cysteine and fluorouracil

cysteine has been researched along with fluorouracil in 21 studies

Research

Studies (21)

TimeframeStudies, this research(%)All Research%
pre-199011 (52.38)18.7374
1990's2 (9.52)18.2507
2000's1 (4.76)29.6817
2010's3 (14.29)24.3611
2020's4 (19.05)2.80

Authors

AuthorsStudies
Kawabata, N; Nakashima, T; Ohno, H; Yano, K1
Araki, E; Hoshi, A; Iigo, M; Nakajima, Y1
Hoshi, A; Iigo, M; Kitagawa, H1
De Clercq, E; Hoshi, A; Iigo, M; Nakajima, Y1
Hoshi, A; Iigo, M1
Oshima, T; Tsukiyama, I1
Franke, HD1
Schmerold, I; Tempel, K; Winkle, J; Wulffius-Kock, M1
Burba-Anczewska, I; Danysz, A; Pniewska, A; Pragłowski, T; Wierzba, K; Wutkiewicz, M1
Danysz, A; Pniewska, A; Pragłowski, T; Wierzba, K; Wutkiewicz, M1
Kawabata, N; Kitagawa, H; Kuwamura, T; Satoh, T; Sugiyama, S1
Burba-Anczewska, I; Danysz, A; Kłosiewicz, S; Pniewska, A; Wierzba, K1
Busse, E; Kornhuber, B; Zimmer, G1
Ha, H; Jung, H; Seong, HA1
Kaul, A; Mishra, BJ; Trivedi, P1
Aragão, KS; Brito, GAC; Freire, GE; Freitas, MR; Leitão, RFC; Martins, CDS; Silva, VCD; Wanderley, CWS1
Qiao, LL; Yang, X; Yao, WJ; Zhang, ZQ; Zhao, MX1
Bu, D; Chen, S; Guo, S; Liu, Y; Pan, Y; Wang, P; Wang, X; Yue, T; Zhu, J1
Mohamed, MZ; Mohammed, HH1
Banerji, B; Ghosh, S; Nag, S; Saha, KD1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1

Reviews

1 review(s) available for cysteine and fluorouracil

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Other Studies

20 other study(ies) available for cysteine and fluorouracil

ArticleYear
Effect of L-cysteine on plasma concentration and urinary excretion of 1-(tetrahydro-2-furanyl)-5-fluorouracil metabolites.
    Chemical & pharmaceutical bulletin, 1991, Volume: 39, Issue:4

    Topics: Animals; Cysteine; Fluorouracil; Kidney Tubules; Male; Rats; Rats, Inbred Strains; Tegafur

1991
Enhanced antitumor effect of 5'-deoxy-5-fluorouridine by oral administration with L-cysteine.
    Japanese journal of cancer research : Gann, 1989, Volume: 80, Issue:2

    Topics: Adenocarcinoma; Administration, Oral; Animals; Antineoplastic Combined Chemotherapy Protocols; Chromatography, High Pressure Liquid; Colonic Neoplasms; Cysteine; Drug Synergism; Floxuridine; Fluorouracil; Humans; Injections, Intravenous; Lung Neoplasms; Male; Mice

1989
Potentiation of the chemotherapeutic action of tegafur against solid adenocarcinoma 755 by combination with L-cystine.
    Journal of cancer research and clinical oncology, 1986, Volume: 111, Issue:3

    Topics: Adenocarcinoma; Animals; Antineoplastic Combined Chemotherapy Protocols; Carbon Radioisotopes; Cysteine; Cystine; Drug Synergism; Fluorouracil; Male; Mice; Mice, Inbred Strains; Tegafur

1986
Enhancing effect of bromovinyldeoxyuridine on antitumor activity of 5-fluorouracil and ftorafur against adenocarcinoma 755 in mice.
    European journal of cancer & clinical oncology, 1987, Volume: 23, Issue:6

    Topics: Adenocarcinoma; Animals; Antineoplastic Combined Chemotherapy Protocols; Bromodeoxyuridine; Cysteine; Drug Evaluation, Preclinical; Drug Synergism; Fluorouracil; Male; Mice; Tegafur

