cysteine and bucillamine

cysteine has been researched along with bucillamine in 175 studies

Research

Studies (175)

Timeframe	Studies, this research(%)	All Research%
pre-1990	15 (8.57)	18.7374
1990's	56 (32.00)	18.2507
2000's	69 (39.43)	29.6817
2010's	32 (18.29)	24.3611
2020's	3 (1.71)	2.80

Authors

Authors	Studies
Funakoshi, T; Kiyozumi, M; Kojima, S; Shimada, H; Takahashi, Y	1
Goto, K; Nakahara, K; Tanaka, H	1
Fujinami, T; Koyama, K; Morozumi, K; Oikawa, T; Takeda, A; Yoshida, A	1
Ando, M; Araki, S; Hara, A; Iwakiri, T; Kohrogi, H; Matsumoto, M; Sakamoto, O; Sakata, T; Sugimoto, M	1
Arai, T; Fujigaki, Y; Hishida, A; Ikegaya, N; Isozaki, T; Kaneko, E; Kimura, M	1
Eguchi, K; Fukuda, T; Ida, H; Ishimaru, T; Kawakami, A; Nakashima, M; Sakai, M; Shimada, H; Terada, K; Yamashita, I	1
Fujimura, M; Kurashima, K; Matsuda, T; Nakao, S	1
Fukushima, T; Hashimoto, M; Ide, H; Kaga, S; Kasama, T; Kobayashi, K; Negishi, M; Tabata, M; Takahashi, T; Yamagata, N	1
Kiyozumi, M; Kojima, S; Tagawa, Y; Takahashi, Y	1
Fujinami, T; Ikeda, M; Koyama, K; Morozumi, K; Oikawa, T; Suganuma, T; Sugito, K; Takeda, A; Yoshida, A	1
Arimori, S; Ichikawa, Y; Shimizu, H	1
Amasaki, Y; Atsumi, T; Fujisaku, A; Jodo, S; Kobayashi, H; Mukai, M; Nakabayashi, T; Nakagawa, S; Sagawa, A; Watanabe, I	1
Hayashi, M; Matsunaga, K; Mita, S; Okahara, A	1
Yeung, JH	1
Baba, N; Nomura, T; Sakemi, T; Uchida, M; Watanabe, T	1
Aotsuka, S; Goto, M; Nakamura, K; Nishioka, K; Okamoto, M; Sasano, M; Yokohari, R	1
Endo, S; Furuya, R; Hishida, A; Itoh, M; Ogawa, N; Ohashi, H; Okugawa, T; Sudo, Y	1
Goto, M; Nishioka, K; Sasano, M	2
Iwainaka, Y; Kawano, M; Koni, I; Nakashima, A; Nomura, H; Takeda, R; Tofuku, Y	1
Matsunaga, K; Mita, S	1
Hayashi, M; Iso, T; Kasamatsu, S; Nakata, K; Sasano, M; Suda, H; Yamauchi, H	1
Hidano, A; Oryu, F; Yamaguchi, R	1
Ishikawa, K; Sakaguchi, M	1
Iso, T; Nakata, K; Suda, H; Yamauchi, H	1
Abe, C; Hayashi, M; Iso, T; Nozawa, RT; Shiokawa, Y; Yokota, T	1
Hayashi, M; Iso, T; Kasamatsu, S; Mibu, H; Nakata, K; Yamauchi, H	1
Abe, C	1
Fujimura, K; Hikida, M; Horiuchi, M; Iso, T; Kuwano, M; Morikawa, K; Uemura, O; Yamauchi, H	1
Horiuchi, M; Iso, T; Iwatani, T; Takashina, H	1
Horiuchi, M; Iso, T; Miyagi, S; Takashina, H; Uemura, O	1
Fujimura, H; Hiramatsu, Y; Iso, T; Koda, A; Nagai, H; Tamura, Y; Uda, K; Yamauchi, H; Yanagihara, M	1
Abe, T	2
Ohmori, H; Okimura, T; Yamamoto, I	1
Ishizaki, C; Kohsokabe, S; Nishida, H; Sueki, H	1
Brooks, P; Conaghan, PG	1
Funakoshi, T; Kojima, S; Shimada, H; Takahashi, Y	1
Ando, J; Hiramatsu, K; Inokuma, S; Matsuzaki, Y; Miyakuni, Y; Shiratori, K	1
Fujimura, M; Heki, U; Kitagawa, M; Matsuda, T; Ogawa, H	1
Brooks, P; Conaghan, PG; Girgis, L	1
Mochizuki, M; Sawa, K	1
Hirohata, S; Lipsky, PE	2
Hashimoto, M; Hiramatsu, K; Hosaka, M; Iwabuchi, H; Kaga, S; Kanemitsu, H; Kasama, T; Matsuda, A; Negishi, M; Yamazaki, J	1
Ichibangase, Y; Ohtsuka, E; Oribe, M; Sakai, K; Shiokawa, S; Takahashi, H; Wada, T; Yamamoto, M; Yasuda, M; Yoshioka, K	1
Kitano, T; Matsuno, H; Matsushita, I; Ochiai, H; Tsuji, H	1
Akamatsu, T; Matsubara, T; Mizuno, K; Saegusa, Y	1
Fukumoto, M; Okamoto, M; Suda, H	1
Ando, J; Inokuma, S; Ito, K; Kiyosawa, H; Kobayashi, S; Nozawa, F; Sakata, M	1
Hirohata, S; Inoue, T; Ito, K; Iwamoto, S; Kawashima, C; Kisaki, T; Nishioka, Y; Sawada, T; Shinohara, S; Tohma, S	1
In, H; Ito, S; Kikuchi, M; Nakano, M; Ozawa, T; Saeki, T; Saito, T; Sato, T; Suzuki, S; Ueno, M	1
Hashimoto, K; Lipsky, PE	1
Nobunaga, M; Yasuda, M	1
Hayakawa, M; Ikoma, T; Inokuma, S; Inoue, S; Negishi, M; Satou, T; Sayama, T; Shimizu, H; Ueda, A; Urano, Y	1
Inokuma, S; Kiyosawa, H; Sakata, M; Shiratori, K; Yoshida, A	1
Aono, H; Fujisawa, K; Hasunuma, T; Mita, S; Nakajima, T; Nishioka, K; Yamamoto, K	1
Hamada, M; Harada, K; Narazaki, R; Otagiri, M	1
Adachi, K; Aoki, T; Hara, J; Kitano, A; Kobayashi, K; Matsumoto, T; Nakamura, S; Obata, A; Obayashi, M; Okabe, H; Okawa, K; Oshitani, N; Suzuki, N; Tabata, A; Watanabe, Y; Yasuda, K	1
Asano, G; Koda, M; Nakamura, H; Yoshino, S	1
Arakawa, M; Hasegawa, H; Nakano, M; Nishi, S; Saito, T; Ueno, M	1
Furukawa, H; Hashimoto, S; Inoue, T; Ito, K; Sawada, T; Tohma, S	1
Kim, HA; Song, YW	1
Murakami, T; Sugita, T; Takata, I; Ueno, M	1
Hashimoto, H; Hirohata, S; Nakamura, H; Ochi, T; Tomita, T; Yanagida, T; Yoshino, S	1
Houki, N; Ichibangase, Y; Nobunaga, M; Yamamoto, M; Yasuda, M	1
Kawada, A; Kimura, M	1
Kubo, T; Matsuno, H; Matsuura, K; Muraguchi, A; Nezuka, T; Sugiyama, E; Tsuji, H	1
Aono, H; Kawashima, Y; Mita, S; Miyake, Y; Tsuji, F	1
Hara, S; Hideyuki, K; Mikami, A; Mori, T; Nakase, K; Sawa, N; Tachibana, S; Tagami, T; Takemoto, F; Ubara, Y; Yamada, A; Yokoyama, K	1
Arakawa, T; Kitano, A; Kuroki, T; Matsumoto, T; Nakamura, S; Oshitani, N	1
Kumagai, S; Morinobu, A; Wang, Z	1
Aono, H; Horiuchi, M; Matsuoka, H; Mita, S; Nishimura, K; Takai, M; Tsuji, F	1
Hirata, D; Iwamoto, M; Kamimura, T; Kano, S; Masuyama, JI; Mimori, A; Minota, S; Okazaki, H; Sato, H; Yoshio, T	1
Isome, M; Kawasaki, Y; Nozawa, R; Sike, T; Suyama, K; Suzuki, H; Suzuki, J; Suzuki, S	1
Dobers, J; Ishii, T; Iwata, S; Morimoto, C; Munakata, Y; Nori, M; Tanaka, H	1
Hefferton, D; Rahman, P; Robb, D	1
Asano, G; Nagashima, M; Yoshino, S	1
Aono, H; Hirano, D; Ishigami, S; Nagashima, M; Sasano, M; Takai, M; Wauke, K; Yoshino, S	1
Sule, SD; Wigley, FM	1
Amagai, M; Hashimoto, T; Ikeda, M; Kodama, H; Nakajima, H; Ogata, K; Yamamoto, Y	1
Kanazawa, M; Kawabata, Y; Matsushima, H; Motegi, M; Sakamoto, T; Sugita, Y; Takayanagi, N; Ubukata, M; Yanagisawa, T	1
Fukushima, K; Inoue, T; Takeshita, K	1
Ji, JD; Kang, KH; Kim, HK; Kim, YR; Lee, JH; Lee, YH; Shim, JJ; Song, GG	1
Horwitz, LD; Sherman, NA	1
