cysteine and fibrin

cysteine has been researched along with fibrin in 41 studies

Research

Studies (41)

Timeframe	Studies, this research(%)	All Research%
pre-1990	24 (58.54)	18.7374
1990's	8 (19.51)	18.2507
2000's	6 (14.63)	29.6817
2010's	2 (4.88)	24.3611
2020's	1 (2.44)	2.80

Authors

Authors	Studies
Asakura, S; Hirata, H; Matsuda, M; Morita, K; Shirakawa, S; Wada, H; Yamazumi, K; Yoshida, N	1
Hirata, H; Matsuda, M; Miyata, T; Shimonishi, Y; Takao, T; Takeda, Y; Terukina, S	1
Matsuda, M; Moroi, M; Ota, K; Yoshida, N	1
Gladner, JA; Halver, JE; Lewis, MS; Murtaugh, PA	1
Yamada, Z	1
Marshall, FN; Massad, EN	1
Host, WR; Rush, BF; Serlin, O	1
Inoshita, K; Shanberge, JN	1
Maldyk, E	1
Ostrowski, L	2
Fabián, J	1
Edman, P; Henschen, A	1
Chen, R; Doolittle, RF; Lau, F	1
Cooper, IA; Firkin, BG	1
Janssen, CL; Masure, R	1
Khodorova, EL; Smekhova, EA; Svechnikova, TA	1
Barlow, GH; Holleman, WH; Lorand, L	1
Buluk, K; Olbromski, J; Zuch, A	1
Bleyl, U; Kuhn, W; Sebening, H	1
Corcoran, DH; Ferguson, EW; Fretto, LJ; McKee, PA	1
Baudo, F; Bögli, C; Furlan, M; Heinemann, G; Jungo, M; Lämmle, B; Redaelli, R; Steinmann, C; Wermuth, B	2
Galibert, F; Hamelin, J; Orsini, G; Sarmientos, P	1
Arcila, P; Bennett, WF; Berleau, LT; Keyt, BA; Nguyen, HV; Sehl, LC	1
Brennan, SO; George, PM; Hammonds, B; Spearing, R	1
Foster, DC; Linde, V; Nielsen, LS; Petersen, LC	1
Egbring, R; Kohno, I; Matsuda, M; Nakamikawa, C; Sugo, T; Takebe, M	1
Chen, X; Du, XY; Liu, JW; Liu, P; Wu, XF; Xu, JM; Zhou, YC	1
Coates, AI; Hantgan, RR; Henschen-Edman, AH; Lefkowitz, JB; Lord, ST; Lounes, KC	1
MORSE, BS; NUSSBAUM, M	1
KONISHI, K; LORAND, L	1
GORMSEN, J; SIVERTSEN, U	1
WEBB, WR	1
Hirota-Kawadobora, M; Ishii, K; Ishikawa, S; Okumura, N; Terasawa, F; Tozuka, M	1
Fujihara, N; Hirota-Kawadobora, M; Kani, S; Okumura, N; Terasawa, F; Tozuka, M; Yamauchi, K	1
Dávid, M; Habon, T; Keszthelyi, Z; Kovács, N; Losonczy, H; Nagy, A; Tóth, O	1
Engelmann, B; Manukyan, D; Massberg, S; von Bruehl, ML	1
Adamson, PJ; Ariëns, RAS; Goldsberry, WN; Grant, PJ; Hethershaw, EL; Maurer, MC; Pease, RJ; Philippou, H; Radford, SE; Smith, KA	1
Banerjee, K; Gruschus, JM; Medved, L; Tjandra, N; Yakovlev, S	1
Beilfuss, N; Puts, R; Raum, K; Zabarylo, U; Zhang, H	1

