cysteine has been researched along with (2-sulfonatoethyl)methanethiosulfonate in 53 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 7 (13.21) | 18.2507 |
| 2000's | 39 (73.58) | 29.6817 |
| 2010's | 7 (13.21) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Chen, JG; Rudnick, G; Sachpatzidis, A | 1 |
| Fleischhauer, R; Lehmann-Horn, F; Lerche, H; Malina, T; Mitrovic, N; Peter, W; Pika-Hartlaub, U | 1 |
| Karlin, A; Zhang, H | 1 |
| Desai, RR; Fahlke, C; George, AL; Rhodes, TH | 1 |
| Freedman, ND; Grant, M; Hawrot, E; McLaughlin, JT; Russin, TS; Spura, A | 1 |
| Ballesteros, JA; Chen, J; Chiappa, V; Javitch, JA; Simpson, MM | 1 |
| Chan, BS; Satriano, JA; Schuster, VL | 1 |
| del Camino, D; Holmgren, M; Liu, Y; Yellen, G | 1 |
| Deng, HB; Guang, W; Wang, JB | 1 |
| Biber, J; Forster, IC; Lambert, G; Murer, H | 1 |
| Hu, Y; Kaback, HR; Kwaw, I; Venkatesan, P | 1 |
| Hu, Y; Kaback, HR; Liu, Z; Venkatesan, P | 1 |
| Hu, Y; Kaback, HR; Venkatesan, P | 1 |
| Haddrill, J; Han, NL; Lynch, JW; Pierce, KD; Schofield, PR | 1 |
| Beck, C; Kuner, T; Sakmann, B; Seeburg, PH | 1 |
| Ding, PZ; Wilson, TH | 1 |
| Dawson, DC; Kriewall, TE; Liu, X; McCarty, NA; Smith, SS; Sun, F; Zhang, ZR | 1 |
| Cance, P; Counillon, L; Lazdunski, M; Lingueglia, E; Poët, M; Poujeol, P; Tauc, M | 1 |
| Haddrill, JL; Han, NL; Lynch, JW | 1 |
| Cappello, AR; Daddabbo, L; Miniero, DV; Natuzzi, D; Palmieri, F; Stipani, I; Stipani, V | 1 |
| Banderali, U; Garneau, L; Hobeila, F; Klein, H; Parent, L; Roux, B; Sauvé, R; Simoes, M | 1 |
| Giangregorio, N; Iacobazzi, V; Indiveri, C; Palmieri, F | 1 |
| Alexeyev, MF; Winkler, HH | 1 |
| Harvey, JR; Lang, RJ; Mulholland, EL | 1 |
| Ding, PZ | 1 |
| Garcia, ML; Lee, E; Mitchell, SM; Stephan, MM | 1 |
| Glomska, H; Keller, PC; Rudnick, G; Stephan, M | 1 |
| Bartlett, MC; Clarke, DM; Loo, TW | 1 |
| Horrigan, FT; Zhang, G | 1 |
| Engh, AM; Maduke, M | 1 |
| Rudnick, G; Zhang, YW | 1 |
| Christie, DL; Dodd, JR | 1 |
| Haska, CL; Hou, Z; Matherly, LH; Stapels, SE | 1 |
| McCarty, NA; Song, B; Zhang, ZR | 1 |
| Alexander, C; Borg, E; Dawson, DC; Liu, X; Serrano, J | 1 |
| Ermolova, N; Kaback, HR; Madhvani, RV | 1 |
| Armstrong, N; Beich-Frandsen, M; Gouaux, E; Jasti, J | 1 |
| Bhattacharyya, J; Enkvetchakul, D; Jeliazkova, I; Nichols, CG | 1 |
| Kubo, Y; Nakajo, K | 1 |
| Giangregorio, N; Indiveri, C; Palmieri, F; Tonazzi, A | 1 |
| Khantwal, CM; Swaan, PW | 1 |
| Liu, T; Lo, B; Silverman, M; Speight, P | 1 |
| Ding, J; Fliegel, L; Li, X; Rainey, JK; Reddy, T; Sykes, BD | 1 |
| Fatehi, M; Linsdell, P | 1 |
| Beaulieu, ME; Domazet, I; Escher, E; Guillemette, G; Holleran, BJ; Lavigne, P; Leduc, R; Yan, LP | 1 |
| Demsey, AF; Li, MS; Linsdell, P; Qi, J | 1 |
| Herz, K; Kozachkov, L; Olkhova, E; Padan, E; Rimon, A | 1 |
| Cui, J; Delaloye, K; Nekouzadeh, A; Rudy, Y; Wu, D; Zaydman, MA | 1 |
| Mese, G; Sánchez, HA; Srinivas, M; Verselis, VK; White, TW | 1 |
| Fliegel, L; Lee, BL; Sykes, BD; Tzeng, J | 1 |
| Furukawa, Y; Kodani, Y | 1 |
| Hwang, TC; Zhang, J | 1 |
| Dempski, RE; Richards, R | 1 |
53 other study(ies) available for cysteine and (2-sulfonatoethyl)methanethiosulfonate
| Article | Year |
|---|---|
The third transmembrane domain of the serotonin transporter contains residues associated with substrate and cocaine binding.
