Page last updated: 2024-08-17

cysteamine and cystamine

cysteamine has been researched along with cystamine in 190 studies

Research

Studies (190)

TimeframeStudies, this research(%)All Research%
pre-1990143 (75.26)18.7374
1990's19 (10.00)18.2507
2000's13 (6.84)29.6817
2010's13 (6.84)24.3611
2020's2 (1.05)2.80

Authors

AuthorsStudies
De Guzman, RN; McDonnell, NB; Rice, WG; Summers, MF; Turpin, JA1
Schleicher, E; Simon, H1
Griffith, OW; Larsson, A; Meister, A1
Balny, C; Bonfils, C; Debey, P1
Crawhall, JC; Oshima, RG; Schneider, JA; Thoene, JG1
Knowles, CL; Lyman, EM; Sribney, M1
Budke, L; Grant, GA; Vos, O2
Messerschmidt, O1
Apffel, CA; Issarescu, S; Walker, JE1
Flemming, K1
Bitny-Szlachto, S; Sołtysiak-Pawluczuk, D1
Lushnikova, GA1
Crawhall, JC; Olson, DL; Oshima, RG; Schneider, JA; Thoene, JG1
Master, BS; Roeder, SB; Stewart, CJ1
Haren, J; Mewissen, DJ; Rust, JH1
Bollinger-Gruber, JA; Brown, A; Reichlin, S; Szabo, S1
Baase, WA; Dahlquist, FW; Lu, J; Muchmore, DC1
Choughuley, AS; Shenoy, NR1
Ganther, HE; Ip, C1
Djurhuus, R; Mansoor, MA; Svardal, AM; Ueland, PM1
Jeitner, TM; Oliver, JR1
Sperk, G; Widmann, R1
Maas, D; Sperk, G; Widmann, R1
Fatome, M; Imbach, JL; Oiry, J; Pue, JY; Sentenac-Roumanou, H1
Cohen, GM; Haschek, WM; Lewis, CP; Smith, LL; Wyatt, I1
Costa, T; Kodama, H; Kondo, M; Shimohigashi, Y1
Fatome, M; Imbach, JL; Lion, C; Oiry, J; Pue, JY; Sentenac-Roumanou, H1
Di Cola, D; Sacchetta, P1
Lakin, CA; Oliver, JR; Scott, JS1
Hengartner, H; Schott, H; Schwendener, RA; Seeling, R1
Duffel, MW; Logan, DJ; Ziegler, DM1
Toohey, JI1
Cappel, RE; Gilbert, HF1
Butler, JD; Gahl, WA; Schulman, JD; Tietze, F1
Gandolfi, AJ; MacDonald, JR; Sipes, IG2
Bacq, ZM; Lecomte, J1
Bacq, ZM; Beaumariage, ML; van Caneghem, P2
Ababei, L; Serban, F1
Skrede, S1
Duchesne, PY; Hajdukovic, S1
Freyland, W; Müller, A1
Dertinger, H; Nicolau, C1
Castro, JA; D'Acosta, N; De Castro, CR; De Fenos, OM; De Ferreyra, EC; Díaz Gómez, MI1
Hotz, G1
Chiba, M; Eto, K; Tsuruta, M1
Okada, S; Roots, R1
Baev, I; Bairakova, A; Benova, D2
Ivanov, II; Vertushkov, VT1
Beaumariage, ML; van Caneghem, P1
Kuna, P1
Carr, CJ; Fisher, KD; Huber, TE; Huff, JE1
Saxena, VP; Wetlaufer, DB1
Panek, R1
Ormerod, MG; Stevens, U1
Vergroesen, AJ; Vos, O; Zwenk, H1
Dunjic, A1
Bacon, VA; Halpern, B; Jellum, E; Patton, W; Pereira, W1
Briedis, I; Goncharenko, EN; Kudriashov, IuB1
Del Grosso, E; Duprè, S; Fabi, A; Graziani, MT; Rosei, MA1
Okada, S; Sawada, S1
Kuznetsov, VI; Tank, LI; Zil'ber, IuD1
Bacq, ZM; Beaumariage, ML; Duchesne, PY; Hajduković, S1
Bacq, ZM; Beaumariage, ML; Goutier, R; Van Caneghem, P1
Ueno, Y1
Markoe, AM; Tannard, JN1
Van de Vijver, G1
Van Caneghem, P1
Dzharak'ian, TK; Golubentsev, DA; Vladimirov, VG1
Cavallini, D; Scandurra, R1
Frölén, H1
Christophersen, BO; Skrede, S1
Graevskiĭ, EIa; Nekrasova, IV; Tarasenko, AG1
Friedman, OM; Herrington, KA; Meister, A; Pointer, K1
Dunn, JA; Greenberg, RN; Guerrant, RL1
Belleau, B; Benfey, BG; Brasili, L; Melchiorre, C1
Ganguly, SK; Ghose, A; Kaur, J1
Ida, S; Kuriyama, K; Ohkuma, S; Tanaka, Y1
Hosek, B; Kautská, J; Misustová, J1
Armour, EP; Corry, PM1
Cutilli, JR; Douglas, SD; Ho, WZ; Lee, HR; Song, L; Zhu, XH1
Holmgren, A; Lundström-Ljung, J1
Gräf, M; Kalinowski, HO1
Terada, T1
Birnbach, U; Lundström, J; Rupp, K; Söling, HD; Van, PN1
Imamura, Y; Kataoka, H; Makita, M; Tanaka, H1
Camici, M; Cappiello, M; Del Corso, A; Mura, U1
De Marco, C; Floris, G; Lorrai, A; Medda, R; Padiglia, A1
Chang, D; Jimbow, K; Samra, S; Shokravi, M; Singh, S; Tandon, M; Thomas, PD1
Misík, V; Miyoshi, N; Riesz, P1
Jimbow, K; Minamitsuji, Y; Sugiyama, S; Toyofuku, K; Yamada, K1
Cao, H; Jimbow, K; Kishi, H; Ota, M; Singh, S; Thomas, PD; Yamashita, T1
Mukhopadhyay, A1
Gili, A; Jimbow, K; Ota, M; Thomas, PD1
Hsiung, KP; Liu, YC; Wang, CM1
FISCHER, P; GOUTIER-PIROTTE, M1
DELLA BELLA, D; GOFFART, M1
ELDJARN, L; NYGAARD, O2
ELDJARN, L1
LECOMTE, J1
ELDJARN, L; SHAPIRO, B1
DEVIK, F; LOTHE, F1
KOCH, R1
GOFFART, M1
BALDINI, G; FERRI, L4
ELDJARN, L; PIHL, A1
BRUCER, M; MEWISSEN, DJ1
RUGH, R1
BETZ, EH; BOOZ, G3
MORGAN, JF; MORTON, HJ1
BOOZ, G1
EKER, R; OFTEBRO, R; OFTEDAL, P1
BETZ, EH; BOOZ, G; LELIEVRE, P1
VASIL'EV, GA1
MEWISSEN, DJ1
GOFFART, M; GREVISSE, J1
COLETTA, M; DE MARCO, C1
LELIEVRE, P3
VAN DE BERG, A1
HEIFFER, MH; MEHLMAN, B; MUNDY, RL1
THERKELSEN, AJ1
FIRKET, H; LELIEVRE, P; SMOLIAR, V2
CESSION-FOSSION, A; LECOMTE, J; LIBON, JC1
HAOT, J1
HENRIKSEN, T; PIHL, A; SANNER, T1
BUDKE, L; VERGROESEN, AJ; VOS, O1
KOCH, R; LANGENDORFF, M1
NAKKEN, KF1
BONKER, GJ; TONGE, BL1
STROEMME, JH1
SMOLIAR, V1
IARMONENKO, SP1
CONTRACTOR, SF1
BOCCACCI, M; QUINTILIANI, M1
IARMONENKO, SP; IVANOV, VN1
SHAMAKHMUDOV, A1
BACQ, ZM; LIEBECQ, C; THOMOU, A1
EKER, P; PIHL, A1
SHAPIRO, B1
KUZNETSOV, VI; TANK, LI1
BOCCACCI, M; MISITIDORELLO, P; QUINTILIANI, M1
BACQ, ZM; CESSION-FOSSION, A; LECOMTE, J; LIBON, JC1
ALEXANDER, P; BACQ, ZM1
COUVREUR, P; DUNJIC, A; MAISIN, J1
BETZ, EH; HAOT, J1
RALL, JE; WOLFF, J1
BACQ, ZM; BEAUMARIAGE, ML1
ELDJARN, L; JELLUM, E1
BOMBARDIERI, G; CAVALLINI, D; DEMARCO, C; DUPRE, S; RIVA, F1
BACQ, ZM; BEAUMARIAGE, ML; LIEBECQ HUTTER, S1
FRIART, J1
HERVE, A1
FIORI, GP; GORINI, P; RONDANELLI, EG; TRENTA, A1
Berruyer, C; Castellano, R; Duprè, S; Galland, F; Garrido-Urbani, S; Imbert, J; Macone, A; Malergue, F; Martin, FM; Millet, V; Naquet, P; Pitari, G1
Cho, SY; Jang, GY; Jeon, JH; Kim, CW; Kim, IG; Lee, HJ; Park, SC; Shim, DM; Yeo, EJ1
Cooper, AJ; Hayden, MR; Jeitner, TM; Krasnikov, BF; Leavitt, BR; Pinto, JT; Thaler, HT; Van Raamsdonk, JM1
Alberch, J; Borrell-Pagès, M; Brouillet, E; Bryson, EA; Canals, JM; Cheetham, ME; Cordelières, FP; Grange, G; Guillermier, M; Hantraye, P; Hirsch, E; Humbert, S; Néri, C; Parker, JA; Pineda, JR; Saudou, F1
Choo, YS; Lesort, M; Mao, Z1
Frankish, H1
Fujii, T; Ohkuri, T; Onodera, R; Ueda, T1
Beger, RD; Holland, RD; Koza-Taylor, PH; Lawton, MP; Manautou, JE; Moffit, JS; Thibodeau, MS1
Berbeci, LS; Kaifer, AE; Wang, W1
Cooper, AJ; Denton, TT; Jeitner, TM; Khomenko, T; Krasnikov, BF; McLaren, GD; Pinto, JT; Szabo, S1
Bousquet, M; Calon, F; Cicchetti, F; Gibrat, C; Ouellet, M; Rouillard, C1
Koppenol, WH; Nauser, T; Steinmann, D1
Cicchetti, F; Gibrat, C1
Chen, L; Cooper, AJ; Deng, X; Hoa, N; Khomenko, T; Kolodney, J; Krasnikov, BF; McLaren, GD; Paunovic, B; Pinto, JT; Szabo, S; Tolstanova, G1
Adams, E; Carvalho, AZ; D'Autry, W; da Silva, JA; El-Attug, MN; Hoogmartens, J; Van Schepdael, A; Wolfs, K1
Benylles, A; Cairns, D; Cox, PJ; Kay, G1
Bona, G; Bossi, A; De Gregorio, F; De Rosa, G; De Stefano, D; Esposito, S; Grassia, R; Guido, S; Kroemer, G; Leone, CA; Maiuri, L; Maiuri, MC; Mehta, A; Pettoello-Mantovani, M; Pinna, LA; Raia, V; Salvadori, L; Sepe, A; Tosco, A; Venerando, A; Villella, VR; Zolin, A1
Bebawy, M; Luk, F; Roseblade, A; Ung, A1
Badrinarayanan, S; Boivin, L; Bousquet, M; Chabrat, A; Charest, J; Cicchetti, F; Cisbani, G; Drouin-Ouellet, J; Gibrat, C; Lagacé, M; Lavallée-Bourget, MH; Lebel, M; Lévesque, M; Saint-Pierre, M1
Cole, M; Doumith, M; Fraser-Pitt, DJ; Hill, RLR; Hopkins, KL; Kowalczuk, A; Lovie, E; Mercer, DK; O'Neil, DA; Perenyi, P; Robertson, J; Smith, D; Woodford, N1
Cooper, AJL; Jeitner, TM; Pinto, JT1
Deng, N; Deng, Z; He, J; Jin, B; Li, Y; Song, L; Wang, B; Wu, X1
De Maio, F; De Spirito, M; Delogu, G; Fimia, GM; Goletti, D; Maulucci, G; Palucci, I; Petrone, L; Piacentini, M; Romagnoli, A; Sali, M; Sanguinetti, M1
Aiello, A; Alonzi, T; Capobianchi, MR; Castilletti, C; D'Eletto, M; Delogu, G; Falasca, L; Goletti, D; Ippolito, G; Najafi Fard, S; Nardacci, R; Petrone, L; Piacentini, M; Rossin, F1
D'Eletto, M; De Maio, F; Delogu, G; Goletti, D; Occhigrossi, L; Paglione, F; Palucci, I; Pereyra Boza, MDC; Piacentini, M; Rossin, F; Sali, M; Salustri, A; Sanguinetti, M1

