cysteine has been researched along with aspartic acid in 554 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 168 (30.32) | 18.7374 |
| 1990's | 119 (21.48) | 18.2507 |
| 2000's | 192 (34.66) | 29.6817 |
| 2010's | 50 (9.03) | 24.3611 |
| 2020's | 25 (4.51) | 2.80 |
| Authors | Studies |
|---|---|
| Petz, D; Schneider, F | 1 |
| Gebhart, E | 1 |
| Umbarger, HE | 1 |
| Iacobazzi, V; Palmieri, F; Stipani, I | 2 |
| Olney, JW | 3 |
| Casey, R; Lang, A | 1 |
| Rassin, DK; Sturman, JA | 1 |
| Bayer, E; Hemmasi, B | 1 |
| Hewitt, JA; Kilmartin, JV; Wootton, JF | 1 |
| Kochakian, CD | 1 |
| Kester, AS; Mayfield, DC | 1 |
| Ferroni, R; Guggi, A; Rocchi, R; Tomatis, R | 1 |
| Careaga, CL; Falke, JJ | 1 |
| Bryant, DA; Golbeck, JH; Li, N; Warren, PV; Zhao, J | 1 |
| Akasaka, T; Ono, N; Sawai, T; Yamaguchi, A | 1 |
| Kirsch, JF; Toney, MD | 1 |
| Cuénod, M; Do, KQ; Gähwiler, BH; Jiang, ZP; Klancnik, JM | 1 |
| Damgaard, I; Dunlop, J; Grieve, A; Griffiths, R; Schousboe, A | 1 |
| Alexiev, U; Greenhalgh, DA; Heyn, MP; Khorana, HG; Otto, H; Subramaniam, S | 1 |
| Butler, MM; Graves, KL; Hardy, LW | 1 |
| Brass, A; Byers, PH; Grant, ME; Holmes, DF; Kadler, KE; Lightfoot, SJ | 1 |
| Cleland, WW; O'Leary, MH; Parmentier, LE; Schachman, HK | 1 |
| Altenbach, C; Greenhalgh, DA; Hubbell, WL; Khorana, HG | 1 |
| Koshland, DE; Lynch, BA | 1 |
| Attwell, D; Bouvier, M; Miller, BA; Szatkowski, M | 1 |
| Arakawa, T; Prestrelski, SJ | 1 |
| Fuchs, JA; Langsetmo, K; Woodward, C | 1 |
| Hardy, LW; Poteete, AR | 1 |
| Nekliudov, AD | 1 |
| Dunlop, J; Grieve, A; Griffiths, R; Schousboe, A | 1 |
| Takemoto, Y | 1 |
| Labruyere, J; Olney, JW; Price, MT; Zorumski, C | 1 |
| Eimerl, S; Minc-Golomb, D; Schramm, M | 1 |
| DuVal, G; Fowler, BA | 1 |
| Meessen, S; Oesterhelt, D; Otomo, J; Soppa, J; Straub, J; Tittor, J | 1 |
| Damgaard, I; Dunlop, J; Fosmark, H; Grieve, A; Griffiths, R; Schousboe, A | 1 |
| Carlson, HE; Miglietta, JT; Roginsky, MS; Stegink, LD | 1 |
| Bamforth, FJ; Graham, A; Kalsheker, NA; Markham, AF; Newton, CR; Powell, SJ | 1 |
| Mei, B; Zalkin, H | 1 |
| Giles, D; Usherwood, PN | 1 |
| Gray, PN; May, PC | 1 |
| Baba, A; Iwata, H; Morimoto, H | 1 |
| Erecińska, M; Troeger, MB | 1 |
| Thomson, AM | 1 |
| Bockaert, J; Pin, JP; Recasens, M | 1 |
| Pastuszko, A; Wilson, DF | 2 |
| Bockaert, J; Pin, JP; Recasens, M; Rumigny, JF | 1 |
| Baba, A; Iwata, H; Nishiuchi, Y; Tatsuno, T; Uemura, A | 1 |
| Cuénod, M; Do, KQ; Herrling, PL; Streit, P | 1 |
| Cullis, PM; Kleanthous, C; Lewendon, A; Murray, IA; Shaw, WV | 1 |
| Do, KQ; Herrling, PL; Turski, WA | 1 |
| Foote, J; Lauritzen, AM; Lipscomb, WN | 1 |
| Rubenstein, PA; Solomon, LR | 1 |
| Karlsson, JO; Sjöstrand, J | 1 |
| Chatagner, F; de Billy, G; Ipaktchi, M; Lefauconnier, JM; Portemer, C | 1 |
| Colman, RF | 1 |
| Tebecis, AK | 1 |
| Axelsson, H; Johansson, BG; Rymo, L | 1 |
| De Lorenzo, F; Givol, D | 1 |
| Hilschmann, N | 1 |
| Botes, DP | 1 |
| Cheah, KS; Watkins, JC | 1 |
| Fedorchenko, EIa; Petrun', LM | 1 |
| Benisek, WF | 1 |
| Ellison, JS; Siegel, L | 1 |
| Karadźić, V; Micić, D; Rakić, L | 1 |
| Haldeman, S; McLennan, H | 1 |
| Laycock, MV | 1 |
| Kvamme, E; Reichelt, KL | 1 |
| Coudert, M; Vandecasteele, JP | 1 |
| Crippa, PR; Tedeschi, RA; Vecli, A | 1 |
| Miyajima, R; Otsuka, S; Shiio, I | 1 |
| Bryan, JK | 1 |
| Litwack, G; Miller, JE | 1 |
| Read, CP; Southworth, GC | 1 |
| Andrews, AT | 1 |
| Kotyk, A; Ríhová, L | 1 |
| Biserte, G; Dautrevaux, M; Han, K | 1 |
| Cohen, GN; Falcoz-Kelly, F; Janin, J; Saari, JC; Truffa-Bachi, P; Véron, M | 1 |
| Miyamae, T | 1 |
| Bradbury, JH; Ley, KF | 1 |
| Morino, Y; Okamoto, M | 1 |
| Dembinski, A; Konturek, SJ; Radecki, T; Thor, P | 1 |
| Jenner, FA | 1 |
| Allen, G; Lowe, G | 1 |
| Cowman, RA; Fitzgerald, RJ; Perrella, MM | 1 |
| Kirschenbaum, DM | 1 |
| Bahadur, K; Singh, YP; Verma, ML | 1 |
| Read, CP; Ruff, MD | 1 |
| Kritchevsky, D; Story, JA; Tepper, SA | 1 |
| Chow, RB; Kassel, B | 1 |
| Lawrence, DA; Rowbury, RJ; Smith, DA | 1 |
| Borek, E; Hay, J; Pillinger, DJ | 1 |
| Kirschbaum, J; Ratych, OT; Wriston, JC | 1 |
| Gregory, H | 1 |
| Degani, Y; Patchornik, A; Spande, TF; Witkop, B | 1 |
| Staehelin, M; Wehrli, W | 1 |
| Hampton, JR | 1 |
| Smith, DA | 1 |
| Kotyk, A; Ponec, M; Ríhová, L | 1 |
| Kuo, SC; MacLeod, RA | 1 |
| Buu-Hoï, NP; Hauspie, R; Lambelin, G; Nicolle, J | 1 |
| Etzler, ME; Kabat, EA | 1 |
| Abel, CA; Grey, HM; Prahl, JW | 1 |
| Ghatak, UR; Kalita, C; Kovacs, J | 1 |
| Lazdunski, M; Vincent, JP | 1 |
| Garver, FA; Hilschmann, N | 1 |
| Knaape, HH; Wiechert, P | 1 |
| Husain, I; Norris, RF; Poupard, JA | 1 |
| De Marco, C; Rinaldi, A | 1 |
| Grossowicz, N; Lichtenstein, N; Schlesinger, M | 1 |
| Hornig, D; Weber, F; Wiss, O | 1 |
| Anthony, C; Drabble, WT; Robinson, JH | 1 |
| Markelova, SI; Zharikova, GG | 3 |
| Ho, OL; Olney, JW; Rhee, V | 1 |
| Gibbons, RJ; Loesche, WJ | 1 |
| Oppermann, W; Welge-Lüssen, L | 1 |
| Guest, JR; Yanofsky, C | 1 |
| Hock, A; Rüstow, B | 1 |
| Diven, WF; Johnston, MM | 1 |
| Hoshino, S; Tsubota, H | 1 |
| Duggan, AW; Johnston, GA | 1 |
| Haber, E; Waterfield, M | 1 |
| Ho, OL; Olney, JW | 1 |
| Neuhoff, V; Weise, M | 1 |
| Baranova, IP; Egorov, NS | 1 |
| Forget, P | 1 |
| Berry, K; Diamond, S; Hansen, S; Mok, C; Perry, TL | 1 |
| Dintzis, HM; McMenamy, RH; Watson, F | 1 |
| Kickuth, R; Scheffer, F; Schlimme, E | 1 |
| Ansorge, S; Bohley, P | 1 |
| Demeyer, DI; Henderickx, HK | 1 |
| King, KW; Rock, GC | 1 |
| Steenbergen, ST; Weinberg, ED | 1 |
| Meister, A; Tate, SS | 2 |
| Williams, VR; Wu, WT | 1 |
| McVeigh, I; Morton, K | 1 |
| Munier, RL; Sarrazin, G | 1 |
| Christian, JH; Waltho, JA | 1 |
| Ebata, M; Otsuka, H; Takahashi, Y | 1 |
| Elinov, NP; Kashkin, AP | 1 |
| Blum, JJ; Owens, I | 1 |
| Katorski, B; Zain-ul-Abedin, M | 1 |
| Meister, A; Miles, EW | 1 |
| Harper, E; Scharrer, B; Seifter, S | 1 |
| Carlisle, SA; Morse, GE; Willett, NP | 1 |
| Agnihotri, VP; Vaartaja, O | 1 |
| Bussolati, O; Christensen, HN; Dall'Asta, V; Gazzola, GC; Makowske, M | 1 |
| Baba, A; Iwata, H; Lee, E; Tatsuno, T | 1 |
| Lal, DN; Srivastava, AS | 1 |
| Mangano, RM; Schwarcz, R | 1 |
| Berthon, G; Germonneau, P | 1 |
| Donaldson, PL; Duce, IR; Usherwood, PN | 1 |
| Baba, A; Iwata, H; Kumagae, Y; Tatsuno, T | 1 |
| Buckthal, DJ; Burns, CL; Hamilton, GA; Main, DE | 1 |
| Donderski, W; Strzelczyk, E | 1 |
| Deschamps, A; Noel, C; Plichon, B | 1 |
| Chandra, H; Dixit, SN; Pandey, DK; Tripathi, NN | 1 |
| Dudley, RE; Klaassen, CD | 1 |
| Halász, P; Polgár, L | 1 |
| Lenney, JF | 1 |
| Baba, A; Iwata, H; Mizuo, H; Yamagami, S | 1 |
| Mostafa, SA | 1 |
| Jahoor, F; Jaksic, T; Miller, RG | 1 |
| Bryant, DA; Golbeck, JH; Jung, YS; Vassiliev, IR; Yu, L | 1 |
| Brennan, TV; Clarke, S | 1 |
| Futai, M; Iwamoto-Kihara, A; Jeanteur-De Beukelaer, C; Maeda, M; Omote, H | 1 |
| Chervitz, SA; Falke, JJ | 1 |
| Gerchman, Y; Olami, Y; Padan, E; Rimon, A; Schuldiner, S | 1 |
| Dobmeyer, J; Feussner, G; Lohrmann, J | 1 |
| Barbar, E; Fuchs, JA; Wilson, NA; Woodward, C | 1 |
| Chang, WI; Matthews, KS | 1 |
| Inagaki, Y; Kimura, T; Sawai, T; Yamaguchi, A | 1 |
| Herzberg, O; Liao, DI | 1 |
| Isoda, S; Ogasawara, Y; Tanabe, S | 1 |
| Fujii, J; Ikeda, Y; Meister, A; Taniguchi, N | 1 |
| Offer, G; Sessions, R | 1 |
| Scott, WG; Stoddard, BL | 1 |
| Cavenagh, M; Clark, J; Kahn, RA; Randazzo, PA; Rulka, C; Stearns, T; Terui, T; Zhang, CJ | 1 |
| Baumeister, W; Lupas, A; Seemüller, E; Zühl, F; Zwickl, P | 1 |
| Blumsom, NL; Gardiner, KA; Laming, PR | 1 |
| Hansen, L; Suzdak, PD; Thomsen, C | 1 |
| Aiach, M; Aillaud, MF; Alhenc-Gelas, M; Duchemin, J; Emmerich, J; Gandrille, S; Gaussem, P | 1 |
| Deutsch, JC; Hassell, KL; Kolhouse, JC; Kolhouse, JF; Santhosh-Kumar, CR | 1 |
| Nordlund, P; Ramponi, G; Stefani, M; Su, XD; Taddei, N | 1 |
| Anderson, KJ; Sandler, DL | 1 |
| Fuchs, JA; Hanson, C; Li, H; Thomas, GJ; Woodward, C | 1 |
| Murase, S; Yumoto, N | 1 |
| Bakker, A; Finkelstein, SD; Keller, G; Pricolo, VE; Przygodzki, R; Sayegh, R; Swalsky, PA | 1 |
| Fukazawa, C; Itoh, Y; Kadokawa, H; Kim, CS; Nong, VH; Totsuka, A | 1 |
| Beydon, D; Fabry, JP; Langonne, I; Payan, JP; Sabate, JP; Saillenfait, AM | 1 |
| Kimura, T; Sawai, T; Yamaguchi, A | 1 |
| Dunten, RL; Kaback, HR; Sahin-Tóth, M | 1 |
| Gomi, S; Imae, Y; Iwama, T; Lee, L | 1 |
| Dixon, JE; Fauman, EB; Saper, MA; Schubert, HL; Stuckey, JA | 1 |
| Dötsch, V; Oswald, RE; Wagner, G | 1 |
| Dencher, NA; Heberle, J; Oesterhelt, D; Riesle, J | 1 |
| Jahoor, F; Jaksic, T; Keshen, TH; Miller, RG; Shew, SB | 1 |
| Duncan, K; Kempsell, KE; Kim, DH; Lane, WS; Lees, WJ; Walsh, CT | 1 |
| Chiou, XG; DeFelippis, MR; Dennis, EA; Hyslop, PA; Kramer, RM; Pickard, RT; Reynolds, LJ; Sharp, JD; Strifler, BA; Tebbe, AL; Yee, YK | 1 |
| Kubo, K | 1 |
| Dekker, EE; Johnson, AR | 1 |
| Lawson, SL; Wakarchuk, WW; Withers, SG | 1 |
| Li, X; Orwar, O; Revesjö, C; Sandberg, M | 1 |
| Holkeri, H; Makarow, M; Pummi, T; Simonen, M; Vihinen, H | 1 |
| LeMaster, DM | 1 |
| Ikuta, K; Kameoka, M; Kimura, T; Okada, Y; Tobiume, M | 1 |
| Assmann, G; Bakker, HD; Bijvoet, SM; Bruin, T; Funke, H; Hayden, MR; Kastelein, JJ; Ma, Y; Reymer, PW; Wiebusch, H | 1 |
| Egashira, H; Fujii, I; Kanematsu, K; Okamura, M; Sagara, T; Shimohigashi, Y | 1 |
| Abbas, AK; Jardemark, K; Lehmann, A; Sandberg, M; Weber, SG | 1 |
| Cui, DS; Dyson, HJ; Holmgren, A; Jeng, MF; Kuprin, S; Lindell, M; Slaby, I; Tennant, LL | 1 |
| Hagberg, H; Puka-Sundvall, M; Sandberg, M | 1 |
| Fonnum, F; Mathisen, GA; Paulsen, RE | 1 |
| Beranová, S; Giorgianni, F; Viola, RE; Wesdemiotis, C | 1 |
| Armstrong, FA; Bartlett, BM; Breton, JL; Busch, JL; James, R; Thomson, AJ | 1 |
| Knappskog, PM; Martínez, A | 1 |
| Anthon, C; Degen, O; Eitinger, T; Wolfram, L | 1 |
| Acton, RT; Barton, JC; Harmon, L; Rivers, C; Rothenberg, BE; Sawada-Hirai, R; Shih, WW | 1 |
| Boehlein, SK; Schuster, SM; Walworth, ES | 1 |
| Mokhova, EN; Samartsev, VN | 1 |
| Aono, S; Bentrop, D; Bertini, I; Luchinat, C; Macinai, R | 1 |
| Bernard, A; Demuyter, P; Erbs, P; Jund, R | 1 |
| LeMaster, DM; Springer, PA; Unkefer, CJ | 1 |
| Cho, HS; Choi, G; Choi, KY; Joo, S; Kim, SW; Oh, BH | 1 |
| Mach, H; Middaugh, CR; Volkin, DB | 1 |
| Bass, RB; Danielson, MA; Falke, JJ | 1 |
| Kawabe, T; Kimura, T; Nakatani, M; Yamaguchi, A | 1 |
| Gottschalk, R; Hoelzer, D; Kaltwasser, JP; Löffler, T; Seidl, C; Seifried, E | 1 |
| Kolodziej, AF; Koshland, DE; Ottemann, KM; Shin, YK; Thorgeirsson, TE | 1 |
| McKay, DB; Wilbanks, SM | 1 |
| Grunewald, M; Kanner, BI; Kavanaugh, MP; Zarbiv, R | 1 |
| Kaback, HR; Sun, J; Venkatesan, P; Voss, J | 1 |
| Bourret, RB; Silversmith, RE | 1 |
| Brown, LS; Dioumaev, AK; Lanyi, JK; Needleman, R | 1 |
| Bashford, D; Dillet, V; Dyson, HJ | 1 |
| Alexiev, U; Behrens, W; Heyn, MP; Khorana, HG; Mollaaghababa, R | 1 |
| Butler, SL; Falke, JJ | 1 |
| Bach, JF; Boitard, C; Caillat-Zucman, S; Djilali-Saiah, I; Dubois-Laforgue, D; Larger, E; Mercadier, A; Timsit, J | 1 |
| Baiget, M; Barceló, MJ; Gimferrer, E | 1 |
| Armstrong, FA; Burgess, BK; Duff, JL; Gao-Sheridan, HS; Kemper, MA; Shen, B; Tilley, GJ | 1 |
| Bass, RB; Falke, JJ | 2 |
| Jung, H; Quick, M | 1 |
| Chen, YW; Dekker, EE; Johnson, AR | 1 |
| Anglade, P; Cenatiempo, Y; Dousset, X; Fremaux, C; Marlon, D; Metivier, A; Piard, JC; Pilet, MF; Sorokine, O; Zagorec, M | 1 |
| Halfon, S; Patel, S; Vega, F; Zurawski, G; Zurawski, S | 1 |
| Kashina, AS; Kwon, YT; Varshavsky, A | 1 |
| Inoue, T; Izui, K; Kai, Y; Kihara, A; Matsumura, H; Nagara, Y; Terada, K; Tsumura, K; Yoshinaga, T | 1 |
| Homma, H; Imai, K; Lee, JA; Nagata, Y | 1 |
| Anderson, GJ; Cullen, LM; Jazwinska, EC; Powell, LW; Ramm, GA | 1 |
| Alberts, IL; Nadassy, K; Wodak, SJ | 1 |
| Ganago, AO; Golbeck, JH; Jung, YS; McIntosh, L; Schulz, R; Vassiliev, IR; Yu, J | 1 |
| MacArthur, MW; Thornton, JM | 1 |
| Brown, LS; Lanyi, JK; Needleman, R; Váró, G | 1 |
| Ballesteros, JA; Chen, J; Chiappa, V; Javitch, JA; Simpson, MM | 1 |
| Bass, RB; Coleman, MD; Falke, JJ | 1 |
| French, GL; Shannon, KP; Stapleton, PD | 1 |
| Adams, MW; Brereton, PS; Duderstadt, RE; Johnson, MK; Staples, CR | 1 |
| Dawson, JH; Lu, Y; Pond, AE; Sigman, JA | 1 |
| Cheng, JY; Wallis, R | 1 |
| Duda, T; Koch, KW; Krishnan, A; Lange, C; Sharma, RK; Venkataraman, V | 1 |
| Hubbell, WL; Khorana, HG; Mollaaghababa, R; Steinhoff, HJ | 1 |
| Karlström, A; Rosenthal, K; Undén, A | 1 |
| Boitard, C; Caillat-Zucman, S; Dubois-Laforgue, D; Timsit, J | 1 |
| Dove, JE; Klinman, JP; Schwartz, B; Williams, NK | 1 |
| Caveney, S; Donly, C; Jevnikar, J; McLean, H | 1 |
| Kaback, HR; Sahin-Tóth, M | 1 |
| Amaya, Y; Amizuka, N; Fukushi-Irié, M; Ikehara, Y; Ito, M; Oda, K; Omura, S; Ozawa, H | 1 |
| Chidambaram, A; Fraser, MC; Goldstein, AM; Struewing, JP; Tucker, MA | 1 |
| Delgoda, R; Noble, ME; Sandy, J; Sim, E; Sinclair, JC | 1 |
| Balestrieri, C; Camardella, L; Carratore, V; Ciardiello, MA; Giovane, A; Servillo, L | 1 |
| Heise, CT; Leamy, CE; Nicholls, JR; Wallis, R | 1 |
| Ferry, JG; Tripp, BC | 1 |
| Eriguchi, Y; Haruta, S; Nukaga, M; O'Hara, K; Sawai, T; Yamaguchi, H; Yamamoto, ET | 1 |
| Martins, A; Shuman, S | 1 |
| Imanaga, I; Iwamoto, T; Shigekawa, M; Uehara, A | 1 |
| Crowder, MW; Taylor, RA; Yanchak, MP | 1 |
| Blackledge, MJ; Guilhaudis, L; Jacquot, JP; Krimm, I; Lancelin, JM; Marion, D | 1 |
| Allan, AM; Galindo, R; Paxton, LL; Queen, SA; Savage, DD | 1 |
| Klingler, KR; Wielckens, K; Zech, D | 1 |
| Parkin, G | 1 |
| Columbus, L; Hideg, K; Hubbell, WL; Jekö, J; Kálai, T | 1 |
| Brune, M; Corrie, JE; Webb, MR | 1 |
| Mushtaq, A; Payton, M; Sim, E; Sinclair, J; Wu, LJ; Yu, TW | 1 |
| Amrhein, N; Etezady-Esfarjani, T; Macheroux, P; Samland, AK | 1 |
| Calabrese, JC; Jordan, DB; Liao, DI; Viitanen, PV; Wawrzak, Z | 1 |
| Baasov, T; Golan, G; Shallom, D; Shoham, G; Shoham, Y; Shulami, S; Zaide, G; Zolotnitsky, G | 1 |
| Rana, TM; Shah, K; Wang, Z | 1 |
| Amarenco, P; Arveiler, D; Cambien, F; Elbaz, A; Evans, A; Gariepy, J; Grandchamp, B; Hetet, G; Kee, F; Morrison, C; Nicaud, V; Simon, A | 1 |
| Geczy, CL; Raftery, MJ; Valenzuela, SM; Yang, Z | 1 |
| Ahmadi, H; Croucher, MJ; Harris, JR; Lawrence, V; Thomas, LS | 1 |
| Moyer, RW; Shuman, S; Sriskanda, V | 1 |
| Bangera, MG; McGuire, KA; Olsen, JG; Siggaard-Andersen, M; von Wettstein-Knowles, P | 1 |
| Bocchi, EA; Cuoco, MA; da Silva, FF; Freitas, HF; Krieger, JE; Mansur, AJ; Mota, GF; Pereira, AC; Soler, JM | 1 |
| Caspar, DL; Guerrero, L; Logan, TM; Parthasarathy, G; Twigg, PD | 1 |
| Allen, JW; Aschner, M; Mutkus, LA; Shanker, G | 1 |
| Hayashi, H; Ikeda, R; Imaizumi, Y; Kawanaka, M; Sanae, F; Shiono, Y; Takikawa, T; Wakusawa, S; Yamada, G; Yano, M; Yoshioka, K | 1 |
| Kuroda, T; Matsuyama, SI; Terada, M; Tokuda, H | 1 |
| Anand, GS; Saxl, RL; Stock, AM | 1 |
| Blair, DF; Braun, TF | 1 |
| Beckman, L; Mikelsaar, AV; Pärlist, P; Tasa, G | 1 |
| Huang, DH; Kaylor, JJ; Malik, JJ; Risley, JM; Xia, YQ | 1 |
| Adachi, O; Devreese, B; Duine, JA; Hacisalihoglu, A; Hirotsu, K; Kim, JK; Kuroda, S; Miyahara, I; Okajima, T; Satoh, A; Tanizawa, K; Van Beeumen, J; Vandenberghe, I | 1 |
| Greven, H; Schmitt-Wrede, HP; Tschuschke, S; Wunderlich, F | 1 |
| Imoto, T; Ohkuri, T; Tsurumaru, M; Ueda, T | 1 |
| Pajor, AM; Yao, X | 1 |
| Jacobsen, MD; Jorgensen, PL; Pedersen, PA | 1 |
| Antonakis, K; Halmos, T; Le Breton, GC; Sullivan, NL; Turek, JW | 1 |
| Brothers, EN; Merz, KM; Suárez, D | 1 |
| Lukoyanov, DA; Scholes, CP; Shapleigh, JP; Toropov, YV; Wu, K; Zhao, Y | 1 |
| Beutler, E; Felitti, V; Gelbart, T; Ho, NJ; Waalen, J | 1 |
| An, JY; Davydov, IV; Du, F; Hu, RG; Kashina, AS; Kwon, YT; Seo, JW; Varshavsky, A | 1 |
| Cuthbertson, A; Husbyn, M | 1 |
| Kawate, H; Landis, DM; Loeb, LA | 1 |
| Kilberg, MS; Yang, W | 1 |
| Fukuda, A; Hara, T; Matsuyama, S; Nagasawa, H; Nakayama, J; Tokuda, H | 1 |
| Antony, J; Bauer, R; Gresh, N; Hemmingsen, L; Olsen, L; Schofield, CJ | 1 |
| Miziorko, HM; Runquist, JA | 1 |
| Ejima, D; Ishikawa, K; Kashiwagi, T; Matsui, H; Ono, K; Suzuki, E; Yokoyama, K | 1 |
| Barnes, S; Falany, CN; Sakalian, M; Sfakianos, MK; Wilson, L | 1 |
| Kantrowitz, ER; Tsuruta, H; West, JM | 1 |
| Abraham, EC; Bera, S; Cho, WJ; Thampi, P | 1 |
| Gronenborn, AM; Ishima, R; Louis, JM; Lynch, SM; Nesheiwat, I; Pannell, LK; Torchia, DA | 1 |
| Heikkinen, J; Luosujärvi, H; Myllylä, R; Risteli, M; Uitto, L; Wang, C | 1 |
| Smith, BJ | 1 |
| Galanko, J; Keku, T; Lawrence, LB; Martin, CF; Rohlfs, EM; Sandler, RS; Shaheen, NJ; Silverman, LM | 1 |
| Bognar, AL; Davidson, A; Ip, H; Liu, J; Sheng, Y | 1 |
| Agazie, YM; Hayman, MJ | 1 |
| Gross, AK; Oprian, DD; Xie, G | 1 |
| Chen, Y; Swanson, RA | 1 |
| Falke, JJ; Mehan, RS; White, NC | 1 |
| Cui, Q; Elstner, M; Frauenheim, T; Karplus, M; Kaxiras, E; Munih, P | 1 |
| Ikegami, K; Kim, H; Nakaoka, M; Sawa, Y; Shibata, H; Yagi, M | 1 |
| Bornemann, A; Dietzmann, K; Kirches, E; Mawrin, C; Meyermann, R; Müller, A; Pilz, P; Romeike, B; Scherlach, C; Schneider-Stock, R; Stoltenburg-Didinger, G; Van Landeghem, F; Von Deimling, A; Vorwerk, C; Wickboldt, J | 1 |
| Cram, ED; Crossley, M; Czolij, R; Mackay, JP; Matthews, JM; Simpson, RJ | 1 |
| Ascaso, C; Bruguera, M; Ingelmo, M; Oliva, R; Sánchez, M; Sanz, C; Villa, M | 1 |
| Jiang, M; Liu, J; Tseng, GN; Zhang, M | 1 |
| Carvajal, CA; Fardella, CE; Gomez-Sanchez, CE; González, A; Gonzalez, AA; Hevia, Mdel P; Lagos, ET; Montero, JA; Mosso, LM; Perez-Acle, TO; Romero, DG; Rosati, MP | 1 |
| Alexson, SE; Hunt, MC; O'Byrne, J; Rai, DK; Saeki, M | 1 |
| Harrison, NL; Jenkins, A; Schofield, CM | 1 |
| Li, RA; Tian, Y; Tomaselli, GF; Xiong, W | 1 |
| Anstrom, DM; Kallio, K; Remington, SJ | 1 |
| Hatanaka, A; Kimura, I; Kimura, M; Seki, N; Takeuchi, K; Yamada, S; Yamashita, S | 1 |
| BERGERET, B; CHATAGNER, F; FROMAGEOT, C | 1 |
| MARKO, AM | 1 |
| ARNOLD, WN; MORRIS, CJ; THOMPSON, JF | 1 |
| GOODER, H; MICHEL, MF | 1 |
| GULJAMOV, TD; KONIKOVA, AS; KRITZMAN, MG; POGOSOVA, AV; RAPOPORT, EA | 1 |
| MAKISUMI, S; NICHOLLS, CH; SAROFF, HA | 1 |
| DECONNINCK, G; VOETS, JP | 1 |
| DREL, KO | 1 |
| AGNIHOTRI, VP | 1 |
| LAVERACK, MS | 1 |
| SASAKI, T; SHIMURA, K; SUGAWARA, K | 1 |
| ZYGMUNT, WA | 1 |
| SELBIN, J; WILLIAMS, VR | 1 |
| FELDMAN, I; SAUNOR, P | 1 |
| MEISTER, A; NOVOGRODSKY, A; SODA, K | 1 |
| REINKING, A; STEYN PARVE, EP | 1 |
| BLAU, K; DARBRE, A | 1 |
| GERSCHENFELD, HM; LASANSKY, A | 1 |
| Bellamy, HD; Fox, RO; Kaluarachchi, WD; Liu, D; White, MA; Zhao, Y | 1 |
| Ketterman, AJ; Udomsinprasert, R; Wongtrakul, J | 1 |
| Angevine, CM; Fillingame, RH; Herold, KA | 1 |
| Jahng, WJ; Rando, RR; Xue, L | 1 |
| Rao, VB; Rentas, FJ | 1 |
| Dodson, ML; Lloyd, RS; Meador, MG; Rajagopalan, L | 1 |
| Bertoldi, M; Borri Voltattorni, C; Cellini, B | 1 |
| Himi, T; Ikeda, M; Morita, I; Nishida, M; Yasuhara, T | 1 |
| Chivers, PT; de Lamotte-Guery, F; Hirasawa, M; Jacquot, JP; Keryer, E; Kim, SK; Knaff, DB; Lemaire, SD; Longbine, CC; Mason, J; Miginiac-Maslow, M; Setterdahl, AT | 1 |
| Anselmi, L; Arrigoni, A; Bertario, L; Bonelli, L; Bruzzi, P; Fornasarig, M; Gentile, M; Gismondi, V; Mareni, C; Meta, M; Ponz de Leon, M; Radice, P; Sala, P; Varesco, L; Viel, A | 1 |
| Adachi, M; Furuchi, T; Homma, H; Imai, K; Koyama, H; Long, Z; Nakajima, T; Nimura, N; Sekine, M; Shimamoto, K | 1 |
| Bhogal, N; Blaney, FE; Findlay, JB; Ingley, PM; Rees, J | 1 |
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| Matsui, E; Matsui, I; Shen, Y; Tang, XF | 1 |
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| Bernard, MP; Cao, D; Lin, W; Moyle, WR; Myers, RV; Xing, Y | 1 |
| Kwak, EJ; Lim, SI | 1 |
| Holden, HM; Huang, X; Kim, J; Raushel, FM; Thoden, JB | 1 |
| Coulombe, RA; Rieben, WK | 1 |
| Jäschke, H; Kleinau, G; Krause, G; Lättig, J; Neumann, S; Paschke, R | 1 |
| Alvarez-Rúa, C; Karlsson, G; Maeder, D; Okvist, M; Robb, FT; Schwarz, F; Sjölin, L; Tigerström, A | 1 |
| Ginalski, K; Zemojtel, T | 1 |
| Asthagiri, D; Bashford, D; Liu, T; Noodleman, L; Van Etten, RL | 1 |
| Díez-Sampedro, A; Hirayama, BA; Loo, DD; Wright, EM; Zampighi, GA | 1 |
| Aronson, M; Cleary, SP; Cotterchio, M; Croitoru, ME; Di Nicola, N; Gallinger, S; Gryfe, R; Knight, J; Manno, M; Redston, M; Selander, T | 1 |
| Dávid, K; Horváth, G | 1 |
| Men, L; Wang, Y | 2 |
| Blanchetot, C; Chagnon, M; Dubé, N; Hallé, M; Tremblay, ML | 1 |
| Eapen, A; Sharma, A; Subbarao, SK | 1 |
| Davidson, VL; Jones, LH; Pearson, AR; Tang, Y; Wilmot, CM | 1 |
| Akerfeldt, KS; Cedervall, T; Halgand, F; Laprévote, O; Linse, S; Thulin, E; Vanbelle, C | 1 |
| Beck, SR; Bowden, DW; Burdon, KP; Freedman, BI; Langefeld, CD; Liu, Y; Rich, SS; Wagenknecht, LE | 1 |
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| Ivanenkov, VV; Kirley, TL; Meller, J | 1 |
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| Brown, MH; O'Rourke, BA; Skurray, RA; Xu, Z | 1 |
| Chi, CW; Jiang, H; Lu, W; Wang, CZ; Zhang, H; Zhao, ZQ | 1 |
| Chait, BT; Fushitani, K; Gorr, TA; Kao, WY; Knapp, JE; Qin, J; Riggs, AF; Riggs, CK; Smith, SS | 1 |
| Locas, CP; O'Brien, J; Wnorowski, A; Yaylayan, VA | 1 |
| Eliezer, D; Lu, M; Min, T; Wu, H | 1 |
| Hashimoto, M; Kihira, Y; Majima, E; Shinohara, Y; Terada, H | 1 |
| Abraham, SC; Adams, LA; Angulo, P; Brandhagen, D; Torgerson, H | 1 |
| Cahoon, RE; Jez, JM; Lang, A; Rea, PA; Rigden, DJ; Romanyuk, ND; Vatamaniuk, OK | 1 |
| Kim, J; Kornilova, AY; Laudon, H; Wolfe, MS | 1 |
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| Hu, CY; Hu, XQ; Zhang, HC | 1 |
| Graham, DE; Helgadóttir, S; Rosas-Sandoval, G; Söll, D | 1 |
| Iwatsubo, T; Morohashi, Y; Sato, C; Tomita, T | 1 |
| Gruschus, JM; Jeong, W; Lee, DY; Oho, T; Park, SJ; Rhee, SG; Sung, HJ; Wu, X | 1 |
| Angevine, CM; Fillingame, RH; Herold, KA; Vincent, OD | 1 |
| Fernandes, PA; Ramos, MJ; Sousa, SF | 1 |
| Cheng, HC; Gajewski, JE; Mulhern, TD; Nandurkar, H; Sio Seng Lio, D; Xiao, Y; Yeong Chit Chia, J; Zhu, HJ | 1 |
| Callender, R; Khajehpour, M; Liu, S; Wu, L; Zhadin, N; Zhang, ZY | 1 |
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| Ferguson, SJ; Mavridou, DA; Redfield, C; Stevens, JM | 1 |
| Angelogianni, P; Liapi, C; Schulpis, KH; Simintzi, I; Tsakiris, S | 2 |
| Betté, S; Castagna, M; Mandela, PG; Mari, SA; Peres, A; Rudnick, G; Sacchi, VF; Santacroce, M; Soragna, A | 1 |
| Barrett, R; Bush, RA; Dizhoor, AM; Fain, GL; Olshevskaya, EV; Peshenko, IV; Savchenko, AB; Sieving, PA; Woodruff, ML | 1 |
| Christensen, HE; Jensen, KP; Ooi, BL | 1 |
| Cantle, JP; Digruccio, MR; Fischer, WH; Grace, CR; Maji, SK; Manning, G; Perrin, MH; Riek, R; Smith, S; Vale, WW | 1 |
| Hotze, EM; Johnson, AE; Soltani, CE; Tweten, RK | 1 |
| Aoyama, K; Matsumura, N; Nakaki, T; Watabe, M | 1 |
| Basilico, F; Casadio, R; De Palma, A; Martelli, PL; Mauri, PL; Occhipinti, E; Sommaruga, S; Tortora, P; Trisciani, M | 1 |
| Brocklehurst, K; Gul, S; Hussain, S; Resmini, M; Thomas, EW; Thomas, MP; Verma, CS | 1 |
| Eliyahu, E; He, X; Park, JH; Schuchman, EH; Shalgi, R; Shtraizent, N | 1 |
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| Akiyama, T; Ikeda, D; Kajikawa, A; Nogawa, C; Samata, T; Sato, H; Yamada, D; Yamazaki, R | 1 |
| Bardien, S; Carr, J; Keyser, R; Lombard, D; Yako, Y | 1 |
| Castillo, E; Dwojak, S; Lagarias, JC; Njuguna, SL; Parson, VL; Roberts, L; Rockwell, NC; Spiller, SC | 1 |
| Iwatsubo, T; Sato, C; Takagi, S; Tomita, T | 1 |
| Bruysters, M; Themmen, AP; Verhoef-Post, M | 1 |
| Botzolakis, EJ; Lo, WY; Macdonald, RL; Tang, X | 1 |
| Chen, Y; Xing, G; Zhang, J; Zhao, Y | 1 |
| Chen, S; Hecht, SM | 1 |
| de Visser, SP; Straganz, GD | 1 |
| Ben-Yona, A; Kanner, BI | 1 |
| Oomens, J; Redlich, B; Steill, JD | 1 |
| Linder, ME; Nadolski, MJ | 1 |
| Fuchs, H; Jiang, L; Qing, G; Sun, T; Wang, X | 1 |
| Choi, KH; Fiebach, AR; Gottipati, K; Gut, M; Patel, P; Ramanujam, VM; Ruggli, N; Szymanski, MR; Tratschin, JD; Ye, M | 1 |
| Adolph, HW; Heinz, U; Hemmingsen, L; Kiefer, M | 1 |
| Chung, JW; Chung, SJ; Kim, M; Kim, UL; Lee, CS; Park, K; Yi, SY | 1 |
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| Kataoka, M; Matsuo, T; Otsuki, K; Shinohara, Y; Terada, H; Yamamoto, A; Yamamoto, T; Yamazaki, N | 1 |
| Boscherini, F; Cotton, NP; Francia, F; Giachini, L; Jackson, JB; Venturoli, G; Veronesi, G; Whitehead, SJ | 1 |
| Clarke, AJ; Cockburn, DW; Vandenende, C | 1 |
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| Baghel, GS; Dessingou, J; Mitra, A; Rao, CP; Tabbasum, K | 1 |
| Abdelmelek, MF; Blumenschein, GR; Byers, LA; Chen, L; Coombes, KR; Diao, L; Herbst, RS; Heymach, JV; Hong, WK; Ihle, NT; Kim, ES; Larsen, JE; Lee, JJ; Lippman, SM; Liu, S; Minna, JD; Papadimitrakopoulou, V; Powis, G; Saintigny, P; Tang, X; Tsao, A; Wang, J; Wistuba, II; Zhang, S | 1 |
| Ashida, H; Gohda, J; Inoue, J; Kim, M; Kobayashi, T; Koyama, T; Mimuro, H; Mizushima, T; Nagai, S; Ogawa, M; Oyama, A; Sanada, T; Sasakawa, C; Shibata, Y; Suzuki, M | 1 |
| Goldfarb, D; Gray, HB; Lancaster, KM; Potapov, A; Richards, JH | 1 |
| Mulligan, CN; Wang, S | 1 |
| Christensen, BM; Ding, H; Li, J; Liu, P | 1 |
| Fukumoto, M; Harada, S; Inagaki, K; Kudou, D; Murano, S; Sato, D; Shiba, T; Tamura, T | 1 |
| Fujii, N; Kita, A; Miki, K; Shimizu, K | 1 |
| Dessingou, J; Pathak, RK; Rao, CP | 1 |
| Deng, J; Mao, L; Qian, Q; Wang, D; Yang, L; Yu, P | 1 |
| Di Nardo, G; Gilardi, G; Giraudo, A; King, PW; Morra, S; Valetti, F | 1 |
| Bowie, JH; Calabrese, AN; Pukala, TL; Wang, T | 1 |
| Burckhardt, BC; Burckhardt, G; Hagos, Y | 1 |
| Anusiewicz, I; Sieradzan, I | 1 |
| Kimura, A; Kobayashi, M; Mori, H; Okuyama, M; Saburi, W | 1 |
| Ervasti, JM; Findlay, AR; Flanigan, KM; Howard, MT; Johnson, EK; Kaminoh, YJ; Maiti, B; Montanaro, F; Ray, WC; Simmons, TR; Strandjord, DM; Taylor, LE; Vulin, A; Wein, N | 1 |
| Qu, S; Zhang, X; Zhang, Y | 1 |
| Aliaga, AE; Campos-Vallette, MM; Cárcamo, JJ; Gómez-Jeria, JS; Kogan, MJ; Vera, AM | 1 |
| Capoferri, L; Lodola, A; Mor, M; Rivara, S | 1 |
| Akanuma, S; Hosoya, K; Kubo, Y; Zakoji, N | 1 |
| Gilmour, I; Olsson-Francis, K; Patel, MR; Ringrose, TJ; Rolfe, SM | 1 |
| Arendt, CS; Groll, M; Heinemeyer, W; Hochstrasser, M; Huber, EM; Li, X | 1 |
| Bergeron, A; Boivin, B; Gohla, A; Seifried, A | 1 |
| Ando, T; Ihara, K; Isogai, E; Katsube, S; Kim, S; Yoneyama, H | 1 |
| Amartely, H; Dvir, H; Kornitzer, D; Nasser, L; Pinsky, M; Weissman, Z | 1 |
| Albano, R; Lobner, D | 1 |
| Dong, L; Ling, B; Liu, Y; Zhao, C | 1 |
| Bankhele, P; Jamil, J; Njie-Mbye, F; Ohia, S; Opere, CA; Salvi, A | 1 |
| Amoresano, A; Avitabile, A; Cafaro, V; Di Donato, A; Di Maro, A; Izzo, V; Notomista, E; Pane, K; Pizzo, E; Rega, C; Varcamonti, M; Verrillo, M; Zanfardino, A | 1 |
| Lintuluoto, JM; Lintuluoto, M | 1 |
| Qu, S; Zhang, W; Zhang, X | 1 |
| Demura, M; Kamo, N; Kikukawa, T; Kimura-Someya, T; Miyauchi, S; Nara, T; Ohkawa, K; Ohsawa, N; Shimono, K; Shirouzu, M; Tamogami, J; Yokoyama, S | 1 |
| Bertamino, A; Campiglia, P; Carotenuto, A; Gomez-Monterrey, IM; Grieco, P; Novellino, E; Pepe, G; Sala, M; Scala, MC; Spensiero, A | 1 |
| Chen, H; Feng, Z; Leng, C; Liu, G; Lv, X; Qiao, Y; Sun, J; Zhang, Y | 1 |
| Shao, W; Wen, B; Xu, L; Yao, P; Zhang, Y; Zheng, W; Zhou, Z; Zhu, G | 1 |
| Coletti, C; Marrone, A; Re, N; Tolbatov, I | 1 |
| Mondal, S; Thompson, PR | 1 |
| Chen, H; Chen, J; Chen, X; Gu, Y; Huang, S; Wang, H; Wu, X; Xu, Y; Zhang, H; Zhang, Y | 1 |
| Ansari, MZ; Swaminathan, R | 1 |
| Du, Z; Mills, KV; Wang, C; Zhao, J | 1 |
| Liu, C; Miao, Y; Zhang, S; Zhang, X; Zhao, X | 1 |
| Chen, J; Duan, M; Duan, Y; Qi, Y; Yang, M | 1 |
| Cohen, EB; Geck, RC; Toker, A | 1 |
| Katsumi, H; Morishita, M; Moroto, Y; Nomura, D; Ogawa, K; Yamamoto, A | 1 |
| Abe, K; Hidaka, M; Kunii, K; Kurono, K; Miyamoto, A; Nanatani, K; Ogasawara, S; Suzuki, S; Yamanaka, T; Yoshimi, A | 1 |
| Au, WK; Cai, JP; Chai, Y; Chan, CC; Chan, JF; Chu, H; Foo, DC; Hou, Y; Hu, B; Huang, X; Jin, DY; Kok, KH; Lee, KS; Li, C; Luo, C; Poon, VK; Shi, J; Shuai, H; Sit, KY; Wang, Y; Wen, L; Wong, KK; Yang, D; Yoon, C; Yuan, S; Yuen, KY; Yuen, TT; Zhang, AJ; Zhao, X; Zhou, J | 1 |
| Abell, AD; Bruning, JB; Horsfall, AJ; Jovcevski, B; Klose, J; Pederick, JL; Pukala, TL | 1 |
| Chen, X; Ge, T; He, Z; Wang, J; Yuan, H; Zhang, L | 1 |
| Li, Z; Luo, Y; Ren, W; Teng, Y; Wang, H; Zhao, R | 1 |
| Chen, YY; Chou, YH; Liu, MN; Yang, BH; Yang, KC | 1 |
| Abe, K; Chiba, F; Kimura, T; Kon, N; Nanatani, K; Suzuki, S | 1 |
| Dietz, KJ; García-Caparrós, P; Kumar, V; Persicke, M; Vogelsang, L; Wirtz, M | 1 |
| Guo, W; Jia, M; Jiang, L; Jin, X; Kong, XY; Liu, B; Quan, D; Zhang, P; Zhang, Y; Zhang, Z; Zhou, M | 1 |
| Baysal, İ; Chankvetadze, B; Gumustas, M; Kale, NB; Kır, S; Nemutlu, E; Öztepe, T; Reçber, T; Yabanoğlu-Çiftçi, S | 1 |
| Li, Z; Lv, Y; Wang, G; Zhao, X; Zheng, Y | 1 |
| Carneiro, CEA; da Costa, ACS; Samulewski, RB; Tadayozzi, YS; Zaia, DAM | 1 |
| Che, L; Fang, Z; Feng, B; Hua, L; Jiang, X; Li, J; Lin, Y; Sun, M; Wang, Y; Xu, S; Zhuo, Y; Zou, X | 1 |
| Colacino, J; Elkin, ER; Harris, SM; Karnovsky, A; Loch-Caruso, RK; Su, AL | 1 |
| Asghari, G; Azizi, F; Bordbar, M; Hoseinpour, S; Mirmiran, P; Roosta, S; Sarbazi, N; Teymoori, F | 1 |
| Chang, CH; Chen, YL; Chen, YR; Cheng, KT; Efferth, T; Hung, SC; Lin, FW | 1 |
| Cheng, YT; Ding, YZ; Ji, LX; Ma, YZ; Meng, LQ; Xue, L; Zhu, T | 1 |
| Cao, B; Feng, WS; Hao, FX; Jiao, XM; Liang, XW; Zeng, MN; Zheng, XK | 1 |
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| Cha, SH; Chairoungdua, A; Endou, H; Kanai, Y; Kim, DK; Matsuo, H | 1 |
15 review(s) available for cysteine and aspartic acid
| Article | Year |
|---|---|
Amino acid biosynthesis and its regulation.