Topics: Asparagine; Binding Sites; Carrier Proteins; Cell Line; Cell Membrane; Cocaine; Cysteine; Ethyl Methanesulfonate; Humans; Indicators and Reagents; Isoleucine; Ligands; Membrane Glycoproteins; Membrane Transport Proteins; Mesylates; Mutagenesis, Site-Directed; Nerve Tissue Proteins; Protein Structure, Secondary; Serotonin; Serotonin Plasma Membrane Transport Proteins; Structure-Activity Relationship; Tyrosine | 1997 |
Role in fast inactivation of the IV/S4-S5 loop of the human muscle Na+ channel probed by cysteine mutagenesis.
Topics: Adult; Amino Acid Substitution; Cell Line; Cysteine; Embryo, Mammalian; Humans; Indicators and Reagents; Kidney; Kinetics; Mesylates; Models, Molecular; Mutagenesis, Site-Directed; Patch-Clamp Techniques; Protein Structure, Secondary; Sodium Channels; Sulfhydryl Reagents | 1997 |
Contribution of the beta subunit M2 segment to the ion-conducting pathway of the acetylcholine receptor.
Topics: Acetylcholine; Amino Acid Sequence; Amino Acid Substitution; Animals; Cysteine; Drug Synergism; Ethyl Methanesulfonate; Indicators and Reagents; Ion Channels; Mesylates; Mice; Molecular Sequence Data; Mutagenesis, Insertional; Protein Structure, Secondary; Receptor, Muscarinic M2; Receptors, Muscarinic | 1998 |
Pore stoichiometry of a voltage-gated chloride channel.
Topics: Cadmium; Cell Line; Chloride Channels; Cysteine; Electrochemistry; Histidine; Humans; Ion Channel Gating; Mesylates; Molecular Conformation; Muscle Proteins; Mutagenesis, Site-Directed; Phenanthrolines; Sulfhydryl Compounds | 1998 |
Probing the agonist domain of the nicotinic acetylcholine receptor by cysteine scanning mutagenesis reveals residues in proximity to the alpha-bungarotoxin binding site.
Topics: Acetylcholine; Animals; Bungarotoxins; Cysteine; Humans; Indicators and Reagents; Mesylates; Mice; Mutagenesis, Site-Directed; Nicotinic Agonists; Nicotinic Antagonists; Oxidation-Reduction; Peptide Fragments; Phenylalanine; Protein Binding; Receptors, Nicotinic; Torpedo; Tryptophan; Valine | 1999 |
Electrostatic and aromatic microdomains within the binding-site crevice of the D2 receptor: contributions of the second membrane-spanning segment.
Topics: Amino Acid Substitution; Aspartic Acid; Binding, Competitive; Cell Line; Cell Membrane; Cysteine; Dopamine Antagonists; Ethyl Methanesulfonate; Humans; Mesylates; Models, Molecular; Mutagenesis, Site-Directed; Peptide Fragments; Protein Binding; Protein Structure, Tertiary; Receptors, Dopamine D2; Static Electricity; Sulpiride | 1999 |
Mapping the substrate binding site of the prostaglandin transporter PGT by cysteine scanning mutagenesis.
Topics: Antiporters; Binding Sites; Cysteine; Dinoprostone; DNA-Binding Proteins; HeLa Cells; Humans; Mesylates; Mutagenesis, Site-Directed; Organic Anion Transporters; Protein Conformation; Substrate Specificity | 1999 |
Blocker protection in the pore of a voltage-gated K+ channel and its structural implications.