Reviews

7 review(s) available for cysteamine and cystamine

ArticleYear
Cystine depletion of cystinotic cells by aminothiols.
    Proceedings of the Royal Society of Medicine, 1977, Volume: 70 Suppl 3

    Topics: Cell-Free System; Cystamine; Cysteamine; Cysteine; Cystinosis; Fibroblasts; Humans; Penicillamine; Sulfhydryl Compounds

1977
Some ideas concerning the mode of action of radioprotective agents.
    Experientia. Supplementum, 1977, Volume: 27

    Topics: Adrenal Glands; Animals; Corticosterone; Cystamine; Cysteamine; Desoxycorticosterone; Ethanolamines; Liver; Male; Mercaptoethanol; Mononuclear Phagocyte System; Oxidoreductases, O-Demethylating; Phagocytosis; Pituitary-Adrenal System; Radiation-Protective Agents; Rats; Steroid Hydroxylases

1977
[Pharmacological effects of radiation-protective agents cysteamine, cystamine, and aminoethylisothiuronium].
    Casopis lekaru ceskych, 1969, Volume: 108, Issue:13

    Topics: Animals; beta-Aminoethyl Isothiourea; Cystamine; Cysteamine; Mice; Rabbits; Radiation-Protective Agents

1969
Protective agents modifying biological effects of radiation. A selective review.
    Archives of environmental health, 1970, Volume: 21, Issue:1

    Topics: Animals; Behavior, Animal; beta-Aminoethyl Isothiourea; Blood Cells; Chromosome Aberrations; Cystamine; Cysteamine; Cysteine; Glutathione; Guanidines; Phosphoric Acids; Propiophenones; Radiation Effects; Radiation Injuries; Radiation Protection; Radiation-Protective Agents; Serotonin

1970
RESEARCH IN AGENTS TO PROTECT AGAINST IONIZING RADIATION.
    The Medical clinics of North America, 1964, Volume: 48

    Topics: Amines; Cyanides; Cystamine; Cysteamine; Cysteine; Humans; Pharmacology; Radiation Protection; Radiation-Protective Agents; Radiation, Ionizing; Research; Sulfur; Toxicology

1964
Potential of cystamine and cysteamine in the treatment of neurodegenerative diseases.
    Progress in neuro-psychopharmacology & biological psychiatry, 2011, Mar-30, Volume: 35, Issue:2

    Topics: Animals; Cystamine; Cysteamine; Disease Models, Animal; Enzyme Inhibitors; Humans; Huntington Disease; Mice; Mice, Transgenic; Molecular Targeted Therapy; Neurodegenerative Diseases; Neuroprotective Agents; Parkinson Disease; Radiation-Protective Agents

2011
Cystamine and cysteamine as inhibitors of transglutaminase activity
    Bioscience reports, 2018, 10-31, Volume: 38, Issue:5

    Topics: Biomarkers; Cystamine; Cysteamine; Cysteine; Enzyme Inhibitors; Humans; Oxidation-Reduction; Transglutaminases

2018

Trials

1 trial(s) available for cysteamine and cystamine

ArticleYear
Restoration of CFTR function in patients with cystic fibrosis carrying the F508del-CFTR mutation.
    Autophagy, 2014, Volume: 10, Issue:11

    Topics: Adaptor Proteins, Signal Transducing; Administration, Oral; Adolescent; Adult; Animals; Apoptosis Regulatory Proteins; Beclin-1; Catechin; Cell Membrane; Child; Chlorides; Cystamine; Cysteamine; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Female; Homozygote; Humans; Interleukin-8; Male; Membrane Proteins; Mice; Mice, Inbred CFTR; Mice, Transgenic; Mutation; Phenotype; Pilot Projects; Sequestosome-1 Protein; Tumor Necrosis Factor-alpha; Young Adult

2014

Other Studies

182 other study(ies) available for cysteamine and cystamine

ArticleYear
Zinc ejection as a new rationale for the use of cystamine and related disulfide-containing antiviral agents in the treatment of AIDS.
    Journal of medicinal chemistry, 1997, Jun-20, Volume: 40, Issue:13

    Topics: Acquired Immunodeficiency Syndrome; Amino Acid Sequence; Anti-HIV Agents; Capsid; Capsid Proteins; Cells, Cultured; Cystamine; Disulfiram; Ditiocarb; gag Gene Products, Human Immunodeficiency Virus; Gene Products, gag; Humans; Magnetic Resonance Spectroscopy; Molecular Sequence Data; Thiamine; Viral Proteins; Zinc Fingers

1997
On the mechanism and some properties of vinylacetyl-CoA delta-isomerase of Clostridium kluyveri.
    Hoppe-Seyler's Zeitschrift fur physiologische Chemie, 1976, Volume: 357, Issue:4

    Topics: Clostridium; Coenzyme A; Crotonates; Cystamine; Cysteamine; Hydrogen; Hydrogen-Ion Concentration; Isomerases

1976
Inhibition of gamma-glutamylcysteine synthetase by cystamine: an approach to a therapy of 5-oxoprolinuria (pyroglutamic aciduria).
    Biochemical and biophysical research communications, 1977, Dec-07, Volume: 79, Issue:3

    Topics: Amino Acid Metabolism, Inborn Errors; Animals; Brain; Cystamine; Cysteamine; Disulfides; gamma-Glutamylcyclotransferase; Glutamate-Cysteine Ligase; Glutamates; Humans; Kidney; Kinetics; Peptide Synthases; Rats; Sheep; Structure-Activity Relationship

1977
Biochemical effects on radioprotective agents on the liver microsomal hydroxylating system: in vitro studies.
    International journal of radiation biology and related studies in physics, chemistry, and medicine, 1978, Volume: 33, Issue:6

    Topics: Animals; Codeine; Cystamine; Cysteamine; Cytochrome P-450 Enzyme System; Cytochrome Reductases; Cytochromes; Hydroxylation; Lipid Metabolism; Microsomes, Liver; NADPH-Ferrihemoprotein Reductase; Rats

1978
Regulation of phosphatidylcholine synthesis in rat liver endoplasmic reticulum.
    The Biochemical journal, 1976, Jun-15, Volume: 156, Issue:3

    Topics: Acetyl Coenzyme A; Adenosine Triphosphate; Animals; Coenzyme A; Cystamine; Cysteamine; Diacylglycerol Cholinephosphotransferase; Endoplasmic Reticulum; Liver; Manganese; Nucleotides; Pantetheine; Pantothenic Acid; Phosphatidylcholines; Rats

1976
In vitro evaluation of some latent radioprotective compounds.
    International journal of radiation biology and related studies in physics, chemistry, and medicine, 1976, Volume: 30, Issue:5

    Topics: Amifostine; Animals; Blood; Cell Line; Cell Survival; Culture Media; Cystamine; Cysteamine; Dose-Response Relationship, Drug; Dose-Response Relationship, Radiation; Female; Hydrolysis; In Vitro Techniques; Mercaptoethylamines; Mice; Organothiophosphorus Compounds; Radiation-Protective Agents; Rats; X-Rays

1976
[Chemical radiation-protective agents (current status of research, application possibilities and their limitations].
    Strahlenschutz in Forschung und Praxis, 1977, Volume: 17

    Topics: Amifostine; Amphetamine; Chlorotrianisene; Cyanides; Cystamine; Cysteamine; Glucose; Pyridoxine; Radiation Dosage; Radiation-Protective Agents; Research; Thiourea; Tryptamines

1977
Tumor rejection in experimental animals treated with radioprotective thiols.
    Cancer research, 1975, Volume: 35, Issue:2

    Topics: Animals; beta-Aminoethyl Isothiourea; Carcinoma, Krebs 2; Cystamine; Cysteamine; Cysteine; Diamines; Dimethyl Sulfoxide; Drug Therapy, Combination; Glutathione; Graft Rejection; Guanidines; Mice; Mice, Inbred A; Mice, Inbred C3H; Mice, Inbred C57BL; Neoplasm Transplantation; Neoplasms, Experimental; Organothiophosphorus Compounds; Propylamines; Radiation-Protective Agents; Reserpine; Sarcoma, Experimental; Serotonin; Sulfhydryl Compounds; Transplantation, Homologous

1975
Activation of spleen adenylate cyclase by agents forming mixed disulfides.
    FEBS letters, 1978, Dec-01, Volume: 96, Issue:1

    Topics: Adenylyl Cyclases; Animals; Cystamine; Cysteamine; Disulfides; Enzyme Activation; Male; Mice; Spleen

1978
[Toxicity and side effects of antibiotics in radiation sickness and during the use of aminothiol group radioprotective agents].
    Antibiotiki, 1977, Volume: 22, Issue:9

    Topics: Animals; Anti-Bacterial Agents; Cystamine; Cysteamine; Dose-Response Relationship, Drug; Dose-Response Relationship, Radiation; Drug Interactions; Drug Tolerance; Gamma Rays; Lethal Dose 50; Mice; Rabbits; Radiation Injuries, Experimental; Radiation-Protective Agents; Rats; Time Factors

1977
Cystinosis. Intracellular cystine depletion by aminothiols in vitro and in vivo.
    The Journal of clinical investigation, 1976, Volume: 58, Issue:1

    Topics: Child; Cystamine; Cysteamine; Cystine; Cystinosis; Female; Fibroblasts; Glutathione; Humans; Leukocytes; Models, Biological; Oxidation-Reduction

1976
Influence of rat blood on radiation protection of mammalian cells by cysteamine and cystamine in vitro.
    International journal of radiation biology and related studies in physics, chemistry, and medicine, 1975, Volume: 28, Issue:1

    Topics: Animals; Blood; Cell Survival; Cells, Cultured; Cystamine; Cysteamine; Dose-Response Relationship, Drug; Dose-Response Relationship, Radiation; Radiation Effects; Radiation-Protective Agents; Rats; X-Rays

1975
13C NMR or coenzyme A and its constituent moieties.
    Physiological chemistry and physics, 1975, Volume: 7, Issue:2

    Topics: Adenosine Diphosphate; Alanine; Carbon Isotopes; Coenzyme A; Cystamine; Cysteamine; Deuterium; Disulfides; Lactones; Magnetic Resonance Spectroscopy; Mercaptoethylamines; Pantetheine; Pantothenic Acid; Protein Conformation

1975
Proceedings: Influence of cysteamine or cystamine on radiation late effects in C57BL/6 mice.
    British journal of cancer, 1975, Volume: 32, Issue:6

    Topics: Animals; Cystamine; Cysteamine; Mice; Mice, Inbred C57BL; Neoplasms, Experimental; Radiation Effects

1975
Somatostatin depleting potency of cysteamine-related thiols and amines in the rat: structure-activity relation.
    The Journal of pharmacology and experimental therapeutics, 1992, Volume: 263, Issue:2

    Topics: Amines; Aniline Compounds; Animals; Cystamine; Cysteamine; Down-Regulation; Ethylamines; Female; Gastric Mucosa; Propylamines; Rats; Rats, Sprague-Dawley; Somatostatin; Structure-Activity Relationship; Sulfhydryl Compounds

1992
Protein folding: assignment of the energetic changes of reversible chemical modifications to the folded or unfolded states.
    Biochemistry, 1992, Sep-01, Volume: 31, Issue:34

    Topics: Buffers; Circular Dichroism; Cystamine; Cysteamine; Enzyme Stability; Hot Temperature; Muramidase; Oxidation-Reduction; Protein Conformation; Protein Denaturation; Sulfhydryl Compounds; T-Phages; Thermodynamics

