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cyproterone acetate and hydroxyflutamide

cyproterone acetate has been researched along with hydroxyflutamide in 28 studies

Research

Studies (28)

Timeframe	Studies, this research(%)	All Research%
pre-1990	4 (14.29)	18.7374
1990's	12 (42.86)	18.2507
2000's	10 (35.71)	29.6817
2010's	2 (7.14)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Ackerman, JH; Bell, MR; Christiansen, RG; D'Ambra, TE; Herrmann, JL; Kullnig, RK; Mallamo, JP; Opalka, CJ; Snyder, BW; Winneker, RC	1
Edwards, JP; Farmer, LJ; Hamann, LG; Higuchi, RI; Jones, TK; Kong, JW; Marschke, KB; Wang, XN; Zhi, L	1
Arbusow, V; Bojar, H; Fittler, F; Klobeck, HG; Schulz, P; Wolf, D	1
Baylink, DJ; Farley, JR; Kasperk, CH; Linkhart, TA; Turner, RT; Wergedal, JE	1
Gangnerau, MN; Picon, R	1
Dias, JA; Swift, TA	1
Ayub, M; Levell, MJ	1
Biordi, L; Bologna, M; Festuccia, C; Muzi, P; Vicentini, C	1
Govindan, MV; Koutsilieris, M; Pagé, N; Warriar, N	2
Berrevoets, CA; Mulder, E; Veldscholte, J	1
Sar, M; Wilson, EM; Wong, CI; Zhou, ZX	1
Burnstein, KL; Cameron, DJ; Dai, JL; Maiorino, CA	1
Gurpide, E; Markiewicz, L	1
Chang, C; Miyamoto, H; Wilding, G; Yeh, S	1
Cavazzini, P; degli Uberti, EC; del Senno, L; Fallo, F; Rossi, R; Valentini, A; Zatelli, MC	1
Lumbroso, S; Moras, D; Nicolas, JC; Poujol, N; Sultan, C; Tahiri, B; Wurtz, JM	1
Jones, GR; Lyng, FM; Rommerts, FF	1
Danielsen, M; Harris, VK; List, HJ; Martinez, E; Riegel, AT; Smith, CL	1
Baniahmad, A; Cato, AC; Dotzlaw, H; Iñiguez Lluhí, JA; Mink, S; Moehren, U	1
Jänne, OA; Karvonen, U; Palvimo, JJ	1
Bonmassar, E; Faraoni, I; Missale, C; Rizzetti, MC; Sigala, S; Spano, P; Tognazzi, N	1
Asim, M; Baniahmad, A; Dotzlaw, H; Papaioannou, M; Reeb, C	1
Chang, CY; Elbi, C; Hager, GL; Hendarwanto, A; Klokk, TI; Kurys, P; Nagaich, AK; Saatcioglu, F; Slagsvold, T	1
De Rosier, T; Eliason, HC; Ervin, KM; Gowda, K; Kupcho, KR; Marks, BD; Ozers, MS; Qadir, N; Riddle, SM; Shekhani, MS	1
Hara, S; Hyochi, N; Isaacs, JT; Ishioka, J; Kageyama, Y; Kihara, K; Singh, P; Urushibara, M	1
Dubbink, HJ; Hersmus, R; Jenster, G; Lusher, SJ; Molier, M; Trapman, J; van de Wijngaart, DJ	1
Begum, S; Bevan, CL; Brooke, GN; Bryan, RA; Dart, DA; Fioretti, FM; Gamble, SC; Hough, MA; Odontiadis, M; Powell, SM; Wait, R; Waxman, J	1

Other Studies

28 other study(ies) available for cyproterone acetate and hydroxyflutamide

Article	Year
Antiandrogenic steroidal sulfonylpyrazoles. Journal of medicinal chemistry, 1990, Volume: 33, Issue:8 Topics: Androgen Antagonists; Animals; Male; Molecular Structure; Orchiectomy; Organ Size; Pregnanes; Prostate; Pyrazoles; Rats; Rats, Inbred Strains; Receptors, Androgen; Structure-Activity Relationship; Testosterone; X-Ray Diffraction	1990
Synthesis and biological activity of a novel series of nonsteroidal, peripherally selective androgen receptor antagonists derived from 1,2-dihydropyridono[5,6-g]quinolines. Journal of medicinal chemistry, 1998, Feb-12, Volume: 41, Issue:4 Topics: Androgen Antagonists; Androgen Receptor Antagonists; Animals; Cell Line; COS Cells; Dihydropyridines; Dihydrotestosterone; Gonadotropins; Heterocyclic Compounds; Humans; Indicators and Reagents; Male; Molecular Structure; Orchiectomy; Prostate; Quinolines; Rats; Rats, Sprague-Dawley; Receptors, Androgen; Receptors, Progesterone; Recombinant Proteins; Seminal Vesicles; Structure-Activity Relationship; Testosterone; Transfection	1998
