cyproheptadine and triprolidine

cyproheptadine has been researched along with triprolidine in 12 studies

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19904 (33.33)18.7374
1990's5 (41.67)18.2507
2000's1 (8.33)29.6817
2010's2 (16.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Andrews, PR; Craik, DJ; Martin, JL1
Donné-Op den Kelder, GM; ter Laak, AM; Timmerman, H; Venhorst, J1
Bollen, A; Garcia, L; Gillard, M; Guillaume, JP; Moguilevsky, N; Noyer, M; Szpirer, C; Szpirer, J; Varsalona, F1
Bleich, S; Gulbins, E; Kornhuber, J; Reichel, M; Terfloth, L; Tripal, P; Wiltfang, J1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Dan, S; Fujiwara, T; Handa, N; Hirano, T; Ito, A; Kagechika, H; Nishino, N; Niwa, H; Ogawa, K; Okamura, M; Sonoda, T; Takemoto, Y; Tariq, M; Umehara, T; Yamori, T; Yokoyama, S; Yoshida, M1
Feldman, JM; Plank, J1
Donné-op den Kelder, GM; Timmerman, H; van Drooge, MJ1
Fräki, JE; Gibson, JR; Neittaanmäki, H1
Anderson, W; Maling, HM; Webster, ME; Williams, MA; Zweig, MH1
Harada, M; Kimura, S; Nagata, M; Takeuchi, M; Watanabe, A1

Reviews

2 review(s) available for cyproheptadine and triprolidine

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Three new non-sedative antihistamines: worth keeping an eye open for.
    Drug and therapeutics bulletin, 1990, May-14, Volume: 28, Issue:10

    Topics: Cetirizine; Cyproheptadine; Histamine H1 Antagonists; Humans; Hydroxyzine; Loratadine; Rhinitis, Allergic, Seasonal; Triprolidine; Urticaria

1990

Trials

1 trial(s) available for cyproheptadine and triprolidine

ArticleYear
Comparison of the new antihistamine acrivastine (BW 825C) versus cyproheptadine in the treatment of idiopathic cold urticaria.
    Dermatologica, 1988, Volume: 177, Issue:2

    Topics: Adult; Clinical Trials as Topic; Cold Temperature; Cyproheptadine; Double-Blind Method; Female; Histamine H1 Antagonists; Humans; Male; Placebos; Pyridines; Random Allocation; Sleep Stages; Triprolidine; Urticaria

1988

Other Studies

9 other study(ies) available for cyproheptadine and triprolidine

ArticleYear
Functional group contributions to drug-receptor interactions.
    Journal of medicinal chemistry, 1984, Volume: 27, Issue:12

    Topics: Animals; Calorimetry; Kinetics; Models, Biological; Protein Binding; Receptors, Cell Surface; Receptors, Drug; Structure-Activity Relationship

1984
The histamine H1-receptor antagonist binding site. A stereoselective pharmacophoric model based upon (semi-)rigid H1-antagonists and including a known interaction site on the receptor.
    Journal of medicinal chemistry, 1995, Aug-18, Volume: 38, Issue:17

    Topics: Binding Sites; Histamine H1 Antagonists; Models, Molecular; Molecular Conformation; Stereoisomerism

1995
Stable expression of human H1-histamine-receptor cDNA in Chinese hamster ovary cells. Pharmacological characterisation of the protein, tissue distribution of messenger RNA and chromosomal localisation of the gene.
    European journal of biochemistry, 1994, Sep-01, Volume: 224, Issue:2

    Topics: Amino Acid Sequence; Animals; Base Sequence; Cattle; CHO Cells; Chromosome Mapping; Chromosomes, Human, Pair 3; Cloning, Molecular; Cricetinae; DNA Primers; DNA, Complementary; Gene Expression; Gene Library; GTP-Binding Proteins; Guinea Pigs; Humans; Kinetics; Lung; Molecular Sequence Data; Polymerase Chain Reaction; Pyrilamine; Rats; Receptors, Histamine H1; Recombinant Proteins; Sequence Homology, Amino Acid; Transfection

1994
Identification of new functional inhibitors of acid sphingomyelinase using a structure-property-activity relation model.
    Journal of medicinal chemistry, 2008, Jan-24, Volume: 51, Issue:2

    Topics: Algorithms; Animals; Cell Line; Cell Line, Tumor; Chemical Phenomena; Chemistry, Physical; Enzyme Inhibitors; Humans; Hydrogen-Ion Concentration; Molecular Conformation; Quantitative Structure-Activity Relationship; Rats; Sphingomyelin Phosphodiesterase

2008
Identification of Cyproheptadine as an Inhibitor of SET Domain Containing Lysine Methyltransferase 7/9 (Set7/9) That Regulates Estrogen-Dependent Transcription.
    Journal of medicinal chemistry, 2016, 04-28, Volume: 59, Issue:8

    Topics: Crystallography, X-Ray; Cyproheptadine; Enzyme Inhibitors; Estrogen Receptor alpha; Estrogens; Histone-Lysine N-Methyltransferase; Humans; MCF-7 Cells; Molecular Structure; Transcription, Genetic

2016
Adrenal function in the carcinoid syndrome: effects of the serotonin antagonist cyproheptadine.
    Metabolism: clinical and experimental, 1975, Volume: 24, Issue:9

    Topics: 17-Hydroxycorticosteroids; Adrenal Glands; Aged; Carcinoid Tumor; Circadian Rhythm; Cyproheptadine; Female; Humans; Hydrocortisone; Hydroxyindoleacetic Acid; Insulin; Male; Metyrapone; Middle Aged; Serotonin; Triprolidine

1975
The histamine H1-receptor antagonist binding site. Part I: Active conformation of cyproheptadine.
    Journal of computer-aided molecular design, 1991, Volume: 5, Issue:4

    Topics: Binding Sites; Cyproheptadine; Histamine H1 Antagonists; Models, Molecular; Molecular Conformation; Molecular Structure; Pyridines; Software; Thermodynamics; Triprolidine

1991
Urate crystal induced inflammation in the rat: evidence for the combined actions of kinins, histamine and components of complement.
    Immunological communications, 1972, Volume: 1, Issue:2

    Topics: Animals; Carboxypeptidases; Colchicine; Complement System Proteins; Cyproheptadine; Edema; Female; Gout; Histamine; Kinins; Male; Methysergide; Promethazine; Rats; Serotonin; Tripelennamine; Triprolidine; Trypsin Inhibitors; Uric Acid

1972
Suppressive effects of antihistaminic and/or anti-PAF agents on passive anaphylactic shock in mice sensitized with allogeneic monoclonal IgE and IgG1 antibodies and hyperimmune serum.
    Immunological investigations, 1998, Volume: 27, Issue:6

    Topics: Anaphylaxis; Animals; Antibodies, Monoclonal; Cattle; Cyproheptadine; Female; Histamine H1 Antagonists; Immunoglobulin E; Immunoglobulin G; Immunosuppressive Agents; Isoantibodies; Male; Mice; Mice, Inbred BALB C; Mice, Inbred C3H; Mice, Inbred C57BL; Mice, Nude; Piperazines; Platelet Activating Factor; Propranolol; Pyridinium Compounds; Serum Albumin, Bovine; Triprolidine

1998