1992
Inhibitory effect of diet related sulphydryl compounds on the formation of carcinogenic nitrosamines.
    Cancer letters, 1992, Aug-31, Volume: 65, Issue:3

    Topics: Allium; Anticarcinogenic Agents; Chromatography, Gas; Cystamine; Cysteamine; Cysteic Acid; Cysteine; Cystine; Diet; Garlic; Glutathione; Humans; Morpholines; Nitrosamines; Nitrosation; Piperidines; Plants, Medicinal; Pyrrolidines; Sulfhydryl Compounds; Thioglycolates

1992
Comparison of selenium and sulfur analogs in cancer prevention.
    Carcinogenesis, 1992, Volume: 13, Issue:7

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antineoplastic Agents; Betaine; Cystamine; Cysteamine; Cysteine; Diet; Female; Mammary Neoplasms, Experimental; Organoselenium Compounds; Rats; Rats, Inbred Strains; Selenocysteine

1992
Modulation of glutathione content and the effect on methionine auxotrophy and cellular distribution of homocysteine and cysteine in mouse cell lines.
    Carcinogenesis, 1991, Volume: 12, Issue:2

    Topics: Animals; Antimetabolites; Buthionine Sulfoximine; Cell Division; Cell Line; Culture Media; Cystamine; Cysteamine; Cysteine; Fibroblasts; Glutathione; Homocysteine; Intracellular Fluid; Leukemia, Experimental; Methionine; Methionine Sulfoximine; Mice

1991
Effect of cysteamine on the lysosomal enzymes of the hyperprolactinaemic rat pituitary.
    The Journal of endocrinology, 1990, Volume: 125, Issue:1

    Topics: Animals; beta-Galactosidase; Cystamine; Cysteamine; Hyperprolactinemia; Lysosomes; Male; Pituitary Gland; Prolactin; Rats; Rats, Inbred Strains

1990
Cysteamine-induced decrease of somatostatin in rat brain synaptosomes in vitro.
    Endocrinology, 1987, Volume: 121, Issue:4

    Topics: Animals; Brain; Cystamine; Cysteamine; Hypothalamus; In Vitro Techniques; Isotonic Solutions; Male; Oxidation-Reduction; Rats; Somatostatin; Synaptosomes

1987
Effect of local injection of cysteamine and cystamine on somatostatin and neuropeptide Y levels in the rat striatum.
    Journal of neurochemistry, 1988, Volume: 50, Issue:6

    Topics: Animals; Chromatography, High Pressure Liquid; Corpus Striatum; Cystamine; Cysteamine; Male; Molecular Weight; Neuropeptide Y; Peptides; Rats; Rats, Inbred Strains; Somatostatin; Somatostatin-28

1988
Synthesis and radioprotective activity of dipeptide cysteamine and cystamine derivatives.
    Journal of medicinal chemistry, 1989, Volume: 32, Issue:2

    Topics: Animals; Cystamine; Cysteamine; Dipeptides; Mice; Radiation-Protective Agents

1989
The accumulation of cystamine and its metabolism to taurine in rat lung slices.
    Biochemical pharmacology, 1989, Feb-01, Volume: 38, Issue:3

    Topics: Animals; Cystamine; Cysteamine; Glutathione; In Vitro Techniques; Lung; Male; Paraquat; Putrescine; Rats; Rats, Inbred Strains; Taurine

1989
Cystamine-enkephalin dimer. Syntheses and biological activities of enkephalin analogs containing cystamine and cysteamine.
    International journal of peptide and protein research, 1986, Volume: 27, Issue:2

    Topics: Animals; Brain; Cell Membrane; Cystamine; Cysteamine; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalins; Indicators and Reagents; Rats; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, mu; Structure-Activity Relationship

1986
Synthesis and radioprotective activity of new cysteamine and cystamine derivatives.
    Journal of medicinal chemistry, 1986, Volume: 29, Issue:11

    Topics: Amifostine; Animals; Cystamine; Cysteamine; Female; Male; Mice; Radiation-Protective Agents; Structure-Activity Relationship

1986
Irreversible inactivation of calcium-dependent proteinases from rat liver by biological disulfides.
    FEBS letters, 1987, Jan-01, Volume: 210, Issue:1

    Topics: Animals; Calpain; Cystamine; Cysteamine; Cysteine; Cystine; Glutathione; Glutathione Disulfide; Kinetics; Liver; Male; Rats; Rats, Inbred Strains; Sulfhydryl Compounds

1987
The effect of cysteamine, cystamine, and the structurally related compounds taurine, N-acetyl-cysteine, and D-penicillamine on plasma prolactin levels in normal and estrogen-primed hyperprolactinemic rats.
    Endocrinology, 1987, Volume: 121, Issue:2

    Topics: Acetylcysteine; Animals; Cystamine; Cysteamine; Estradiol; Hyperprolactinemia; Male; Metoclopramide; Penicillamine; Prolactin; Rats; Taurine; Thyrotropin-Releasing Hormone

1987
Palmitoyl derivatives of L-cysteine, cysteamine, L-cystine, cystamine and their incorporation into the bilayers of unilamellar liposomes.
    Biochimica et biophysica acta, 1988, May-09, Volume: 940, Issue:1

    Topics: Amino Acids; Cystamine; Cysteamine; Cystine; Indicators and Reagents; Lipid Bilayers; Liposomes; Models, Biological; Palmitic Acids

1988
Cysteamine and cystamine.
    Methods in enzymology, 1987, Volume: 143

    Topics: Animals; Chromatography, High Pressure Liquid; Cystamine; Cysteamine; Dioxygenases; Glutathione; Indicators and Reagents; Kinetics; Liver; Oxygen Consumption; Oxygenases; Swine

1987
Persulfide sulfur is a growth factor for cells defective in sulfur metabolism.
    Biochemistry and cell biology = Biochimie et biologie cellulaire, 1986, Volume: 64, Issue:8

    Topics: Albumins; Animals; Cell Division; Cell Line; Cystamine; Cysteamine; Cysteine; Disulfides; Globulins; Growth Substances; Leukemia L1210; Mercaptoethanol; Mice; Serum Albumin, Bovine; Sulfhydryl Compounds

1986
Cooperative behavior in the thiol oxidation of rabbit muscle glycogen phosphorylase in cysteamine/cystamine redox buffers.
    The Journal of biological chemistry, 1986, Nov-25, Volume: 261, Issue:33

    Topics: Adenosine Monophosphate; Animals; Buffers; Chromatography, Gel; Cystamine; Cysteamine; Glutathione; Kinetics; Macromolecular Substances; Muscles; Oxidation-Reduction; Phosphorylases; Rabbits; Sulfhydryl Compounds

1986
Cysteamine depletes cystinotic leucocyte granular fractions of cystine by the mechanism of disulphide interchange.
    The Biochemical journal, 1985, Jun-15, Volume: 228, Issue:3

    Topics: Cystamine; Cysteamine; Cystine; Cystinosis; Cytoplasmic Granules; Disulfides; Ethylmaleimide; Half-Life; Humans; Leukocytes

1985
Structural requirements for cytoprotective agents in galactosamine-induced hepatic necrosis.
    Toxicology and applied pharmacology, 1985, Volume: 81, Issue:1

    Topics: Animals; Calcium; Chelating Agents; Chemical and Drug Induced Liver Injury; Cystamine; Cysteamine; Galactosamine; Liver Diseases; Male; Necrosis; Rats; Rats, Inbred Strains; Structure-Activity Relationship

1985
Hepatic cysteamine and non-protein sulfhydryl levels following cystamine or cysteamine treatment of galactosamine-poisoned rats.
    Drug and chemical toxicology, 1985, Volume: 8, Issue:6

    Topics: Animals; Chromatography, High Pressure Liquid; Cystamine; Cysteamine; Galactosamine; Liver; Male; Rats; Rats, Inbred Strains; Sulfhydryl Compounds; Time Factors

1985
[Vasomotor properties of mercaptoethylguanidine (MEG) in the rat].
    Archives internationales de pharmacodynamie et de therapie, 1965, Volume: 158, Issue:2

    Topics: Adrenal Medulla; Animals; beta-Aminoethyl Isothiourea; Blood Pressure; Cystamine; Cysteamine; Epinephrine; Guanidines; Histamine H1 Antagonists; Histamine Release; Norepinephrine; Rats; Sulfhydryl Compounds

1965
[Study of pharmacodynamic properties of cystamine and cysteamine in different animal species].
    Strahlentherapie, 1966, Volume: 131, Issue:3

    Topics: Animals; Blood Pressure; Capillary Permeability; Carotid Arteries; Cats; Chickens; Cystamine; Cysteamine; Edema; Female; Histamine Release; Homeostasis; Hypotension; Injections, Intraperitoneal; Injections, Intravenous; Jejunum; Lung; Male; Manometry; Methysergide; Mice; Nictitating Membrane; Rabbits; Serotonin; Skin

1966
[Effect of cystamine on respiration and glycolysis of erythrocytes].
    Folia haematologica (Leipzig, Germany : 1928), 1968, Volume: 89, Issue:2

    Topics: Cystamine; Cysteamine; Erythrocytes; Glucose; Glycolysis; NAD; Oxidoreductases; Peroxides; Reticulocytes

1968
Effects of cystamine and cysteamine on the adenosine-triphosphatase activity and oxidative phosphorylation of rat-liver mitochondria.
    The Biochemical journal, 1966, Volume: 98, Issue:3

    Topics: Adenosine Triphosphatases; Amines; Animals; Cystamine; Cysteamine; Dinitrophenols; In Vitro Techniques; Liver; Magnesium; Mitochondria; Oxidative Phosphorylation; Rats

1966
[Action of chemical radioprotectors on hypothalamic neurosecretion in rats exposed to ionizing radiations].
    Comptes rendus des seances de la Societe de biologie et de ses filiales, 1966, Volume: 160, Issue:11

    Topics: Animals; Cystamine; Cysteamine; Hypothalamus; Neurosecretion; Radiation-Protective Agents; Rats

1966
Radical formation in cysteamine free base and cystamine.2HCl by reaction with atomic hydrogen and by gamma-irradiation.
    International journal of radiation biology and related studies in physics, chemistry, and medicine, 1968, Volume: 14, Issue:5

    Topics: Chemical Phenomena; Chemistry; Cystamine; Cysteamine; Electron Spin Resonance Spectroscopy; Free Radicals; Hydrochloric Acid; Hydrogen; Radiation Effects

1968
EPR of fast repair reactions by sulfhydryl and disulfide compounds in aqueous solutions.
    Radiation research, 1970, Volume: 42, Issue:1

    Topics: Caffeine; Chemical Phenomena; Chemistry; Cystamine; Cysteamine; Cystine; Electron Spin Resonance Spectroscopy; Ethanol; Glucose; Hydroxides; Methods; Sulfhydryl Compounds; Sulfides; Thymine

1970
Studies on the mechanism of cystamine prevention of several liver structural and biochemical alterations caused by carbon tetrachloride.
    Toxicology and applied pharmacology, 1973, Volume: 24, Issue:1

    Topics: Acid Phosphatase; Animals; Body Temperature; Carbon Isotopes; Carbon Tetrachloride; Carbon Tetrachloride Poisoning; Cystamine; Cysteamine; Cytochrome Reductases; Glucose-6-Phosphatase; In Vitro Techniques; Lipid Metabolism; Liver; Lysosomes; Male; Methyltransferases; Microsomes, Liver; Oxidation-Reduction; Rats; Ribonucleases; Time Factors

1973
[Studies on the mechanism of the radioprotective action of thiol and disulfide compounds on models of elementary biological units].
    Zeitschrift fur Naturforschung. Teil B, Chemie, Biochemie, Biophysik, Biologie und verwandte Gebiete, 1966, Volume: 21, Issue:2

    Topics: Cobalt Isotopes; Coliphages; Cystamine; Cysteamine; DNA, Viral; Models, Biological; Oxygen; Radiation Effects

1966
Effect of daily or 4-hourly administrations of lathyrogens on the eruption rates of impeded and unimpeded mandibular incisors of rats.
    Archives of oral biology, 1974, Volume: 19, Issue:12