The synthetic androgen mibolerone induces transient suppression of the transformed phenotype in an androgen responsive human prostatic carcinoma cell line. Andrologia, 1990, Volume: 22 Suppl 1 Topics: Androgen Antagonists; Androgens; Cell Division; Cell Transformation, Neoplastic; Cyproterone; Cyproterone Acetate; Dihydrotestosterone; Flutamide; Humans; Male; Nandrolone; Prostatic Neoplasms; Receptors, Androgen; RNA, Messenger; Tumor Cells, Cultured	1990
Androgens directly stimulate proliferation of bone cells in vitro. Endocrinology, 1989, Volume: 124, Issue:3 Topics: Alkaline Phosphatase; Androgens; Animals; Binding, Competitive; Cell Count; Cell Differentiation; Cell Division; Cyproterone; Cyproterone Acetate; Dihydrotestosterone; DNA; Dose-Response Relationship, Drug; Fluoxymesterone; Flutamide; Humans; Methenolone; Mice; Osteoblasts; Testosterone; Tumor Cells, Cultured	1989
Onset of steroidogenesis and differentiation of functional LH receptors in rat fetal testicular cultures. Archives of andrology, 1987, Volume: 18, Issue:3 Topics: Aminoglutethimide; Animals; Binding, Competitive; Bucladesine; Cyproterone; Cyproterone Acetate; Dehydroepiandrosterone; Flutamide; Gestational Age; Luteinizing Hormone; Male; Organ Culture Techniques; Progesterone; Rats; Rats, Inbred Strains; Receptors, LH; Testis; Testosterone	1987
Testosterone suppression of ornithine decarboxylase activity in rat Sertoli cells. Endocrinology, 1988, Volume: 123, Issue:2 Topics: Animals; Bucladesine; Cells, Cultured; Cyclic AMP; Cyproterone; Cyproterone Acetate; Dihydrotestosterone; Enzyme Induction; Estradiol; Flutamide; Follicle Stimulating Hormone; Male; Ornithine Decarboxylase; Rats; Rats, Inbred Strains; Sertoli Cells; Testosterone	1988
Inhibition of rat testicular 17 alpha-hydroxylase and 17,20-lyase activities by anti-androgens (flutamide, hydroxyflutamide, RU23908, cyproterone acetate) in vitro. Journal of steroid biochemistry, 1987, Volume: 28, Issue:1 Topics: Aldehyde-Lyases; Androgen Antagonists; Animals; Cyproterone; Cyproterone Acetate; Cytochrome P-450 Enzyme System; Flutamide; Imidazoles; Imidazolidines; Kinetics; Male; Microsomes; Rats; Rats, Inbred Strains; Steroid 17-alpha-Hydroxylase; Steroid Hydroxylases; Testis	1987
Finasteride dose-dependently reduces the proliferation rate of the LnCap human prostatic cancer cell line in vitro. Urology, 1995, Volume: 45, Issue:2 Topics: Androgen Antagonists; Cell Division; Cyproterone Acetate; Dihydrotestosterone; Dose-Response Relationship, Drug; Finasteride; Flutamide; Humans; Linear Models; Male; Prostatic Neoplasms; Testosterone; Tumor Cells, Cultured	1995
Antiandrogens inhibit human androgen receptor-dependent gene transcription activation in the human prostate cancer cells LNCaP. The Prostate, 1994, Volume: 24, Issue:4 Topics: Amino Acid Sequence; Androgen Antagonists; Binding, Competitive; Blotting, Western; Chloramphenicol O-Acetyltransferase; Cyproterone Acetate; Dihydrotestosterone; Dose-Response Relationship, Drug; Flutamide; Gene Expression Regulation, Viral; Humans; Imidazoles; Imidazolidines; Male; Mammary Tumor Virus, Mouse; Molecular Sequence Data; Promoter Regions, Genetic; Prostatic Neoplasms; Receptors, Androgen; Transcription, Genetic; Transfection; Tumor Cells, Cultured	1994
