cysteine has been researched along with 2,2-bis(hydroxymethyl)-1-azabicyclo(2,2,2,)octan-3-one in 2 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 0 (0.00) | 29.6817 |
2010's | 2 (100.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Amaro, RE; Baronio, R; Chen, CK; Chung, BP; Demir, Ö; Hall, LV; Hatfield, GW; Kaiser, P; Lathrop, RH; Lin, DW; Luecke, H; Richard Chamberlin, A; Salehi, F; Wallentine, BD; Wassman, CD | 1 |
Bykov, VJN; Wiman, KG; Zawacka-Pankau, J; Zhang, Q | 1 |
2 other study(ies) available for cysteine and 2,2-bis(hydroxymethyl)-1-azabicyclo(2,2,2,)octan-3-one
Article | Year |
---|---|
Computational identification of a transiently open L1/S3 pocket for reactivation of mutant p53.
Topics: Apoptosis Regulatory Proteins; Aza Compounds; Binding Sites; Bridged Bicyclo Compounds, Heterocyclic; Cell Line, Tumor; Computational Biology; Cyclin-Dependent Kinase Inhibitor p21; Cysteine; Heterocyclic Compounds, 4 or More Rings; Humans; Molecular Dynamics Simulation; Mutant Proteins; Oxepins; Protein Stability; Protein Structure, Secondary; Protein Structure, Tertiary; Proto-Oncogene Proteins; Reproducibility of Results; Structure-Activity Relationship; Transcription, Genetic; Tumor Suppressor Protein p53 | 2013 |
APR-246 reactivates mutant p53 by targeting cysteines 124 and 277.
Topics: Amino Acid Substitution; Aza Compounds; Bridged Bicyclo Compounds, Heterocyclic; Cell Line, Tumor; Cysteine; Humans; Mutation, Missense; Protein Domains; Protein Stability; Tumor Suppressor Protein p53 | 2018 |