Topics: Amino Acids; Arginine; Aspartic Acid; Cysteine; Glutamates; Glutamine; Histidine; Phenylalanine; Pyruvates; Serine; Tyrosine | 1978 |
[Aliphatic alpha-amino acids as biologically active compounds].
Topics: Alanine; Amino Acids; Animals; Aspartic Acid; Cysteine; Glutamates; Glutamic Acid; Glycine; Homeostasis; Humans | 1990 |
Release of neuroactive substances: homocysteic acid as an endogenous agonist of the NMDA receptor.
Topics: Animals; Aspartic Acid; Brain; Chromatography, High Pressure Liquid; Cysteine; Homocysteine; N-Methylaspartate; Neurotransmitter Agents; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Tissue Distribution | 1988 |
[Chemical modifications of proteins: application to the study of their covalent structure (continuation and end)].
Topics: Aspartic Acid; Carbon Isotopes; Cysteine; Cystine; Electrophoresis, Paper; Lysine; Methionine; Methods; Peptides; Protein Conformation; Protein Hydrolysates; Proteins; Serine | 1972 |
Some polypeptides influencing gastric-acid secretion.
Topics: Amides; Animals; Aspartic Acid; Cattle; Chemical Phenomena; Chemistry; Cysteine; Dogs; Female; Gastric Juice; Gastrins; Gastrointestinal Hormones; Humans; Methionine; Peptides; Phenylalanine; Pregnancy; Propionates; Serine; Sheep; Swine; Tryptophan | 1970 |
Selective cleavage and modification of peptides and proteins.
Topics: Alanine; Aspartic Acid; Chemical Phenomena; Chemistry; Chymotrypsin; Cysteine; Glutamates; Glycine; Hydrogen-Ion Concentration; Methionine; Muramidase; Oxidation-Reduction; Peptides; Phenylalanine; Proline; Proteins; Pyrrolidines; Ribonucleases; Serine; Succinates; Threonine; Tryptophan | 1970 |
S-amino acid metabolism and its regulation in Escherichia coli and Salmonella typhimurium.
Topics: Amino Acids; Aspartic Acid; Chromosome Mapping; Chromosomes, Bacterial; Conjugation, Genetic; Cysteine; Escherichia coli; Feedback; Genes; Genes, Regulator; Homocysteine; Methionine; Methylation; Salmonella; Salmonella typhimurium; Serine; Sulfates; Transduction, Genetic | 1971 |
Current problems in mechanistic studies of serine and cysteine proteinases.
Topics: Aspartic Acid; Binding Sites; Catalysis; Cysteine; Cysteine Endopeptidases; Endopeptidases; Histidine; Models, Chemical; Papain; Protein Conformation; Serine Endopeptidases | 1982 |
Inhibitors associated with the proteinases of mammalian cells and tissues.
Topics: Animals; Aspartic Acid; Binding Sites; Cell Compartmentation; Cysteine; Hot Temperature; Humans; Kinetics; Lysosomes; Metals; Protease Inhibitors; Serine | 1980 |
Role of excitotoxins in developmental neuropathology.
Topics: Amino Acid Metabolism, Inborn Errors; Aspartic Acid; Brain Diseases; Brain Ischemia; Cloning, Molecular; Cysteine; Glutamates; Glycine; Humans; Oxidoreductases Acting on Sulfur Group Donors; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate | 1993 |
Degradative covalent reactions important to protein stability.
Topics: Aspartic Acid; Cysteine; Cystine; Disulfides; Hydrolysis; Methionine; Oxidation-Reduction; Proteins; Sulfhydryl Compounds | 1997 |
Genetics of hemochromatosis.
Topics: Amino Acid Substitution; Aspartic Acid; Cloning, Molecular; Cysteine; Genes, MHC Class I; Genes, Recessive; Hemochromatosis; Hemochromatosis Protein; Heterozygote; Histidine; Histocompatibility Antigens Class I; HLA Antigens; Homozygote; Humans; Iron; Membrane Proteins; Mutation, Missense; Tyrosine | 1999 |
Synthetic analogs of zinc enzymes.
Topics: Alcohol Dehydrogenase; Amidohydrolases; Amino Acid Motifs; Aminopeptidases; Animals; Aspartic Acid; Bacterial Proteins; Bicarbonates; Binding Sites; Carbonic Anhydrases; Carboxypeptidases; Catalysis; Cations, Divalent; Cysteine; Dihydroorotase; DNA Repair; Enzymes; Escherichia coli Proteins; Glutamic Acid; Histidine; Ligands; Liver; Matrix Metalloproteinases; Metalloproteins; Models, Chemical; Molecular Structure; N-Acetylmuramoyl-L-alanine Amidase; Nitrates; O(6)-Methylguanine-DNA Methyltransferase; Porphobilinogen Synthase; Spectrum Analysis; Thermolysin; Transcription Factors; Water; Zinc | 2001 |
[Iron storage disease].
Topics: Aspartic Acid; Carcinoma, Hepatocellular; Chromosomes, Human, Pair 6; Cysteine; Diabetes Mellitus; Diagnosis, Differential; Hemochromatosis; Histidine; Humans; Hyperpigmentation; Iron Overload; Liver Cirrhosis; Liver Neoplasms; Mass Screening; Phlebotomy; Point Mutation; Population Surveillance; Prevalence; Prognosis; Tyrosine | 2004 |
Excitatory neurotoxins as food additives: an evaluation of risk.
Topics: Adult; Age Factors; Aspartame; Aspartic Acid; Blood-Brain Barrier; Child; Cysteine; Dietary Supplements; Electrophysiology; Excitatory Amino Acids; Female; Food Analysis; Glutamic Acid; Humans; Neurotoxicity Syndromes; Neurotoxins; Pregnancy; Protein Hydrolysates; Risk Assessment; Risk Factors; Species Specificity | 1981 |
539 other study(ies) available for cysteine and aspartic acid
| Article | Year |
|---|---|
Catalytic properties of peptides with hydrolytic activity.
Topics: Aspartic Acid; Binding Sites; Catalysis; Cysteine; Esterases; Histidine; Hydrogen-Ion Concentration; Isoelectric Point; Oligopeptides; Sulfhydryl Compounds; Temperature | 1976 |
The anticlastogenic effect of various combinations of cysteamine, AET, HCT, and amino acids on chromosome damage by trenimon and bleomycin in human lymphocytes in vitro.
Topics: Alkylating Agents; Amino Acids, Sulfur; Aspartic Acid; beta-Aminoethyl Isothiourea; Bleomycin; Chromosome Aberrations; Chromosomes; Cysteamine; Cysteine; Lactones; Methionine; Mutagens; Serine; Triaziquone | 1978 |
The transport of L-cysteinesulfinate in rat liver mitochondria.
Topics: Animals; Aspartic Acid; Biological Transport; Cysteine; Enzyme Inhibitors; Glutamates; Kinetics; Malates; Mitochondria, Liver; Mitochondrial Swelling; Rats; Sulfinic Acids | 1979 |
Brain damage and oral intake of certain amino acids.
Topics: Administration, Oral; Age Factors; Animals; Aspartic Acid; Brain Damage, Chronic; Breast; Cysteine; Female; Glutamates; Guinea Pigs; Haplorhini; Humans; Hypothalamus; Infant Food; Maternal-Fetal Exchange; Mice; Milk, Human; Pregnancy; Rabbits; Rats | 1976 |
Specific cyanylation and cleavage at cysteine-104 human hemoglobin alpha-chain. A novel approach to the problem of the alpha-chain tryptic core in the study of haemoglobin variants by "fingerprinting" methods.
Topics: Alanine; Amino Acid Sequence; Aspartic Acid; Cyanides; Cysteine; Hemoglobins; Hemoglobins, Abnormal; Histidine; Humans; Hydrolysis; Pepsin A; Peptide Fragments; Protein Conformation; Trypsin | 1975 |
Cysteine sulfinic acid decarboxylase in rat brain: effect of vitamin B6 deficiency on soluble and particulate components.
Topics: Animals; Aspartic Acid; Brain; Carboxy-Lyases; Cysteine; Pyridoxal Phosphate; Pyridoxine; Rats; Sulfinic Acids; Time Factors; Vitamin B 6 Deficiency | 1975 |
Ligand-exchange chromatography of amino acids on copper-, cobalt- and zinc-chelex 100.
Topics: Amino Acids; Ammonia; Arginine; Aspartic Acid; Chromatography, Ion Exchange; Cobalt; Copper; Cysteine; Glutamates; Histidine; Ion Exchange Resins; Ligands; Lysine; Phenylalanine; Quaternary Ammonium Compounds; Serine; Threonine; Tyrosine; Zinc | 1975 |
Alteration of functional properties associated with the change in quaternary structure in unliganded haemoglobin.
Topics: Arginine; Aspartic Acid; Binding Sites; Cysteine; Hemoglobins; Histidine; Humans; Ligands; Oxygen; Oxyhemoglobins; Phytic Acid; Protein Conformation; Structure-Activity Relationship; Sulfhydryl Compounds; Tyrosine | 1975 |
Free amino acids of sex organs of the mouse: regulation by androgen.
Topics: Amino Acids; Aminobutyrates; Animals; Aspartic Acid; Castration; Cystathionine; Cysteic Acid; Cysteine; Cystine; Depression, Chemical; Epididymis; Ethanolamines; Glutamates; Glutathione; Glycerophosphates; Male; Mice; Proline; Prostate; Seminal Vesicles; Taurine; Testis; Testosterone; Tryptophan | 1975 |
Nutrition of Vitreoscilla stercoraria.
Topics: Alanine; Amino Acids; Aspartic Acid; Cysteine; Glutamates; Glutamine; Proline; Serine; Thiotrichaceae | 1975 |
Studies on trypsin inhibitors. Part III. Synthesis of the protected decapeptide (sequence 15-24) of porcine pancreatic secretory trypsin inhibitor II (Kazal).
Topics: Animals; Asparagine; Aspartic Acid; Cysteine; Glycine; Isoleucine; Peptides; Proline; Swine; Threonine; Trypsin Inhibitor, Kazal Pancreatic; Trypsin Inhibitors; Tyrosine; Valine | 1976 |
Structure and dynamics of Escherichia coli chemosensory receptors. Engineered sulfhydryl studies.
Topics: Aspartic Acid; Biophysical Phenomena; Biophysics; Cysteine; Escherichia coli; Galactose; Glucose; Molecular Structure; Mutagenesis, Site-Directed; Protein Conformation; Protein Engineering; Receptors, Amino Acid; Receptors, Cell Surface | 1992 |
Site-directed conversion of a cysteine to aspartate leads to the assembly of a [3Fe-4S] cluster in PsaC of photosystem I. The photoreduction of FA is independent of FB.
Topics: Aspartic Acid; Bacterial Proteins; Codon; Cyanobacteria; Cysteine; Electron Spin Resonance Spectroscopy; Electrons; Electrophoresis, Polyacrylamide Gel; Escherichia coli; Iron-Sulfur Proteins; Kinetics; Membrane Proteins; Mutagenesis, Site-Directed; Oxidation-Reduction; Photochemistry; Photosynthetic Reaction Center Complex Proteins; Photosystem I Protein Complex; Protein Conformation | 1992 |
Serine residues responsible for tetracycline transport are on a vertical stripe including Asp-84 on one side of transmembrane helix 3 in transposon Tn10-encoded tetracycline/H+ antiporter of Escherichia coli.
Topics: Alanine; Amino Acid Sequence; Antiporters; Aspartic Acid; Bacterial Proteins; Base Sequence; Biological Transport; Carrier Proteins; Cell Membrane; Cysteine; DNA Transposable Elements; DNA, Bacterial; Escherichia coli; Immunoblotting; Kinetics; Molecular Sequence Data; Mutagenesis, Site-Directed; Repressor Proteins; Serine; Tetracycline; Threonine | 1992 |
Brønsted analysis of aspartate aminotransferase via exogenous catalysis of reactions of an inactive mutant.
Topics: Acetates; Amines; Amino Acids; Aspartate Aminotransferases; Aspartic Acid; Catalysis; Cysteine; Formates; Hydrolysis; Lysine; Models, Chemical; Mutation; Neurotransmitter Agents; Oxaloacetates; Protons; Recombinant Proteins; Schiff Bases; Substrate Specificity | 1992 |
Release of endogenous amino acids, including homocysteic acid and cysteine sulphinic acid, from rat hippocampal slices evoked by electrical stimulation of Schaffer collateral-commissural fibres.
Topics: Amino Acids; Animals; Aspartic Acid; Cysteine; Electric Stimulation; Evoked Potentials; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Glycine; Hippocampus; Homocysteine; In Vitro Techniques; Kinetics; Male; Methionine; Nerve Fibers; Neurotransmitter Agents; Pyramidal Tracts; Rats; Rats, Inbred Strains; Time Factors | 1992 |
Sulphur-containing excitatory amino acid-evoked Ca(2+)-independent release of D-[3H]aspartate from cultured cerebellar granule cells: the role of glutamate receptor activation coupled to reversal of the acidic amino acid plasma membrane carrier.
Topics: Animals; Aspartic Acid; Calcium; Carrier Proteins; Cell Membrane; Cells, Cultured; Cerebellum; Cysteine; Glutamates; Homocysteine; Mice; Mice, Inbred Strains; Neurons; Neurotransmitter Agents; Quinoxalines; Rats; Rats, Wistar; Receptors, Glutamate; Synaptosomes; Tritium | 1992 |
Effect of introducing different carboxylate-containing side chains at position 85 on chromophore formation and proton transport in bacteriorhodopsin.
Topics: Amino Acid Sequence; Aspartic Acid; Bacteriorhodopsins; Cysteine; Glutamates; Glutamic Acid; Halobacterium salinarum; Iodoacetamide; Iodoacetates; Iodoacetic Acid; Kinetics; Mutagenesis, Site-Directed; Protons; Recombinant Proteins | 1992 |
Roles of Cys148 and Asp179 in catalysis by deoxycytidylate hydroxymethylase from bacteriophage T4 examined by site-directed mutagenesis.
Topics: Alleles; Amino Acid Sequence; Aspartic Acid; Bacteriophage T4; Cloning, Molecular; Cysteine; Deoxyuracil Nucleotides; Escherichia coli; Hydrogen Bonding; Hydroxymethyl and Formyl Transferases; Kinetics; Mutagenesis, Site-Directed; Recombinant Proteins; Transferases | 1992 |
Type I procollagens containing substitutions of aspartate, arginine, and cysteine for glycine in the pro alpha 1 (I) chain are cleaved slowly by N-proteinase, but only the cysteine substitution introduces a kink in the molecule.
Topics: Amino Acid Sequence; Arginine; Aspartic Acid; Cells, Cultured; Collagen; Cysteine; Electrophoresis, Polyacrylamide Gel; Fibroblasts; Glycine; Humans; Kinetics; Macromolecular Substances; Microscopy, Electron; Mutation; Osteogenesis Imperfecta; Pepsin A; Procollagen; Procollagen N-Endopeptidase; Protein Processing, Post-Translational; Protein Structure, Secondary; Skin; Substrate Specificity; Trypsin | 1992 |
13C isotope effects as a probe of the kinetic mechanism and allosteric properties of Escherichia coli aspartate transcarbamylase.
Topics: Adenosine Triphosphate; Allosteric Regulation; Aspartate Carbamoyltransferase; Aspartic Acid; Carbamyl Phosphate; Carbon Isotopes; Cysteine; Cytidine Triphosphate; Escherichia coli; Hydrogen-Ion Concentration; In Vitro Techniques; Kinetics; Macromolecular Substances; Neurotransmitter Agents | 1992 |
Locations of Arg-82, Asp-85, and Asp-96 in helix C of bacteriorhodopsin relative to the aqueous boundaries.
Topics: Amino Acid Sequence; Arginine; Aspartic Acid; Bacteriorhodopsins; Biological Transport, Active; Cysteine; DNA Mutational Analysis; Electron Spin Resonance Spectroscopy; Halobacterium; Lipids; Mesylates; Molecular Sequence Data; Protein Conformation; Spin Labels; Structure-Activity Relationship | 1991 |
Disulfide cross-linking studies of the transmembrane regions of the aspartate sensory receptor of Escherichia coli.
Topics: Amino Acid Sequence; Aspartic Acid; Cell Membrane; Chemotaxis; Cross-Linking Reagents; Cysteine; Disulfides; Escherichia coli; Models, Structural; Molecular Sequence Data; Mutagenesis, Site-Directed; Protein Conformation; Receptors, Amino Acid; Receptors, Cell Surface; S-Adenosylmethionine | 1991 |
Electrogenic uptake of sulphur-containing analogues of glutamate and aspartate by Müller cells from the salamander retina.
Topics: Amino Acids, Sulfur; Animals; Aspartic Acid; Cysteic Acid; Cysteine; Evoked Potentials; Glutamates; Homocysteine; Neurotoxins; Neurotransmitter Agents; Potassium; Retina; Sodium; Urodela | 1991 |
The solution structure and conformational dynamics of tumor necrosis factor-alpha and a (Cys69----Asp; Cys101----Arg) analog as examined by IR spectroscopy and hydrogen exchange.
Topics: Animals; Arginine; Aspartic Acid; Cysteine; Deuterium; Hydrogen; Mutagenesis, Site-Directed; Protein Conformation; Spectrophotometry, Infrared; Tumor Necrosis Factor-alpha | 1991 |
The conserved, buried aspartic acid in oxidized Escherichia coli thioredoxin has a pKa of 7.5. Its titration produces a related shift in global stability.
Topics: Alanine; Amino Acid Sequence; Aspartic Acid; Binding Sites; Buffers; Cysteine; Disulfides; Electrophoresis, Polyacrylamide Gel; Escherichia coli; Hydrogen-Ion Concentration; Models, Molecular; Molecular Sequence Data; Oxidation-Reduction; Proline; Protein Conformation; Sulfhydryl Compounds; Thioredoxins | 1991 |
Reexamination of the role of Asp20 in catalysis by bacteriophage T4 lysozyme.
Topics: Aspartic Acid; Base Sequence; Binding Sites; Catalysis; Cysteine; DNA Mutational Analysis; Genetic Complementation Test; Molecular Sequence Data; Muramidase; Recombinant Proteins; Salmonella Phages; Structure-Activity Relationship; T-Phages | 1991 |
Excitatory sulphur amino acids evoke a Ca2(+)-independent release of [3H]D-ASP and [3H]GABA from primary neuronal cultures by a mechanism which involves reversal of the high affinity transporters for L-glu and GABA, respectively.
Topics: Animals; Aspartic Acid; Calcium; Carrier Proteins; Cells, Cultured; Cysteine; GABA Plasma Membrane Transport Proteins; gamma-Aminobutyric Acid; Kinetics; Membrane Proteins; Membrane Transport Proteins; Monosaccharide Transport Proteins; Nerve Tissue Proteins; Neurons; Organic Anion Transporters | 1991 |
Amino acids with central pressor effect in conscious rats.
Topics: Amino Acids; Animals; Arginine; Asparagine; Aspartic Acid; Blood Pressure; Cysteine; Dose-Response Relationship, Drug; Heart Rate; Injections, Intravenous; Male; Pressoreceptors; Proline; Rats; Rats, Inbred Strains | 1990 |
L-cysteine, a bicarbonate-sensitive endogenous excitotoxin.
Topics: Animals; Animals, Newborn; Anticonvulsants; Aspartic Acid; Bicarbonates; Caudate Nucleus; Chick Embryo; Cysteine; Dibenzocycloheptenes; Dizocilpine Maleate; N-Methylaspartate; Necrosis; Neurons; Neurotoxins; Rats; Rats, Inbred Strains; Retina; Retinal Ganglion Cells; Zinc | 1990 |
Cysteine sulfinic acid-induced release of D-[3H]aspartate and [14C]GABA in hippocampus slices: the role of sodium channels and cAMP.
Topics: 1-Methyl-3-isobutylxanthine; Amino Acids; Animals; Aspartic Acid; Calcium; Cnidarian Venoms; Colforsin; Cysteine; gamma-Aminobutyric Acid; Hippocampus; In Vitro Techniques; Male; Neurotoxins; Neurotransmitter Agents; Rats; Sodium Channels; Tetrodotoxin | 1989 |
Preliminary purification and characterization studies of a low molecular weight, high affinity cytosolic lead-binding protein in rat brain.
Topics: Animals; Aspartic Acid; Blotting, Western; Brain Chemistry; Carrier Proteins; Chromatography, Gel; Chromatography, Ion Exchange; Cysteine; Cytosol; Electrophoresis, Polyacrylamide Gel; Glutamates; Glutamic Acid; Lead; Liver; Male; Molecular Weight; Rabbits; Rats; Rats, Inbred Strains | 1989 |
Bacteriorhodopsin mutants of Halobacterium sp. GRB. II. Characterization of mutants.
Topics: Amino Acid Sequence; Asparagine; Aspartic Acid; Bacteriorhodopsins; Base Sequence; Cloning, Molecular; Cysteine; Genes, Bacterial; Glutamates; Glutamic Acid; Glycine; Halobacterium; Molecular Sequence Data; Mutation; Protein Conformation; Tryptophan; Tyrosine | 1989 |
Inhibition by excitatory sulphur amino acids of the high-affinity L-glutamate transporter in synaptosomes and in primary cultures of cortical astrocytes and cerebellar neurons.
Topics: Amino Acids; Animals; Aspartic Acid; Astrocytes; Cerebellum; Cerebral Cortex; Cysteine; Glutamates; Glutamic Acid; Mice; Molecular Conformation; Neurotransmitter Uptake Inhibitors; Stereoisomerism; Synaptosomes | 1989 |
Stimulation of pituitary hormone secretion by neurotransmitter amino acids in humans.
Topics: Adrenocorticotropic Hormone; Adult; Amino Acids; Aspartic Acid; Cysteine; Female; Glutamates; Glutamic Acid; Growth Hormone; Humans; Hydrocortisone; Luteinizing Hormone; Male; Neurotransmitter Agents; Pituitary Gland; Pituitary Hormones; Prolactin; Taurine; Thyrotropin | 1989 |
Molecular characterisation of three alpha-1-antitrypsin deficiency variants: proteinase inhibitor (Pi) nullcardiff (Asp256----Val); PiMmalton (Phe51----deletion) and PiI (Arg39----Cys).
Topics: alpha 1-Antitrypsin; alpha 1-Antitrypsin Deficiency; Amino Acid Sequence; Arginine; Aspartic Acid; Base Sequence; Chromosome Deletion; Cysteine; Genes; Genetic Variation; Humans; Molecular Sequence Data; Oligonucleotide Probes; Phenylalanine; Valine | 1989 |
A cysteine-histidine-aspartate catalytic triad is involved in glutamine amide transfer function in purF-type glutamine amidotransferases.
Topics: Amino Acid Sequence; Anthranilate Synthase; Aspartic Acid; Binding Sites; Cysteine; Escherichia coli; Histidine; Molecular Sequence Data; Mutation; Nitrogenous Group Transferases; Transferases | 1989 |
The effects of putative amino acid neurotransmitters on somata isolated from neurons of the locust central nervous system.
Topics: Action Potentials; Animals; Aspartic Acid; Cysteine; Female; gamma-Aminobutyric Acid; Ganglia; Glutamates; Glutamic Acid; Grasshoppers; Ibotenic Acid; In Vitro Techniques; Kainic Acid; Membrane Potentials; Neurons; Neurotransmitter Agents; Taurine | 1985 |
L-Homocysteic acid as an alternative cytotoxin for studying glutamate-induced cellular degeneration of Huntington's disease and normal skin fibroblasts.
Topics: Aspartic Acid; Cell Survival; Cells, Cultured; Cysteic Acid; Cysteine; Fibroblasts; Glutamates; Glutamic Acid; Homocysteine; Humans; Huntington Disease; In Vitro Techniques; Isomerism; Kainic Acid; Kinetics; N-Methylaspartate; Neurotransmitter Agents; Skin; Time Factors | 1985 |
Neurochemical relation between excitatory and inhibitory amino acids in hippocampus.
Topics: Acetylcholine; Amino Acids; Animals; Aspartic Acid; Cysteine; gamma-Aminobutyric Acid; Hippocampus; In Vitro Techniques; Kainic Acid; Male; N-Methylaspartate; Neurons; Neurotransmitter Agents; Oxadiazoles; Potassium; Quisqualic Acid; Rats; Rats, Inbred Strains | 1985 |
Amino acid neurotransmitters in the CNS. Characteristics of the acidic amino acid exchange.
Topics: Amino Acids; Amino Acids, Sulfur; Animals; Aspartic Acid; Biological Transport; Brain Chemistry; Cysteic Acid; Cysteine; Glutamates; Glutamic Acid; Kinetics; Neurotransmitter Agents; Rats; Stimulation, Chemical; Synaptosomes | 1986 |
Comparison of responses to transmitter candidates at an N-methylaspartate receptor mediated synapse, in slices of rat cerebral cortex.
Topics: Amino Acids; Animals; Aspartic Acid; Cerebral Cortex; Cysteic Acid; Cysteine; Glutamates; Glutamic Acid; Magnesium; Male; N-Methylaspartate; Neurotransmitter Agents; Rats; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Synaptic Transmission | 1986 |
The binding of acidic amino acids to snail, Helix aspersa, periesophagic ring membranes reveals a single high-affinity glutamate/kainate site.
Topics: Amino Acids; Animals; Aspartic Acid; Binding Sites; Cysteine; Ganglia; Glutamates; Glutamic Acid; Helix, Snails; Hydrogen-Ion Concentration; In Vitro Techniques; Kainic Acid; Kinetics; Neurotransmitter Agents; Osmolar Concentration | 1986 |
Transport of cysteate by synaptosomes isolated from rat brain: evidence that it utilizes the same transporter as aspartate, glutamate, and cysteine sulfinate.
Topics: Amino Acids, Sulfur; Animals; Aspartic Acid; Binding, Competitive; Biological Transport; Brain; Carrier Proteins; Chromatography, High Pressure Liquid; Cysteic Acid; Cysteine; Glutamates; Glutamic Acid; Male; Neurotransmitter Agents; Potassium; Rats; Rats, Inbred Strains; Synaptosomes; Veratridine | 1986 |
Multiple Cl(-)-independent binding sites for the excitatory amino acids: glutamate, aspartate and cysteine sulfinate in rat brain membranes.
Topics: Animals; Aspartic Acid; Brain; Chlorides; Cysteine; Glutamates; Glutamic Acid; Kinetics; Male; Membranes; Neurotransmitter Agents; Rats; Rats, Inbred Strains; Sodium; Synaptic Membranes | 1987 |
Inhibition by forskolin of excitatory amino acid-induced accumulation of cyclic AMP in guinea pig hippocampal slices.
Topics: Adenosine; Amino Acids; Animals; Aspartic Acid; Chlorides; Colforsin; Cyclic AMP; Cysteine; Drug Interactions; Ethylmaleimide; Glutamates; Glutamic Acid; Guanosine Triphosphate; Guinea Pigs; Hippocampus; Histamine; Male; N-Methylaspartate; Neurotransmitter Agents; Veratridine | 1988 |
Amino acids modulate calcium permeability of the plasma membrane of human neuroblastoma cells.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Aspartic Acid; Calcium; Cell Membrane Permeability; Cysteine; Humans; Kainic Acid; N-Methylaspartate; Neuroblastoma; Neurotransmitter Agents; Tumor Cells, Cultured; Valine | 1988 |
Substitutions in the active site of chloramphenicol acetyltransferase: role of a conserved aspartate.
Topics: Alanine; Arginine; Asparagine; Aspartic Acid; Binding Sites; Chloramphenicol; Chloramphenicol O-Acetyltransferase; Cysteine; Drug Stability; Escherichia coli; Histidine; Hot Temperature; Hydrogen Bonding; Kinetics; Mutation; Structure-Activity Relationship; Sulfhydryl Reagents | 1988 |
Effects of L-cysteine-sulphinate and L-aspartate, mixed excitatory amino acid agonists, on the membrane potential of cat caudate neurons.
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; Amino Acids; Animals; Aspartic Acid; Cats; Caudate Nucleus; Cysteine; Female; Kainic Acid; Male; Membrane Potentials; N-Methylaspartate; Neurotransmitter Agents; Oxadiazoles; Quisqualic Acid | 1987 |
Substrate specificity of aspartate transcarbamylase. Interaction of the enzyme with analogs of aspartate and succinate.
Topics: Amino Acids; Aspartate Carbamoyltransferase; Aspartic Acid; Cysteine; Escherichia coli; Hydrogen-Ion Concentration; Kinetics; Neurotransmitter Agents; Substrate Specificity; Succinates; Succinic Acid | 1985 |
Correct NH2-terminal processing of cardiac muscle alpha-isoactin (class II) in a nonmuscle mouse cell.
Topics: Actins; Amino Acid Sequence; Animals; Aspartic Acid; Cell Line; Cysteine; Genes; Humans; L Cells; Methionine; Mice; Myocardium; Peptide Fragments; Protein Biosynthesis; Protein Processing, Post-Translational; Thermolysin; Trypsin | 1985 |
Axonal transport of proteins in retinal ganglion cells. Amino acid incorporation into rapidly transported proteins and distribution of radioactivity to the lateral geniculate body and the superior colliculus.
Topics: Alanine; Amino Acids; Animals; Aspartic Acid; Axonal Transport; Cysteine; Female; Geniculate Bodies; Glycine; Histidine; Leucine; Lysine; Male; Methionine; Nerve Tissue Proteins; Optic Nerve; Phenylalanine; Proline; Rabbits; Retina; Superior Colliculi; Tritium; Tryptophan | 1972 |
Redistribution of pyridoxal phosphate in the male rat liver as a result of repeated injections of hydrocortisone.