Reviews

3 review(s) available for cysteine and fibrin

Article	Year
[Structure and origin of fibrinoid]. Reumatologia, 1969, Volume: 7, Issue:2 Topics: Collagen Diseases; Cysteine; Extracellular Space; Fibrin; Humans; Rheumatoid Nodule; Shwartzman Phenomenon; Tryptophan; Tyrosine	1969
[Type I antithrombin deficiency as a cause of arterial and venous thrombosis in a family with severe thrombophilia]. Orvosi hetilap, 2005, Oct-09, Volume: 146, Issue:41 Topics: Adult; C-Reactive Protein; Cholesterol; Cysteine; Female; Fibrin; Genetic Predisposition to Disease; Homocysteine; Humans; Male; Pedigree; Plasminogen Activator Inhibitor 1; Polymorphism, Genetic; Risk Factors; Threonine; Thrombophilia; Thrombosis; Venous Thrombosis; von Willebrand Factor	2005
Protein disulfide isomerase as a trigger for tissue factor-dependent fibrin generation. Thrombosis research, 2008, Volume: 122 Suppl 1 Topics: Animals; Cysteine; Disulfides; Fibrin; Glutathione; Humans; Mice; Protein Disulfide-Isomerases; Thromboplastin	2008

Other Studies

38 other study(ies) available for cysteine and fibrin

Article	Year
A new congenital abnormal fibrinogen Ise characterized by the replacement of B beta glycine-15 by cysteine. Blood, 1991, May-01, Volume: 77, Issue:9 Topics: Amino Acid Sequence; Batroxobin; Blood Coagulation Disorders; Blood Coagulation Tests; Chromatography, High Pressure Liquid; Cysteine; Fibrin; Fibrinogens, Abnormal; Fibrinopeptide A; Fibrinopeptide B; Glycine; Humans; Male; Middle Aged; Molecular Sequence Data; Thrombin	1991
Substitution of gamma Arg-275 by Cys in an abnormal fibrinogen, "fibrinogen Osaka II". Evidence for a unique solitary cystine structure at the mutation site. The Journal of biological chemistry, 1988, Sep-25, Volume: 263, Issue:27 Topics: Adolescent; Aged; Amino Acid Sequence; Amino Acids; Arginine; Blood Coagulation Disorders; Calcium; Chromatography, High Pressure Liquid; Cysteine; Cystine; Egtazic Acid; Electrophoresis, Polyacrylamide Gel; Female; Fibrin; Fibrinogen; Fibrinogens, Abnormal; Fibrinolysin; Humans; Male; Molecular Sequence Data; Mutation; Peptide Fragments; Serine Endopeptidases; Thrombin Time	1988
An apparently higher molecular weight gamma-chain variant in a new congenital abnormal fibrinogen Tochigi characterized by the replacement of gamma arginine-275 by cysteine. Blood, 1988, Volume: 71, Issue:2 Topics: Arginine; Blood Coagulation; Cysteine; Fibrin; Fibrinogen; Humans; Male; Middle Aged; Molecular Weight; Mutation; Peptide Fragments; Polymers; Structure-Activity Relationship	1988
Cross-linking reactions of lamprey fibrinogen and fibrin. Biochimica et biophysica acta, 1974, Aug-08, Volume: 359, Issue:2 Topics: Animals; Binding Sites; Blood Coagulation; Calcium; Cysteine; Drug Stability; Edetic Acid; Electrophoresis, Polyacrylamide Gel; Ethanol; Factor XIII; Fibrin; Fibrinogen; Fishes; Freezing; Humans; Isoflurophate; Macromolecular Substances; Molecular Weight; Protein Binding; Protein Conformation; Species Specificity; Time Factors	1974
[Fibrinolysis activities and factor XIII in the neonatal period. 2. Relationship between factor XIII and fibrinolysis activities]. Nihon Shonika Gakkai zasshi. Acta paediatrica Japonica, 1971, Volume: 75, Issue:4 Topics: Animals; Cyclohexanecarboxylic Acids; Cysteine; Embryo, Mammalian; Factor XIII; Female; Fibrin; Fibrinolysin; Fibrinolysis; Humans; Infant, Newborn; Liver Diseases; Pregnancy; Rabbits	1971