    Topics: Acetamides; Aminopropionitrile; Animals; Cystamine; Cysteamine; Incisor; Injections, Subcutaneous; Male; Mandible; Methylamines; Nitriles; Rats; Time Factors; Tooth Eruption

1974
Protection of DNA molecules of cultured mammalian cells from radiation-induced single-strand scissions by various alcohols and SH compounds.
    International journal of radiation biology and related studies in physics, chemistry, and medicine, 1972, Volume: 21, Issue:4

    Topics: Alcohols; Animals; Butanols; Carbon Isotopes; Cell Line; Cells, Cultured; Centrifugation, Density Gradient; Cystamine; Cysteamine; Cysteine; DNA; DNA, Neoplasm; DNA, Single-Stranded; Ethanol; Free Radicals; Glycerol; Glycols; Isotope Labeling; Leukemia, Experimental; Mathematics; Mercaptoethanol; Methanol; Mice; Radiation Effects; Radiation-Protective Agents; Sulfhydryl Compounds; Thymidine; Time Factors

1972
Prenatal fractionated x-irradiation and chemical radiation protection.
    Strahlentherapie, 1972, Volume: 144, Issue:4

    Topics: Animals; Body Weight; Cystamine; Cysteamine; Female; Fetus; Gestational Age; Infant Mortality; Pregnancy; Radiation Dosage; Radiation Genetics; Radiation-Protective Agents; Rats

1972
[Formation of fluorescent pigments in lipids].
    Nauchnye doklady vysshei shkoly. Biologicheskie nauki, 1973, Volume: 115, Issue:7

    Topics: Aldehydes; Animals; beta-Aminoethyl Isothiourea; Cystamine; Cysteamine; Epinephrine; Ethers, Cyclic; Fluorescence; Gallic Acid; Histamine; Hydroxylamines; Intestine, Small; Ketones; Lipid Metabolism; Male; Mice; Oleic Acids; Peroxides; Pigments, Biological; Radiation-Protective Agents; Serotonin; Spectrum Analysis; Spleen; Temperature; Tryptamines; Vitamin E

1973
Heritable damage following prenatal fractionated x-irradiation in rats.
    Strahlentherapie, 1973, Volume: 146, Issue:6

    Topics: Animals; Cystamine; Cysteamine; Female; Fertility; Fetal Death; Fetus; Genes, Dominant; Genes, Lethal; Infertility, Female; Infertility, Male; Male; Mutation; Pregnancy; Radiation Injuries, Experimental; Radiation-Protective Agents; Rats

1973
[pH and cuntaneous radiation-protective effect of cysteamine].
    Strahlentherapie, 1973, Volume: 145, Issue:6

    Topics: Animals; Cystamine; Cysteamine; Disulfides; Hair; Hydrogen-Ion Concentration; Hypoxia; Mice; Oxygen; Radiation Effects; Radiation-Protective Agents; Skin; Skin Absorption

1973
Formation of three-dimensional structure in proteins. I. Rapid nonenzymic reactivation of reduced lysozyme.
    Biochemistry, 1970, Dec-08, Volume: 9, Issue:25

    Topics: Air; Animals; Chemical Phenomena; Chemistry; Chickens; Chromatography, Ion Exchange; Circular Dichroism; Cystamine; Cysteamine; Cysteine; Cystine; Edetic Acid; Glutathione; Kinetics; Models, Chemical; Muramidase; Oxidation-Reduction; Protein Denaturation; Sulfhydryl Compounds; Sulfides; Temperature; Time Factors

1970
[Studies on the enhancement of the radiation-protecting action of anabolic steroids].
    Strahlentherapie, 1972, Volume: 143, Issue:5

    Topics: Animals; Benzoates; Benzyl Compounds; Cystamine; Cysteamine; DNA; Drug Synergism; Female; Hydroxybutyrates; Leukocytes; Lymphocytes; Methandrostenolone; Methyl Ethers; Peptides; Radiation-Protective Agents; Rats; Rats, Inbred Strains; Succinates; Tryptamines

1972
The rejoining of x-ray-induced strand breaks in the DNA of a murine lymphoma cell (L5178Y).
    Biochimica et biophysica acta, 1971, Feb-25, Volume: 232, Issue:1

    Topics: Animals; Cell Line; Centrifugation, Density Gradient; Cystamine; Cysteamine; Dactinomycin; DNA, Neoplasm; Leucine; Lymphoma; Mathematics; Mice; Neoplasm Proteins; Puromycin; Radiation Effects; RNA, Neoplasm; Temperature; Thymidine; Tritium; Uridine

1971
Protection against x-irradiation by sulphdryl compounds. I. Studies on the cellular uptake under various conditions of incubation.
    International journal of radiation biology and related studies in physics, chemistry, and medicine, 1967, Volume: 13, Issue:1

    Topics: Culture Techniques; Cystamine; Cysteamine; Cysteine; Glutathione; Hydrogen-Ion Concentration; Radiation Effects; Radiation-Protective Agents; Sulfhydryl Compounds; Sulfur Isotopes; Temperature; Thioglycolates

1967
[On the subject of the protective action of cysteamine and cystamine in rats having received lethal doses of Myleran].
    Pathologie et biologie, 1966, Volume: 14, Issue:9

    Topics: Animals; Busulfan; Cystamine; Cysteamine; Rats

1966
Quantitative determination of biologically important thiols and disulfides by gas-liquid chromatography.
    Analytical biochemistry, 1969, Oct-01, Volume: 31, Issue:1

    Topics: Aldehydes; Chromatography, Gas; Cystamine; Cysteamine; Cysteine; Cystine; Homocysteine; Homocystine; Hot Temperature; Hydrogen-Ion Concentration; Lactones; Methionine; Methods; Penicillamine; Sulfhydryl Compounds; Sulfides

1969
[Role of endogenous histamine in the protective effect of radiation-protective agents].
    Doklady Akademii nauk SSSR, 1970, Volume: 191, Issue:4

    Topics: Animals; beta-Aminoethyl Isothiourea; Cystamine; Cysteamine; Cysteine; Gastric Mucosa; Histamine; Kidney; Liver; Male; Radiation Injuries, Experimental; Radiation-Protective Agents; Rats; Serine; Serotonin; Skin; Snakes; Venoms

1970
The enzymatic breakdown of pantethine to pantothenic acid and cystamine.
    European journal of biochemistry, 1970, Volume: 16, Issue:3

    Topics: Amidohydrolases; Animals; Carbon Isotopes; Cattle; Chemical Phenomena; Chemical Precipitation; Chemistry; Chromatography, DEAE-Cellulose; Cystamine; Cysteamine; Electrophoresis; Horses; Hot Temperature; Hydrogen-Ion Concentration; Hydrolases; Hydroxybutyrates; Kidney; Pantothenic Acid; Quaternary Ammonium Compounds; Species Specificity; Sulfates; Sulfides; Swine

1970
Cysteamine, cystamine, and single-strand breaks of DNA in cultured mammalian cells.
    Radiation research, 1970, Volume: 44, Issue:1

    Topics: Animals; Carbon Isotopes; Cell Line; Centrifugation, Density Gradient; Culture Techniques; Cystamine; Cysteamine; DNA; Leukemia, Experimental; Mice; Radiation Effects; Sulfhydryl Compounds; Thymidine

1970
[The effect of sulfur-containing radioprotective substances on tissue respiration and phosphorylation].
    Biulleten' eksperimental'noi biologii i meditsiny, 1967, Volume: 64, Issue:8

    Topics: Animals; beta-Aminoethyl Isothiourea; Columbidae; Cystamine; Cysteamine; Erythrocytes; Liver; Oxidative Phosphorylation; Oxygen Consumption; Rats

1967
Neurosecretion in the hypothalamus and posterior pituitary after irradiation and injection of chemical radioprotectors in the rat.
    Radiation research, 1968, Volume: 34, Issue:3

    Topics: Animals; Cesium Isotopes; Cystamine; Cysteamine; Histocytochemistry; Hypothalamus; Injections, Intraperitoneal; Male; Neurosecretion; Pituitary Gland, Posterior; Radiation Effects; Radiation-Protective Agents; Rats

1968
The state of shock induced by cystamine and cysteamine.
    British journal of pharmacology, 1968, Volume: 34, Issue:1

    Topics: Animals; Blood Pressure; Blood Proteins; Carbohydrate Metabolism; Cystamine; Cysteamine; DNA Nucleotidyltransferases; Endoplasmic Reticulum; Enzymes; In Vitro Techniques; Liver; Liver Regeneration; Mitochondria; Mitosis; Neuraminic Acids; Nucleic Acids; Oxygen Consumption; Rats; Shock, Septic; Thymidine Kinase; Time Factors

1968
A differential polarographic study on radioprotective substances containing sulfhydryl.
    Experientia, 1968, Sep-15, Volume: 24, Issue:9

    Topics: beta-Aminoethyl Isothiourea; Cystamine; Cysteamine; Cysteine; Glutathione; Polarography; Serum Albumin, Bovine; Sulfhydryl Compounds

1968
Toxicity of radioprotective agents to yeast.
    Radiation research, 1969, Volume: 39, Issue:1

    Topics: Cystamine; Cysteamine; Cysteine; Oxygen Consumption; Radiation-Protective Agents; Saccharomyces; Time Factors

1969
Studies on the metabolism of Tetrahymena pyriformis GL. V. Protective effect of sulphydryl substances against gamma-irradiation.
    Enzymologia, 1969, Jun-30, Volume: 36, Issue:6

    Topics: beta-Aminoethyl Isothiourea; Cobalt Isotopes; Cystamine; Cysteamine; Cysteine; Dimercaprol; Glutathione; Hydrogen Peroxide; Oxygen Consumption; Radiation Effects; Radiation-Protective Agents; Sulfhydryl Compounds; Tetrahymena

1969
[Comparison of the radiation protective effects of cystamine and cysteamine on the skin].
    Strahlentherapie, 1969, Volume: 137, Issue:2

    Topics: Animals; Blood Volume; Cystamine; Cysteamine; Erythrocytes; Injections, Intradermal; Injections, Intraperitoneal; Liver; Mice; Oxygen Consumption; Plasma; Plasma Volume; Rabbits; Radiation Effects; Radiation-Protective Agents; Rats; Skin; Spleen

1969
[Effects of sulfur-containing radiation-protective drugs on biochemical changes in irradiation of the organism].
    Radiobiologiia, 1965, Volume: 5, Issue:3

    Topics: Adenosine Triphosphate; Animals; Cystamine; Cysteamine; In Vitro Techniques; Nucleic Acids; Radiation Injuries, Experimental; Rats

1965
[Catalysis of the oxidation of cysteamine to cystamine by the sulfur-sulfide system].
    Bollettino della Societa italiana di biologia sperimentale, 1964, Sep-30, Volume: 40, Issue:18

    Topics: Catalysis; Cystamine; Cysteamine; Oxygen Consumption; Sulfides; Sulfur

1964
Importance for radioprotective effect in mammals of pharmacological and biochemical actions of cysteamine and related substances.
    Annali dell'Istituto superiore di sanita, 1965, Volume: 1, Issue:9

    Topics: Animals; Cystamine; Cysteamine; Mice; Mitochondria, Liver; Radiation Injuries, Experimental; Radiation-Protective Agents; Rats; Time Factors

1965
Effects of some radioprotective substances upon pre-natal survival of offspring to roentgen irradiated male mice.
    Acta radiologica: therapy, physics, biology, 1966, Volume: 4, Issue:5

    Topics: Animals; beta-Aminoethyl Isothiourea; Cystamine; Cysteamine; Female; Glutathione; Male; Mutation; Pregnancy; Pregnancy, Animal; Radiation Effects; Radiation-Protective Agents; Rats; Serotonin; Spermatozoa

1966
Effects of cystamine and cysteamine on the peroxidation of lipids and the release of proteins from mitochondria.
    The Biochemical journal, 1966, Volume: 101, Issue:1

    Topics: Animals; Cystamine; Cysteamine; Glutathione; In Vitro Techniques; Lipid Metabolism; Liver; Mitochondria; Peroxides; Proteins; Rats