Topics: Alanine Transaminase; Animals; Aspartic Acid; Carboxy-Lyases; Cystathionine; Cysteine; Dose-Response Relationship, Drug; Homocysteine; Homoserine; Hydro-Lyases; Hydrocortisone; L-Serine Dehydratase; Liver; Lyases; Male; Pyridoxal Phosphate; Rats; Seasons; Serine; Time Factors; Tyrosine Transaminase | 1973 |
A glutamyl residue in the active site of triphosphopyridine nucleotide-dependent isocitrate dehydrogenase of pig heart.
Topics: Amides; Animals; Aspartic Acid; Binding Sites; Carbodiimides; Carbon Radioisotopes; Carboxy-Lyases; Catalysis; Cysteine; Drug Synergism; Glutamates; Glycine; Isocitrate Dehydrogenase; Isocitrates; Ketoglutaric Acids; Kinetics; Manganese; Morpholines; Myocardium; NADP; Swine; Temperature; Tyrosine | 1973 |
Studies on the identity of the optic nerve transmitter.
Topics: Acetylcholine; Acoustic Stimulation; Amino Acids; Aminobutyrates; Animals; Aspartic Acid; Auditory Cortex; Cats; Cysteine; Electric Stimulation; Ergothioneine; Geniculate Bodies; Glutamates; Homocysteine; Neural Pathways; Neurotransmitter Agents; Optic Nerve; Photic Stimulation; Serotonin; Synaptic Transmission; Visual Cortex | 1973 |
Isolation of immunoglobulin A (IgA) from human colostrum.
Topics: Alkylation; Amino Acids; Aspartic Acid; Buffers; Chromatography, Gel; Colostrum; Cysteine; Electrophoresis; Female; gamma-Globulins; Glutamates; Humans; Immunoelectrophoresis; Penicillamine; Pregnancy; Ultracentrifugation | 1966 |
The position of various cleavages of rabbit immunoglobulin G.
Topics: Amino Acid Sequence; Amino Acids; Animals; Aspartic Acid; Bromine; Carboxypeptidases; Chemical Phenomena; Chemistry; Chromatography, Gel; Cyanides; Cysteine; gamma-Globulins; Glutamates; Leucine; Lysine; Pepsin A; Proline; Rabbits; Serine; Sulfhydryl Compounds; Threonine; Trypsin | 1968 |
The chemical structure of immunoglobulins.
Topics: Amino Acid Sequence; Amino Acids; Antibodies; Antigens; Aspartic Acid; Bence Jones Protein; Chromatography; Countercurrent Distribution; Cysteine; gamma-Globulins; Haptens; Models, Chemical; Molecular Weight; Peptides | 1968 |
Snake venom toxins. The reactivity of the disulphide bonds of Naja nivea toxin alpha.
Topics: Animals; Aspartic Acid; Binding Sites; Biological Assay; Carbon Radioisotopes; Chromatography, Gel; Chromatography, Ion Exchange; Chromatography, Paper; Cysteine; Disulfides; Dithiothreitol; Electrophoresis, Paper; Glycine; Immunodiffusion; Iodoacetates; Lethal Dose 50; Mice; Peptide Fragments; Phenylalanine; Protein Binding; Protein Conformation; Snakes; Spectrophotometry, Ultraviolet; Toxins, Biological; Tryptophan; Venoms | 1974 |
Further syntheses in the study of structure-activity relationships of neuropharmacologically active amino acids.
Topics: Amino Alcohols; Animals; Aspartic Acid; Cats; Central Nervous System; Choline; Cysteine; Homocysteine; Muscle Spindles; Neurons; Serine; Sulfinic Acids | 1965 |
[Effect of Ni2+ ions on dephosphorylation of ATP and formation of aminoacyl phosphates by enzymes of rat liver microsomes in the presence of amino acids].
Topics: Adenosine Triphosphatases; Adenosine Triphosphate; Amino Acids; Animals; Aspartic Acid; Chlorides; Cysteine; Depression, Chemical; In Vitro Techniques; Membranes; Microsomes, Liver; Nickel; Phosphoric Acids; Rats; Serine; Stimulation, Chemical | 1969 |
Reaction of the catalytic subunit of Escherichia coli aspartate transcarbamylase with permanganate ion, a reactive structural analogue of phosphate ion.
Topics: Aspartic Acid; Binding Sites; Carbamates; Chemical Phenomena; Chemistry; Cysteine; Diphosphates; Escherichia coli; Mercaptoethanol; Oxidation-Reduction; Phosphates; Potassium Permanganate; Succinates; Sulfhydryl Compounds; Sulfhydryl Reagents; Sulfonic Acids; Transferases | 1971 |
Role of tyrosine in the substrate binding site of mitochondrial L-malate dehydrogenase from bovine heart muscle.
Topics: Acetates; Acylation; Animals; Aspartic Acid; Binding Sites; Carbon Isotopes; Carboxylic Acids; Catalysis; Cattle; Chemical Phenomena; Chemistry; Chlorides; Cysteine; Dicarboxylic Acids; Enzyme Activation; Fumarates; Glutamates; Hydrogen-Ion Concentration; Hydroxylamines; Imidazoles; Kinetics; Malate Dehydrogenase; Malates; Mercuribenzoates; Methane; Mitochondria, Muscle; Myocardium; NAD; Spectrophotometry; Sulfates; Sulfonic Acids; Tyrosine | 1971 |
Alterations of free amino acids concentrations in cat brain induced by rapid eye movement sleep deprivation.
Topics: Amino Acids; Aminobutyrates; Animals; Arginine; Aspartic Acid; Brain; Cats; Caudate Nucleus; Cysteine; Frontal Lobe; Glutamates; Glycine; Hippocampus; Histidine; Lysine; Male; Occipital Lobe; Reticular Formation; Serine; Sleep Deprivation; Sleep, REM; Thalamus; Threonine; Tyrosine | 1971 |
The antagonistic action of glutamic acid diethylester towards amino acid-induced and synaptic excitations of central neurones.
Topics: Action Potentials; Amino Acids; Animals; Aspartic Acid; Cats; Cysteine; Electric Stimulation; Esters; Excitatory Amino Acid Antagonists; Glutamates; Homocysteine; Interneurons; Iontophoresis; Medulla Oblongata; Methionine Sulfoximine; Spinal Cord; Synaptic Transmission; Thalamic Nuclei; Thalamus | 1972 |
The amino acid sequence of cytochrome c-553 from the Chrysophycean alga Monochrysis lutheri.
Topics: Amino Acid Sequence; Amino Acids; Animals; Asparagine; Aspartic Acid; Autoanalysis; Bacteria; Chymotrypsin; Cysteine; Cytochrome c Group; Dansyl Compounds; Electron Transport; Eukaryota; Glycine; Horses; Hydrolysis; Mitochondria, Muscle; Pepsin A; Peptides; Photosynthesis; Species Specificity; Thiocyanates; Time Factors; Trypsin | 1972 |
Histamine-dependent formation of N-acetyl-aspartyl peptides in mouse brain.
Topics: Acetates; Adenosine Triphosphate; Amino Acids; Animals; Aspartic Acid; Brain; Carbon Radioisotopes; Chromatography, Ion Exchange; Chromatography, Paper; Chromatography, Thin Layer; Cyclic AMP; Cysteine; Glutamates; Glycine; Histamine; Mice; Nialamide; Oligopeptides | 1973 |
[Obtaining regulation mutants from the biosynthesis pathway of lysine in a strain of Corynebacterium resistant to lysine analogues].
Topics: Aspartic Acid; Carbon; Corynebacterium; Cysteine; Hydro-Lyases; In Vitro Techniques; Lysine; Mutation; Nitrogen; Phosphotransferases; Picolinic Acids; Threonine | 1973 |
Radical yield in X-irradiated biological molecules. II. Naturally-occurring amino-acids.
Topics: Alanine; Amino Acids; Arginine; Asparagine; Aspartic Acid; Cysteine; Cystine; Electron Spin Resonance Spectroscopy; Free Radicals; Glutamates; Histamine; Isoleucine; Leucine; Lysine; Methionine; Phenylalanine; Proline; Radiation Effects; Serine; Threonine; Tryptophan; Tyrosine; Valine | 1974 |
Regulation of aspartate family amino acid biosynthesis in Brevibacterium flavum. I. Inhibition by amino acids of the enzymes in threonine biosynthesis.
Topics: Alanine; Alcohol Oxidoreductases; Amino Acids; Aspartate-Semialdehyde Dehydrogenase; Aspartic Acid; Brevibacterium; Cysteine; Glutathione; Isoleucine; Lyases; Lysine; Methionine; Phosphotransferases; Serine; Temperature; Threonine | 1968 |
Studies on the catalytic and regulatory properties of homoserine dehydrogenase of Zea mays roots.
Topics: Alcohol Oxidoreductases; Aminobutyrates; Aspartic Acid; Binding Sites; Cysteine; Hydroxybutyrates; Kinetics; NAD; NADP; Plants; Serine; Zea mays | 1969 |
Purification, properties, and identity of liver mitochondrial tyrosine aminotransferase.
Topics: Amino Acids; Animals; Antibodies; Asparagine; Aspartate Aminotransferases; Aspartic Acid; Chemical Phenomena; Chemistry, Physical; Chromatography, Gel; Crystallization; Cysteine; Cytoplasm; Diffusion; Dihydroxyphenylalanine; Fenclonine; Glutamates; Isoelectric Focusing; Isoenzymes; Ketoglutaric Acids; Male; Methionine; Mitochondria, Liver; Molecular Weight; Monoiodotyrosine; Oxaloacetates; Phenylpyruvic Acids; Rats; Stereoisomerism; Tryptophan; Tyrosine; Tyrosine Transaminase; Ultracentrifugation; Vibration | 1971 |
Absorption of some amino acids by the haemoflagellate, Trypanosoma gambiense.
Topics: Alanine; Amino Acids; Animals; Arginine; Aspartic Acid; Biological Transport; Carbon Isotopes; Cysteine; Glutamates; Glycine; Iodoacetates; Kinetics; Leucine; Lysine; Ornithine; Rats; Serine; Threonine; Trypanosoma brucei gambiense | 1972 |
Navy (Haricot)-bean (Phaseolus vulgaris) lectin. Isolation and characterization of tow components from a toxic agglutinating extract.
Topics: Alanine; Animals; Aspartic Acid; Chromatography, DEAE-Cellulose; Chromatography, Gel; Cysteine; Electrophoresis, Polyacrylamide Gel; Erythrocytes; Glucosamine; Glycoproteins; Hemagglutination Tests; Horses; Lectins; Leucine; Leukocytes; Mannose; Methionine; Molecular Weight; Plant Lectins; Plants; Quail; Serine; Tryptophan | 1974 |
Uptake of amino acids by actidione-treated yeast cells. IV. Interaction with sugars.
Topics: Amino Acids; Anaerobiosis; Aspartic Acid; Biological Transport, Active; Carbon Isotopes; Cycloheximide; Cysteine; Glycine; Leucine; Lysine; Methionine; Monosaccharides; Saccharomyces cerevisiae; Stereoisomerism | 1972 |
Revised structure of aspartokinase I-homoserine dehydrogenase I of Escherichia coli K12. Evidence for four identical subunits.
Topics: Alcohol Oxidoreductases; Amino Acid Sequence; Amino Acids; Aspartic Acid; Autoanalysis; Autoradiography; Chromatography, Gel; Chromatography, Ion Exchange; Cysteine; Electrophoresis, Polyacrylamide Gel; Escherichia coli; Homoserine; Isoelectric Focusing; Light; Macromolecular Substances; Molecular Weight; Peptides; Phosphotransferases; Scattering, Radiation; Sodium Dodecyl Sulfate; Spectrophotometry, Ultraviolet; Structure-Activity Relationship; Tryptophan | 1972 |
Studies on the growth conditions of Campylobacter fetus. II. The manifestation of nutritional requirements by conditional static cultivation.
Topics: Amino Acids; Aspartic Acid; Bacteriological Techniques; Campylobacter fetus; Cell Division; Culture Media; Cysteine; Growth Substances; Guanine; Nutritional Physiological Phenomena; Purines; Pyrimidines; RNA; Thioglycolates; Vitamins | 1974 |
The chemical composition of wool. XI. Separation and analysis of exocuticle and endocuticle.
Topics: Amino Acids; Animals; Aspartic Acid; Coloring Agents; Cysteine; Cystine; Formates; Histidine; Leucine; Lysine; Methionine; Microscopy, Electron; Phenylalanine; Proline; Pronase; Sheep; Structure-Activity Relationship; Threonine; Tyrosine; Wool | 1972 |
Affinity labeling of aspartate aminotransferase isozymes by bromopyruvate.
Topics: Animals; Aspartate Aminotransferases; Aspartic Acid; Binding Sites; Bromine; Carbon Isotopes; Chemical Phenomena; Chemistry; Circular Dichroism; Cysteine; Cytoplasm; Histidine; Hydrogen-Ion Concentration; Isoenzymes; Kinetics; Lysine; Mitochondria, Muscle; Myocardium; Peptides; Pyruvates; Spectrophotometry, Ultraviolet; Sulfinic Acids; Swine | 1973 |
Release of cholecystokinin by amino acids.
Topics: Alanine; Amino Acids; Animals; Aspartic Acid; Bicarbonates; Cholecystokinin; Cysteine; Dogs; Drug Synergism; Duodenum; Glutamates; Glycine; Intestinal Mucosa; Pancreas; Pancreatic Juice; Perfusion; Phenylalanine; Secretin; Threonine; Tryptophan | 1973 |
Medical research council unit for metabolic studies in psychiatry, Sheffield.
Topics: Amino Acid Metabolism, Inborn Errors; Aspartic Acid; Bipolar Disorder; Catatonia; Circadian Rhythm; Cysteine; Humans; Intellectual Disability; Lithium; Mass Spectrometry; Mental Disorders; Metabolism, Inborn Errors; Periodicity; Phenylketonurias; Sleep; Vasopressins | 1973 |
Investigation of the active site of papain with fluorescent probes.
Topics: Aspartic Acid; Binding Sites; Cysteine; Dioxins; Disulfides; Fluorescent Dyes; Histidine; Hydrogen-Ion Concentration; Nitro Compounds; Oxadiazoles; Papain; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet | 1973 |
Influence of incubation atmosphere on growth and amino acid requirements of Streptococcus mutans.
Topics: Amino Acids; Anaerobiosis; Antigens, Bacterial; Aspartic Acid; Cysteine; Glutamates; Oxygen; Serotyping; Streptococcus | 1974 |
Proteins lacking certain amino acids.
Topics: Arginine; Aspartic Acid; Cysteine; Glutamates; Histidine; Leucine; Lysine; Methionine; Peptides; Phenylalanine; Proteins; Tryptophan; Tyrosine; Valine | 1974 |
Effect of concentrations of ammonium molybdate, diammonium hydrogen phosphate, formaldehyde, and minerals in mixture on the synthesis of amino acids.
Topics: Alanine; Amino Acids; Arginine; Aspartic Acid; Chemical Phenomena; Chemistry; Chromatography, Paper; Colorimetry; Cysteine; Formaldehyde; Glycine; Histidine; Minerals; Molybdenum; Organophosphorus Compounds; Quaternary Ammonium Compounds; Sterilization; Sunlight; Tyrosine | 1974 |
Specificity of amino acid transport in Trypanosoma equiperdum.
Topics: Alanine; Amino Acids; Arginine; Aspartic Acid; Binding Sites; Biological Transport; Carbon Radioisotopes; Culture Media; Cysteine; Diffusion; Glucose; Glutamates; Histidine; Lysine; Phenylalanine; Stimulation, Chemical; Trypanosoma | 1974 |
Influence of synthetic conjugates of cholic acid on cholesteremia in rats.
Topics: Amidohydrolases; Animals; Aspartic Acid; Bile Acids and Salts; Cholanes; Cholesterol; Cholic Acids; Cysteine; Glutamates; Glycine; Glycocholic Acid; Hydrolysis; Intestines; Liver; Male; Organ Size; Rats; Structure-Activity Relationship; Taurocholic Acid | 1974 |
Bovine pepsinogen and pepsin. I. Isolation, purification, and some properties of the pepsinogen.
Topics: Abomasum; Amino Acids; Animals; Arginine; Aspartic Acid; Cattle; Chemical Precipitation; Chromatography, Gel; Chromatography, Ion Exchange; Cysteine; Electrophoresis, Disc; Enzyme Precursors; Glutamates; Glycine; Histidine; Isoleucine; Leucine; Lysine; Methionine; Molecular Weight; Pepsin A; Proline; Swine; Tryptophan; Ultracentrifugation | 1968 |
Regulation of the methionine-specific aspartokinase and homoserine dehydrogenase of Salmonella typhimurium.
Topics: Alcohol Oxidoreductases; Aspartic Acid; Cysteine; Feedback; Homocysteine; Methionine; Mutation; Phosphotransferases; Salmonella typhimurium | 1968 |
Effect of hypermethylation on the functional properties of transfer ribonucleic acid.
Topics: Alanine; Arginine; Aspartic Acid; Chemical Phenomena; Chemistry, Physical; Cysteine; Escherichia coli; Glutamine; Glycine; Histidine; Isoleucine; Kinetics; Leucine; Methylation; RNA, Bacterial; RNA, Transfer | 1969 |
Subunit structure of L-asparaginase from Escherichia coli B.
Topics: Antineoplastic Agents; Asparaginase; Asparagine; Aspartic Acid; Chemical Phenomena; Chemistry; Cysteine; Detergents; Electrophoresis; Escherichia coli; Ethanol; Formamides; Guanidines; Hydrogen-Ion Concentration; Lymphoma; Methods; Microscopy, Electron; Molecular Weight; Sodium Chloride; Sulfates; Ultracentrifugation; Urea | 1969 |
Fractionation of the nonpolar transfer ribonucleic acids from rat liver, yeast, and Escherichia coli by partition chromatography.
Topics: Amino Acid Sequence; Amino Acids; Animals; Arginine; Aspartic Acid; Chromatography; Chromatography, Gel; Cysteine; Escherichia coli; Genetic Code; Glutamates; Leucine; Liver; Lysine; Methionine; Nucleosides; Phenylalanine; Rats; RNA, Transfer; Saccharomyces; Serine; Species Specificity; Spectrophotometry; Tryptophan; Tyrosine; Ultraviolet Rays | 1971 |
Serine metabolism in the culture form of Trypanosoma cruzi: synthesis of other amino acids.
Topics: Alanine; Amino Acids; Animals; Aspartic Acid; Carbon Isotopes; Chromatography, Ion Exchange; Cysteine; Glutamates; Glycine; Protein Biosynthesis; Proteins; Serine; Threonine; Trypanosoma cruzi | 1971 |
Uptake of amino acids by actidione-treated yeast cells. I. Specificity of carriers.
Topics: Amino Acids; Arginine; Aspartic Acid; Binding Sites; Biological Transport; Carrier Proteins; Cell Membrane; Cycloheximide; Cysteine; Glutamates; Glycine; Histidine; Kinetics; Leucine; Lysine; Methionine; Proline; Protein Biosynthesis; Saccharomyces; Saccharomyces cerevisiae | 1971 |
Capacity of aspartic acid to increase the bacterial count on suspensions of Escherichia coli after freezing.
Topics: Acetates; Amino Acids; Aspartic Acid; Cysteine; Enterobacter; Escherichia coli; Freezing; Protein Hydrolysates; Pseudomonas; Pseudomonas aeruginosa; Serratia marcescens | 1969 |
[Effects of various amino acids on the sensitivity of 11 strains of Staphylococcus aureus to penicillin G].
Topics: Alanine; Amino Acids; Arginine; Asparagine; Aspartic Acid; Cysteine; Glycine; Isoleucine; Leucine; Methionine; Penicillin G; Penicillin Resistance; Staphylococcus; Stereoisomerism; Tryptophan; Valine | 1969 |
Purification and characterization of a lectin (plant hemagglutinin) with blood group A specificity from Dolichos biflorus.
Topics: ABO Blood-Group System; Adsorption; Amino Acids; Animals; Aspartic Acid; Binding Sites; Blood Group Antigens; Cysteine; Electrophoresis; Female; Hemagglutination Tests; Hexoses; Humans; Hydrogen-Ion Concentration; Immunodiffusion; Immunoelectrophoresis; Lectins; Methionine; Molecular Weight; Ovarian Cysts; Plant Lectins; Polysaccharides, Bacterial; Protein Binding; Rabbits; Seeds; Serine; Ultracentrifugation | 1970 |
Carboxy-terminal structure of the chain of human IgA myeloma proteins.
Topics: Alanine; Amino Acid Sequence; Amino Acids; Animals; Antigens; Aspartic Acid; Bence Jones Protein; Blood Protein Electrophoresis; Carboxypeptidases; Chemical Phenomena; Chemistry; Chromatography, Gel; Cyanides; Cysteine; Glutamates; Glycine; Humans; Immune Sera; Immunodiffusion; Immunoelectrophoresis; Immunoglobulin A; Immunoglobulin G; Iodine Isotopes; Methods; Models, Structural; Oxidation-Reduction; Peptides; Rabbits; Sulfides; Thiocyanates; Threonine; Tyrosine; Valine | 1971 |
Synthesis of polyglutathione, polyasparthione, and related sequential polypeptides.
Topics: Amino Acid Sequence; Aspartic Acid; Cysteine; Esters; Glutathione; Methods; Molecular Weight; Peptides; Radiation-Protective Agents; Structure-Activity Relationship | 1972 |
Trypsin-pancreatic trypsin inhibitor association. Dynamics of the interaction and role of disulfide bridges.
Topics: Acetamides; Alkylation; Aspartic Acid; Binding Sites; Borohydrides; Carbon Isotopes; Chromatography, Gel; Cysteine; Disulfides; Half-Life; Hydrogen-Ion Concentration; Imines; Iodoacetates; Kinetics; Lysine; Mathematics; Models, Chemical; Oxidation-Reduction; Pancreas; Protein Binding; Temperature; Trypsin; Trypsin Inhibitors; Trypsinogen | 1972 |
The primary structure of a monoclonal human lambda-type immunoglobulin L-chain of subgroup II (Bence-Jones protein NEI).
Topics: Amino Acid Sequence; Amino Acids; Aspartic Acid; Autoanalysis; Bence Jones Protein; Biological Evolution; Carbohydrates; Chromatography, DEAE-Cellulose; Chromatography, Gel; Chromatography, Ion Exchange; Chymotrypsin; Cysteine; Electrophoresis; Humans; Mutation; Plasmacytoma; Trypsin | 1972 |
[Experimental seizures caused by derivatives of glutamic acid].
Topics: Adipates; Amines; Aminocaproates; Animals; Aspartic Acid; Cats; Cysteine; Dogs; Female; Glutamates; Injections; Ketoglutaric Acids; Male; Pimelic Acids; Rats; Rats, Inbred Strains; Seizures; Succinates | 1972 |
Influence of nutrition on the morphology of a strain of Bifidobacterium bifidum.
Topics: Acetates; Alanine; Amino Acids; Asparagine; Aspartic Acid; Culture Media; Cysteine; Glutamates; Lactobacillus; Mutation; Nutritional Physiological Phenomena; Quaternary Ammonium Compounds; Serine; Surface-Active Agents; Tryptophan | 1972 |
Oxidative deamination of sulfonyl, sulfonyl and thiosulfonyl amino acids by D-aspartate oxidase.
Topics: Alanine; Amino Acid Oxidoreductases; Amino Acids; Animals; Aspartic Acid; Cattle; Cysteine; Deamination; Homocysteine; Kidney; Kinetics; Oxidation-Reduction; Oxygen Consumption; Pyruvates; Rabbits; Sulfinic Acids; Sulfonic Acids; Swine | 1972 |
Inhibition of murine tumors by carbobenzoxy derivatives of amino acids.
Topics: Amino Acids; Animals; Antineoplastic Agents; Asparagine; Aspartic Acid; Benzyl Compounds; Carcinoma, Ehrlich Tumor; Cysteine; Formates; Lymphoma, Non-Hodgkin; Mammary Neoplasms, Experimental; Mice; Neoplasms, Experimental; Phenylalanine | 1971 |
The effect of vitamin C depletion on the free amino acid content in blood plasma of the guinea pig.
Topics: Alanine; Amino Acids; Ammonia; Animals; Arginine; Ascorbic Acid Deficiency; Aspartic Acid; Citrulline; Cysteine; Glutamates; Glycine; Guinea Pigs; Histidine; Isoleucine; Lysine; Male; Methionine; Ornithine; Phenylalanine; Proline; Serine; Threonine; Time Factors; Tyrosine; Valine | 1971 |
Activity and regulation of an acidic amino acid permease of Aspergillus nidulans.
Topics: Ammonia; Asparagine; Aspartic Acid; Aspergillus; Cycloheximide; Cysteine; Glutamates; Glycine; Kinetics; Lysine; Membrane Transport Modulators; Membrane Transport Proteins; Methylamines; Nitrates; Urea | 1971 |
[Dissociation of S- and P-variants of Bacillus brevis var. G.-B. on a synthetic medium with amino acids as the only source of nitrogen].
Topics: Alanine; Amino Acids; Aspartic Acid; Bacillus; Culture Media; Cysteine; Genetic Variation; Glycine; Histidine; Leucine; Lysine; Mutation; Nitrogen; Ornithine; Phenylalanine; Serine; Stimulation, Chemical; Threonine; Time Factors; Tryptophan; Valine | 1971 |
Cytotoxic effects of acidic and sulphur containing amino acids on the infant mouse central nervous system.
Topics: Amino Acids; Animals; Aspartic Acid; Cysteine; Glutamine; Homocysteine; Hypothalamus; Mice; Microscopy, Electron; Retina | 1971 |
Amino acid fermentation by Fusobacterium nucleatum.
Topics: Amino Acids; Aspartic Acid; Cysteine; Fermentation; Fusobacterium; Gingiva; Glutamates; Glutamine; Histidine; Humans; Lysine; Methionine; Mouth; Serine; Threonine | 1968 |
[Amino acid determination in the aqueous humor and vitreous body of single eyes].
Topics: Alanine; Amino Acids; Animals; Aqueous Humor; Aspartic Acid; Chromatography, Ion Exchange; Cysteine; Glutamates; Glycine; Leucine; Phenylalanine; Rabbits; Taurine; Vitreous Body | 1969 |
Amino acid replacements associated with reversion and recombination within a coding unit.
Topics: Alanine; Amino Acids; Aspartic Acid; Cysteine; Escherichia coli; Genetic Code; Genetics; Glycine; In Vitro Techniques; Isoleucine; Ligases; Lysine; Mutation; Peptides; Serine; Tryptophan; Valine | 1965 |
[Quantitative evaluation of by paper and thin layer chromatographically separated amino acids with 1,3-dimethyl alloxan].
Topics: Alloxan; Amino Acids; Arginine; Aspartic Acid; Chromatography, Paper; Chromatography, Thin Layer; Cysteine; Drug Stability; Indicators and Reagents; Methionine; Methods; Peptides; Phenylalanine; Serine; Tryptophan | 1969 |
Studies on amino acid racemases. I. Partial purification and properties of the alanine racemase from Lactobacillus fermenti.
Topics: Acetates; Alanine; Aminobutyrates; Aspartic Acid; Centrifugation, Density Gradient; Chromatography, DEAE-Cellulose; Chromatography, Gel; Computers; Cysteine; Drug Stability; Glutamates; Glutathione; Hydrogen-Ion Concentration; Isomerases; Kinetics; Lactobacillus; Mercaptoethanol; Methods; Models, Biological; Models, Chemical; Pyridoxal Phosphate; Serine; Stereoisomerism; Temperature | 1969 |
Transaminase activity in sheep rumen content.
Topics: Alanine; Alanine Transaminase; Animals; Arginine; Aspartic Acid; Cysteine; Eukaryota; Glutamates; Hydrogen-Ion Concentration; Isoleucine; Leucine; Methionine; Phenylalanine; Rumen; Serine; Sheep; Temperature; Threonine; Tryptophan; Tyrosine; Valine | 1969 |
[Biosynthesis of gramicidin C on synthetic media with amino acids as the only N source].
Topics: Alanine; Amino Acids; Aspartic Acid; Bacillus; Culture Media; Cysteine; Glycine; Histidine; Hydrogen-Ion Concentration; Leucine; Lysine; Nitrogen; Ornithine; Phenylalanine; Serine; Threonine; Tryptophan; Tyrothricin; Valine | 1970 |
Glutamate and related amino acids in cat spinal roots, dorsal root ganglia and peripheral nerves.
Topics: Alanine; Amino Acids; Animals; Aspartic Acid; Cats; Cysteamine; Cysteine; Ganglia, Spinal; Glutamates; Glycine; Peripheral Nerves; Spinal Nerves | 1970 |
Amino acid sequence analysis with methyl isothiocyanate. Resolution of the methylthiohydantoins by gas-liquid partition chromatography.
Topics: Alanine; Amino Acid Sequence; Amino Acids; Animals; Aspartic Acid; Bence Jones Protein; Cattle; Chromatography, Gas; Cysteine; Dipeptides; Glutamates; Hydantoins; Indicators and Reagents; Insulin; Methods; Serine; Serum Albumin, Bovine; Solvents; Thiocyanates; Threonine | 1970 |
Brain damage in infant mice following oral intake of glutamate, aspartate or cysteine.
Topics: Administration, Oral; Animals; Animals, Newborn; Aspartic Acid; Cysteine; Flavoring Agents; Glutamates; Humans; Hypothalamus; Infant Nutritional Physiological Phenomena; Infant, Newborn; Mice; Retina | 1970 |
Determination of pico-mole quantities of gamma-amino-butyric acid (GABA) and serotonin.
Topics: Alanine; Amino Acids; Aminobutyrates; Animals; Arginine; Aspartic Acid; Autoradiography; Brain Chemistry; Carbon Isotopes; Cerebellum; Chromatography; Cysteine; Cystine; Glutamates; Glycine; Histidine; In Vitro Techniques; Isoleucine; Leucine; Lysine; Methods; Microchemistry; Phenylalanine; Proline; Radionuclide Imaging; Rats; Serine; Serotonin; Threonine; Tyrosine; Valine | 1970 |
[Effect of amino acids on the growth of Streptococcus lactis and biosynthesis of nisin].
Topics: Alanine; Amino Acids; Anti-Bacterial Agents; Arginine; Asparagine; Aspartic Acid; Culture Media; Cysteine; Cystine; Depression, Chemical; Glutamates; Glycine; Histidine; Leucine; Lysine; Methionine; Ornithine; Phenylalanine; Proline; Serine; Stimulation, Chemical; Streptococcus; Threonine; Tryptophan; Valine | 1970 |
[Bacterial nitrate reductases. Solubilization, purification and properties of the enzyme A of Micrococcus denitrificans].
Topics: Aspartic Acid; Chemical Phenomena; Chemistry; Cysteine | 1971 |
[Dissociation of R- and P plus-variants of Bacillus brevis var. G.-B. during growth on a synthetic medium with amino acids as the only source of nitrogen].
Topics: Alanine; Amino Acids; Aspartic Acid; Bacillus; Culture Media; Cysteine; Genetic Variation; Glycine; Histidine; Leucine; Lysine; Nitrogen; Ornithine; Phenylalanine; Serine; Threonine; Tryptophan; Valine | 1971 |
Regional distribution of amino acids in human brain obtained at autopsy.
Topics: Adult; Aged; Amino Acids; Amino Alcohols; Aminobutyrates; Aspartic Acid; Autopsy; Brain Chemistry; Chromatography, Paper; Cysteine; Dipeptides; Electrophoresis; Female; Glutamates; Glutathione; Glycerophosphates; Humans; Lysine; Male; Middle Aged; Phosphatidylethanolamines; Taurine | 1971 |
Cyanogen bromide fragments of human serum albumin.
Topics: Acetamides; Alanine; Amino Acids; Aspartic Acid; Chemical Phenomena; Chemical Precipitation; Chemistry; Chromatography, DEAE-Cellulose; Chromatography, Gel; Chromatography, Ion Exchange; Cyanides; Cysteine; Electrophoresis; Formates; Guanidines; Humans; Hydrogen-Ion Concentration; Iodoacetates; Leucine; Methods; Naphthalenes; Oxidation-Reduction; Peptides; Phenylalanine; Proline; Quaternary Ammonium Compounds; Serum Albumin; Sulfates; Sulfhydryl Reagents; Sulfonic Acids; Tetroses; Urea | 1971 |
[Biosphere products of Sinapis alba. I. Rhizosphere products].
Topics: Alanine; Amino Acids; Aminobutyrates; Arabinose; Arginine; Aspartic Acid; Citrates; Cysteine; Glucose; Glutamates; Glycine; Hexoses; Histidine; Keto Acids; Leucine; Mannose; Mustard Plant; Oxalates; Pentoses; Plants, Medicinal; Proline; Ribose; Threonine; Valine; Xylose | 1967 |
[Quantitative paper chromatography amino acid determination. Stanardization of the procedure and method of testing of new paper types].
Topics: Alanine; Amino Acids; Arginine; Aspartic Acid; Chromatography, Paper; Cysteine; Glutamates; Glycine; Histidine; Indicators and Reagents; Leucine; Lysine; Methionine; Methods; Paper; Phenylalanine; Serine; Spectrum Analysis; Sulfones; Threonine; Tyrosine; Ultraviolet Rays; Valine | 1967 |
Ammonia production by rumen microbes in vitro.
Topics: Alanine; Amino Acids; Ammonia; Animals; Arginine; Asparagine; Aspartic Acid; Cysteine; Glutamates; Glutamine; Glycine; Histidine; Hydrogen-Ion Concentration; Isoleucine; Leucine; Lysine; Methionine; Phenylalanine; Proline; Rumen; Serine; Threonine; Tryptophan; Tyrosine; Valine | 1967 |
Amino acid synthesis from glucose-U-14C in Argyrotaenia velutinana (Lepidoptera: Tortricidae) larvae.
Topics: Alanine; Amino Acids; Animals; Aspartic Acid; Autoanalysis; Carbon Isotopes; Colorimetry; Cysteine; Glucose; Glutamates; Glycine; Insecta | 1968 |
Trace metal requirements for malformin biosynthesis.
Topics: Alanine; Amino Acids; Anti-Bacterial Agents; Arginine; Aspartic Acid; Aspergillus; Chromium; Cobalt; Copper; Cysteine; Glutamine; Glycine; Histidine; Iron; Isoleucine; Leucine; Lysine; Manganese; Metals; Molybdenum; Peptide Biosynthesis; Phenylalanine; Plant Growth Regulators; Proline; Serine; Trace Elements; Tryptophan; Tyrosine; Valine; Zinc | 1968 |
Studies on the sulfhydryl groups of L-aspartate beta-decarboxylase.
Topics: Amines; Amino Acids; Aspartic Acid; Benzoates; Carbon Isotopes; Carboxy-Lyases; Chemical Phenomena; Chemistry; Cysteine; Electrophoresis; Mercury; Nitrogen; Pyridoxal Phosphate; Spectrum Analysis; Sulfhydryl Compounds; Transaminases | 1968 |
Subunit structure and isolation of a peptide containing the reactive cysteine group of beta-methylaspartase.
Topics: Amino Acids; Aspartic Acid; Binding Sites; Carbon Isotopes; Chromatography; Chromatography, Gel; Chromatography, Ion Exchange; Cysteine; Electrophoresis; Ethylmaleimide; Fumarates; Lyases; Peptides; Protein Hydrolysates; Sulfhydryl Compounds; Trypsin | 1968 |
The effects of various vitamin B6 5'-phosphate derivatives on the structure and activities of L-aspartate beta-decarboxylase.
Topics: Alanine; Alcaligenes; Amines; Aspartic Acid; Binding Sites; Carbon Isotopes; Carboxy-Lyases; Chemical Phenomena; Chemistry; Cysteine; Dialysis; Electrophoresis; Fluorometry; Hydrolases; Kinetics; Models, Chemical; Molecular Weight; Pyridoxal Phosphate; Pyridoxine; Pyruvates; Spectrum Analysis; Sulfur; Transaminases | 1969 |
Nutritional studies of Histoplasma capsulatum.
Topics: Asparagine; Aspartic Acid; Culture Media; Cysteine; Cystine; Glutamates; Glutathione; Histoplasma; Methionine; Proline; Thioglycolates; Vitamins | 1965 |
[Two dimension chromatography of ether soluble dinitrophenyl-amino acids and chromato-electrophoresis of hydracid-soluble DNP-amino acids on thin layers of powdered cellulose].
Topics: Arginine; Asparagine; Aspartic Acid; Cellulose; Chromatography, Thin Layer; Cysteine; Dinitrophenols; Electrophoresis; Glutamates; Glutamine; Histidine; Lysine | 1966 |
Water relations of Salmonella oranienburg; stimulation of respiration by amino acids.
Topics: Alanine; Asparagine; Aspartic Acid; Carbon Isotopes; Culture Media; Cysteine; Glucose; Glutamine; Glycine; Methionine; Oxygen Consumption; Proline; Salmonella; Serine; Threonine; Water | 1966 |
Analysis of N-methylamino acids by automatic amino acid analyzer and gas-liquid chromatography.
Topics: Alanine; Anti-Bacterial Agents; Arginine; Aspartic Acid; Autoanalysis; Chromatography, Gas; Cysteine; Cystine; Glutamates; Glycine; Indicators and Reagents; Isoleucine; Lysine; Phenylalanine; Serine; Threonine; Tyrosine; Valine | 1966 |
[Composition and properties of the preparations isolated from Act. coelicolor with the aid of beta-naphtol].
Topics: Acetates; Actinomyces; Alanine; Arginine; Aspartic Acid; Chromatography, Paper; Cysteine; Glucosamine; Glutamates; Glycerol; Leucine; Lysine; Naphthalenes; Peptides; Phosphates; Ribose; Serine; Valine | 1966 |
Amino acid esters as inhibitors of growth and of aminoacyl transfer ribonucleic acid synthetases in Euglena and Astasia.
Topics: Alanine; Amino Acids; Antimetabolites; Aspartic Acid; Cysteine; Esters; Euglena; Eukaryota; Glutamates; Hydrogen-Ion Concentration; Leucine; Ligases; Methionine; Phenylalanine; RNA, Transfer; Tryptophan; Tyrosine | 1967 |
Gluconeogenesis in the kidney and liver slices of a lizard, Uromastix hardwickii.
Topics: Animals; Aspartic Acid; Cysteine; Desert Climate; Gluconeogenesis; Glutamates; In Vitro Techniques; Kidney; Lactates; Liver; Proline; Reptiles; Succinates; Valine | 1967 |
The mechanism of the reaction of beta-hydroxyaspartate with L-aspartate beta-decarboxylase. A new type of pyridoxal 5'-phosphate-enzyme inhibition.