Interference with fibrin stabilization by polymyxin B sulfate. Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1967, Volume: 125, Issue:2 Topics: Animals; Blood Coagulation; Blood Coagulation Factors; Cysteine; Dogs; Factor XIII; Fibrin; In Vitro Techniques; Polymyxins	1967
Hyperalimentation in cirrhotic patients. American journal of surgery, 1972, Volume: 123, Issue:1 Topics: Acid-Base Equilibrium; Acidosis; Alanine Transaminase; Alkaline Phosphatase; Amino Acids; Ammonia; Arginine; Carbon Dioxide; Caseins; Catheterization; Cysteine; Diet Therapy; Fibrin; Glutamine; Glycine; Histidine; Humans; Isoleucine; Leucine; Liver; Liver Cirrhosis; Lysine; Methionine; Parenteral Nutrition; Phenylalanine; Potassium; Sodium; Threonine; Tryptophan	1972
A rapid quantitative assay method for fibrin-stabilizing factor (factor XIII). American journal of clinical pathology, 1974, Volume: 61, Issue:1 Topics: Acetates; Adult; Amidinotransferases; Biological Assay; Blood Coagulation; Clot Retraction; Cysteine; Factor VIII; Fibrin; Fibrinogen; Humans; Methods; Solutions; Toluidines	1974
[Effect of cysteine and hemolyzed erythrocytes on the properties of clotted fibrin]. Roczniki Akademii Medycznej im. Juliana Marchlewskiego w Bialymstoku, 1964, Volume: 10 Topics: Blood Coagulation; Cysteine; Erythrocytes; Fibrin; Hemolysis; In Vitro Techniques; Sulfhydryl Compounds	1964
Purification and some properties of the extracellular protease of Bacillus pumilus. Folia microbiologica, 1970, Volume: 15, Issue:3 Topics: Bacillus; Caseins; Chemical Precipitation; Chloromercuribenzoates; Chromatography, DEAE-Cellulose; Cysteine; Edetic Acid; Ethanol; Fibrin; Hot Temperature; Hydrogen-Ion Concentration; Immunoelectrophoresis; Ions; Metals; Peptide Hydrolases; Protease Inhibitors; Ultracentrifugation	1970
Large scale preparation of S-carboxymethylated chains of human fibrin and fibrinogen and the occurrence of -chain variants. Biochimica et biophysica acta, 1972, Apr-15, Volume: 263, Issue:2 Topics: Alkylation; Amino Acid Sequence; Amino Acids; Chemical Phenomena; Chemistry; Chromatography, Gel; Chromatography, Ion Exchange; Cysteine; Electrophoresis, Paper; Fibrin; Fibrinogen; Genetic Variation; Humans; Hydrogen-Ion Concentration; Iodoacetates; Mercaptoethanol; Methionine; Molecular Weight; Oxidation-Reduction; Peptides; Protein Conformation; Thiocyanates; Thrombin; Urea	1972
Hybrid fibrin: proof of the intermolecular nature of - crosslinking units. Biochemical and biophysical research communications, 1971, Jul-02, Volume: 44, Issue:1 Topics: Animals; Binding Sites; Calcium Chloride; Carbon Isotopes; Cattle; Chemical Phenomena; Chemistry; Chromatography, Gel; Chromatography, Ion Exchange; Cysteine; Dialysis; Electrophoresis, Paper; Ethanol; Fibrin; Fibrinogen; Glutamates; Glycine; Humans; Lysine; Methods; Protein Binding; Sulfites; Thrombin; Trypsin; Urea	1971
Amino acid transport into human platelets and subsequent incorporation into protein. Thrombosis et diathesis haemorrhagica, 1970, Feb-28, Volume: 23, Issue:1 Topics: Amino Acids; Biological Transport; Blood Platelets; Blood Proteins; Carbon Isotopes; Cell Membrane; Cysteine; Fibrin; Fibrinogen; Glutamates; Humans; Leucine; Lysine; Microscopy, Electron; Mitochondria; Proline; Puromycin; Serine; Thrombin; Valine	1970
Enzymatic method for the quantitative determination of factor. XIII. Application to a familial deficiency. Pathologia Europaea, 1970, Volume: 5, Issue:3 Topics: Adult; Blood Coagulation Disorders; Blood Coagulation Tests; Blood Platelets; Cysteine; Factor XIII; Female; Fibrin; Fibrinogen; Humans; Male; Methods; Solubility; Time Factors	1970
