cyproheptadine and promethazine

cyproheptadine has been researched along with promethazine in 35 studies

Research

Studies (35)

TimeframeStudies, this research(%)All Research%
pre-199027 (77.14)18.7374
1990's2 (5.71)18.2507
2000's4 (11.43)29.6817
2010's2 (5.71)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Creveling, CR; Daly, JW; Lewandowski, GA; McNeal, ET1
Chiang, GH; Unger, SH1
Strassburg, CP; Tukey, RH1
Bleich, S; Gulbins, E; Kornhuber, J; Reichel, M; Terfloth, L; Tripal, P; Wiltfang, J1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Hirata, M1
Hill, DF; Hungen, KV; Roberts, S1
Klimek, V; Maj, J; Rawlów, A; Sarnek, J1
Eltze, M; Lambrecht, G; Mutschler, E1
Coughtrie, MW; Mak, LY; Sharp, S; Smith, DJ1
Winter, JC1
Orthen-Gambill, N1
Bailenger, J; Lacassie, A1
Gaut, ZN2
Rohan, P1
Achari, G; Sinha, SP1
Barnett, A; Roth, FE; Taber, RI1
Alphin, RS; Ward, JW1
Barnett, A; Malick, JB; Taber, RI1
Gerald, MC; Maickel, RP; Skau, KA1
Dobozy, A; Hunyadi, J; Simon, N1
Aghajanian, GK; Bennett, JL1
Anderson, W; Maling, HM; Webster, ME; Williams, MA; Zweig, MH1
DiPasquale, G; Martin, J; Rassaert, CL; Richter, RS1
Selye, H1
Furukawa, CT1
Imanishi, H; Kamei, H; Murata, S; Nishiyama, Y; Tomatsu, K1
Hendry, JS; Minnema, DJ; Rosecrans, JA1
HEMINGWAY, GC; ZEPPA, R1
HERXHEIMER, H; STRESEMANN, E1
DIEUDONNE, JM1
Bertollo, CM; Coelho, MM; Costa, KA; Glória, MB; Moraes-Santos, T; Nascimento, EB; Oliveira, AC; Rocha, LT; Souza, AL1
Buckle, H; Keane, G; O'Brien, N; Pache, D; Scott, J1

Reviews

2 review(s) available for cyproheptadine and promethazine

ArticleYear
Human UDP-glucuronosyltransferases: metabolism, expression, and disease.
    Annual review of pharmacology and toxicology, 2000, Volume: 40

    Topics: Autoimmunity; Chromosome Mapping; Glucuronides; Glucuronosyltransferase; Humans; Hyperbilirubinemia; Neoplasms; Steroids; Terminology as Topic

2000
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Other Studies

33 other study(ies) available for cyproheptadine and promethazine

ArticleYear
[3H]Batrachotoxinin A 20 alpha-benzoate binding to voltage-sensitive sodium channels: a rapid and quantitative assay for local anesthetic activity in a variety of drugs.
    Journal of medicinal chemistry, 1985, Volume: 28, Issue:3

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Anesthetics, Local; Animals; Batrachotoxins; Calcium Channel Blockers; Cyclic AMP; Guinea Pigs; Histamine H1 Antagonists; In Vitro Techniques; Ion Channels; Neurotoxins; Sodium; Tranquilizing Agents; Tritium

1985
Octanol-physiological buffer distribution coefficients of lipophilic amines by reversed-phase high-performance liquid chromatography and their correlation with biological activity.
    Journal of medicinal chemistry, 1981, Volume: 24, Issue:3

    Topics: Amines; Animals; Buffers; Chromatography, High Pressure Liquid; Histamine Release; Lipid Metabolism; Octanols; Protein Binding; Rats; Serum Albumin, Bovine; Sodium-Potassium-Exchanging ATPase; Solubility; Structure-Activity Relationship

1981
Identification of new functional inhibitors of acid sphingomyelinase using a structure-property-activity relation model.
    Journal of medicinal chemistry, 2008, Jan-24, Volume: 51, Issue:2

    Topics: Algorithms; Animals; Cell Line; Cell Line, Tumor; Chemical Phenomena; Chemistry, Physical; Enzyme Inhibitors; Humans; Hydrogen-Ion Concentration; Molecular Conformation; Quantitative Structure-Activity Relationship; Rats; Sphingomyelin Phosphodiesterase

2008
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Inhibitory effects of antihistamines and antiserotonins on the bone marrow reactions produced by Escherichia coli endotoxin in mice.
    The Journal of infectious diseases, 1975, Volume: 132, Issue:6

