Page last updated: 2024-08-21

cyproterone acetate and metribolone

cyproterone acetate has been researched along with metribolone in 28 studies

Research

Studies (28)

TimeframeStudies, this research(%)All Research%
pre-199013 (46.43)18.7374
1990's7 (25.00)18.2507
2000's7 (25.00)29.6817
2010's1 (3.57)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Ernst, B; Lill, MA; Vedani, A; Winiger, F1
Bashirelahi, N; Ekiko, DB; Ganesan, S; Shida, K; Takahashi, E; Yamanaka, H; Young, JD1
Benítez, L; Centol, I; Déniz, A; Estévez, F; Fanjul, LF; González, J; Marrero, I; Quintana, J; Ruiz de Galarreta, CM1
Bartsch, W; Huang, JK; Voigt, KD1
Maruyama, S; Sato, S1
Hamilton, SR; Harnisch, E; Hogenschurz, R; Izbicki, JR; Izbicki, W; Kusche, J; Wambach, G1
Berns, EM; de Boer, W; Mulder, E1
Bolt, J; Brinkmann, AO; de Boer, W; Kuiper, GG; Mulder, E; van Steenbrugge, GJ1
Hackenberg, R; Hofmann, J; Hölzel, F; Schulz, KD1
Golsteyn, EJ; Lefebvre, YA; Michiel, TL1
Fanjul, LF; Hsueh, AJ; Meidan, R; Ruiz de Galarreta, CM1
Breedveld, DI; Brinkmann, AO; Lindh, LM; Mulder, E; Van Der Molen, HJ1
Brown, TR; Migeon, CJ; Rothwell, SW; Sultan, C1
Pierrepoint, CG; Younes, MA1
Itami, S; Kurata, S; Takayasu, S1
Govindan, MV; Koutsilieris, M; Pagé, N; Warriar, N1
Berrevoets, CA; Mulder, E; Veldscholte, J1
Kasson, BG; Li, YD1
Burnstein, KL; Cameron, DJ; Dai, JL; Maiorino, CA1
Bisht, D; Chakraborti, PK; Rana, S1
André, J; Foury, O; Joly-Pharaboz, MO; Nicolas, B1
Lumbroso, S; Moras, D; Nicolas, JC; Poujol, N; Sultan, C; Tahiri, B; Wurtz, JM1
Jones, GR; Lyng, FM; Rommerts, FF1
Georget, V; Paris, F; Servant, N; Sultan, C; Térouanne, B1
Auzou, G; Bourguet, W; Nirdé, P; Rabenoelina, F; Sultan, C; Terouanne, B1
Berrevoets, CA; Brinkmann, AO; Trapman, J; Umar, A1
Chang, CY; Elbi, C; Hager, GL; Hendarwanto, A; Klokk, TI; Kurys, P; Nagaich, AK; Saatcioglu, F; Slagsvold, T1
Jääskeläinen, T; Kauhanen, M; Makkonen, H; Palvimo, JJ1

Other Studies

28 other study(ies) available for cyproterone acetate and metribolone

ArticleYear
Impact of induced fit on ligand binding to the androgen receptor: a multidimensional QSAR study to predict endocrine-disrupting effects of environmental chemicals.
    Journal of medicinal chemistry, 2005, Sep-08, Volume: 48, Issue:18

    Topics: Benzhydryl Compounds; Binding Sites; Diethylstilbestrol; Endocrine System; Hydrocarbons, Chlorinated; Ligands; Models, Molecular; Molecular Conformation; Phenols; Phytoestrogens; Quantitative Structure-Activity Relationship; Receptors, Androgen; Testosterone; Thermodynamics; Xenobiotics

2005
Effect of 16 beta-ethyl-17 beta-hydroxy-4-estren-3-one (TSAA-291) on the binding of promegestone (R5020) and methyltrienolone (R1881) to hyperplastic and neoplastic human prostate.
    Journal of steroid biochemistry, 1986, Volume: 25, Issue:3