Brechun, N; Diaz-Sanchez, D; Horwitz, LD; Horwitz, MA; Li, N; Nel, AE; Nelson, SK; Wang, M; Whitekus, MJ; Zhang, M	1
Hara, M; Hara, S; Matsushita, H; Nagahama, K; Ubara, Y; Yamada, A	1
Hanaoka, R; Hanyuda, M; Ide, H; Kaga, S; Kasama, T; Miwa, Y; Negishi, M; Shiozawa, F	1
Amersi, F; Busuttil, RW; Horwitz, LD; Horwitz, MA; Kato, H; Kupiec-Weglinski, JW; Melinek, J; Nelson, SK; Shen, XD	1
Fujii, K; Kishimoto, N	1
Kumagai, N; Ono, K; Sakai, Y; Wakamatsu, S	1
Hikichi, T; Horikawa, Y; Matsuoka, H; Mori, F; Nakamura, M; Sasaki, M; Shishido, N; Takamiya, A; Takeda, M; Yoshida, A	1
Homma, N; Mano, H; Matsuoka, H; Muranaka, K; Obata, R; Tamaki, Y; Yanagi, Y	1
Honda, Y; Koyama, S; Nishimura, K; Oh, H; Otani, A; Takagi, H	1
Hikichi, T; Horikawa, Y; Mori, F; Nakamura, M; Sasaki, M; Shishido, N; Yoshida, A	1
Inoue, T; Nakaike, S; Sugimoto, M; Takeshita, K; Yamashita, M	1
Horwitz, LD	1
Harada, T; Obayashi, M; Takahara, K; Uzu, T; Yamato, M; Yamauchi, A	1
del Rosso, A; Distler, JH; Distler, O; Gay, RE; Gay, S; Hagen, C; Hirth, A; Kalden, JR; Lorenz, HM; Matucci-Cerinic, M; Michel, BA; Müller-Ladner, U; Nanagara, R; Nishioka, K	1
Hirohata, S; Isshi, K; Kikuchi, H	1
Beaudry, F; Furtado, M; Proulx, D	1
Urata, Y	1
Ohno, I	1
Hashimoto, S; Iwata, M; Nagai, C; Shimizu, Y; Takeda, T; Takeuchi, M; Uchiyama, S	1
Gomita, Y; Kawasaki, Y; Moriyama, M; Shibata, K	1
Kawabata, D; Mimori, T	1
Aboul-Enein, HY; Bunaciu, AA; Fleschin, S	1
Aoyama, M; Asai, K; Fukuoka, M; Kobayashi, M; Kusabe, T; Otsuka, T; Tanikawa, T; Waguri-Nagaya, Y	1
Asada, H; Izumi, A; Katsumi, S; Kobayashi, N; Miyagawa, S; Niizeki, H	1
Matsuhashi, M; Sagawa, A; Shimizu, M; Shinohara, M; Tanimura, K	1
Amano, K; Kameda, H; Sekiguchi, N; Takeuchi, T	1
Hara, S; Hoshino, J; Katori, H; Sawa, N; Suwabe, T; Tagami, T; Takaichi, K; Takemoto, F; Ubara, Y	1
Hur, JW; Lee, CW; Yoo, DH	1
Chianale, J; Farias, M; Vollrath, V; Wielandt, AM	1
Hokonohara, D; Kajiya, T; Kuroda, A; Tei, C	1
Greenberg, L; Mazor, D; Meyerstein, D; Meyerstein, N; Shamir, D	1
Yamamoto, T; Yokozeki, H	1
Berezné, A; Guillevin, L; Mouthon, L; Poiraudeau, S	1
Hara, M; Inoue, E; Iwatani, M; Kamatani, N; Nakajima, A; Nakamura, T; Tomatsu, T; Yamanaka, H	1
Nakamura, K; Nakashima, T; Ochi, S; Oda, H; Suematsu, A; Tajiri, Y; Taka, J; Takayanagi, H; Tanaka, S	1
Itou, K; Kanazawa, T; Kuga, Y; Morishita, M; Tanida, K; Yokota, N	1
Matsuda, T; Ohtsubo, H	1
Abe, S; Azuma, A; Fukuda, Y; Kudoh, S; Nakayama, T; Nei, T; Saito, Y; Usuki, J	1
Fukushima, K; Gono, T; Ikeda, S; Katoh, N; Matsuda, M; Mitsuhashi, S; Takei, Y	1
Saito, E; Suwa, A; Suzuki, Y; Wakabayashi, T	1
Akizawa, T; Koshikawa, S; Kuroki, A	1
Fujimura, M; Kasahara, K; Nakao, S; Nakatsumi, Y; Tambo, Y; Yasui, M	1
Makino, F; Mochizuki, H; Morioka, T; Ogiwara, Y; Sugihara, T; Takahashi, H	1
Ideguchi, H; Ishigatsubo, Y; Nagaoka, S; Ohono, S; Soga, T; Suda, A	1
Ambler, SK; Hodges, YK; Horwitz, LD; Jones, GM; Long, CS	1
Hagihara, M; Hayashi, K; Miyasaka, N; Ogasawara, H; Tohda, S; Toi, H; Tojo, N	1
Arimitsu, J; Hagihara, K; Hirano, T; Kawai, M; Kawase, I; Kuwahara, Y; Nakanishi, K; Narazaki, M; Ogata, A; Shima, Y; Tanaka, T; Terabe, F	1
Hirohata, S; Tomita, T; Yanagida, T; Yoshikawa, H	1
Yamanaka, H	1
Mimori, T; Yukawa, N	1
Aono, H; Kageyama, M; Ohashi, K; Oki, K; Sasano, M; Tsuji, F	1
Abe, M; Kinoshita, M; Nakajima, M; Ohara, H; Ueda, N	1
Chun, YG; Kim, I; Lee, KC; Park, ES; Shin, BS; Yoo, SD; Youn, YS	1
Iwatani, M; Kobashigawa, T; Kotake, S; Nanke, Y; Yago, T; Yamanaka, H	1
Cacciatore, I; Cornacchia, C; Feliciani, F; Mollica, A; Pinnen, F; Stefanucci, A; Torino, D	1
Aono, H; Katsuta, O; Okamoto, M; Setoguchi, C; Tsuji, F	1
Komase, Y; Sakaida, H; Takemura, T	1
Davidson, BR; Dijk, S; Fuller, B; Junnarkar, SP; Mani, A; Seifalian, AM; Tapuria, N	1
Amasaki, Y; Fujisaku, A; Ichikawa, K; Mukai, M; Ohnishi, K; Ohsaki, H; Sagawa, A; Shimizu, M; Yasuda, I	1
Kawai, S; Miyasaka, N; Takeuchi, T; Tanaka, Y; Yamamoto, K	1
Koyama, Y; Ohta, T; Shiraishi, H; Uchino, A	1
Amano, H; Kageyama, M; Kempe, K; Kusaoi, M; Matsudaira, R; Matsushita, M; Morimoto, S; Nawata, M; Ogasawara, M; Onuma, S; Sekiya, F; Tada, K; Takasaki, Y; Tamura, N; Toyama, S; Yamaji, K	1
Baňasová, M; Hrabárová, E; Juránek, I; Nagy, M; Priesolová, E; Soltés, L; Valachová, K	1
Fujimura, A; Fujiwara, Y; Koshimizu, TA; Sakai, N; Shibata, K; Tsuchiya, H	1
Hirotoshi, K; Ikeda, K; Kawashima, H; Kobayashi, Y; Nakagomi, D; Nakajima, H; Suto, A	1
Ito, S	2
Ichikawa, N; Yamanaka, H	1
Kageyama, M; Kempe, K; Kon, T; Kusaoi, M; Matsudaira, R; Matsushita, M; Ogasawara, M; Onuma, S; Sekiya, F; Sugimoto, K; Tada, K; Takasaki, Y; Tamura, N; Yamaji, K	1
Aono, H; Okamoto, M; Sasano, M; Seki, I; Setoguchi, C; Tsuji, F	1
Suzuki, Y	1
Tamura, N	1
Banasova, M; Juranek, I; Mendichi, R; Perecko, T; Sasinkova, V; Soltes, L; Valachova, K	1
Mitani, Y	1
Tanaka, E; Yamanaka, H	1
Amano, K; Kameda, H; Kishimoto, M; Kurasawa, T; Nagasawa, H; Takeuchi, T	1
Boudier, A; Dahboul, F; Lartaud, I; Leroy, P; Perrin-Sarrado, C; Schneider, R	1
Tamada, Y; Watanabe, D; Yanagishita, T	1
Choe, SK; Ho Hur, J; Kim, HJ; Kim, SJ; Lee, JN; Lim, DJ; Moon, SK; Oh, GS; Park, C; Park, R; So, HS; Yoo, SJ	1
Abe, C; Funahashi, K; Katayama, K; Kondo, M; Matsubara, T; Matsuno, H; Okada, M; Sagawa, A; Sakai, Y; Yamasaki, K	1
Bujdák, J; Šoltés, L; Topolská, D; Valachová, K; Valent, I	1
Keenan, RT; Schlesinger, N	1
Hase, I; Ishii, Y; Kurasawa, K; Sakuma, H; Takizawa, H; Yamaguchi, B	1
Fukada, A; Nozue, T; Suda, T; Toyoshima, M	2
Kalemci, S; Sarıhan, A; Şimşek, A; Zeybek, A	1
Higuchi, R; Mori, T; Shimada, K; Sugii, S; Tsujino, M; Yokogawa, N	1
Aryanian, Z; Daneshpazhooh, M; Etesami, I; Ghaedi, F; Goodarzi, A; Kalantari, Y; Mahmoudi, H; Tavakolpour, S; Teymourpour, A	1
Frank, M	1