1987
Mechanism of potentiation of antitumor activity of 5-fluorouracil against adenocarcinoma 755 by L-cysteine.
    Biochemical pharmacology, 1986, Mar-01, Volume: 35, Issue:5

    Topics: Adenocarcinoma; Animals; Cysteine; DNA, Neoplasm; Dose-Response Relationship, Drug; Drug Synergism; Fluorouracil; Metabolic Clearance Rate; Mice; RNA, Neoplasm

1986
[Studies of cancer radiotherapy by combined use of radioprotectors and a radiosensitizer].
    Nihon Igaku Hoshasen Gakkai zasshi. Nippon acta radiologica, 1973, Volume: 33, Issue:4

    Topics: Animals; beta-Aminoethyl Isothiourea; Cysteine; Fluorouracil; Male; Mercaptoethylamines; Mice; Neoplasms, Experimental; Radiation-Protective Agents; Radiation-Sensitizing Agents; Rats

1973
[Use of radiation sensitizing agents in radiotherapy].
    Strahlentherapie, 1972, Volume: 143, Issue:3

    Topics: Acetates; Anti-Bacterial Agents; Antimetabolites; Antineoplastic Agents; Choline; Cysteine; Fluorouracil; Hematoporphyrins; Humans; Hydrogen Peroxide; Mitosis; Nitrogen Oxides; Oxygen; Periodicity; Quinones; Radiation-Sensitizing Agents; Radiotherapy; Steroids; Thyroid Hormones; Trypan Blue; Urethane; Uridine; Vitamins

1972
[Semiconservative and unscheduled DNA-synthesis of rat thymocytes under the influence of some radioprotecting and radiosensitizing agents (author's transl)].
    Strahlentherapie, 1982, Volume: 158, Issue:2

    Topics: Acetophenones; Animals; beta-Aminoethyl Isothiourea; Bleomycin; Cysteamine; Cysteine; Cytarabine; Ditiocarb; DNA; Doxorubicin; Ethidium; Ethylmaleimide; Female; Fluorouracil; Glutathione; Mercaptoethanol; Metronidazole; Nitrofurazone; Radiation-Protective Agents; Radiation-Sensitizing Agents; Rats; T-Lymphocytes; Tiopronin

1982
Influence of some sulfhydryl compounds on the antineoplastic effectiveness of 5-fluorouracil and 6-mercaptopurine.
    Archivum immunologiae et therapiae experimentalis, 1984, Volume: 32, Issue:3

    Topics: Animals; Cysteine; Drug Synergism; Fluorouracil; Glutathione; Insulin; Leukemia L1210; Mercaptopurine; Mice; Mice, Inbred DBA; Neoplasms, Experimental; Sarcoma 180; Sulfhydryl Compounds

1984
The effect of some sulfhydryl compounds on the toxicity of 5-fluorouracil and 6-mercaptopurine in laboratory animals.
    Acta poloniae pharmaceutica, 1984, Volume: 41, Issue:5

    Topics: Animals; Cysteine; Drug Interactions; Fluorouracil; Glutathione; Insulin; Male; Mercaptopurine; Mice; Mice, Inbred Strains; Rats; Rats, Inbred Strains

1984
Studies to increase the antitumor activity of 1-(tetrahydro-2-furanyl)-5-fluorouracil and its metabolic aspects by combined administration with L-cysteine.
    Japanese journal of pharmacology, 1983, Volume: 33, Issue:4

    Topics: Absorption; Animals; Antineoplastic Agents; Biotransformation; Cysteine; Fluorouracil; Kinetics; Lethal Dose 50; Male; Mice; Microsomes, Liver; Rats; Rats, Inbred Strains; Tegafur

1983
The effect of sulfhydryl compounds on 5-fluorouracil toxicity and distribution.
    Archivum immunologiae et therapiae experimentalis, 1983, Volume: 31, Issue:3

    Topics: Animals; Cysteine; Fluorouracil; Glutathione; Kinetics; Lethal Dose 50; Male; Mesna; Mice; Rats; Rats, Inbred Strains; Sulfhydryl Compounds

1983
Intracellular changes of HeLa cells after single or repeated treatment with cytostatics.
    Arzneimittel-Forschung, 1993, Volume: 43, Issue:3

