cystathionine has been researched along with pyridoxal phosphate in 49 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 26 (53.06) | 18.7374 |
| 1990's | 6 (12.24) | 18.2507 |
| 2000's | 5 (10.20) | 29.6817 |
| 2010's | 12 (24.49) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Rych, K | 1 |
| Beratis, NG; Gaull, GE; Gillam, BM; Pascal, TA; Tallan, HH | 1 |
| Benevenga, NJ; Everett, GB; Mitchell, AD | 1 |
| Marcotte, P; Walsh, C | 1 |
| Brown, RR; Leklem, JE; Linkswiler, HM; Rose, DP | 2 |
| Beratis, NG; Gaull, GE; Gillam, BM; Hirschhorn, K; Pascal, TA; Tallan, HH | 1 |
| Morino, Y; Tanase, S | 1 |
| Chatagner, F; de Billy, G; Ipaktchi, M; Lefauconnier, JM; Portemer, C | 1 |
| Churchich, JE; Oh, KJ | 1 |
| Barboza, V; Fernandez, E; Pulgar, J | 1 |
| Florentiev, VL; Goryachenkova, EV; Polyakova, LA; Yefremova, LL | 1 |
| Heinonen, K | 1 |
| Churchich, JE; O, KJ | 1 |
| Chatagner, F; Garcia-Peregrin, E | 1 |
| Dunathan, HC | 1 |
| Churchich, JE; Dupourque, D | 1 |
| Churchich, JE | 1 |
| Flavin, M; Posner, BI | 2 |
| Costa, MT; Giarnieri, D; Wolf, AM | 1 |
| Endres, W; Friedrich, B; Rasshofer, R; Shin, YS | 1 |
| Dwivedi, CM; Ragin, RC; Uren, JR | 1 |
| Morzycka, E; Paszewski, A | 1 |
| Douce, R; Droux, M; Ravanel, S | 2 |
| Bukovska, G; Kery, V; Kraus, JP | 1 |
| Cole, DE; Donovan, SM; Howell, DS; Mahuren, JD; Massé, PG; Yamauchi, M; Ziv, I | 1 |
| Bai, SC; Morris, JG; Rogers, QR; Sampson, DA; Wong, DL | 1 |
| Finkelstein, JD | 1 |
| Dunn, MF; Jhee, KH; McPhie, P; Miles, EW; Niks, D | 1 |
| GORIACHENKOVA, EV | 1 |
| FLAVIN, M; SLAUGHTER, C | 1 |
| FLAVIN, M; SEGAL, A | 1 |
| Aitken, SM; Kirsch, JF | 1 |
| Hustad, S; Midttun, Ø; Schneede, J; Ueland, PM; Vollset, SE | 1 |
| Inada, A; Ozaki, S; Sada, K | 1 |
| Chua, JH; Deng, LW; Huang, S; Moore, PK; Sivaraman, J; Tan, CH; Yew, WS | 1 |
| Coats, B; Gregory, JF; Lamers, Y; Quinlivan, EP; Ralat, M; Stacpoole, PW | 1 |
| Paietta, JV; Reveal, BS | 1 |
| Aitken, SM; Jaworski, AF; Lodha, PH; Manders, AL | 1 |
| Bandyopadhyay, N; Chi, YY; da Silva, V; Gregory, JF; Hove, N; Jones, DP; Kahveci, T; Kim, S; Lamers, Y; Lee, K; Muller, KE; Newgard, CB; Park, Y; Ranka, S; Stacpoole, PW; Stevens, RD | 1 |
| Chi, YY; Coats, B; da Silva, VR; Garrett, TJ; Gregory, JF; Lamers, Y; Midttun, Ø; Muller, KE; Percival, SS; Quinlivan, EP; Ralat, MA; Rios-Avila, L; Shankar, MN; Stacpoole, PW; Ueland, PM | 1 |
| Aliani, M; House, JD; Mayengbam, S; Raposo, S | 1 |
| Chi, YY; Coats, B; Gregory, JF; Midttun, Ø; Ralat, M; Rios-Avila, L; Stacpoole, PW; Ueland, PM | 1 |
| Cabiscol, E; Fernández-Nogales, M; Ferrer, I; Lucas, JJ; Rodríguez-Colman, MJ; Sorolla, MA; Vall-Llaura, N; Vived, C | 1 |
| Allegrini, A; Astegno, A; Dominici, P; La Verde, V | 1 |
| Stone, E; Yan, W; Zhang, YJ | 1 |
| Farias, DR; Franco-Sena, AB; Kac, G; Lamers, Y; Mujica-Coopman, MF; Vaz, JS | 1 |
3 review(s) available for cystathionine and pyridoxal phosphate
| Article | Year |
|---|---|
Stereochemical aspects of pyridoxal phosphate catalysis.