Reviews

28 review(s) available for cysteine and bucillamine

Article	Year
Bucillamine (a new therapeutic agent for rheumatoid arthritis) induced nephrotic syndrome: a report of two cases and review of the literature. The Clinical investigator, 1992, Volume: 70, Issue:11 Topics: Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Cysteine; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Nephrotic Syndrome; Structure-Activity Relationship; Sulfhydryl Compounds	1992
"Yellow nail syndrome" and rheumatoid arthritis. The Tokai journal of experimental and clinical medicine, 1991, Volume: 16, Issue:5-6 Topics: Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Cysteine; Female; Humans; Male; Middle Aged; Nail Diseases; Nails; Penicillamine; Syndrome	1991
[Drug therapy of vasculitis with immunosuppressive agents, immunomodulators and cyclosporin A]. Nihon rinsho. Japanese journal of clinical medicine, 1985, Volume: 43, Issue:10 Topics: Adjuvants, Immunologic; Animals; Azathioprine; Chromones; Cyclophosphamide; Cyclosporins; Cysteine; Humans; Immunosuppressive Agents; ortho-Aminobenzoates; Vasculitis	1985
[Development and clinical use of chemical immunomodulators]. Nihon rinsho. Japanese journal of clinical medicine, 1981, Volume: 39, Issue:4 Topics: Adjuvants, Immunologic; Animals; Anti-Inflammatory Agents; Antibody Formation; Arthritis, Experimental; Auranofin; Aurothioglucose; Collagen Diseases; Cysteine; Guinea Pigs; Humans; Levamisole; Male; ortho-Aminobenzoates; Rats	1981
Disease-modifying antirheumatic drugs, including methotrexate, gold, antimalarials, and D-penicillamine. Current opinion in rheumatology, 1995, Volume: 7, Issue:3 Topics: Anti-Inflammatory Agents, Non-Steroidal; Antimalarials; Antirheumatic Agents; Arthritis, Rheumatoid; Clinical Trials as Topic; Cysteine; Drug Therapy, Combination; Gold; Humans; Methotrexate; Penicillamine; Sulfasalazine	1995
Disease-modifying antirheumatic drugs, including methotrexate, sulfasalazine, gold, antimalarials, and penicillamine. Current opinion in rheumatology, 1994, Volume: 6, Issue:3 Topics: Age Factors; Antimalarials; Arthritis, Rheumatoid; Clinical Trials as Topic; Cysteine; Digestive System; Gold; Humans; Liver; Methotrexate; Penicillamine; Sulfasalazine	1994
[Drug-induced renal disorders in patients with rheumatoid arthritis]. Ryumachi. [Rheumatism], 1996, Volume: 36, Issue:5 Topics: Anti-Inflammatory Agents, Non-Steroidal; Antirheumatic Agents; Arthritis, Rheumatoid; Cyclosporine; Cysteine; Humans; Kidney Diseases; Methotrexate; ortho-Aminobenzoates	1996
Novel therapy in the treatment of scleroderma. Expert opinion on investigational drugs, 2001, Volume: 10, Issue:1 Topics: Autoimmune Diseases; Bone Marrow Transplantation; Cysteine; Humans; Interferon-gamma; Nitric Oxide; Piperidines; Prostaglandins; Quinazolines; Quinazolinones; Relaxin; Scleroderma, Systemic; Tetracycline; Transforming Growth Factor beta; Tumor Necrosis Factor-alpha	2001
[A case of pulmonary infiltration with eosinophilia (PIE) syndrome induced by bucillamine treatment of rheumatoid arthritis]. Nihon Kokyuki Gakkai zasshi = the journal of the Japanese Respiratory Society, 2002, Volume: 40, Issue:4 Topics: Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Cysteine; Drug Eruptions; Female; Humans; Lung; Middle Aged; Pulmonary Eosinophilia	2002
Bucillamine: a potent thiol donor with multiple clinical applications. Cardiovascular drug reviews, 2003,Summer, Volume: 21, Issue:2 Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Cardiac Surgical Procedures; Clinical Trials as Topic; Cysteine; Disease Models, Animal; Drug Evaluation, Preclinical; Humans; Ischemia; Liver; Liver Transplantation; Myocardial Infarction; Oxidative Stress; Reperfusion Injury	2003
[Drug induced nephrotic syndrome]. Nihon rinsho. Japanese journal of clinical medicine, 2004, Volume: 62, Issue:10 Topics: Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents; Antirheumatic Agents; Cysteine; Humans; Nephrotic Syndrome; Organogold Compounds; Penicillamine	2004
[Bucillamine-induced dermatomyositis-like clinical features in a patient with rheumatoid arthritis]. Rinsho shinkeigaku = Clinical neurology, 2005, Volume: 45, Issue:1 Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Cysteine; Dermatomyositis; Female; Humans	2005
[Disease modifying anti-rheumatic drugs (DMARDs): an overview]. Nihon rinsho. Japanese journal of clinical medicine, 2005, Volume: 63 Suppl 1 Topics: Antirheumatic Agents; Arthritis, Rheumatoid; Benzopyrans; Cysteine; Evidence-Based Medicine; Gold Sodium Thiomalate; Humans; Isoxazoles; Leflunomide; Meta-Analysis as Topic; Methotrexate; Randomized Controlled Trials as Topic; Sulfasalazine; Sulfonamides	2005
Bucillamine-induced toxic epidermal necrolysis and fixed drug eruption. The Journal of dermatology, 2005, Volume: 32, Issue:5 Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Biopsy, Needle; Cysteine; Drug Eruptions; Female; Follow-Up Studies; Humans; Immunohistochemistry; Long-Term Care; Middle Aged; Risk Assessment; Severity of Illness Index; Stevens-Johnson Syndrome	2005
[Therapeutic management of systemic sclerosis]. Presse medicale (Paris, France : 1983), 2006, Volume: 35, Issue:12 Pt 2 Topics: Acute Kidney Injury; Angiotensin-Converting Enzyme Inhibitors; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Antihypertensive Agents; Cyclophosphamide; Cysteine; Epoprostenol; Humans; Hypertension, Pulmonary; Immunosuppressive Agents; Interferons; Lung Diseases, Interstitial; Orthotic Devices; Penicillamine; Peripheral Blood Stem Cell Transplantation; Physical Therapy Modalities; Prospective Studies; Randomized Controlled Trials as Topic; Retrospective Studies; Scleroderma, Systemic; Vasodilator Agents	2006
[Effective combination therapy of TNF antagonists with DMARDs]. Nihon rinsho. Japanese journal of clinical medicine, 2007, Volume: 65, Issue:7 Topics: Adalimumab; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antirheumatic Agents; Arthritis, Rheumatoid; Azathioprine; Cysteine; Drug Therapy, Combination; Etanercept; Humans; Hydroxychloroquine; Immunoglobulin G; Infliximab; Isoxazoles; Leflunomide; Methotrexate; Receptors, Tumor Necrosis Factor; Sulfasalazine; Tumor Necrosis Factor-alpha	2007
[Adverse effects of conventional DMARDs and biologic DMARDs]. Nihon rinsho. Japanese journal of clinical medicine, 2007, Oct-28, Volume: 65 Suppl 8 Topics: Antibodies, Monoclonal; Antirheumatic Agents; Chemical and Drug Induced Liver Injury; Cysteine; Drug Eruptions; Drug Hypersensitivity; Hematologic Diseases; Humans; Immune System Diseases; Infliximab; Isoxazoles; Kidney Diseases; Leflunomide; Lung Diseases; Methotrexate	2007
[Drug-induced nephrotic syndrome]. Nihon rinsho. Japanese journal of clinical medicine, 2007, Oct-28, Volume: 65 Suppl 8 Topics: Anti-Inflammatory Agents, Non-Steroidal; Antidepressive Agents; Antineoplastic Agents; Antirheumatic Agents; Bone Density Conservation Agents; Cysteine; Diphosphonates; Gold Compounds; Humans; Interferons; Lithium Compounds; Nephrotic Syndrome; Pamidronate; Penicillamine	2007
A case with life-threatening interstitial pneumonia associated with bucillamine treatment. Modern rheumatology, 2008, Volume: 18, Issue:5 Topics: Aged, 80 and over; Antioxidants; Arthritis, Rheumatoid; Cysteine; Female; Humans; Lung Diseases, Interstitial	2008
[Antirheumatic agents for treatment of rheumatoid arthritis]. Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine, 2008, Oct-10, Volume: 97, Issue:10 Topics: Antirheumatic Agents; Arthritis, Rheumatoid; Cysteine; Gold Sodium Thiomalate; Humans; Isoxazoles; Leflunomide; Methotrexate; Pharmacogenetics; Randomized Controlled Trials as Topic; Remission Induction; Sulfasalazine; Time Factors	2008
[Effect of disease modifying anti-rheumatic drugs on radiographic progression in rheumatoid arthritis]. Clinical calcium, 2009, Volume: 19, Issue:3 Topics: Antirheumatic Agents; Arthritis, Rheumatoid; Cyclosporine; Cysteine; Disease Progression; Drug Therapy, Combination; Gold Sodium Thiomalate; Humans; Isoxazoles; Leflunomide; Methotrexate; Penicillamine; Radiography; Randomized Controlled Trials as Topic; Sulfasalazine; Tacrolimus	2009
Bucillamine-induced yellow nail in Japanese patients with rheumatoid arthritis: two case reports and a review of 36 reported cases. Rheumatology international, 2013, Volume: 33, Issue:3 Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Cysteine; Female; Humans; Male; Yellow Nail Syndrome	2013
[Treatment of rheumatic diseases: current status and future prospective. Topics: II. Immunosuppressant/antirheumatic drugs; 6. Bucillamine and gold (gold sodium thiomalate and auranofin)]. Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine, 2011, Oct-10, Volume: 100, Issue:10 Topics: Anti-Inflammatory Agents, Non-Steroidal; Antirheumatic Agents; Arthritis, Rheumatoid; Auranofin; Cysteine; Gold Sodium Thiomalate	2011
[ Bone and cartilage destruction in RA and its intervention. Disease-modifying antirheumatic drugs]. Clinical calcium, 2012, Volume: 22, Issue:2 Topics: Antirheumatic Agents; Arthritis, Rheumatoid; Bone and Bones; Cartilage; Clinical Trials as Topic; Cysteine; Humans; Isoxazoles; Joints; Leflunomide; Methotrexate; Sulfasalazine; Tacrolimus	2012
[DMARDs (disease-modifying antirheumatic drugs)]. Nihon rinsho. Japanese journal of clinical medicine, 2013, Volume: 71, Issue:7 Topics: Antirheumatic Agents; Arthritis, Rheumatoid; Cysteine; Humans; Japan; Methotrexate; Sulfasalazine; Tacrolimus	2013
New and Pipeline Drugs for Gout. Current rheumatology reports, 2016, Volume: 18, Issue:6 Topics: Anti-Inflammatory Agents; Biological Products; Cysteine; Drug Discovery; Gout; Gout Suppressants; Humans; Interleukin-1beta; Thioglycolates; Triazoles	2016
[DMARDs (Focusing on iguratimod)]. Nihon rinsho. Japanese journal of clinical medicine, 2016, Volume: 74, Issue:6 Topics: Antirheumatic Agents; Arthritis, Rheumatoid; Chromones; Cysteine; Drug Discovery; Drug Interactions; Drug Substitution; Drug Therapy, Combination; Drugs, Generic; Female; Humans; Male; Ribonucleosides; Sulfasalazine; Sulfonamides; Tacrolimus	2016
Drug-induced pemphigus: A systematic review of 170 patients. International immunopharmacology, 2021, Volume: 92 Topics: Anti-Inflammatory Agents, Non-Steroidal; Antihypertensive Agents; Antirheumatic Agents; Captopril; Cysteine; Drug-Related Side Effects and Adverse Reactions; Humans; Pemphigus; Penicillamine	2021

Trials

10 trial(s) available for cysteine and bucillamine

Article	Year
SA 96 (N-(2-mercapto-2-methylpropanoyl)-L-cysteine) in rheumatoid arthritis. Scandinavian journal of rheumatology, 1986, Volume: 15, Issue:1 Topics: Adult; Aged; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Chemical and Drug Induced Liver Injury; Clinical Trials as Topic; Cysteine; Drug Eruptions; Elasticity; Female; Gold; Humans; Middle Aged; Penicillamine; Tensile Strength; Time Factors	1986
Efficacy of additive DMARD therapy in patients with rheumatoid arthritis. Double blind controlled trial using bucillamine and placebo with maintenance doses of gold sodium thiomalate. The Journal of rheumatology, 1994, Volume: 21, Issue:1 Topics: Aged; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Child, Preschool; Cysteine; Double-Blind Method; Drug Combinations; Female; Gold Sodium Thiomalate; Humans; Life Tables; Male; Middle Aged; Placebos; Prospective Studies; Time Factors; Treatment Outcome	1994
Comparison of clinical effects of bucillamine between additive combination and single administration study in rheumatoid arthritis. Agents and actions. Supplements, 1993, Volume: 44 Topics: Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Cysteine; Double-Blind Method; Drug Therapy, Combination; Humans	1993
A comparison between bucillamine and D-penicillamine in the treatment of rheumatoid arthritis. Rheumatology international, 1997, Volume: 17, Issue:1 Topics: Adolescent; Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Antirheumatic Agents; Arthritis, Rheumatoid; Cysteine; Female; Humans; Male; Middle Aged; Penicillamine	1997
Clinical course of bucillamine-induced nephropathy in patients with rheumatoid arthritis. Clinical and experimental nephrology, 2003, Volume: 7, Issue:4 Topics: Adult; Aged; Antirheumatic Agents; Arthritis, Rheumatoid; Cysteine; Disease Progression; Dose-Response Relationship, Drug; Female; Glomerulonephritis, Membranous; Humans; Kidney; Kidney Function Tests; Male; Middle Aged; Proteinuria	2003
Efficacy profile of bucillamine in rheumatoid arthritis patients in a large observational cohort study, IORRA. Modern rheumatology, 2006, Volume: 16, Issue:6 Topics: Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Cohort Studies; Cysteine; Drug Therapy, Combination; Female; Health Status; Humans; Joints; Male; Methotrexate; Middle Aged; Pain; Prednisolone; Prospective Studies; Remission Induction; Severity of Illness Index; Sulfasalazine	2006
A comparative study of the effects of bucillamine and salazosulfapyridine in the treatment of rheumatoid arthritis. Modern rheumatology, 2009, Volume: 19, Issue:4 Topics: Antirheumatic Agents; Arthritis, Rheumatoid; C-Reactive Protein; Cysteine; Drug Therapy, Combination; Female; Hand Strength; Health Status; Humans; Joints; Male; Middle Aged; Pain; Prednisolone; Severity of Illness Index; Sulfasalazine; Time Factors; Treatment Outcome	2009
A multicentre trial of bucillamine in the treatment of early rheumatoid arthritis (SNOW study). Modern rheumatology, 2011, Volume: 21, Issue:3 Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Antirheumatic Agents; Arthritis, Rheumatoid; Child; Cysteine; Early Diagnosis; Female; Humans; Male; Methotrexate; Middle Aged; Patient Dropouts; Remission Induction; Treatment Outcome; Young Adult	2011
Efficacy and safety of additional use of tacrolimus in patients with early rheumatoid arthritis with inadequate response to DMARDs--a multicenter, double-blind, parallel-group trial. Modern rheumatology, 2011, Volume: 21, Issue:5 Topics: Adult; Antirheumatic Agents; Arthritis, Rheumatoid; Cysteine; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Immunosuppressive Agents; Joints; Male; Methotrexate; Middle Aged; Severity of Illness Index; Sulfasalazine; Tacrolimus; Treatment Outcome	2011
Addition of another disease-modifying anti-rheumatic drug to methotrexate reduces the flare rate within 2 years after infliximab discontinuation in patients with rheumatoid arthritis: an open, randomized, controlled trial. Modern rheumatology, 2014, Volume: 24, Issue:4 Topics: Adult; Aged; Antibodies, Monoclonal; Antirheumatic Agents; Arthritis, Rheumatoid; Cysteine; Disease Progression; Drug Therapy, Combination; Female; Humans; Infliximab; Male; Methotrexate; Middle Aged; Treatment Outcome; Young Adult	2014

