cysteine and dimethyl fumarate

cysteine has been researched along with dimethyl fumarate in 12 studies

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's10 (83.33)24.3611
2020's2 (16.67)2.80

Authors

AuthorsStudies
Brennan, MS; Gao, B; Hronowski, X; Juhasz, P; Li, B; Matos, MF; Rhodes, KJ; Scannevin, RH1
Alvarado-Kristensson, M; Crneta, E; Hellsten, R; Lehn, S; Lindström, L; Nilsson, E; Olsson, R; Villoutreix, BO1
Calderon-Gierszal, EL; El-Shennawy, L; Frasor, J; Georgieva, G; Kastrati, I; Siklos, MI; Thatcher, GR; Thayer, EN1
Altman, A; Backus, KM; Blewett, MM; Cravatt, BF; Teijaro, JR; Xie, J; Zaro, BW1
Bhargava, P; Calabresi, PA; Kim, PM; Kornberg, MD; Putluri, N; Putluri, V; Snowman, AM; Snyder, SH1
Andersen, JL; Arthur, JSC; Funder, ED; Gesser, B; Gotfred-Rasmussen, H; Gothelf, KV; Iversen, L; Nielsen, CJF; Nissen, P; Rasmussen, MK; Toth, R1
Frizzell, N; Galloway, A; Lanci, SA; Manuel, AM; Ortinski, PI; Patel, T; Piroli, GG; Shi, L; Smith, DS; Walla, MD; Wang, J1
Benetti, E; Boscaro, V; Cangemi, L; Dianzani, C; Gallicchio, M; Miglio, G; Rosa, AC1
Basagni, F; Lanni, C; Minarini, A; Rosini, M1
Andrade, J; Neel, BG; Ueberheide, B; Xu, Y1
Dutta, R; Fitzgerald, KA; Humphries, F; Ionete, C; Jiang, Z; Ketelut-Carneiro, N; Khalighinejad, F; Li, S; Muneeruddin, K; Nemmara, VV; Pesiridis, S; Shaffer, SA; Shmuel-Galia, L; Thompson, PR; Wang, B; Wilson, R; Yang, S1
Davies, MJ; Sauerland, MB1

Reviews

2 review(s) available for cysteine and dimethyl fumarate

ArticleYear
Lights and shadows of electrophile signaling: focus on the Nrf2-Keap1 pathway.
    Future medicinal chemistry, 2019, Volume: 11, Issue:7

    Topics: Animals; Antioxidants; Cysteine; Dimethyl Fumarate; Drug Design; Humans; Kelch-Like ECH-Associated Protein 1; Molecular Structure; NF-E2-Related Factor 2; Oleanolic Acid; Oxidation-Reduction; Oxidative Stress; Signal Transduction; Structure-Activity Relationship

2019
Electrophile versus oxidant modification of cysteine residues: Kinetics as a key driver of protein modification.
    Archives of biochemistry and biophysics, 2022, 09-30, Volume: 727

    Topics: Acrolein; Aldehydes; Cysteine; Dimethyl Fumarate; Humans; Hydrogen Peroxide; Kinetics; Oxidants

2022

Other Studies

10 other study(ies) available for cysteine and dimethyl fumarate

ArticleYear
Dimethyl fumarate and monoethyl fumarate exhibit differential effects on KEAP1, NRF2 activation, and glutathione depletion in vitro.
    PloS one, 2015, Volume: 10, Issue:3

    Topics: Astrocytes; Cell Nucleus; Cysteine; Dimethyl Fumarate; Extracellular Space; Fumarates; Gene Expression Regulation; Glutathione; HEK293 Cells; Humans; Intracellular Signaling Peptides and Proteins; Kelch-Like ECH-Associated Protein 1; NF-E2-Related Factor 2; Protein Transport

2015
Therapeutic Targeting of Nuclear γ-Tubulin in RB1-Negative Tumors.
    Molecular cancer research : MCR, 2015, Volume: 13, Issue:7

    Topics: Acetals; Acyclic Monoterpenes; Animals; Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Cysteine; Dimethyl Fumarate; E2F Transcription Factors; Guanosine Triphosphate; Heterografts; Mice; Microtubules; Monoterpenes; Nuclear Proteins; Retinoblastoma Protein; Tubulin; Tubulin Modulators