Topics: 5-Aminolevulinate Synthetase; Alanine Transaminase; Allosteric Regulation; Amino Acids; Aspartic Acid; Binding Sites; Carboxy-Lyases; Catalysis; Cystathionine; Glycine; Homoserine; Kinetics; Lyases; Models, Biological; Molecular Conformation; Protein Binding; Protein Conformation; Pyridoxal Phosphate; Schiff Bases; Serine; Structure-Activity Relationship; Threonine; Transaminases; Transferases | 1971 |
Pathways and regulation of homocysteine metabolism in mammals.
Topics: Animals; Cystathionine; Cystathionine beta-Synthase; Cystathionine gamma-Lyase; Cysteine; Heme; Homocysteine; Isoenzymes; Kinetics; Mammals; Methionine; Methionine Adenosyltransferase; Organ Specificity; Oxidation-Reduction; Pyridoxal Phosphate; S-Adenosylhomocysteine; S-Adenosylmethionine; Sulfur; Tetrahydrofolates | 2000 |
The enzymology of cystathionine biosynthesis: strategies for the control of substrate and reaction specificity.
Topics: Allosteric Regulation; Amino Acid Substitution; Binding Sites; Carbon-Oxygen Lyases; Catalysis; Catalytic Domain; Cystathionine; Cystathionine beta-Synthase; Dimerization; Enzyme Activation; Gene Expression Regulation, Enzymologic; Homocysteine; Kinetics; Oxidation-Reduction; Protein Structure, Tertiary; Pyridoxal Phosphate; Stereoisomerism; Substrate Specificity | 2005 |
3 trial(s) available for cystathionine and pyridoxal phosphate
| Article | Year |
|---|---|
Vitamin B6 requirements of women using oral contraceptives.
Topics: Adult; Alanine Transaminase; Aspartate Aminotransferases; Contraceptives, Oral; Contraceptives, Oral, Hormonal; Cystathionine; Female; Humans; Methionine; Nutritional Requirements; Pyridoxal Phosphate; Pyridoxic Acid; Pyridoxine; Tryptophan; Vitamin B 6 Deficiency | 1975 |
Moderate vitamin B-6 restriction does not alter postprandial methionine cycle rates of remethylation, transmethylation, and total transsulfuration but increases the fractional synthesis rate of cystathionine in healthy young men and women.
Topics: Adult; Breath Tests; Carbon Isotopes; Cystathionine; Deuterium; Diet; DNA Methylation; Female; Humans; Kinetics; Leucine; Male; Methionine; Methylation; Monocytes; Postprandial Period; Pyridoxal Phosphate; Reproducibility of Results; Severity of Illness Index; Vitamin B 6; Vitamin B 6 Deficiency; Young Adult | 2011 |
Metabolomic analysis reveals extended metabolic consequences of marginal vitamin B-6 deficiency in healthy human subjects.
Topics: Acetates; Adult; Amino Acids; Carnitine; Cystathionine; Female; Glutamic Acid; Glutamine; Humans; Ketoglutaric Acids; Male; Metabolomics; Proline; Pyridoxal Phosphate; Vitamin B 6; Vitamin B 6 Deficiency; Young Adult | 2013 |
43 other study(ies) available for cystathionine and pyridoxal phosphate
| Article | Year |
|---|---|
[Seesaw nystagmus: symptom of a biochemical disorder (author's transl)].