Topics: Bacterial Proteins; Cysteine; Hydrogen Bonding; Intracellular Signaling Peptides and Proteins; Ion Channel Gating; Mesylates; Models, Molecular; Peptides; Potassium; Potassium Channel Blockers; Potassium Channels; Protein Conformation; Protein Structure, Secondary; Quaternary Ammonium Compounds; Shaker Superfamily of Potassium Channels; Static Electricity; Tetraethylammonium | 2000 |
Selected cysteine residues in transmembrane domains of mu-opioid receptor are critical for effects of sulfhydryl reagents.
Topics: Alanine; Amino Acid Sequence; Amino Acid Substitution; Animals; CHO Cells; COS Cells; Cricetinae; Cysteine; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Ethyl Methanesulfonate; Humans; Ligands; Membranes; Mesylates; Molecular Sequence Data; Mutagenesis, Site-Directed; Naloxone; Narcotic Antagonists; Radioligand Assay; Receptors, Opioid, mu; Sulfhydryl Reagents | 2000 |
Cysteine residues and the structure of the rat renal proximal tubular type II sodium phosphate cotransporter (rat NaPi IIa).
Topics: Amino Acid Sequence; Amino Acid Substitution; Animals; Carrier Proteins; Cysteine; Disulfides; Ethyl Methanesulfonate; Kidney Tubules, Proximal; Mesylates; Methyl Methanesulfonate; Molecular Sequence Data; Mutagenesis, Site-Directed; Oocytes; Protein Structure, Tertiary; Rats; Reducing Agents; Serine; Sodium-Phosphate Cotransporter Proteins; Sodium-Phosphate Cotransporter Proteins, Type II; Sodium-Phosphate Cotransporter Proteins, Type IIa; Symporters; Xenopus laevis | 2000 |
Site-directed sulfhydryl labeling of the lactose permease of Escherichia coli: helix VII.
Topics: Amino Acid Sequence; Amino Acid Substitution; Cold Temperature; Cysteine; Escherichia coli; Escherichia coli Proteins; Ethylmaleimide; Hot Temperature; Membrane Proteins; Membrane Transport Proteins; Mesylates; Models, Molecular; Molecular Sequence Data; Monosaccharide Transport Proteins; Mutagenesis, Site-Directed; Protein Conformation; Protein Structure, Secondary; Sulfhydryl Reagents; Symporters | 2000 |
Site-directed sulfhydryl labeling of the lactose permease of Escherichia coli: N-ethylmaleimide-sensitive face of helix II.
Topics: Alanine; Amino Acid Sequence; Cold Temperature; Cysteine; Escherichia coli; Escherichia coli Proteins; Ethylmaleimide; Glycine; Hot Temperature; Leucine; Membrane Proteins; Membrane Transport Modulators; Membrane Transport Proteins; Mesylates; Models, Molecular; Molecular Sequence Data; Monosaccharide Transport Proteins; Mutagenesis, Site-Directed; Periplasm; Protein Structure, Secondary; Solvents; Sulfhydryl Reagents; Symporters | 2000 |
Site-directed sulfhydryl labeling of the lactose permease of Escherichia coli: helix X.
Topics: Amino Acid Sequence; Amino Acid Substitution; Ascorbic Acid; Cold Temperature; Cysteine; Escherichia coli; Escherichia coli Proteins; Ethylmaleimide; Hot Temperature; Ligands; Membrane Proteins; Membrane Transport Proteins; Mesylates; Methylphenazonium Methosulfate; Models, Molecular; Molecular Sequence Data; Monosaccharide Transport Proteins; Mutagenesis, Site-Directed; Protein Conformation; Protein Structure, Secondary; Sulfhydryl Reagents; Symporters | 2000 |
The surface accessibility of the glycine receptor M2-M3 loop is increased in the channel open state.
Topics: Amino Acid Substitution; Cell Line; Cysteine; Dithiothreitol; Dose-Response Relationship, Drug; Glycine; Humans; Ion Channel Gating; Kidney; Mesylates; Mutagenesis, Site-Directed; Patch-Clamp Techniques; Protein Binding; Protein Conformation; Receptors, Glycine; Reducing Agents; Reflex, Startle; Transfection | 2001 |
Channel-lining residues of the AMPA receptor M2 segment: structural environment of the Q/R site and identification of the selectivity filter.