Topics: Alcaligenes; Aldehydes; Amino Acids; Aspartic Acid; Carbon Dioxide; Carbon Isotopes; Carboxy-Lyases; Chromatography, Gel; Cysteine; Enzymes; Hydrazones; Phenylhydrazines; Pyridoxal Phosphate; Serine; Spectrophotometry; Sulfinic Acids | 1967 |
Electron microscopic and biochemical characterization of collagen in blattarian insects.
Topics: Alanine; Ammonia; Animals; Arginine; Aspartic Acid; Collagen; Connective Tissue Cells; Cysteine; Cystine; Female; Glutamates; Glycine; Histidine; Histocytochemistry; Hydroxyproline; Insecta; Isoleucine; Leucine; Lysine; Male; Methionine; Microscopy, Electron; Phenylalanine; Proline; Serine; Threonine; Tyrosine; Valine | 1967 |
Requirements for growth of Streptococcus agalactiae in a chemically defined medium.
Topics: Alanine; Ascorbic Acid; Asparagine; Aspartic Acid; Culture Media; Cysteine; Cystine; Proline; Serine; Streptococcus; Thioglycolates | 1967 |
The influence of nitrogenous compounds on growth of Pythium species.
Topics: Alanine; Amino Acids; Aminobutyrates; Asparagine; Aspartic Acid; Cysteine; Fungi; Glutamates; Glycine; Histidine; Hydrogen-Ion Concentration; Nitrates; Nitrites; Nitrogen; Peptones; Quaternary Ammonium Compounds; Serine; Succinates; Threonine; Yeast, Dried | 1967 |
A stereoselective anomaly in dicarboxylic amino acid transport.
Topics: Amino Acids, Sulfur; Animals; Aspartic Acid; Biological Transport; Cells, Cultured; Cysteic Acid; Cysteine; Fibroblasts; Glutamates; Glutamic Acid; Humans; Hydrogen-Ion Concentration; Liver; Neurotransmitter Agents; Rats; Sodium; Stereoisomerism; Sulfinic Acids | 1981 |
Cysteine sulfinic acid in the central nervous system: antagonistic effect of taurine on cysteine sulfinic acid-stimulated formation of cyclic AMP in guinea pig hippocampal slices.
Topics: Animals; Aspartic Acid; Cerebral Cortex; Corpus Striatum; Cyclic AMP; Cysteine; Glutamates; Glutamic Acid; Guinea Pigs; Hippocampus; Male; Neurotransmitter Agents; Taurine | 1982 |
Effect of amino acids on microbial production of citric acid by Aspergillus niger.
Topics: Amino Acids; Aspartic Acid; Aspergillus niger; Citrates; Citric Acid; Cysteine; Glutamates; Glutamic Acid; Lysine; Serine | 1982 |
Chronic infusion of endogenous excitatory amino acids into rat striatum and hippocampus.
Topics: Animals; Aspartic Acid; Corpus Striatum; Cysteine; Glutamates; Glutamic Acid; Hippocampus; Male; Neurotransmitter Agents; Rats | 1983 |
Histamine as a ligand in blood plasma. Part 6. Aspartate and glutamate as possible partner ligands for zinc and histamine to favour histamine catabolism.
Topics: Aspartic Acid; Cysteine; Diffusion; Glutamates; Glutamic Acid; Histamine; Humans; Ligands; Zinc | 1982 |
Investigations into the mechanism of excitant amino acid cytotoxicity using a well-characterized glutamatergic system.
Topics: Animals; Aspartic Acid; Concanavalin A; Cysteine; Dose-Response Relationship, Drug; Glutamates; Glutamic Acid; Grasshoppers; Kainic Acid; Nerve Degeneration; Neuromuscular Junction; Neurotransmitter Agents; Oxadiazoles; Quisqualic Acid; Receptors, Cell Surface; Receptors, Glutamate; Synaptic Transmission | 1983 |
Modulation by bovine serum albumin of stimulated formation of cyclic AMP in guinea pig hippocampus.
Topics: Adenylyl Cyclases; Animals; Aspartic Acid; Cyclic AMP; Cysteine; Glutamates; Glutamic Acid; Guinea Pigs; Hippocampus; In Vitro Techniques; Male; Neurotransmitter Agents; Serum Albumin, Bovine | 1984 |
Thiazolidine-2-carboxylate derivatives formed from glyoxylate and L-cysteine or L-cysteinylglycine as possible physiological substrates for D-aspartate oxidase.
Topics: Amino Acid Oxidoreductases; Animals; Aspartic Acid; Cattle; Cysteine; D-Aspartate Oxidase; Dipeptides; Glutamates; Glutamic Acid; Glyoxylates; Hydrogen-Ion Concentration; Proline; Substrate Specificity; Thiazolidines | 1984 |
Manometric studies with bottom sediments of three lakes.
Topics: Aspartic Acid; Bacteria; Carbohydrate Metabolism; Cysteine; Fresh Water; Manometry; Oxygen Consumption; Poland; Tricarboxylic Acids; Water Microbiology | 1980 |
Transport of basic amino acids and regulation of aspartate kinase activity in thialysine and L-canavanine resistant strains of Serratia marcescens.
Topics: Amino Acids; Arginine; Aspartate Kinase; Aspartic Acid; Biological Transport; Canavanine; Cysteine; Drug Resistance, Microbial; Escherichia coli; Lysine; Phosphotransferases; Serratia marcescens | 1980 |
Antimycotic activity of some amino acids against dermatophytes.
Topics: Amino Acids; Antifungal Agents; Aspartic Acid; Cysteine; Microbial Sensitivity Tests; Microsporum; Trichophyton | 1984 |
Changes in hepatic glutathione concentration modify cadmium-induced hepatotoxicity.
Topics: Alanine; Animals; Aspartic Acid; Cadmium Poisoning; Chemical and Drug Induced Liver Injury; Cysteine; Drug Synergism; Glutathione; Ketones; L-Iditol 2-Dehydrogenase; Liver; Liver Diseases; Male; Maleates; Rats; Rats, Inbred Strains; Transaminases; Triglycerides | 1984 |
Cysteine sulfinic acid in the central nervous system: uptake and release of cysteine sulfinic acid by a rat brain preparation.
Topics: Animals; Aspartic Acid; Cerebral Cortex; Cysteine; Diazepam; Kinetics; Male; Neurotransmitter Agents; Potassium; Rats; Rats, Inbred Strains; Synaptosomes | 1982 |
Properties of L-asparaginase in cell-free extracts of Streptomyces karnatakensis.
Topics: Asparaginase; Aspartic Acid; Cysteine; Hydrogen-Ion Concentration; Kinetics; Potassium Cyanide; Stereoisomerism; Streptomyces; Temperature | 1982 |
[Relationship between cysteinesulfinate and aspartate transport in mitochondria].
Topics: Animals; Ascorbic Acid; Aspartic Acid; Biological Transport; Cysteine; Isomerism; Mitochondria, Liver; NADP; Neurotransmitter Agents; Oxidation-Reduction; Oxygen Consumption; Rats; Sulfinic Acids | 1980 |
Decreased cysteine and proline synthesis in parenterally fed, premature infants.
Topics: Alanine; Amino Acids; Aspartic Acid; Birth Weight; Blood Glucose; Carbon Isotopes; Cysteine; Electrolytes; Energy Intake; Female; Food, Formulated; Gas Chromatography-Mass Spectrometry; Gestational Age; Glucose; Glutamic Acid; Glycine; Humans; Infant Food; Infant Nutritional Physiological Phenomena; Infant, Newborn; Infant, Premature; Lipids; Male; Parenteral Nutrition; Parenteral Nutrition Solutions; Proline; Serine; Solutions | 1995 |
Modified ligands to FA and FB in photosystem I. II. Characterization of a mixed ligand [4Fe-4S] cluster in the C51D mutant of PsaC upon rebinding to P700-Fx cores.
Topics: Aspartic Acid; Chlorophyll; Cloning, Molecular; Cyanobacteria; Cysteine; Electron Spin Resonance Spectroscopy; Electron Transport; Escherichia coli; Freezing; Iron-Sulfur Proteins; Kinetics; Ligands; Macromolecular Substances; Membrane Proteins; Mutagenesis, Site-Directed; NADP; Oxidation-Reduction; Photochemistry; Photosystem I Protein Complex; Point Mutation; Proteins; Recombinant Proteins; Spectrophotometry; Thermodynamics; Time Factors | 1995 |
Effect of adjacent histidine and cysteine residues on the spontaneous degradation of asparaginyl- and aspartyl-containing peptides.
Topics: Adrenocorticotropic Hormone; Amides; Amino Acid Sequence; Amino Acids; Asparagine; Aspartic Acid; Cysteine; Histidine; Molecular Sequence Data; Oligopeptides; Stereoisomerism | 1995 |
Beta-gamma subunit interaction is required for catalysis by H(+)-ATPase (ATP synthase). Beta subunit amino acid replacements suppress a gamma subunit mutation having a long unrelated carboxyl terminus.
Topics: Amino Acid Sequence; Arginine; Aspartic Acid; Base Sequence; Binding Sites; Catalysis; Cysteine; DNA Primers; Escherichia coli; Frameshift Mutation; Glycine; Kinetics; Macromolecular Substances; Models, Structural; Molecular Sequence Data; Mutagenesis; Operon; Oxidative Phosphorylation; Plasmids; Point Mutation; Polymerase Chain Reaction; Protein Structure, Secondary; Proton-Translocating ATPases; Recombinant Proteins; Restriction Mapping | 1995 |
Lock on/off disulfides identify the transmembrane signaling helix of the aspartate receptor.
Topics: Amino Acid Sequence; Aspartic Acid; Cell Membrane; Chemotaxis; Cloning, Molecular; Cysteine; Disulfides; Histidine Kinase; Kinetics; Models, Structural; Mutagenesis, Site-Directed; Oxidation-Reduction; Phosphorylation; Point Mutation; Protein Conformation; Protein Engineering; Protein Kinases; Protein Structure, Secondary; Receptors, Amino Acid; Recombinant Proteins; Salmonella typhimurium; Signal Transduction | 1995 |
Replacements of histidine 226 of NhaA-Na+/H+ antiporter of Escherichia coli. Cysteine (H226C) or serine (H226S) retain both normal activity and pH sensitivity, aspartate (H226D) shifts the pH profile toward basic pH, and alanine (H226A) inactivates the ca
Topics: Alanine; Aspartic Acid; Codon; Cysteine; Escherichia coli; Histidine; Hydrogen-Ion Concentration; Mutagenesis, Site-Directed; Phenotype; Point Mutation; Serine; Sodium-Hydrogen Exchangers | 1995 |
Rapid and reliable identification of human apolipoprotein E1 (Gly127-->Asp, Arg158-->Cys) variant.
Topics: Apolipoproteins E; Arginine; Aspartic Acid; Cysteine; Glycine; Humans; Hyperlipoproteinemia Type III; Isoelectric Focusing; Mutation; Polymerase Chain Reaction | 1995 |
Aspartic acid 26 in reduced Escherichia coli thioredoxin has a pKa > 9.
Topics: Aspartic Acid; Binding Sites; Cysteine; Drug Stability; Escherichia coli; Hydrogen-Ion Concentration; Magnetic Resonance Spectroscopy; Models, Molecular; Molecular Structure; Oxidation-Reduction; Point Mutation; Protein Conformation; Thermodynamics; Thioredoxins | 1995 |
Role of Asp274 in lac repressor: diminished sugar binding and altered conformational effects in mutants.
Topics: Aspartic Acid; Binding Sites; Carbohydrate Metabolism; Cysteine; Escherichia coli; Ligands; Mutagenesis, Site-Directed; Point Mutation; Protein Conformation; Repressor Proteins; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet | 1995 |
Substrate-induced acceleration of N-ethylmaleimide reaction with the Cys-65 mutant of the transposon Tn10-encoded metal-tetracycline/H+ antiporter depends on the interaction of Asp-66 with the substrate.
Topics: Amino Acid Sequence; Antiporters; Aspartic Acid; Bacterial Proteins; Base Sequence; Cell Membrane; Cysteine; DNA Transposable Elements; Escherichia coli; Ethylmaleimide; Magnesium; Molecular Sequence Data; Mutagenesis, Site-Directed; NAD; Protein Conformation; Tetracycline | 1995 |
Refined structures of the active Ser83-->Cys and impaired Ser46-->Asp histidine-containing phosphocarrier proteins.
Topics: Aspartic Acid; Bacterial Proteins; Binding Sites; Crystallography, X-Ray; Cysteine; Mutation; Phosphoenolpyruvate Sugar Phosphotransferase System; Protein Conformation; Protein Folding; Serine | 1994 |
Tissue and subcellular distribution of bound and acid-labile sulfur, and the enzymic capacity for sulfide production in the rat.
Topics: Alkynes; Animals; Aspartic Acid; Chromatography, Gel; Cysteine; Cytosol; Glycine; Kidney; Liver; Male; Pargyline; Rats; Rats, Wistar; Subcellular Fractions; Sulfides; Sulfur; Tissue Distribution | 1994 |
Human gamma-glutamyl transpeptidase mutants involving conserved aspartate residues and the unique cysteine residue of the light subunit.
Topics: Aspartic Acid; Baculoviridae; Base Sequence; Binding Sites; Conserved Sequence; Cysteine; Escherichia coli; gamma-Glutamyltransferase; Glutamine; Hydrolysis; Kinetics; Models, Chemical; Molecular Sequence Data; Mutagenesis, Site-Directed; Recombinant Proteins; Structure-Activity Relationship | 1995 |
Computer modelling of the alpha-helical coiled coil: packing of side-chains in the inner core.
Topics: Alanine; Amino Acid Sequence; Arginine; Asparagine; Aspartic Acid; Computer Simulation; Cysteine; Glutamates; Glutamine; Histidine; Hydrogen Bonding; Isoleucine; Leucine; Lysine; Methionine; Models, Molecular; Molecular Sequence Data; Protein Structure, Secondary; Serine; Thermodynamics; Threonine; Tyrosine; Valine | 1995 |
Transmembrane signalling and the aspartate receptor.
Topics: Amino Acid Sequence; Aspartic Acid; Bacterial Physiological Phenomena; Binding Sites; Cell Membrane; Chemotaxis; Computer Graphics; Cross-Linking Reagents; Cysteine; Macromolecular Substances; Models, Molecular; Mutagenesis, Site-Directed; Protein Structure, Secondary; Receptors, Amino Acid; S-Adenosylmethionine; Signal Transduction; Software | 1994 |
Mutational analysis of Saccharomyces cerevisiae ARF1.
Topics: ADP-Ribosylation Factor 1; ADP-Ribosylation Factors; Alleles; Amino Acid Sequence; Aspartic Acid; Cysteine; DNA Mutational Analysis; Genes, Dominant; Genes, Lethal; GTP-Binding Proteins; Guanosine Triphosphate; Molecular Sequence Data; Point Mutation; Protein Binding; Saccharomyces cerevisiae | 1995 |
The proteasome from Thermoplasma acidophilum is neither a cysteine nor a serine protease.
Topics: Amino Acid Sequence; Animals; Aspartic Acid; Binding Sites; Cell Line, Transformed; Cysteine; Cysteine Endopeptidases; Histidine; Humans; Molecular Sequence Data; Multienzyme Complexes; Mutagenesis; Proteasome Endopeptidase Complex; Sequence Homology, Amino Acid; Serine Endopeptidases; Thermoplasma | 1995 |
Brain amino acid levels are related to seizure propensity in the gerbil (Meriones unguiculatus).
Topics: Amino Acids; Analysis of Variance; Animals; Arginine; Aspartic Acid; Behavior, Animal; Brain; Citrulline; Cysteine; Disease Susceptibility; Female; Gerbillinae; Glucose; Glutamates; Glutamic Acid; Glutamine; Glycine; Male; Seizures | 1993 |
L-glutamate uptake inhibitors may stimulate phosphoinositide hydrolysis in baby hamster kidney cells expressing mGluR1a via heteroexchange with L-glutamate without direct activation of mGluR1a.
Topics: Alanine Transaminase; Animals; Asparagine; Aspartic Acid; Cell Line; Cell Membrane; Cricetinae; Cycloleucine; Cysteine; Dicarboxylic Acids; Excitatory Amino Acid Antagonists; Glutamate Decarboxylase; Glutamic Acid; Hydrolysis; Kidney; N-Methylaspartate; Phosphatidylinositols; Pyrrolidines; Receptors, Metabotropic Glutamate | 1994 |
Influence of six mutations of the protein C gene on the Gla domain conformation and calcium affinity.
Topics: 1-Carboxyglutamic Acid; Adult; Amino Acid Sequence; Antibodies, Monoclonal; Arginine; Aspartic Acid; Calcium; Chromatography, Ion Exchange; Cysteine; Enzyme-Linked Immunosorbent Assay; Histidine; Humans; Male; Molecular Sequence Data; Mutation; Protein C; Protein Structure, Tertiary | 1994 |
Measurement of excitatory sulfur amino acids, cysteine sulfinic acid, cysteic acid, homocysteine sulfinic acid, and homocysteic acid in serum by stable isotope dilution gas chromatography-mass spectrometry and selected ion monitoring.
Topics: Aspartic Acid; Cysteic Acid; Cysteine; Deuterium; Gas Chromatography-Mass Spectrometry; Homocysteine; Humans; Isotope Labeling; Neurotransmitter Agents; Reference Values | 1994 |
The crystal structure of a low-molecular-weight phosphotyrosine protein phosphatase.
Topics: Animals; Aspartic Acid; Binding Sites; Catalysis; Cattle; Crystallography; Cysteine; Hydrogen Bonding; Models, Molecular; Molecular Weight; Protein Structure, Secondary; Protein Tyrosine Phosphatases | 1994 |
Autoradiography of L-[3H]aspartate binding sites.
Topics: Amino Acid Transport Systems; Animals; Aspartic Acid; Autoradiography; Binding Sites; Brain; Buffers; Carrier Proteins; Cysteic Acid; Cysteine; Glutamates; Glutamic Acid; Kinetics; Male; Neurotransmitter Agents; Rats; Rats, Sprague-Dawley; Receptors, Amino Acid; Sodium; Stereoisomerism; Tritium | 1993 |
Determination of the pKa values of active-center cysteines, cysteines-32 and -35, in Escherichia coli thioredoxin by Raman spectroscopy.
Topics: Amino Acid Sequence; Aspartic Acid; Chemical Phenomena; Chemistry, Physical; Cysteine; Escherichia coli; Glutamates; Glutamic Acid; Hydrogen Bonding; Hydrogen-Ion Concentration; Molecular Sequence Data; Protein Conformation; Protein Structure, Secondary; Solutions; Spectrum Analysis, Raman; Thioredoxins; Tryptophan; Tyrosine | 1993 |
Characterization of three types of aspartase activated by site-directed mutagenesis, limited proteolysis, and acetylation.
Topics: Acetic Anhydrides; Acetylation; Aspartate Ammonia-Lyase; Aspartic Acid; Chlorides; Cysteine; Enzyme Activation; Escherichia coli; Hydrogen-Ion Concentration; Kinetics; Mutagenesis, Site-Directed; Protein Conformation; Spectrophotometry, Ultraviolet; Trypsin | 1993 |
K-ras-2 topographic genotyping of pancreatic adenocarcinoma.
Topics: Adenocarcinoma; Alanine; Arginine; Aspartic Acid; Codon; Cysteine; DNA, Neoplasm; Exons; Forecasting; Genes, ras; Genotype; Glycine; Humans; Leucine; Mutation; Pancreas; Pancreatic Neoplasms; Serine; Survival Rate; Valine | 1994 |
Residues essential for catalytic activity of soybean beta-amylase.
Topics: Amino Acid Sequence; Aspartic Acid; Base Sequence; beta-Amylase; Binding Sites; Circular Dichroism; Cysteine; Electrophoresis, Polyacrylamide Gel; Glutamine; Glycine max; Hydrogen-Ion Concentration; Molecular Sequence Data; Mutagenesis, Site-Directed; Plasmids; Temperature | 1994 |
Specific amino acids modulate the embryotoxicity of nickel chloride and its transfer to the rat embryo in vitro.
Topics: Amino Acids; Animals; Aspartic Acid; Biological Transport; Cysteine; Embryo, Mammalian; Embryonic and Fetal Development; Female; Histidine; Nickel; Organ Culture Techniques; Pregnancy; Protein Binding; Rats; Rats, Sprague-Dawley; Tissue Distribution | 1993 |
Effects of sulfhydryl reagents on the Cys65 mutant of the transposon Tn10-encoded metal-tetracycline/H+ antiporter of Escherichia coli.
Topics: Amino Acid Sequence; Antiporters; Aspartic Acid; Bacterial Proteins; Carrier Proteins; Cysteine; DNA Transposable Elements; Escherichia coli; Ethylmaleimide; Methyl Methanesulfonate; Models, Molecular; Molecular Sequence Data; Mutation; Protein Conformation; Repressor Proteins; Structure-Activity Relationship; Sulfhydryl Reagents; Tetracycline; Tetracycline Resistance | 1993 |
Role of the charge pair aspartic acid-237-lysine-358 in the lactose permease of Escherichia coli.
Topics: Amino Acid Sequence; Aspartic Acid; Base Sequence; Biological Transport, Active; Cysteine; Electrochemistry; Enzyme Stability; Escherichia coli; Escherichia coli Proteins; Kinetics; Lactose; Lysine; Membrane Transport Modulators; Membrane Transport Proteins; Methylation; Molecular Sequence Data; Monosaccharide Transport Proteins; Mutagenesis, Site-Directed; Structure-Activity Relationship; Sulfhydryl Reagents; Symporters | 1993 |
Inhibition of aspartate chemotaxis of Escherichia coli by site-directed sulfhydryl modification of the receptor.
Topics: Aspartic Acid; Bacterial Proteins; Base Sequence; Chemoreceptor Cells; Chemotaxis; Cysteine; Dithionitrobenzoic Acid; Dithiothreitol; Escherichia coli; Escherichia coli Proteins; Membrane Proteins; Molecular Sequence Data; Mutagenesis, Site-Directed; Oligodeoxyribonucleotides; Receptors, Cell Surface; Sulfhydryl Compounds; Threonine | 1993 |
A ligand-induced conformational change in the Yersinia protein tyrosine phosphatase.
Topics: Amino Acid Sequence; Aspartic Acid; Binding Sites; Crystallization; Crystallography, X-Ray; Cysteine; Models, Molecular; Molecular Sequence Data; Mutation; Protein Conformation; Protein Tyrosine Phosphatases; Serine; Sulfates; Tungsten Compounds; Water; Yersinia | 1995 |
Amino-acid-type-selective triple-resonance experiments.
Topics: Alanine; Amino Acid Sequence; Amino Acids; Asparagine; Aspartic Acid; Calcium-Binding Proteins; Carbon; Carrier Proteins; Cysteine; Glycine; Image Enhancement; Isoleucine; Magnetic Resonance Spectroscopy; Methionine; Microfilament Proteins; Nitrogen; Serine; Valine | 1996 |
D38 is an essential part of the proton translocation pathway in bacteriorhodopsin.
Topics: Amino Acid Sequence; Aspartic Acid; Bacteriorhodopsins; Cysteine; Glutamic Acid; Halobacterium; Hydrogen-Ion Concentration; Kinetics; Light; Models, Structural; Mutagenesis, Site-Directed; Point Mutation; Protein Structure, Secondary; Recombinant Proteins; Spectrophotometry; Spectroscopy, Fourier Transform Infrared | 1996 |
Compartmentation of endogenously synthesized amino acids in neonates.
Topics: Amino Acids; Analysis of Variance; Apolipoprotein B-100; Apolipoproteins B; Aspartic Acid; Blood Glucose; Carbon Isotopes; Cysteine; Fibrinogen; Gas Chromatography-Mass Spectrometry; Gestational Age; Glucose; Humans; Infant, Newborn; Infant, Premature; Liver; Parenteral Nutrition; Proline; Protein Binding | 1996 |
Characterization of a Cys115 to Asp substitution in the Escherichia coli cell wall biosynthetic enzyme UDP-GlcNAc enolpyruvyl transferase (MurA) that confers resistance to inactivation by the antibiotic fosfomycin.
Topics: Alkyl and Aryl Transferases; Anti-Bacterial Agents; Aspartic Acid; Catalysis; Cell Wall; Cysteine; Drug Resistance, Microbial; Escherichia coli; Fosfomycin; Kinetics; Mutagenesis, Site-Directed; Thermodynamics; Transferases | 1996 |
Identification of essential residues for the catalytic function of 85-kDa cytosolic phospholipase A2. Probing the role of histidine, aspartic acid, cysteine, and arginine.
Topics: Amino Acid Sequence; Amino Acids; Arginine; Aspartic Acid; Biological Evolution; Catalysis; Conserved Sequence; Cysteine; Histidine; Molecular Sequence Data; Mutagenesis, Site-Directed; Phospholipases A; Phospholipases A2; Sequence Homology, Amino Acid | 1996 |
Variability in heat-induced fragmentation of a protein in the presence of dodecyl sulfate: the role of an intramolecular sulfhydryl/disulfide exchange.
Topics: alpha-Amylases; Amino Acid Sequence; Aspartic Acid; Aspergillus oryzae; Cysteine; Disulfides; Dithionitrobenzoic Acid; Electrophoresis, Polyacrylamide Gel; Hot Temperature; Kinetics; Oxidation-Reduction; Peptide Fragments; Protein Denaturation; Proteins; Sodium Dodecyl Sulfate; Sulfhydryl Compounds; Thermodynamics | 1995 |
Woodward's reagent K inactivation of Escherichia coli L-threonine dehydrogenase: increased absorbance at 340-350 nm is due to modification of cysteine and histidine residues, not aspartate or glutamate carboxyl groups.
Topics: Alcohol Oxidoreductases; Amino Acid Sequence; Aspartic Acid; Bacterial Proteins; Cysteine; Enzyme Inhibitors; Escherichia coli; Glutamic Acid; Histidine; Isoxazoles; Kinetics; Models, Chemical; Molecular Sequence Data; Solvents; Spectrophotometry, Ultraviolet; Sulfhydryl Compounds | 1996 |
Effects of both shortening and lengthening the active site nucleophile of Bacillus circulans xylanase on catalytic activity.
Topics: Amino Acid Sequence; Aspartic Acid; Bacillus; Base Sequence; Binding Sites; Carbohydrate Conformation; Carbohydrate Sequence; Catalysis; Cysteine; Glutamic Acid; Glycoside Hydrolases; Glycosylation; Iodoacetates; Iodoacetic Acid; Kinetics; Mass Spectrometry; Molecular Sequence Data; Mutagenesis, Site-Directed; Oligodeoxyribonucleotides; Point Mutation; Xylan Endo-1,3-beta-Xylosidase; Xylosidases | 1996 |
Gamma-glutamyl peptides and related amino acids in rat hippocampus in vitro: effect of depolarization and gamma-glutamyl transpeptidase inhibition.
Topics: Amino Acids; Animals; Aspartic Acid; Cysteine; Dipeptides; Enzyme Inhibitors; Female; gamma-Glutamyltransferase; Glutamates; Glutamic Acid; Glutamine; Glutathione; Hippocampus; Isoxazoles; Male; Rats; Rats, Sprague-Dawley | 1996 |
Glycosylation of rat NGF receptor ectodomain in the yeast Saccharomyces cerevisiae.
Topics: Amino Acid Sequence; Animals; Aspartic Acid; Autoradiography; Base Sequence; Blotting, Western; Cloning, Molecular; Cysteine; Electrophoresis, Polyacrylamide Gel; Escherichia coli; Glycoproteins; Glycosylation; Heat-Shock Proteins; Mannose; Methionine; Molecular Sequence Data; Oligodeoxyribonucleotides; Protein Conformation; Rats; Receptors, Nerve Growth Factor; Recombinant Fusion Proteins; Recombinant Proteins; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Sulfur Radioisotopes; Tritium | 1996 |
Structural determinants of the catalytic reactivity of the buried cysteine of Escherichia coli thioredoxin.
Topics: Aspartic Acid; Binding Sites; Catalysis; Cysteine; Electrochemistry; Escherichia coli; Hydrogen-Ion Concentration; Magnetic Resonance Spectroscopy; Structure-Activity Relationship; Thioredoxins; Titrimetry | 1996 |
Intracellular glutathione as a possible direct blocker of HIV type 1 reverse transcription.
Topics: Acetylcysteine; Aspartic Acid; Cysteine; Dithiothreitol; DNA, Viral; Glutathione; HIV Reverse Transcriptase; HIV-1; Humans; Transcription, Genetic; Tumor Cells, Cultured | 1996 |
Compound heterozygosity for a known and a novel defect in the lipoprotein lipase gene (Asp250-->Asn; Ser251-->Cys) resulting in lipoprotein lipase (LPL) deficiency.
Topics: Adolescent; Asparagine; Aspartic Acid; Cysteine; Denmark; DNA; Heterozygote; Humans; Hyperlipoproteinemia Type I; Hypertriglyceridemia; Lipoprotein Lipase; Male; Mutagenesis, Site-Directed; Point Mutation; Polymerase Chain Reaction; Serine | 1996 |
Ligand recognition in mu opioid receptor: experimentally based modeling of mu opioid receptor binding sites and their testing by ligand docking.
Topics: Affinity Labels; Amino Acid Sequence; Animals; Aspartic Acid; Binding Sites; Brain; Computer Simulation; Conserved Sequence; Cysteine; Dihydromorphine; Guinea Pigs; Ileum; Ligands; Male; Models, Chemical; Models, Molecular; Molecular Sequence Data; Protein Conformation; Receptors, Opioid, mu; Sequence Homology, Amino Acid | 1996 |
Bicarbonate-sensitive cysteine induced elevation of extracellular aspartate and glutamate in rat hippocampus in vitro.
Topics: Animals; Aspartic Acid; Bicarbonates; Cysteine; Cystine; Extracellular Space; gamma-Aminobutyric Acid; Glutamic Acid; Hippocampus; In Vitro Techniques; Neurotransmitter Agents; Rats; Taurine | 1997 |
Effects of buried charged groups on cysteine thiol ionization and reactivity in Escherichia coli thioredoxin: structural and functional characterization of mutants of Asp 26 and Lys 57.
Topics: Amino Acid Sequence; Aspartic Acid; Bacteriophage T7; Cysteine; Escherichia coli; Hydrogen-Ion Concentration; Lysine; Magnetic Resonance Spectroscopy; Mutagenesis, Site-Directed; Oxidation-Reduction; Solubility; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet; Structure-Activity Relationship; Sulfhydryl Compounds; Thioredoxin-Disulfide Reductase; Thioredoxins; Titrimetry; Tryptophan; Viral Proteins | 1997 |
Brain injury after hypoxia-ischemia in newborn rats: relationship to extracellular levels of excitatory amino acids and cysteine.
Topics: Analysis of Variance; Animals; Animals, Newborn; Aspartic Acid; Brain; Brain Injuries; Carotid Artery, Common; Cysteine; Excitatory Amino Acids; Extracellular Space; Factor Analysis, Statistical; Female; Glutamic Acid; Hypoxia, Brain; Ischemic Attack, Transient; Male; Microdialysis; Rats; Rats, Wistar; Reperfusion; Statistics, Nonparametric | 1997 |
Contributing mechanisms for cysteine excitotoxicity in cultured cerebellar granule cells.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Aspartic Acid; Bicarbonates; Biological Transport; Cell Death; Cells, Cultured; Cerebellum; Culture Media; Cysteine; Dithiothreitol; Dizocilpine Maleate; Glutamic Acid; Hydrogen-Ion Concentration; Kinetics; Magnesium; Neurons; Neurotoxins; Rats; Rats, Wistar | 1996 |
Mapping the mechanism-based modification sites in L-aspartase from Escherichia coli.
Topics: Aspartate Ammonia-Lyase; Aspartic Acid; Bacterial Proteins; Chromatography, High Pressure Liquid; Cysteine; Deamination; Enzyme Inhibitors; Escherichia coli; Fumarates; Lysine; Mutagenesis, Site-Directed; Peptide Fragments | 1997 |
[3Fe-4S] <--> [4Fe-4S] cluster interconversion in Desulfovibrio africanus ferredoxin III: properties of an Asp14 --> Cys mutant.
Topics: Amino Acid Sequence; Aspartic Acid; Cysteine; Desulfovibrio; Dithionite; Electrochemistry; Electron Spin Resonance Spectroscopy; Electrophoresis, Polyacrylamide Gel; Ferredoxins; Iron; Molecular Sequence Data; Mutagenesis; Restriction Mapping; Spectrophotometry, Ultraviolet; Sulfur | 1997 |
Effect of mutations at Cys237 on the activation state and activity of human phenylalanine hydroxylase.
Topics: Aspartic Acid; Chemical Phenomena; Chemistry, Physical; Cysteine; Enzyme Activation; Enzyme Stability; Humans; Hydrogen-Ion Concentration; Kinetics; Mutagenesis, Site-Directed; Phenylalanine Hydroxylase; Serine; Spectrometry, Fluorescence | 1997 |
A Ni2+ binding motif is the basis of high affinity transport of the Alcaligenes eutrophus nickel permease.
Topics: Alcaligenes; Alkaline Phosphatase; Amino Acid Sequence; Antiporters; Aspartic Acid; ATP-Binding Cassette Transporters; Bacterial Proteins; Binding Sites; Biological Transport; Carrier Proteins; Cysteine; Escherichia coli; Escherichia coli Proteins; Histidine; Hydrogenase; Membrane Proteins; Membrane Transport Proteins; Molecular Sequence Data; Mutagenesis, Site-Directed; Nickel | 1997 |
Genetic and clinical description of hemochromatosis probands and heterozygotes: evidence that multiple genes linked to the major histocompatibility complex are responsible for hemochromatosis.
Topics: Adult; Alleles; Aspartic Acid; Chromosomes, Human, Pair 6; Cysteine; Female; Gene Frequency; Genes, MHC Class I; Genetic Linkage; Hemochromatosis; Heterozygote; Histidine; Histocompatibility Testing; HLA Antigens; Homozygote; Humans; Iron; Male; Middle Aged; Mutation; Tyrosine; White People | 1997 |
Identification of cysteine-523 in the aspartate binding site of Escherichia coli asparagine synthetase B.
Topics: Adenosine; Adenosine Triphosphate; Aspartate-Ammonia Ligase; Aspartic Acid; Cysteine; Disulfides; Enzyme Inhibitors; Escherichia coli; Kinetics; Mutagenesis, Site-Directed | 1997 |
Effect of cysteinesulfinate on fatty acid-dependent uncoupling: modulation of recoupling by substrates of the aspartate/glutamate antiporter and diethyl pyrocarbonate.
Topics: Animals; Aspartic Acid; Atractyloside; Cysteine; Diethyl Pyrocarbonate; Fatty Acids; Glutamic Acid; Mitochondria, Liver; Neurotransmitter Agents; Rats | 1997 |
The D13C variant of Bacillus schlegelii 7Fe ferredoxin is an 8Fe ferredoxin as revealed by 1H-NMR spectroscopy.
Topics: Aspartic Acid; Bacillus; Cysteine; Ferredoxins; Genetic Variation; Ligands; Magnetic Resonance Spectroscopy; Mutagenesis, Site-Directed; Protein Engineering | 1997 |
In vivo mutational analysis of highly conserved amino acid residues of the small subunit Cpa1p of the carbamylphosphate synthetase of Saccharomyces cerevisiae.
Topics: Amino Acid Sequence; Ammonia; Ammonium Sulfate; Arginine; Aspartic Acid; Carbon-Nitrogen Ligases; Chromosome Mapping; Cysteine; Gene Expression; Glutaminase; Glutamine; Histidine; Molecular Sequence Data; Mutagenesis, Site-Directed; Plasmids; Proline; Saccharomyces cerevisiae; Sequence Analysis; Sequence Deletion; Transformation, Genetic | 1997 |
The role of the buried aspartate of Escherichia coli thioredoxin in the activation of the mixed disulfide intermediate.
Topics: Amino Acid Substitution; Aspartic Acid; Bacterial Proteins; Binding Sites; Cysteine; Disulfides; Dithiothreitol; Escherichia coli; Kinetics; Oxidation-Reduction; Protein Disulfide-Isomerases; Thioredoxins | 1997 |
Mutational analysis of the three cysteines and active-site aspartic acid 103 of ketosteroid isomerase from Pseudomonas putida biotype B.
Topics: Aspartic Acid; Binding Sites; Cysteine; Dithionitrobenzoic Acid; DNA Mutational Analysis; Enzyme Stability; Equilenin; Hydrogen Bonding; Ketosteroids; Kinetics; Models, Molecular; Pseudomonas putida; Recombinant Proteins; Spectrophotometry, Ultraviolet; Steroid Isomerases; Titrimetry | 1997 |
Cysteine and disulfide scanning reveals a regulatory alpha-helix in the cytoplasmic domain of the aspartate receptor.
Topics: Aspartic Acid; Chemotaxis; Cloning, Molecular; Cysteine; Cytoplasm; Disulfides; Escherichia coli; Methylation; Models, Molecular; Mutagenesis, Site-Directed; Protein Structure, Secondary; Receptors, Amino Acid; Salmonella typhimurium; Solvents | 1997 |
Roles of conserved arginine residues in the metal-tetracycline/H+ antiporter of Escherichia coli.
Topics: Amino Acid Sequence; Amino Acid Substitution; Antiporters; Arginine; Aspartic Acid; Bacterial Proteins; Biological Transport; Carbon Radioisotopes; Cell Membrane; Conserved Sequence; Cysteine; Escherichia coli; Ethylmaleimide; Molecular Sequence Data; Mutagenesis, Site-Directed; Protein Binding; Tetracycline; Tetracycline Resistance | 1998 |
HFE codon 63/282 (H63D/C282Y) dimorphism in German patients with genetic hemochromatosis.
Topics: Aspartic Acid; Codon; Cysteine; Female; Genotype; Germany; Hemochromatosis; Hemochromatosis Protein; Histidine; Histocompatibility Antigens Class I; HLA Antigens; Humans; Male; Membrane Proteins; Point Mutation; Polymorphism, Genetic; Tyrosine | 1998 |
Direct measurement of small ligand-induced conformational changes in the aspartate chemoreceptor using EPR.