Other Studies

137 other study(ies) available for cysteine and bucillamine

Article	Year
Characterization of gold in urine and bile following administration of gold sodium thiomalate with chelating agents to rats. Toxicology, 1992, Volume: 74, Issue:1 Topics: Animals; Bile; Chelating Agents; Chromatography; Cysteine; Electrophoresis; Gold; Gold Sodium Thiomalate; Injections, Intravenous; Male; Penicillamine; Rats; Rats, Inbred Strains; Succimer; Unithiol	1992
[A case of bucillamine-induced pneumonitis]. Nihon Kyobu Shikkan Gakkai zasshi, 1992, Volume: 30, Issue:4 Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Bronchoalveolar Lavage Fluid; Cysteine; Female; Gold Sodium Thiomalate; Lung; Pneumonia	1992
A case of rapidly progressive glomerulonephritis associated with bucillamine-treated rheumatoid arthritis. American journal of kidney diseases : the official journal of the National Kidney Foundation, 1992, Volume: 20, Issue:4 Topics: Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Biopsy; Cysteine; Female; Glomerulonephritis; Humans; Kidney; Microscopy, Electron; Middle Aged; Time Factors	1992
[A case of bucillamine-induced interstitial pneumonia]. Nihon Kyobu Shikkan Gakkai zasshi, 1992, Volume: 30, Issue:9 Topics: Anti-Inflammatory Agents, Non-Steroidal; Arthritis; Cysteine; Humans; Male; Middle Aged; Patch Tests; Pulmonary Fibrosis	1992
Bucillamine inhibits T cell adhesion to human endothelial cells. The Journal of rheumatology, 1992, Volume: 19, Issue:7 Topics: Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Catalase; Cell Adhesion; Cell Communication; Cells, Cultured; Copper; Copper Sulfate; Cysteine; Endothelium, Vascular; Humans; Hydrogen Peroxide; Interferon-gamma; Recombinant Proteins; Superoxide Dismutase; T-Lymphocytes; Umbilical Veins	1992
Bucillamine-induced hypersensitivity pneumonitis. Chest, 1992, Volume: 101, Issue:5 Topics: Alveolitis, Extrinsic Allergic; Anti-Inflammatory Agents, Non-Steroidal; Bronchoalveolar Lavage Fluid; Cysteine; Female; Humans; Middle Aged	1992
[Lung injury associated with bucillamine therapy]. Ryumachi. [Rheumatism], 1992, Volume: 32, Issue:2 Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Cysteine; Female; Humans; Male; Middle Aged; Pulmonary Fibrosis	1992
Protective effects of chelating agents against renal toxicity of gold sodium thiomalate in rats. Archives of toxicology, 1991, Volume: 65, Issue:7 Topics: Animals; Chelating Agents; Cysteine; Glycosuria; Gold Sodium Thiomalate; Kidney Diseases; Male; Penicillamine; Rats; Rats, Inbred Strains; Succimer; Unithiol	1991
Clinicopathological findings of bucillamine-induced nephrotic syndrome in patients with rheumatoid arthritis. American journal of nephrology, 1991, Volume: 11, Issue:4 Topics: Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Biopsy; Cysteine; Female; Fluorescent Antibody Technique; Glomerulonephritis, Membranous; Humans; Kidney; Male; Microscopy, Electron; Middle Aged; Nephrotic Syndrome	1991
[A case of rheumatoid arthritis developing pemphigus-like skin lesion during treatment with bucillamine]. Ryumachi. [Rheumatism], 1991, Volume: 31, Issue:5 Topics: Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Cysteine; Drug Eruptions; Female; Humans; Middle Aged; Pemphigus	1991
Effect of bucillamine (SA96) on type II collagen induced arthritis in rats. The Journal of rheumatology, 1991, Volume: 18, Issue:5 Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Experimental; Cell Division; Collagen; Cysteine; Dose-Response Relationship, Drug; Indomethacin; Male; Penicillamine; Rats; Synovial Membrane	1991
The effects of bucillamine on glutathione and glutathione-related enzymes in the mouse. Biochemical pharmacology, 1991, Jul-25, Volume: 42, Issue:4 Topics: Alanine Transaminase; Animals; Cysteine; Glutathione; Glutathione Disulfide; Glutathione Peroxidase; Glutathione Reductase; Glutathione Transferase; Liver; Male; Mice; Mice, Inbred Strains; Oxidation-Reduction	1991
[Membranous glomerulonephritis probably related to bucillamine therapy in two patients with rheumatoid arthritis]. Nihon Jinzo Gakkai shi, 1991, Volume: 33, Issue:6 Topics: Anti-Inflammatory Agents; Arthritis, Rheumatoid; Complement C3; Cysteine; Female; Glomerulonephritis, Membranous; Humans; Immunoglobulin G; Kidney; Male; Middle Aged	1991
Suppressive effect of anti-rheumatic drugs on interleukin-1 beta release from human peripheral blood monocytes. International journal of immunopharmacology, 1991, Volume: 13, Issue:1 Topics: Anti-Inflammatory Agents, Non-Steroidal; Auranofin; Cysteine; Enzyme-Linked Immunosorbent Assay; Humans; Ibuprofen; Immunosuppressive Agents; In Vitro Techniques; Interleukin-1; Monocytes	1991
[A case of progressive systemic sclerosis with Sjögren's syndrome complicated by nephrotic syndrome caused by bucillamine]. Ryumachi. [Rheumatism], 1990, Volume: 30, Issue:5 Topics: Anti-Inflammatory Agents, Non-Steroidal; Cysteine; Female; Humans; Middle Aged; Nephrotic Syndrome; Scleroderma, Systemic; Sjogren's Syndrome	1990
Modulatory effect of bucillamine (SA96) on interleukin-1-and/or -2-induced proliferation of T lymphocytes. Agents and actions, 1990, Volume: 31, Issue:3-4 Topics: Anti-Inflammatory Agents, Non-Steroidal; Cell Division; Cysteine; Humans; Interleukin-1; Interleukin-2; Phytohemagglutinins; T-Lymphocytes	1990
[Bucillamine-associated membranous nephropathy in a patient with rheumatoid arthritis]. Nihon Jinzo Gakkai shi, 1990, Volume: 32, Issue:7 Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Cysteine; Female; Glomerulonephritis, Membranous; Humans	1990
Differences in the effects of the antirheumatic drugs, bucillamine and D-penicillamine, on mitogen-induced proliferation of mouse spleen cells. Agents and actions, 1990, Volume: 30, Issue:3-4 Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Catalase; Cell Division; Cells, Cultured; Concanavalin A; Copper; Cysteine; Male; Mice; Mice, Inbred C3H; Penicillamine; Spleen; Structure-Activity Relationship	1990
[Pharmacological studies on N-(2-mercapto-2-methylpropanoyl)-L-cysteine(SA96). IV. Effects of SA96 and its main metabolite, SA679, on denaturation of human gamma-globulin and adjuvant arthritis in rats]. Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1985, Volume: 85, Issue:4 Topics: Animals; Anti-Inflammatory Agents; Arthritis; Arthritis, Experimental; Cysteine; gamma-Globulins; Indomethacin; Male; Organ Size; Penicillamine; Protein Denaturation; Rats; Rats, Inbred Lew; Serum Albumin, Bovine	1985
Decrease in disease activity and concomitant increase in the percentage of peripheral blood suppressor T-cells in rheumatoid arthritis by a newly synthesized slow-acting anti-rheumatic drug (Bucillamine). International journal of immunopharmacology, 1989, Volume: 11, Issue:4 Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Cysteine; Female; Flow Cytometry; Fluorescent Antibody Technique; Humans; Immunoglobulin G; Leukocyte Count; Middle Aged; T-Lymphocytes, Regulatory; Time Factors	1989
A case of bullous pemphigoid induced by tiobutarit (D-penicillamine analogue). The Journal of dermatology, 1989, Volume: 16, Issue:4 Topics: Anti-Inflammatory Agents; Arthritis, Rheumatoid; Cysteine; Female; Humans; Middle Aged; Pemphigoid, Bullous; Skin Diseases, Vesiculobullous	1989
Pharmacological studies of N-(2-mercapto-2-methylpropanoyl)-L-cysteine (SA96) (3). Effects of SA96 on experimental allergic reactions. Japanese journal of pharmacology, 1985, Volume: 37, Issue:1 Topics: Anaphylaxis; Animals; Anti-Inflammatory Agents; Arthus Reaction; Cell Migration Inhibition; Complement Activation; Cysteine; Guinea Pigs; Hemolysis; Hypersensitivity; Hypersensitivity, Delayed; Immunoglobulin E; Macrophages; Male; Passive Cutaneous Anaphylaxis; Rats; Rats, Inbred Strains	1985
Effects of immunomodulators on candidacidal activity of normal peritoneal cells in BALB/c mice. International journal of immunopharmacology, 1986, Volume: 8, Issue:3 Topics: Animals; Anti-Inflammatory Agents; Candidiasis; Cysteine; Female; Hydrocortisone; Levamisole; Lipopolysaccharides; Macrophages; Mice; Mice, Inbred BALB C; Penicillamine	1986
[Pharmacological studies of N-(2-mercapto-2-methylpropanoyl)-L-cysteine (SA96). V. Effects of SA96 in combination with indomethacin or prednisolone on adjuvant arthritis in rats]. Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1985, Volume: 85, Issue:4 Topics: Animals; Anti-Inflammatory Agents; Arthritis; Arthritis, Experimental; Blood Proteins; Blood Sedimentation; Copper; Cysteine; Drug Therapy, Combination; Edema; Indomethacin; Male; Prednisolone; Rats; Rats, Inbred Lew	1985
[Pharmacological studies of N-(2-mercapto-2-methylpropionyl)-L-cysteine (SA 96). VI. Effects on vitamin B6, metals and skin collagen in rats]. Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1985, Volume: 86, Issue:1 Topics: Animals; Anti-Inflammatory Agents; Body Weight; Collagen; Cysteine; Liver; Male; Metals; Penicillamine; Pyridoxine; Rats; Rats, Inbred Strains; Skin	1985
[Study on metabolism of the dithiol compound. I. Isolation and identification of metabolites of N-(2-mercapto-2-methylpropanoyl)-L-cysteine (SA96) in the blood and urine of the rat]. Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan, 1985, Volume: 105, Issue:7 Topics: Animals; Anti-Inflammatory Agents; Biotransformation; Cysteine; Male; Rats; Rats, Inbred Strains	1985
[Study on metabolism of the dithiol compound. II. Determination of N-(2-mercapto-2-methylpropanoyl)-L-cysteine (SA96) and its metabolites in the blood and urine of rats and dogs]. Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan, 1985, Volume: 105, Issue:7 Topics: Animals; Anti-Inflammatory Agents; Cysteine; Dogs; Male; Rats; Rats, Inbred Strains	1985
[Pharmacological studies of new sulfhydryl compounds 2-mercapto-2-methylpropanoyl-L-cysteine (SA96). I. Evaluation of anti-rheumatic action (author's transl)]. Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1980, Volume: 76, Issue:2 Topics: Acute Disease; Administration, Oral; Alkaline Phosphatase; Analgesics; Animals; Anti-Inflammatory Agents; Antibody Formation; Arthritis; Arthritis, Experimental; Body Temperature; Capillary Permeability; Cysteine; Edema; Male; Mice; Microbial Collagenase; Rats; Rheumatoid Factor; Sulfhydryl Compounds	1980
[Trends in the development of immunomodulators based physiopathological mechanisms of various types of hypersensitivities]. Nihon rinsho. Japanese journal of clinical medicine, 1983, Volume: 41, Issue:4 Topics: Adjuvants, Immunologic; Animals; Cysteine; Female; Gold; Hypersensitivity; Immunosuppressive Agents; Immunotherapy; Levamisole; Male; Mice; ortho-Aminobenzoates	1983
SA96: an immunopharmacological profile in vitro. International journal of tissue reactions, 1982, Volume: 4, Issue:1 Topics: Animals; Antibody Formation; Antibody-Producing Cells; Cattle; Concanavalin A; Cysteine; Dose-Response Relationship, Drug; Female; Fetal Blood; Lipopolysaccharides; Lymphocyte Activation; Lymphocytes; Mercaptoethanol; Mice; Mice, Inbred BALB C; Penicillamine; Spleen	1982
