Compounds > cysteine

cysteine and fumarates

cysteine has been researched along with fumarates in 38 studies

Research

Studies (38)

TimeframeStudies, this research(%)All Research%
pre-199013 (34.21)18.7374
1990's1 (2.63)18.2507
2000's7 (18.42)29.6817
2010's9 (23.68)24.3611
2020's8 (21.05)2.80

Authors

AuthorsStudies
Kallistratos, G1
Rao, MR; Subramanian, SS1
Ellison, JS; Siegel, L1
Cain, RB; Houghton, C; Wright, KA1
Hill, RL; Steinman, HM1
Azoulay, E; Puig, J2
Basappa, SC; Rehácek, Z1
Williams, VR; Wu, WT1
Degroot, LJ1
Beranová, S; Giorgianni, F; Viola, RE; Wesdemiotis, C1
Björnberg, O; Jensen, KF; Jordan, DB; Palfey, BA1
BARKER, HA; IODICE, A; ROOZE, V; SUZUKI, F1
SELBIN, J; WILLIAMS, VR1
VAUGHN, RH; YORK, GK1
Bochenek, M; Ryszka, F; Smorag, Z; Szcześniak-Fabiańczyk, B1
Alderson, NL; Alt, N; Baynes, JW; Blatnik, M; Carson, JA; Frizzell, N; Lyons, TJ; Nagai, R; Thorpe, SR; Walla, MD; Wang, Y1
Baatz, JE; Baynes, JW; Bethard, J; Blatnik, M; Brock, JW; Frizzell, N; Nagai, R; Thorpe, SR; Walla, MD1
Baynes, JW; Blatnik, M; Frizzell, N; Thorpe, SR1
Belmont, M; Lien, CA; Savard, P; Savarese, JJ; Sunaga, H1
Dolińska, B; Ostrózka-Cieślik, A; Ryszka, F1
Adam, J; Berquand, A; Fischer, R; Frizzell, N; Igarashi, K; Kato, K; Kessler, BM; Kitagawa, M; Lappin, T; Laroyia, M; O'Flaherty, L; Pollard, PJ; Saito, K; Soga, T; Ternette, N; Wolhulter, K; Yang, M1
Frizzell, N; Manuel, AM1
Brennan, MS; Gao, B; Hronowski, X; Juhasz, P; Li, B; Matos, MF; Rhodes, KJ; Scannevin, RH1
Baatz, JE; Clapper, AC; Frizzell, N; Manuel, AM; Palmiter, RD; Piroli, GG; Quintana, A; Walla, MD1
Beccuti, M; Cordero, F; Giraudo, MT; Miglio, G; Sabatino, AD; Veglia, E1
Ehrt, S; Frizzell, N; Jansen, R; Jayachandran, P; Molina, H; Piroli, GG; Puckett, S; Rhee, KY; Ruecker, N; Trujillo, C1
Miglio, G1
Cooper, AJL; Fiehn, O; Folz, J; Hanson, AD; McCarty, DR; Moraga Amador, D; Niehaus, TD1
Alpsoy, A; Bak, DW; Bavari, AE; Bergholtz, SE; Briney, CA; Crooks, DR; Dykhuizen, EC; Florens, L; Frizzell, N; Kulkarni, RA; Levy, M; Linehan, WM; Meier, JL; Shrimp, JH; Thorpe, AL; Washburn, MP; Weerapana, E; Wei, D1
Bergholtz, SE; Briney, CA; Linehan, WM; Meier, JL; Najera, SS; Perez, M1
Arimilli, BS; Bak, DW; Bergholtz, SE; Crooks, DR; Linehan, WM; Meier, JL; Perez, M; Weerapana, E; Yang, Y1
Ellis, HR; Kammerer, B; Lagies, S; Matthews, A; Schleicher, E; Schönfelder, J; Stull, F; Teufel, R1
Katsuta, N; Nagai, M; Nagai, R; Sugawa, H; Takahashi, H1
Chen, H; Fu, Y; Ge, X; Guo, H; Hu, Z; Li, M; Li, X; Meng, L; Qian, X; Shi, Z; Yin, J; Zhao, N; Zhao, X1
Chen, LC; Garda, VG; Hofmann, KL; Montaño, JL; Volk, RF; Wang, BJ; Warrington, SE; Zaro, BW1
Bak, DW; Conte, AN; Linehan, WM; Meier, JL; Najera, SS; Nance, KD; Perez, M; Thalalla Gamage, S; Weerapana, E1
Erickson, NA; Goethel, ME; Hillmann, KB; Niehaus, TD1