    Topics: Binding, Competitive; Centrifugation, Density Gradient; Cyproterone; Cyproterone Acetate; Dihydrotestosterone; Estrenes; Humans; Male; Mathematics; Metribolone; Nandrolone; Norpregnadienes; Promegestone; Prostatic Hyperplasia

1986
R1881 regulation of steroidogenesis in cultured testicular cells.
    Biochemistry international, 1989, Volume: 19, Issue:2

    Topics: 3-Hydroxysteroid Dehydrogenases; Aldehyde-Lyases; Androgen Antagonists; Animals; Cells, Cultured; Cholesterol Side-Chain Cleavage Enzyme; Chorionic Gonadotropin; Cyproterone; Cyproterone Acetate; Cytochrome P-450 Enzyme Inhibitors; Leydig Cells; Male; Metribolone; Rats; Rats, Inbred Strains; Steroid 17-alpha-Hydroxylase; Testosterone; Testosterone Congeners

1989
Interactions of an anti-androgen (cyproterone acetate) with the androgen receptor system and its biological action in the rat ventral prostate.
    Acta endocrinologica, 1985, Volume: 109, Issue:4

    Topics: Androgen Antagonists; Androstane-3,17-diol; Animals; Cyproterone; Cyproterone Acetate; Cytosol; Dihydrotestosterone; Estrenes; Male; Metribolone; Prostate; Rats; Rats, Inbred Strains; Receptors, Androgen; Receptors, Steroid; Testosterone

1985
Binding of glucocorticoid to the androgen receptor of mouse submandibular glands.
    The Journal of endocrinology, 1985, Volume: 106, Issue:3

    Topics: Animals; Binding, Competitive; Centrifugation, Density Gradient; Cyproterone; Cyproterone Acetate; Dexamethasone; Endopeptidases; Estradiol; Estrenes; Hydrocortisone; Male; Metribolone; Mice; Mice, Inbred Strains; Orchiectomy; Receptors, Androgen; Serine Endopeptidases; Submandibular Gland

1985
Androgen receptors in experimentally induced colon carcinogenesis.
    Journal of cancer research and clinical oncology, 1986, Volume: 112, Issue:1

    Topics: Animals; Azoxymethane; Binding Sites; Body Weight; Colon; Colonic Neoplasms; Cyproterone; Cyproterone Acetate; Cytosol; Estrenes; Kinetics; Male; Metribolone; Orchiectomy; Rats; Rats, Inbred Strains; Receptors, Androgen; Rectal Neoplasms; Testosterone

1986
Androgen-dependent growth regulation of and release of specific protein(s) by the androgen receptor containing human prostate tumor cell line LNCaP.
    The Prostate, 1986, Volume: 9, Issue:3

    Topics: Androgens; Cell Division; Cell Line; Cyproterone; Cyproterone Acetate; Dihydrotestosterone; Estrenes; Humans; Male; Metribolone; Neoplasm Proteins; Prostate; Prostatic Neoplasms; Receptors, Androgen; Triamcinolone Acetonide

1986
Characterization of androgen receptors in a transplantable human prostatic adenocarcinoma (PC-82).
    The Prostate, 1987, Volume: 10, Issue:2

    Topics: Adenocarcinoma; Cell Line; Cyproterone; Cyproterone Acetate; Dihydrotestosterone; Estradiol; Estrenes; Humans; Male; Metribolone; Molecular Weight; Neoplasm Transplantation; Progesterone; Prostatic Neoplasms; Receptors, Androgen; Testosterone; Triamcinolone Acetonide

1987
Stimulatory effects of androgen and antiandrogen on the in vitro proliferation of human mammary carcinoma cells.
    Journal of cancer research and clinical oncology, 1988, Volume: 114, Issue:6

    Topics: Androgen Antagonists; Androgens; Breast Neoplasms; Cell Division; Cyproterone; Cyproterone Acetate; Dihydrotestosterone; Estrenes; Estrogens; Female; Humans; Metribolone; Receptors, Androgen; Tumor Cells, Cultured