    Topics: Antineoplastic Agents; Bromodeoxyuridine; Cell Division; Cell Membrane; Cisplatin; Cysteine; Doxorubicin; Fluorouracil; Glutathione; HeLa Cells; Humans; Membrane Fluidity; Membranes; Protein Kinase C

1993
Critical role of cysteine residue 81 of macrophage migration inhibitory factor (MIF) in MIF-induced inhibition of p53 activity.
    The Journal of biological chemistry, 2008, Jul-18, Volume: 283, Issue:29

    Topics: Active Transport, Cell Nucleus; Apoptosis; Cell Line; Cysteine; Doxorubicin; Fluorouracil; Gene Expression Regulation; Humans; Macrophage Migration-Inhibitory Factors; Mutation; Protein Binding; RNA Interference; Transcription, Genetic; Tumor Suppressor Protein p53

2008
L-Cysteine conjugated poly L-lactide nanoparticles containing 5-fluorouracil: formulation, characterization, release and uptake by tissues in vivo.
    Drug delivery, 2015, Volume: 22, Issue:2

    Topics: Animals; Antimetabolites, Antineoplastic; Cell Line; Cell Survival; Cysteine; Drug Carriers; Drug Compounding; Drug Delivery Systems; Fluorouracil; Half-Life; Lung; Male; Metabolic Clearance Rate; Mice, Inbred BALB C; Nanoparticles; Particle Size; Poloxamer; Polyesters; Rats; Solubility; Surface Properties; Tissue Distribution

2015
Role of the route of leukotrienes in an experimental model of oral mucositis induced by 5-fluorouracil 1.
    Acta cirurgica brasileira, 2017, Volume: 32, Issue:9

    Topics: Animals; Cricetinae; Cysteine; Cytokines; Disease Models, Animal; Fluorouracil; Immunohistochemistry; Leukotrienes; Male; Stomatitis

2017
The Biological Activity Research of the Nano-Drugs Based on 5-Fluorouracil-Modified Quantum Dots.
    International journal of nanomedicine, 2020, Volume: 15

    Topics: Antimetabolites, Antineoplastic; Cell Proliferation; Cysteine; Drug Carriers; Ethylenediamines; Fluorouracil; HeLa Cells; Hep G2 Cells; Humans; Membrane Potential, Mitochondrial; Microscopy, Electron, Transmission; Microscopy, Fluorescence; Quantum Dots; Reactive Oxygen Species; Spectrophotometry, Ultraviolet

2020
Endogenous hydrogen sulfide regulates xCT stability through persulfidation of OTUB1 at cysteine 91 in colon cancer cells.
    Neoplasia (New York, N.Y.), 2021, Volume: 23, Issue:5

    Topics: Amino Acid Transport System y+; Animals; Cell Line, Tumor; Colonic Neoplasms; Cysteine; Deubiquitinating Enzymes; Disease Models, Animal; Fluorouracil; Gene Expression; Gene Expression Regulation, Neoplastic; Humans; Hydrogen Sulfide; Immunohistochemistry; Mice; Models, Biological; Protein Binding; Protein Processing, Post-Translational; Protein Stability; Synthetic Lethal Mutations; Tissue Array Analysis

2021
Rupatadine protects the intestinal mucosa from injury by 5-flurouracil via modulation of inflammation, apoptosis and intestinal permeability.
    Drug and chemical toxicology, 2022, Volume: 45, Issue:6

    Topics: Animals; Apoptosis; Aspartic Acid Proteases; Carboxymethylcellulose Sodium; Caspase 3; Cysteine; Fluorouracil; Glutathione; Histamine; Inflammation; Interleukin-10; Interleukin-1beta; Interleukin-6; Intestinal Mucosa; Irritants; Male; Malondialdehyde; NF-kappa B; Nitric Oxide; Permeability; Peroxidase; Rats; Rats, Wistar; Tumor Necrosis Factor-alpha

2022
S-Benzyl cysteine based cyclic dipeptide super hydrogelator: Enhancing efficacy of an anticancer drug via sustainable release.
    Journal of peptide science : an official publication of the European Peptide Society, 2022, Volume: 28, Issue:8

    Topics: Antineoplastic Agents; Cysteine; Dipeptides; Fluorouracil; Humans; Hydrogels; Peptides; Spectroscopy, Fourier Transform Infrared

2022