[Method for determination of the activity of the fibrin stabilizing factor]. Ukrains'kyi biokhimichnyi zhurnal, 1970, Volume: 42, Issue:5 Topics: Blood Coagulation; Blood Platelets; Calcium Chloride; Cysteine; Factor XIII; Fibrin; Humans	1970
The action of Arvin on Fibrin Stabilizing Factor (factor 13). Research communications in chemical pathology and pharmacology, 1970, Volume: 1, Issue:1 Topics: Acetates; Animals; Arginine; Blood Coagulation; Calcium Chloride; Chlorine; Cysteine; Esters; Factor XIII; Fibrin; Polymers; Snakes; Thrombin; Tosyl Compounds; Venoms	1970
On the physical properties of fibrin clots during desmofibrinogenesis. Archivum immunologiae et therapiae experimentalis, 1968, Volume: 16, Issue:1 Topics: Biophysical Phenomena; Biophysics; Blood Coagulation; Blood Coagulation Factors; Calcium; Cysteine; Elasticity; Fibrin; Hemoglobins; Sulfhydryl Compounds	1968
[Morphologic demonstration of fibrin monomers in histogic sections]. Thrombosis et diathesis haemorrhagica, 1969, Aug-31, Volume: 22, Issue:1 Topics: Amidines; Animals; Benzene Derivatives; Benzoates; Blood Coagulation Tests; Cysteine; Esters; Ethanol; Factor XIII; Fibrin; Formaldehyde; Glycine; Histocytochemistry; Kidney; Liver; Lung; Rabbits; Shwartzman Phenomenon; Spleen	1969
Effect of cysteine and hemolyzed erythrocytes on the properties of clotted fibrin. Polish medical journal, 1966, Volume: 5, Issue:6 Topics: Animals; Blood Coagulation; Blood Coagulation Factors; Buffers; Calcium Chloride; Cattle; Cysteine; Fibrin; Fibrinogen; Hemoglobins; Hemolysis; Sulfhydryl Compounds; Thrombelastography; Thrombin	1966
Localization of a cross-link donor site in the alpha-chain of human fibrin. Thrombosis research, 1980, Sep-15, Volume: 19, Issue:6 Topics: Alanine; Amino Acid Sequence; Cross-Linking Reagents; Cyanogen Bromide; Cysteine; Fibrin; Fibrinogen; Lysine; Peptides; Threonine; Valine	1980
Fibrinogen Milano V: a congenital dysfibrinogenaemia with a gamma 275 Arg-->Cys substitution. Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis, 1994, Volume: 5, Issue:4 Topics: Afibrinogenemia; Amino Acid Sequence; Base Sequence; Blood Coagulation Tests; Cysteamine; Cysteine; Exons; Female; Fibrin; Fibrinogens, Abnormal; Humans; Middle Aged; Molecular Sequence Data; Nephelometry and Turbidimetry; Polymerase Chain Reaction; Sulfhydryl Compounds; Thrombin	1994
A new substitution, gamma 358 Ser-->Cys, in fibrinogen Milano VII causes defective fibrin polymerization. Blood, 1994, Sep-15, Volume: 84, Issue:6 Topics: Adult; Albumins; Base Sequence; Cysteine; Electrophoresis, Polyacrylamide Gel; Female; Fibrin; Fibrinogens, Abnormal; Humans; Immunoblotting; Kinetics; Male; Mercaptoethanol; Molecular Sequence Data; Mutation; Pedigree; Polymerase Chain Reaction; Polymers; Sequence Analysis, DNA; Serine	1994
Implication of cysteine residues in the activity of single-chain urokinase-plasminogen activator. Biochemical and biophysical research communications, 1993, Jul-30, Volume: 194, Issue:2 Topics: Amino Acid Sequence; Base Sequence; Cloning, Molecular; Cysteine; Disulfides; Electrophoresis, Polyacrylamide Gel; Escherichia coli; Fibrin; Fibrinolysis; Humans; Molecular Sequence Data; Mutagenesis, Site-Directed; Oligodeoxyribonucleotides; Recombinant Proteins; Restriction Mapping; Urokinase-Type Plasminogen Activator	1993