Yellow nail induced by bucillamine. International journal of dermatology, 1995, Volume: 34, Issue:7 Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Cysteine; Humans; Male; Nail Diseases	1995
The utility of chelating agents as antidotes for nephrotoxicity of gold sodium thiomalate in adjuvant-arthritic rats. Toxicology, 1995, Mar-31, Volume: 97, Issue:1-3 Topics: Animals; Antidotes; Arthritis, Experimental; Chelating Agents; Cysteine; Gold Sodium Thiomalate; Kidney; Male; Rats; Rats, Wistar; Unithiol	1995
[Immunoglobulin and LST in RA patients treated with bucillamine]. Ryumachi. [Rheumatism], 1995, Volume: 35, Issue:1 Topics: Aged; Arthritis, Rheumatoid; Cysteine; Female; Humans; Immunoglobulins; Lymphocyte Activation; Male; Middle Aged	1995
Eosinophilic bronchitis presenting with only severe dry cough due to bucillamine. Respiratory medicine, 1995, Volume: 89, Issue:3 Topics: Anti-Inflammatory Agents, Non-Steroidal; Bronchitis; Cough; Cysteine; Eosinophilia; Female; Humans; Middle Aged	1995
Effects of bucillamine, a new anti-rheumatic drug, on the experimental autoimmune uveitis in rats. Experimental eye research, 1994, Volume: 58, Issue:4 Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antibody Formation; Antigens; Arrestin; Autoimmune Diseases; Cell Division; Cells, Cultured; Concanavalin A; Cyclophosphamide; Cysteine; Drug Synergism; Eye Proteins; Immune Tolerance; Male; Rats; Rats, Inbred Lew; Spleen; Uveitis	1994
Comparative inhibitory effects of bucillamine and D-penicillamine on the function of human B cells and T cells. Arthritis and rheumatism, 1994, Volume: 37, Issue:6 Topics: Adult; B-Lymphocytes; Cysteine; Humans; Immunoglobulin M; Interferon-gamma; Interleukin-6; Penicillamine; T-Lymphocytes	1994
[A case of rheumatoid arthritis associated with agranulocytosis during bucillamine treatment]. Ryumachi. [Rheumatism], 1994, Volume: 34, Issue:3 Topics: Agranulocytosis; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Cysteine; Female; Humans; Middle Aged	1994
Immunopharmacological evaluation of bucillamine in rheumatoid arthritis. Drugs under experimental and clinical research, 1993, Volume: 19, Issue:5 Topics: Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; CD4 Antigens; Cysteine; Female; Flow Cytometry; Hemagglutination Tests; Humans; Male; Middle Aged; T-Lymphocyte Subsets	1993
Inhibition of mitogen-induced response of human peripheral blood mononuclear cells by bucillamine, a new antirheumatic sulfhydryl drug. Rheumatology international, 1994, Volume: 13, Issue:5 Topics: Anti-Inflammatory Agents, Non-Steroidal; Cell Division; Copper; Copper Sulfate; Cysteine; DNA; Humans; Hydrogen Peroxide; Leukocytes, Mononuclear; Mitogens; Penicillamine; Phytohemagglutinins	1994
Delayed-type skin allergic reaction in guinea pigs induced by anti-rheumatic compounds with sulfhydryl groups. Immunopharmacology and immunotoxicology, 1993, Volume: 15, Issue:4 Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Cysteine; Dermatitis, Allergic Contact; Drug Hypersensitivity; Guinea Pigs; Humans; Hypersensitivity, Delayed; Immunochemistry; Male; Species Specificity; Structure-Activity Relationship; Sulfhydryl Compounds	1993
[Immunoglobulin decrease accompanying adverse reactions with bucillamine]. Ryumachi. [Rheumatism], 1993, Volume: 33, Issue:4 Topics: Agammaglobulinemia; Aged; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Cysteine; Female; Humans; Immunoglobulin A; Immunoglobulin G; Immunoglobulin M; Male; Middle Aged	1993
[Analysis of the state of patients with rheumatoid arthritis using a personal computer]. Ryumachi. [Rheumatism], 1993, Volume: 33, Issue:2 Topics: Age Factors; Arthritis, Rheumatoid; Cysteine; Databases, Factual; Female; Gold Sodium Thiomalate; Humans; Male; Microcomputers; Middle Aged; Penicillamine; Quality of Life; Time Factors	1993
[Clinicopathological evaluation and treatment of bucillamine induced membranous nephropathy]. Ryumachi. [Rheumatism], 1993, Volume: 33, Issue:3 Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Cysteine; Female; Glomerulonephritis, Membranous; Humans; Kidney; Male; Middle Aged	1993
Immunosuppression by the disease modifying antirheumatic drug bucillamine: inhibition of human T lymphocyte function by bucillamine and its metabolites. The Journal of rheumatology, 1993, Volume: 20, Issue:6 Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Catalase; Cysteine; Humans; Immunosuppressive Agents; In Vitro Techniques; Interleukin-2; Lymphocyte Activation; Molecular Structure; T-Lymphocytes	1993
Regulation of B cell function by bucillamine, a novel disease-modifying antirheumatic drug. Clinical immunology and immunopathology, 1993, Volume: 66, Issue:1 Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; B-Lymphocytes; Copper; Cysteine; Depression, Chemical; Humans; Immunoglobulin M; Lymphocyte Activation; Penicillamine	1993
[Bucillamin induced lung injury in rheumatoid arthritis]. Ryumachi. [Rheumatism], 1996, Volume: 36, Issue:1 Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Cysteine; Diagnosis, Differential; Female; Humans; Lung Diseases; Male; Middle Aged; Tomography, X-Ray Computed	1996
Bucillamine induced pulmonary injury occurs with immunoglobulin decrease. The Journal of rheumatology, 1996, Volume: 23, Issue:7 Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Cysteine; Female; Humans; Immunoglobulin A; Immunoglobulin G; Immunoglobulin M; Immunoglobulins; Lung Diseases; Lung Diseases, Interstitial; Radiography	1996
Direct suppression of human synovial cell proliferation in vitro by salazosulfapyridine and bucillamine. The Journal of rheumatology, 1996, Volume: 23, Issue:1 Topics: Anti-Inflammatory Agents, Non-Steroidal; Antirheumatic Agents; Base Sequence; Cell Division; Cells, Cultured; Cysteine; Drug Combinations; Humans; Interleukins; Models, Biological; Molecular Sequence Data; Sulfasalazine; Synovial Membrane	1996
Covalent binding between bucillamine derivatives and human serum albumin. Pharmaceutical research, 1996, Volume: 13, Issue:9 Topics: Cysteine; Humans; Hydrogen-Ion Concentration; Kinetics; Oleic Acid; Protein Binding; Serum Albumin; Thermodynamics	1996
Effect of bucillamine on the rat trinitrobenzene sulfonic acid induced model of colitis. Inflammation research : official journal of the European Histamine Research Society ... [et al.], 1996, Volume: 45, Issue:10 Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Colitis; Cysteine; Male; Penicillamine; Rats; Rats, Wistar; Trinitrobenzenes	1996
[Effects of disease modifying antirheumatic drugs (DMARDs) and DEX on IL-1 beta and IL-6 production by IL-1 beta stimulated synovial culture cells]. Nihon Ika Daigaku zasshi, 1996, Volume: 63, Issue:5 Topics: Anti-Inflammatory Agents; Antirheumatic Agents; Cells, Cultured; Cysteine; Depression, Chemical; Dexamethasone; Gold Sodium Thiomalate; Humans; Interleukin-1; Interleukin-6; Methotrexate; Ribonucleosides; Sulfasalazine; Synovial Membrane; Tumor Necrosis Factor-alpha	1996
Generation of reactive oxygen species is required for bucillamine, a novel anti-rheumatic drug, to induce apoptosis in concert with copper. Immunopharmacology, 1997, Volume: 35, Issue:3 Topics: Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Arthritis, Rheumatoid; Cell Line; Copper; Cysteine; Drug Synergism; Humans; Monocytes; Reactive Oxygen Species	1997
The novel anti-rheumatic drug TA-383 has a macrophage migration enhancing activity. Japanese journal of pharmacology, 1997, Volume: 74, Issue:2 Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Reactive; Cell Movement; Chemotactic Factors; Collagen; Cysteine; Hypersensitivity, Delayed; Imidazoles; In Vitro Techniques; Macrophages, Alveolar; Mice; Mice, Inbred DBA; ortho-Aminobenzoates; Picryl Chloride; Rabbits; Sulfasalazine	1997
Differential influences of gold sodium thiomalate and bucillamine on the generation of CD14+ monocyte-lineage cells from bone marrow of rheumatoid arthritis patients. Clinical immunology and immunopathology, 1997, Volume: 84, Issue:3 Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Antirheumatic Agents; Arthritis, Rheumatoid; Bone Marrow; Bone Marrow Cells; Cell Lineage; Cysteine; Female; Gold Sodium Thiomalate; HLA-DR Antigens; Humans; Lipopolysaccharide Receptors; Male; Middle Aged; Monocytes	1997
Induction of drug resistance to gold sodium thiomalate in a monocyte cell line, THP-1. Clinical rheumatology, 1998, Volume: 17, Issue:3 Topics: Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; ATP Binding Cassette Transporter, Subfamily B, Member 1; Blotting, Western; Cell Line; Cysteine; Cytoplasm; Dose-Response Relationship, Drug; Drug Resistance; Fluorescent Antibody Technique, Indirect; Gold Sodium Thiomalate; Humans; Metallothionein; Monocytes; Sensitivity and Specificity	1998
Drug eruption due to bucillamine. Contact dermatitis, 1998, Volume: 39, Issue:2 Topics: Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Cysteine; Drug Eruptions; Female; Humans; Middle Aged; Patch Tests	1998
Pharmacological effects of SA96 (bucillamine) and its metabolites as immunomodulating drugs--the disulfide structure of SA-96 metabolites plays a critical role in the pharmacological action of the drug. International journal of immunopharmacology, 1998, Volume: 20, Issue:6 Topics: Adjuvants, Immunologic; Adult; Aged; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antirheumatic Agents; Arthritis, Rheumatoid; Cells, Cultured; Cysteine; Disulfides; Female; Gas Chromatography-Mass Spectrometry; Humans; Interleukin-6; Interleukin-8; Male; Middle Aged; Penicillamine; Rats; Structure-Activity Relationship; Synovial Fluid	1998
Effects of bucillamine and N-acetyl-L-cysteine on cytokine production and collagen-induced arthritis (CIA). Clinical and experimental immunology, 1999, Volume: 115, Issue:1 Topics: Acetylcysteine; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antibodies; Arthritis, Experimental; Cholesterol; Collagen; Cysteine; Humans; Male; Mice; Mice, Inbred DBA; NF-kappa B; Phospholipids; Rats; Rats, Wistar; Triglycerides; Tumor Cells, Cultured	1999
[A case of rheumatoid arthritis with bucillamine-induced myasthenia gravis treated by immunoadsorption therapy]. Ryumachi. [Rheumatism], 1999, Volume: 39, Issue:1 Topics: Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Cysteine; Female; Humans; Immunosorbent Techniques; Middle Aged; Myasthenia Gravis	1999
Down-regulation by bucillamine of lamina propria leucocytes in the rat colitis model. Clinical and experimental pharmacology & physiology, 1999, Volume: 26, Issue:12 Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Basement Membrane; Colitis; Cysteine; Disease Models, Animal; Down-Regulation; Leukocytes; Rats; Rats, Wistar	1999
