Page last updated: 2024-08-17

cysteamine and metyrapone

cysteamine has been researched along with metyrapone in 9 studies

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19905 (55.56)18.7374
1990's1 (11.11)18.2507
2000's1 (11.11)29.6817
2010's2 (22.22)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Flemming, K; Gertz, J; Hinkelbein, W; Mull, R1
Beckett, AH; Gorrod, JW; Temple, DJ1
Fandrey, J; Jelkmann, W; Seydel, FP; Siegers, CP1
Franklin, MR1
Flemming, K; Gertz, J; Mull, RH1
Flemming, K; Seydewitz, V1

Reviews

1 review(s) available for cysteamine and metyrapone

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Other Studies

8 other study(ies) available for cysteamine and metyrapone

ArticleYear
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models.
    Toxicology mechanisms and methods, 2008, Volume: 18, Issue:2-3

    Topics:

2008
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship

2012
A comparative study on the influence of cysteamine and metyrapone on mixed-function oxygenase activities in variously pretreated liver microsomes from rats and mice.
    Biochimica et biophysica acta, 1977, Apr-12, Volume: 481, Issue:2

    Topics: Acetanilides; Animals; Cysteamine; Disulfides; Kinetics; Magnesium; Methylcholanthrene; Metyrapone; Mice; Microsomes, Liver; Mixed Function Oxygenases; Niacinamide; Nitroanisole O-Demethylase; Oxidoreductases; Phenobarbital; Rats; Time Factors

1977
The differentiation of N-oxidation and N-dealkylation of N-ethyl-N-methylaniline by rabbit liver microsomes as distinct metabolic routes.
    Xenobiotica; the fate of foreign compounds in biological systems, 1975, Volume: 5, Issue:8

    Topics: 2,2'-Dipyridyl; Acetone; Aniline Compounds; Animals; Chloromercuribenzoates; Cysteamine; Cytochrome P-450 Enzyme System; Dealkylation; Dithiothreitol; Ethylmaleimide; Kinetics; Liver; Male; Metyrapone; Microsomes, Liver; NADP; Oxidoreductases; Proadifen; Rats; Subcellular Fractions

1975
Role of cytochrome P450 in the control of the production of erythropoietin.
    Life sciences, 1990, Volume: 47, Issue:2

    Topics: Carcinoma, Hepatocellular; Cobalt; Cysteamine; Cytochrome P-450 Enzyme System; Ditiocarb; Erythropoietin; Humans; Liver Neoplasms; Methylcholanthrene; Metyrapone; Microsomes; Oxygen; Phenobarbital; Thyroxine; Triiodothyronine; Tumor Cells, Cultured

1990
Piperonyl butoxide metabolism by cytochrome P-450: factors affecting the formation and disappearance of the metabolite-cytochrome P-450 complex.
    Xenobiotica; the fate of foreign compounds in biological systems, 1972, Volume: 2, Issue:6

    Topics: Animals; Cysteamine; Cytochrome P-450 Enzyme System; Dioxoles; Glucuronates; Hexobarbital; Kinetics; Male; Metyrapone; Mice; Microsomes, Liver; NAD; NADP; Oxidation-Reduction; Pesticide Synergists; Piperonyl Butoxide; Protein Binding; Rats; S-Adenosylmethionine; Spectrophotometry; Uridine Diphosphate Sugars

1972
Proceedings: The effect of cysteamine on the microsomal drug metabolism system.
    Naunyn-Schmiedeberg's archives of pharmacology, 1974, Volume: 282, Issue:Suppl

    Topics: Acetanilides; Animals; Biotransformation; Cysteamine; Dealkylation; In Vitro Techniques; Kinetics; Methylcholanthrene; Metyrapone; Mice; Microsomes, Liver; Mixed Function Oxygenases; Peroxidases; Pharmaceutical Preparations; Phenobarbital

1974
A study of the inhibition by cysteamine on the steroid 11 beta-hydroxylation.
    Experientia, 1974, Sep-15, Volume: 30, Issue:9

    Topics: Adrenal Cortex; Adrenal Glands; Animals; Corticosterone; Cysteamine; Desoxycorticosterone; Hydroxylation; Metyrapone; Rats; Steroid Hydroxylases; Structure-Activity Relationship

1974