Topics: Adolescent; Amino Acid Metabolism, Inborn Errors; Cystathionine; Female; Humans; Male; Neurologic Manifestations; Nystagmus, Pathologic; Pyridoxal Phosphate | 1977 |
Cystathionase deficiency: evidence for genetic heterogeneity in primary cystathioninuria.
Topics: Amino Acid Metabolism, Inborn Errors; Animals; Binding Sites, Antibody; Binding, Competitive; Cell Line; Cystathionine; Cystathionine gamma-Lyase; Fetus; Haplorhini; Humans; Immune Sera; Immunodiffusion; Immunoelectrophoresis; In Vitro Techniques; Lyases; Pyridoxal Phosphate; Rats | 1978 |
Methionine transamination and catabolism in vitamin B-6 deficient rats.
Topics: Amination; Animals; Caseins; Cystathionine; Dietary Proteins; Liver; Male; Methionine; Oxidation-Reduction; Phosphatidylcholines; Pyridoxal Phosphate; Rats; Vitamin B 6 Deficiency | 1979 |
Active site-directed inactivation of cystathionine gamma-synthetase and glutamic pyruvic transaminase by propargylglycine.
Topics: Acetylene; Alanine Transaminase; Amino Acids; Animals; Cystathionine; Kinetics; Lyases; Myocardium; Pyridoxal Phosphate; Salmonella typhimurium; Swine; Time Factors | 1975 |
Vitamin B6-responsive and -unresponsive cystathioninuria: two variant molecular forms.
Topics: Amino Acid Metabolism, Inborn Errors; Cell Line; Cross Reactions; Cystathionine; Cystathionine gamma-Lyase; Dose-Response Relationship, Drug; Enzyme Activation; Humans; Lyases; Mutation; Pyridoxal Phosphate; Pyridoxine | 1975 |
Effects of oral contraceptives on tryptophan metabolism and vitamin B6 requirements in women.
Topics: Adult; Contraceptives, Oral; Cystathionine; Female; Humans; Kynurenine; Methionine; Pyridoxal Phosphate; Pyridoxine; Sex Factors; Tryptophan; Vitamin B 6 Deficiency | 1975 |
[Vitamin B6 dependency syndrome].
Topics: Amino Acid Metabolism, Inborn Errors; Aspartate Aminotransferases; Cystathionine; Homocystinuria; Humans; Hyperoxaluria; Ornithine; Pyridoxal Phosphate; Pyridoxine | 1992 |
Redistribution of pyridoxal phosphate in the male rat liver as a result of repeated injections of hydrocortisone.
Topics: Alanine Transaminase; Animals; Aspartic Acid; Carboxy-Lyases; Cystathionine; Cysteine; Dose-Response Relationship, Drug; Homocysteine; Homoserine; Hydro-Lyases; Hydrocortisone; L-Serine Dehydratase; Liver; Lyases; Male; Pyridoxal Phosphate; Rats; Seasons; Serine; Time Factors; Tyrosine Transaminase | 1973 |
Fluorescence studies on the interaction between pyridoxal phosphate enzymes.
Topics: Animals; Apoenzymes; Aspartate Aminotransferases; Binding Sites; Chromatography, Ion Exchange; Cystathionine; Cytoplasm; Electrophoresis, Starch Gel; Hydrogen-Ion Concentration; Kinetics; Lyases; Macromolecular Substances; Mathematics; Myocardium; Protein Binding; Protein Conformation; Pyridoxal Phosphate; Spectrometry, Fluorescence; Swine; Time Factors | 1974 |
Kinetic characteristics of cisteine desulphydrase in the liver and pancreas of different biological species.