Bucillamine suppresses human Th1 cell development by a hydrogen peroxide-independent mechanism. The Journal of rheumatology, 2000, Volume: 27, Issue:4 Topics: Anti-Inflammatory Agents, Non-Steroidal; Antirheumatic Agents; Arthritis, Rheumatoid; CD4-Positive T-Lymphocytes; Cell Differentiation; Cells, Cultured; Cysteine; Flow Cytometry; Humans; Hydrogen Peroxide; Interferon-gamma; Interleukin-12; Interleukin-2; Interleukin-4; Leukocyte Common Antigens; Oxidants; Penicillamine; Th1 Cells	2000
Effects of sulfhydryl compounds on interleukin-1-induced vascular endothelial growth factor production in human synovial stromal cells. Biological & pharmaceutical bulletin, 2000, Volume: 23, Issue:5 Topics: Acetylcysteine; Cells, Cultured; Cysteine; Endothelial Growth Factors; Humans; Interleukin-1; Lymphokines; Penicillamine; Stromal Cells; Sulfhydryl Compounds; Synovial Membrane; Tiopronin; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors	2000
In vitro and in vivo inhibition of activation induced T cell apoptosis by bucillamine. The Journal of rheumatology, 2000, Volume: 27, Issue:6 Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antibodies; Antirheumatic Agents; Apoptosis; Arthritis, Rheumatoid; B-Lymphocytes; CD3 Complex; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes; Cysteine; Dexamethasone; Enterotoxins; Flow Cytometry; Glucocorticoids; Hybridomas; In Vitro Techniques; Interleukin-2; Lymphocyte Activation; Mice; Mice, Inbred BALB C; Penicillamine; Reactive Oxygen Species; Superantigens; Thymus Gland	2000
Bucillamine-induced nephropathy in a child with juvenile rheumatoid arthritis and Kartagener's syndrome. Pediatrics international : official journal of the Japan Pediatric Society, 2000, Volume: 42, Issue:3 Topics: Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Juvenile; Child; Creatinine; Cysteine; Glomerulonephritis, Membranous; Humans; Kartagener Syndrome; Kidney; Male	2000
Novel in vitro effects of bucillamine: inhibitory effects on proinflammatory cytokine production and transendothelial migration of T cells. Arthritis and rheumatism, 2000, Volume: 43, Issue:7 Topics: Anti-Inflammatory Agents, Non-Steroidal; Cell Movement; Cell Survival; Cells, Cultured; Cysteine; Endothelium, Vascular; Humans; Lymphocyte Activation; Lymphokines; Phytohemagglutinins; T-Lymphocytes	2000
Increased MDR1 P-glycoprotein expression in methotrexate resistance: comment on the article by Yudoh et al. Arthritis and rheumatism, 2000, Volume: 43, Issue:7 Topics: Antirheumatic Agents; Arthritis, Rheumatoid; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cysteine; Drug Interactions; Drug Resistance, Multiple; Humans; Methotrexate; Sulfasalazine; Th1 Cells	2000
Imbalance in production between vascular endothelial growth factor and endostatin in patients with rheumatoid arthritis. The Journal of rheumatology, 2000, Volume: 27, Issue:10 Topics: Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Collagen; Cysteine; Drug Therapy, Combination; Endostatins; Endothelial Growth Factors; Enzyme-Linked Immunosorbent Assay; Fibroblast Growth Factor 2; Humans; Lymphokines; Middle Aged; Osteoarthritis; Peptide Fragments; Prednisolone; Sulfasalazine; Synovial Fluid; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors	2000
Effects of combinations of anti-rheumatic drugs on the production of vascular endothelial growth factor and basic fibroblast growth factor in cultured synoviocytes and patients with rheumatoid arthritis. Rheumatology (Oxford, England), 2000, Volume: 39, Issue:11 Topics: Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Antirheumatic Agents; Arthritis, Rheumatoid; C-Reactive Protein; Cells, Cultured; Cysteine; Dexamethasone; Drug Synergism; Drug Therapy, Combination; Endothelial Growth Factors; Fibroblast Growth Factor 2; Gold Sodium Thiomalate; Humans; In Vitro Techniques; Lipopolysaccharides; Lymphokines; Methotrexate; Sulfasalazine; Synovial Membrane; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors	2000
Drug-induced pemphigus foliaceus with features of pemphigus vulgaris. The British journal of dermatology, 2001, Volume: 144, Issue:2 Topics: Anti-Inflammatory Agents, Non-Steroidal; Cysteine; Drug Eruptions; Humans; Male; Middle Aged; Pemphigus	2001
[A case of drug-induced interstitial pneumonitis in rheumatoid arthritis treated with bucillamine]. Nihon Kokyuki Gakkai zasshi = the journal of the Japanese Respiratory Society, 2001, Volume: 39, Issue:1 Topics: Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Cysteine; Female; Humans; Lung Diseases, Interstitial; Lymphocyte Activation; Middle Aged; Thoracic Surgery, Video-Assisted	2001
Effects of KE-758; an active metabolite of the new anti-rheumatic drug KE-298, D-penicillamine, bucillamine and auranofin on the proliferation of murine lymphocytes, and the production of nitric oxide by murine macrophages. International immunopharmacology, 2001, Volume: 1, Issue:5 Topics: Animals; Antirheumatic Agents; Auranofin; Cell Division; Cell Line; Concanavalin A; Cysteine; Female; Hydrogen Peroxide; In Vitro Techniques; Interferon-gamma; Ionomycin; Lipopolysaccharides; Lymphocyte Activation; Lymphocytes; Macrophages; Mice; Mice, Inbred DBA; Nitric Oxide; Penicillamine; Phenylpropionates; Recombinant Proteins; Tetradecanoylphorbol Acetate	2001
A case of BOOP developed during bucillamine treatment for rheumatoid. The Korean journal of internal medicine, 2001, Volume: 16, Issue:1 Topics: Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Biopsy, Needle; Cryptogenic Organizing Pneumonia; Cysteine; Follow-Up Studies; Humans; Male; Middle Aged; Radiography, Thoracic; Risk Assessment; Tomography, X-Ray Computed	2001
Cutaneous drug reaction case reports: from the world literature. American journal of clinical dermatology, 2001, Volume: 2, Issue:4 Topics: Adolescent; Adverse Drug Reaction Reporting Systems; Aged; Amlodipine; Anti-Bacterial Agents; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Anticoagulants; Anticonvulsants; Antihypertensive Agents; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Antirheumatic Agents; BCG Vaccine; Cefotetan; Cephamycins; Contrast Media; Cysteine; Dapsone; Diltiazem; Dipyrone; Docetaxel; Drug Eruptions; Echinacea; Enoxaparin; Female; Fructose; Glucans; Glucose; Gold Sodium Thiomalate; Humans; Ibuprofen; Icodextrin; Ioxaglic Acid; Male; Middle Aged; Minocycline; Paclitaxel; Pregnancy; Solvents; Taxoids; Topiramate; Triamcinolone; Trichloroethylene	2001
Bucillamine prevents myocardial reperfusion injury. Journal of cardiovascular pharmacology, 2001, Volume: 38, Issue:6 Topics: Animals; Cells, Cultured; Collateral Circulation; Coronary Circulation; Cysteine; Dogs; Dose-Response Relationship, Drug; Hydrogen Peroxide; Kinetics; L-Lactate Dehydrogenase; Myocardial Infarction; Myocardial Reperfusion Injury; Myocardium; Rats; Single-Blind Method; Sulfhydryl Compounds; Tiopronin	2001
Thiol antioxidants inhibit the adjuvant effects of aerosolized diesel exhaust particles in a murine model for ovalbumin sensitization. Journal of immunology (Baltimore, Md. : 1950), 2002, Mar-01, Volume: 168, Issue:5 Topics: Acetylcysteine; Adjuvants, Immunologic; Administration, Inhalation; Aerosols; Animals; Antioxidants; Cell Line; Cysteine; Hypersensitivity, Immediate; Immunoglobulin E; Immunoglobulin G; Lipid Peroxidation; Lung; Mice; Ovalbumin; Oxidative Stress; Sulfhydryl Compounds; Vehicle Emissions	2002
Bucillamine induces membranous glomerulonephritis. American journal of kidney diseases : the official journal of the National Kidney Foundation, 2002, Volume: 39, Issue:4 Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Cysteine; Dose-Response Relationship, Drug; Female; Glomerulonephritis, Membranous; Humans; Male; Middle Aged; Proteinuria	2002
[A case of rheumatoid arthritis complicated with a pneumonitis during concomitant treatment with methotrexate and bucillamine]. Ryumachi. [Rheumatism], 2002, Volume: 42, Issue:1 Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Antirheumatic Agents; Arthritis, Rheumatoid; Cysteine; Female; Humans; Methotrexate; Pneumonia	2002
Bucillamine, a thiol antioxidant, prevents transplantation-associated reperfusion injury. Proceedings of the National Academy of Sciences of the United States of America, 2002, Jun-25, Volume: 99, Issue:13 Topics: Animals; Antioxidants; Cysteine; Disease Models, Animal; Glutathione; Male; Organ Transplantation; Rats; Rats, Sprague-Dawley; Rats, Zucker; Reperfusion Injury	2002
Gigantomastia induced by bucillamine. Annals of plastic surgery, 2002, Volume: 49, Issue:2 Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Breast; Breast Diseases; Cysteine; Female; Humans; Hyperplasia; Hypertrophy; Mammaplasty; Treatment Outcome	2002
Inhibitory effect of bucillamine on laser-induced choroidal neovascularization in rats. Current eye research, 2002, Volume: 24, Issue:1 Topics: Animals; Antioxidants; Choroidal Neovascularization; Cysteine; Fluorescein Angiography; Indocyanine Green; Laser Coagulation; Male; Rats; Rats, Inbred BN	2002
Subconjunctival administration of bucillamine suppresses choroidal neovascularization in rat. Investigative ophthalmology & visual science, 2002, Volume: 43, Issue:11 Topics: Animals; Antirheumatic Agents; Choroid; Choroidal Neovascularization; Chromatography, High Pressure Liquid; Conjunctiva; Cysteine; Disease Models, Animal; Endothelial Growth Factors; Female; Fluorescein Angiography; Gas Chromatography-Mass Spectrometry; Injections; Intercellular Signaling Peptides and Proteins; Lymphokines; Platelet Endothelial Cell Adhesion Molecule-1; Rats; Rats, Inbred BN; Retina; Sclera; Tissue Distribution; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors	2002
Inhibitory mechanism of vascular endothelial growth factor (VEGF) by bucillamine. British journal of pharmacology, 2002, Volume: 137, Issue:6 Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cattle; Cell Hypoxia; Cell Line; Cells, Cultured; Cysteine; DNA-Binding Proteins; Dose-Response Relationship, Drug; Endothelial Growth Factors; Endothelium, Vascular; Gene Expression Regulation; Hypoxia-Inducible Factor 1; Hypoxia-Inducible Factor 1, alpha Subunit; Intercellular Signaling Peptides and Proteins; Luciferases; Lymphokines; Nuclear Proteins; Promoter Regions, Genetic; Protein Binding; Recombinant Fusion Proteins; RNA Stability; RNA, Messenger; Sp1 Transcription Factor; Transcription Factor AP-1; Transcription Factor AP-2; Transcription Factors; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors	2002
Inhibitory effects of bucillamine on increased blood-retinal barrier permeability in streptozotocin-induced diabetic rats. Current eye research, 2002, Volume: 25, Issue:1 Topics: Animals; Antioxidants; Blood-Retinal Barrier; Capillary Permeability; Cysteine; Diabetes Mellitus, Experimental; Glutathione; Glutathione Disulfide; Hydrogen Peroxide; Male; Oxidative Stress; Rats; Rats, Wistar; Reactive Oxygen Species; Retinal Vessels	2002
