cysteine has been researched along with alpha-synuclein in 27 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 9 (33.33) | 29.6817 |
| 2010's | 12 (44.44) | 24.3611 |
| 2020's | 6 (22.22) | 2.80 |
| Authors | Studies |
|---|---|
| Berger, K; Holzmann, C; Krüger, R; Riess, O; Saecker, AM; Schmitt, I; Schöls, L | 1 |
| Freed, CR; Zhou, W | 1 |
| Chen, J; Der-Sarkissian, A; Jao, CC; Langen, R | 1 |
| Abeliovich, A; Jonason, A; Leete, T; Martinat, C; Shendelman, S | 1 |
| Dohmae, N; Goedert, M; Hasegawa, M; Hisanaga, S; Masuda, M; Nonaka, T; Oikawa, T | 1 |
| Bertoncini, CW; Jares-Erijman, EA; Jovin, TM; Klement, R; Roberti, MJ | 1 |
| Banerjee, R; Ciborowski, P; Garg, SK; Gendelman, HE; Glanzer, JG; Kadiu, I; Nordgren, T; Reynolds, AD | 1 |
| Kerk, SY; Lim, TM; Xiong, GG; Zhou, ZD | 1 |
| Cookson, MR; Fredenburg, RA; Grammatopoulos, TN; Lansbury, PT; Liu, Y; Liu, Z; Logan, T; Meray, RK | 1 |
| Clark, L; Logan, T; Ray, SS | 1 |
| Bähr, M; Garrido, M; Kügler, S; Taschenberger, G; Tereshchenko, Y; Zhevtsova, Z | 1 |
| Chang, JY; Hong, DP; Jiang, C; Xiong, W | 1 |
| Lokappa, SB; Ulmer, TS | 1 |
| Jares-Erijman, E; Jovin, TM; Roberti, MJ | 1 |
| Caldwell, GA; Chen, SG; Johnson, WM; Mieyal, JJ; Siedlak, SL; Wang, W; Wilson-Delfosse, AL; Yao, C; Zhu, X | 1 |
| Lee, JC; McGlinchey, RP | 1 |
| Barinova, K; Khomyakova, E; Muronetz, V; Schmalhausen, E; Semenyuk, P | 1 |
| Cistrone, PA; Dawson, PE; Deniz, AA; Lee, TC; Moran, CR | 1 |
| Chen, R; Gao, G; He, M; Li, J; Sun, T; Wang, L | 1 |
| Banerji, B; Chatterjee, S; Chattopadhyay, K; Das Saha, K; Ghosh, S; Mishra, S | 1 |
| Huffer, KE; Lacy, SM; Lee, JC; McGlinchey, RP; Sidransky, E; Tayebi, N | 1 |
| Galesic, A; Pratt, MR | 1 |
| Butler, NJM; Fong, R; Ghosh, S; Huynh, A; Manfredsson, FP; Moss, A; Pan, J; Sanchez, J; Swanson, RA; Wang, J; Won, SJ; Wong, C; Wu, L | 1 |
| Atieh, TB; Baum, J; Hoop, CL; Roth, J; Yang, X | 1 |
| Ha, Y; Kwon, Y; Nam, EJ; Paik, SR; Park, H | 1 |
| Kashina, A; Pan, B; Petersson, EJ; Rhoades, E; Shimogawa, M; Zhao, J | 1 |
| Medvedeva, MV; Muronetz, VI; Pozdyshev, DV; Sevostyanova, IA | 1 |
1 review(s) available for cysteine and alpha-synuclein
| Article | Year |
|---|---|
Potential Effect of Post-Transcriptional Substitutions of Tyrosine for Cysteine Residues on Transformation of Amyloidogenic Proteins.
Topics: alpha-Synuclein; Amyloidogenic Proteins; Codon; Cysteine; Escherichia coli; Humans; Tyrosine | 2022 |
26 other study(ies) available for cysteine and alpha-synuclein
| Article | Year |
|---|---|
Polymorphisms of the alpha-synuclein promoter: expression analyses and association studies in Parkinson's disease.