Topics: Animals; Chickens; Cystathionine; Cysteine; Dogs; Fishes; Homocysteine; In Vitro Techniques; Kinetics; Liver; Lyases; Mice; Pancreas; Pyridoxal Phosphate; Pyruvates; Rats; Species Specificity; Swine | 1973 |
Interaction of pyridoxal phosphate analogues with apoenzymes of gamma-cystathionase and serine sulphhydrase.
Topics: Animals; Apoproteins; Binding Sites; Borohydrides; Chickens; Circular Dichroism; Cystathionine; Homocysteine; Hydro-Lyases; Hydrogen Sulfide; Kinetics; Liver; Lyases; Methylation; Penicillamine; Protein Binding; Pyridoxal Phosphate; Rats; Serine; Spectrophotometry; Spectrophotometry, Ultraviolet; Structure-Activity Relationship | 1973 |
Studies on cystathionase activity in rat liver and brain during development. Effects of hormones and amino acids in vivo.
Topics: Animals; Animals, Newborn; Brain; Cystathionine; Female; Fetus; Homoserine; Liver; Lyases; Methionine; Pregnancy; Pyridoxal Phosphate; Rats; Thyroxine; Time Factors; Triamcinolone | 1973 |
Binding of pyridoxal 5-phosphate to cystathionase.
Topics: Animals; Apoproteins; Binding Sites; Catalysis; Cystathionine; Dialysis; Homoserine; Liver; Lyases; Lysine; Macromolecular Substances; Mathematics; Models, Chemical; Protein Binding; Pyridoxal Phosphate; Rats; Spectrometry, Fluorescence; Spectrophotometry | 1973 |
Studies on the inactivation of rat liver cystathionase.
Topics: Animals; Cystathionine; Female; Homoserine; Hydrogen-Ion Concentration; Kinetics; Liver; Lyases; Pyridoxal Phosphate; Rats; Subcellular Fractions; Temperature; Time Factors; Ultracentrifugation | 1974 |
Dissociation of cystathionase.
Topics: Animals; Chemical Phenomena; Chemistry; Chromatography, Gel; Cystathionine; Detergents; Electrophoresis; Electrophoresis, Disc; Hydro-Lyases; Liver; Macromolecular Substances; Mathematics; Molecular Weight; Pyridoxal Phosphate; Rats; Scattering, Radiation; Sulfhydryl Compounds; Sulfuric Acids; Ultracentrifugation | 1972 |
Interactions between cystathionase and aspartate aminotransferase.
Topics: Animals; Apoproteins; Aspartate Aminotransferases; Binding Sites; Centrifugation, Density Gradient; Chemical Phenomena; Chemistry; Circular Dichroism; Cystathionine; Fluorescence; Homoserine; Hydro-Lyases; Hydrogen-Ion Concentration; Light; Liver; Macromolecular Substances; Myocardium; Pyridoxal Phosphate; Rats; Scattering, Radiation; Spectrophotometry; Swine | 1972 |
Cystathionine -synthase. Studies of hydrogen exchange reactions.
Topics: Alanine; Aminobutyrates; Catalysis; Chemical Phenomena; Chemistry; Cystathionine; Cysteine; Deuterium; Homoserine; Kinetics; Lyases; Magnetic Resonance Spectroscopy; Pyridoxal Phosphate; Salmonella; Serine; Succinates; Tritium | 1972 |
Cystathionine -synthase. The nature of intramolecular proton shifts in the elimination reaction.
Topics: Aluminum; Catalysis; Chemical Phenomena; Chemistry; Cystathionine; Deuterium; Homoserine; Isomerism; Isotope Labeling; Kinetics; Lyases; Magnetic Resonance Spectroscopy; Mass Spectrometry; Molecular Conformation; Optical Rotatory Dispersion; Protons; Pyridoxal; Pyridoxal Phosphate; Salmonella; Succinates; Sulfates | 1972 |
Cleavage of cystine by cystathionase.