1988
Androgen interactions with intact nuclear envelopes from the rat ventral prostate.
    Journal of steroid biochemistry, 1985, Volume: 23, Issue:1

    Topics: Androgens; Animals; Binding, Competitive; Castration; Cell Fractionation; Cyproterone; Cyproterone Acetate; Dihydrotestosterone; Estrenes; Male; Metribolone; Nuclear Envelope; Prostate; Rats; Rats, Inbred Strains; Testosterone

1985
Regulation of 3 beta-hydroxysteroid dehydrogenase activity by human chorionic gonadotropin, androgens, and anti-androgens in cultured testicular cells.
    The Journal of biological chemistry, 1983, Sep-25, Volume: 258, Issue:18

    Topics: 3-Hydroxysteroid Dehydrogenases; Androgen Antagonists; Androgens; Animals; Cells, Cultured; Chorionic Gonadotropin; Cyproterone; Cyproterone Acetate; Estrenes; Humans; Male; Metribolone; Rats; Spironolactone; Testis; Testosterone

1983
Cyproterone acetate prevents translocation of the androgen receptor in the rat prostate.
    Molecular and cellular endocrinology, 1983, Volume: 32, Issue:2-3

    Topics: Androgen Antagonists; Animals; Binding, Competitive; Cyproterone; Cyproterone Acetate; Estrenes; In Vitro Techniques; Male; Metribolone; Prostate; Rats; Rats, Inbred Strains; Receptors, Androgen; Receptors, Steroid

1983
Inhibition of androgen binding in human foreskin fibroblasts by antiandrogens.
    Steroids, 1981, Volume: 37, Issue:6

    Topics: Androgen Antagonists; Androgens; Binding, Competitive; Cyproterone; Cyproterone Acetate; Dihydrotestosterone; Estrenes; Fibroblasts; Humans; Imidazoles; Imidazolidines; Infant, Newborn; Male; Metribolone; Penis; Receptors, Androgen; Receptors, Steroid; Subcellular Fractions; Testosterone

1981
Androgen steroid-receptor binding in the canine epididymis.
    The Prostate, 1981, Volume: 2, Issue:2

    Topics: Animals; Binding, Competitive; Castration; Centrifugation, Density Gradient; Cyproterone; Cyproterone Acetate; Dihydrotestosterone; Dogs; Epididymis; Estrenes; Male; Metribolone; Molecular Weight; Receptors, Androgen; Receptors, Steroid; Testosterone

1981
Androgen induction of follicular epithelial cell growth is mediated via insulin-like growth factor-I from dermal papilla cells.
    Biochemical and biophysical research communications, 1995, Jul-26, Volume: 212, Issue:3

    Topics: Antibodies; Base Sequence; Cell Division; Cells, Cultured; Cyproterone Acetate; DNA Primers; Epithelial Cells; Epithelium; Hair; Humans; Insulin-Like Growth Factor I; Metribolone; Molecular Sequence Data; Polymerase Chain Reaction; RNA, Messenger

1995
Interaction of antiandrogen-androgen receptor complexes with DNA and transcription activation.
    The Journal of steroid biochemistry and molecular biology, 1993, Volume: 46, Issue:6

    Topics: Androgen Antagonists; Animals; Binding, Competitive; Blotting, Western; Cell Line; Chloramphenicol O-Acetyltransferase; Chlorocebus aethiops; Cyproterone Acetate; Dihydrotestosterone; DNA; Flutamide; Gene Expression Regulation; Humans; Imidazoles; Imidazolidines; Kidney; Kinetics; Mammary Tumor Virus, Mouse; Metribolone; Receptors, Androgen; Recombinant Proteins; Transcription Factors; Transcription, Genetic; Transcriptional Activation; Transfection

1993
Effects of antiandrogens on transformation and transcription activation of wild-type and mutated (LNCaP) androgen receptors.
    The Journal of steroid biochemistry and molecular biology, 1993, Volume: 46, Issue:6