Topics: Aged; alpha-Synuclein; Cell Culture Techniques; Cysteine; Enzyme-Linked Immunosorbent Assay; Female; Gene Expression Regulation; Genes, Reporter; Glycine; Haplotypes; Humans; Male; Middle Aged; Nerve Tissue Proteins; Neuroblastoma; Parkinson Disease; Polymerase Chain Reaction; Polymorphism, Genetic; Polymorphism, Single-Stranded Conformational; Promoter Regions, Genetic; Synucleins; Threonine; Transfection | 2003 |
Tyrosine-to-cysteine modification of human alpha-synuclein enhances protein aggregation and cellular toxicity.
Topics: Adenoviridae; alpha-Synuclein; Animals; Apoptosis; beta-Synuclein; Blotting, Western; Cell Line; Cell Survival; Cloning, Molecular; Cysteine; Detergents; Dimerization; Electrophoresis, Polyacrylamide Gel; Humans; Immunohistochemistry; Magnetic Resonance Spectroscopy; Mice; Microscopy, Fluorescence; Mutagenesis, Site-Directed; Mutation; Nerve Tissue Proteins; Neurons; Nitrogen; Octoxynol; Oxidative Stress; Oxygen; Phenylalanine; Plasmids; Protein Binding; Proteins; Rats; Recombinant Proteins; Synucleins; Time Factors; Transfection; Tyrosine | 2004 |
Structure of membrane-bound alpha-synuclein studied by site-directed spin labeling.
Topics: alpha-Synuclein; Amino Acid Sequence; Cell Membrane; Cysteine; Electron Spin Resonance Spectroscopy; Humans; Molecular Sequence Data; Nerve Tissue Proteins; Neurodegenerative Diseases; Protein Structure, Secondary; Spin Labels; Synucleins | 2004 |
DJ-1 is a redox-dependent molecular chaperone that inhibits alpha-synuclein aggregate formation.
Topics: alpha-Synuclein; Antioxidants; Cell Differentiation; Cell Line, Tumor; Cysteine; Cytoplasm; Dimerization; Dopamine; Genetic Vectors; HeLa Cells; Homozygote; Humans; Intracellular Signaling Peptides and Proteins; Molecular Chaperones; Mutation; Neurons; Oncogene Proteins; Oxidation-Reduction; Oxidative Stress; Oxygen; Parkinson Disease; Protein Deglycase DJ-1; Spectrophotometry; Synucleins | 2004 |
Cysteine misincorporation in bacterially expressed human alpha-synuclein.
Topics: alpha-Synuclein; Amino Acid Sequence; Amino Acid Substitution; Cloning, Molecular; Cysteine; Dimerization; Escherichia coli; Humans; Mutagenesis, Site-Directed; Protein Biosynthesis | 2006 |
Fluorescence imaging of amyloid formation in living cells by a functional, tetracysteine-tagged alpha-synuclein.
Topics: alpha-Synuclein; Amyloid; Biosensing Techniques; Cell Line, Tumor; Cysteine; Escherichia coli; Fluorescence Resonance Energy Transfer; Fluorescent Dyes; Genetic Vectors; Humans; Microscopy, Confocal; Microscopy, Fluorescence; Oxidative Stress; Reactive Oxygen Species; Recombinant Fusion Proteins; Transfection | 2007 |
Nitrated alpha-synuclein and microglial neuroregulatory activities.
Topics: alpha-Synuclein; Animals; Cathepsin B; Cells, Cultured; Cystatins; Cysteine; Cytoskeletal Proteins; Dopamine; Gene Expression Regulation; Glutamic Acid; Glutathione; Mice; Mice, Inbred C57BL; Microglia; Nerve Tissue Proteins; NF-kappa B; Nitrates; Oxidation-Reduction; Oxidative Stress; Parkinson Disease; Protein Array Analysis; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Tandem Mass Spectrometry | 2008 |
Dopamine auto-oxidation aggravates non-apoptotic cell death induced by over-expression of human A53T mutant alpha-synuclein in dopaminergic PC12 cells.
Topics: Acetylcysteine; alpha-Synuclein; Animals; Benzimidazoles; Cell Death; Chromatography, High Pressure Liquid; Cysteine; Dopamine; Enzyme Inhibitors; Flow Cytometry; Fluorescent Dyes; Free Radical Scavengers; Glutathione; Humans; Monophenol Monooxygenase; Mutation; Nerve Growth Factor; Oxidation-Reduction; PC12 Cells; Rats; Tetrazolium Salts; Thiazoles; Transfection | 2009 |
Membrane-associated farnesylated UCH-L1 promotes alpha-synuclein neurotoxicity and is a therapeutic target for Parkinson's disease.