Interaction of antiandrogen-androgen receptor complexes with DNA and transcription activation. The Journal of steroid biochemistry and molecular biology, 1993, Volume: 46, Issue:6 Topics: Androgen Antagonists; Animals; Binding, Competitive; Blotting, Western; Cell Line; Chloramphenicol O-Acetyltransferase; Chlorocebus aethiops; Cyproterone Acetate; Dihydrotestosterone; DNA; Flutamide; Gene Expression Regulation; Humans; Imidazoles; Imidazolidines; Kidney; Kinetics; Mammary Tumor Virus, Mouse; Metribolone; Receptors, Androgen; Recombinant Proteins; Transcription Factors; Transcription, Genetic; Transcriptional Activation; Transfection	1993
Effects of antiandrogens on transformation and transcription activation of wild-type and mutated (LNCaP) androgen receptors. The Journal of steroid biochemistry and molecular biology, 1993, Volume: 46, Issue:6 Topics: Adenocarcinoma; Alanine; Amino Acid Sequence; Androgen Antagonists; Anilides; Animals; Blotting, Western; Cell Line; Cell Nucleus; Chloramphenicol O-Acetyltransferase; Cyproterone Acetate; Dose-Response Relationship, Drug; Flutamide; Humans; Male; Metribolone; Mutagenesis, Site-Directed; Nitriles; Point Mutation; Prostatic Neoplasms; Receptors, Androgen; Recombinant Proteins; Threonine; Tosyl Compounds; Transcription, Genetic; Transfection; Transformation, Genetic; Tumor Cells, Cultured	1993
Steroid requirement for androgen receptor dimerization and DNA binding. Modulation by intramolecular interactions between the NH2-terminal and steroid-binding domains. The Journal of biological chemistry, 1993, Sep-05, Volume: 268, Issue:25 Topics: Androgens; Animals; Baculoviridae; Base Sequence; Binding Sites; Cell Line; Cyproterone Acetate; DNA; Flutamide; Genetic Vectors; Humans; Macromolecular Substances; Mifepristone; Molecular Sequence Data; Moths; Receptors, Androgen; Recombinant Proteins; Transfection	1993
Androgen and glucocorticoid regulation of androgen receptor cDNA expression. Molecular and cellular endocrinology, 1995, Dec-29, Volume: 115, Issue:2 Topics: Cell Line; Cyproterone Acetate; Cytomegalovirus; DNA, Complementary; Dose-Response Relationship, Drug; Down-Regulation; Flutamide; Gene Expression; Glucocorticoids; Humans; Metribolone; Promoter Regions, Genetic; Protein Biosynthesis; Receptors, Androgen; Receptors, Glucocorticoid; RNA, Messenger; Testosterone Congeners; Time Factors; Transfection; Tumor Cells, Cultured	1995
Estrogenic and progestagenic activities of physiologic and synthetic androgens, as measured by in vitro bioassays. Methods and findings in experimental and clinical pharmacology, 1997, Volume: 19, Issue:4 Topics: Adenocarcinoma; Alkaline Phosphatase; Androgen Antagonists; Androgens; Breast Neoplasms; Cyproterone Acetate; Endometrial Neoplasms; Estradiol; Estrogen Antagonists; Female; Flutamide; Gonanes; Humans; Mifepristone; Polyunsaturated Alkamides; Progestins; Tamoxifen; Testosterone; Testosterone Congeners; Tumor Cells, Cultured	1997
Promotion of agonist activity of antiandrogens by the androgen receptor coactivator, ARA70, in human prostate cancer DU145 cells. Proceedings of the National Academy of Sciences of the United States of America, 1998, Jun-23, Volume: 95, Issue:13 Topics: Androgen Antagonists; Androgens; Anilides; Cyproterone Acetate; Drug Interactions; Flutamide; Humans; Imidazoles; Male; Mifepristone; Nitriles; Nuclear Receptor Coactivators; Oncogene Proteins; Prostatic Neoplasms; Protein Binding; Protein Conformation; Tosyl Compounds; Trans-Activators; Transcription Factors; Transcriptional Activation; Tumor Cells, Cultured	1998