    Topics: Adenocarcinoma; Alanine; Amino Acid Sequence; Androgen Antagonists; Anilides; Animals; Blotting, Western; Cell Line; Cell Nucleus; Chloramphenicol O-Acetyltransferase; Cyproterone Acetate; Dose-Response Relationship, Drug; Flutamide; Humans; Male; Metribolone; Mutagenesis, Site-Directed; Nitriles; Point Mutation; Prostatic Neoplasms; Receptors, Androgen; Recombinant Proteins; Threonine; Tosyl Compounds; Transcription, Genetic; Transfection; Transformation, Genetic; Tumor Cells, Cultured

1993
Androgens augment vasoactive intestinal peptide- and growth hormone-releasing hormone-stimulated progestin production by rat granulosa cells.
    Endocrinology, 1993, Volume: 132, Issue:2

    Topics: 20-alpha-Dihydroprogesterone; Androgens; Animals; Cells, Cultured; Cyproterone Acetate; Diethylstilbestrol; Drug Synergism; Female; Granulosa Cells; Growth Hormone-Releasing Hormone; Hydrocortisone; Kinetics; Metribolone; Progesterone; Promegestone; Rats; Rats, Sprague-Dawley; Vasoactive Intestinal Peptide

1993
Androgen and glucocorticoid regulation of androgen receptor cDNA expression.
    Molecular and cellular endocrinology, 1995, Dec-29, Volume: 115, Issue:2

    Topics: Cell Line; Cyproterone Acetate; Cytomegalovirus; DNA, Complementary; Dose-Response Relationship, Drug; Down-Regulation; Flutamide; Gene Expression; Glucocorticoids; Humans; Metribolone; Promoter Regions, Genetic; Protein Biosynthesis; Receptors, Androgen; Receptors, Glucocorticoid; RNA, Messenger; Testosterone Congeners; Time Factors; Transfection; Tumor Cells, Cultured

1995
Activation of rat androgen receptor by androgenic ligands is unaffected by antiandrogens in Saccharomyces cerevisiae.
    Gene, 1998, Mar-16, Volume: 209, Issue:1-2

    Topics: Androgen Antagonists; Androgens; Animals; beta-Galactosidase; Cloning, Molecular; Cyproterone Acetate; Dihydrotestosterone; DNA Primers; Escherichia coli; Gene Expression Regulation; Metribolone; Mutagenesis, Site-Directed; Point Mutation; Rats; Receptors, Androgen; Recombinant Fusion Proteins; Saccharomyces cerevisiae; Testosterone

1998
Control of the proliferation of prostate cancer cells by an androgen and two antiandrogens. Cell specific sets of responses.
    The Journal of steroid biochemistry and molecular biology, 1998, Volume: 66, Issue:4

    Topics: Androgen Antagonists; Cell Division; Cyproterone Acetate; Genes, myc; Humans; Imidazoles; Kinetics; Male; Metribolone; Nitriles; Prostatic Neoplasms; Proto-Oncogene Proteins c-myc; RNA, Messenger; Testosterone Congeners; Transcription, Genetic; Tumor Cells, Cultured

1998
Specific recognition of androgens by their nuclear receptor. A structure-function study.
    The Journal of biological chemistry, 2000, Aug-04, Volume: 275, Issue:31

    Topics: Amino Acid Sequence; Androgen Antagonists; Androgen Receptor Antagonists; Androgens; Anilides; Binding Sites; Computer Simulation; Cyproterone Acetate; Dose-Response Relationship, Drug; Flutamide; Humans; Ligands; Metribolone; Models, Molecular; Molecular Sequence Data; Nitriles; Progesterone; Promegestone; Receptors, Androgen; Sequence Alignment; Tosyl Compounds; Transcriptional Activation

2000
Rapid androgen actions on calcium signaling in rat sertoli cells and two human prostatic cell lines: similar biphasic responses between 1 picomolar and 100 nanomolar concentrations.
    Biology of reproduction, 2000, Volume: 63, Issue:3