Topics: Ammonia; Animals; Catalysis; Chromatography, Gel; Cystathionine; Cysteine; Cystine; Enzyme Activation; Homoserine; Hydro-Lyases; Hydrogen Sulfide; Kinetics; Liver; Oxygen; Pyridoxal Phosphate; Pyruvates; Rats; Spectrophotometry, Ultraviolet; Stereoisomerism; Sulfhydryl Compounds | 1972 |
Pyridoxal-5'-phosphate determination by a sensitive micromethod in human blood, urine and tissues; its relation to cystathioninuria in neuroblastoma and biliary atresia.
Topics: Adolescent; Adult; Bile Ducts; Brain Chemistry; Child; Child, Preschool; Cystathionine; Female; Fetus; Humans; Infant; Infant, Newborn; Kidney; Liver; Middle Aged; Neuroblastoma; Pregnancy; Pyridoxal Phosphate; Spleen | 1983 |
Cloning, purification, and characterization of beta-cystathionase from Escherichia coli.
Topics: Amino Acids; Cloning, Molecular; Cystathionine; Escherichia coli; Homocysteine; Kinetics; Lyases; Molecular Weight; Plasmids; Pyridoxal Phosphate | 1982 |
Cysteine and homocysteine synthesis in Saccharomycopsis lipolytica; identification and characterization of two cysteine synthases.
Topics: Ascomycota; Carbon-Oxygen Lyases; Cystathionine; Cystathionine gamma-Lyase; Cysteine; Cysteine Synthase; Homocysteine; Lyases; Multienzyme Complexes; Mutation; Pyridoxal Phosphate; Saccharomyces cerevisiae Proteins; Saccharomycopsis; Substrate Specificity | 1982 |
Methionine biosynthesis in higher plants. I. Purification and characterization of cystathionine gamma-synthase from spinach chloroplasts.
Topics: Alkynes; Carbon-Oxygen Lyases; Carbon-Sulfur Lyases; Cell Compartmentation; Chloroplasts; Cystathionine; Glycine; Homocysteine; Homoserine; Kinetics; Lyases; Methionine; Molecular Weight; Pargyline; Plant Leaves; Protein Conformation; Pyridoxal Phosphate; Spectrophotometry; Spinacia oleracea | 1995 |
Methionine biosynthesis in higher plants. II. Purification and characterization of cystathionine beta-lyase from spinach chloroplasts.
Topics: Aminobutyrates; Cell Compartmentation; Chloroplasts; Cystathionine; Homocysteine; Kinetics; Lyases; Methionine; Plant Leaves; Pyridoxal Phosphate; Pyruvates; Pyruvic Acid; Spectrophotometry; Spinacia oleracea | 1995 |
Transsulfuration depends on heme in addition to pyridoxal 5'-phosphate. Cystathionine beta-synthase is a heme protein.
Topics: Animals; Cystathionine; Cystathionine beta-Synthase; Escherichia coli; Heme; Hemeproteins; Homocysteine; Humans; Kinetics; Liver; Pyridoxal Phosphate; Rats; Recombinant Proteins; Serine; Spectrophotometry; Sulfur | 1994 |
A cartilage matrix deficiency experimentally induced by vitamin B6 deficiency.
Topics: Animals; Body Weight; Cartilage, Articular; Chickens; Cystathionine; Erythrocytes; Insulin-Like Growth Factor Binding Proteins; Insulin-Like Growth Factor I; Male; Osteoarthritis; Proteoglycans; Pyridoxal Phosphate; Pyridoxine; Sulfates; Synovial Fluid; Vitamin B 6 Deficiency | 1998 |
Vitamin B-6 deficiency and level of dietary protein affect hepatic tyrosine aminotransferase activity in cats.
Topics: Animals; Cats; Circadian Rhythm; Cystathionine; Dietary Proteins; Food Deprivation; Liver; Pyridoxal Phosphate; Pyridoxamine; Pyridoxine; Rats; Rats, Sprague-Dawley; Tyrosine; Tyrosine Transaminase; Vitamin B 6 Deficiency | 1998 |
Yeast cystathionine beta-synthase reacts with L-allothreonine, a non-natural substrate, and L-homocysteine to form a new amino acid, 3-methyl-L-cystathionine.