Evidence for androgen receptor gene expression and growth inhibitory effect of dihydrotestosterone on human adrenocortical cells. The Journal of endocrinology, 1998, Volume: 159, Issue:3 Topics: Adrenal Cortex; Androgen Antagonists; Cell Division; Cells, Cultured; Cyproterone Acetate; Dihydrotestosterone; Female; Flutamide; Gene Expression; Humans; Immunohistochemistry; Male; Receptors, Androgen; Reverse Transcriptase Polymerase Chain Reaction; Tumor Cells, Cultured	1998
Specific recognition of androgens by their nuclear receptor. A structure-function study. The Journal of biological chemistry, 2000, Aug-04, Volume: 275, Issue:31 Topics: Amino Acid Sequence; Androgen Antagonists; Androgen Receptor Antagonists; Androgens; Anilides; Binding Sites; Computer Simulation; Cyproterone Acetate; Dose-Response Relationship, Drug; Flutamide; Humans; Ligands; Metribolone; Models, Molecular; Molecular Sequence Data; Nitriles; Progesterone; Promegestone; Receptors, Androgen; Sequence Alignment; Tosyl Compounds; Transcriptional Activation	2000
Rapid androgen actions on calcium signaling in rat sertoli cells and two human prostatic cell lines: similar biphasic responses between 1 picomolar and 100 nanomolar concentrations. Biology of reproduction, 2000, Volume: 63, Issue:3 Topics: Androgen Antagonists; Androgens; Animals; Calcium Signaling; Cell Line; Cyproterone Acetate; Dihydrotestosterone; Dose-Response Relationship, Drug; Flutamide; Gap Junctions; Humans; Kinetics; Male; Metribolone; Prostate; Prostatic Neoplasms; Rats; Rats, Wistar; Sertoli Cells; Testosterone; Tumor Cells, Cultured	2000
Effects of antiandrogens on chromatin remodeling and transcription of the integrated mouse mammary tumor virus promoter. Experimental cell research, 2000, Oct-10, Volume: 260, Issue:1 Topics: Androgen Antagonists; Animals; Base Sequence; Chromatin; Cyproterone Acetate; DNA Probes; Female; Flutamide; L Cells; Male; Mammary Tumor Virus, Mouse; Mice; Promoter Regions, Genetic; Receptors, Androgen; Transcriptional Activation	2000
The amino terminus of the human AR is target for corepressor action and antihormone agonism. Molecular endocrinology (Baltimore, Md.), 2002, Volume: 16, Issue:4 Topics: Androgen Antagonists; Anilides; Animals; Catalytic Domain; Cell Line; Cyclic AMP-Dependent Protein Kinases; Cyproterone Acetate; DNA-Binding Proteins; Flutamide; Haplorhini; Humans; Ligands; Male; Nitriles; Nuclear Receptor Co-Repressor 2; Point Mutation; Protein Conformation; Receptors, Androgen; Repressor Proteins; Tosyl Compounds; Transcriptional Activation; Transfection	2002
Pure antiandrogens disrupt the recruitment of coactivator GRIP1 to colocalize with androgen receptor in nuclei. FEBS letters, 2002, Jul-17, Volume: 523, Issue:1-3 Topics: Active Transport, Cell Nucleus; Androgen Antagonists; Androgens; Anilides; Animals; Cell Nucleus; Chlorocebus aethiops; COS Cells; Cyproterone Acetate; Flutamide; Nitriles; Nuclear Receptor Coactivator 2; Receptors, Androgen; Subcellular Fractions; Tosyl Compounds; Transcription Factors; Transcriptional Activation	2002
Nerve growth factor induces the re-expression of functional androgen receptors and p75(NGFR) in the androgen-insensitive prostate cancer cell line DU145. European journal of endocrinology, 2002, Volume: 147, Issue:3 Topics: Androgen Antagonists; Androgens; Apoptosis; Cell Division; Cyproterone Acetate; Dihydrotestosterone; Flutamide; Gene Expression; Humans; Male; Nerve Growth Factor; Prostatic Neoplasms; Receptor, Nerve Growth Factor; Receptors, Androgen; RNA, Messenger; Telomerase; Tumor Cells, Cultured	2002