Reviews

2 review(s) available for cysteine and fumarates

ArticleYear
GLUTAMATE MUTASE REACTION.
    Annals of the New York Academy of Sciences, 1964, Apr-24, Volume: 112

    Topics: Amino Acids; Clostridium; Cysteine; Dimercaprol; Fumarates; Glutamates; Glycine; Intramolecular Transferases; Isomerases; Ketoglutaric Acids; Mercaptoethanol; Metabolism; Pharmacology; Propionates; Research; Spectrophotometry; Sulfhydryl Compounds

1964
Fumarates: unique nondepolarizing neuromuscular blocking agents that are antagonized by cysteine.
    Journal of critical care, 2009, Volume: 24, Issue:1

    Topics: Anesthesia Recovery Period; Animals; Atracurium; Cats; Chemistry, Pharmaceutical; Cholinesterase Inhibitors; Cysteine; Dogs; Drug Evaluation, Preclinical; Fumarates; Haplorhini; Hemodynamics; Humans; Isoquinolines; Metabolic Clearance Rate; Neuromuscular Nondepolarizing Agents; Safety; Stereoisomerism; Time Factors

2009

Other Studies

36 other study(ies) available for cysteine and fumarates

ArticleYear
[Prevention of 3,4-benzpyrene carcinogenesis by naturally occurring and synthetic compounds].
    MMW, Munchener medizinische Wochenschrift, 1975, Mar-07, Volume: 117, Issue:10

    Topics: Aconitic Acid; Animals; Antineoplastic Agents; Benzopyrenes; Cadaverine; Carcinogens; Cysteine; Dicarboxylic Acids; Dithiothreitol; Ethanolamines; Female; Fumarates; Maleates; Mice; Neoplasms, Experimental; Putrescine; Spermidine; Spermine; Sulfhydryl Compounds; Tricarboxylic Acids

1975
Purification and properties of citraconase.
    The Journal of biological chemistry, 1968, May-10, Volume: 243, Issue:9

    Topics: Air; Ascorbic Acid; Bacteria; Benzoates; Copper; Cysteine; Diphosphates; Edetic Acid; Enzyme Induction; Fumarates; Glutathione; Hydro-Lyases; Hydrogen-Ion Concentration; Iodoacetates; Iron; Isocitrate Dehydrogenase; Kinetics; Malates; Maleates; Mercaptoethanol; Mercury; Phenanthrolines; Pyridines; Quinolines; Thioglycolates; Time Factors

1968
Role of tyrosine in the substrate binding site of mitochondrial L-malate dehydrogenase from bovine heart muscle.
    Biochemistry, 1971, Jul-20, Volume: 10, Issue:15

    Topics: Acetates; Acylation; Animals; Aspartic Acid; Binding Sites; Carbon Isotopes; Carboxylic Acids; Catalysis; Cattle; Chemical Phenomena; Chemistry; Chlorides; Cysteine; Dicarboxylic Acids; Enzyme Activation; Fumarates; Glutamates; Hydrogen-Ion Concentration; Hydroxylamines; Imidazoles; Kinetics; Malate Dehydrogenase; Malates; Mercuribenzoates; Methane; Mitochondria, Muscle; Myocardium; NAD; Spectrophotometry; Sulfates; Sulfonic Acids; Tyrosine

