Compounds > cysteine

cysteine and clozapine

cysteine has been researched along with clozapine in 8 studies

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (12.50)18.2507
2000's3 (37.50)29.6817
2010's4 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Breier, A; Buchanan, RW; Clifton, A; Goldman, D; Malhotra, AK; Ozaki, N; Pickar, D; Rooney, W1
Einsiedel, J; Gmeiner, P; Hübner, H1
Benedetti, F; Cavallaro, R; Cocchi, F; Lattuada, E; Lorenzi, C; Smeraldi, E1
Chiba, M; Inoue, K; Ishii, Y; Ohe, T; Shibata, Y; Takahashi, H1
Boerma, JS; Commandeur, JN; Vermeulen, NP1
Liu, X; Penner, N; Prakash, C1
Fukuda, K; Inoue, K; Kusano, K; Yoshimura, T1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1

Reviews

1 review(s) available for cysteine and clozapine

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Other Studies

7 other study(ies) available for cysteine and clozapine

ArticleYear
Clozapine response and the 5HT2C Cys23Ser polymorphism.
    Neuroreport, 1996, Sep-02, Volume: 7, Issue:13

    Topics: Alleles; Antipsychotic Agents; Base Sequence; Clozapine; Cysteine; DNA Primers; Female; Genetic Carrier Screening; Homozygote; Humans; Male; Polymerase Chain Reaction; Polymorphism, Restriction Fragment Length; Predictive Value of Tests; Psychotic Disorders; Receptor, Serotonin, 5-HT2C; Receptors, Serotonin; Schizophrenia; Serine

1996
Benzamide bioisosteres incorporating dihydroheteroazole substructures: EPC synthesis and SAR leading to a selective dopamine D4 receptor partial agonist (FAUC 179).
    Bioorganic & medicinal chemistry letters, 2001, Sep-17, Volume: 11, Issue:18

    Topics: Animals; Biochemistry; Cattle; CHO Cells; Clozapine; Cricetinae; Cysteine; Dopamine Antagonists; Drug Design; Humans; In Vitro Techniques; Indoles; Magnetic Resonance Spectroscopy; Molecular Structure; Quinpirole; Receptors, Dopamine D2; Receptors, Dopamine D4; Serine; Spiperone; Stereoisomerism; Structure-Activity Relationship; Threonine

2001
Genetic dissection of drug effects in clinical practice: CLOCK gene and clozapine-induced diurnal sleepiness.
    Neuroscience letters, 2004, Sep-02, Volume: 367, Issue:2

    Topics: Adult; Antipsychotic Agents; Chi-Square Distribution; Chromatography, High Pressure Liquid; CLOCK Proteins; Clozapine; Cysteine; Disorders of Excessive Somnolence; Dose-Response Relationship, Drug; Female; Gene Frequency; Genotype; Humans; Male; Middle Aged; Multivariate Analysis; Polymerase Chain Reaction; Polymorphism, Genetic; RNA, Messenger; Threonine; Time Factors; Trans-Activators

2004
A trapping method for semi-quantitative assessment of reactive metabolite formation using [35S]cysteine and [14C]cyanide.
    Drug metabolism and pharmacokinetics, 2009, Volume: 24, Issue:3

    Topics: Biotransformation; Carbon Radioisotopes; Chromans; Clozapine; Cyclohexane Monoterpenes; Cysteine; Diclofenac; Humans; Microsomes, Liver; Monoterpenes; Pharmaceutical Preparations; Sodium Cyanide; Sulfur Radioisotopes; Technology, Pharmaceutical; Thiazolidinediones; Troglitazone

2009
Application of CYP102A1M11H as a tool for the generation of protein adducts of reactive drug metabolites.
    Chemical research in toxicology, 2011, Aug-15, Volume: 24, Issue:8

    Topics: Acetaminophen; Bacterial Proteins; Chromans; Chromatography, High Pressure Liquid; Clozapine; Cysteine; Cytochrome P-450 Enzyme System; Glutathione Transferase; Humans; Inactivation, Metabolic; Microsomes, Liver; NADPH-Ferrihemoprotein Reductase; Peptides; Protein Binding; Recombinant Fusion Proteins; Tandem Mass Spectrometry; Thiazolidinediones; Troglitazone; Trypsin

2011
A new quaternary ammonium cysteine analogue as a trapping reagent for reactive metabolites screening.
    Drug metabolism letters, 2014, Volume: 8, Issue:1

    Topics: Biotransformation; Chromatography, Liquid; Clozapine; Cysteine; Drug Discovery; Glutathione; High-Throughput Screening Assays; Humans; Microsomes, Liver; Tandem Mass Spectrometry; Trimethyl Ammonium Compounds

2014
Comparison of the Reactivity of Trapping Reagents toward Electrophiles: Cysteine Derivatives Can Be Bifunctional Trapping Reagents.
    Chemical research in toxicology, 2015, Aug-17, Volume: 28, Issue:8

    Topics: Chromatography, Liquid; Clozapine; Cross-Linking Reagents; Cysteine; Imidazoles; Mass Spectrometry; Molecular Structure; Pyridines; Sulfhydryl Compounds

2015