Co-activator and co-repressor interplay on the human androgen receptor. Andrologia, 2005, Volume: 37, Issue:6 Topics: Androgen Antagonists; Androgen-Binding Protein; Androgens; Anilides; Cyproterone Acetate; Flutamide; Humans; Ligands; Male; Nitriles; Protein Binding; Receptors, Androgen; Repressor Proteins; Response Elements; Time Factors; Tosyl Compounds; Trans-Activators; Transcriptional Activation	2005
Ligand-specific dynamics of the androgen receptor at its response element in living cells. Molecular and cellular biology, 2007, Volume: 27, Issue:5 Topics: Adenocarcinoma; Androgen Antagonists; Androgens; Anilides; Animals; Cell Line, Tumor; Chromatin Assembly and Disassembly; Cyproterone Acetate; Dihydrotestosterone; Female; Fluorescence Recovery After Photobleaching; Flutamide; Genes, Reporter; Green Fluorescent Proteins; In Situ Hybridization, Fluorescence; Ligands; Luciferases; Mammary Neoplasms, Animal; Mammary Tumor Virus, Mouse; Metribolone; Mice; Microscopy, Video; Mifepristone; Models, Biological; Nitriles; Plasmids; Promoter Regions, Genetic; Receptors, Androgen; Response Elements; Testosterone; Tosyl Compounds; Transcription, Genetic	2007
The androgen receptor T877A mutant recruits LXXLL and FXXLF peptides differently than wild-type androgen receptor in a time-resolved fluorescence resonance energy transfer assay. Biochemistry, 2007, Jan-23, Volume: 46, Issue:3 Topics: Amino Acid Sequence; Amino Acid Substitution; Androgen Antagonists; Anilides; Animals; Cyproterone Acetate; Dihydrotestosterone; Fluoresceins; Fluorescence Resonance Energy Transfer; Flutamide; Ligands; Mifepristone; Nitriles; Oligopeptides; Rats; Receptors, Androgen; Tosyl Compounds	2007
Effects of steroidal and non-steroidal antiandrogens on wild-type and mutant androgen receptors. The Prostate, 2007, Jun-01, Volume: 67, Issue:8 Topics: Allylestrenol; Androgen Antagonists; Androgen Receptor Antagonists; Androgens; Anilides; Cyproterone Acetate; Flutamide; Humans; Imidazolidines; Male; Models, Molecular; Mutagenesis, Site-Directed; Neoplasms, Hormone-Dependent; Nitriles; Plasmids; Prostate-Specific Antigen; Prostatic Neoplasms; Receptors, Androgen; Reverse Transcriptase Polymerase Chain Reaction; RNA, Neoplasm; Testosterone; Tosyl Compounds; Transcription, Genetic; Transfection	2007
Systematic structure-function analysis of androgen receptor Leu701 mutants explains the properties of the prostate cancer mutant L701H. The Journal of biological chemistry, 2010, Feb-12, Volume: 285, Issue:7 Topics: Androgen Antagonists; Anilides; Blotting, Western; Cell Line, Tumor; Cyproterone Acetate; Dihydrotestosterone; Flutamide; Humans; Hydrocortisone; Hydrophobic and Hydrophilic Interactions; Male; Mutation; Nitriles; Progesterone; Prostatic Neoplasms; Protein Structure, Secondary; Receptors, Androgen; Steroids; Structure-Activity Relationship; Tosyl Compounds	2010
Antiandrogens act as selective androgen receptor modulators at the proteome level in prostate cancer cells. Molecular & cellular proteomics : MCP, 2015, Volume: 14, Issue:5 Topics: Amino Acid Sequence; Androgen Antagonists; Anilides; Cell Line, Tumor; Cyproterone Acetate; Flutamide; Gene Expression Regulation, Neoplastic; Humans; Male; Molecular Sequence Annotation; Molecular Sequence Data; Mutation; Nandrolone; Neoplasm Proteins; Nitriles; Prostate; Proteome; Receptors, Androgen; Signal Transduction; Tosyl Compounds	2015