2015
Dimethyl Fumarate Inhibits the Nuclear Factor κB Pathway in Breast Cancer Cells by Covalent Modification of p65 Protein.
    The Journal of biological chemistry, 2016, Feb-12, Volume: 291, Issue:7

    Topics: Active Transport, Cell Nucleus; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Cysteine; Dimethyl Fumarate; Female; Gene Expression Regulation, Neoplastic; Genes, Reporter; Humans; Mice, Nude; Neoplasm Proteins; Neoplastic Stem Cells; NF-kappa B; Random Allocation; Signal Transduction; Transcription Factor RelA; Tumor Burden; Xenograft Model Antitumor Assays

2016
Chemical proteomic map of dimethyl fumarate-sensitive cysteines in primary human T cells.
    Science signaling, 2016, 09-13, Volume: 9, Issue:445

    Topics: Animals; CD28 Antigens; Cysteine; Dimethyl Fumarate; Humans; Lymphocyte Activation; Mice; Mice, Knockout; Protein Kinase C; Proteome; Proteomics; T-Lymphocytes

2016
Dimethyl fumarate targets GAPDH and aerobic glycolysis to modulate immunity.
    Science (New York, N.Y.), 2018, 04-27, Volume: 360, Issue:6387

    Topics: Animals; Autoimmune Diseases; Autoimmunity; Citric Acid Cycle; Cysteine; Dimethyl Fumarate; Glyceraldehyde-3-Phosphate Dehydrogenase (Phosphorylating); Glycolysis; Humans; Immunosuppressive Agents; Lymphocytes; Mice; Mice, Inbred C57BL; Myeloid Cells; Succinates

2018
Dimethyl fumarate is an allosteric covalent inhibitor of the p90 ribosomal S6 kinases.
    Nature communications, 2018, 10-19, Volume: 9, Issue:1

    Topics: Animals; Binding Sites; Binding, Competitive; Crystallography, X-Ray; Cysteine; Dimethyl Fumarate; HEK293 Cells; Humans; Mice; Models, Molecular; Mutation; Ribosomal Protein S6 Kinases, 90-kDa

2018
Identification of Novel Protein Targets of Dimethyl Fumarate Modification in Neurons and Astrocytes Reveals Actions Independent of Nrf2 Stabilization.
    Molecular & cellular proteomics : MCP, 2019, Volume: 18, Issue:3

    Topics: 3T3-L1 Cells; Animals; Astrocytes; Cells, Cultured; Cofilin 1; Cysteine; Dimethyl Fumarate; Intercellular Signaling Peptides and Proteins; Mass Spectrometry; Mice; Nerve Tissue Proteins; Neurons; NF-E2-Related Factor 2; Rats; Tubulin

2019
Analyzing Cysteine Site Neighbors in Proteins to Reveal Dimethyl Fumarate Targets.
    Proteomics, 2019, Volume: 19, Issue:4

    Topics: Cysteine; Dimethyl Fumarate; Humans; Proteins

2019
Activated Thiol Sepharose-based proteomic approach to quantify reversible protein oxidation.
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2019, Volume: 33, Issue:11

    Topics: Animals; Carrier Proteins; Cells, Cultured; Cysteine; Dimethyl Fumarate; Fumarate Hydratase; Membrane Proteins; Metabolism, Inborn Errors; Muscle Hypotonia; Oxidation-Reduction; Proteins; Proteomics; Psychomotor Disorders; Rats; Sepharose; Thyroid Hormone-Binding Proteins; Thyroid Hormones

2019
Succination inactivates gasdermin D and blocks pyroptosis.
    Science (New York, N.Y.), 2020, 09-25, Volume: 369, Issue:6511

    Topics: Animals; Caspases; Citric Acid Cycle; Cysteine; Dimethyl Fumarate; Encephalomyelitis, Autoimmune, Experimental; Familial Mediterranean Fever; Female; HEK293 Cells; Humans; Inflammasomes; Intracellular Signaling Peptides and Proteins; Lipopolysaccharides; Macrophage Activation; Macrophages; Male; Mice; Mice, Inbred C57BL; Mice, Mutant Strains; Multiple Sclerosis; Phosphate-Binding Proteins; Protein Processing, Post-Translational; Pyroptosis

2020