Topics: Amino Acid Substitution; Animals; Calcium; Cysteine; Cytoplasm; Dose-Response Relationship, Drug; Ethyl Methanesulfonate; Glutamic Acid; Ion Channel Gating; Kainic Acid; Kinetics; Membrane Potentials; Mesylates; Microinjections; Mutagenesis, Site-Directed; Oocytes; Patch-Clamp Techniques; Permeability; Receptors, AMPA; Structure-Activity Relationship; Sulfhydryl Reagents; Xenopus laevis | 2001 |
The effect of modifications of the charged residues in the transmembrane helices on the transport activity of the melibiose carrier of Escherichia coli.
Topics: Amino Acid Sequence; Amino Acid Substitution; Cell Membrane; Cysteine; Escherichia coli; Ethyl Methanesulfonate; Hydrogen Peroxide; Kinetics; Melibiose; Membrane Transport Proteins; Mesylates; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Protein Structure, Secondary; Recombinant Proteins; Sulfhydryl Reagents; Symporters | 2001 |
CFTR: covalent and noncovalent modification suggests a role for fixed charges in anion conduction.
Topics: Animals; Anions; Arginine; Cysteine; Cystic Fibrosis Transmembrane Conductance Regulator; Disulfides; Electric Conductivity; Ethyl Methanesulfonate; Female; Humans; Hydrogen-Ion Concentration; Lysine; Membrane Potentials; Mercaptoethanol; Mesylates; Models, Biological; Oocytes; Patch-Clamp Techniques; Perfusion; Xenopus | 2001 |
Exploration of the pore structure of a peptide-gated Na+ channel.
Topics: Amino Acid Sequence; Amino Acid Substitution; Animals; Cell Line; Cysteine; DNA, Complementary; Female; FMRFamide; Humans; Ion Channel Gating; Ion Transport; Mesylates; Models, Molecular; Molecular Sequence Data; Multigene Family; Mutagenesis, Site-Directed; Oocytes; Protein Conformation; Protein Structure, Tertiary; Recombinant Fusion Proteins; Sequence Alignment; Sequence Homology, Amino Acid; Sodium; Sodium Channels; Static Electricity; Sulfhydryl Reagents; Xenopus laevis | 2001 |
Characterization of a glycine receptor domain that controls the binding and gating mechanisms of the beta-amino acid agonist, taurine.
Topics: Amino Acid Substitution; Binding Sites; Cell Line; Cysteine; Glycine; Humans; Ion Channel Gating; Kidney; Mesylates; Mutagenesis, Site-Directed; Protein Structure, Tertiary; Receptors, Glycine; Sulfhydryl Reagents; Taurine | 2001 |
The mitochondrial oxoglutarate carrier: cysteine-scanning mutagenesis of transmembrane domain IV and sensitivity of Cys mutants to sulfhydryl reagents.
Topics: Amino Acid Sequence; Amino Acid Substitution; Animals; Biological Transport, Active; Carrier Proteins; Cattle; Cysteine; Ethyl Methanesulfonate; Ethylmaleimide; Ketoglutaric Acids; Membrane Proteins; Membrane Transport Proteins; Mesylates; Mitochondria, Heart; Molecular Sequence Data; Mutagenesis, Site-Directed; Protein Structure, Secondary; Protein Structure, Tertiary; Proteolipids; Recombinant Proteins; Sulfhydryl Reagents | 2001 |
Cysteine mutagenesis and computer modeling of the S6 region of an intermediate conductance IKCa channel.
Topics: Animals; Computers; Cysteine; Electric Conductivity; Female; HeLa Cells; Humans; Mesylates; Models, Biological; Models, Genetic; Mutagenesis; Oocytes; Potassium Channels, Calcium-Activated; Sequence Homology; Sulfhydryl Reagents; Xenopus laevis | 2002 |
Site-directed mutagenesis and chemical modification of the six native cysteine residues of the rat mitochondrial carnitine carrier: implications for the role of cysteine-136.