Topics: alpha-Synuclein; Animals; Brain; Cell Line, Tumor; Cell Membrane; Chlorocebus aethiops; COS Cells; Cysteine; Endoplasmic Reticulum; Humans; Intracellular Membranes; Methionine; Mice; Neurons; Parkinson Disease; Prenylation; Proteasome Endopeptidase Complex; Protein Binding; Ubiquitin Thiolesterase | 2009 |
Engineered disulfide bonds restore chaperone-like function of DJ-1 mutants linked to familial Parkinson's disease.
Topics: alpha-Synuclein; Cysteine; Genetic Diseases, Inborn; Humans; Intracellular Signaling Peptides and Proteins; Molecular Chaperones; Mutation; Oncogene Proteins; Parkinson Disease; Protein Deglycase DJ-1; Protein Structure, Tertiary; Proteins | 2010 |
Glutathione depletion and overproduction both initiate degeneration of nigral dopaminergic neurons.
Topics: alpha-Synuclein; Analysis of Variance; Animals; Apomorphine; Catalytic Domain; Cell Survival; Cysteine; Disease Models, Animal; Dopamine; Dopamine Agonists; Female; Gene Expression Regulation; Gliosis; Glutathione; Glutathione Reductase; Green Fluorescent Proteins; Movement; Nerve Degeneration; Rats; Rats, Wistar; RNA, Small Interfering; Sensation Disorders; Stereotyped Behavior; Substantia Nigra; Time Factors; Transduction, Genetic; Tyrosine 3-Monooxygenase; Vesicular Monoamine Transport Proteins | 2011 |
The role of the C-terminus of human α-synuclein: intra-disulfide bonds between the C-terminus and other regions stabilize non-fibrillar monomeric isomers.
Topics: alpha-Synuclein; Benzothiazoles; Circular Dichroism; Cysteine; Cystine; Fluorescent Dyes; Humans; Isomerism; Kinetics; Mutagenesis, Site-Directed; Mutant Proteins; Oxidation-Reduction; Parkinson Disease; Protein Denaturation; Protein Folding; Protein Stability; Protein Structure, Secondary; Recombinant Proteins; Spectrometry, Fluorescence; Thiazoles | 2011 |
Alpha-synuclein populates both elongated and broken helix states on small unilamellar vesicles.
Topics: alpha-Synuclein; Amino Acid Sequence; Calorimetry; Cell Membrane; Circular Dichroism; Cysteine; Humans; Molecular Sequence Data; Protein Binding; Protein Conformation; Protein Folding; Protein Structure, Secondary; Temperature; Thermodynamics; Unilamellar Liposomes | 2011 |
Confocal fluorescence anisotropy and FRAP imaging of α-synuclein amyloid aggregates in living cells.
Topics: Algorithms; alpha-Synuclein; Amyloid; Cell Line, Tumor; Cysteine; Fluorescence; Fluorescence Polarization; Fluorescence Recovery After Photobleaching; Fluorescent Dyes; Humans; Kinetics; Microscopy, Confocal; Mutation; Recombinant Fusion Proteins; Single-Cell Analysis; Transfection | 2011 |
Glutaredoxin deficiency exacerbates neurodegeneration in C. elegans models of Parkinson's disease.
Topics: alpha-Synuclein; Animals; Caenorhabditis elegans; Cell Survival; Cysteine; Disease Models, Animal; Dopaminergic Neurons; Evolution, Molecular; Gene Expression Regulation; Glutaredoxins; Helminth Proteins; Homeostasis; Humans; Leucine-Rich Repeat Serine-Threonine Protein Kinase-2; Mesencephalon; Oxidative Stress; Parkinson Disease; Phenotype; Protein Serine-Threonine Kinases; RNA, Messenger; Tyrosine 3-Monooxygenase | 2015 |
Cysteine cathepsins are essential in lysosomal degradation of α-synuclein.