1971
Microbial metabolism of the pyridine ring. Metabolism of 2- and 3-hydroxypyridines by the maleamate pathway in Achromobacter sp.
    The Biochemical journal, 1974, Volume: 140, Issue:2

    Topics: Alcaligenes; Amides; Ammonia; Ammonium Sulfate; Centrifugation; Chelating Agents; Chromatography, Paper; Cysteine; Dithiothreitol; Fumarates; Glutathione; Iron; Maleates; Oxygenases; Pyridines

1974
Bovine liver crotonase. Substrate analogs and chemical modification of cysteinyl residues.
    The Journal of biological chemistry, 1973, Feb-10, Volume: 248, Issue:3

    Topics: Acetamides; Animals; Binding Sites; Binding, Competitive; Bromine; Catalysis; Cattle; Chlorine; Cinnamates; Coenzyme A; Crotonates; Cyclohexanecarboxylic Acids; Cysteine; Disulfides; Fumarates; Hydro-Lyases; Kinetics; Liver; Spectrophotometry; Structure-Activity Relationship; Sulfhydryl Compounds; Sulfhydryl Reagents; Sulfides

1973
[Regulation of the synthesis of nitrate reductase in Escherichia coli K12].
    Annales de l'Institut Pasteur, 1969, Volume: 117, Issue:4

    Topics: Cysteine; Enzyme Induction; Escherichia coli; Fumarates; Genetic Complementation Test; Molecular Biology; Mutation; Nitrates; Oxidoreductases; Oxygen

1969
[Regulation of the synthesis of nitrate reductase in Escherichia coli K12].
    Annales de l'Institut Pasteur, 1969, Volume: 117, Issue:4

    Topics: Cysteine; Enzyme Induction; Escherichia coli; Fumarates; Genetic Complementation Test; Molecular Biology; Mutation; Nitrates; Oxidoreductases; Oxygen

1969
Effect of Tween 80 on alkaloid-producing cultures of Claviceps paspali.
    Folia microbiologica, 1971, Volume: 16, Issue:2

    Topics: Acids; Alanine; Amino Acids; Ascomycota; Chromatography, Paper; Citrates; Colorimetry; Culture Media; Cysteine; Ergot Alkaloids; Fumarates; Histidine; Methionine; Oxaloacetates; Spectrophotometry; Succinates; Surface-Active Agents

1971
Subunit structure and isolation of a peptide containing the reactive cysteine group of beta-methylaspartase.
    The Journal of biological chemistry, 1968, Nov-10, Volume: 243, Issue:21

    Topics: Amino Acids; Aspartic Acid; Binding Sites; Carbon Isotopes; Chromatography; Chromatography, Gel; Chromatography, Ion Exchange; Cysteine; Electrophoresis; Ethylmaleimide; Fumarates; Lyases; Peptides; Protein Hydrolysates; Sulfhydryl Compounds; Trypsin

1968
Stimulation and inhibition of thyroid iodinating enzyme systems.
    Biochimica et biophysica acta, 1967, Mar-22, Volume: 136, Issue:2

    Topics: Aminopterin; Animals; Cattle; Cysteine; Folic Acid; Fumarates; Hydrogen Peroxide; Hydrogen-Ion Concentration; In Vitro Techniques; Iodine; Iodine Isotopes; Microsomes; Mitochondria; Penicillamine; Peroxidases; Phenanthrolines; Thyroid Gland

1967
Mapping the mechanism-based modification sites in L-aspartase from Escherichia coli.
    Archives of biochemistry and biophysics, 1997, May-15, Volume: 341, Issue:2

    Topics: Aspartate Ammonia-Lyase; Aspartic Acid; Bacterial Proteins; Chromatography, High Pressure Liquid; Cysteine; Deamination; Enzyme Inhibitors; Escherichia coli; Fumarates; Lysine; Mutagenesis, Site-Directed; Peptide Fragments

1997
Dihydrooxonate is a substrate of dihydroorotate dehydrogenase (DHOD) providing evidence for involvement of cysteine and serine residues in base catalysis.
    Archives of biochemistry and biophysics, 2001, Jul-15, Volume: 391, Issue:2