1966
[The effect of radiation-protective agents (anoxia, cysteamine and cystamine) on the sulfhydryl group content of Ehrlich ascites tumor cells].
    Doklady Akademii nauk SSSR, 1966, Feb-01, Volume: 166, Issue:4

    Topics: Animals; Carcinoma, Ehrlich Tumor; Culture Techniques; Cystamine; Cysteamine; Hypoxia; Mice; Neoplasm Proteins; Sulfhydryl Compounds

1966
Studies on latent derivatives of aminoethanethiols as potentially selective cytoprotectants. I. A spectrophotometric assay for aminoethanethiols in biologic media.
    Cancer research, 1967, Volume: 27, Issue:1

    Topics: Animals; Cystamine; Cysteamine; Glycols; In Vitro Techniques; Kidney; Pyruvates; Rats; Spectrophotometry; Sulfhydryl Compounds; Sulfites

1967
Reduction of the secretory response to Escherichia coli heat-stable enterotoxin by thiol and disulfide compounds.
    Infection and immunity, 1983, Volume: 41, Issue:1

    Topics: Acetylcysteine; Animals; Bacterial Toxins; Body Fluids; Cyclic GMP; Cystamine; Cystathionine; Cysteamine; Cysteine; Cystine; Disulfides; Enterotoxins; Enzyme Activation; Escherichia coli Proteins; Guanylate Cyclase; Intestinal Mucosa; Mice; Rats; Rats, Inbred Strains; Sulfhydryl Compounds

1983
Reactivation by cysteamine of vascular alpha adrenoceptors blocked by the tetramine disulfide benextramine and interaction of benextramine with phenoxybenzamine.
    Canadian journal of physiology and pharmacology, 1980, Volume: 58, Issue:12

    Topics: Animals; Aorta; Cystamine; Cysteamine; Dose-Response Relationship, Drug; In Vitro Techniques; Muscle, Smooth, Vascular; Myocardial Contraction; Norepinephrine; Phenoxybenzamine; Rats; Receptors, Adrenergic; Receptors, Adrenergic, alpha

1980
Protection with combinations of hydroxytryptophan and some thiol compounds against whole-body gamma irradiation.
    International journal of radiation biology and related studies in physics, chemistry, and medicine, 1983, Volume: 44, Issue:2

    Topics: Animals; beta-Aminoethyl Isothiourea; Cobalt Radioisotopes; Cystamine; Cysteamine; Cysteine; Drug Therapy, Combination; Gamma Rays; Injections, Intraperitoneal; Mice; Mice, Inbred Strains; Radiation Injuries, Experimental; Radiation-Protective Agents; Serotonin; Sulfhydryl Compounds; Tiopronin; Whole-Body Irradiation

1983
Determination of cystamine by high-performance liquid chromatography.
    Analytical biochemistry, 1984, Volume: 136, Issue:2

    Topics: Animals; Chromatography, High Pressure Liquid; Chromatography, Ion Exchange; Cystamine; Cysteamine; Male; Rats; Rats, Inbred Strains; Tissue Distribution

1984
Characterization of the protective effect of radioprotective substances by means of long-term changes in oxygen consumption.
    Strahlentherapie, 1980, Volume: 156, Issue:11

    Topics: 5-Methoxytryptamine; Animals; beta-Aminoethyl Isothiourea; Cystamine; Cysteamine; Fluoroacetates; Hypothermia; Male; Mathematics; Mice; Oxygen Consumption; Radiation Dosage; Serotonin; Time Factors; Tryptamines

1980
Cytotoxic effects of ultrasound in vitro dependence on gas content, frequency, radical scavengers, and attachment.
    Radiation research, 1982, Volume: 89, Issue:2

    Topics: Animals; Cell Adhesion; Cell Line; Cell Survival; Cricetinae; Cricetulus; Cystamine; Cysteamine; Gases; Ultrasonics

1982
Cystamine inhibits HIV type 1 replication in cells of monocyte/macrophage and T cell lineages.
    AIDS research and human retroviruses, 1995, Volume: 11, Issue:4

    Topics: Antiviral Agents; Cell Line; Cells, Cultured; Cystamine; Cysteamine; Granulocyte-Macrophage Colony-Stimulating Factor; HIV-1; Humans; Interleukin-6; Lipopolysaccharides; Macrophages; Monocytes; T-Lymphocytes; Tumor Necrosis Factor-alpha; Virus Replication

1995
Glutaredoxin accelerates glutathione-dependent folding of reduced ribonuclease A together with protein disulfide-isomerase.
    The Journal of biological chemistry, 1995, Apr-07, Volume: 270, Issue:14

    Topics: Catalysis; Cystamine; Cysteamine; Escherichia coli; Glutaredoxins; Glutathione; Isomerases; Oxidation-Reduction; Oxidoreductases; Protein Disulfide-Isomerases; Protein Folding; Proteins; Ribonuclease, Pancreatic; Sodium Selenite

1995
[1H-NMR spectroscopic study of cysteamine eyedrops].
    Klinische Monatsblatter fur Augenheilkunde, 1995, Volume: 206, Issue:4

    Topics: Cornea; Corneal Diseases; Cystamine; Cysteamine; Cystinosis; Dose-Response Relationship, Drug; Drug Stability; Humans; Magnetic Resonance Spectroscopy; Ophthalmic Solutions; Oxidation-Reduction

1995
Thioltransferase can utilize cysteamine as same as glutathione as a reductant during the restoration of cystamine-treated glucose 6-phosphate dehydrogenase activity.
    Biochemistry and molecular biology international, 1994, Volume: 34, Issue:4

    Topics: Animals; Cystamine; Cysteamine; Cysteine; Dithiothreitol; Enzyme Reactivators; Glucosephosphate Dehydrogenase; Glutaredoxins; Glutathione; Humans; Liver; Mercaptoethanol; Oxidation-Reduction; Oxidoreductases; Protein Disulfide Reductase (Glutathione); Rabbits

1994
Effects of CaBP2, the rat analog of ERp72, and of CaBP1 on the refolding of denatured reduced proteins. Comparison with protein disulfide isomerase.
    The Journal of biological chemistry, 1994, Jan-28, Volume: 269, Issue:4

    Topics: Animals; Calcium-Binding Proteins; Creatine Kinase; Cricetinae; Cystamine; Cysteamine; Disulfides; Humans; Immunoglobulin Fab Fragments; Isomerases; Kinetics; Membrane Glycoproteins; Mice; Protein Denaturation; Protein Disulfide-Isomerases; Protein Folding; Rats; Ribonucleases; Sulfur-Sulfur Bond Isomerases

1994
Determination of cysteamine and cystamine by gas chromatography with flame photometric detection.
    Journal of pharmaceutical and biomedical analysis, 1993, Volume: 11, Issue:10

    Topics: Animals; Chromatography, Gas; Cystamine; Cysteamine; Gas Chromatography-Mass Spectrometry; Male; Mice; Mice, Inbred Strains; Oxidation-Reduction; Reproducibility of Results; Tissue Distribution

1993
Thiol and disulfide determination by free zone capillary electrophoresis.
    Journal of biochemical and biophysical methods, 1993, Volume: 26, Issue:4

    Topics: Animals; Cattle; Cystamine; Cysteamine; Cysteine; Cystine; Disulfides; Dithiothreitol; Electrophoresis; Glutathione; Glutathione Disulfide; Oxidation-Reduction; Sensitivity and Specificity; Sulfhydryl Compounds

1993
Cysteamine oxidation by lentil seedling amine oxidase.
    Biochemistry and molecular biology international, 1997, Volume: 41, Issue:2

    Topics: Amine Oxidase (Copper-Containing); Cystamine; Cysteamine; Fabaceae; Kinetics; Models, Chemical; Oxidation-Reduction; Oxidoreductases Acting on CH-NH Group Donors; Oxygen; Plants, Medicinal

1997
Synthesis and antitumour effect of the melanogenesis-based antimelanoma agent N-propionyl-4-S-cysteaminylphenol.
    Biochemical pharmacology, 1998, Jun-15, Volume: 55, Issue:12

    Topics: Animals; Antineoplastic Agents; Cystamine; Cysteamine; Humans; Hypopigmentation; Melanins; Melanoma, Experimental; Mice; Mice, Inbred C57BL; Phenols; Skin Neoplasms; Tumor Cells, Cultured

1998
Effects of cysteamine and cystamine on the sonochemical accumulation of hydrogen peroxide--implications for their mechanisms of action in ultrasound-exposed cells.
    Free radical biology & medicine, 1999, Volume: 26, Issue:7-8

    Topics: Argon; Cell Survival; Cystamine; Cysteamine; Electron Spin Resonance Spectroscopy; Free Radical Scavengers; Free Radicals; Hydrogen Peroxide; Indicators and Reagents; Models, Chemical; Photolysis; Ultrasonics

1999
Sulfur containing tyrosine analogs can cause selective melanocytotoxicity involving tyrosinase-mediated apoptosis.
    The journal of investigative dermatology. Symposium proceedings, 1999, Volume: 4, Issue:2

    Topics: Animals; Antineoplastic Agents; Apoptosis; Cell Line; COS Cells; Cystamine; Cysteamine; Female; Hair Color; Hair Follicle; Humans; Kinetics; Melanocytes; Mice; Mice, Inbred C57BL; Microscopy, Electron; Monophenol Monooxygenase; Oxidative Stress; Phenols; Pregnancy; Transfection

1999
Selective incorporation and specific cytocidal effect as the cellular basis for the antimelanoma action of sulphur containing tyrosine analogs.
    The Journal of investigative dermatology, 1999, Volume: 113, Issue:6

    Topics: Animals; Antineoplastic Agents; Cell Cycle; Cell Division; Cell Line; Cystamine; Cysteamine; DNA; Dose-Response Relationship, Drug; Flow Cytometry; HeLa Cells; Humans; Melanoma; Mice; Monophenol Monooxygenase; Phenols

1999
Reversible protection of disulfide bonds followed by oxidative folding render recombinant hCGbeta highly immunogenic.
    Vaccine, 2000, Mar-06, Volume: 18, Issue:17

    Topics: Animals; Antibodies; Chorionic Gonadotropin, beta Subunit, Human; Contraception, Immunologic; Cystamine; Cysteamine; Disulfides; DNA, Bacterial; Endotoxins; Escherichia coli; Female; Haplorhini; Humans; Inclusion Bodies; Lymphocyte Activation; Oxidation-Reduction; Protein Denaturation; Protein Folding; Rats; Rats, Wistar; Recombinant Proteins; Reproducibility of Results; Sequence Analysis, Protein; Sulfites; Tetrathionic Acid

2000
Comparison of in vitro cytotoxicity of N-acetyl and N-propionyl derivatives of phenolic thioether amines in melanoma and neuroblastoma cells and the relationship to tyrosinase and tyrosine hydroxylase enzyme activity.
    Melanoma research, 2000, Volume: 10, Issue:1

    Topics: Amides; Antineoplastic Agents; Cell Division; Cystamine; Cysteamine; Growth Inhibitors; HeLa Cells; Humans; Melanoma; Monophenol Monooxygenase; Neuroblastoma; Phenols; Tumor Cells, Cultured; Tyrosine 3-Monooxygenase

2000
Comparison of different protein immobilization methods on quartz crystal microbalance surface in flow injection immunoassay.
    Analytical biochemistry, 2001, Dec-15, Volume: 299, Issue:2

    Topics: Absorption; Animals; Biosensing Techniques; Complement C3; Crystallization; Cystamine; Cysteamine; Equipment Reuse; Fatty Acids; Flow Injection Analysis; Goats; Humans; Immunoassay; Quartz; Serum Albumin; Surface Properties

2001
[Metabolism of cysteamine and of cystamine in the rabbit and the dog].
    Archives internationales de physiologie, 1954, Volume: 62, Issue:1

    Topics: Animals; Cystamine; Cysteamine; Dogs; Ethylamines; Rabbits

1954
[Effect of cysteamine and cystamine on myoneural junction].
    Archives internationales de physiologie et de biochimie, 1954, Volume: 62, Issue:4

    Topics: Cystamine; Cysteamine; Ethylamines; Neuromuscular Junction

1954
Cysteamine-cystamine: intestinal absorption, distribution among various organs and excretion.
    Archives internationales de physiologie et de biochimie, 1954, Volume: 62, Issue:4