Topics: Aspartic Acid; Bacterial Proteins; Chemoreceptor Cells; Cysteine; Electron Spin Resonance Spectroscopy; Escherichia coli Proteins; Glycine; Ligands; Membrane Proteins; Models, Molecular; Mutagenesis, Site-Directed; Protein Binding; Protein Conformation; Receptors, Cell Surface; Salmonella typhimurium; Spin Labels; Threonine | 1998 |
Structural replacement of active site monovalent cations by the epsilon-amino group of lysine in the ATPase fragment of bovine Hsc70.
Topics: Adenosine Triphosphatases; Amines; Amino Acid Substitution; Animals; Arginine; Aspartic Acid; Binding Sites; Carrier Proteins; Cations, Monovalent; Cattle; Crystallography, X-Ray; Cysteine; HSC70 Heat-Shock Proteins; HSP70 Heat-Shock Proteins; Hydrolysis; Lysine; Models, Molecular; Mutagenesis, Site-Directed; Peptide Fragments | 1998 |
Cysteine scanning of the surroundings of an alkali-ion binding site of the glutamate transporter GLT-1 reveals a conformationally sensitive residue.
Topics: Amino Acid Transport System X-AG; Amino Acids; Aspartic Acid; ATP-Binding Cassette Transporters; Binding Sites; Biological Transport; Conserved Sequence; Cysteine; Ethylmaleimide; HeLa Cells; Humans; Kainic Acid; Mesylates; Mutagenesis, Site-Directed; Potassium; Protein Conformation; Sodium; Sulfhydryl Reagents | 1998 |
Sulfhydryl oxidation of mutants with cysteine in place of acidic residues in the lactose permease.
Topics: Amino Acid Substitution; Aspartic Acid; Cysteine; Escherichia coli; Escherichia coli Proteins; Glutamic Acid; Membrane Transport Proteins; Monosaccharide Transport Proteins; Mutagenesis, Site-Directed; Oxidation-Reduction; Structure-Activity Relationship; Sulfhydryl Compounds; Sulfinic Acids; Sulfonic Acids; Symporters | 1998 |
Synthesis and characterization of a stable analog of the phosphorylated form of the chemotaxis protein CheY.
Topics: Amino Acid Substitution; Aspartic Acid; Bacterial Proteins; Chemotaxis; Cysteine; Escherichia coli; Escherichia coli Proteins; Fluorescence; Membrane Proteins; Metals; Methyl-Accepting Chemotaxis Proteins; Mutagenesis, Site-Directed; Phosphates; Phosphorylation; Protein Binding | 1998 |
Partitioning of free energy gain between the photoisomerized retinal and the protein in bacteriorhodopsin.
Topics: Amino Acid Substitution; Asparagine; Aspartic Acid; Bacterial Proteins; Bacteriorhodopsins; Cysteine; Energy Transfer; Halobacterium salinarum; Hydrogen-Ion Concentration; Isomerism; Mutagenesis, Site-Directed; Phenylalanine; Photochemistry; Retinaldehyde; Spectrophotometry; Spectroscopy, Fourier Transform Infrared; Spectrum Analysis, Raman | 1998 |
Calculations of electrostatic interactions and pKas in the active site of Escherichia coli thioredoxin.
Topics: Aspartic Acid; Binding Sites; Crystallography, X-Ray; Cysteine; Escherichia coli; Hydrogen-Ion Concentration; Lysine; Mathematical Computing; Models, Chemical; Oxidation-Reduction; Protein Conformation; Static Electricity; Thermodynamics; Thioredoxins | 1998 |
Structure of the interhelical loops and carboxyl terminus of bacteriorhodopsin by X-ray diffraction using site-directed heavy-atom labeling.
Topics: Alanine; Amino Acid Sequence; Aspartic Acid; Bacteriorhodopsins; Chloromercuribenzoates; Cysteine; Glycine; Isotope Labeling; Molecular Sequence Data; Mutagenesis, Site-Directed; Photochemistry; Protein Structure, Secondary; Proton Pumps; Spectrophotometry, Ultraviolet; Valine; X-Ray Diffraction | 1998 |
Cysteine and disulfide scanning reveals two amphiphilic helices in the linker region of the aspartate chemoreceptor.
Topics: Aspartic Acid; Chemotaxis; Cysteine; Disulfides; Escherichia coli; Models, Molecular; Protein Engineering; Protein Structure, Secondary; Receptors, Amino Acid; Salmonella typhimurium; Signal Transduction; Solvents; Sulfhydryl Compounds | 1998 |
Mutations in HFE, the hemochromatosis candidate gene, in patients with NIDDM.
Topics: Amino Acid Substitution; Aspartic Acid; Cysteine; Diabetes Mellitus, Type 2; Hemochromatosis; Hemochromatosis Protein; Histidine; Histocompatibility Antigens Class I; HLA Antigens; Homozygote; Humans; Major Histocompatibility Complex; Membrane Proteins; Point Mutation; Reference Values; Tyrosine | 1998 |
Frequency of the HFE C282Y and H63D mutations in distinct ethnic groups living in Spain.
Topics: Alleles; Aspartic Acid; Cysteine; Ethnicity; Genotype; Hemochromatosis; Hemochromatosis Protein; Histidine; Histocompatibility Antigens Class I; HLA Antigens; Humans; Membrane Proteins; Mutation; Roma; Spain; Tyrosine | 1998 |
Delta T 14/Delta D 15 Azotobacter vinelandii ferredoxin I: creation of a new CysXXCysXXCys motif that ligates a [4Fe-4S] cluster.
Topics: Amino Acid Sequence; Aspartic Acid; Azotobacter vinelandii; Circular Dichroism; Cysteine; Electrochemistry; Electron Spin Resonance Spectroscopy; Electron Transport; Ferredoxins; Iron; Molecular Sequence Data; Mutagenesis, Site-Directed; Threonine | 1998 |
Detection of a conserved alpha-helix in the kinase-docking region of the aspartate receptor by cysteine and disulfide scanning.
Topics: Aspartic Acid; Bacterial Proteins; Chemotaxis; Cysteine; Cytoplasm; Disulfides; Enzyme Activation; Escherichia coli Proteins; Histidine Kinase; Membrane Proteins; Methyl-Accepting Chemotaxis Proteins; Protein Kinases; Protein Structure, Secondary; Receptors, Amino Acid; Recombinant Proteins; Signal Transduction; Substrate Specificity | 1998 |
A conserved aspartate residue, Asp187, is important for Na+-dependent proline binding and transport by the Na+/proline transporter of Escherichia coli.
Topics: Amino Acid Sequence; Amino Acid Substitution; Amino Acid Transport Systems, Neutral; Aspartic Acid; Biological Transport, Active; Blotting, Western; Conserved Sequence; Cysteine; Iodoacetamide; Iodoacetic Acid; Kinetics; Ligands; Membrane Transport Proteins; Molecular Sequence Data; Proline; Protein Binding; Sequence Homology, Amino Acid; Sodium | 1998 |
Investigation of a catalytic zinc binding site in Escherichia coli L-threonine dehydrogenase by site-directed mutagenesis of cysteine-38.
Topics: Alcohol Oxidoreductases; Aspartic Acid; Binding Sites; Catalysis; Cations, Divalent; Circular Dichroism; Cysteine; Enzyme Activation; Escherichia coli; Hydrogen-Ion Concentration; Molecular Weight; Mutagenesis, Site-Directed; Protein Conformation; Serine; Spectrophotometry, Atomic; Zinc | 1998 |
Divercin V41, a new bacteriocin with two disulphide bonds produced by Carnobacterium divergens V41: primary structure and genomic organization.
Topics: Amino Acid Sequence; Aspartic Acid; Bacterial Proteins; Bacteriocins; Cloning, Molecular; Cysteine; Disulfides; Endopeptidases; Genomic Library; Lactobacillaceae; Mass Spectrometry; Metalloendopeptidases; Molecular Sequence Data; Molecular Weight; Open Reading Frames; Peptides; Polymerase Chain Reaction; Pyridines; Sequence Alignment; Sequence Analysis | 1998 |
Autocatalytic activation of human legumain at aspartic acid residues.
Topics: Amino Acid Sequence; Animals; Aspartic Acid; Blotting, Western; Catalytic Domain; Cell Line; Cysteine; Cysteine Endopeptidases; Enzyme Activation; Expressed Sequence Tags; Histidine; Humans; Hydrogen-Ion Concentration; Kinetics; Mice; Molecular Sequence Data; Mutagenesis, Site-Directed; Plant Proteins; Recombinant Fusion Proteins; Sequence Alignment; Substrate Specificity | 1998 |
Alternative splicing results in differential expression, activity, and localization of the two forms of arginyl-tRNA-protein transferase, a component of the N-end rule pathway.
Topics: Alternative Splicing; Amino Acid Sequence; Aminoacyltransferases; Animals; Arabidopsis; Aspartic Acid; Base Sequence; beta-Galactosidase; Cell Line, Transformed; Cell Nucleus; Cysteine; Cytosol; DNA, Complementary; Drosophila melanogaster; Exons; Gene Expression Regulation; Glutamic Acid; Humans; Mice; Molecular Sequence Data | 1999 |
Three-dimensional structure of phosphoenolpyruvate carboxylase: a proposed mechanism for allosteric inhibition.
Topics: Allosteric Regulation; Amino Acid Sequence; Amino Acid Substitution; Arginine; Aspartic Acid; Computer Simulation; Conserved Sequence; Crystallography, X-Ray; Cysteine; Dimerization; Escherichia coli; Models, Molecular; Molecular Sequence Data; Phosphoenolpyruvate Carboxylase; Protein Structure, Secondary; Sequence Alignment; Sequence Homology, Amino Acid; Zea mays | 1999 |
D-Aspartate stimulation of testosterone synthesis in rat Leydig cells.
Topics: Animals; Aspartic Acid; Bucladesine; Cholesterol; Chorionic Gonadotropin; Cysteine; Leydig Cells; Male; Neurotransmitter Agents; Rats; Rats, Sprague-Dawley; Testis; Testosterone | 1999 |
Analysis of zinc binding sites in protein crystal structures.
Topics: Aspartic Acid; Binding Sites; Catalysis; Chlorine; Crystallography, X-Ray; Cysteine; Databases, Factual; Glutamine; Histidine; Models, Molecular; Molecular Conformation; Nitrogen; Oxygen; Protein Binding; Sulfur; Zinc | 1998 |
The cysteine-proximal aspartates in the Fx-binding niche of photosystem I. Effect of alanine and lysine replacements on photoautotrophic growth, electron transfer rates, single-turnover flash efficiency, and EPR spectral properties.
Topics: Alanine; Amino Acid Substitution; Aspartic Acid; Bacterial Proteins; Binding Sites; Cyanobacteria; Cysteine; Electron Spin Resonance Spectroscopy; Electron Transport; Kinetics; Lysine; Membrane Proteins; Mutagenesis, Site-Directed; NADP; Photosynthetic Reaction Center Complex Proteins; Photosystem I Protein Complex; Structure-Activity Relationship | 1999 |
Protein side-chain conformation: a systematic variation of chi 1 mean values with resolution - a consequence of multiple rotameric states?
Topics: Asparagine; Aspartic Acid; Crystallography, X-Ray; Cysteine; Protein Conformation; Proteins; Rotation; Solubility; Solvents | 1999 |
Binding of calcium ions to bacteriorhodopsin.
Topics: Aspartic Acid; Bacteriorhodopsins; Binding Sites; Biophysical Phenomena; Biophysics; Calcium; Calorimetry; Cysteine; Halobacterium salinarum; Hydrogen-Ion Concentration; Mutation; Protein Binding; Protons; Surface Properties | 1999 |
Electrostatic and aromatic microdomains within the binding-site crevice of the D2 receptor: contributions of the second membrane-spanning segment.
Topics: Amino Acid Substitution; Aspartic Acid; Binding, Competitive; Cell Line; Cell Membrane; Cysteine; Dopamine Antagonists; Ethyl Methanesulfonate; Humans; Mesylates; Models, Molecular; Mutagenesis, Site-Directed; Peptide Fragments; Protein Binding; Protein Structure, Tertiary; Receptors, Dopamine D2; Static Electricity; Sulpiride | 1999 |
Signaling domain of the aspartate receptor is a helical hairpin with a localized kinase docking surface: cysteine and disulfide scanning studies.
Topics: Amino Acid Substitution; Aspartic Acid; Bacterial Proteins; Chemotaxis; Cysteine; Disulfides; Escherichia coli; Escherichia coli Proteins; Histidine Kinase; Membrane Proteins; Methyl-Accepting Chemotaxis Proteins; Models, Molecular; Mutagenesis, Site-Directed; Peptide Fragments; Protein Engineering; Protein Kinases; Protein Structure, Secondary; Receptors, Amino Acid; Signal Transduction; Solvents; Surface Properties | 1999 |
The aspartate receptor cytoplasmic domain: in situ chemical analysis of structure, mechanism and dynamics.
Topics: Aspartic Acid; Cysteine; Disulfides; Models, Molecular; Protein Conformation; Receptors, Amino Acid; Receptors, Cytoplasmic and Nuclear | 1999 |
Construction and characterization of mutants of the TEM-1 beta-lactamase containing amino acid substitutions associated with both extended-spectrum resistance and resistance to beta-lactamase inhibitors.
Topics: Amino Acid Substitution; Arginine; Asparagine; Aspartic Acid; beta-Lactamase Inhibitors; beta-Lactamases; Cephalosporin Resistance; Cysteine; Enzyme Inhibitors; Leucine; Methionine; Microbial Sensitivity Tests; Mutagenesis, Site-Directed; Penicillin Resistance; Phenotype | 1999 |
Effect of serinate ligation at each of the iron sites of the [Fe4S4] cluster of Pyrococcus furiosus ferredoxin on the redox, spectroscopic, and biological properties.
Topics: Amino Acid Sequence; Aspartic Acid; Circular Dichroism; Cysteine; Electrochemistry; Electron Spin Resonance Spectroscopy; Ferredoxin-NADP Reductase; Ferredoxins; Iron; Ligands; Molecular Sequence Data; Mutagenesis, Site-Directed; Oxidation-Reduction; Pyrococcus furiosus; Serine; Spectrophotometry, Ultraviolet; Spectrum Analysis, Raman; Sulfur | 1999 |
Engineering cytochrome c peroxidase into cytochrome P450: a proximal effect on heme-thiolate ligation.
Topics: Aspartic Acid; Circular Dichroism; Cysteine; Cytochrome c Group; Cytochrome P-450 Enzyme System; Cytochrome-c Peroxidase; Cytochromes c; Electron Spin Resonance Spectroscopy; Escherichia coli; Ferric Compounds; Heme; Histidine; Imidazoles; Leucine; Ligands; Mutagenesis, Site-Directed; Protein Engineering; Spectrophotometry, Ultraviolet | 1999 |
Molecular defects in variant forms of mannose-binding protein associated with immunodeficiency.
Topics: Amino Acid Sequence; Amino Acid Substitution; Animals; Arginine; Aspartic Acid; Carrier Proteins; Collectins; Complement Fixation Tests; Cysteine; Disulfides; Glutamic Acid; Glycine; Humans; Immunologic Deficiency Syndromes; Mannans; Molecular Sequence Data; Point Mutation; Protein Processing, Post-Translational; Rats | 1999 |
Mutations in the rod outer segment membrane guanylate cyclase in a cone-rod dystrophy cause defects in calcium signaling.
Topics: Animals; Arginine; Aspartic Acid; Calcium Signaling; Calcium-Binding Proteins; Cattle; Cysteine; Enzyme Activation; Glutamic Acid; Guanylate Cyclase; Guanylate Cyclase-Activating Proteins; Humans; Mutagenesis, Insertional; Protein Binding; Receptors, Cell Surface; Retinal Degeneration; Rod Cell Outer Segment; S100 Proteins | 1999 |
Time-resolved site-directed spin-labeling studies of bacteriorhodopsin: loop-specific conformational changes in M.
Topics: Alanine; Amino Acid Sequence; Amino Acid Substitution; Aspartic Acid; Bacteriorhodopsins; Cysteine; Electron Spin Resonance Spectroscopy; Electrophoresis, Polyacrylamide Gel; Kinetics; Mesylates; Molecular Sequence Data; Mutagenesis, Site-Directed; Photolysis; Protein Conformation; Protein Structure, Secondary; Purple Membrane; Spectrophotometry, Ultraviolet; Spin Labels | 2000 |
Study of the alkylation propensity of cations generated by acidolytic cleavage of protecting groups in Boc chemistry.
Topics: Alkylation; Aspartic Acid; Biochemistry; Cations; Chromatography, High Pressure Liquid; Cysteine; Peptides | 2000 |
Clinical characteristics of type 2 diabetes in patients with mutations of HFE.
Topics: Amino Acid Substitution; Aspartic Acid; Cysteine; Diabetes Mellitus, Type 2; Female; Ferritins; Hemochromatosis Protein; Heterozygote; Histidine; Histocompatibility Antigens Class I; HLA Antigens; Humans; Insulin Resistance; Iron; Major Histocompatibility Complex; Male; Membrane Proteins; Middle Aged; Point Mutation; Transferrin; Tyrosine | 2000 |
Investigation of spectroscopic intermediates during copper-binding and TPQ formation in wild-type and active-site mutants of a copper-containing amine oxidase from yeast.
Topics: Amine Oxidase (Copper-Containing); Asparagine; Aspartic Acid; Binding Sites; Coenzymes; Copper; Cysteine; Dihydroxyphenylalanine; Glutamic Acid; Glutamine; Histidine; Mutagenesis, Site-Directed; Oxygen Consumption; Pichia; Recombinant Proteins; Spectrophotometry, Atomic; Spectrophotometry, Ultraviolet | 2000 |
Substrate-stereoselectivity of a high-affinity glutamate transporter cloned from the CNS of the cockroach Diploptera punctata.
Topics: Amino Acid Sequence; Amino Acid Transport System X-AG; Animals; Aspartic Acid; ATP-Binding Cassette Transporters; Baculoviridae; Biological Transport; Cockroaches; Cysteine; Gene Library; Glutamates; Kinetics; Molecular Sequence Data; Recombinant Proteins; Sequence Homology, Amino Acid; Species Specificity; Stereoisomerism; Zinc | 2000 |
Functional conservation in the putative substrate binding site of the sucrose permease from Escherichia coli.
Topics: Alkylation; Arginine; Aspartic Acid; Binding Sites; Biological Transport, Active; Chromatography, Affinity; Conserved Sequence; Cysteine; Escherichia coli; Escherichia coli Proteins; Ethylmaleimide; Iodoacetic Acid; Membrane Transport Proteins; Mutagenesis, Site-Directed; Serine; Substrate Specificity; Sucrose | 2000 |
Possible interference between tissue-non-specific alkaline phosphatase with an Arg54-->Cys substitution and acounterpart with an Asp277-->Ala substitution found in a compound heterozygote associated with severe hypophosphatasia.
Topics: Alanine; Alkaline Phosphatase; Amino Acid Substitution; Animals; Arginine; Aspartic Acid; COS Cells; Cysteine; DNA, Complementary; Heterozygote; Hypophosphatasia; Mutation, Missense; Transfection | 2000 |
Genotype-phenotype relationships in U.S. melanoma-prone families with CDKN2A and CDK4 mutations.
Topics: Adolescent; Adult; Age Factors; Aged; Arginine; Aspartic Acid; Cyclin-Dependent Kinases; Cysteine; Genes, p16; Genotype; Germ-Line Mutation; Glycine; Haplotypes; Humans; Melanoma; Middle Aged; Nevus; Pancreatic Neoplasms; Phenotype; Skin Neoplasms; Statistics, Nonparametric; Tryptophan; United States; Valine | 2000 |
Structure of arylamine N-acetyltransferase reveals a catalytic triad.
Topics: Acetanilides; Amino Acid Sequence; Arylamine N-Acetyltransferase; Aspartic Acid; Binding Sites; Catalysis; Crystallography, X-Ray; Cysteine; Histidine; Models, Molecular; Molecular Sequence Data; Protein Folding; Protein Structure, Secondary; Protein Structure, Tertiary; Salmonella typhimurium; Sequence Alignment; Structure-Activity Relationship | 2000 |
Kiwi protein inhibitor of pectin methylesterase amino-acid sequence and structural importance of two disulfide bridges.
Topics: Amino Acid Sequence; Aspartic Acid; Carboxylic Ester Hydrolases; Chromatography, High Pressure Liquid; Circular Dichroism; Cysteine; Disulfides; DNA, Complementary; Fruit; Molecular Sequence Data; Plant Proteins; Protein Structure, Secondary; Sequence Analysis, Protein; Sequence Homology, Amino Acid | 2000 |
Impaired secretion of rat mannose-binding protein resulting from mutations in the collagen-like domain.
Topics: Amino Acid Substitution; Animals; Arginine; Aspartic Acid; Carrier Proteins; CHO Cells; Collagen; Collectins; Complement Fixation Tests; Cricetinae; Cysteine; Endoplasmic Reticulum; Glutamic Acid; Glycine; Humans; Lectins; Lysine; Mannans; Mutagenesis, Site-Directed; Protein Processing, Post-Translational; Protein Structure, Tertiary; Proteins; Rats; Time Factors; Transfection | 2000 |
A structure-function study of a proton transport pathway in the gamma-class carbonic anhydrase from Methanosarcina thermophila.
Topics: Alanine; Amino Acid Substitution; Aspartic Acid; Biological Transport; Carbonic Anhydrases; Cysteine; Deuterium; Escherichia coli; Genetic Variation; Glutamic Acid; Glutamine; Histidine; Hydrogen-Ion Concentration; Kinetics; Lysine; Methanosarcina; Mutagenesis, Site-Directed; Protons; Serine; Solvents; Structure-Activity Relationship; Threonine; Tryptophan | 2000 |
Functional analysis of the active site of a metallo-beta-lactamase proliferating in Japan.
Topics: Anti-Bacterial Agents; Apoenzymes; Aspartic Acid; beta-Lactam Resistance; beta-Lactamases; beta-Lactams; Binding Sites; Binding, Competitive; Cysteine; Dose-Response Relationship, Drug; Escherichia coli; Histidine; Humans; Japan; Kinetics; Klebsiella pneumoniae; Ligands; Microbial Sensitivity Tests; Mutagenesis, Site-Directed; Zinc | 2000 |
Mechanism of phosphoanhydride cleavage by baculovirus phosphatase.
Topics: Adenosine Diphosphate; Adenosine Triphosphatases; Alanine; Amino Acid Sequence; Animals; Aspartic Acid; Baculoviridae; Catalysis; Cloning, Molecular; Cysteine; DNA Mutational Analysis; Dose-Response Relationship, Drug; Escherichia coli; Humans; Hydrogen-Ion Concentration; Kinetics; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation, Missense; Organophosphates; Oxygen; Phosphoric Monoester Hydrolases; Phosphorus; Plasmids; Recombinant Proteins; RNA, Messenger; Sequence Homology, Amino Acid; Serine; Structure-Activity Relationship; Temperature; Time Factors; Transformation, Genetic | 2000 |
The Na+/Ca2+ exchanger NCX1 has oppositely oriented reentrant loop domains that contain conserved aspartic acids whose mutation alters its apparent Ca2+ affinity.
Topics: Amino Acid Sequence; Amino Acid Substitution; Animals; Asparagine; Aspartic Acid; Binding Sites; Calcium; Cattle; Cell Membrane; Conserved Sequence; Cricetinae; Cysteine; Dogs; Membrane Potentials; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Protein Structure, Secondary; Rats; Recombinant Proteins; Repetitive Sequences, Amino Acid; Sequence Alignment; Sequence Homology, Amino Acid; Sodium; Sodium-Calcium Exchanger; Transfection | 2000 |
Mutational analysis of metallo-beta-lactamase CcrA from Bacteroides fragilis.
Topics: Amino Acid Substitution; Asparagine; Aspartic Acid; Bacterial Proteins; Bacteroides fragilis; beta-Lactamases; Cysteine; Deuterium; DNA Mutational Analysis; DNA, Bacterial; Gene Expression Regulation, Bacterial; Hydrogen-Ion Concentration; Kinetics; Metalloproteins; Mutagenesis, Site-Directed; Protons; Recombinant Proteins; Serine; Solvents; Zinc | 2000 |
NMR structures of thioredoxin m from the green alga Chlamydomonas reinhardtii.
Topics: Amino Acid Sequence; Animals; Aspartic Acid; Binding Sites; Chlamydomonas reinhardtii; Chloroplast Thioredoxins; Cysteine; Models, Chemical; Models, Molecular; Molecular Sequence Data; Motion; Nuclear Magnetic Resonance, Biomolecular; Oxidation-Reduction; Protein Structure, Tertiary; Sequence Homology, Amino Acid; Thioredoxins | 2000 |
Characterization of electrically evoked [3H]-D-aspartate release from hippocampal slices.
Topics: Animals; Aspartic Acid; Calcium; Cysteine; Diffusion Chambers, Culture; Dose-Response Relationship, Drug; Electric Stimulation; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Glutamic Acid; Hippocampus; In Vitro Techniques; Magnesium; Neurotransmitter Agents; Purinergic P1 Receptor Agonists; Rats; Rats, Sprague-Dawley; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate; Stereoisomerism; Tritium | 2001 |
Haemochromatosis: automated detection of the two point mutations in the HFE gene: Cys282Tyr and His63Asp.
Topics: Aspartic Acid; Cysteine; DNA Mutational Analysis; Hemochromatosis; Hemochromatosis Protein; Heterozygote; Histidine; Histocompatibility Antigens Class I; HLA Antigens; Humans; Membrane Proteins; Mutation; Point Mutation; Polymerase Chain Reaction; Reproducibility of Results; Sensitivity and Specificity; Tyrosine | 2000 |
Molecular motion of spin labeled side chains in alpha-helices: analysis by variation of side chain structure.
Topics: Amino Acid Substitution; Anisotropy; Arginine; Aspartic Acid; Bacteriophage T4; Cysteine; Electron Spin Resonance Spectroscopy; Free Radicals; Models, Molecular; Muramidase; Mutagenesis, Site-Directed; Nitrogen Oxides; Protein Conformation; Protein Structure, Secondary; Spin Labels; Spin Trapping; Temperature; Valine | 2001 |
A fluorescent sensor of the phosphorylation state of nucleoside diphosphate kinase and its use to monitor nucleoside diphosphate concentrations in real time.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Aspartic Acid; Binding Sites; Coumarins; Cysteine; Fluorescent Dyes; Guanosine Diphosphate; Humans; Kinetics; Mass Spectrometry; Mutagenesis, Site-Directed; Myosin Subfragments; Myxococcus xanthus; Nucleoside-Diphosphate Kinase; Phosphorylation; Purine Nucleotides; Rabbits; rho GTP-Binding Proteins; Solutions; Spectrometry, Fluorescence | 2001 |
Eubacterial arylamine N-acetyltransferases - identification and comparison of 18 members of the protein family with conserved active site cysteine, histidine and aspartate residues.
Topics: Amino Acid Motifs; Amino Acid Sequence; Arylamine N-Acetyltransferase; Aspartic Acid; Bacterial Proteins; Blotting, Western; Catalytic Domain; Conserved Sequence; Cysteine; Enterobacteriaceae; Gram-Positive Bacteria; Histidine; Models, Molecular; Molecular Sequence Data; Operon; Polymerase Chain Reaction; Polymorphism, Genetic; Proteobacteria; Sequence Alignment; Substrate Specificity | 2001 |
Asparagine 23 and aspartate 305 are essential residues in the active site of UDP-N-acetylglucosamine enolpyruvyl transferase from Enterobacter cloacae.
Topics: Alkyl and Aryl Transferases; Amino Acid Substitution; Asparagine; Aspartic Acid; Binding Sites; Catalysis; Cysteine; Enterobacter cloacae; Enzyme Inhibitors; Fosfomycin; Mutagenesis, Site-Directed; Phosphates; Phosphoenolpyruvate; Recombinant Proteins; Uridine Diphosphate N-Acetylglucosamine | 2001 |
Crystal structure of 3,4-dihydroxy-2-butanone 4-phosphate synthase of riboflavin biosynthesis.
Topics: Aspartic Acid; Binding Sites; Catalysis; Crystallography, X-Ray; Cysteine; Dimerization; Escherichia coli; Glutamic Acid; Histidine; Intramolecular Transferases; Magnesium; Models, Chemical; Models, Molecular; Protein Structure, Secondary; Riboflavin; Riboflavin Synthase | 2001 |
Biochemical characterization and identification of catalytic residues in alpha-glucuronidase from Bacillus stearothermophilus T-6.
Topics: Alanine; Amino Acid Sequence; Aspartic Acid; Binding Sites; Calorimetry, Differential Scanning; Catalysis; Catalytic Domain; Chromatography, Gel; Cysteine; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Escherichia coli; Geobacillus stearothermophilus; Glutamic Acid; Glycoside Hydrolases; Hot Temperature; Hydrogen-Ion Concentration; Kinetics; Molecular Sequence Data; Mutagenesis, Site-Directed; Protein Binding; Sequence Analysis, Protein; Sequence Homology, Amino Acid; Temperature; Trioses | 2001 |
Probing Tat peptide-TAR RNA interactions by psoralen photo-cross-linking.
Topics: Amino Acid Sequence; Aspartic Acid; Cross-Linking Reagents; Cysteine; Ficusin; Gene Products, tat; HIV Long Terminal Repeat; HIV-1; Humans; Molecular Sequence Data; Peptide Fragments; Photochemistry; Pyrones; RNA, Viral; tat Gene Products, Human Immunodeficiency Virus; Threonine; Uridine | 2001 |
Association studies between haemochromatosis gene mutations and the risk of cardiovascular diseases.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Arteriosclerosis; Aspartic Acid; Brain Infarction; Cardiovascular Diseases; Case-Control Studies; Cysteine; Female; France; Genetic Predisposition to Disease; Genotype; Hemochromatosis; Hemochromatosis Protein; Histidine; Histocompatibility Antigens Class I; HLA Antigens; Humans; Male; Membrane Proteins; Middle Aged; Mutation; Myocardial Infarction; Northern Ireland; Polymorphism, Genetic; Prevalence; Prospective Studies; Tyrosine; Ultrasonography; United Kingdom | 2001 |
Novel intra- and inter-molecular sulfinamide bonds in S100A8 produced by hypochlorite oxidation.
Topics: Amino Acid Sequence; Antigens, Differentiation; Aspartic Acid; Binding Sites; Calcium-Binding Proteins; Calgranulin A; Chromatography, High Pressure Liquid; Cyclohexanones; Cysteine; Dimerization; Disulfides; Dithiothreitol; Dose-Response Relationship, Drug; Hydrogen Peroxide; Hypochlorous Acid; Lysine; Models, Chemical; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; Neutrophils; Oxygen; Peptides; Peroxidase; Spectrometry, Mass, Electrospray Ionization; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Sulfenic Acids; Sulfur; Tetradecanoylphorbol Acetate; Time Factors | 2001 |
Endogenous sulphur-containing amino acids: potent agonists at presynaptic metabotropic glutamate autoreceptors in the rat central nervous system.
Topics: Amino Acids, Sulfur; Animals; Aspartic Acid; Autoreceptors; Calcium; Central Nervous System; Cysteic Acid; Cysteine; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; gamma-Aminobutyric Acid; Glycine; Male; Neurotransmitter Agents; Presynaptic Terminals; Prosencephalon; Pyridines; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate; Resorcinols; Tetrodotoxin; Tritium | 2001 |
NAD+-dependent DNA ligase encoded by a eukaryotic virus.
Topics: Alanine; Amino Acid Motifs; Amino Acid Sequence; Aspartic Acid; Base Sequence; Catalysis; Cysteine; DNA Ligases; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Evolution, Molecular; Gene Deletion; Genetic Vectors; Models, Biological; Molecular Sequence Data; Mutation; NAD; Phylogeny; Poxviridae; Protein Binding; Protein Structure, Tertiary; Sequence Homology, Amino Acid; Substrate Specificity; Time Factors; Tyrosine; Zinc; Zinc Fingers | 2001 |
beta-Ketoacyl-[acyl carrier protein] synthase I of Escherichia coli: aspects of the condensation mechanism revealed by analyses of mutations in the active site pocket.
Topics: 3-Oxoacyl-(Acyl-Carrier-Protein) Synthase; Aspartic Acid; Binding Sites; Carboxy-Lyases; Catalysis; Chromatography; Cysteine; DNA; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Escherichia coli; Glutamic Acid; Glutamine; Histidine; Hydrogen-Ion Concentration; Isoenzymes; Lysine; Models, Molecular; Mutagenesis, Site-Directed; Mutation; Myristic Acid; Plasmids; Protein Binding; Recombinant Proteins | 2001 |
Hemochromatosis gene variants in patients with cardiomyopathy.
Topics: Adolescent; Adult; Aged; Aspartic Acid; Cardiomyopathies; Cysteine; Disease Progression; Female; Genotype; Heart Failure; Hemochromatosis; Histidine; Humans; Logistic Models; Male; Middle Aged; Mutation, Missense; Prognosis; Tyrosine | 2001 |
Disordered to ordered folding in the regulation of diphtheria toxin repressor activity.
Topics: Amino Acid Substitution; Anilino Naphthalenesulfonates; Aspartic Acid; Bacterial Proteins; Binding Sites; Crystallography, X-Ray; Cysteine; DNA-Binding Proteins; Escherichia coli; Models, Molecular; Mutagenesis, Site-Directed; Nuclear Magnetic Resonance, Biomolecular; Peptide Fragments; Protein Conformation; Protein Folding; Recombinant Proteins; Thrombin | 2001 |
Methylmercury inhibits cysteine uptake in cultured primary astrocytes, but not in neurons.
Topics: Animals; Animals, Newborn; Aspartic Acid; Astrocytes; Carrier Proteins; Cells, Cultured; Central Nervous System; Cysteine; Dose-Response Relationship, Drug; Excitatory Amino Acid Transporter 1; Fetus; Glutathione; Mercury Poisoning, Nervous System; Methylmercury Compounds; Neurons; Neurotoxins; Rats; Rats, Sprague-Dawley; Serine; Sodium | 2001 |
C282Y and H63D mutations in the HFE gene have no effect on iron overload disorders in Japan.
Topics: Adult; Asian People; Aspartic Acid; Cysteine; Female; Hemochromatosis; Hemochromatosis Protein; Hepatitis C, Chronic; Histidine; Histocompatibility Antigens Class I; HLA Antigens; Humans; Iron Overload; Japan; Liver Diseases; Male; Membrane Proteins; Middle Aged; Point Mutation; Polymerase Chain Reaction; Tyrosine | 2001 |
Lipoprotein sorting signals evaluated as the LolA-dependent release of lipoproteins from the cytoplasmic membrane of Escherichia coli.
Topics: Aspartic Acid; Cell Division; Cell Membrane; Cysteine; Cytoplasm; DNA Primers; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Escherichia coli; Escherichia coli Proteins; Lipoproteins; Periplasmic Binding Proteins; Plasmids; Precipitin Tests; Protein Binding; Protein Structure, Tertiary; Protein Transport; Serine | 2001 |
Synthesis and biochemical characterization of a phosphorylated analogue of the response regulator CheB.
Topics: Aspartic Acid; Bacterial Proteins; Catalytic Domain; Chromatography, High Pressure Liquid; Cysteine; Escherichia coli; Esterases; Glutamic Acid; Glutamine; Magnesium; Mass Spectrometry; Methylation; Models, Chemical; Mutagenesis, Site-Directed; Mutation; Phosphates; Phosphorylation; Protein Binding; Protein Structure, Tertiary; Signal Transduction; Time Factors | 2001 |
Targeted disulfide cross-linking of the MotB protein of Escherichia coli: evidence for two H(+) channels in the stator Complex.
Topics: Aspartic Acid; Bacterial Proteins; Cell Membrane; Cross-Linking Reagents; Cysteine; Dimerization; Disulfides; Electrophoresis, Polyacrylamide Gel; Escherichia coli; Ethylmaleimide; Hydrogen; Immunoblotting; Iodine; Ions; Mesylates; Models, Biological; Mutation; Oxygen; Plasmids; Protein Binding; Protein Conformation; Protein Structure, Secondary; Protein Structure, Tertiary; Protons | 2001 |
The frequency of C282Y and H63D mutations in Hemochromatosis gene in native Estonians.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Alleles; Aspartic Acid; Cysteine; DNA Mutational Analysis; DNA Primers; Estonia; Female; Gene Frequency; Genotype; Hemochromatosis; Histidine; Humans; Male; Middle Aged; Mutation; Polymerase Chain Reaction; Tyrosine | 2001 |
Glycosylasparaginase inhibition studies: competitive inhibitors, transition state mimics, noncompetitive inhibitors.
Topics: Acetylglucosamine; Aspartic Acid; Aspartylglucosylaminase; Cysteine; Enzyme Inhibitors; Humans; Molecular Structure; Propionates; Serine Endopeptidases | 2001 |
Crystal structure of quinohemoprotein amine dehydrogenase from Pseudomonas putida. Identification of a novel quinone cofactor encaged by multiple thioether cross-bridges.
Topics: Amino Acids; Aspartic Acid; Binding Sites; Catalytic Domain; Crystallography, X-Ray; Cysteine; Dipeptides; Glutamic Acid; Indolequinones; Models, Molecular; Oxidoreductases Acting on CH-NH Group Donors; Protein Conformation; Protein Folding; Protein Structure, Tertiary; Pseudomonas putida; Quinones; Sulfides | 2002 |
Cadmium resistance conferred to yeast by a non-metallothionein-encoding gene of the earthworm Enchytraeus.
Topics: Amino Acid Sequence; Animals; Aspartic Acid; Blotting, Western; Cadmium; Cysteine; DNA, Complementary; Dose-Response Relationship, Drug; Drug Resistance; Metallothionein; Mice; Microscopy, Confocal; Models, Genetic; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; Oligochaeta; Phenotype; Proline; Protein Binding; Protein Structure, Tertiary; Proteins; Sequence Homology, Amino Acid | 2002 |
Evidence for an initiation site for hen lysozyme folding from the reduced form using its dissected peptide fragments.
Topics: Animals; Aspartic Acid; Binding Sites; Chickens; Chromatography, Ion Exchange; Circular Dichroism; Cysteine; Disulfides; Dose-Response Relationship, Drug; Glycine; Hydrogen-Ion Concentration; Kinetics; Lysine; Models, Molecular; Muramidase; Mutation; Oxygen; Peptides; Protein Folding; Protein Structure, Tertiary | 2001 |
Arginine-349 and aspartate-373 of the Na(+)/dicarboxylate cotransporter are conformationally sensitive residues.