    Topics: Binding Sites; Catalysis; Cysteine; Dihydroorotate Dehydrogenase; Escherichia coli; Fumarates; Lactobacillus; Mutation; Orotic Acid; Oxidoreductases; Oxidoreductases Acting on CH-CH Group Donors; Recombinant Proteins; Serine; Substrate Specificity

2001
DIVALENT METAL ION ACTIVATION OF BETA-METHYLASPARTASE.
    The Journal of biological chemistry, 1964, Volume: 239

    Topics: Ammonia; Ammonia-Lyases; Aspartic Acid; Benzoates; Cadmium; Calcium; Cations, Divalent; Chemical Phenomena; Chemistry, Physical; Clostridium; Cobalt; Copper; Cysteine; Fumarates; Ions; Iron; Lyases; Magnesium; Manganese; Nickel; Pharmacology; Research; Spectrophotometry; Zinc

1964
MECHANISMS IN THE INHIBITION OF MICROORGANISMS BY SORBIC ACID.
    Journal of bacteriology, 1964, Volume: 88

    Topics: Acetates; Carbohydrate Metabolism; Cysteine; Escherichia coli; Fatty Acids; Fumarate Hydratase; Fumarates; Glucose; Malates; Metabolism; Oxidation-Reduction; Pharmacology; Pseudomonas aeruginosa; Pyruvates; Research; Sorbic Acid; Succinates; Succinic Acid

1964
Effect of antioxidants added to boar semen extender on the semen survival time and sperm chromatin structure.
    Reproductive biology, 2003, Volume: 3, Issue:1

    Topics: Adenosine; Animals; Antioxidants; Ascorbic Acid; Chromatin; Cysteine; Fumarates; Male; Prolactin; Semen Preservation; Sperm Motility; Spermatozoa; Sus scrofa

2003
S-(2-Succinyl)cysteine: a novel chemical modification of tissue proteins by a Krebs cycle intermediate.
    Archives of biochemistry and biophysics, 2006, Jun-01, Volume: 450, Issue:1

    Topics: Animals; Anticarcinogenic Agents; Citric Acid Cycle; Collagen; Cysteine; Diabetes Mellitus, Experimental; Female; Fumarates; Glycation End Products, Advanced; Glyceraldehyde-3-Phosphate Dehydrogenases; Humans; Insulin; Insulin, Long-Acting; Insulin, Regular, Human; Muscle Proteins; Protein Processing, Post-Translational; Radiation-Protective Agents; Rats; Rats, Sprague-Dawley; Serum Albumin; Serum Albumin, Human; Skin; Succinic Acid

2006
Succination of protein thiols during adipocyte maturation: a biomarker of mitochondrial stress.
    The Journal of biological chemistry, 2007, Nov-23, Volume: 282, Issue:47

    Topics: 3T3 Cells; Adipocytes; Adipogenesis; Adipose Tissue; Animals; Biomarkers; Cell Differentiation; Citric Acid Cycle; Cysteine; Diabetes Complications; Diabetes Mellitus, Type 2; Fibroblasts; Fumarates; Humans; Insulin Resistance; Lysine; Mice; Mitochondria; Obesity; Protein Processing, Post-Translational; Risk Factors; Stress, Physiological; Succinic Acid; Sulfhydryl Compounds

2007
Inactivation of glyceraldehyde-3-phosphate dehydrogenase by fumarate in diabetes: formation of S-(2-succinyl)cysteine, a novel chemical modification of protein and possible biomarker of mitochondrial stress.
    Diabetes, 2008, Volume: 57, Issue:1

    Topics: Animals; Chromatography, Liquid; Cysteine; Diabetes Mellitus, Experimental; Fumarates; Gas Chromatography-Mass Spectrometry; Glyceraldehyde 3-Phosphate Dehydrogenase (NADP+); Kinetics; Mass Spectrometry; Mitochondria; Muscle, Skeletal; Peptide Fragments; Rats