    Topics: Biological Transport; Body Fluids; Cystamine; Cysteamine; Ethylamines; Humans; Intestinal Absorption; Intestines

1954
[Cysteamine cystamine; effect on uptake and biological half-life of radioactive iodine in the thyroid gland of rats].
    Archives internationales de physiologie et de biochimie, 1954, Volume: 62, Issue:4

    Topics: Animals; Cystamine; Cysteamine; Ethylamines; Half-Life; Iodine; Iodine Radioisotopes; Radioisotopes; Rats; Thyroid Gland

1954
The metabolism of cystamine and cysteamine; studies on the formation of taurine in mammals.
    Scandinavian journal of clinical and laboratory investigation, 1954, Volume: 6 Suppl. 13

    Topics: Animals; Bile Acids and Salts; Cystamine; Cysteamine; Ethylamines; Mammals; Salts; Taurine

1954
[Antihistaminic properties of decarboxylated derivatives of cysteine (cysteamine and cystamine)].
    Archives internationales de physiologie et de biochimie, 1955, Volume: 63, Issue:3

    Topics: Anti-Allergic Agents; Cystamine; Cysteamine; Cysteine; Decarboxylation; Ethylamines; Histamine H1 Antagonists

1955
The effects of ionizing radiation on aqueous solutions of cysteamine and cystamine.
    Radiation research, 1955, Volume: 3, Issue:3

    Topics: Cystamine; Cysteamine; Ethylamines; Radiation Effects; Radiation, Ionizing

1955
The effect of cysteamine, cystamine and hypoxia on mortality and bone marrow chromosome aberrations in mice after total body roentgen irradiation.
    Acta radiologica, 1955, Volume: 44, Issue:3

    Topics: Animals; Bone Marrow; Chromosome Aberrations; Chromosome Disorders; Cystamine; Cysteamine; Cysteine; Hypoxia; Mice; Radiation; Whole-Body Irradiation; X-Rays

1955
[Effect of cysteamine, cystamine and cystein on the growth of mouse ascites tumor].
    Arzneimittel-Forschung, 1955, Volume: 5, Issue:11

    Topics: Animals; Ascites; Carcinoma, Ehrlich Tumor; Cystamine; Cysteamine; Cysteine; Ethylamines; Mice; Neoplasms, Experimental

1955
[Mechanism of action of cysteamine and cystamine on the adrenal medulla].
    Archives internationales de physiologie et de biochimie, 1955, Volume: 63, Issue:4

    Topics: Adrenal Medulla; Cystamine; Cysteamine; Ethylamines; Ganglia; Ganglia, Autonomic; Humans

1955
Experimental and clinical research on the radioprotective action of cysteamine and cystamine. I. Experimental research on unicellular organisms.
    The British journal of radiology, 1956, Volume: 29, Issue:347

    Topics: Biomedical Research; Cystamine; Cysteamine; Escherichia coli; Mercaptoethylamines; Radiation Protection

1956
On the mode of action of x-ray protective agents. I. The fixation in vivo of cystamine and cysteamine to proteins.
    The Journal of biological chemistry, 1956, Volume: 223, Issue:1

    Topics: Cystamine; Cysteamine; Mercaptoethylamines; Protective Agents; X-Rays

1956
Experimental and clinical research on the radio-protective action of cysteamine and cystamine. II. Experimental research upon mammals.
    The British journal of radiology, 1957, Volume: 30, Issue:350

    Topics: Animals; Biomedical Research; Cystamine; Cysteamine; Mammals; Mercaptoethylamines

1957
Late effects of gamma radiation on mice protected with cysteamine or cystamine.
    Nature, 1957, Jan-26, Volume: 179, Issue:4552

    Topics: Animals; Cystamine; Cysteamine; Gamma Rays; Mercaptoethylamines; Mice; Neoplasms; Neoplasms, Experimental; Radiation Protection

1957
Relative value of cysteamine and cystamine as radioprotective agents for fetal and adult mice.
    The American journal of physiology, 1957, Volume: 189, Issue:1

    Topics: Animals; Cystamine; Cysteamine; Fetus; Mercaptoethylamines; Mice; Radiation Protection; Radiation-Protective Agents

1957
Experimental and clinical research on the radio-protective action of cysteamine and cystamine. III. Clinical research.
    The British journal of radiology, 1957, Volume: 30, Issue:353

    Topics: Animals; Biomedical Research; Cystamine; Cysteamine; Mercaptoethylamines; Radiation Protection

1957
[Effect of cysteamine and cystamine on thymocytes in vitro].
    Comptes rendus des seances de la Societe de biologie et de ses filiales, 1957, Volume: 151, Issue:1

    Topics: Cystamine; Cysteamine; In Vitro Techniques; Mercaptoethylamines; Thymocytes

1957
Studies on the sulphur metabolism of tissues cultivated in vitro. III. Interrelationships between cysteine, methionine, cysteamine, and cystamine.
    Canadian journal of biochemistry and physiology, 1957, Volume: 35, Issue:10

    Topics: Amino Acids; Biochemical Phenomena; Cystamine; Cysteamine; Cysteine; In Vitro Techniques; Methionine; Sulfur

1957
[Effect of cysteamine and cystamine on irradiated thymocytes in vivo and in vitro].
    Comptes rendus des seances de la Societe de biologie et de ses filiales, 1957, Volume: 151, Issue:2

    Topics: Cystamine; Cysteamine; In Vitro Techniques; Mercaptoethylamines; Radiation; Thymocytes; Thymus Gland

1957
[Effects of cysteamine & cystamine on regeneration of the irradiated spleen in vitro].
    Comptes rendus des seances de la Societe de biologie et de ses filiales, 1957, Volume: 151, Issue:3

    Topics: Cystamine; Cysteamine; In Vitro Techniques; Mercaptoethylamines; Regeneration; Spleen; X-Rays

1957
Radioprotective properties of cystamine, cysteamine and cysteine when tested with chick fibroblasts in vitro.
    Nature, 1958, Feb-01, Volume: 181, Issue:4605

    Topics: Animals; Chickens; Cystamine; Cysteamine; Cysteine; Fibroblasts; In Vitro Techniques; Mercaptoethylamines; Radiation; Radiation Protection; Research Design; Tissue Culture Techniques

1958
[Toxicity of cysteamine and cystamine for thymocytes maintained in heterologous serum].
    Comptes rendus des seances de la Societe de biologie et de ses filiales, 1958, Volume: 152, Issue:1

    Topics: Cystamine; Cysteamine; Mercaptoethylamines; Thymocytes; Thymus Gland

1958
[Acclimatization to hypoxia associated with cystamine and cysteamine as a method of prevention of radiation sickness].
    Meditsinskaia radiologiia, 1959, Volume: 4, Issue:1

    Topics: Acclimatization; Biomedical Research; Cystamine; Cysteamine; Hypoxia; Mercaptoethylamines; Radiation Injuries; Radiation Protection

1959
[Effects of cysteamine & cystamine on reduction of the average life of mice after two successive doses of x-rays].
    Comptes rendus des seances de la Societe de biologie et de ses filiales, 1959, Volume: 153, Issue:1

    Topics: Animals; Cystamine; Cysteamine; Life; Mercaptoethylamines; Mice; Radiation Protection; X-Rays

1959
[The effect of cysteamine, cystamine and ethanolamine on the isolated virgin uterus of the cat].
    Comptes rendus des seances de la Societe de biologie et de ses filiales, 1960, Volume: 154

    Topics: Amino Alcohols; Animals; Cats; Cystamine; Cysteamine; Ethanolamine; Ethanolamines; Felis; Female; Humans; Mercaptoethylamines; Uterus

1960
Production of S-sulfo-cysteine and S-sulfo-cysteamine from cystine and cystamine, coupled to enzymic transamination and deamination of cysteinesulfinic acid.
    Biochimica et biophysica acta, 1961, Feb-18, Volume: 47

    Topics: Amidohydrolases; Cystamine; Cysteamine; Cysteine; Cystine; Deamination; Mercaptoethylamines; Sulfanilamide; Sulfanilamides; Sulfonamides; Transaminases

1961
[Action of cysteamine and cystamine on the acetylation of sulfanilamide in vitro].
    Comptes rendus des seances de la Societe de biologie et de ses filiales, 1960, Volume: 154

    Topics: Acetylation; Cystamine; Cysteamine; In Vitro Techniques; Mercaptoethylamines; Protein Processing, Post-Translational; Sulfanilamide; Sulfanilamides

1960
[Action of cysteamine and cystamine on the metabolism of the kidney and liver of the male rat poisoned by sodium fluoroacetate].
    Archives internationales de physiologie et de biochimie, 1961, Volume: 69

    Topics: Animals; Cystamine; Cysteamine; Fluoroacetates; Kidney; Liver; Male; Mercaptoethylamines; Rats

1961
The pharmacology of radioprotective chemicals. On some of the effects of beta-mercaptoethylamine (MEA) and cystamine in the rat.
    Radiation research, 1962, Volume: 16

    Topics: Animals; Cystamine; Cysteamine; Mercaptoethylamines; Radiation Protection; Rats

1962
Protection of cells in tissue culture by means of cysteamine and cystamine against the action of nitrogen mustard and x-rays.
    Biochemical pharmacology, 1961, Volume: 8

    Topics: Cystamine; Cysteamine; Mechlorethamine; Mercaptoethylamines; Nitrogen Mustard Compounds; Radiation Effects; Research Design; Tissue Culture Techniques; X-Rays

1961
[Early distribution of radioactivity in rat organs after injection of S35-cystamine and S35-cysteamine. II. Determination of radioactivity and conclusions].
    Comptes rendus des seances de la Societe de biologie et de ses filiales, 1963, Jul-10, Volume: 157

    Topics: Animals; Cystamine; Cysteamine; Hematologic Tests; Injections; Prothrombin; Radioactivity; Rats; Sulfur Isotopes

1963
[On the cardiovascular properties of cysteamine in the rat].
    Comptes rendus des seances de la Societe de biologie et de ses filiales, 1963, Jul-10, Volume: 157

    Topics: Animals; Blood Pressure; Blood Pressure Determination; Cardiovascular System; Cystamine; Cysteamine; Epinephrine; Rats

1963
[Early distribution of radioactivity in the organs of the rat after injection of S35-cystamine and S35-cysteamine. I. Introduction and autoradiographic results].
    Comptes rendus des seances de la Societe de biologie et de ses filiales, 1963, Jul-10, Volume: 157

    Topics: Animals; Autoradiography; Cystamine; Cysteamine; Injections; Radioactivity; Rats; Sulfur Isotopes

1963
[Effect of cystamine and cysteamine on the mitotic rhythm of an Ehrlich tumor].
    Comptes rendus des seances de la Societe de biologie et de ses filiales, 1963, Volume: 157

    Topics: Animals; Carcinoma; Carcinoma, Ehrlich Tumor; Cell Division; Cystamine; Cysteamine; Physiological Phenomena

1963
Transfer of radiation-induced unpaired spins from proteins to sulfur compounds.
    Radiation research, 1963, Volume: 18

    Topics: Animals; Cattle; Cystamine; Cysteamine; Proteins; Radiation; Radiation Effects; Research; Serum Albumin; Serum Albumin, Bovine; Sulfur Compounds; Thiocyanates

1963
Protection of tissueculture cells against ionizing radiation. I. The effect of biological amines, disulphide compounds and thiols.
    International journal of radiation biology and related studies in physics, chemistry, and medicine, 1962, Volume: 5

    Topics: Amines; Cystamine; Cysteamine; Cysteine; Cystine; Epinephrine; Histamine; Norepinephrine; Radiation-Protective Agents; Radiation, Ionizing; Serotonin; Sulfhydryl Compounds; Tissue Culture Techniques

1962
[Studies on biological radiation protection. 48. Quantitative relations in radiation protection with cysteamine].
    Strahlentherapie, 1963, Volume: 120

    Topics: Cystamine; Cysteamine; Radiation Protection; Radiation-Protective Agents

1963
[MECHANISM OF ACTION OF RADIOSENSITIZING AND RADIOPROTECTIVE COMPOUNDS ON E. COLI B].
    Nordisk medicin, 1963, Oct-17, Volume: 70