Topics: Amino Acid Sequence; Amino Acid Substitution; Animals; Carrier Proteins; Cloning, Molecular; Cysteine; Escherichia coli; Ethyl Methanesulfonate; Ethylmaleimide; Mesylates; Mitochondria; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Organic Cation Transport Proteins; Protein Structure, Secondary; Rats; Recombinant Proteins; Solute Carrier Family 22 Member 5; Sulfhydryl Reagents | 2002 |
Complete replacement of basic amino acid residues with cysteines in Rickettsia prowazekii ATP/ADP translocase.
Topics: Amino Acids, Basic; Arginine; Cysteine; Cytoplasm; Kinetics; Lysine; Mesylates; Mitochondrial ADP, ATP Translocases; Mutagenesis, Site-Directed; Mutation; Periplasm; Protein Structure, Tertiary; Rickettsia prowazekii | 2002 |
Sodium (2-sulfonatoethyl) methanethiosulfonate prevents S-nitroso-L-cysteine activation of Ca2+-activated K+ (BKCa) channels in myocytes of the guinea-pig taenia caeca.
Topics: Animals; Cecum; Cysteine; Guinea Pigs; Membrane Potentials; Mesylates; Myocytes, Smooth Muscle; Potassium Channels, Calcium-Activated; S-Nitrosothiols | 2003 |
An investigation of cysteine mutants on the cytoplasmic loop X/XI in the melibiose transporter of Escherichia coli by using thiol reagents: implication of structural conservation of charged residues.
Topics: 4-Chloromercuribenzenesulfonate; Amino Acids; Animals; Biological Transport; Cells, Cultured; Cysteine; Escherichia coli Proteins; Iodoacetic Acid; Melibiose; Mesylates; Mutation; Protein Structure, Secondary; Sulfhydryl Reagents; Symporters | 2003 |
Structure and function of extracellular loop 4 of the serotonin transporter as revealed by cysteine-scanning mutagenesis.
Topics: Animals; Binding Sites; Biological Transport; Biotinylation; Carrier Proteins; Cocaine; Cysteine; DNA, Complementary; Dose-Response Relationship, Drug; HeLa Cells; Humans; Indicators and Reagents; Ions; Kinetics; Membrane Glycoproteins; Membrane Transport Proteins; Mesylates; Models, Molecular; Mutagenesis, Site-Directed; Mutation; Nerve Tissue Proteins; Protein Binding; Protein Conformation; Protein Structure, Tertiary; Protein Transport; Rats; Serotonin; Serotonin Plasma Membrane Transport Proteins; Structure-Activity Relationship; Zinc | 2004 |
Cysteine-scanning mutagenesis of the fifth external loop of serotonin transporter.
Topics: Alanine; Amino Acid Sequence; Animals; Binding Sites; Biological Transport; Carrier Proteins; Cocaine; Cysteine; Dose-Response Relationship, Drug; Epitopes; HeLa Cells; Humans; Ions; Membrane Glycoproteins; Membrane Transport Proteins; Mesylates; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; Nerve Tissue Proteins; Protein Structure, Secondary; Protein Structure, Tertiary; Rats; Sequence Homology, Amino Acid; Serotonin; Serotonin Plasma Membrane Transport Proteins; Sodium; Threonine | 2004 |
The drug-binding pocket of the human multidrug resistance P-glycoprotein is accessible to the aqueous medium.
Topics: Adenosine Triphosphatases; Adenosine Triphosphate; ATP Binding Cassette Transporter, Subfamily B, Member 1; Binding Sites; Biological Transport; Buffers; Cell Line; Colchicine; Cyclosporine; Cysteine; Drug Resistance, Multiple; Gene Expression Regulation; Humans; Hydrolysis; Isoleucine; Mesylates; Mutation; Rhodamines; Verapamil; Water | 2004 |
Cysteine modification alters voltage- and Ca(2+)-dependent gating of large conductance (BK) potassium channels.
Topics: Animals; Calcium; Cysteine; Electrophysiology; Humans; Indicators and Reagents; Ion Channel Gating; Large-Conductance Calcium-Activated Potassium Channel alpha Subunits; Large-Conductance Calcium-Activated Potassium Channels; Mesylates; Mice; Potassium Channels, Calcium-Activated | 2005 |
Cysteine accessibility in ClC-0 supports conservation of the ClC intracellular vestibule.