2008
Influence of the selected antioxidants on the stability of the Celsior solution used for perfusion and organ preservation purposes.
    AAPS PharmSciTech, 2009, Volume: 10, Issue:2

    Topics: Antioxidants; Ascorbic Acid; Cysteine; Disaccharides; Drug Stability; Electrolytes; Fumarates; Glutamates; Glutathione; Histidine; Mannitol; Organ Preservation Solutions; Perfusion; Temperature

2009
Inhibition of mitochondrial aconitase by succination in fumarate hydratase deficiency.
    Cell reports, 2013, Mar-28, Volume: 3, Issue:3

    Topics: Aconitate Hydratase; Animals; Cell Line; Cysteine; Fumarate Hydratase; Fumarates; Humans; Iron; Kidney Neoplasms; Leiomyomatosis; Mice; Mice, Transgenic; Mitochondria; Neoplastic Syndromes, Hereditary; Proteome; Skin Neoplasms; Succinic Acid; Uterine Neoplasms

2013
Adipocyte protein modification by Krebs cycle intermediates and fumarate ester-derived succination.
    Amino acids, 2013, Volume: 45, Issue:5

    Topics: 3T3 Cells; Adipocytes; Animals; Citric Acid Cycle; Cysteine; Fumarates; Glucose; Mice; Protein Processing, Post-Translational; Proteins

2013
Dimethyl fumarate and monoethyl fumarate exhibit differential effects on KEAP1, NRF2 activation, and glutathione depletion in vitro.
    PloS one, 2015, Volume: 10, Issue:3

    Topics: Astrocytes; Cell Nucleus; Cysteine; Dimethyl Fumarate; Extracellular Space; Fumarates; Gene Expression Regulation; Glutathione; HEK293 Cells; Humans; Intracellular Signaling Peptides and Proteins; Kelch-Like ECH-Associated Protein 1; NF-E2-Related Factor 2; Protein Transport

2015
Succination is Increased on Select Proteins in the Brainstem of the NADH dehydrogenase (ubiquinone) Fe-S protein 4 (Ndufs4) Knockout Mouse, a Model of Leigh Syndrome.
    Molecular & cellular proteomics : MCP, 2016, Volume: 15, Issue:2

    Topics: Animals; Brain Stem; Citric Acid Cycle; Cysteine; Disease Models, Animal; Electron Transport Complex I; Fumarates; Humans; Leigh Disease; Mice; Mice, Knockout; Mitochondria; Protein Processing, Post-Translational; Proteomics; Succinates; Tandem Mass Spectrometry

2016
A computational analysis of S-(2-succino)cysteine sites in proteins.
    Biochimica et biophysica acta, 2016, Volume: 1864, Issue:2

    Topics: Amino Acids; Computational Biology; Cysteine; Fumarates; Humans; Models, Theoretical; Molecular Conformation; Protein Processing, Post-Translational; Proteins; Proteome; Sequence Analysis, Protein; Succinates

2016
Fumarase Deficiency Causes Protein and Metabolite Succination and Intoxicates Mycobacterium tuberculosis.
    Cell chemical biology, 2017, Mar-16, Volume: 24, Issue:3

    Topics: Animals; Bacterial Proteins; Chromatography, High Pressure Liquid; Citric Acid Cycle; Cysteine; Female; Fumarate Hydratase; Fumarates; Mice; Mice, Inbred C57BL; Mycobacterium tuberculosis; Oxidative Stress; Peptides; Protein Processing, Post-Translational; Tandem Mass Spectrometry

2017
Analysis of fumarate-sensitive proteins and sites by exploiting residue interaction networks.
    Amino acids, 2018, Volume: 50, Issue:5

    Topics: Cysteine; Databases, Protein; Fumarates; Proteins; Sequence Analysis, Protein

2018
Identification of a metabolic disposal route for the oncometabolite
    The Journal of biological chemistry, 2018, 05-25, Volume: 293, Issue:21