Topics: Circular Dichroism; Cystathionine; Cystathionine beta-Synthase; Homocysteine; Kinetics; Magnetic Resonance Spectroscopy; Pyridoxal Phosphate; Saccharomyces cerevisiae; Serine; Spectrophotometry; Substrate Specificity; Threonine | 2002 |
[Role of pyridoxal phosphate in enzymatic formation and splitting of cystathionine in transsulforization].
Topics: Coenzymes; Cystathionine; Pyridoxal Phosphate | 1952 |
CYSTATHIONINE CLEAVAGE ENZYMES OF NEUROSPORA.
Topics: Amino Acid Oxidoreductases; Amino Acids; Butyrates; Cystathionine; Cysteine; Homocysteine; Iodoacetates; L-Lactate Dehydrogenase; Maleates; Neurospora; Pyridoxal Phosphate; Pyruvates; Research; Serine; Sulfhydryl Compounds | 1964 |
PURIFICATION AND PROPERTIES OF THE CYSTATHIONINE GAMMA-CLEAVAGE ENZYME OF NEUROSPORA.
Topics: Amino Acid Oxidoreductases; Amino Acids; Butyrates; Cystathionine; Cysteine; Cystine; Enzyme Inhibitors; Ethers; Gamma Rays; Neurospora; Pyridoxal Phosphate; Research; Serine; Sulfides | 1964 |
Plasma vitamin B-6 forms and their relation to transsulfuration metabolites in a large, population-based study.
Topics: Cohort Studies; Cystathionine; Female; Genotype; Humans; Hydrolases; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Polymorphism, Single Nucleotide; Pyridoxal; Pyridoxal Phosphate; Pyridoxic Acid; Regression Analysis; Vitamin B 6 | 2007 |
Modulation of cystathionine beta-synthase activity by the Arg-51 and Arg-224 mutations.
Topics: Alanine; Amino Acid Sequence; Amino Acid Substitution; Catalysis; Cystathionine; Cystathionine beta-Synthase; Heme; Humans; Kinetics; Models, Molecular; Molecular Sequence Data; Molecular Structure; Mutation; Protein Structure, Secondary; Protein Structure, Tertiary; Pyridoxal Phosphate; Recombinant Proteins | 2008 |
Site-directed mutagenesis on human cystathionine-gamma-lyase reveals insights into the modulation of H2S production.
Topics: Amino Acid Substitution; Ammonia; Butyrates; Cystathionine; Cystathionine gamma-Lyase; Cysteine; Humans; Hydrogen Sulfide; Kinetics; Models, Molecular; Mutagenesis, Site-Directed; Mutant Proteins; Pyridoxal Phosphate; Pyruvic Acid | 2010 |
Analysis of the sulfur-regulated control of the cystathionine γ-lyase gene of Neurospora crassa.
Topics: Base Sequence; Binding Sites; Cloning, Molecular; Cystathionine; Cystathionine gamma-Lyase; Cysteine; Electrophoretic Mobility Shift Assay; Escherichia coli; Fungal Proteins; Gene Expression Regulation, Fungal; Gene Regulatory Networks; Molecular Sequence Data; Mutation; Neurospora crassa; Promoter Regions, Genetic; Protein Binding; Pyridoxal Phosphate; Recombinant Proteins; RNA, Messenger; Sulfur; Vesicular Transport Proteins | 2012 |
Exploration of the active site of Escherichia coli cystathionine γ-synthase.
Topics: Carbon-Oxygen Lyases; Catalytic Domain; Cystathionine; Escherichia coli; Escherichia coli Proteins; Kinetics; Models, Molecular; Mutagenesis, Site-Directed; Mutation; Pyridoxal Phosphate | 2012 |
Metabolite profile analysis reveals functional effects of 28-day vitamin B-6 restriction on one-carbon metabolism and tryptophan catabolic pathways in healthy men and women.