    Topics: Cystamine; Cysteamine; Escherichia coli; Oxygen; Radiation Effects; Radiation-Sensitizing Agents; Research

1963
SEPARATION OF CYSTEINE AND ITS OXIDATION PRODUCTS BY PAPER AND THIN-LAYER CHROMATOGRAPHY.
    Journal of chromatography, 1963, Volume: 12

    Topics: Autoradiography; Chromatography; Chromatography, Thin Layer; Cystamine; Cysteamine; Cysteine; Cystine; Oxidation-Reduction; Research; Sulfur Isotopes

1963
METHAEMOGLOBIN FORMATION INDUCED BY THIOLS.
    Biochemical pharmacology, 1963, Volume: 12

    Topics: Carbamates; Cystamine; Cysteamine; Ergothioneine; Esters; Glutathione; Methemoglobin; Oxidation-Reduction; Penicillamine; Pharmacology; Research; Sulfhydryl Compounds; Sulfites

1963
EFFECT OF CYSTAMINE AND CYSTEAMINE ON X-IRRADIATED HAIR FOLLICLES.
    International journal of radiation biology and related studies in physics, chemistry, and medicine, 1963, Volume: 7

    Topics: Animals; Cell Division; Cystamine; Cysteamine; Hair; Hair Follicle; Radiation Injuries; Radiation Injuries, Experimental; Rats; Research; Skin

1963
[ANALYSIS OF THE ACTION OF RADIOPROTECTIVE AGENTS WITH REGARD TO THEIR PRACTICAL USE].
    Meditsinskaia radiologiia, 1963, Volume: 8

    Topics: Animals; beta-Aminoethyl Isothiourea; Cystamine; Cysteamine; Mice; Pharmacology; Radiation-Protective Agents; Research

1963
PROTECTION AGAINST NITROGEN MUSTARD BY CYSTEINE AND RELATED SUBSTANCES, INVESTIGATED USING (3H)METHYL-DI-(2-CHLOROETHYL) AMINE.
    Biochemical pharmacology, 1963, Volume: 12

    Topics: Amines; Cystamine; Cysteamine; Cysteine; Mechlorethamine; Mice; Penicillamine; Pharmacology; Radiation-Protective Agents; Research; Tritium

1963
FACTORS AFFECTING THE IN VITRO INACTIVATION OF ALDOLASE BY X-RAYS.
    International journal of radiation biology and related studies in physics, chemistry, and medicine, 1963, Volume: 7

    Topics: beta-Aminoethyl Isothiourea; Biochemical Phenomena; Biochemistry; Cystamine; Cysteamine; Fructose-Bisphosphate Aldolase; Glutathione; In Vitro Techniques; Pharmacology; Radiation Effects; Research; Urea; X-Rays

1963
[REPRODUCTIVE CAPACITY OF MICE IRRADIATED WITH HIGH ENERGY PROTONS FOLLOWING ADMINISTRATION OF CHEMICAL PROTECTIVE SUBSTANCES].
    Radiobiologiia, 1963, Volume: 3

    Topics: Animals; beta-Aminoethyl Isothiourea; Chromosome Aberrations; Cystamine; Cysteamine; Hydroxylamines; Infertility; Infertility, Male; Male; Mice; Protons; Radiation Genetics; Radiation Injuries; Radiation Injuries, Experimental; Radiation-Protective Agents; Research; Spermatozoa

1963
[PROTECTIVE EFFECT OF MERCAMINE AND CYSTAMINE IN REPEATED IRRADIATIONS].
    Meditsinskii zhurnal Uzbekistana, 1963, Volume: 8

    Topics: Animals; Cystamine; Cysteamine; Cystine; Growth; Leukocyte Count; Mice; Radiation Effects; Radiation Injuries; Radiation Injuries, Experimental; Rats; Research

1963
[EFFECT OF SOME RADIO-PROTECTIVE AGENTS ON THE ENZYME SYSTEM OF LIVER MICROSOMES DEGRADING HEXOBARBITAL].
    Biochemical pharmacology, 1964, Volume: 13

    Topics: Cystamine; Cysteamine; Glucosephosphate Dehydrogenase; Hexobarbital; Hexosephosphates; Histamine; Liver; Metabolism; Microsomes, Liver; NADP; Pharmacology; Radiation-Protective Agents; Rats; Research; Serotonin

1964
STUDIES ON THE GROWTH-INHIBITING AND RADIOPROTECTIVE EFFECT OF CYSTAMINE, CYSTEAMINE, AND AET ON MAMMALIAN CELLS IN TISSUE CULTURE.
    Radiation research, 1964, Volume: 21

    Topics: Animals; beta-Aminoethyl Isothiourea; Cell Division; Cystamine; Cysteamine; Mice; Radiation-Protective Agents; Research; Research Design; Sulfur Isotopes; Tissue Culture Techniques; Toxicology

1964
[CHANGE OF THE OXYGEN REQUIREMENT OF ERYTHROCYTES UNDER THE INFLUENCE OF CYSTAMINE].
    Radiobiologiia, 1964, Volume: 4

    Topics: Animals; Birds; Cystamine; Cysteamine; Dogs; Erythrocytes; Metabolism; Oximetry; Oxygen; Pharmacology; Radiation-Protective Agents; Research

1964
[FORMATION OF CYSTEAMINE FROM CYSTAMINE IRRADIATED WITH X-RAYS IN THE PRESENCE OF REACTIVE THIOL GROUPS].
    Rendiconti - Istituto superiore di sanita, 1964, Volume: 27

    Topics: Cystamine; Cysteamine; Radiation Effects; Sulfhydryl Compounds; X-Rays

1964
[ON SOME GENERAL PHARMACODYNAMIC EFFECTS OF CYSTAMINE IN THE RAT].
    Archives internationales de pharmacodynamie et de therapie, 1964, Apr-01, Volume: 148

    Topics: Adrenalectomy; Anti-Allergic Agents; Antihypertensive Agents; Bis-Trimethylammonium Compounds; Blood Pressure; Blood Pressure Determination; Bradykinin; Cystamine; Cysteamine; Dextrans; Edema; Guanethidine; Histamine H1 Antagonists; Histamine Release; Lysergic Acid Diethylamide; Norepinephrine; p-Methoxy-N-methylphenethylamine; Pertussis Vaccine; Pharmacology; Phentolamine; Promethazine; Rats; Research; Reserpine; Toxicology

1964
IMPORTANCE FOR RADIO-PROTECTION OF THE REACTION OF CELL TO SULPHYDRYL AND DISULPHIDE COMPOUNDS.
    Nature, 1964, Jul-11, Volume: 203

    Topics: Cystamine; Cysteamine; Disulfides; Glutathione; Guanidines; Injections, Intraperitoneal; Mercaptoethanol; Metabolism; Nitrogen Mustard Compounds; Oxidoreductases; Penicillamine; Peroxidases; Radiation Injuries; Radiation Injuries, Experimental; Radiation Protection; Radiation-Protective Agents; Research; Spleen; Sulfhydryl Compounds; Sulfides

1964
[ON THE SUBJECT OF PROTECTIVE ACTION OF CYSTEAMINE AND CYSTAMINE IN IRRADIATED RATS].
    Journal belge de radiologie, 1964, Volume: 47

    Topics: Animals; Cystamine; Cysteamine; Pharmacology; Radiation Injuries; Radiation Injuries, Experimental; Radiation-Protective Agents; Rats; Research; Toxicology

1964
[MODIFICATION OF ANTI-TUMOR IMMUNITY AFTER TOTAL-BODY IRRADIATION. INFLUENCE OF CYSTAMINE].
    Comptes rendus des seances de la Societe de biologie et de ses filiales, 1964, Volume: 158

    Topics: Animals; Cystamine; Cysteamine; Mice; Neoplasms; Pharmacology; Radiation Effects; Research; Sarcoma; Sarcoma, Experimental

1964
[EFFECT OF CYSTAMINE AND CYSTEAMINE ON THE DEVELOPMENT OF AN EHRLICH TUMOR IRRADIATED IN VITRO].
    Comptes rendus des seances de la Societe de biologie et de ses filiales, 1964, Volume: 158

    Topics: Animals; Carcinoma; Carcinoma, Ehrlich Tumor; Cystamine; Cysteamine; In Vitro Techniques; Neoplasms; Pharmacology; Radiation Effects; Research

1964
THYROIDAL IODIDE TRANSPORT. VII. ACUTE STIMULATION OF THYROIDAL IODIDE CONCENTRATING ABILITY BY CYSTAMINE AND CYSTEAMINE.
    Endocrinology, 1965, Volume: 76

    Topics: Adenosine Triphosphatases; Antithyroid Agents; Cystamine; Cysteamine; Imidazoles; Iodides; Iodine; Iodine Isotopes; Kidney; Kinetics; Metabolism; Ouabain; Pharmacology; Pituitary Gland; Potassium; Rats; Research; Sodium; Thiouracil; Thyroid Gland

1965
[RADIOPROTECTIVE ACTION OF CYSTEAMINE AND CYSTAMINE IN MICE AS A FUNCTION OF THE PERIOD OF TIME BETWEEN INJECTION OF THE PROTECTOR AND THE START OF X-RAY IRRADIATION].
    Archives internationales de pharmacodynamie et de therapie, 1965, Volume: 153

    Topics: Animals; Cystamine; Cysteamine; Mice; Pharmacology; Radiation Injuries; Radiation Injuries, Experimental; Radiation-Protective Agents; Research; X-Rays

1965
ISOLATION OF SH-CONTAINING DNA-NUCLEOPROTEINS BY CHROMATOGRAPHY ON ORGANOMERCURIAL POLYSACCHARIDE.
    Biochimica et biophysica acta, 1965, Apr-12, Volume: 100

    Topics: Ammonium Compounds; Chemical Phenomena; Chemistry; Chromatography; Cystamine; Cysteamine; DNA; Edetic Acid; Liver; Metabolism; Nucleoproteins; Polysaccharides; Quaternary Ammonium Compounds; Rats; Research; Sulfhydryl Compounds; Sulfur Isotopes

1965
(DEGRADATION OF CYSTALDIMINE, THE PRODUCT OF OXIDATIVE DEAMINATION OF CYSTAMINE.)
    Biochimica et biophysica acta, 1965, Apr-12, Volume: 100

    Topics: Amine Oxidase (Copper-Containing); Animals; Autoradiography; Chromatography; Cystamine; Cysteamine; Deamination; Imines; Kidney; Oxidation-Reduction; Research; Sulfur Isotopes; Swine

1965
[RELATION BETWEEN RADIOPROTECTION AND HYPOTHERMIA INDUCED BY VARIOUS CHEMICAL SUBSTANCES)].
    International journal of radiation biology and related studies in physics, chemistry, and medicine, 1965, Volume: 9

    Topics: Animals; Chlorpromazine; Cyanides; Cystamine; Cysteamine; Cysteine; Fluoroacetates; Hypothermia; Injections; Injections, Intraperitoneal; Mice; Pharmacology; Radiation Protection; Radiation-Protective Agents; Research; Reserpine; Serotonin

1965
[ACTION OF CYSTAMINE AND CYSTEAMINE ON THE OXYGEN CONSUMPTION AND COUPLED OXYDATIVE PHOSPHORYLATION OF THE LIVER MITOCHONDRIA OF RATS].
    International journal of radiation biology and related studies in physics, chemistry, and medicine, 1965, Volume: 9

    Topics: Cystamine; Cysteamine; Liver; Metabolism; Mitochondria; Mitochondria, Liver; Oxidative Phosphorylation; Oxygen Consumption; Pharmacology; Phosphorylation; Rats; Research

1965
[Effects of cystamine and of cysteamine on the development of alloxan diabetes].
    Archives internationales de pharmacodynamie et de therapie, 1955, Apr-01, Volume: 101, Issue:3

    Topics: Animals; Cystamine; Cysteamine; Diabetes Mellitus, Experimental; Ethylamines

1955
[Cysteamine and cystamine in the treatment of radiation sickness].
    Bruxelles medical, 1955, Apr-24, Volume: 35, Issue:17