KE-758, an active metabolite of the new anti-rheumatic drug KE-298, suppresses production of tumor necrosis factor-alpha and interleukin-1 beta in THP-1, a human monocyte cell line. Drugs under experimental and clinical research, 2002, Volume: 28, Issue:5 Topics: Antirheumatic Agents; Auranofin; Cell Line; Cysteine; Enzyme-Linked Immunosorbent Assay; Humans; Interferon-gamma; Interleukin-1; Lipopolysaccharides; Monocytes; Penicillamine; Phenylbutyrates; Phenylpropionates; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tumor Necrosis Factor-alpha	2002
Bucillamine induces the synthesis of vascular endothelial growth factor dose-dependently in systemic sclerosis fibroblasts via nuclear factor-kappaB and simian virus 40 promoter factor 1 pathways. Molecular pharmacology, 2004, Volume: 65, Issue:2 Topics: Cells, Cultured; Cysteine; Dose-Response Relationship, Drug; Fibroblasts; Humans; NF-kappa B; Plicamycin; RNA, Messenger; Scleroderma, Systemic; Simian virus 40; Sp1 Transcription Factor; Vascular Endothelial Growth Factor A	2004
Inhibitory effects of bucillamine on the expression of vascular cell adhesion molecule-1 in human umbilical vein endothelial cells. International immunopharmacology, 2004, Volume: 4, Issue:1 Topics: Anti-Inflammatory Agents, Non-Steroidal; Cells, Cultured; Cysteine; Disulfides; Dose-Response Relationship, Drug; E-Selectin; Endothelium, Vascular; Humans; Intercellular Adhesion Molecule-1; Umbilical Veins; Vascular Cell Adhesion Molecule-1	2004
Quantitative analysis of bucillamine in blood using high-performance liquid chromatography-mass spectrometry technique. Biomedical chromatography : BMC, 2004, Volume: 18, Issue:10 Topics: Anti-Inflammatory Agents, Non-Steroidal; Chromatography, High Pressure Liquid; Cysteine; Drug Stability; Humans; Mass Spectrometry; Sensitivity and Specificity	2004
Patients with rheumatoid arthritis (RA) and proteinuria. Clinical and experimental nephrology, 2004, Volume: 8, Issue:3 Topics: Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Cysteine; Humans; Proteinuria	2004
[Examination of the escape phenomenon in disease modifying antirheumatic drugs]. Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan, 2005, Volume: 125, Issue:3 Topics: Aged; Antirheumatic Agents; Arthritis, Rheumatoid; Blood Sedimentation; C-Reactive Protein; Cysteine; Drug Therapy, Combination; Female; Humans; Male; Methotrexate; Middle Aged; Phenylacetates; Recurrence; Secondary Prevention; Sulfasalazine	2005
Quantitative analysis of bucillamine and its pharmaceutical formulation using FT-IR spectroscopy. Farmaco (Societa chimica italiana : 1989), 2005, Volume: 60, Issue:8 Topics: Cysteine; Least-Squares Analysis; Molecular Structure; Pharmaceutical Preparations; Principal Component Analysis; Spectroscopy, Fourier Transform Infrared; Tablets	2005
The inhibitory effect of disease-modifying anti-rheumatic drugs and steroids on gliostatin/platelet-derived endothelial cell growth factor production in human fibroblast-like synoviocytes. Rheumatology international, 2005, Volume: 25, Issue:8 Topics: Adrenal Cortex Hormones; Adult; Aged; Antirheumatic Agents; Arthritis, Rheumatoid; Cells; Cells, Cultured; Cysteine; Dexamethasone; Elbow; Female; Fibroblasts; Humans; Knee; Methotrexate; Middle Aged; Organogold Compounds; Orthopedic Procedures; Penicillamine; Phenylacetates; Sulfasalazine; Synovial Membrane; Thymidine Phosphorylase	2005
A case of interstitial pneumonia caused by bucillamine: a study using serological markers. Modern rheumatology, 2006, Volume: 16, Issue:1 Topics: Anti-Inflammatory Agents, Non-Steroidal; Antigens, Neoplasm; Biomarkers; Cysteine; Humans; Lung Diseases, Interstitial; Male; Middle Aged; Mucin-1; Mucins; Pulmonary Surfactant-Associated Protein A; Pulmonary Surfactant-Associated Protein D	2006
Efficacy and safety of bucillamine, a D-penicillamine analogue, in patients with active rheumatoid arthritis. Modern rheumatology, 2006, Volume: 16, Issue:2 Topics: Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; C-Reactive Protein; Cysteine; Female; Humans; Joints; Male; Methotrexate; Middle Aged; Retrospective Studies; Severity of Illness Index; Treatment Outcome	2006
Outcome and treatment of bucillamine-induced nephropathy. Nephron. Clinical practice, 2006, Volume: 104, Issue:1 Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Cysteine; Drug Administration Schedule; Female; Glomerulonephritis, Membranous; Humans; Kidney; Male; Middle Aged; Proteinuria; Remission Induction	2006
Bucillamine-induced pemphigus vulgaris in a patient with rheumatoid arthritis and polymyositis overlap syndrome. Journal of Korean medical science, 2006, Volume: 21, Issue:3 Topics: Antioxidants; Arthritis; Arthritis, Rheumatoid; Biopsy; Cysteine; Female; Humans; Middle Aged; Pemphigus; Polymyositis; Skin; Syndrome	2006
Bucillamine induces glutathione biosynthesis via activation of the transcription factor Nrf2. Biochemical pharmacology, 2006, Aug-14, Volume: 72, Issue:4 Topics: Active Transport, Cell Nucleus; Animals; Blotting, Northern; Blotting, Western; Carcinoma, Hepatocellular; Catalytic Domain; Cell Line, Tumor; Cell Nucleus; Cysteine; Gene Expression; Glutamate-Cysteine Ligase; Glutathione; Humans; Membrane Transport Proteins; Molecular Structure; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; NF-E2 Transcription Factor, p45 Subunit; RNA, Messenger	2006
Radiographic appearance of bronchiolitis obliterans organizing pneumonia (BOOP) developing during Bucillamine treatment for rheumatoid arthritis. The American journal of the medical sciences, 2006, Volume: 332, Issue:1 Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Cryptogenic Organizing Pneumonia; Cysteine; Female; Humans; Lung; Radiography	2006
Antioxidant properties of bucillamine: possible mode of action. Biochemical and biophysical research communications, 2006, Oct-27, Volume: 349, Issue:3 Topics: Antioxidants; Chelating Agents; Copper; Cysteine; Electrochemistry; Free Radicals; Oxidation-Reduction; Spectrum Analysis	2006
Yellow nails under bucillamine therapy for rheumatoid arthritis: a report of two cases. Rheumatology international, 2007, Volume: 27, Issue:6 Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Cysteine; Female; Humans; Middle Aged; Nail Diseases; Pigmentation Disorders	2007
Scientific basis for the efficacy of combined use of antirheumatic drugs against bone destruction in rheumatoid arthritis. Modern rheumatology, 2007, Volume: 17, Issue:1 Topics: Animals; Antirheumatic Agents; Arthritis, Rheumatoid; Bone Resorption; Cell Differentiation; Cells, Cultured; Coculture Techniques; Cysteine; Dose-Response Relationship, Drug; Drug Therapy, Combination; Methotrexate; Mice; Mice, Inbred C57BL; NFATC Transcription Factors; Osteoclasts; RANK Ligand; Sulfasalazine	2007
Ten years results of bucillamine in the treatment of rheumatoid arthritis. Modern rheumatology, 2007, Volume: 17, Issue:1 Topics: Adult; Aged; Antirheumatic Agents; Arthritis, Rheumatoid; Cohort Studies; Cysteine; Female; Follow-Up Studies; Humans; Male; Middle Aged; Patient Dropouts; Severity of Illness Index; Treatment Outcome	2007
A case of bucillamine-induced interstitial pneumonia with positive lymphocyte stimulation test for bucillamine using bronchoalveolar lavage lymphocytes. Internal medicine (Tokyo, Japan), 2007, Volume: 46, Issue:20 Topics: Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Bronchoalveolar Lavage Fluid; Cysteine; Female; Humans; Lung; Lung Diseases, Interstitial; Lymphocyte Activation; Middle Aged; Radiography	2007
Hemophagocytic syndrome associated with rheumatoid arthritis. Internal medicine (Tokyo, Japan), 2007, Volume: 46, Issue:21 Topics: Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Cysteine; Female; Humans; Lymphohistiocytosis, Hemophagocytic; Middle Aged	2007
Eosinophilic pneumonia (EP) associated with rheumatoid arthritis in which drug-induced eosinophilic pneumonia could be ruled out. Internal medicine (Tokyo, Japan), 2008, Volume: 47, Issue:6 Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Antirheumatic Agents; Arthritis, Rheumatoid; Cysteine; Diagnosis, Differential; Glucocorticoids; Humans; Male; Methotrexate; Prednisolone; Pulmonary Eosinophilia	2008
The efficacy and safety of bucillamine as a second-line DMARD in the treatment of rheumatoid arthritis: a retrospective cohort study. Modern rheumatology, 2008, Volume: 18, Issue:6 Topics: Anti-Inflammatory Agents, Non-Steroidal; Antirheumatic Agents; Arthritis, Rheumatoid; Cohort Studies; Cysteine; Female; Health Status; Humans; Joints; Male; Middle Aged; Remission Induction; Retrospective Studies; Severity of Illness Index; Treatment Outcome	2008
Prolonged administration of a dithiol antioxidant protects against ventricular remodeling due to ischemia-reperfusion in mice. American journal of physiology. Heart and circulatory physiology, 2008, Volume: 295, Issue:3 Topics: Animals; Antioxidants; Body Weight; Cysteine; Cytokines; Female; Fetus; Gene Expression; Heart Function Tests; Mice; Mice, Inbred C57BL; Myocardial Contraction; Myocardial Infarction; Myocardial Reperfusion Injury; Myocardium; Nuclease Protection Assays; Organ Size; Pregnancy; Ventricular Dysfunction, Left; Ventricular Remodeling	2008
[False-positive reaction of urinary ketone bodies caused by bucillamine]. Rinsho byori. The Japanese journal of clinical pathology, 2008, Volume: 56, Issue:7 Topics: Aged; Antirheumatic Agents; Arthritis, Rheumatoid; Biomarkers; Cysteine; False Positive Reactions; Female; Humans; Ketone Bodies; Male; Middle Aged	2008
Etanercept improved primary biliary cirrhosis associated with rheumatoid arthritis. Joint bone spine, 2009, Volume: 76, Issue:1 Topics: Anti-Inflammatory Agents, Non-Steroidal; Antirheumatic Agents; Arthritis, Rheumatoid; Cysteine; Drug Therapy, Combination; Etanercept; Female; Humans; Immunoglobulin G; Liver Cirrhosis, Biliary; Methotrexate; Middle Aged; Prednisolone; Receptors, Tumor Necrosis Factor; Treatment Outcome; Withholding Treatment	2009
Differential influences of bucillamine and methotrexate on the generation of fibroblast-like cells from bone marrow CD34+ cells of rheumatoid arthritis patients. International immunopharmacology, 2009, Volume: 9, Issue:1 Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Antigens, CD34; Antirheumatic Agents; Arthritis, Rheumatoid; Bone Marrow Cells; Culture Media; Cysteine; Female; Fibroblasts; Fluorescent Antibody Technique; Humans; Ilium; Immunosuppressive Agents; Indicators and Reagents; Matrix Metalloproteinase 1; Methotrexate; Middle Aged; Stem Cells; Vimentin	2009
The investigation of synovial genomic targets of bucillamine with microarray technique. Inflammation research : official journal of the European Histamine Research Society ... [et al.], 2009, Volume: 58, Issue:9 Topics: Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Cells, Cultured; Cysteine; Gene Expression Profiling; Gene Expression Regulation; Humans; Interleukin-1beta; Microarray Analysis; Molecular Sequence Data; Molecular Structure; Signal Transduction; Synovial Membrane	2009