Topics: Algorithms; Amino Acid Sequence; Animals; Axons; Carrier Proteins; Chloride Channels; Cross-Linking Reagents; Cysteine; Disulfides; Indicators and Reagents; Ion Channel Gating; Membrane Potentials; Mesylates; Molecular Sequence Data; Mutagenesis; Mutagens; Oocytes; Patch-Clamp Techniques; Protein Conformation; Reverse Transcriptase Polymerase Chain Reaction; Stilbenes; Sulfonic Acids; Xenopus | 2005 |
Cysteine-scanning mutagenesis of serotonin transporter intracellular loop 2 suggests an alpha-helical conformation.
Topics: Amino Acid Sequence; Animals; Cysteine; Ethyl Methanesulfonate; HeLa Cells; Humans; Indicators and Reagents; Membrane Glycoproteins; Membrane Transport Proteins; Mesylates; Molecular Sequence Data; Mutagenesis; Nerve Tissue Proteins; Protein Structure, Secondary; Rats; Sequence Alignment; Serotonin; Serotonin Plasma Membrane Transport Proteins | 2005 |
Substituted cysteine accessibility of the third transmembrane domain of the creatine transporter: defining a transport pathway.
Topics: Amino Acid Sequence; Binding Sites; Biological Transport; Biotinylation; Cell Line; Cell Membrane; Chlorine; Creatine; Cysteine; Dose-Response Relationship, Drug; Humans; Ions; Membrane Transport Proteins; Mesylates; Models, Biological; Molecular Sequence Data; Mutagenesis; Mutation; Protein Binding; Protein Structure, Tertiary; Sodium; Solvents; Sulfhydryl Reagents; Time Factors; Transfection | 2005 |
Localization of a substrate binding domain of the human reduced folate carrier to transmembrane domain 11 by radioaffinity labeling and cysteine-substituted accessibility methods.
Topics: Amino Acid Sequence; Anions; Aspartic Acid; Blotting, Western; Cell Line; Cell Membrane; Cysteine; Cytosol; Folic Acid; Glutamine; HeLa Cells; Histidine; Humans; K562 Cells; Leucovorin; Membrane Transport Proteins; Mesylates; Microscopy, Fluorescence; Molecular Sequence Data; Mutagenesis; Mutation; Peptides; Protein Binding; Protein Conformation; Protein Structure, Secondary; Protein Structure, Tertiary; Reduced Folate Carrier Protein; Sulfhydryl Reagents; Temperature; Thiocyanates; Time Factors; Transfection; Tyrosine | 2005 |
State-dependent chemical reactivity of an engineered cysteine reveals conformational changes in the outer vestibule of the cystic fibrosis transmembrane conductance regulator.
Topics: Adenosine Triphosphate; Cysteine; Cystic Fibrosis Transmembrane Conductance Regulator; Ion Channel Gating; Kinetics; Mesylates; Mutagenesis, Site-Directed; Protein Conformation; Protein Engineering | 2005 |
Variable reactivity of an engineered cysteine at position 338 in cystic fibrosis transmembrane conductance regulator reflects different chemical states of the thiol.
Topics: Alkylating Agents; Animals; Catalysis; Copper; Cysteine; Cystic Fibrosis Transmembrane Conductance Regulator; Disulfides; Dithiothreitol; Glutathione; Humans; Hydrogen Peroxide; Hydrogen-Ion Concentration; Iodoacetamide; Mercaptoethanol; Mesylates; Metals; Models, Biological; Oocytes; Oxygen; Phenotype; Protein Engineering; Sulfhydryl Compounds; Sulfinic Acids; Sulfonic Acids; Time Factors; Xenopus | 2006 |
Site-directed alkylation of cysteine replacements in the lactose permease of Escherichia coli: helices I, III, VI, and XI.
Topics: Alkylation; Amino Acid Sequence; Cysteine; Escherichia coli Proteins; Ethylmaleimide; Liposomes; Mesylates; Monosaccharide Transport Proteins; Protein Structure, Secondary; Symporters | 2006 |
Measurement of conformational changes accompanying desensitization in an ionotropic glutamate receptor.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cell Line; Crystallography, X-Ray; Cysteine; Dimerization; Disulfides; Electrophysiology; Glutamic Acid; Humans; Mesylates; Models, Molecular; Molecular Sequence Data; Oocytes; Point Mutation; Protein Structure, Quaternary; Rats; Receptors, AMPA; Sulfhydryl Reagents; Xenopus laevis | 2006 |
Control of inward rectifier K channel activity by lipid tethering of cytoplasmic domains.