Topics: Amino Acid Substitution; Animals; Arginine; Aspartic Acid; Binding Sites; Biotinylation; Cell Membrane; Cysteine; Dicarboxylic Acid Transporters; Female; Kinetics; Models, Molecular; Mutagenesis, Site-Directed; Oocytes; Organic Anion Transporters, Sodium-Dependent; Protein Conformation; Protein Structure, Secondary; Recombinant Proteins; Sodium; Substrate Specificity; Symporters | 2002 |
Importance of Na,K-ATPase residue alpha 1-Arg544 in the segment Arg544-Asp567 for high-affinity binding of ATP, ADP, or MgATP.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Alanine; Amino Acid Substitution; Animals; Arginine; Asparagine; Aspartic Acid; Binding Sites; Conserved Sequence; Cysteine; Glutamic Acid; Magnesium; Mutagenesis, Site-Directed; Peptide Fragments; Phosphorylation; Saccharomyces cerevisiae; Serine; Sodium-Potassium-Exchanging ATPase; Swine; Thermodynamics | 2002 |
Mapping of a ligand-binding site for the human thromboxane A2 receptor protein.
Topics: Amino Acid Sequence; Aspartic Acid; Binding Sites; Binding, Competitive; Blood Platelets; Cysteine; Dose-Response Relationship, Immunologic; Enzyme-Linked Immunosorbent Assay; Flow Cytometry; Glycine; Humans; Ligands; Models, Chemical; Molecular Sequence Data; Platelet Aggregation; Precipitin Tests; Protein Binding; Protein Structure, Tertiary; Receptors, Thromboxane; Signal Transduction; Spectrometry, Fluorescence; Trypsin | 2002 |
Insights into the structure and dynamics of the dinuclear zinc beta-lactamase site from Bacteroides fragilis.
Topics: Aspartic Acid; Bacteroides fragilis; beta-Lactamases; Binding Sites; Computer Simulation; Cysteine; Hydrophobic and Hydrophilic Interactions; Metalloproteins; Models, Molecular; Molecular Conformation; Protein Conformation; Sodium; Zinc; Zinc Compounds | 2002 |
Catalytic function and local proton structure at the type 2 copper of nitrite reductase: the correlation of enzymatic pH dependence, conserved residues, and proton hyperfine structure.
Topics: Amino Acid Substitution; Aspartic Acid; Binding Sites; Catalysis; Conserved Sequence; Copper; Cysteine; Cytochrome c Group; Cytochromes c; Electron Spin Resonance Spectroscopy; Hydrogen-Ion Concentration; Kinetics; Mutagenesis, Site-Directed; Nitrite Reductases; Protons; Rhodobacter sphaeroides; Saccharomyces cerevisiae Proteins | 2002 |
Prevalence of hemochromatosis-related symptoms among individuals with mutations in the HFE gene.
Topics: Adult; Aged; Aspartic Acid; Case-Control Studies; Cysteine; Double-Blind Method; Female; Ferritins; Genetic Predisposition to Disease; Genetic Testing; Genotype; Hemochromatosis; Hispanic or Latino; Histidine; Homozygote; Humans; Male; Middle Aged; Mutation; Prevalence; Surveys and Questionnaires; Transferrin; Tyrosine; United States; White People | 2002 |
An essential role of N-terminal arginylation in cardiovascular development.
Topics: Alkylation; Aminoacyltransferases; Animals; Aorta; Arginine; Aspartic Acid; Blood Vessels; Cell Line; Cysteic Acid; Cysteine; Female; Glutamic Acid; Heart; Heart Defects, Congenital; Heart Septal Defects; Hypoxia-Inducible Factor 1, alpha Subunit; Male; Mice; Mice, Inbred C57BL; Neovascularization, Physiologic; Oxidation-Reduction; Proteins; Pulmonary Artery; Recombinant Proteins; RGS Proteins; Sulfinic Acids; Transcription Factors; Transfection | 2002 |
A novel approach to the synthesis of EGF-like domains: a method for the one-pot regioselective formation of the three disulfide bonds of a human blood coagulation factor VII EGF-1 analogue.
Topics: Amino Acid Sequence; Aspartic Acid; Chromatography, High Pressure Liquid; Circular Dichroism; Cysteine; Disulfides; Epidermal Growth Factor; Factor VII; Humans; Molecular Sequence Data; Peptides; Protein Folding; Protein Structure, Secondary; Protein Structure, Tertiary; Sequence Homology, Amino Acid; Spectrometry, Mass, Electrospray Ionization; Structure-Activity Relationship | 2002 |
Distribution of mutations in human thymidylate synthase yielding resistance to 5-fluorodeoxyuridine.
Topics: Amino Acid Sequence; Antimetabolites, Antineoplastic; Arginine; Aspartic Acid; Binding Sites; Cell Line; Cloning, Molecular; Cysteine; DNA, Complementary; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Escherichia coli; Floxuridine; Gene Library; Humans; Kinetics; Models, Genetic; Models, Molecular; Molecular Sequence Data; Mutation; Polymerase Chain Reaction; Protein Binding; Sequence Homology, Amino Acid; Thymidylate Synthase | 2002 |
Biosynthesis, intracellular targeting, and degradation of the EAAC1 glutamate/aspartate transporter in C6 glioma cells.
Topics: Amino Acid Transport System X-AG; Animals; Aspartic Acid; Biological Transport; Cell Line; Cell Membrane; Cysteine; Excitatory Amino Acid Transporter 3; Glutamate Plasma Membrane Transport Proteins; Glutamates; Glycosylation; Methionine; Radioisotopes; Rats; Symporters | 2002 |
Aminoacylation of the N-terminal cysteine is essential for Lol-dependent release of lipoproteins from membranes but does not depend on lipoprotein sorting signals.
Topics: Acylation; Aspartic Acid; ATP-Binding Cassette Transporters; Bacterial Outer Membrane Proteins; Cysteine; Escherichia coli; Escherichia coli Proteins; Lipoproteins; Mass Spectrometry; Membrane Proteins; Periplasmic Binding Proteins; Plasmids; Recombinant Proteins; Signal Transduction | 2002 |
Binding of D- and L-captopril inhibitors to metallo-beta-lactamase studied by polarizable molecular mechanics and quantum mechanics.
Topics: Algorithms; Aspartic Acid; Bacteroides fragilis; beta-Lactamase Inhibitors; beta-Lactamases; Binding Sites; Captopril; Computational Biology; Cysteine; Enzyme Inhibitors; Histidine; Models, Molecular; Molecular Structure; Protein Conformation; Serine; Static Electricity; Stereoisomerism; Zinc | 2002 |
Anionic substitutes for catalytic aspartic acids in phosphoribulokinase.
Topics: Adenosine Triphosphate; Amino Acid Substitution; Anions; Aspartic Acid; Catalytic Domain; Cysteine; Fluorescent Dyes; Kinetics; Models, Molecular; Mutagenesis; NAD; Phosphotransferases (Alcohol Group Acceptor); Protein Conformation; Recombinant Proteins | 2002 |
Crystal structure of microbial transglutaminase from Streptoverticillium mobaraense.
Topics: Amino Acid Sequence; Aspartic Acid; Binding Sites; Catalysis; Cross-Linking Reagents; Crystallography, X-Ray; Cysteine; Escherichia coli; Histidine; Models, Chemical; Models, Molecular; Molecular Sequence Data; Protein Structure, Tertiary; Streptomyces; Structure-Activity Relationship; Transglutaminases | 2002 |
Conserved residues in the putative catalytic triad of human bile acid Coenzyme A:amino acid N-acyltransferase.
Topics: Acyl Coenzyme A; Acyltransferases; Amino Acid Sequence; Aspartic Acid; Bile Acids and Salts; Catalysis; Catalytic Domain; Cholic Acids; Coenzyme A; Conserved Sequence; Cysteine; DNA, Complementary; Dose-Response Relationship, Drug; Ethylmaleimide; Histidine; Humans; Kinetics; Models, Chemical; Molecular Sequence Data; Mutation; Protein Binding; Sequence Homology, Amino Acid; Spectrometry, Mass, Electrospray Ionization; Time Factors; Trypsin | 2002 |
Stabilization of the R allosteric structure of Escherichia coli aspartate transcarbamoylase by disulfide bond formation.
Topics: Adenosine Triphosphate; Alanine; Allosteric Site; Aspartate Carbamoyltransferase; Aspartic Acid; Catalysis; Catalytic Domain; Cross-Linking Reagents; Cysteine; Cytidine Triphosphate; Disulfides; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Escherichia coli; Kinetics; Models, Molecular; Mutation; Protein Binding; Protein Structure, Quaternary; Scattering, Radiation; X-Rays | 2002 |
A positive charge preservation at position 116 of alpha A-crystallin is critical for its structural and functional integrity.
Topics: Alcohol Dehydrogenase; alpha-Crystallin A Chain; alpha-Glucosidases; Animals; Arginine; Aspartic Acid; Circular Dichroism; Cysteine; Glycine; Humans; Lysine; Molecular Weight; Mutagenesis, Site-Directed; Protein Conformation; Protein Denaturation; Protein Folding; Protein Structure, Secondary; Rats; Static Electricity; Urea | 2002 |
Revisiting monomeric HIV-1 protease. Characterization and redesign for improved properties.
Topics: Amino Acid Sequence; Amino Acid Substitution; Arginine; Aspartic Acid; Cysteine; Dimerization; Disulfides; Enzyme Stability; Genetic Variation; HIV Protease; Kinetics; Magnetic Resonance Spectroscopy; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Protein Conformation; Protein Folding; Recombinant Proteins; Sequence Alignment; Sequence Homology, Amino Acid | 2003 |
The third activity for lysyl hydroxylase 3: galactosylation of hydroxylysyl residues in collagens in vitro.
Topics: Amino Acid Sequence; Animals; Aspartic Acid; Cell Line; Cysteine; Drug Residues; Enzymes; Galactose; Galactosyltransferases; Humans; Hydroxylysine; Insecta; Mutation; Procollagen-Lysine, 2-Oxoglutarate 5-Dioxygenase | 2002 |
Chemical cleavage of polypeptides.
Topics: Asparagine; Aspartic Acid; Cysteine; Glycine; Methionine; Peptides; Sequence Analysis, Protein; Tryptophan | 2003 |
Association between hemochromatosis (HFE) gene mutation carrier status and the risk of colon cancer.
Topics: Age Factors; Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspartic Acid; Case-Control Studies; Colonic Neoplasms; Cysteine; Feeding Behavior; Female; Hemochromatosis Protein; Heterozygote; Histidine; Histocompatibility Antigens Class I; Humans; Iron Compounds; Male; Meat; Membrane Proteins; Middle Aged; Mutation; North Carolina; Risk Assessment; Risk Factors; Tyrosine | 2003 |
Binding of ATP as well as tetrahydrofolate induces conformational changes in Lactobacillus casei folylpolyglutamate synthetase in solution.
Topics: Adenosine Triphosphate; Aspartic Acid; Circular Dichroism; Cyclic N-Oxides; Cysteine; Electron Spin Resonance Spectroscopy; Lacticaseibacillus casei; Lysine; Mesylates; Mutagenesis, Site-Directed; Peptide Synthases; Protein Binding; Protein Conformation; Solutions; Spin Labels; Substrate Specificity; Tetrahydrofolates | 2003 |
Development of an efficient "substrate-trapping" mutant of Src homology phosphotyrosine phosphatase 2 and identification of the epidermal growth factor receptor, Gab1, and three other proteins as target substrates.
Topics: 3T3 Cells; Adaptor Proteins, Signal Transducing; Alanine; Animals; Aspartic Acid; Cell Line; COS Cells; Cysteine; ErbB Receptors; Helminth Proteins; Humans; Immunoblotting; Mice; Microscopy, Fluorescence; Mutagenesis, Site-Directed; Mutation; Phosphoproteins; Phosphoric Monoester Hydrolases; Phosphorylation; Plasmids; Precipitin Tests; Protein Binding; Protein Structure, Tertiary; Serine; Signal Transduction; src Homology Domains; Transfection | 2003 |
An opsin mutant with increased thermal stability.
Topics: Amino Acid Sequence; Animals; Asparagine; Aspartic Acid; Cattle; COS Cells; Cross-Linking Reagents; Cysteine; Disulfides; Dithiothreitol; Light; Molecular Sequence Data; Mutagenesis, Site-Directed; Protein Denaturation; Recombinant Proteins; Retinaldehyde; Rhodopsin; Thermodynamics; Transducin; Transfection | 2003 |
The glutamate transporters EAAT2 and EAAT3 mediate cysteine uptake in cortical neuron cultures.
Topics: Amino Acid Transport System X-AG; Animals; Aspartic Acid; Astrocytes; Binding, Competitive; Biological Transport; Cells, Cultured; Cerebral Cortex; Cysteine; Dose-Response Relationship, Drug; Excitatory Amino Acid Transporter 1; Excitatory Amino Acid Transporter 2; Excitatory Amino Acid Transporter 3; Glutamate Plasma Membrane Transport Proteins; Glutamic Acid; Glutathione; Kainic Acid; Mice; Neurons; Sodium; Symporters | 2003 |
Mapping out regions on the surface of the aspartate receptor that are essential for kinase activation.
Topics: Aspartic Acid; Chemotaxis; Cysteine; Cytoplasm; Dimerization; Enzyme Activation; Ethylmaleimide; Fluoresceins; Fluorescent Dyes; Models, Molecular; Mutagenesis, Site-Directed; Peptide Library; Protein Interaction Mapping; Protein Kinases; Protein Structure, Tertiary; Receptors, Amino Acid; Rhodamines; Salmonella typhimurium; Surface Properties | 2003 |
Modeling zinc in biomolecules with the self consistent charge-density functional tight binding (SCC-DFTB) method: applications to structural and energetic analysis.
Topics: Alcohol Dehydrogenase; Algorithms; Aminopeptidases; Aspartic Acid; Bacterial Proteins; Binding Sites; Carbonic Anhydrases; Cysteine; Glutamic Acid; Histidine; Liver; Models, Molecular; Molecular Conformation; Protein Binding; Protein Conformation; Water; Zinc | 2003 |
Characterization of aspartate aminotransferase from the cyanobacterium Phormidium lapideum.
Topics: Amino Acid Sequence; Amino Acids; Aspartate Aminotransferases; Aspartic Acid; Catalysis; Cyanobacteria; Cysteine; Enzyme Stability; Hot Temperature; Hydrogen-Ion Concentration; Ketoglutaric Acids; Kinetics; Molecular Sequence Data; Neurotransmitter Agents; Sequence Homology, Amino Acid | 2003 |
Analysis of TP53 and PTEN in gliomatosis cerebri.
Topics: Adolescent; Adult; Aged; Amino Acid Substitution; Arginine; Aspartic Acid; Brain; Cell Line; Cysteine; DNA Mutational Analysis; Female; Glycine; Humans; Immunohistochemistry; Loss of Heterozygosity; Magnetic Resonance Imaging; Male; Middle Aged; Mutation; Neoplasms, Neuroepithelial; Phosphoric Monoester Hydrolases; Polymorphism, Single-Stranded Conformational; PTEN Phosphohydrolase; Reverse Transcriptase Polymerase Chain Reaction; Tumor Suppressor Protein p53; Tumor Suppressor Proteins | 2003 |
CCHX zinc finger derivatives retain the ability to bind Zn(II) and mediate protein-DNA interactions.
Topics: Amino Acid Sequence; Animals; Aspartic Acid; Circular Dichroism; Cysteine; DNA; DNA-Binding Proteins; Dose-Response Relationship, Drug; Histidine; Humans; Kinetics; Magnetic Resonance Spectroscopy; Models, Molecular; Molecular Sequence Data; Mutation; Plasmids; Protein Binding; Protein Conformation; Protein Folding; Protein Structure, Tertiary; Sequence Homology, Amino Acid; Spectrophotometry, Atomic; Ultracentrifugation; Ultraviolet Rays; Zinc; Zinc Fingers | 2003 |
Population screening for hemochromatosis: a study in 5370 Spanish blood donors.
Topics: Adult; Aspartic Acid; Blood Donors; Cysteine; Female; Ferritins; Gene Frequency; Genetic Testing; Genotype; Hemochromatosis; Hemochromatosis Protein; Heterozygote; Histidine; Histocompatibility Antigens Class I; Homozygote; Humans; Male; Membrane Proteins; Middle Aged; Mutation; Sex Characteristics; Spain; Transferrin; Tyrosine | 2003 |
Negative charges in the transmembrane domains of the HERG K channel are involved in the activation- and deactivation-gating processes.
Topics: Amino Acid Sequence; Animals; Aspartic Acid; Cation Transport Proteins; Cysteine; Electrophysiology; Ether-A-Go-Go Potassium Channels; Ion Channel Gating; Membrane Potentials; Molecular Sequence Data; Mutagenesis, Site-Directed; Oocytes; Potassium Channels; Potassium Channels, Voltage-Gated; Xenopus | 2003 |
Two homozygous mutations in the 11 beta-hydroxysteroid dehydrogenase type 2 gene in a case of apparent mineralocorticoid excess.
Topics: 11-beta-Hydroxysteroid Dehydrogenase Type 2; Animals; Asparagine; Aspartic Acid; Base Sequence; Child, Preschool; CHO Cells; Cricetinae; Cysteine; Homozygote; Humans; Hydroxysteroid Dehydrogenases; Male; Mineralocorticoids; Models, Molecular; Mutation; Polymorphism, Single Nucleotide; Threonine | 2003 |
The human bile acid-CoA:amino acid N-acyltransferase functions in the conjugation of fatty acids to glycine.
Topics: Acyltransferases; Amino Acid Sequence; Animals; Aspartic Acid; Bile Acids and Salts; Catalysis; Cloning, Molecular; Cysteine; Cytosol; DNA, Complementary; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Fatty Acids; Fibroblasts; Gallbladder; Glycine; Green Fluorescent Proteins; Histidine; Humans; Intestines; Kinetics; Liver; Luminescent Proteins; Mass Spectrometry; Mice; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; Recombinant Fusion Proteins; Recombinant Proteins; Taurine; Tissue Distribution | 2003 |
A highly conserved aspartic acid residue in the signature disulfide loop of the alpha 1 subunit is a determinant of gating in the glycine receptor.
Topics: Amino Acid Motifs; Amino Acid Sequence; Aspartic Acid; Cell Line; Chlorine; Cysteine; Disulfides; DNA, Complementary; Dose-Response Relationship, Drug; Electrophysiology; Genetic Vectors; Glycine; Humans; Hydrogen-Ion Concentration; Ion Channels; Lysine; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; Protein Structure, Tertiary; Receptors, Glycine; Taurine | 2003 |
Molecular motions of the outer ring of charge of the sodium channel: do they couple to slow inactivation?
Topics: Amino Acid Substitution; Animals; Aspartic Acid; Cysteine; Electrophysiology; Glutamic Acid; Ion Channel Gating; Molecular Conformation; Muscle, Skeletal; Mutation; Oocytes; Phenanthrolines; Rats; Sodium Channels; Xenopus laevis | 2003 |
Structure of the Escherichia coli malate synthase G:pyruvate:acetyl-coenzyme A abortive ternary complex at 1.95 A resolution.
Topics: Acetyl Coenzyme A; Arginine; Aspartic Acid; Binding Sites; Candida albicans; Crystallography, X-Ray; Cysteine; Escherichia coli; Kinetics; Malate Synthase; Models, Chemical; Models, Molecular; Mutagenesis; Mycobacterium tuberculosis; Oxidation-Reduction; Protein Binding; Protein Conformation; Protein Isoforms; Pyruvic Acid; Sulfenic Acids; X-Rays | 2003 |
Aspolin, a novel extremely aspartic acid-rich protein in fish muscle, promotes iron-mediated demethylation of trimethylamine-N-oxide.
Topics: Aldehyde-Lyases; Amino Acid Sequence; Animals; Aspartic Acid; Base Sequence; Cloning, Molecular; Cysteine; DNA, Complementary; Fish Proteins; Fishes; Formaldehyde; Hydrogen-Ion Concentration; Iron; Methylamines; Models, Chemical; Molecular Sequence Data; Muscle Proteins; Muscle, Skeletal; Protein Precursors; Protein Structure, Tertiary; RNA, Messenger; Sequence Homology, Amino Acid; Time Factors; Tissue Distribution | 2003 |
[Study on the decarboxylation of L-cysteinesulfinic acid, L-cysteic acid, and L-glutamic acid by various organs of rabbits; influence of pyridoxal phosphate and thiol groups].
Topics: Animals; Aspartic Acid; Biochemical Phenomena; Coenzymes; Cysteic Acid; Cysteine; Decarboxylation; Glutamates; Glutamic Acid; Pyridoxal Phosphate; Rabbits; Sulfhydryl Compounds | 1956 |
The chromatographic determination of glutamic, aspartic, and cysteic acids using and anion exchange resin.
Topics: Anion Exchange Resins; Aspartic Acid; Chromatography; Cysteic Acid; Cysteine; Glutamates | 1957 |
S-methyl-L-cysteine sulphoxide: an inhibitor of aspartic acid utilization in Leuconostoc mesenteroides.
Topics: Aspartic Acid; Cysteine; Leuconostoc; Safrole; Sulfoxides | 1960 |
Amino acids, amino sugars and sugars present in the cell wall of some strains of Streptococcus pyogenes.
Topics: Alanine; Amino Acids; Amino Sugars; Arginine; Aspartic Acid; Cell Wall; Cysteine; Glucosamine; Glutamates; Glycine; Hexosamines; Isoleucine; Leucine; Lysine; Serine; Streptococcus pyogenes; Threonine; Valine | 1962 |
Independence of amounts of incorporation of amino-acids into histones on the aminoacid composition of these proteins.
Topics: Amino Acids; Aspartic Acid; Cysteine; Histones; Lysine; Methionine; Proteins | 1963 |
GAS CHROMATOGRAPHY OF THE METHYL ESTERS OF THE AMINO ACIDS AS THE FREE BASE AND BY DISSOCIATION OF THEIR ACID SALTS.
Topics: Acetates; Amino Acids; Aspartic Acid; Chlorides; Chromatography; Chromatography, Gas; Cysteine; Cystine; Esters; Hydroxyproline; Ion Exchange Resins; Leucine; Lysine; Phenylalanine; Proline; Research; Salts; Serine | 1963 |
[RESEARCH ON THE NUTRITION OF ERWINIA CAROTOVORA].
Topics: Alanine; Aminobutyrates; Ammonium Compounds; Arginine; Asparagine; Aspartic Acid; Boron; Calcium; Cobalt; Copper; Creatine; Creatinine; Culture; Culture Media; Cysteine; Cystine; Erwinia; Glutamates; Glycine; Iron; Lysine; Magnesium; Manganese; Methionine; Minerals; Molybdenum; Pectobacterium carotovorum; Proteins; Quaternary Ammonium Compounds; Tryptophan; Tyrosine; Zinc | 1963 |
[THE DEAMINATION OF SEVERAL AMINO ACIDS IN THE LIVER OF EMBRYOS DURING THE TRANSITION FROM UREOTELISM TO URICOTELISM].
Topics: Amino Acids; Aspartic Acid; Chick Embryo; Cysteine; Deamination; Glutamates; Histidine; Hydroxylamines; Liver; Ornithine; Pharmacology; Proteins; Research; Urea; Uric Acid; Valine | 1963 |
STUDIES ON COLLETOTRICHUM CAPSICI III. THE EFFECT OF INITIAL PH ON THE GROWTH AND AMINO ACID COMPOSITION.
Topics: Alanine; Amino Acids; Aminobutyrates; Arginine; Aspartic Acid; Chromatography; Colletotrichum; Cysteine; Fungi; Glutamates; Glutamine; Glycine; Histidine; Hydrogen-Ion Concentration; Isoleucine; Leucine; Phenylalanine; Research; Serine; Tyrosine | 1963 |
ASPECTS OF CHEMORECEPTION IN CRUSTACEA.
Topics: Aminobutyrates; Animals; Aspartic Acid; Crustacea; Cysteine; Electrophysiology; Glutamates; Glutathione; Glycine; Glycogen; Histamine; Indoles; Leucine; Methionine; Muscles; Pharmacology; Research; Sensory Receptor Cells; Serine; Tyrosine; Urea | 1963 |
BIOSYNTHESIS OF BACITRACIN. I. FORMATION OF BACITRACIN BY A SUBCELLULAR FRACTION OF BACILLUS LICHENIFORMIS.
Topics: Asparagine; Aspartic Acid; Bacillus; Bacitracin; Carbon Isotopes; Chromatography; Cysteine; Cystine; Glutamates; Glutathione; Histidine; Isoleucine; Lysine; Metabolism; Micrococcus; Ornithine; Phenylalanine; Research; Subcellular Fractions; Sulfhydryl Compounds; Sulfur Isotopes | 1964 |
NUTRITIONAL FACTORS RELATING TO GROWTH AND OXYTETRACYCLINE FORMATION BY STREPTOMYCES RIMOSUS.
Topics: Alanine; Amino Acids; Arginine; Aspartic Acid; Culture Media; Cysteine; Cystine; Glutamine; Glycine; Histidine; Isoleucine; Lysine; Metabolism; Methionine; Oxytetracycline; Research; Serine; Streptomyces; Streptomyces rimosus | 1964 |
DIVALENT METAL ION ACTIVATION OF BETA-METHYLASPARTASE.
Topics: Ammonia; Ammonia-Lyases; Aspartic Acid; Benzoates; Cadmium; Calcium; Cations, Divalent; Chemical Phenomena; Chemistry, Physical; Clostridium; Cobalt; Copper; Cysteine; Fumarates; Ions; Iron; Lyases; Magnesium; Manganese; Nickel; Pharmacology; Research; Spectrophotometry; Zinc | 1964 |
SOME IN VITRO STUDIES OF POLONIUM-210 BINDING BY BLOOD CONSTITUENTS.
Topics: Amino Acids; Aspartic Acid; Bicarbonates; Blood; Citrates; Cysteine; Glutamates; Glycine; Histidine; Hydrogen-Ion Concentration; Imidazoles; In Vitro Techniques; Malates; Metabolism; Phosphates; Polonium; Research; Serine; Tryptophan | 1964 |
ENZYMATIC DESULFINATION OF CYSTEINE SULFINIC ACID.
Topics: Alanine; Alcaligenes; Aspartic Acid; Biochemical Phenomena; Biochemistry; Carboxy-Lyases; Cysteine; Keto Acids; Ketoglutaric Acids; Pyridoxal Phosphate; Research; Sulfites | 1964 |
METABOLIC PRODUCTS IN PIGEON TISSUES AFTER FEEDING GLUCOSE.
Topics: Alanine; Animals; Arginine; Aspartic Acid; Birds; Carbohydrate Metabolism; Carbon Isotopes; Columbidae; Cysteine; Dietary Carbohydrates; Fructose; Glucose; Glutamates; Lactates; Muscles; Myocardium; Research | 1964 |
GAS CHROMATOGRAPHY OF VOLATILE AMINO ACID DERIVATIVES. II. LEUCINE, CYSTEINE, PROLINE, HYDROXYPROLINE, METHIONINE, PHENYLALANINE, ASPARTIC ACID AND GLUTAMIC ACID.
Topics: Arginine; Aspartic Acid; Chromatography; Chromatography, Gas; Cysteine; Glutamates; Glutamic Acid; Hydroxyproline; Leucine; Methionine; Phenylalanine; Proline; Research | 1965 |
ACTION OF GLUTAMIC ACID AND OTHER NATURALLY OCCURRING AMINO-ACIDS ON SNAIL CENTRAL NEURONS.
Topics: Acetylcholine; Amino Acids; Aminobutyrates; Animals; Aspartic Acid; Cysteine; Electrophysiology; Glutamates; Glutamic Acid; Helix, Snails; Iontophoresis; Neural Conduction; Neurons; Pharmacology; Research; Sensory Receptor Cells; Snails | 1964 |
The crystal structure of Escherichia coli heat shock protein YedU reveals three potential catalytic active sites.
Topics: Amino Acid Motifs; Amino Acid Sequence; Aspartic Acid; Binding Sites; Catalytic Domain; Crystallography, X-Ray; Cysteine; Dimerization; Electronic Data Processing; Escherichia coli Proteins; Glutamic Acid; Heat-Shock Proteins; Histidine; Hydrophobic and Hydrophilic Interactions; Models, Molecular; Molecular Chaperones; Molecular Sequence Data; Protein Structure, Quaternary; Protein Structure, Tertiary; Recombinant Proteins; Sequence Homology, Amino Acid; Structural Homology, Protein; Zinc | 2003 |
Non-active site residues Cys69 and Asp150 affected the enzymatic properties of glutathione S-transferase AdGSTD3-3.
Topics: Amino Acid Motifs; Amino Acid Substitution; Animals; Anopheles; Aspartic Acid; Binding Sites; Catalysis; Cysteine; Dimerization; Enzyme Inhibitors; Enzyme Stability; Glutathione Transferase; Isoenzymes; Kinetics; Models, Molecular; Mutagenesis, Site-Directed; Protein Structure, Tertiary; Recombinant Proteins; Substrate Specificity | 2003 |
Aqueous access pathways in subunit a of rotary ATP synthase extend to both sides of the membrane.
Topics: Adenosine Triphosphate; Aspartic Acid; Biological Transport; Cell Membrane; Cysteine; Cystine; Cytoplasm; Escherichia coli; Ethylmaleimide; Models, Molecular; Mutation; Protein Structure, Tertiary; Proton-Translocating ATPases; Protons; Silver; Temperature; Time Factors | 2003 |
Lecithin retinol acyltransferase is a founder member of a novel family of enzymes.
Topics: Amino Acid Sequence; Aspartic Acid; Binding Sites; Catalytic Domain; Conserved Sequence; Cysteine; Cysteine Endopeptidases; Glutamine; Histidine; Humans; Molecular Sequence Data; Multigene Family; Mutagenesis, Site-Directed; Phosphatidylcholine-Sterol O-Acyltransferase | 2003 |
Defining the bacteriophage T4 DNA packaging machine: evidence for a C-terminal DNA cleavage domain in the large terminase/packaging protein gp17.
Topics: Adenosine Triphosphatases; Amino Acid Sequence; Aspartic Acid; Bacteriophage T4; Binding Sites; Cysteine; DNA; Endodeoxyribonucleases; Histidine; Molecular Sequence Data; Mutation; Sequence Alignment; Viral Proteins | 2003 |
Role of His-16 in turnover of T4 pyrimidine dimer glycosylase.
Topics: Alanine; Aspartic Acid; Cell Survival; Cysteine; Dimerization; DNA; DNA Glycosylases; DNA Repair; Escherichia coli; Glutamic Acid; Histidine; Kinetics; Lysine; Models, Biological; Mutagenesis, Site-Directed; Mutation; Oligonucleotides; Phenotype; Plasmids; Serine; Time Factors; Ultraviolet Rays | 2004 |
Treponema denticola cystalysin catalyzes beta-desulfination of L-cysteine sulfinic acid and beta-decarboxylation of L-aspartate and oxalacetate.
Topics: Animals; Aspartic Acid; Carboxy-Lyases; Catalysis; Cattle; Cystathionine gamma-Lyase; Cysteine; Decarboxylation; Kinetics; Neurotransmitter Agents; Oxaloacetates; Pyridoxal Phosphate; Pyruvic Acid; Rabbits; Spectrophotometry; Treponema | 2003 |
Role of neuronal glutamate transporter in the cysteine uptake and intracellular glutathione levels in cultured cortical neurons.
Topics: Amino Acid Transport System X-AG; Animals; Aspartic Acid; Blotting, Western; Cells, Cultured; Cerebral Cortex; Chromatography, High Pressure Liquid; Cysteine; Embryo, Mammalian; Excitatory Amino Acid Antagonists; Extracellular Fluid; Glutamic Acid; Glutathione; Immunohistochemistry; Neurons; Rats; Sodium | 2003 |
Effect of pH on the oxidation-reduction properties of thioredoxins.
Topics: Alanine; Animals; Aspartic Acid; Binding Sites; Chlamydomonas reinhardtii; Cysteine; Disulfides; Electron Transport; Escherichia coli Proteins; Hydrogen-Ion Concentration; Mutagenesis, Site-Directed; Oxidation-Reduction; Protons; Thioredoxin h; Thioredoxins; Tryptophan | 2003 |
Prevalence of the Y165C, G382D and 1395delGGA germline mutations of the MYH gene in Italian patients with adenomatous polyposis coli and colorectal adenomas.
Topics: Adenine; Adenoma; Adenomatous Polyposis Coli; Adult; Aged; Aspartic Acid; Case-Control Studies; Colorectal Neoplasms; Cysteine; DNA Glycosylases; DNA Mutational Analysis; DNA, Neoplasm; Female; Gene Deletion; Gene Frequency; Germ-Line Mutation; Glycine; Guanine; Humans; Italy; Male; Middle Aged; Tyrosine | 2004 |
L-Glutamate in the extracellular space regulates endogenous D-aspartate homeostasis in rat pheochromocytoma MPT1 cells.
Topics: Amino Acid Transport System X-AG; Animals; Aspartic Acid; Cell Line, Tumor; Cysteine; Extracellular Space; Glutamic Acid; Homeostasis; Neurotransmitter Agents; PC12 Cells; Pheochromocytoma; Rats | 2004 |
Evidence for the proximity of the extreme N-terminus of the neurokinin-2 (NK2) tachykinin receptor to Cys167 in the putative fourth transmembrane helix.
Topics: Amino Acid Sequence; Animals; Aspartic Acid; Benzamides; Binding Sites; Binding, Competitive; CHO Cells; Cricetinae; Cysteine; Ethyl Methanesulfonate; Extracellular Space; Glutamic Acid; Humans; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Peptide Fragments; Piperidines; Protein Structure, Secondary; Receptors, Neurokinin-2; Static Electricity; Sulfhydryl Reagents; Tritium | 2004 |
Escherichia coli thioredoxin inhibition by cadmium: two mutually exclusive binding sites involving Cys32 and Asp26.
Topics: Aspartic Acid; Binding Sites; Cadmium; Calorimetry; Calorimetry, Differential Scanning; Cysteine; Escherichia coli; Hot Temperature; Hydrogen-Ion Concentration; Insulin; Kinetics; Mass Spectrometry; Metals; Models, Molecular; Oxygen; Protein Binding; Spectrometry, Fluorescence; Spectrophotometry; Spectroscopy, Fourier Transform Infrared; Temperature; Thermodynamics; Thioredoxins; Time Factors; Tryptophan | 2004 |
Subunit interaction and regulation of activity through terminal domains of the family D DNA polymerase from Pyrococcus horikoshii.
Topics: Amino Acid Motifs; Amino Acid Sequence; Archaeal Proteins; Aspartic Acid; Catalysis; Chromatography, Gel; Cysteine; Dimerization; DNA; DNA Replication; DNA-Directed DNA Polymerase; DNA, Archaeal; Exonucleases; Gene Deletion; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; Phenotype; Protein Structure, Tertiary; Pyrococcus horikoshii; Recombinant Proteins; Sequence Homology, Amino Acid; Zinc Fingers | 2004 |
Domain structures and roles in bacteriophage HK97 capsid assembly and maturation.
Topics: Asparagine; Aspartic Acid; Capsid; Coliphages; Crystallization; Cysteine; Glutamic Acid; Lysine; Protein Precursors; Protein Structure, Secondary; Protein Structure, Tertiary; Protein Subunits; Spectrum Analysis, Raman; Tryptophan; Tyrosine; Virus Assembly | 2004 |
Frequency of the C282Y and H63D mutations of the hemochromatosis gene (HFE) in 2501 ethnic Danes.
Topics: Aspartic Acid; Confidence Intervals; Cysteine; Denmark; Female; Gene Frequency; Genotype; Hemochromatosis; Hemochromatosis Protein; Histidine; Histocompatibility Antigens Class I; Humans; Male; Membrane Proteins; Mutation; Tyrosine | 2004 |
HFE gene and hemochromatosis.
Topics: Aspartic Acid; Cysteine; Gene Frequency; Hemochromatosis; Hemochromatosis Protein; Heterozygote; Histidine; Histocompatibility Antigens Class I; Homozygote; Humans; Membrane Proteins; Mutation; Mutation, Missense; Tyrosine | 2004 |
Potyviral NIa proteinase, a proteinase with novel deoxyribonuclease activity.
Topics: Aspartic Acid; Cell Nucleus; Cysteine; Cytoplasm; Deoxyribonucleases; DNA; DNA Mutational Analysis; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Endopeptidases; Escherichia coli; Glutathione Transferase; Green Fluorescent Proteins; Histidine; Hydrogen-Ion Concentration; Ions; Kinetics; Luminescent Proteins; Magnesium; Models, Molecular; Mutation; Plasmids; Point Mutation; Potyvirus; Recombinant Fusion Proteins; Recombinant Proteins; Sodium Chloride; Solanum tuberosum; Time Factors; Viral Proteins | 2004 |
The structure and mechanism of serine acetyltransferase from Escherichia coli.
Topics: Acetylation; Acetyltransferases; Amino Acid Sequence; Aspartic Acid; Bacterial Proteins; Binding Sites; Catalysis; Crystallography, X-Ray; Cysteine; Escherichia coli; Histidine; Models, Molecular; Molecular Sequence Data; Protein Conformation; Protein Structure, Secondary; Sequence Homology, Amino Acid; Serine O-Acetyltransferase | 2004 |
The fourth transmembrane domain of the Helicobacter pylori Na+/H+ antiporter NhaA faces a water-filled channel required for ion transport.
Topics: Alanine; Amino Acid Sequence; Antiporters; Aspartic Acid; Binding Sites; Cell Membrane; Cysteine; Cytoplasm; DNA; Escherichia coli; Escherichia coli Proteins; Ethylmaleimide; Helicobacter pylori; Ion Transport; Ions; Kinetics; Leucine; Lithium; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; Phenylalanine; Plasmids; Protein Binding; Protein Conformation; Protein Structure, Secondary; Protein Structure, Tertiary; Protons; Serine; Sodium-Hydrogen Exchangers; Threonine; Valine; Water | 2004 |
Crystal structure of a bacterial type III polyketide synthase and enzymatic control of reactive polyketide intermediates.
Topics: Acyltransferases; Asparagine; Aspartic Acid; Binding Sites; Catalysis; Catalytic Domain; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Codon; Crystallography, X-Ray; Cysteine; Escherichia coli; Evolution, Molecular; Hydrogen-Ion Concentration; Magnetic Resonance Spectroscopy; Models, Chemical; Models, Molecular; Mutagenesis, Site-Directed; Mutation; Naphthols; Naphthoquinones; Oxalic Acid; Polyketide Synthases; Protein Conformation; Protein Structure, Tertiary; Serine; Streptomyces; Streptomyces coelicolor | 2004 |
Crystal structure of the cytochrome p450cam mutant that exhibits the same spectral perturbations induced by putidaredoxin binding.