    Topics: Androgen Antagonists; Androgens; Animals; Calcium Signaling; Cell Line; Cyproterone Acetate; Dihydrotestosterone; Dose-Response Relationship, Drug; Flutamide; Gap Junctions; Humans; Kinetics; Male; Metribolone; Prostate; Prostatic Neoplasms; Rats; Rats, Wistar; Sertoli Cells; Testosterone; Tumor Cells, Cultured

2000
Evidence that chlormadinone acetate exhibits antiandrogenic activity in androgen-dependent cell line.
    Molecular and cellular endocrinology, 2002, Dec-30, Volume: 198, Issue:1-2

    Topics: Active Transport, Cell Nucleus; Androgen Antagonists; Androgens; Animals; Cell Line; Chlormadinone Acetate; Cyproterone Acetate; Female; Genes, Reporter; Humans; Male; Metribolone; Molecular Structure; Receptors, Androgen; Recombinant Fusion Proteins; Transcriptional Activation

2002
Mutation of the androgen receptor at amino acid 708 (Gly-->Ala) abolishes partial agonist activity of steroidal antiandrogens.
    Molecular pharmacology, 2003, Volume: 63, Issue:4

    Topics: Alanine; Amino Acid Substitution; Androgen Antagonists; Animals; Binding Sites; Chlorocebus aethiops; COS Cells; Cyproterone Acetate; Glycine; Humans; Metribolone; Models, Molecular; Mutation; Protein Conformation; Receptors, Androgen; Testosterone Congeners; Transcriptional Activation; Transfection; Tritium

2003
Differential modulation of androgen receptor transcriptional activity by the nuclear receptor co-repressor (N-CoR).
    The Biochemical journal, 2004, May-01, Volume: 379, Issue:Pt 3

    Topics: Androgen Antagonists; Androgen Receptor Antagonists; Animals; Binding, Competitive; Cell Line, Tumor; CHO Cells; Cricetinae; Cyproterone Acetate; Down-Regulation; Gene Expression Regulation; Ligands; Male; Metribolone; Mice; Mifepristone; Mutation; Nuclear Proteins; Nuclear Receptor Co-Repressor 1; Nuclear Receptor Coactivator 2; Promoter Regions, Genetic; Prostatic Neoplasms; Receptors, Androgen; Repressor Proteins; Transcription Factors; Transcription, Genetic; Transfection

2004
Ligand-specific dynamics of the androgen receptor at its response element in living cells.
    Molecular and cellular biology, 2007, Volume: 27, Issue:5

    Topics: Adenocarcinoma; Androgen Antagonists; Androgens; Anilides; Animals; Cell Line, Tumor; Chromatin Assembly and Disassembly; Cyproterone Acetate; Dihydrotestosterone; Female; Fluorescence Recovery After Photobleaching; Flutamide; Genes, Reporter; Green Fluorescent Proteins; In Situ Hybridization, Fluorescence; Ligands; Luciferases; Mammary Neoplasms, Animal; Mammary Tumor Virus, Mouse; Metribolone; Mice; Microscopy, Video; Mifepristone; Models, Biological; Nitriles; Plasmids; Promoter Regions, Genetic; Receptors, Androgen; Response Elements; Testosterone; Tosyl Compounds; Transcription, Genetic

2007
Androgen receptor amplification is reflected in the transcriptional responses of Vertebral-Cancer of the Prostate cells.
    Molecular and cellular endocrinology, 2011, Jan-01, Volume: 331, Issue:1

    Topics: Androgens; Anilides; Cell Line, Tumor; Chromatin; Cyproterone Acetate; Dose-Response Relationship, Drug; Down-Regulation; Gene Expression Regulation, Neoplastic; Gene Silencing; Humans; Male; Metribolone; Nitriles; Phenylthiohydantoin; Prostatic Neoplasms; Receptors, Androgen; Tosyl Compounds; Transcription, Genetic

2011