Topics: Bacterial Proteins; Burkholderia pseudomallei; Cell-Free System; Cloning, Molecular; Cysteine; Ethyl Methanesulfonate; Ion Channel Gating; Membrane Lipids; Mesylates; Methyl Methanesulfonate; Models, Molecular; Mutation; Potassium Channels, Inwardly Rectifying; Protein Binding; Protein Conformation; Protein Structure, Tertiary; Rubidium Radioisotopes; Sulfhydryl Reagents | 2007 |
KCNE1 and KCNE3 stabilize and/or slow voltage sensing S4 segment of KCNQ1 channel.
Topics: Animals; Binding Sites; Cysteine; Disulfides; Female; Humans; Ion Channel Gating; KCNQ1 Potassium Channel; Kinetics; Membrane Potentials; Mesylates; Mice; Models, Biological; Mutagenesis, Site-Directed; Oocytes; Potassium Channels, Voltage-Gated; Protein Binding; Protein Structure, Tertiary; Rats; Sulfhydryl Reagents; Xenopus | 2007 |
Conformation-dependent accessibility of Cys-136 and Cys-155 of the mitochondrial rat carnitine/acylcarnitine carrier to membrane-impermeable SH reagents.
Topics: Animals; Biological Transport; Carnitine; Carnitine Acyltransferases; Cysteine; Dose-Response Relationship, Drug; Ethyl Methanesulfonate; Fluoresceins; Membrane Transport Proteins; Mesylates; Mitochondria; Models, Molecular; Mutant Proteins; Mutation; Permeability; Protein Conformation; Rats; Substrate Specificity; Sulfhydryl Reagents | 2007 |
Cytosolic half of transmembrane domain IV of the human bile acid transporter hASBT (SLC10A2) forms part of the substrate translocation pathway.
Topics: Amino Acid Sequence; Animals; Chlorocebus aethiops; Computational Biology; COS Cells; Cysteine; Cytosol; Humans; Mesylates; Models, Molecular; Molecular Sequence Data; Organic Anion Transporters, Sodium-Dependent; Point Mutation; Protein Structure, Secondary; Protein Structure, Tertiary; Sequence Alignment; Symporters | 2008 |
Transmembrane IV of the high-affinity sodium-glucose cotransporter participates in sugar binding.
Topics: Alkylation; Animals; Carbohydrate Metabolism; Chlorocebus aethiops; COS Cells; Cricetinae; Cysteine; Ethyl Methanesulfonate; Female; Mesylates; Methylglucosides; Mutation, Missense; Oocytes; Patch-Clamp Techniques; Phlorhizin; Protein Structure, Tertiary; Rabbits; Sodium-Glucose Transporter 1; Xenopus laevis | 2008 |
Structural and functional characterization of transmembrane segment IX of the NHE1 isoform of the Na+/H+ exchanger.
Topics: Cation Transport Proteins; Cations; Cell Line, Tumor; Circular Dichroism; Cysteine; Gene Expression Regulation; Humans; Magnetic Resonance Spectroscopy; Mesylates; Micelles; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Peptides; Protein Isoforms; Protein Structure, Tertiary; Sodium-Hydrogen Exchanger 1; Sodium-Hydrogen Exchangers; Sulfhydryl Reagents | 2008 |
Novel residues lining the CFTR chloride channel pore identified by functional modification of introduced cysteines.
Topics: Amino Acid Sequence; Animals; Cricetinae; Cysteine; Cystic Fibrosis Transmembrane Conductance Regulator; Humans; Mesylates; Mutagenesis, Site-Directed; Patch-Clamp Techniques; Sulfhydryl Reagents | 2009 |
Identification of transmembrane domain 6 & 7 residues that contribute to the binding pocket of the urotensin II receptor.
Topics: Alkylating Agents; Animals; Chlorocebus aethiops; COS Cells; Cysteine; Ethyl Methanesulfonate; Ligands; Mesylates; Models, Molecular; Mutation; Polymerase Chain Reaction; Protein Binding; Protein Structure, Tertiary; Radioligand Assay; Rats; Receptors, G-Protein-Coupled; Transfection; Urotensins | 2009 |
Cysteine-independent inhibition of the CFTR chloride channel by the cysteine-reactive reagent sodium (2-sulphonatoethyl) methanethiosulphonate.