Topics: Adult; Biomarkers; Creatine; Cystathionine; Female; Humans; Inflammation; Kynurenic Acid; Kynurenine; Male; Multivariate Analysis; Postprandial Period; Pyridoxal Phosphate; Serine; Tryptophan; Vitamin B 6; Vitamin B 6 Deficiency; Young Adult | 2013 |
Oral exposure to the anti-pyridoxine compound 1-amino D-proline further perturbs homocysteine metabolism through the transsulfuration pathway in moderately vitamin B₆ deficient rats.
Topics: Animals; Asymptomatic Diseases; Biomarkers; Cystathionine; Cystathionine gamma-Lyase; Diet; Disease Models, Animal; Disease Progression; Flax; Homocysteine; Hyperhomocysteinemia; Liver; Male; Non-alcoholic Fatty Liver Disease; Proline; Pyridoxal Phosphate; Pyridoxine; Random Allocation; Rats, Sprague-Dawley; Seeds; Vitamin B 6; Vitamin B 6 Deficiency | 2015 |
Pyridoxine supplementation does not alter in vivo kinetics of one-carbon metabolism but modifies patterns of one-carbon and tryptophan metabolites in vitamin B-6-insufficient oral contraceptive users.
Topics: 3-Hydroxyanthranilic Acid; Adult; Biomarkers; Carbon; Contraceptives, Oral; Cystathionine; Dietary Supplements; Female; Glycine; Homocysteine; Humans; Kynurenine; Leucine; Methionine; Methylamines; Multivariate Analysis; Pyridoxal Phosphate; Pyridoxine; Serine; Tryptophan; Vitamin B 6 Deficiency; Young Adult | 2015 |
Impaired PLP-dependent metabolism in brain samples from Huntington disease patients and transgenic R6/1 mice.
Topics: Adult; Aged; Animals; Cerebral Cortex; Corpus Striatum; Cystathionine; Disease Models, Animal; Disease Progression; Female; Glutamic Acid; Humans; Huntington Disease; Male; Mice; Mice, Transgenic; Middle Aged; Oxidative Stress; Pyridoxal Phosphate; Young Adult | 2016 |
Characterization of C-S lyase from Lactobacillus delbrueckii subsp. bulgaricus ATCC BAA-365 and its potential role in food flavour applications.
Topics: Algorithms; Amino Acid Sequence; Bacterial Proteins; Carbon-Sulfur Lyases; Cystathionine; Cysteine; Electrophoresis, Polyacrylamide Gel; Enzyme Assays; Flavoring Agents; Hydrogen-Ion Concentration; Kinetics; Lactobacillus delbrueckii; Lyases; Models, Molecular; Protein Multimerization; Pyridoxal Phosphate; Recombinant Proteins; Spectrophotometry; Substrate Specificity; Sulfur Compounds | 2017 |
Structural Snapshots of an Engineered Cystathionine-γ-lyase Reveal the Critical Role of Electrostatic Interactions in the Active Site.
Topics: Amino Acid Substitution; Arginine; Biocatalysis; Carbon-Sulfur Lyases; Catalytic Domain; Cystathionine; Cystathionine gamma-Lyase; Cysteine; Enzyme Stability; Humans; Hydrogen Bonding; Hydrolysis; Methionine; Models, Molecular; Mutagenesis, Site-Directed; Osmolar Concentration; Protein Conformation; Protein Engineering; Pyridoxal Phosphate; Recombinant Proteins; Selenomethionine; Substrate Specificity | 2017 |
Maternal Plasma Pyridoxal 5'-Phosphate Concentration Is Inversely Associated with Plasma Cystathionine Concentration across All Trimesters in Healthy Pregnant Women.
Topics: Adult; Cystathionine; Female; Humans; Pregnancy; Pregnancy Trimesters; Prospective Studies; Pyridoxal Phosphate; Vitamin B 6; Young Adult | 2019 |