Locating the unpaired cysteine of tissue-type plasminogen activator. Protein engineering, 1996, Volume: 9, Issue:3 Topics: Amino Acid Sequence; Animals; Antibodies, Monoclonal; Binding Sites; Cell Line; Computer Graphics; Cricetinae; Cysteine; Embryo, Mammalian; Epidermal Growth Factor; Fibrin; Genetic Variation; Humans; Kidney; Mice; Mice, Inbred ICR; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Point Mutation; Protein Structure, Secondary; Recombinant Proteins; Sequence Homology, Amino Acid; Tissue Plasminogen Activator; Transfection	1996
Electrospray ionisation mass spectrometry facilitates detection of fibrinogen (Bbeta 14 Arg --> Cys) mutation in a family with thrombosis. Thrombosis and haemostasis, 1997, Volume: 78, Issue:6 Topics: Adult; Amino Acid Substitution; Arginine; Catalysis; Cysteine; Family Health; Female; Fibrin; Fibrinogen; Fibrinopeptide A; Fibrinopeptide B; Glycoproteins; Heterozygote; Humans; Mass Spectrometry; Molecular Weight; Mutation; Point Mutation; Polymerase Chain Reaction; Sequence Analysis; Thrombin; Thrombosis	1997
Elimination of the Cys558-Cys566 bond in Lys78-plasminogen--effect on activation and fibrin interaction. European journal of biochemistry, 1998, Jan-15, Volume: 251, Issue:1-2 Topics: Animals; Cricetinae; Cysteine; Disulfides; Electrophoresis, Polyacrylamide Gel; Enzyme Activation; Fibrin; Fibrinolysin; Lysine; Plasminogen; Recombinant Proteins; Serine; Serine Endopeptidases; Streptokinase; Tissue Plasminogen Activator; Urokinase-Type Plasminogen Activator	1998
Factor XIIIa cross-linking of the Marburg fibrin: formation of alpham.gamman-heteromultimers and the alpha-chain-linked albumin. gamma complex, and disturbed protofibril assembly resulting in acquisition of plasmin resistance relevant to thrombophila. Blood, 1998, May-01, Volume: 91, Issue:9 Topics: alpha-2-Antiplasmin; Cysteine; Disulfides; Enzyme Activation; Factor XIII; Fibrin; Fibrinogens, Abnormal; Fibrinolysin; Humans; Macromolecular Substances; Polymers; Serum Albumin; Thrombosis; Tissue Plasminogen Activator	1998
Purification, characterization, and cDNA sequence of halysetin, a disintegrin-like/cysteine-rich protein from the venom of Agkistrodon halys Pallas. Biochemical and biophysical research communications, 2000, Nov-11, Volume: 278, Issue:1 Topics: Adenosine Diphosphate; Agkistrodon; Amino Acid Sequence; Animals; Base Sequence; Chromatography, Agarose; Chromatography, Liquid; Collagen; Cysteine; Disintegrins; DNA, Complementary; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Esterases; Fibrin; Fibrinogen; Hydrogen-Ion Concentration; Isoelectric Focusing; Mass Spectrometry; Molecular Sequence Data; Phospholipases A; Phospholipases A2; Platelet Aggregation; Reverse Transcriptase Polymerase Chain Reaction; RNA; Sequence Analysis, DNA; Sequence Homology, Amino Acid; Snake Venoms; Viper Venoms	2000
The impaired polymerization of fibrinogen Longmont (Bbeta166Arg-->Cys) is not improved by removal of disulfide-linked dimers from a mixture of dimers and cysteine-linked monomers. Blood, 2001, Aug-01, Volume: 98, Issue:3 Topics: Adult; Amino Acid Substitution; Cysteine; Dimerization; Disulfides; Female; Fibrin; Fibrinogens, Abnormal; Fibrinolysin; Humans; Kinetics; Molecular Weight; Polymers; Thrombin	2001
PLASMA FIBRIN STABILIZING FACTOR ACTIVITY IN VARIOUS DISEASES. Blood, 1964, Volume: 23 Topics: Alpha-Globulins; Anemia; Biological Assay; Biomedical Research; Blood Coagulation; Blood Coagulation Factors; Calcium; Collagen Diseases; Cysteine; Factor XIII; Fibrin; Hemorrhagic Disorders; Humans; Leukemia; Liver; Liver Diseases; Lymphoma; Neoplasms; Pathology; Serum Globulins; Sulfhydryl Compounds; Thrombin	1964