Topics: Aspartic Acid; Binding Sites; Camphor; Camphor 5-Monooxygenase; Carbon Monoxide; Crystallography, X-Ray; Cysteine; Cystine; Electrons; Escherichia coli; Ferredoxins; Leucine; Magnetic Resonance Spectroscopy; Models, Molecular; Mutation; Protein Binding; Protein Conformation; Temperature; Threonine | 2004 |
Alanine-scanning mutagenesis in the signature disulfide loop of the glycine receptor alpha 1 subunit: critical residues for activation and modulation.
Topics: Alanine; Allosteric Regulation; Amino Acid Sequence; Amino Acid Substitution; Aspartic Acid; Cell Line; Conserved Sequence; Cysteine; Disulfides; Humans; Leucine; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Phenylalanine; Proline; Protein Structure, Tertiary; Protein Subunits; Receptors, Glycine; Tryptophan | 2004 |
Crystal structure of a family 54 alpha-L-arabinofuranosidase reveals a novel carbohydrate-binding module that can bind arabinose.
Topics: Amino Acid Motifs; Amino Acid Sequence; Arabinose; Aspartic Acid; Aspergillus; Binding Sites; Carbohydrates; Catalytic Domain; Cloning, Molecular; Crystallography, X-Ray; Cysteine; Disulfides; DNA Mutational Analysis; Electrons; Glutamic Acid; Glycoside Hydrolases; Kinetics; Models, Molecular; Molecular Sequence Data; Multigene Family; Mutagenesis, Site-Directed; Protein Binding; Protein Folding; Protein Structure, Secondary; Protein Structure, Tertiary; Sequence Homology, Amino Acid | 2004 |
Only a portion of the small seatbelt loop in human choriogonadotropin appears capable of contacting the lutropin receptor.
Topics: Amino Acid Sequence; Animals; Arginine; Aspartic Acid; Carbon; Chorionic Gonadotropin; COS Cells; Cross-Linking Reagents; Cysteine; Dimerization; Disulfides; Dose-Response Relationship, Drug; Follicle Stimulating Hormone; Humans; Hydrogen-Ion Concentration; Ligands; Luteinizing Hormone; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; Protein Binding; Protein Structure, Tertiary; Radioimmunoassay; Receptors, Thyrotropin; Serine; Signal Transduction; Temperature; Threonine | 2004 |
The effect of sugar, amino acid, metal ion, and NaCl on model Maillard reaction under pH control.
Topics: Alanine; Amino Acids; Arabinose; Arginine; Aspartic Acid; Biochemistry; Carbohydrates; Colorimetry; Copper; Cysteine; Fructose; Glucose; Glutamic Acid; Glycine max; Hot Temperature; Hydrogen-Ion Concentration; Ions; Iron; Isoleucine; Leucine; Lysine; Maltose; Metals; Models, Chemical; Phenylalanine; Proline; Serine; Sodium Chloride; Temperature; Time Factors; Valine; Xylose | 2004 |
Long-range allosteric transitions in carbamoyl phosphate synthetase.
Topics: Adenosine Diphosphate; Allosteric Site; Aspartic Acid; Binding Sites; Carbamoyl-Phosphate Synthase (Glutamine-Hydrolyzing); Crystallography, X-Ray; Cysteine; Escherichia coli Proteins; Magnesium; Models, Molecular; Mutagenesis, Site-Directed; Ornithine; Protein Conformation; Protein Subunits; Uridine Monophosphate | 2004 |
DNA cross-linking by dehydromonocrotaline lacks apparent base sequence preference.
Topics: Amino Acids; Aspartic Acid; Base Sequence; Chromatography, High Pressure Liquid; Cross-Linking Reagents; Cysteine; DNA; Electrophoretic Mobility Shift Assay; Glutathione; Indicators and Reagents; Monocrotaline; Nucleic Acid Denaturation; Oligonucleotides; Pyrroles; Tyrosine | 2004 |
Identification of a novel epitope in the thyroid-stimulating hormone receptor ectodomain acting as intramolecular signaling interface.
Topics: Amino Acid Motifs; Amino Acid Sequence; Animals; Asparagine; Aspartic Acid; Cell Line; Cell Membrane; Cell Separation; Computational Biology; COS Cells; Cyclic AMP; Cysteine; DNA, Complementary; Dose-Response Relationship, Drug; Epitopes; Flow Cytometry; Humans; Interleukin-8; Microscopy, Confocal; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; Peptides; Protein Binding; Protein Conformation; Protein Structure, Secondary; Protein Structure, Tertiary; Receptors, Thyrotropin; Serine; Signal Transduction; Time Factors; Transfection | 2004 |
Effects of a novel disulfide bond and engineered electrostatic interactions on the thermostability of azurin.
Topics: Arginine; Aspartic Acid; Azurin; Calorimetry, Differential Scanning; Copper; Crystallography, X-Ray; Cysteine; Disulfides; Lysine; Mass Spectrometry; Mutagenesis, Site-Directed; Protein Denaturation; Pseudomonas aeruginosa; Spectrometry, Mass, Electrospray Ionization; Spectrophotometry; Static Electricity; Thermodynamics; Zinc | 2004 |
ECEPE proteins: a novel family of eukaryotic cysteine proteinases.
Topics: Amino Acid Sequence; Aspartic Acid; Catalysis; Cysteine; Cysteine Endopeptidases; Eukaryotic Cells; Glutamine; Guanylate Cyclase; Histidine; Molecular Sequence Data; Papain; Sequence Homology, Amino Acid | 2004 |
On the role of the conserved aspartate in the hydrolysis of the phosphocysteine intermediate of the low molecular weight tyrosine phosphatase.
Topics: Animals; Aspartic Acid; Cattle; Cysteine; Hydrolysis; Kinetics; Models, Molecular; Molecular Weight; Phosphorylation; Protein Tyrosine Phosphatases; Quantum Theory; Thermodynamics | 2004 |
Coupled sodium/glucose cotransport by SGLT1 requires a negative charge at position 454.
Topics: Animals; Aspartic Acid; Cell Membrane; Cysteine; Glucose; Histidine; Humans; Membrane Glycoproteins; Methylglucosides; Monosaccharide Transport Proteins; Mutagenesis, Site-Directed; Oocytes; Patch-Clamp Techniques; Protein Binding; Rhodamines; Sodium; Sodium-Glucose Transporter 1; Spectrometry, Fluorescence; Xenopus laevis | 2004 |
Association between biallelic and monoallelic germline MYH gene mutations and colorectal cancer risk.
Topics: Adenomatous Polyposis Coli; Aspartic Acid; Base Pair Mismatch; Biomarkers, Tumor; Case-Control Studies; Colorectal Neoplasms; Colorectal Neoplasms, Hereditary Nonpolyposis; Cysteine; DNA Glycosylases; DNA Mutational Analysis; DNA, Neoplasm; Gene Frequency; Genetic Predisposition to Disease; Germ-Line Mutation; Glycine; Humans; Loss of Heterozygosity; Ontario; Phenotype; Risk Factors; Tyrosine | 2004 |
Further studies on the fragmentation of protonated ions of peptides containing aspartic acid, glutamic acid, cysteine sulfinic acid, and cysteine sulfonic acid.
Topics: Amino Acid Sequence; Aspartic Acid; Cysteine; Glutamic Acid; Oligopeptides; Peptides; Spectrometry, Mass, Electrospray Ionization; Sulfonic Acids | 2005 |
Substrate-trapping techniques in the identification of cellular PTP targets.
Topics: Alanine; Aspartic Acid; Catalytic Domain; Cysteine; Glutathione; Mutation; Protein Tyrosine Phosphatases; Recombinant Fusion Proteins; Serine; Substrate Specificity; Vanadates | 2005 |
Parasite killing in Plasmodium vivax malaria by nitric oxide: implication of aspartic protease inhibition.
Topics: Animals; Aspartic Acid; Aspartic Acid Endopeptidases; Catalase; Catalytic Domain; Chromatography, High Pressure Liquid; Cysteine; Dithiothreitol; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Erythrocytes; Gelatin; Glutamate Dehydrogenase (NADP+); Glutathione; Hydrogen-Ion Concentration; Inhibitory Concentration 50; Malaria, Vivax; Molsidomine; Nitric Oxide; Nitric Oxide Donors; Nitroprusside; Pepsin A; Pepstatins; Plasmodium; Plasmodium vivax; Protease Inhibitors; Reactive Nitrogen Species; S-Nitrosoglutathione; Time Factors; Up-Regulation | 2004 |
Active site aspartate residues are critical for tryptophan tryptophylquinone biogenesis in methylamine dehydrogenase.
Topics: Aspartic Acid; Binding Sites; Crystallography, X-Ray; Cysteine; Disulfides; Indolequinones; Kinetics; Mass Spectrometry; Methylamines; Models, Chemical; Models, Molecular; Models, Statistical; Mutation; Oxidoreductases Acting on CH-NH Group Donors; Oxygen; Paracoccus denitrificans; Protein Conformation; Tryptophan | 2005 |
Deamidation and disulfide bridge formation in human calbindin D28k with effects on calcium binding.
Topics: Alkylation; Amino Acid Sequence; Asparagine; Aspartic Acid; Calbindin 1; Calbindins; Calcium; Cysteine; Electrophoresis, Agar Gel; Humans; Mass Spectrometry; Molecular Sequence Data; Protein Processing, Post-Translational; S100 Calcium Binding Protein G | 2005 |
T-786C polymorphism of the endothelial nitric oxide synthase gene is associated with albuminuria in the diabetes heart study.
Topics: Aged; Albuminuria; Aspartic Acid; Creatinine; Cysteine; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Exons; Female; Genetic Predisposition to Disease; Genotype; Glutamic Acid; Homozygote; Humans; Linkage Disequilibrium; Male; Middle Aged; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Odds Ratio; Polymorphism, Genetic; Promoter Regions, Genetic; Threonine | 2005 |
Site-directed mutagenesis and molecular modelling studies show the role of Asp82 and cysteines in rat acylase 1, a member of the M20 family.
Topics: Amidohydrolases; Animals; Aspartic Acid; Base Sequence; Cysteine; DNA Primers; Kidney; Models, Molecular; Mutagenesis, Site-Directed; Rats | 2005 |
Point mutations at the type I Cu ligands, Cys457 and Met467, and at the putative proton donor, Asp105, in Myrothecium verrucaria bilirubin oxidase and reactions with dioxygen.
Topics: Alanine; Amino Acid Substitution; Asparagine; Aspartic Acid; Copper; Cysteine; Dithionite; Fungal Proteins; Glutamic Acid; Glutamine; Hypocreales; Ligands; Methionine; Oxidation-Reduction; Oxidoreductases Acting on CH-CH Group Donors; Oxygen; Point Mutation; Protons; Serine | 2005 |
Engineering dihydropteroate synthase (DHPS) for efficient expression on M13 phage.
Topics: Amino Acid Substitution; Asparagine; Aspartic Acid; Bacteriophage M13; Cysteine; Dihydropteroate Synthase; Immunoassay; Mutation; Peptide Library; Periplasm; Periplasmic Proteins; Protein Engineering | 2005 |
Conserved glycine residues in the cytoplasmic domain of the aspartate receptor play essential roles in kinase coupling and on-off switching.
Topics: Adaptation, Physiological; Alanine; Amino Acid Substitution; Aspartic Acid; Bacterial Proteins; Chemotaxis; Conserved Sequence; Cysteine; Cytoplasm; Disulfides; Enzyme Activation; Escherichia coli; Escherichia coli Proteins; Glycine; Histidine Kinase; Membrane Proteins; Methyl-Accepting Chemotaxis Proteins; Mutagenesis, Site-Directed; Protein Structure, Tertiary; Receptors, Amino Acid; Salmonella typhimurium; Signal Transduction | 2005 |
Site-directed disulfide mapping of residues contributing to the Ca2+ and K+ binding pocket of the NCKX2 Na+/Ca2+-K+ exchanger.
Topics: Amino Acid Sequence; Aspartic Acid; Binding Sites; Calcium; Cell Line; Cell Membrane; Cross-Linking Reagents; Cysteine; Disulfides; Glutamic Acid; Humans; Hydrolysis; Hydrophobic and Hydrophilic Interactions; Molecular Sequence Data; Mutagenesis, Insertional; Peptide Mapping; Phenanthrolines; Potassium; Protein Sorting Signals; Protein Structure, Secondary; Repetitive Sequences, Amino Acid; Serine; Sodium-Calcium Exchanger | 2005 |
Functional interactions between the subunits of the lactose transporter from Streptococcus thermophilus.
Topics: Aspartic Acid; Cysteine; Dimerization; Kinetics; Lactose; Membrane Transport Proteins; Mutation; Protein Binding; Protein Structure, Quaternary; Protein Subunits; Streptococcus thermophilus | 2005 |
Characterization of disulfide bonds in human nucleoside triphosphate diphosphohydrolase 3 (NTPDase3): implications for NTPDase structural modeling.
Topics: Amino Acid Sequence; Aspartic Acid; Cysteine; Disulfides; Glycosylation; Humans; Hydrogen-Ion Concentration; Hydrolysis; Models, Molecular; Molecular Sequence Data; Mutation; Phenotype; Proline; Protein Structure, Tertiary; Protein Transport; Pyrophosphatases; Sequence Alignment | 2005 |
A helical hairpin region of soluble annexin B12 refolds and forms a continuous transmembrane helix at mildly acidic pH.
Topics: Annexins; Aspartic Acid; Binding Sites; Calcium; Crystallography, X-Ray; Cysteine; Electron Spin Resonance Spectroscopy; Escherichia coli; Glutamic Acid; Humans; Hydrogen-Ion Concentration; Lipid Bilayers; Models, Molecular; Mutation; Nitric Oxide; Protein Conformation; Protein Folding; Protein Structure, Secondary; Protein Structure, Tertiary; Spin Labels; Thermodynamics | 2005 |
Low molecular weight protein tyrosine phosphatase: catalytic mechanism and physiologic function.
Topics: Amino Acid Sequence; Animals; Arginine; Aspartic Acid; Cysteine; Mice; Molecular Weight; Mutagenesis, Site-Directed; Neoplasm Metastasis; NIH 3T3 Cells; Protein Tyrosine Phosphatases | 2004 |
Fully metallated S134N Cu,Zn-superoxide dismutase displays abnormal mobility and intermolecular contacts in solution.
Topics: Amyotrophic Lateral Sclerosis; Aspartic Acid; Binding Sites; Circular Dichroism; Copper; Crystallization; Crystallography, X-Ray; Cysteine; Disulfides; Dose-Response Relationship, Drug; Electron Spin Resonance Spectroscopy; Humans; Hydrogen Bonding; Ions; Magnetic Resonance Spectroscopy; Models, Molecular; Movement; Mutagenesis; Mutation; Polymerase Chain Reaction; Proteins; Spectrophotometry; Superoxide Dismutase; Zinc | 2005 |
Structure and function of lysosomal phospholipase A2: identification of the catalytic triad and the role of cysteine residues.
Topics: Alanine; Amino Acid Sequence; Animals; Aspartic Acid; Brain; Catalysis; Catalytic Domain; Cattle; Chlorocebus aethiops; Chromatography; COS Cells; Cysteine; Disulfides; Electrophoresis, Polyacrylamide Gel; Histidine; Humans; Immunoblotting; Kidney; Lysosomes; Macrophages; Mice; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; Open Reading Frames; Phosphatidylcholines; Phosphatidylethanolamines; Phospholipases A; Phospholipases A2; Phospholipids; Plasmids; Pulmonary Surfactants; Rats; Sequence Homology, Amino Acid; Serine; Surface-Active Agents; Transfection | 2005 |
Localization of a substrate binding domain of the human reduced folate carrier to transmembrane domain 11 by radioaffinity labeling and cysteine-substituted accessibility methods.
Topics: Amino Acid Sequence; Anions; Aspartic Acid; Blotting, Western; Cell Line; Cell Membrane; Cysteine; Cytosol; Folic Acid; Glutamine; HeLa Cells; Histidine; Humans; K562 Cells; Leucovorin; Membrane Transport Proteins; Mesylates; Microscopy, Fluorescence; Molecular Sequence Data; Mutagenesis; Mutation; Peptides; Protein Binding; Protein Conformation; Protein Structure, Secondary; Protein Structure, Tertiary; Reduced Folate Carrier Protein; Sulfhydryl Reagents; Temperature; Thiocyanates; Time Factors; Transfection; Tyrosine | 2005 |
Conformational changes of pore helix coupled to gating of TRPV5 by protons.
Topics: Amino Acid Sequence; Animals; Aspartic Acid; Calcium Channels; Cysteine; Hydrogen-Ion Concentration; Ion Channel Gating; Lysine; Molecular Sequence Data; Protein Conformation; Protons; Rabbits; Sequence Alignment | 2005 |
Sulfhydryl modification of cysteine mutants of a neuronal glutamate transporter reveals an inverse relationship between sodium dependent conformational changes and the glutamate-gated anion conductance.
Topics: Amino Acid Transport System X-AG; Animals; Aspartic Acid; Cell Line; Cloning, Molecular; Cysteine; Dose-Response Relationship, Drug; Drug Interactions; Electric Stimulation; Glutamates; Humans; Ion Channel Gating; Lithium; Membrane Potentials; Mesylates; Microinjections; Mutagenesis; Mutation; Neurons; Oocytes; Patch-Clamp Techniques; Protein Conformation; Protein Structure, Tertiary; Sodium; Sulfhydryl Compounds; Transfection; Xenopus | 2005 |
Structure of human phytanoyl-CoA 2-hydroxylase identifies molecular mechanisms of Refsum disease.
Topics: Aspartic Acid; Binding Sites; Coenzyme A; Crystallization; Crystallography, X-Ray; Cysteine; Escherichia coli; Ferrous Compounds; Histidine; Humans; Ketoglutaric Acids; Mixed Function Oxygenases; Models, Molecular; Mutation; Peroxisomes; Phytanic Acid; Protein Binding; Protein Structure, Secondary; Recombinant Proteins; Refsum Disease; Structure-Activity Relationship; Transfection | 2005 |
Endothelial NO synthase polymorphisms and postural tachycardia syndrome.
Topics: Adolescent; Adult; Alleles; Aspartic Acid; Case-Control Studies; Cysteine; Female; Genotype; Glutamic Acid; Heart Rate; Homozygote; Humans; Male; Middle Aged; Nitric Oxide Synthase Type III; Norepinephrine; Polymorphism, Genetic; Posture; Severity of Illness Index; Syndrome; Tachycardia; Threonine | 2005 |
Atypical MRI findings in Canavan disease: a patient with a mild course.
Topics: Aspartic Acid; Bacterial Proteins; Canavan Disease; Child, Preschool; Chromosomes, Human, Pair 7; Cysteine; Female; Globus Pallidus; Humans; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Mutation; Serine Endopeptidases; Tyrosine | 2005 |
Lineage-specific variations of congruent evolution among DNA sequences from three genomes, and relaxed selective constraints on rbcL in Cryptomonas (Cryptophyceae).
Topics: Asparagine; Aspartic Acid; Bayes Theorem; Codon; Cryptophyta; Cysteine; DNA; DNA, Ribosomal; Evolution, Molecular; Genome; Histidine; Likelihood Functions; Phenylalanine; Photosynthesis; Phylogeny; Plastids; Polymerase Chain Reaction; Ribulose-Bisphosphate Carboxylase; Sequence Analysis, DNA; Tyrosine | 2005 |
Role of transmembrane segment 10 in efflux mediated by the staphylococcal multidrug transport protein QacA.
Topics: Amino Acid Sequence; Aspartic Acid; Bacterial Proteins; Binding Sites; Biological Transport; Blotting, Western; Cell Membrane; Cysteine; Drug Resistance, Multiple; Escherichia coli; Kinetics; Maleimides; Membrane Transport Proteins; Methionine; Microscopy, Fluorescence; Molecular Sequence Data; Mutagenesis; Mutation; Phenotype; Protein Binding; Protein Conformation; Protein Structure, Secondary; Protein Structure, Tertiary; Protein Transport; Solvents; Staphylococcus aureus | 2006 |
A novel conotoxin from Conus striatus, mu-SIIIA, selectively blocking rat tetrodotoxin-resistant sodium channels.
Topics: Amino Acid Sequence; Animals; Aspartic Acid; Base Sequence; Conotoxins; Conus Snail; Cysteine; Dose-Response Relationship, Drug; Glutamine; Hydroxyproline; Molecular Sequence Data; Nervous System; Peptide Fragments; Rats; Serine; Sodium Channel Blockers; Sodium Channels; Structure-Activity Relationship; Tetrodotoxin | 2006 |
Linker chains of the gigantic hemoglobin of the earthworm Lumbricus terrestris: primary structures of linkers L2, L3, and L4 and analysis of the connectivity of the disulfide bonds in linker L1.
Topics: Amino Acid Sequence; Animals; Aspartic Acid; Base Sequence; Binding Sites; Calcium; Chromatography, High Pressure Liquid; Cysteine; Disulfides; Dithiothreitol; DNA, Complementary; Glutamic Acid; Heme; Hemoglobins; Histidine; Humans; Ligands; Mass Spectrometry; Models, Molecular; Molecular Sequence Data; Oligochaeta; Protein Binding; Protein Processing, Post-Translational; Protein Structure, Tertiary; Receptors, LDL; RNA, Messenger; Sequence Homology, Amino Acid; Sodium Dodecyl Sulfate; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Superoxide Dismutase | 2006 |
Mechanistic pathways of formation of acrylamide from different amino acids.
Topics: Acrylamide; Acrylamides; Acrylates; Amino Acids; Ammonia; Asparagine; Aspartic Acid; beta-Alanine; Carbohydrates; Carnosine; Creatine; Cysteine; Fructose; Gas Chromatography-Mass Spectrometry; Hydrolysis; Mass Spectrometry; Models, Chemical; Pyruvic Acid; Serine; Time Factors | 2005 |
Fragmentation of the deprotonated ions of peptides containing cysteine, cysteine sulfinic acid, cysteine sulfonic acid, aspartic acid, and glutamic acid.
Topics: Amino Acid Sequence; Aspartic Acid; Cysteine; Glutamic Acid; Molecular Sequence Data; Peptides; Spectrometry, Mass, Electrospray Ionization; Sulfonic Acids | 2006 |
Native chemical ligation in covalent caspase inhibition by p35.
Topics: Aspartic Acid; Caspase Inhibitors; Caspases; Cysteine; Electrons; Electrophoresis, Polyacrylamide Gel; Models, Molecular; Substrate Specificity; Viral Proteins | 2006 |
Roles of adjoining Asp and Cys residues of first matrix-facing loop in transport activity of yeast and bovine mitochondrial ADP/ATP carriers.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Amino Acid Sequence; Animals; Aspartic Acid; Cattle; Cysteine; Mitochondrial Membranes; Molecular Sequence Data; Nucleotide Transport Proteins; Protein Structure, Tertiary; Saccharomyces cerevisiae Proteins | 2006 |
The effect of the metabolic syndrome, hepatic steatosis and steatohepatitis on liver fibrosis in hereditary hemochromatosis.
Topics: Adult; Aged; Aspartic Acid; Cysteine; Fatty Liver; Female; Genetic Predisposition to Disease; Glucose Intolerance; Hemochromatosis; Hepatitis; Heterozygote; Histidine; Homozygote; Humans; Iron Overload; Liver Cirrhosis; Male; Metabolic Syndrome; Middle Aged; Multivariate Analysis; Predictive Value of Tests; Prospective Studies; Risk Factors; Tyrosine | 2006 |
Mutagenic definition of a papain-like catalytic triad, sufficiency of the N-terminal domain for single-site core catalytic enzyme acylation, and C-terminal domain for augmentative metal activation of a eukaryotic phytochelatin synthase.
Topics: Acylation; Amino Acid Sequence; Aminoacyltransferases; Arabidopsis; Aspartic Acid; Binding Sites; Cadmium; Catalysis; Cysteine; Enzyme Activation; Histidine; Molecular Sequence Data; Mutagenesis, Site-Directed; Papain; Protein Structure, Tertiary; Sequence Homology, Amino Acid | 2006 |
Deducing the transmembrane domain organization of presenilin-1 in gamma-secretase by cysteine disulfide cross-linking.
Topics: Amino Acid Sequence; Amyloid Precursor Protein Secretases; Animals; Aspartic Acid; Aspartic Acid Endopeptidases; Binding Sites; Blastocyst; Cells, Cultured; Conserved Sequence; Cross-Linking Reagents; Cysteine; Disulfides; Endopeptidases; Enzyme Inhibitors; Female; HeLa Cells; Humans; Membrane Proteins; Mice; Mice, Knockout; Microsomes; Models, Molecular; Molecular Sequence Data; Mutation, Missense; Oxidation-Reduction; Pregnancy; Presenilin-1; Protein Binding; Protein Conformation; Protein Structure, Tertiary; Sequence Homology, Amino Acid; Stem Cells | 2006 |
Binding and transport of metal ions at the dimer interface of the Escherichia coli metal transporter YiiP.
Topics: Aspartic Acid; Biological Transport; Cadmium; Cations, Divalent; Conserved Sequence; Copper; Cross-Linking Reagents; Cysteine; Dimerization; Disulfides; Escherichia coli Proteins; Membrane Transport Proteins; Mercury; Mutagenesis, Site-Directed; Protein Binding; Zinc | 2006 |
DNA-repair gene polymorphisms predict favorable clinical outcome among patients with advanced squamous cell carcinoma of the head and neck treated with cisplatin-based induction chemotherapy.
Topics: Adult; Aged; Aged, 80 and over; Alanine; Antineoplastic Combined Chemotherapy Protocols; Arginine; Asparagine; Aspartic Acid; Carcinoma, Squamous Cell; Cisplatin; Cysteine; DNA Repair; DNA-Binding Proteins; DNA, Neoplasm; Endonucleases; Female; Gene Frequency; Genotype; Glutamine; Head and Neck Neoplasms; Humans; Lysine; Male; Middle Aged; Multivariate Analysis; Neoplasm Staging; Polymerase Chain Reaction; Polymorphism, Restriction Fragment Length; Polymorphism, Single Nucleotide; Predictive Value of Tests; Prognosis; Proportional Hazards Models; Prospective Studies; Survival Analysis; Treatment Outcome; X-ray Repair Cross Complementing Protein 1; Xeroderma Pigmentosum Group D Protein | 2006 |
[Analysis of amino acid contents between wild plant QiBaiZhu and YunnanBaiZhu].
Topics: Amino Acids; Amino Acids, Essential; Arginine; Aspartic Acid; Atractylodes; Cysteine; Molecular Structure; Plant Roots; Plants, Medicinal | 2006 |
Biosynthesis of phosphoserine in the Methanococcales.
Topics: Archaeal Proteins; Aspartic Acid; Chromatography, Affinity; Cysteine; Electrophoresis, Polyacrylamide Gel; Escherichia coli; Genetic Complementation Test; Methanococcales; Mutation; Phosphoglycerate Dehydrogenase; Phosphoserine; Phylogeny; Pyruvates; Serine; Transaminases | 2007 |
Structure of the catalytic pore of gamma-secretase probed by the accessibility of substituted cysteines.
Topics: Amino Acid Motifs; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Amyloid Precursor Protein Secretases; Animals; Aspartic Acid; Brain; Brain Chemistry; Catalytic Domain; Cell Line; Cell Membrane; Cysteine; Humans; Membrane Lipids; Mice; Models, Molecular; Mutagenesis, Site-Directed; Neurochemistry; Presenilin-1; Protein Structure, Tertiary; Proteomics | 2006 |
Mutagenesis and modeling of the peroxiredoxin (Prx) complex with the NMR structure of ATP-bound human sulfiredoxin implicate aspartate 187 of Prx I as the catalytic residue in ATP hydrolysis.
Topics: Adenosine Triphosphate; Asparagine; Aspartic Acid; Catalysis; Crystallography, X-Ray; Cysteine; Humans; Hydrolysis; Magnetic Resonance Spectroscopy; Models, Chemical; Models, Molecular; Mutagenesis, Site-Directed; Oxidation-Reduction; Oxidoreductases; Oxidoreductases Acting on Sulfur Group Donors; Peroxiredoxins; Protein Structure, Tertiary | 2006 |
Aqueous access pathways in ATP synthase subunit a. Reactivity of cysteine substituted into transmembrane helices 1, 3, and 5.
Topics: Aspartic Acid; Cell Membrane; Cysteine; Cytoplasm; Escherichia coli; Ethylmaleimide; Mutation; Protein Conformation; Protein Structure, Secondary; Protein Structure, Tertiary; Proton-Translocating ATPases; Protons; Silver; Water | 2007 |
The carboxylate shift in zinc enzymes: a computational study.
Topics: Aspartic Acid; Carboxylic Acids; Catalytic Domain; Computational Biology; Crystallography, X-Ray; Cysteine; Electron Transport; Enzymes; Glutamic Acid; Histidine; Ligands; Metalloproteins; Oxygen; Protein Conformation; Zinc | 2007 |
PTEN catalysis of phospholipid dephosphorylation reaction follows a two-step mechanism in which the conserved aspartate-92 does not function as the general acid--mechanistic analysis of a familial Cowden disease-associated PTEN mutation.
Topics: Animals; Aspartic Acid; Binding Sites; Catalysis; Conserved Sequence; Cysteine; Glycine; Hamartoma Syndrome, Multiple; Humans; Hydrogen-Ion Concentration; Hydrolysis; Kinetics; Models, Biological; Mutation; Phosphatidylethanolamines; Phosphatidylinositol Phosphates; Phospholipids; Phosphoprotein Phosphatases; Phosphorus Radioisotopes; Phosphorylation; PTEN Phosphohydrolase; Rats; Time Factors | 2007 |
Loop dynamics and ligand binding kinetics in the reaction catalyzed by the Yersinia protein tyrosine phosphatase.
Topics: Amino Acid Sequence; Aspartic Acid; Binding Sites; Binding, Competitive; Catalysis; Catalytic Domain; Catechols; Crystallization; Cysteine; Hot Temperature; Kinetics; Lasers; Ligands; Models, Molecular; Molecular Structure; Protein Binding; Protein Conformation; Protein Structure, Secondary; Protein Structure, Tertiary; Protein Tyrosine Phosphatases; Spectrometry, Fluorescence; Substrate Specificity; Thermodynamics; Tryptophan; Yersinia | 2007 |
Aspartate-444 is essential for productive substrate interactions in a neuronal glutamate transporter.
Topics: Alanine; Animals; Aspartic Acid; Binding Sites; Cysteine; Dicarboxylic Acid Transporters; Excitatory Amino Acid Transporter 3; Glutamic Acid; HeLa Cells; Humans; Microinjections; Mutation; Neurons; Oocytes; Protein Conformation; Protein Structure, Tertiary; Rabbits; Serine; Succinic Acid; Transfection; Xenopus laevis | 2007 |
Active-site properties of the oxidized and reduced C-terminal domain of DsbD obtained by NMR spectroscopy.
Topics: Amino Acid Motifs; Aspartic Acid; Binding Sites; Cysteine; Escherichia coli; Escherichia coli Proteins; Glutamic Acid; Hydrogen-Ion Concentration; Models, Molecular; Mutation; Nuclear Magnetic Resonance, Biomolecular; Oxidation-Reduction; Oxidoreductases; Protein Structure, Tertiary | 2007 |
L-Cysteine and glutathione restore the reduction of rat hippocampal Na+, K+-ATPase activity induced by aspartame metabolites.
Topics: Animals; Animals, Suckling; Aspartame; Aspartic Acid; Cysteine; Dose-Response Relationship, Drug; Female; Glutathione; Hippocampus; In Vitro Techniques; Male; Methanol; Phenylalanine; Rats; Rats, Wistar; Sodium-Potassium-Exchanging ATPase; Sweetening Agents | 2007 |
Interaction between lysine 102 and aspartate 338 in the insect amino acid cotransporter KAAT1.
Topics: Amino Acid Sequence; Amino Acid Substitution; Amino Acid Transport Systems, Neutral; Animals; Aspartic Acid; Binding Sites; Biological Transport; Cross-Linking Reagents; Cysteine; Dithiothreitol; Female; Insect Proteins; Kinetics; Lepidoptera; Lysine; Models, Molecular; Molecular Sequence Data; Oocytes; Phenanthrolines; Potassium; Protein Structure, Tertiary; Sequence Homology, Amino Acid; Sodium; Tryptophan; Xenopus laevis | 2007 |
Constitutive excitation by Gly90Asp rhodopsin rescues rods from degeneration caused by elevated production of cGMP in the dark.
Topics: Adaptation, Ocular; Animals; Aspartic Acid; Calcium; Cyclic GMP; Cysteine; Dark Adaptation; Disease Models, Animal; Electroretinography; Gene Expression Regulation; Glycine; Guanylate Cyclase-Activating Proteins; Mice; Mice, Transgenic; Microscopy, Electron, Transmission; Physical Stimulation; Retina; Retinal Degeneration; Retinal Rod Photoreceptor Cells; Rhodopsin; Tyrosine | 2007 |
Accurate computation of reduction potentials of 4Fe-4S clusters indicates a carboxylate shift in Pyrococcus furiosus ferredoxin.
Topics: Aspartic Acid; Carboxylic Acids; Chemistry; Crystallography, X-Ray; Cysteine; Ferredoxins; Iron-Sulfur Proteins; Ligands; Models, Theoretical; Molecular Conformation; Oxidation-Reduction; Pyrococcus furiosus; Reproducibility of Results; Software; Temperature | 2007 |
Distinct structural and functional roles of conserved residues in the first extracellular domain of receptors for corticotropin-releasing factor and related G-protein-coupled receptors.
Topics: Animals; Arginine; Aspartic Acid; Chlorocebus aethiops; Corticotropin-Releasing Hormone; COS Cells; Cysteine; Immunohistochemistry; Ligands; Magnetic Resonance Spectroscopy; Molecular Conformation; Mutagenesis; Mutation; Peptide Fragments; Protein Binding; Protein Structure, Tertiary; Receptors, G-Protein-Coupled; Salts | 2007 |
Structural elements of the cholesterol-dependent cytolysins that are responsible for their cholesterol-sensitive membrane interactions.
Topics: Amino Acid Substitution; Aspartic Acid; Bacterial Proteins; Bacterial Toxins; Bacteriocins; Cholesterol; Crystallography, X-Ray; Cysteine; Cytotoxins; Glycine; Hemolysin Proteins; Liposomes; Membranes, Artificial; Porosity; Protein Conformation; Tryptophan | 2007 |
Oxidative stress on EAAC1 is involved in MPTP-induced glutathione depletion and motor dysfunction.
Topics: 1-Methyl-4-phenylpyridinium; Acetylcysteine; Animals; Aspartic Acid; Behavior, Animal; Cysteine; Disease Models, Animal; Drug Interactions; Excitatory Amino Acid Transporter 1; Free Radical Scavengers; Glutathione; Humans; Hydrogen Peroxide; Hydroxamic Acids; In Vitro Techniques; Indazoles; Male; Mice; Mice, Inbred C57BL; Movement Disorders; MPTP Poisoning; Neuroprotective Agents; Oxidative Stress; Substantia Nigra | 2008 |
A combined approach of mass spectrometry, molecular modeling, and site-directed mutagenesis highlights key structural features responsible for the thermostability of Sulfolobus solfataricus carboxypeptidase.
Topics: Alkylation; Amino Acid Sequence; Amino Acid Substitution; Asparagine; Aspartic Acid; Carboxypeptidases; Cysteine; Disulfides; Enzyme Activation; Enzyme Stability; Hot Temperature; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kinetics; Mass Spectrometry; Models, Chemical; Models, Molecular; Molecular Sequence Data; Molecular Weight; Mutagenesis, Site-Directed; Oxidation-Reduction; Pepsin A; Protein Engineering; Protein Structure, Secondary; Protein Subunits; Serine; Sulfolobus solfataricus; Thermodynamics; Trypsin | 2008 |
Generation of nucleophilic character in the Cys25/His159 ion pair of papain involves Trp177 but not Asp158.
Topics: Aspartic Acid; Cysteine; Histidine; Models, Molecular; Nuclear Magnetic Resonance, Biomolecular; Papain; Spectrometry, Mass, Electrospray Ionization; Static Electricity; Tryptophan | 2008 |
Autoproteolytic cleavage and activation of human acid ceramidase.
Topics: Animals; Arginine; Aspartic Acid; CHO Cells; Cricetinae; Cricetulus; Cysteine; Enzyme Activation; Galactosylgalactosylglucosylceramidase; Humans; Hydrogen Bonding; Isoleucine; Mutagenesis, Site-Directed; Protein Conformation; Recombinant Proteins | 2008 |
HFE gene mutations in a population of Italian Parkinson's disease patients.
Topics: Adult; Aged; Aged, 80 and over; Aspartic Acid; Cysteine; DNA Mutational Analysis; Female; Gene Frequency; Genotype; Hemochromatosis Protein; Histidine; Histocompatibility Antigens Class I; Humans; Italy; Male; Membrane Proteins; Middle Aged; Mutation; Parkinson Disease; Serine | 2008 |
l-Cysteine and glutathione restore the modulation of rat frontal cortex Na+, K+ -ATPase activity induced by aspartame metabolites.
Topics: Animals; Animals, Suckling; Antioxidants; Aspartame; Aspartic Acid; Biotransformation; Ca(2+) Mg(2+)-ATPase; Cysteine; Female; Glutathione; Male; Phenylalanine; Prefrontal Cortex; Rats; Rats, Wistar; Sodium-Potassium-Exchanging ATPase; Sweetening Agents | 2008 |
A novel phosphorylated glycoprotein in the shell matrix of the oyster Crassostrea nippona.
Topics: Amino Acid Sequence; Animals; Aspartic Acid; Base Sequence; Calcium; Crassostrea; Cysteine; Disulfides; DNA, Complementary; Glycoproteins; Molecular Sequence Data; Phosphoproteins; Phosphorylation; Protein Structure, Tertiary; Sequence Homology, Amino Acid; Time Factors | 2008 |
Molecular analysis of the parkin gene in South African patients diagnosed with Parkinson's disease.
Topics: Adolescent; Adult; Aged; Arginine; Asparagine; Aspartic Acid; Cysteine; DNA Mutational Analysis; Exons; Female; Gene Frequency; Heterozygote; Humans; Male; Middle Aged; Parkinson Disease; Point Mutation; Sequence Deletion; South Africa; Ubiquitin-Protein Ligases; Young Adult | 2009 |
A second conserved GAF domain cysteine is required for the blue/green photoreversibility of cyanobacteriochrome Tlr0924 from Thermosynechococcus elongatus.