    Topics: Acetylation; Bacillus subtilis; Cysteine; Fumarates; Metabolomics; Neoplasms; Operon; Signal Transduction

2018
A chemoproteomic portrait of the oncometabolite fumarate.
    Nature chemical biology, 2019, Volume: 15, Issue:4

    Topics: Cell Line, Tumor; Chromatography, Liquid; Cysteine; Fumarates; HEK293 Cells; Humans; Hydrogen-Ion Concentration; Leiomyomatosis; Models, Biological; Neoplastic Syndromes, Hereditary; Proteomics; Signal Transduction; Skin Neoplasms; Tandem Mass Spectrometry; Uterine Neoplasms

2019
An Oncometabolite Isomer Rapidly Induces a Pathophysiological Protein Modification.
    ACS chemical biology, 2020, 04-17, Volume: 15, Issue:4

    Topics: Acylation; Cell Line, Tumor; Cysteine; Fumarates; HEK293 Cells; Humans; Hydrogen-Ion Concentration; Maleates; Phenols; Protein Processing, Post-Translational; Proteome; Proteomics; Succinates; Sulfhydryl Compounds

2020
Heterogeneous adaptation of cysteine reactivity to a covalent oncometabolite.
    The Journal of biological chemistry, 2020, 09-25, Volume: 295, Issue:39

    Topics: Cell Line, Tumor; Cysteine; Fumarate Hydratase; Fumarates; Humans; Kidney Neoplasms; Leiomyomatosis; Neoplastic Syndromes, Hereditary; Skin Neoplasms; Uterine Neoplasms

2020
Bacterial flavoprotein monooxygenase YxeK salvages toxic S-(2-succino)-adducts via oxygenolytic C-S bond cleavage.
    The FEBS journal, 2022, Volume: 289, Issue:3

    Topics: Acetylation; Bacillus subtilis; Cysteine; Flavins; Flavoproteins; Fumarates; Kinetics; Mixed Function Oxygenases; Models, Chemical; Mutagenesis, Site-Directed; Operon; Substrate Specificity; Sulfhydryl Compounds

2022
Changes in S-(2-succinyl)cysteine and advanced glycation end-products levels in mouse tissues associated with aging.
    Amino acids, 2022, Volume: 54, Issue:4

    Topics: Aging; Animals; Chromatography, Liquid; Cysteine; Fumarates; Glycation End Products, Advanced; Male; Mice; Mice, Inbred C57BL; Tandem Mass Spectrometry

2022
Fumarate inhibits PTEN to promote tumorigenesis and therapeutic resistance of type2 papillary renal cell carcinoma.
    Molecular cell, 2022, 04-07, Volume: 82, Issue:7

    Topics: Carcinogenesis; Carcinoma, Papillary; Carcinoma, Renal Cell; Cysteine; Drug Resistance, Neoplasm; Fumarate Hydratase; Fumarates; Humans; Kidney Neoplasms; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; PTEN Phosphohydrolase; Sunitinib

2022
Improved Electrophile Design for Exquisite Covalent Molecule Selectivity.
    ACS chemical biology, 2022, 06-17, Volume: 17, Issue:6

    Topics: Agammaglobulinaemia Tyrosine Kinase; Cysteine; Fumarates; Protein Kinase Inhibitors; Proteomics

2022
Conditional Covalent Lethality Driven by Oncometabolite Accumulation.
    ACS chemical biology, 2022, 10-21, Volume: 17, Issue:10

    Topics: Cysteine; Fumarate Hydratase; Fumarates; Humans; Ligands; Neoplastic Syndromes, Hereditary; RNA, Transfer; tRNA Methyltransferases

2022
Identification of a S-(2-succino)cysteine breakdown pathway that uses a novel S-(2-succino) lyase.
    The Journal of biological chemistry, 2022, Volume: 298, Issue:12

    Topics: Acetylcysteine; Cysteine; Fumarates; Lyases; Sulfhydryl Compounds

2022