    Topics: Cystamine; Cysteamine; Ethylamines; Humans; Radiation Injuries; X-Rays

1955
[First results on the use of 2-mercaptoethylamine and cystamine in the prevention of radiation sickness].
    Giornale di clinica medica, 1955, Volume: 36, Issue:1

    Topics: Biomedical Research; Cystamine; Cysteamine; Ethylamines; Humans; Radiation Injuries

1955
[Action of cysteamine and cystamine on anaerobic glycolysis and tissue oxygen consumption].
    Comptes rendus des seances de la Societe de biologie et de ses filiales, 1960, Volume: 154

    Topics: Carbohydrate Metabolism; Carbohydrates; Cystamine; Cysteamine; Glycolysis; Mercaptoethylamines; Metabolism; Oxygen Consumption

1960
[On the radioprotective effect of a cysteamine-cystamine-glutathione combination. Anatomofunctional research on the bone marrow and on the peripheral blood].
    Radiobiologia, radioterapia, e fisica medica, 1960, Volume: 15

    Topics: Bone Marrow; Bone Marrow Diseases; Cystamine; Cysteamine; Glutathione; Mercaptoethylamines; Neoplasms; Radiation Injuries; Radiation Protection; Research

1960
Vanin-1-/- mice exhibit a glutathione-mediated tissue resistance to oxidative stress.
    Molecular and cellular biology, 2004, Volume: 24, Issue:16

    Topics: Amidohydrolases; Animals; Apoptosis; Cell Adhesion Molecules; Cell Line; Cystamine; Cysteamine; Epithelial Cells; Gamma Rays; Gene Expression Regulation, Enzymologic; Glutamate-Cysteine Ligase; Glutathione; GPI-Linked Proteins; Herbicides; Inflammation; Mice; Mice, Inbred BALB C; Mice, Knockout; Oxidative Stress; Paraquat; Promoter Regions, Genetic; Radiation-Protective Agents; Reactive Oxygen Species; Thymus Gland

2004
Different inhibition characteristics of intracellular transglutaminase activity by cystamine and cysteamine.
    Experimental & molecular medicine, 2004, Dec-31, Volume: 36, Issue:6

    Topics: Cell Line, Tumor; Cystamine; Cysteamine; Enzyme Inhibitors; Humans; Transglutaminases

2004
Treatment of YAC128 mice and their wild-type littermates with cystamine does not lead to its accumulation in plasma or brain: implications for the treatment of Huntington disease.
    Journal of neurochemistry, 2005, Volume: 94, Issue:4

    Topics: Animals; Brain; Chromatography, High Pressure Liquid; Colorimetry; Cystamine; Cysteamine; Female; Glutathione; Huntington Disease; Male; Mice; Mice, Transgenic; Taurine; Time Factors

2005
Cystamine and cysteamine increase brain levels of BDNF in Huntington disease via HSJ1b and transglutaminase.
    The Journal of clinical investigation, 2006, Volume: 116, Issue:5

    Topics: Aged; Animals; Brain; Brain-Derived Neurotrophic Factor; Caenorhabditis elegans; Cystamine; Cysteamine; HSP40 Heat-Shock Proteins; Humans; Huntington Disease; Macaca; Mice; Mice, Transgenic; Middle Aged; Molecular Chaperones; Neuroprotective Agents; Rats; Rats, Sprague-Dawley; Transglutaminases

2006
Cystamine and cysteamine prevent 3-NP-induced mitochondrial depolarization of Huntington's disease knock-in striatal cells.
    The European journal of neuroscience, 2006, Volume: 23, Issue:7

    Topics: Animals; Cell Death; Cell Line; Clone Cells; Corpus Striatum; Cystamine; Cysteamine; Electron Transport Complex II; Glutathione; Huntingtin Protein; Membrane Potentials; Mice; Mice, Mutant Strains; Mitochondria; Mitochondrial Membranes; Mutation; Nerve Tissue Proteins; Nitro Compounds; Nuclear Proteins; Propionates

2006
Drug shows potential for treatment of Huntington's disease.
    The Lancet. Neurology, 2006, Volume: 5, Issue:6

    Topics: Brain-Derived Neurotrophic Factor; Cell Death; Cystamine; Cysteamine; Enzyme Inhibitors; Humans; Huntington Disease

2006
Stable supply of large amounts of human Fab from the inclusion bodies in E. coli.
    Journal of biochemistry, 2007, Volume: 141, Issue:5

    Topics: Animals; Chromatography, High Pressure Liquid; Chromatography, Ion Exchange; Cloning, Molecular; Cystamine; Cysteamine; Dialysis; Electrophoresis, Polyacrylamide Gel; Escherichia coli; Humans; Immunoglobulin Fab Fragments; Immunoglobulin G; Immunoglobulin Heavy Chains; Inclusion Bodies; Protein Folding; Rabbits

2007
Differential gene expression in mouse liver associated with the hepatoprotective effect of clofibrate.
    Toxicology and applied pharmacology, 2007, Jul-15, Volume: 222, Issue:2

    Topics: Acetaminophen; Acyl-CoA Oxidase; Amidohydrolases; Animals; Anticholesteremic Agents; Cell Adhesion Molecules; Chemical and Drug Induced Liver Injury; Clofibrate; Cluster Analysis; Cystamine; Cysteamine; Enoyl-CoA Hydratase; Gene Expression Profiling; GPI-Linked Proteins; Liver; Liver Diseases; Malate Dehydrogenase; Male; Mice; Mice, Inbred Strains; Mice, Knockout; Oligonucleotide Array Sequence Analysis; Pantetheine; Pantothenic Acid; Peroxisome Proliferators; PPAR alpha; Proteasome Endopeptidase Complex; Reverse Transcriptase Polymerase Chain Reaction

2007
Drastically decreased reactivity of thiols and disulfides complexed by cucurbit[6]uril.
    Organic letters, 2008, Sep-04, Volume: 10, Issue:17

    Topics: Bridged-Ring Compounds; Cystamine; Cysteamine; Disulfides; Imidazoles; Kinetics; Magnetic Resonance Spectroscopy; Models, Molecular; Oxidation-Reduction; Sulfhydryl Compounds; Thermodynamics

2008
Measurement of sulfur-containing compounds involved in the metabolism and transport of cysteamine and cystamine. Regional differences in cerebral metabolism.
    Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2009, Oct-15, Volume: 877, Issue:28

    Topics: Animals; Biological Transport; Cerebrum; Chromatography, High Pressure Liquid; Cystamine; Cysteamine; Male; Oxidation-Reduction; Rats; Rats, Sprague-Dawley; Sulfur Compounds

2009
Cystamine metabolism and brain transport properties: clinical implications for neurodegenerative diseases.
    Journal of neurochemistry, 2010, Volume: 114, Issue:6

    Topics: Animals; Biological Transport; Blood-Brain Barrier; Brain; Cystamine; Cysteamine; Male; Mice; Mice, Inbred C57BL; Neuroprotective Agents; Taurine

2010
Selenium and sulfur in exchange reactions: a comparative study.
    The Journal of organic chemistry, 2010, Oct-01, Volume: 75, Issue:19

    Topics: Cystamine; Cysteamine; Molecular Structure; Selenium; Sulfur

2010
New mechanistic explanation for the localization of ulcers in the rat duodenum: role of iron and selective uptake of cysteamine.
    Archives of biochemistry and biophysics, 2012, Sep-01, Volume: 525, Issue:1

    Topics: Animals; Biological Transport; Caco-2 Cells; Cystamine; Cysteamine; Deferoxamine; Duodenal Ulcer; Duodenum; Female; Gene Expression Regulation; Humans; Intestinal Absorption; Intestinal Mucosa; Intracellular Space; Iron; Iron Chelating Agents; Mice; Organ Specificity; Organic Cation Transport Proteins; Rats; Reactive Oxygen Species; Sodium

2012
Identification of the oxidation products of cysteamine and cystamine by CE-MS interfaced by a noncommercial electrospray ionization source.
    Journal of separation science, 2012, Volume: 35, Issue:10-11

    Topics: Cystamine; Cysteamine; Oxidation-Reduction; Spectrometry, Mass, Electrospray Ionization

2012
Three salts from the reactions of cysteamine and cystamine with L-(+)-tartaric acid.
    Acta crystallographica. Section C, Crystal structure communications, 2013, Volume: 69, Issue:Pt 6

    Topics: Crystallography, X-Ray; Cystamine; Cysteamine; Hydrogen Bonding; Models, Molecular; Molecular Structure; Salts; Tartrates

2013
Targeting microparticle biogenesis: a novel approach to the circumvention of cancer multidrug resistance.
    Current cancer drug targets, 2015, Volume: 15, Issue:3

    Topics: Acrylates; Amides; Antineoplastic Agents; Breast Neoplasms; Calcimycin; Cell Line, Tumor; Cell-Derived Microparticles; Cystamine; Cysteamine; Drug Resistance, Neoplasm; Female; Humans; Molecular Targeted Therapy; Oligopeptides; Pantetheine; Pyridines; Verapamil

2015
Cystamine/cysteamine rescues the dopaminergic system and shows neurorestorative properties in an animal model of Parkinson's disease.
    Neurobiology of disease, 2015, Volume: 82

    Topics: Animals; Antiparkinson Agents; Astrocytes; Cell Line; Cells, Cultured; Corpus Striatum; Cystamine; Cysteamine; Disease Models, Animal; Dopaminergic Neurons; Indans; Lipopolysaccharides; Male; Mice, Inbred C57BL; Neurites; Neuroprotective Agents; Oxidopamine; Parkinsonian Disorders

2015
Cysteamine, an Endogenous Aminothiol, and Cystamine, the Disulfide Product of Oxidation, Increase Pseudomonas aeruginosa Sensitivity to Reactive Oxygen and Nitrogen Species and Potentiate Therapeutic Antibiotics against Bacterial Infection.
    Infection and immunity, 2018, Volume: 86, Issue:6

    Topics: Animals; Anti-Bacterial Agents; Cystamine; Cysteamine; Drug Resistance, Bacterial; Male; Mice; Microbial Sensitivity Tests; Pseudomonas aeruginosa; Pseudomonas Infections; Reactive Nitrogen Species; Reactive Oxygen Species

2018
Base-Sequence-Independent Efficient Redox Switching of Self-Assembled DNA Nanocages.
    Chembiochem : a European journal of chemical biology, 2019, 11-04, Volume: 20, Issue:21

    Topics: Base Sequence; Cystamine; Cysteamine; DNA; Electrophoresis; Microscopy, Atomic Force; Models, Chemical; Molecular Structure; Nanostructures; Nanotechnology; Nucleic Acid Conformation; Oxidation-Reduction

2019
Inhibition of Transglutaminase 2 as a Potential Host-Directed Therapy Against
    Frontiers in immunology, 2019, Volume: 10

    Topics: Amikacin; Anti-Bacterial Agents; Antitubercular Agents; Autophagy; Cystamine; Cysteamine; DNA Replication; Drug Synergism; Granuloma; GTP-Binding Proteins; Humans; Macrophages; Mycobacterium tuberculosis; Protein Glutamine gamma Glutamyltransferase 2; THP-1 Cells; Transglutaminases; Tuberculosis, Multidrug-Resistant

2019
Cysteamine with In Vitro Antiviral Activity and Immunomodulatory Effects Has the Potential to Be a Repurposing Drug Candidate for COVID-19 Therapy.
    Cells, 2021, 12-24, Volume: 11, Issue:1

    Topics: Aged; Animals; Antiviral Agents; Cell Line, Tumor; Chlorocebus aethiops; COVID-19; COVID-19 Drug Treatment; Cystamine; Cysteamine; Cystine Depleting Agents; Drug Repositioning; Female; Humans; Immunomodulating Agents; Male; Middle Aged; RNA, Viral; SARS-CoV-2; Vero Cells; Virus Replication

2021
Cysteamine/Cystamine Exert Anti-
    International journal of molecular sciences, 2023, Jan-07, Volume: 24, Issue:2

    Topics: Amikacin; Anti-Bacterial Agents; Cystamine; Cysteamine; Humans; Leukocytes, Mononuclear; Microbial Sensitivity Tests; Mycobacterium abscessus; Mycobacterium Infections, Nontuberculous

2023