ACTIVATION OF THE FIBRIN STABILIZING FACTOR OF PLASMA BY THROMBIN. Archives of biochemistry and biophysics, 1964, Volume: 105 Topics: Blood Coagulation; Calcium; Calcium, Dietary; Cysteine; Factor XIII; Fibrin; Glucose; Humans; Peptide Hydrolases; Research; Thrombin	1964
THE EFFECT OF SULFHYDRYLINHIBITORS AND GLYCINE DERIVATIVES ON FIBRIN POLYMERIZATION AND THE PHYSICAL STRENGTH OF FIBRIN IN PLASMA. Thrombosis et diathesis haemorrhagica, 1964, Jul-31, Volume: 11 Topics: Amides; Anesthetics, Local; Benzoates; Blood Coagulation; Chloromercuribenzoates; Cysteine; Edetic Acid; Fibrin; Glycine; Iodoacetates; Pharmacology; Plasma; Polymerization; Pyrroles; Sulfhydryl Compounds; Thrombelastography	1964
NEW MUCOLYTIC AGENTS FOR SPUTUM LIQUEFACTION. Postgraduate medicine, 1964, Volume: 36 Topics: Acetylcysteine; Asthma; Bronchial Diseases; Cysteine; Cystic Fibrosis; Expectorants; Fibrin; Humans; Lung Diseases; Mucus; Sputum; Toxicology	1964
Recombinant fibrinogen, gamma275Arg-->Cys, exhibits formation of disulfide bond with cysteine and severely impaired D:D interactions. Journal of thrombosis and haemostasis : JTH, 2004, Volume: 2, Issue:3 Topics: Amino Acid Substitution; Arginine; Base Sequence; Binding Sites; Catalysis; Cysteine; Disulfides; DNA Primers; Factor XIIIa; Fibrin; Fibrinogen; Humans; Kinetics; Microscopy, Electron, Scanning; Molecular Weight; Mutagenesis, Site-Directed; Recombinant Proteins; Thrombin	2004
Functional analysis of recombinant Bbeta15C and Bbeta15A fibrinogens demonstrates that Bbeta15G residue plays important roles in FPB release and in lateral aggregation of protofibrils. Journal of thrombosis and haemostasis : JTH, 2005, Volume: 3, Issue:5 Topics: Alanine; Animals; Batroxobin; Blotting, Western; Catalysis; Chromatography, High Pressure Liquid; Cysteine; Dimerization; Disulfides; Electrophoresis, Polyacrylamide Gel; Fibrin; Fibrinogen; Fibrinopeptide B; Glycine; Heterozygote; Humans; Immunoblotting; Kinetics; Microscopy, Electron, Scanning; Mutagenesis; Protein Binding; Recombinant Proteins; Snake Venoms; Thrombin; Time Factors	2005
The role of β-barrels 1 and 2 in the enzymatic activity of factor XIII A-subunit. Journal of thrombosis and haemostasis : JTH, 2018, Volume: 16, Issue:7 Topics: Catalytic Domain; Cysteine; Enzyme Activation; Factor XIII; Fibrin; Fibrinolysis; Humans; Kinetics; Mutation; Protein Domains; Protein Structure, Secondary; Protein Structure, Tertiary; Recombinant Proteins; Structure-Activity Relationship; Substrate Specificity	2018
Nuclear Magnetic Resonance Solution Structure of the Recombinant Fragment Containing Three Fibrin-Binding Cysteine-Rich Domains of the Very Low Density Lipoprotein Receptor. Biochemistry, 2018, 07-31, Volume: 57, Issue:30 Topics: Amino Acid Sequence; Binding Sites; Cysteine; Fibrin; Humans; Models, Molecular; Nuclear Magnetic Resonance, Biomolecular; Protein Domains; Protein Structure, Secondary; Receptors, LDL; Recombinant Proteins	2018
A Tissue Engineering Acoustophoretic (TEA) Set-up for the Enhanced Osteogenic Differentiation of Murine Mesenchymal Stromal Cells (mMSCs). International journal of molecular sciences, 2022, Sep-29, Volume: 23, Issue:19 Topics: Animals; Cell Differentiation; Cells, Cultured; Collagen Type I; Core Binding Factor Alpha 1 Subunit; Cyclin D1; Cysteine; Fibrin; Humans; Hydrogels; Mesenchymal Stem Cells; Mice; Osteocalcin; Osteogenesis; Osteonectin; Osteopontin; Tissue Engineering; Tissue Scaffolds	2022