Topics: Aspartic Acid; Bacterial Proteins; Circular Dichroism; Color; Conserved Sequence; Cyanobacteria; Cysteine; Light; Mutant Proteins; Phytochrome; Protein Structure, Tertiary; Pyrroles; Structure-Activity Relationship; Sulfides; Temperature | 2008 |
The C-terminal PAL motif and transmembrane domain 9 of presenilin 1 are involved in the formation of the catalytic pore of the gamma-secretase.
Topics: Amyloid Precursor Protein Secretases; Animals; Aspartic Acid; Cell Line, Transformed; Cysteine; Humans; Mice; Models, Molecular; Mutation; Presenilin-1; Protein Interaction Domains and Motifs; Protein Structure, Tertiary | 2008 |
Asp330 and Tyr331 in the C-terminal cysteine-rich region of the luteinizing hormone receptor are key residues in hormone-induced receptor activation.
Topics: Amino Acid Sequence; Aspartic Acid; Cell Line; Cysteine; Disulfides; Genes, Reporter; Humans; Models, Biological; Molecular Sequence Data; Mutation; Protein Conformation; Protein Structure, Tertiary; Receptors, FSH; Receptors, LH; Tyrosine | 2008 |
A conserved Cys-loop receptor aspartate residue in the M3-M4 cytoplasmic loop is required for GABAA receptor assembly.
Topics: Amino Acid Motifs; Amino Acid Sequence; Aspartic Acid; Cysteine; Cytoplasm; Endoplasmic Reticulum; Glycoside Hydrolases; Humans; Models, Biological; Molecular Sequence Data; Mutation; Patch-Clamp Techniques; Receptors, GABA-A; Sequence Homology, Amino Acid; Synaptic Transmission | 2008 |
Identification of four novel types of in vitro protein modifications.
Topics: Algorithms; Amino Acid Sequence; Animals; Aspartic Acid; Cattle; Chromatography, High Pressure Liquid; Cysteine; Glutamic Acid; Glycerol; Lysine; Mass Spectrometry; Molecular Sequence Data; Molecular Structure; Protein Processing, Post-Translational; Proteins; Reproducibility of Results; Sequence Alignment; Serum Albumin, Bovine | 2008 |
Synthesis of pdCpAs and transfer RNAs activated with derivatives of aspartic acid and cysteine.
Topics: Aspartic Acid; Cysteine; Dinucleoside Phosphates; RNA, Transfer; Structure-Activity Relationship; Transfer RNA Aminoacylation | 2008 |
Why do cysteine dioxygenase enzymes contain a 3-His ligand motif rather than a 2His/1Asp motif like most nonheme dioxygenases?
Topics: Amino Acid Motifs; Aspartic Acid; Biocatalysis; Catalytic Domain; Cysteine; Cysteine Dioxygenase; Heme; Histidine; Humans; Ligands; Models, Chemical; Models, Molecular | 2009 |
Transmembrane domain 8 of the {gamma}-aminobutyric acid transporter GAT-1 lines a cytoplasmic accessibility pathway into its binding pocket.
Topics: Aspartic Acid; Cysteine; Cytoplasm; GABA Plasma Membrane Transport Proteins; gamma-Aminobutyric Acid; HeLa Cells; Humans; Models, Biological; Mutation; Protein Binding; Protein Structure, Secondary; Protein Structure, Tertiary; Protein Transport; Serine | 2009 |
Gas-phase IR spectroscopy of deprotonated amino acids.
Topics: Amino Acids; Anions; Aspartic Acid; Cysteine; Gases; Glutamic Acid; Phenylalanine; Protons; Serine; Spectrophotometry; Spectrophotometry, Infrared; Tyrosine | 2009 |
Molecular recognition of the palmitoylation substrate Vac8 by its palmitoyltransferase Pfa3.
Topics: Acetyltransferases; Acyltransferases; Amino Acid Sequence; Aspartic Acid; Cysteine; Histidine; Lipoylation; Molecular Sequence Data; Mutagenesis, Site-Directed; Recombinant Fusion Proteins; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Sequence Homology, Amino Acid; src Homology Domains; Vacuoles; Vesicular Transport Proteins | 2009 |
Smart surface of water-induced superhydrophobicity.
Topics: Acrylamides; Acrylic Resins; Aspartic Acid; Cysteine; Hydrophobic and Hydrophilic Interactions; Membranes, Artificial; Polymers; Surface Properties; Water; Wettability | 2009 |
Zinc binding in pestivirus N(pro) is required for interferon regulatory factor 3 interaction and degradation.
Topics: Amino Acid Sequence; Animals; Aspartic Acid; Binding Sites; Cell Line; Classical Swine Fever Virus; Cysteine; Diarrhea Viruses, Bovine Viral; Genes, Reporter; Interferon Regulatory Factor-3; Metalloproteins; Molecular Sequence Data; Mutation; Nucleocapsid Proteins; Protein Stability; Protein Structure, Tertiary; Zinc | 2009 |
Structural adaptability of zinc binding sites: different structures in partially, fully, and heavy-metal loaded states.
Topics: Amino Acid Sequence; Aspartic Acid; Binding Sites; Cysteine; Glutamic Acid; Histidine; Metalloproteins; Molecular Sequence Data; Molecular Structure; Zinc; Zinc Fingers | 2009 |
Monitoring of cleavage preference for caspase-3 using recombinant protein substrates.
Topics: Aspartic Acid; Caspase 3; Conserved Sequence; Cysteine; DNA Primers; Enzyme Activation; Gene Amplification; Green Fluorescent Proteins; Immunoblotting; Oligopeptides; Recombinant Proteins; Substrate Specificity | 2009 |
Transmembrane segment II of NhaA Na+/H+ antiporter lines the cation passage, and Asp65 is critical for pH activation of the antiporter.
Topics: Aspartic Acid; Cations; Cell Membrane; Computer Simulation; Conserved Sequence; Crystallography, X-Ray; Cysteine; Escherichia coli; Escherichia coli Proteins; Gene Expression Regulation, Bacterial; Hydrogen-Ion Concentration; Ion Transport; Lithium; Mesylates; Models, Molecular; Mutation; Periplasm; Phenotype; Protein Conformation; Sodium-Hydrogen Exchangers | 2010 |
Replacement of C305 in heart/muscle-type isozyme of human carnitine palmitoyltransferase I with aspartic acid and other amino acids.
Topics: Amino Acid Sequence; Amino Acid Substitution; Amino Acids; Animals; Aspartic Acid; Carnitine O-Palmitoyltransferase; Chlorocebus aethiops; COS Cells; Cysteine; Gene Expression Regulation, Enzymologic; Humans; Isoenzymes; Muscle, Skeletal; Mutagenesis, Site-Directed; Myocardium; Organ Specificity | 2010 |
X-ray absorption studies of Zn(2+)-binding sites in Escherichia coli transhydrogenase and its betaH91K mutant.
Topics: Amino Acid Substitution; Aspartic Acid; Binding Sites; Cysteine; Escherichia coli Proteins; Glutamic Acid; Histidine; Models, Molecular; Mutation; NADP Transhydrogenases; Protein Binding; Protein Structure, Tertiary; Spectrometry, X-Ray Emission; Zinc | 2010 |
Modulating the pH-activity profile of cellulase by substitution: replacing the general base catalyst aspartate with cysteinesulfinate in cellulase A from Cellulomonas fimi.
Topics: Amino Acid Substitution; Aspartic Acid; Bacterial Proteins; Catalysis; Cellulomonas; Cysteine; Enzyme Activation; Glycoside Hydrolases; Hydrogen-Ion Concentration; Mutagenesis, Site-Directed | 2010 |
The ionization state of D37 in E. coli porin OmpF and the nature of conductance fluctuations in D37 mutants.
Topics: Amino Acid Substitution; Arginine; Aspartic Acid; Cations; Cysteine; Electric Conductivity; Electrophysiology; Escherichia coli; Ethyl Methanesulfonate; Hydrogen-Ion Concentration; Ion Channel Gating; Mutation; Porins; Protein Conformation; Time Factors | 2010 |
Enantiospecific adsorption of amino acids on hydroxylated quartz (10 1 0).
Topics: Adsorption; Amino Acids; Asparagine; Aspartic Acid; Cysteine; Quartz; Serine; Stereoisomerism; Thermodynamics | 2010 |
Biological hydrogen production by the algal biomass Chlorella vulgaris MSU 01 strain isolated from pond sediment.
Topics: Alanine; Anaerobiosis; Aspartic Acid; Biomass; Bioreactors; Carbon; Chlorella vulgaris; Citric Acid; Culture Media; Cysteine; Fermentation; Geologic Sediments; Glucose; Hydrogen; Hydrogen-Ion Concentration; Mannitol; Pyruvic Acid; Succinic Acid | 2011 |
Prevalence of H63D, S65C, and C282Y hereditary hemochromatosis gene variants in Madeira Island (Portugal).
Topics: Adolescent; Adult; Amino Acid Substitution; Aspartic Acid; Cysteine; Gene Frequency; Genotype; Hemochromatosis; Hemochromatosis Protein; Histidine; Histocompatibility Antigens Class I; Humans; Male; Membrane Proteins; Polymorphism, Single Nucleotide; Portugal; Prevalence; Serine; Tyrosine; Young Adult | 2011 |
Radical formation of amino acid precursors in interstellar regions? Ser, Cys and Asp.
Topics: Aspartic Acid; Cysteine; Nitriles; Serine; Thermodynamics | 2010 |
EPR study of 1Asp-3Cys ligated 4Fe-4S iron-sulfur cluster in NB-protein (BchN-BchB) of a dark-operative protochlorophyllide reductase complex.
Topics: Adenosine Triphosphate; Amino Acid Substitution; Aspartic Acid; Bacterial Proteins; Chlorophyll; Cysteine; Electron Spin Resonance Spectroscopy; Iron-Sulfur Proteins; Multigene Family; Nitrogenase; Oxidation-Reduction; Oxidoreductases Acting on CH-CH Group Donors; Rhodobacter capsulatus; Temperature | 2011 |
Expression and biochemical characterization of the human enzyme N-terminal asparagine amidohydrolase.
Topics: Amidohydrolases; Animals; Asparagine; Aspartic Acid; Biocatalysis; Circular Dichroism; Cysteine; Electrophoresis, Polyacrylamide Gel; Humans; Hydrogen-Ion Concentration; Kinetics; Metals; Mice; Models, Chemical; Molecular Structure; Mutation; Recombinant Proteins; Spectrometry, Mass, Electrospray Ionization; Substrate Specificity | 2011 |
Three novel CYP17A1 gene mutations (A82D, R125X, and C442R) found in combined 17α-hydroxylase/17,20-lyase deficiency.
Topics: Adrenal Hyperplasia, Congenital; Adult; Alanine; Amino Acid Substitution; Arginine; Aspartic Acid; Base Sequence; Cells, Cultured; Cysteine; Female; Humans; Mutation, Missense; Steroid 17-alpha-Hydroxylase; Young Adult | 2011 |
Precursors and inhibitors of hydrogen sulfide synthesis affect acute hypoxic pulmonary vasoconstriction in the intact lung.
Topics: Alkynes; Animals; Aspartic Acid; Blood Pressure; Cystathionine beta-Synthase; Cystathionine gamma-Lyase; Cysteine; Glutathione; Glutathione Disulfide; Glycine; Hydrogen Sulfide; Hypoxia; Ketoglutaric Acids; Lung; Male; Maleates; Pulmonary Artery; Rats; Rats, Sprague-Dawley; Sulfurtransferases; Vasoconstriction | 2012 |
Benzimidazole conjugate of 1,1'-thiobis(2-naphthol) as switch-on fluorescence receptor for Ag+ and the complex as secondary recognition ensemble toward Cys, Asp, and Glu in aqueous methanolic solution: synthesis, characterization, ion and amino acid recog
Topics: Amino Acids; Aspartic Acid; Benzimidazoles; Cysteine; Fluorescent Dyes; Glutamic Acid; Ions; Magnetic Resonance Spectroscopy; Methanol; Silver; Solutions; Spectrophotometry, Ultraviolet; Water | 2012 |
Effect of KRAS oncogene substitutions on protein behavior: implications for signaling and clinical outcome.
Topics: Aspartic Acid; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Clinical Trials, Phase II as Topic; Cysteine; Disease-Free Survival; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Genes, ras; Genetic Vectors; Glycine; Humans; Immunoblotting; Immunoprecipitation; Kaplan-Meier Estimate; Lentivirus; Lung Neoplasms; Microarray Analysis; Molecular Targeted Therapy; Mutation; Proto-Oncogene Proteins c-akt; Randomized Controlled Trials as Topic; Signal Transduction; TOR Serine-Threonine Kinases; Treatment Outcome; Valine | 2012 |
The Shigella flexneri effector OspI deamidates UBC13 to dampen the inflammatory response.
Topics: Adaptor Proteins, Signal Transducing; Amidohydrolases; Amino Acid Sequence; Animals; Aspartic Acid; B-Cell CLL-Lymphoma 10 Protein; Biocatalysis; Caspases; Catalytic Domain; Crystallography, X-Ray; Cysteine; Diglycerides; DNA Mutational Analysis; Dysentery, Bacillary; Glutamic Acid; Glutamine; HEK293 Cells; HeLa Cells; Histidine; Humans; Immunity, Innate; Inflammation; Mice; Models, Molecular; Molecular Sequence Data; Mucosa-Associated Lymphoid Tissue Lymphoma Translocation 1 Protein; Neoplasm Proteins; NF-kappa B; Shigella flexneri; TNF Receptor-Associated Factor 6; Ubiquitin-Conjugating Enzymes; Virulence Factors | 2012 |
Spin delocalization over type zero copper.
Topics: Aspartic Acid; Azurin; Copper; Cysteine; Electron Spin Resonance Spectroscopy; Electron Transport; Electrons; Escherichia coli; Histidine; Leucine; Ligands; Magnetic Resonance Spectroscopy; Methionine; Models, Molecular; Mutation; Oxidation-Reduction; Pseudomonas aeruginosa; Recombinant Proteins | 2012 |
Effects of three low-molecular-weight organic acids (LMWOAs) and pH on the mobilization of arsenic and heavy metals (Cu, Pb, and Zn) from mine tailings.
Topics: Arsenic; Aspartic Acid; Copper; Cysteine; Environmental Monitoring; Environmental Restoration and Remediation; Hydrogen-Ion Concentration; Lead; Metals, Heavy; Mining; Molecular Weight; New Brunswick; Succinic Acid; Zinc | 2013 |
Cysteine sulfinic acid decarboxylase activity of Aedes aegypti aspartate 1-decarboxylase: the structural basis of its substrate selectivity.
Topics: Aedes; Animals; Aspartic Acid; Cysteine; Glutamate Decarboxylase; Humans; Insect Proteins; Mutagenesis, Site-Directed; Protein Conformation; Sequence Homology, Amino Acid; Spectrophotometry, Ultraviolet; Substrate Specificity | 2012 |
The role of amino acid residues in the active site of L-methionine γ-lyase from Pseudomonas putida.
Topics: Amino Acid Substitution; Aspartic Acid; Bacterial Proteins; Carbon-Sulfur Lyases; Catalytic Domain; Cysteine; Dimerization; Histidine; Hydrogen Bonding; Kinetics; Lysine; Methionine; Models, Molecular; Protein Structure, Secondary; Protein Subunits; Pseudomonas putida; Recombinant Proteins; Substrate Specificity | 2012 |
Structural features of isomerizable aspartyl residues in human α-crystallins.
Topics: Aging; alpha-Crystallin A Chain; alpha-Crystallin B Chain; Amino Acid Sequence; Aspartic Acid; Cloning, Molecular; Cysteine; Escherichia coli; Humans; Isomerism; Lens, Crystalline; Metalloendopeptidases; Molecular Sequence Data; Proteolysis; Recombinant Proteins; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization | 2012 |
Multiple sensor array of Mn2+, Fe2+, Co2+, Ni2+, Cu2+, and Zn2+ complexes of a triazole linked imino-phenol based calix[4]arene conjugate for the selective recognition of Asp, Glu, Cys, and His.
Topics: Aspartic Acid; Calixarenes; Cysteine; Glutamic Acid; Histidine; Imines; Models, Molecular; Molecular Structure; Organometallic Compounds; Phenols; Spectrometry, Fluorescence; Spectrometry, Mass, Electrospray Ionization; Transition Elements; Triazoles | 2012 |
Aspartic acid-promoted highly selective and sensitive colorimetric sensing of cysteine in rat brain.
Topics: Animals; Aspartic Acid; Brain; Colorimetry; Cysteine; Male; Rats; Rats, Sprague-Dawley | 2012 |
Site saturation mutagenesis demonstrates a central role for cysteine 298 as proton donor to the catalytic site in CaHydA [FeFe]-hydrogenase.
Topics: Aspartic Acid; Catalytic Domain; Clostridium acetobutylicum; Codon; Cysteine; DNA; Escherichia coli; Gene Library; Hydrogen; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrogenase; Iron-Sulfur Proteins; Kinetics; Mutagenesis; Oxidation-Reduction; Oxygen; Plasmids; Protein Structure, Tertiary; Protons | 2012 |
Negative ion fragmentations of disulfide-containing cross-linking reagents are competitive with aspartic acid side-chain-induced cleavages.
Topics: Acetates; Anions; Aspartic Acid; Cross-Linking Reagents; Cysteine; Disulfides; Peptides; Succinimides; Tandem Mass Spectrometry; Thermodynamics | 2013 |
Human organic anion transporter OAT1 is not responsible for glutathione transport but mediates transport of glutamate derivatives.
Topics: Aminohippuric Acids; Aspartic Acid; Biological Transport; Cysteine; Dipeptides; Estrone; Glutamates; Glutathione; Glycine; HEK293 Cells; Humans; Kidney; Organic Anion Transport Protein 1; Organic Anion Transporters, Sodium-Independent; Probenecid; Transfection; Uricosuric Agents | 2013 |
Amino acids form strongly bound anions when substituted with superhalogen ligands.
Topics: Anions; Aspartic Acid; Cysteine; Electrons; Halogens; Ligands; Lysine; Models, Molecular | 2013 |
Replacement of the catalytic nucleophile aspartyl residue of dextran glucosidase by cysteine sulfinate enhances transglycosylation activity.
Topics: Amino Acid Substitution; Aspartic Acid; Bacterial Proteins; Catalysis; Cysteine; Glucosidases; Glycosylation; Mutation, Missense; Streptococcus mutans | 2013 |
The ZZ domain of dystrophin in DMD: making sense of missense mutations.
Topics: Actins; Animals; Aspartic Acid; Cysteine; Dystroglycans; Dystrophin; Genetic Variation; Humans; Mice; Mice, Transgenic; Muscular Dystrophy, Duchenne; Mutation, Missense; Protein Folding; Protein Stability; Zinc Fingers | 2014 |
Cysteine mutagenesis reveals alternate proximity between transmembrane domain 2 and hairpin loop 1 of the glutamate transporter EAAT1.
Topics: Amino Acid Sequence; Aspartic Acid; Cadmium Chloride; Cross-Linking Reagents; Cysteine; Dithiothreitol; Excitatory Amino Acid Transporter 1; Glutamic Acid; HeLa Cells; Humans; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Phenanthrolines; Protein Structure, Tertiary; Structure-Activity Relationship | 2014 |
Interaction of the CLPFFD peptide with gold nanospheres. A Raman, surface enhanced Raman scattering and theoretical study.
Topics: Amyloid beta-Peptides; Aspartic Acid; Cysteine; Gold; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Metal Nanoparticles; Models, Molecular; Nanospheres; Peptides; Phenylalanine; Protein Conformation; Spectrophotometry, Ultraviolet; Spectrum Analysis, Raman | 2015 |
Quantum mechanics/molecular mechanics modeling of covalent addition between EGFR-cysteine 797 and N-(4-anilinoquinazolin-6-yl) acrylamide.
Topics: Acrylamides; Aspartic Acid; Catalytic Domain; Cysteine; ErbB Receptors; Models, Molecular; Molecular Dynamics Simulation; Protein Conformation; Quantum Theory; Quinazolines | 2015 |
In Vitro Study of L-Glutamate and L-Glutamine Transport in Retinal Pericytes: Involvement of Excitatory Amino Acid Transporter 1 and Alanine-Serine-Cysteine Transporter 2.
Topics: Alanine; Amino Acid Transport System ASC; Animals; Aspartic Acid; Cysteine; Excitatory Amino Acid Transporter 1; Glutamic Acid; Glutamine; Ion Transport; Male; Minor Histocompatibility Antigens; Pericytes; Rats, Wistar; Retina; Serine | 2015 |
Defining Multiple Characteristic Raman Bands of α-Amino Acids as Biomarkers for Planetary Missions Using a Statistical Method.
Topics: Alanine; Aspartic Acid; Atmosphere; Cysteine; Earth, Planet; Exobiology; Extraterrestrial Environment; Glutamine; Glycine; Humans; Mars; Models, Statistical; Space Simulation; Spacecraft; Spectrum Analysis, Raman | 2016 |
A unified mechanism for proteolysis and autocatalytic activation in the 20S proteasome.
Topics: Aspartic Acid; Autolysis; Catalysis; Catalytic Domain; Crystallography, X-Ray; Cysteine; Lysine; Mutagenesis, Site-Directed; Proteasome Endopeptidase Complex; Protein Precursors; Proteolysis; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Serine; Threonine | 2016 |
Reversible oxidation controls the activity and oligomeric state of the mammalian phosphoglycolate phosphatase AUM.
Topics: Animals; Aspartic Acid; Catalysis; Catalytic Domain; Cysteine; Disulfides; Hydrogen Peroxide; Hydrolases; Mice; Oxidation-Reduction; Oxidative Stress; Phosphoric Monoester Hydrolases; Reactive Oxygen Species; Signal Transduction | 2016 |
Impact of charged amino acid substitution in the transmembrane domain of L-alanine exporter, AlaE, of Escherichia coli on the L-alanine export.
Topics: Alanine; Amino Acid Motifs; Amino Acid Substitution; Amino Acid Transport Systems, Neutral; Arginine; Aspartic Acid; Biological Transport; Cysteine; Escherichia coli; Escherichia coli Proteins; Membrane Transport Proteins; Mutagenesis, Site-Directed; Protein Domains | 2017 |
Structural basis of haem-iron acquisition by fungal pathogens.
Topics: Aspartic Acid; Biological Transport; Candida albicans; Crystallography, X-Ray; Cysteine; Fungal Proteins; Heme; Hemeproteins; Histidine; Iron; Membrane Proteins; Molecular Conformation | 2016 |
Transport of BMAA into Neurons and Astrocytes by System x
Topics: Amino Acid Transport Systems; Amino Acids, Diamino; Animals; Aspartic Acid; Astrocytes; Carbon Isotopes; Cells, Cultured; Cerebral Cortex; Cyanobacteria Toxins; Cysteine; Embryo, Mammalian; Female; Glutamic Acid; Glutathione; Mice; Neurons; Neurotransmitter Uptake Inhibitors; Pregnancy; Sulfasalazine; Time Factors | 2018 |
Theoretical insights into the protonation states of active site cysteine and citrullination mechanism of Porphyromonas gingivalis peptidylarginine deiminase.
Topics: Amino Acid Motifs; Arginine; Aspartic Acid; Bacterial Proteins; Binding Sites; Catalytic Domain; Citrulline; Crystallography, X-Ray; Cysteine; Histidine; Hydrolases; Hydrolysis; Molecular Dynamics Simulation; Porphyromonas gingivalis; Protein Binding; Protein Conformation, alpha-Helical; Protein Conformation, beta-Strand; Protein Interaction Domains and Motifs; Protein-Arginine Deiminases; Protons; Quantum Theory; Substrate Specificity; Thermodynamics | 2017 |
Comparative Effects of Hydrogen Sulfide-Releasing Compounds on [
Topics: Animals; Aspartic Acid; Cattle; Cysteine; D-Aspartic Acid; Hydrogen; Hydrogen Sulfide; Retina; Sulfides | 2018 |
Chemical Cleavage of an Asp-Cys Sequence Allows Efficient Production of Recombinant Peptides with an N-Terminal Cysteine Residue.
Topics: Acids; Amino Acid Sequence; Apolipoproteins B; Aspartic Acid; Cell-Penetrating Peptides; Cysteine; Escherichia coli; Humans; Hydrolysis; Peptides; Recombinant Fusion Proteins; Thrombin; Tumor Suppressor Protein p53 | 2018 |
Intra-electron transfer induced by protonation in copper-containing nitrite reductase.
Topics: Aspartic Acid; Catalytic Domain; Copper; Crystallography, X-Ray; Cysteine; Electrons; Histidine; Kinetics; Nitrite Reductases; Nitrites; Oxidation-Reduction; Protein Conformation; Protons | 2018 |
Cysteine Scanning Mutagenesis of TM4b-4c Loop of Glutamate Transporter EAAT1 Reveals Three Conformationally Sensitive Residues.
Topics: Amino Acid Transport System X-AG; Animals; Aspartic Acid; Biological Transport; Cysteine; Excitatory Amino Acid Transporter 1; Glutamic Acid; HeLa Cells; Humans; Mutagenesis; Potassium; Protein Structure, Secondary; Rats; Structure-Activity Relationship; Tetraspanins | 2018 |
Interhelical interactions between D92 and C218 in the cytoplasmic domain regulate proton uptake upon N-decay in the proton transport of Acetabularia rhodopsin II.
Topics: Acetabularia; Aspartic Acid; Cysteine; Hydrogen Bonding; Hydrogen-Ion Concentration; Kinetics; Light; Photolysis; Protein Domains; Protons; Rhodopsin; Spectrophotometry | 2018 |
Investigation on side-product formation during the synthesis of a lactoferrin-derived lactam-bridged cyclic peptide.
Topics: Animals; Aspartic Acid; Cattle; Cyclization; Cysteine; Lactams; Lactoferrin; Peptides, Cyclic | 2018 |
Metabolic profiles of cysteine, methionine, glutamate, glutamine, arginine, aspartate, asparagine, alanine and glutathione in Streptococcus thermophilus during pH-controlled batch fermentations.
Topics: Alanine; Amino Acids; Arginine; Asparagine; Aspartic Acid; Culture Media; Cysteine; Fermentation; Glutamic Acid; Glutamine; Glutathione; Hydrogen-Ion Concentration; Metabolic Networks and Pathways; Metabolome; Methionine; Nitrogen; Streptococcus thermophilus | 2018 |
Impacts of Cys392, Asp393, and ATP on the FAD Binding, Photoreduction, and the Stability of the Radical State of Chlamydomonas reinhardtii Cryptochrome.
Topics: Adenosine Triphosphate; Amino Acid Substitution; Aspartic Acid; Chlamydomonas reinhardtii; Cryptochromes; Cysteine; Flavin-Adenine Dinucleotide; Light; Oxidation-Reduction; Protein Binding; Protein Stability | 2019 |
Reactivity of Gold(I) Monocarbene Complexes with Protein Targets: A Theoretical Study.
Topics: Arginine; Aspartic Acid; Binding Sites; Catalysis; Coordination Complexes; Cysteine; Glutamine; Gold; Methane; Models, Theoretical; Protein Binding; Proteins; Thermodynamics | 2019 |
Protein Arginine Deiminases (PADs): Biochemistry and Chemical Biology of Protein Citrullination.
Topics: Animals; Aspartic Acid; Catalysis; Catalytic Domain; Citrullination; Cysteine; Enzyme Inhibitors; HEK293 Cells; Histidine; Humans; Mice; Models, Chemical; Mutation; Protein Processing, Post-Translational; Protein-Arginine Deiminases; Proteins | 2019 |
Study on the cellular internalization mechanisms and
Topics: Animals; Arginine; Aspartic Acid; Bone Neoplasms; Cell Line, Tumor; Cell Movement; Cell Survival; Cysteine; Genetic Vectors; Male; Membrane Proteins; Mice; Mice, Inbred BALB C; Nanoparticles; Particle Size; Peptide Fragments; Peptide T; Polyethylene Glycols; Prostatic Neoplasms; Tumor Burden | 2020 |
Structure and dynamics at N- and C-terminal regions of intrinsically disordered human c-Myc PEST degron reveal a pH-induced transition.
Topics: Amino Acid Sequence; Aspartic Acid; Cloning, Molecular; Cysteine; Escherichia coli; Gene Expression; Genetic Vectors; Glutamic Acid; Humans; Hydrogen-Ion Concentration; Indoles; Intrinsically Disordered Proteins; Molecular Dynamics Simulation; Neoplasm Proteins; Phosphatidylcholines; Protein Folding; Protein Structure, Secondary; Proto-Oncogene Proteins c-myc; Recombinant Proteins; Spectrometry, Fluorescence; Staining and Labeling; Tryptophan | 2020 |
Methods to Study the Structure and Catalytic Activity of cis-Splicing Inteins.
Topics: Aspartic Acid; Biocatalysis; Biochemistry; Carbon Isotopes; Cysteine; Electrophoresis, Polyacrylamide Gel; Escherichia coli; Exteins; Gene Expression; Genetic Vectors; Histidine; Hydrogen-Ion Concentration; Inteins; Maltose-Binding Proteins; Nitrogen Isotopes; Nuclear Magnetic Resonance, Biomolecular; Protein Splicing; Recombinant Fusion Proteins | 2020 |
Colorimetric determination of cysteine by a paper-based assay system using aspartic acid modified gold nanoparticles.
Topics: Aspartic Acid; Carbohydrate Sequence; Cell Phone; Colorimetry; Cysteine; Gold; Humans; Limit of Detection; Metal Nanoparticles; Paper; Software | 2020 |
C1188D mutation abolishes specific recognition between MLL1-CXXC domain and CpG site by inducing conformational switch of flexible N-terminal.
Topics: Amino Acid Substitution; Aspartic Acid; Binding Sites; CpG Islands; Cysteine; DNA; Histone-Lysine N-Methyltransferase; Humans; Molecular Dynamics Simulation; Mutation; Myeloid-Lymphoid Leukemia Protein; Nucleic Acid Conformation; Protein Binding; Protein Conformation, alpha-Helical; Protein Conformation, beta-Strand; Protein Interaction Domains and Motifs; Static Electricity; Thermodynamics | 2020 |
Metabolic pathway alterations in microvascular endothelial cells in response to hypoxia.
Topics: Amino Acids; Aspartic Acid; Cell Hypoxia; Cell Line; Cysteine; Endothelial Cells; HEK293 Cells; Humans; Metabolic Networks and Pathways; Microvessels; Nucleotides | 2020 |
A Dense Layer of Polyethyleneglycol and Zwitterionic Bone Targeting Peptide on the Surface of Stereocomplex Polylactide-Polyethyleneglycol Nanoparticles Improves Shelf-storage Stability and the Serum Compatibility.
Topics: Animals; Aspartic Acid; Cysteine; Hydroxyapatites; Lysine; Mice; Nanoparticles; Peptides; Polyesters; Polyethylene Glycols; Protein Corona; Tamoxifen | 2022 |
Oligomeric state of the aspartate:alanine transporter from Tetragenococcus halophilus.
Topics: Alanine; Antiporters; Aspartic Acid; Cysteine; Enterococcaceae; Glutamates; Membrane Transport Proteins; Succinates | 2022 |
Coronaviruses exploit a host cysteine-aspartic protease for replication.
Topics: Animals; Apoptosis; Aspartic Acid; Caspase 6; Coronavirus; Coronavirus Infections; Coronavirus Nucleocapsid Proteins; Cricetinae; Cysteine; Dipeptidyl Peptidase 4; Host-Pathogen Interactions; Humans; Interferons; Lung; Mesocricetus; Mice; Middle East Respiratory Syndrome Coronavirus; SARS-CoV-2; Severe acute respiratory syndrome-related coronavirus; Survival Rate; Virus Replication; Weight Loss | 2022 |
Discovery of an ʟ-amino acid ligase implicated in Staphylococcal sulfur amino acid metabolism.
Topics: Adenosine Triphosphate; Aspartic Acid; Bacterial Proteins; Cysteine; Dipeptides; Methionine; Peptide Synthases; Phylogeny; Staphylococcus aureus | 2022 |
Rapid, sensitive analysis method for determining the nitrogen stable isotope ratio of total free amino acids in soil.
Topics: Alanine; Amino Acids; Arginine; Asparagine; Aspartic Acid; Cysteine; gamma-Aminobutyric Acid; Glutamic Acid; Glycine; Histidine; Leucine; Lysine; Nitrogen; Nitrogen Isotopes; Phenylalanine; Serine; Soil; Tryptophan | 2022 |
Nontargeted metabolomic analysis to unravel alleviation mechanisms of carbon nanotubes on inhibition of alfalfa growth under pyrene stress.
Topics: Alanine; Aspartic Acid; Cysteine; Glutamates; Glyoxylates; Medicago sativa; Nanotubes, Carbon; Polycyclic Aromatic Hydrocarbons; Pyrenes; Sand; Soil; Soil Pollutants | 2022 |
Interactions between dopamine transporter and N-methyl-d-aspartate receptor-related amino acids on cognitive impairments in schizophrenia.
Topics: Amino Acids; Arginine; Aspartic Acid; Cognitive Dysfunction; Corpus Striatum; Cysteine; Dopamine; Dopamine Plasma Membrane Transport Proteins; gamma-Aminobutyric Acid; Glutamates; Humans; Methionine; Receptors, N-Methyl-D-Aspartate; Schizophrenia; Tomography, Emission-Computed, Single-Photon; Tropanes | 2022 |
Conformational transition induced in the aspartate:alanine antiporter by L-Ala binding.
Topics: Alanine; Antiporters; Aspartic Acid; Binding Sites; Cysteine; Fluorescent Dyes; Lactic Acid; Liposomes; Maleimides; Protein Conformation | 2022 |
Differential sensitivity of metabolic pathways in sugar beet roots to combined salt, heat, and light stress.
Topics: Aspartic Acid; Beta vulgaris; Chlorides; Citric Acid; Cysteine; gamma-Aminobutyric Acid; Gene Expression Regulation, Plant; Glucose; Hot Temperature; Mannitol; Metabolic Networks and Pathways; Plant Roots; Proline; Salinity; Salts; Sodium Chloride; Stress, Physiological; Sugars; Tryptophan; Tyrosine | 2022 |
Light-driven proton transmembrane transport enabled by bio-semiconductor 2D membrane: A general peptide-induced WS
Topics: Aspartic Acid; Biosensing Techniques; Cysteine; Ion Transport; Lysine; Peptides; Protons; Semiconductors | 2022 |
Separation of the enantiomers of underivatized amino acids by using serially connected dual column high-performance liquid chromatography-tandem mass spectrometry.
Topics: Acetonitriles; Amines; Amino Acids; Aspartic Acid; Chromatography, High Pressure Liquid; Chromatography, Liquid; Crown Ethers; Cysteine; Ethanol; Humans; Methionine; Phenylalanine; Proline; Serine; Stereoisomerism; Tandem Mass Spectrometry; Water | 2022 |
The relationship between islet β-cell function and metabolomics in overweight patients with Type 2 diabetes.
Topics: Adult; Aspartic Acid; Blood Glucose; Body Mass Index; Cross-Sectional Studies; Cysteine; Diabetes Mellitus, Type 2; Humans; Insulin; Insulin Resistance; Metabolomics; Overweight | 2023 |
Ferrihydrite synthesis in the presence of amino acids and artificial seawater.
Topics: Adsorption; Amino Acids; Aspartic Acid; Cysteine; Ferric Compounds; Glycine; Iron; Lysine; Methionine; Minerals; Seawater; Spectroscopy, Fourier Transform Infrared; Water | 2023 |
Standardized ileal digestibility of amino acids in cottonseed meal fed to pregnant and non-pregnant sows.
Topics: Amino Acids; Animal Feed; Animal Nutritional Physiological Phenomena; Animals; Aspartic Acid; Cottonseed Oil; Cysteine; Diet; Digestion; Female; Glycine max; Ileum; Methionine; Pregnancy; Serine; Swine; Threonine; Tyrosine | 2023 |
Trichloroethylene Metabolite
Topics: Amino Acids; Aspartic Acid; Colforsin; Cysteine; Female; Humans; Matrix Metalloproteinase 2; Oleic Acids; Placenta; Pregnancy; Trichloroethylene; Trophoblasts | 2023 |
Dietary amino acids and anthropometric indices: Tehran Lipid and Glucose Study.
Topics: Adult; Amino Acids; Aspartic Acid; Body Mass Index; Cysteine; Glutamates; Humans; Iran; Lipids; Lysine; Obesity; Overweight; Risk Factors; Tryptophan; Waist Circumference | 2023 |
XCP1 cleaves Pathogenesis-related protein 1 into CAPE9 for systemic immunity in Arabidopsis.
Topics: Animals; Arabidopsis; Arabidopsis Proteins; Aspartic Acid; Caspases; Cysteine; Cysteine Proteases; Humans; Peptide Hydrolases; Plant Immunity; Salicylic Acid; Xylem | 2023 |
[Moxibustion with seed-size moxa cone enhances anti-tumor effect of cyclophosphamide on Hepa1-6 hepatoma-bearing mice by regulating apoptosis factor cysteine family].
Topics: Animals; Apoptosis; Aspartic Acid; Body Weight; Carcinoma, Hepatocellular; Caspase 3; Caspase 9; Cyclophosphamide; Cysteine; Interleukin-2; Interleukin-4; Liver Neoplasms; Male; Mice; Mice, Inbred C57BL; Moxibustion; Quality of Life; RNA, Messenger; Tumor Necrosis Factor-alpha | 2023 |
[Effect of aqueous extract of Corni Fructus on Aβ_(25-35)-induced brain injury and neuroinflammation in mice with Alzheimer's disease].
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Aspartic Acid; Brain Injuries; Cornus; Cysteine; Disease Models, Animal; Interleukin-6; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Molecular Docking Simulation; Neuroinflammatory Diseases; Peptide Hydrolases; Tumor Necrosis Factor-alpha | 2023 |
Quantitative structure-activity relationships of the bitter thresholds of amino acids, peptides, and their derivatives.
Topics: Amino Acids; Humans; Mathematics; Peptides; Structure-Activity Relationship; Taste | 1987 |
Expression cloning of a Na+-independent aromatic amino acid transporter with structural similarity to H+/monocarboxylate transporters.
Topics: Amino Acid Sequence; Amino Acid Transport Systems; Amino Acid Transport Systems, Neutral; Animals; Anion Transport Proteins; Bacterial Proteins; Carrier Proteins; Cloning, Molecular; Escherichia coli Proteins; Female; Intestine, Small; Kinetics; Levodopa; Mice; Molecular Sequence Data; Oocytes; Phenylalanine; Rats; Recombinant Proteins; Sequence Alignment; Sequence Homology, Amino Acid; Substrate Specificity; Tryptophan; Tyrosine; Xenopus laevis | 2001 |