Topics: Animals; Cell Line; Cricetinae; Cysteine; Cystic Fibrosis Transmembrane Conductance Regulator; Humans; Mesylates; Sulfhydryl Reagents | 2009 |
Transmembrane segment II of NhaA Na+/H+ antiporter lines the cation passage, and Asp65 is critical for pH activation of the antiporter.
Topics: Aspartic Acid; Cations; Cell Membrane; Computer Simulation; Conserved Sequence; Crystallography, X-Ray; Cysteine; Escherichia coli; Escherichia coli Proteins; Gene Expression Regulation, Bacterial; Hydrogen-Ion Concentration; Ion Transport; Lithium; Mesylates; Models, Molecular; Mutation; Periplasm; Phenotype; Protein Conformation; Sodium-Hydrogen Exchangers | 2010 |
State-dependent electrostatic interactions of S4 arginines with E1 in S2 during Kv7.1 activation.
Topics: Amino Acid Sequence; Animals; Arginine; Cell Membrane; Cysteine; Ion Channel Gating; KCNQ1 Potassium Channel; Long QT Syndrome; Membrane Potentials; Mesylates; Models, Molecular; Molecular Sequence Data; Mutation; Protein Conformation; Protein Structure, Tertiary; Protein Transport; Sulfhydryl Reagents; Surface Properties; Time Factors; Xenopus | 2010 |
Differentially altered Ca2+ regulation and Ca2+ permeability in Cx26 hemichannels formed by the A40V and G45E mutations that cause keratitis ichthyosis deafness syndrome.
Topics: Amino Acid Substitution; Animals; Barium; Calcium; Cell Line, Tumor; Chelating Agents; Chloride Channels; Connexin 26; Connexins; Cysteine; Deafness; Electrophysiological Phenomena; Ethylenediamines; Gap Junctions; Humans; Ion Channel Gating; Keratitis; Membrane Potentials; Mesylates; Mice; Mutation, Missense; Oocytes; Permeability; RNA, Messenger; Streptomyces; Sulfhydryl Reagents; Syndrome; Transfection; Xenopus laevis | 2010 |
Structural and functional analysis of transmembrane segment VI of the NHE1 isoform of the Na+/H+ exchanger.
Topics: Cation Transport Proteins; Cell Membrane; Cysteine; Humans; Immunoblotting; Magnetic Resonance Spectroscopy; Mesylates; Mutagenesis, Site-Directed; Mutation; Protein Conformation; Protein Isoforms; Sodium-Hydrogen Exchanger 1; Sodium-Hydrogen Exchangers; Structure-Activity Relationship | 2010 |
Electrostatic charge at position 552 affects the activation and permeation of FMRFamide-gated Na+ channels.
Topics: Animals; Aplysia; Cysteine; Dose-Response Relationship, Drug; FMRFamide; Ion Channel Gating; Membrane Potentials; Mesylates; Models, Molecular; Mutation; Nerve Tissue Proteins; Oocytes; Permeability; Protein Conformation; Sodium; Sodium Channels; Static Electricity; Surface Properties; Xenopus laevis | 2014 |
The Fifth Transmembrane Segment of Cystic Fibrosis Transmembrane Conductance Regulator Contributes to Its Anion Permeation Pathway.
Topics: Amino Acid Substitution; Animals; Cell Membrane Permeability; CHO Cells; Cricetulus; Cysteine; Cystic Fibrosis Transmembrane Conductance Regulator; Humans; Mesylates; Models, Molecular; Mutant Proteins; Patch-Clamp Techniques; Peptide Fragments; Protein Conformation; Protein Engineering; Protein Structure, Tertiary; Recombinant Proteins; Sulfhydryl Reagents; Surface Properties | 2015 |
Cysteine Substitution and Labeling Provide Insight into Channelrhodopsin-2 Ion Conductance.
Topics: Animals; Chlamydomonas reinhardtii; Cysteine; Electricity; Female; Indicators and Reagents; Ion Channel Gating; Kinetics; Light; Mesylates; Models, Molecular; Mutagenesis, Site-Directed; Oocytes; Patch-Clamp Techniques; Permeability; Protein Structure, Tertiary; Rhodopsin; Xenopus laevis | 2015 |