Topics: alpha-Synuclein; Animals; Brain; Cathepsin B; Cathepsin D; Cathepsin L; Chromatography, Liquid; Circular Dichroism; Cysteine; Humans; Liver; Lysosomes; Mass Spectrometry; Mice; Neurodegenerative Diseases; Parkinson Disease; Peptide Mapping; Peptides; Phospholipids | 2015 |
Binding of alpha-synuclein to partially oxidized glyceraldehyde-3-phosphate dehydrogenase induces subsequent inactivation of the enzyme.
Topics: alpha-Synuclein; Amyloid; Catalysis; Catalytic Domain; Cysteine; Enzyme Stability; Enzyme-Linked Immunosorbent Assay; Glyceraldehyde-3-Phosphate Dehydrogenases; Glycolysis; Humans; Immunoprecipitation; Molecular Dynamics Simulation; Oxidation-Reduction; Protein Binding; Scattering, Radiation; Ultracentrifugation | 2018 |
Site-Specific Three-Color Labeling of α-Synuclein via Conjugation to Uniquely Reactive Cysteines during Assembly by Native Chemical Ligation.
Topics: alpha-Synuclein; Color; Cysteine; Fluorescence Resonance Energy Transfer; Fluorescent Dyes; Humans; Maleimides; Protein Conformation | 2018 |
Gold nanoclusters for Parkinson's disease treatment.
Topics: alpha-Synuclein; Animals; Antiparkinson Agents; Cysteine; Disease Models, Animal; Gold; Male; Mice, Inbred C57BL; Nanoparticles; Parkinson Disease; PC12 Cells; Rats | 2019 |
Efficient Detection of Early Events of α-Synuclein Aggregation Using a Cysteine Specific Hybrid Scaffold.
Topics: alpha-Synuclein; Cell Proliferation; Cysteine; Fluorescent Dyes; Humans; Neuroblastoma; Protein Multimerization; Small Molecule Libraries; Tumor Cells, Cultured | 2019 |
C-terminal α-synuclein truncations are linked to cysteine cathepsin activity in Parkinson's disease.
Topics: alpha-Synuclein; Amyloid; Animals; Cathepsin B; Cathepsin L; Cysteine; Dopaminergic Neurons; Humans; Lysosomes; Mice; Mice, Inbred C57BL; Mice, Transgenic; Mutation; Parkinson Disease; Protein Aggregation, Pathological; Rats | 2019 |
Investigating the Effects of O-GlcNAc Modifications in Parkinson's Disease Using Semisynthetic α-Synuclein.
Topics: Acetylglucosamine; alpha-Synuclein; Cysteine; Escherichia coli; Esters; Gene Expression; Glycosylation; Humans; Parkinson Disease; Peptide Biosynthesis; Peptides; Plasmids; Protein Engineering; Recombinant Proteins; Solid-Phase Synthesis Techniques; Sulfhydryl Compounds; Threonine | 2020 |
α-synuclein aggregates induce c-Abl activation and dopaminergic neuronal loss by a feed-forward redox stress mechanism.
Topics: alpha-Synuclein; Animals; Cysteine; Dopamine; Dopaminergic Neurons; Mice; Oxidation-Reduction; Parkinson Disease; Substantia Nigra | 2021 |
DJ-1 Acts as a Scavenger of α-Synuclein Oligomers and Restores Monomeric Glycated α-Synuclein.
Topics: Acetylation; alpha-Synuclein; Cysteine; Glycation End Products, Advanced; Humans; Magnetic Resonance Spectroscopy; Neurons; Parkinson Disease; Protein Aggregation, Pathological; Protein Deglycase DJ-1; Protein Multimerization | 2021 |
Disulfide-Mediated Elongation of Amyloid Fibrils of α-Synuclein For Use in Producing Self-Healing Hydrogel and Dye-Absorbing Aerogel.
Topics: alpha-Synuclein; Amyloid; Cysteine; Disulfides; Hydrogels | 2022 |
Cysteine-Based Mimic of Arginylation Reproduces Neuroprotective Effects of the Authentic Post-Translational Modification on α-Synuclein.
Topics: alpha-Synuclein; Arginine; Cysteine; Neuroprotective Agents; Protein Processing, Post-Translational | 2022 |