Development and validation of a reversed-phase fluorescence HPLC method for determination of bucillamine in human plasma using pre-column derivatization with monobromobimane. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2009, Jul-15, Volume: 877, Issue:22 Topics: Antirheumatic Agents; Bridged Bicyclo Compounds; Chromatography, High Pressure Liquid; Cysteine; Fluorescent Dyes; Humans; Male	2009
Radiographic repair in three Japanese patients with rheumatoid arthritis treated with bucillamine. Modern rheumatology, 2009, Volume: 19, Issue:6 Topics: Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Arthrography; Bone and Bones; Cysteine; Disease Progression; Female; Humans; Joints; Male; Middle Aged; Recovery of Function; Severity of Illness Index; Treatment Outcome	2009
N-(tert)-butyloxycarbonyl)-beta,beta-cyclopentyl-cysteine (acetamidomethyl)-methyl ester for synthesis of novel peptidomimetic derivatives. Protein and peptide letters, 2010, Volume: 17, Issue:7 Topics: Biomimetic Materials; Cyclopentanes; Cysteine; Furans; Peptides; Sodium Compounds; Sulfhydryl Compounds; Thermodynamics	2010
Combined effects of bucillamine and etanercept on a rat type II collagen-induced arthritis model. Modern rheumatology, 2010, Volume: 20, Issue:4 Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antirheumatic Agents; Arthritis, Experimental; Arthritis, Rheumatoid; Cysteine; Disease Models, Animal; Drug Synergism; Drug Therapy, Combination; Etanercept; Female; Granulocyte-Macrophage Colony-Stimulating Factor; Immunoglobulin G; Immunoglobulin M; Interleukin-1alpha; Interleukin-6; Rats; Rats, Inbred Lew; Receptors, Tumor Necrosis Factor	2010
Organizing pneumonia in a patient with rheumatoid arthritis treated with etanercept. Modern rheumatology, 2010, Volume: 20, Issue:6 Topics: Antirheumatic Agents; Arthritis, Rheumatoid; Cryptogenic Organizing Pneumonia; Cysteine; Drug Therapy, Combination; Etanercept; Female; Humans; Immunoglobulin G; Methotrexate; Middle Aged; Radiography, Thoracic; Receptors, Tumor Necrosis Factor; Treatment Outcome	2010
Attenuation of warm ischemia-reperfusion injury in the liver by bucillamine through decreased neutrophil activation and Bax/Bcl-2 modulation. Journal of gastroenterology and hepatology, 2010, Volume: 25, Issue:12 Topics: Alanine Transaminase; Animals; Antioxidants; Apoptosis; Aspartate Aminotransferases; bcl-2-Associated X Protein; Cell Adhesion; Chemokine CXCL1; Cysteine; Disease Models, Animal; F2-Isoprostanes; Glutathione; Liver; Male; Neutrophil Activation; Oxidative Stress; Proto-Oncogene Proteins c-bcl-2; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Reverse Transcriptase Polymerase Chain Reaction; Time Factors; Warm Ischemia	2010
Etanercept in combination with conventional disease-modifying antirheumatic drugs (DMARDs) in the treatment of rheumatoid arthritis patients intolerant to methotrexate. Modern rheumatology, 2012, Volume: 22, Issue:1 Topics: Adult; Aged; Aged, 80 and over; Antirheumatic Agents; Arthritis, Rheumatoid; Cysteine; Drug Substitution; Drug Therapy, Combination; Etanercept; Female; Glucocorticoids; Humans; Immunoglobulin G; Joints; Male; Methotrexate; Middle Aged; Pain Measurement; Receptors, Tumor Necrosis Factor; Recovery of Function; Retrospective Studies; Severity of Illness Index; Sulfasalazine; Treatment Failure	2012
Single-center, retrospective analysis of efficacy and safety of tacrolimus as a second-line DMARD in combination therapy and the risk factors contributing to adverse events in 115 patients with rheumatoid arthritis. Clinical rheumatology, 2012, Volume: 31, Issue:2 Topics: Adult; Aged; Antirheumatic Agents; Arthritis, Rheumatoid; Cysteine; Disease Progression; Drug Therapy, Combination; Female; Humans; Male; Methotrexate; Middle Aged; Retrospective Studies; Risk Factors; Severity of Illness Index; Sulfasalazine; Tacrolimus; Treatment Outcome	2012
Free-radical degradation of high-molecular-weight hyaluronan induced by ascorbate plus cupric ions. Testing of bucillamine and its SA981-metabolite as antioxidants. Journal of pharmaceutical and biomedical analysis, 2011, Nov-01, Volume: 56, Issue:3 Topics: Antioxidants; Antirheumatic Agents; Ascorbic Acid; Cations; Copper; Cysteine; Free Radicals; Hyaluronic Acid; Hydroxyl Radical; Molecular Weight; Oxidation-Reduction; Penicillamine; Peroxides; Viscosity	2011
Proximal tubules and podocytes are toxicity targets of bucillamine in a mouse model of drug-induced kidney injury. European journal of pharmacology, 2011, Nov-16, Volume: 670, Issue:1 Topics: Acute Kidney Injury; Animals; Cysteine; Disease Models, Animal; Kidney Tubules, Proximal; Male; Mice; Mice, Inbred BALB C; Nephrectomy; Oligonucleotide Array Sequence Analysis; Podocytes; Proteinuria; Transcriptome; Up-Regulation	2011
Recent trends in use of nonbiologic DMARDs and evaluation of their continuation rates in single and dual combination therapies in rheumatoid arthritis patients in Japan. Modern rheumatology, 2012, Volume: 22, Issue:6 Topics: Adult; Antirheumatic Agents; Arthritis, Rheumatoid; Cysteine; Drug Therapy, Combination; Female; Humans; Japan; Male; Methotrexate; Practice Patterns, Physicians'; Severity of Illness Index; Sulfasalazine; Treatment Outcome	2012
Bucillamine inhibits CD40-mediated Akt activation and antibody production in mouse B-cell lymphoma. International immunopharmacology, 2012, Volume: 14, Issue:1 Topics: Animals; Antibody Formation; CD40 Antigens; Cell Line, Tumor; Cell Proliferation; Cysteine; Enzyme Activation; Methotrexate; Mice; Oncogene Protein v-akt; Phosphorylation	2012
[Anti-rheumatic drugs]. Nihon rinsho. Japanese journal of clinical medicine, 2012, Volume: 70 Suppl 6 Topics: Antirheumatic Agents; Cysteine; Hematologic Diseases; Humans; Hypersensitivity; Infections; Isoxazoles; Kidney Diseases; Leflunomide; Liver Neoplasms; Lung Diseases; Methotrexate	2012
[Rheumatoid arthritis: progress in diagnosis and treatment. Topics: IV. Treatment; 2. Antirheumatic agents, 1) non-biologic agents]. Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine, 2012, Oct-10, Volume: 101, Issue:10 Topics: Antirheumatic Agents; Arthritis, Rheumatoid; Cysteine; Female; Humans; Methotrexate; Sulfasalazine; Tacrolimus	2012
Free-radical degradation of high-molar-mass hyaluronan induced by Weissberger's oxidative system: potential antioxidative effect of bucillamine. Neuro endocrinology letters, 2012, Volume: 33 Suppl 3 Topics: Antioxidants; Ascorbic Acid; Copper; Cysteine; Extracellular Matrix; Free Radicals; Humans; Hyaluronic Acid; Molecular Weight; Oxidation-Reduction; Spectroscopy, Fourier Transform Infrared; Viscosity	2012
Effective treatment of a steroid-induced femoral neck fracture nonunion with a once-weekly administration of teriparatide in a rheumatoid patient: a case report. Archives of osteoporosis, 2013, Volume: 8 Topics: Aged, 80 and over; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Bone Density Conservation Agents; Cysteine; Female; Femoral Neck Fractures; Fractures, Ununited; Glucocorticoids; Humans; Osteoporosis; Prednisolone; Teriparatide; Treatment Outcome	2013
S,S'-dinitrosobucillamine, a new nitric oxide donor, induces a better vasorelaxation than other S-nitrosothiols. European journal of pharmacology, 2014, May-05, Volume: 730 Topics: Animals; Aorta; Chemical Phenomena; Cysteine; Drug Stability; In Vitro Techniques; Male; Nitric Oxide Donors; Nitroso Compounds; Protein Disulfide-Isomerases; Rats; S-Nitrosothiols; Vasodilation; Vasodilator Agents	2014
Bucillamine-induced pemphigus vulgaris. Journal of the European Academy of Dermatology and Venereology : JEADV, 2015, Volume: 29, Issue:6 Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Cysteine; Drug Eruptions; Female; Humans; Pemphigus	2015
Bucillamine prevents cisplatin-induced ototoxicity through induction of glutathione and antioxidant genes. Experimental & molecular medicine, 2015, Feb-20, Volume: 47 Topics: Animals; Antioxidants; Apoptosis; Caspase 3; Caspase 8; Cell Line; Cisplatin; Cysteine; Gene Expression Regulation; Gene Knockdown Techniques; Glutathione; Heme Oxygenase-1; Intracellular Space; Male; Metabolic Detoxication, Phase II; Mice; NF-E2-Related Factor 2; Nitric Oxide; Organ of Corti; Rats; Reactive Oxygen Species; RNA Interference; Superoxide Dismutase	2015
The usefulness of a new triple combination treatment utilizing methotrexate, salazosulfapyridine, and bucillamine in rheumatoid arthritis. Modern rheumatology, 2016, Volume: 26, Issue:1 Topics: Adult; Aged; Antirheumatic Agents; Arthritis, Rheumatoid; Biological Products; Cysteine; Drug Therapy, Combination; Female; Humans; Japan; Male; Methotrexate; Middle Aged; Sulfasalazine; Treatment Outcome	2016
Kinetics of ABTS derived radical cation scavenging by bucillamine, cysteine, and glutathione. Catalytic effect of Cu(2+) ions. Biophysical chemistry, 2016, Volume: 212 Topics: Antirheumatic Agents; Benzothiazoles; Catalysis; Cations, Divalent; Copper; Cysteine; Free Radical Scavengers; Glutathione; Sulfonic Acids	2016
Hyperplasia of Lymphoid Follicles and Lymphangiectasia in the Parietal Pleura in Bucillamine-induced Yellow Nail Syndrome. Internal medicine (Tokyo, Japan), 2018, Jul-01, Volume: 57, Issue:13 Topics: Adrenal Cortex Hormones; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Cysteine; Female; Humans; Hyperplasia; Inflammation; Lymphangiectasis; Lymphedema; Pleurisy; Yellow Nail Syndrome	2018
Bucillamine-induced Pneumonitis in a Patient with Rheumatoid Arthritis-associated Interstitial Pneumonia: A Case Report and Review of the Literature. Internal medicine (Tokyo, Japan), 2019, Aug-01, Volume: 58, Issue:15 Topics: Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Bronchoalveolar Lavage Fluid; Cysteine; Dyspnea; Female; Humans; Hypoxia; Lung; Lung Diseases, Interstitial; Lymphocyte Count; Pneumonia; Tomography, X-Ray Computed	2019
Bucillamine-induced Pneumonitis in a Patient with Rheumatoid Arthritis-associated Interstitial Pneumonia: A Case Report and Review of the Literature. Internal medicine (Tokyo, Japan), 2019, 12-01, Volume: 58, Issue:23 Topics: Arthritis, Rheumatoid; Cysteine; Humans; Lung Diseases, Interstitial; Patients; Pneumonia	2019
Bucillamine-induced Pneumonitis in a Patient with Rheumatoid Arthritis-associated Interstitial Pneumonia: A Case Report and Review of the Literature - Reply. Internal medicine (Tokyo, Japan), 2019, 12-01, Volume: 58, Issue:23 Topics: Arthritis, Rheumatoid; Cysteine; Humans; Lung Diseases, Interstitial; Patients; Pneumonia	2019
Bucillamine-induced gigantomastia with galactorrhea and hyperprolactinaemia. Modern rheumatology case reports, 2020, Volume: 4, Issue:1 Topics: Anti-Inflammatory Agents, Non-Steroidal; Breast; Cysteine; Disease Susceptibility; Female; Galactorrhea; Humans; Hyperprolactinemia; Hypertrophy; Japan; Republic of Korea	2020
Bucillamine in the treatment of patients with mild to moderate COVID-19: an interview with Michael Frank. Future microbiology, 2022, Volume: 17 Topics: Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Clinical Trials, Phase III as Topic; COVID-19; COVID-19 Drug Treatment; Cysteine; Drug Industry; Drug Repositioning; Gout; Humans	2022