
Topics: Cysteine; Fluorescent Dyes; gamma-Aminobutyric Acid; Maltose; Microwaves; Molybdenum; Myoglobin; Schiff Bases; Spectrometry, Fluorescence; Spectroscopy, Fourier Transform Infrared | 2023 |
Effects of L-Cysteine and γ-Aminobutyric Acid Treatment on Postharvest Quality and Antioxidant Activity of Loquat Fruit during Storage.
Topics: Antioxidants; Cysteine; Eriobotrya; Fruit; gamma-Aminobutyric Acid | 2023 |
Analysis of ATG4C function
Topics: Animals; Autophagy; Autophagy-Related Proteins; Cysteine; gamma-Aminobutyric Acid; Mammals; Mice; Microtubule-Associated Proteins | 2023 |
Three-dimensional quantitative structure-activity relationship analyses of substrates of the human proton-coupled amino acid transporter 1 (hPAT1).
Topics: Amino Acid Transport Systems; Caco-2 Cells; Endocytosis; Humans; Kinetics; Models, Chemical; Models, Molecular; Molecular Conformation; Quantitative Structure-Activity Relationship; Substrate Specificity; Symporters | 2011 |