    Topics: Animals; Bone Marrow Diseases; Chlorpromazine; Cyproheptadine; Diphenhydramine; Endotoxins; Escherichia coli; Histamine; Histamine H1 Antagonists; Male; Mice; Phenobarbital; Promethazine; Serotonin Antagonists

1975
Interactions between lysergic acid diethylamide and dopamine-sensitive adenylate cyclase systems in rat brain.
    Brain research, 1975, Aug-22, Volume: 94, Issue:1

    Topics: Adenylyl Cyclases; Animals; Brain; Chlorpromazine; Corpus Striatum; Cyproheptadine; Dopamine; Dose-Response Relationship, Drug; Enzyme Activation; Hallucinogens; Haloperidol; Hippocampus; Lysergic Acid Diethylamide; Male; Methysergide; Norepinephrine; Promethazine; Propranolol; Serotonin; Thioridazine; Trifluoperazine

1975
On the anticataleptic action of cyproheptadine.
    Pharmacology, biochemistry, and behavior, 1976, Volume: 5, Issue:2

    Topics: Animals; Atropine; Catalepsy; Clomipramine; Cyproheptadine; Desipramine; Female; Fluphenazine; Humans; Imipramine; Male; Methyltyrosines; Pilocarpine; Pimozide; Promethazine; Rats; Reserpine; Spiperone

1976
Affinity profiles of pizotifen, ketotifen and other tricyclic antimuscarinics at muscarinic receptor subtypes M1, M2 and M3.
    European journal of pharmacology, 1992, Feb-18, Volume: 211, Issue:3

    Topics: (4-(m-Chlorophenylcarbamoyloxy)-2-butynyl)trimethylammonium Chloride; Animals; Cyproheptadine; Guinea Pigs; Ileum; Ketotifen; Kinetics; Male; Muscarinic Antagonists; Pizotyline; Promethazine; Rabbits; Receptors, Muscarinic; Structure-Activity Relationship; Trachea; Vas Deferens

1992
Inhibition of human and rabbit liver steroid and xenobiotic UDP-glucuronosyltransferases by tertiary amine drugs--implications for adverse drug reactions.
    Xenobiotica; the fate of foreign compounds in biological systems, 1992, Volume: 22, Issue:1

    Topics: Amines; Amitriptyline; Animals; Chlorpromazine; Cyproheptadine; Female; Glucuronosyltransferase; Gonadal Steroid Hormones; Humans; Imipramine; Microsomes, Liver; Molecular Structure; Promethazine; Rabbits; Testosterone

1992
Sedation and the stimulus properties of antihistamines.
    Pharmacology, biochemistry, and behavior, 1985, Volume: 22, Issue:1

    Topics: Animals; Chlorpheniramine; Conditioning, Operant; Cyproheptadine; Diphenhydramine; Dose-Response Relationship, Drug; Female; Histamine Antagonists; Histamine H1 Antagonists; Hypnotics and Sedatives; Promethazine; Rats; Rats, Inbred Strains

1985
Antihistaminic drugs increase feeding, while histidine suppresses feeding in rats.
    Pharmacology, biochemistry, and behavior, 1988, Volume: 31, Issue:1

    Topics: Animal Feed; Animals; Cyproheptadine; Diet; Doxepin; Energy Intake; Feeding Behavior; Food, Formulated; Histamine H1 Antagonists; Histidine; Male; Promethazine; Rats; Rats, Inbred Strains

1988
[The role of inflammation in the spontaneous elimination of Strongyloides ratti infestation].
    Annales de parasitologie humaine et comparee, 1986, Volume: 61, Issue:6

    Topics: Animals; Chlorpheniramine; Cyproheptadine; Indomethacin; Inflammation; Male; Nematode Infections; Promethazine; Rats; Rats, Inbred Strains; Sodium Salicylate; Stereoisomerism; Strongyloides; Strongyloidiasis

1986
Influence of various substances which induce and inhibit aggregation on the uptake of deoxyglucose by human blood platelets.
    The Journal of pharmacology and experimental therapeutics, 1974, Volume: 190, Issue:1

    Topics: Adenosine Diphosphate; Amitriptyline; Antidepressive Agents; Blood Glucose; Blood Platelets; Bucladesine; Carbon Radioisotopes; Chlorpromazine; Cyproheptadine; Desipramine; Epinephrine; Glucose; Humans; In Vitro Techniques; Norepinephrine; Nortriptyline; Platelet Adhesiveness; Promethazine; Serotonin; Thrombin

1974
Protection against ethanol-induced conditioned necrosis.
    Quarterly journal of studies on alcohol, 1968, Volume: 29, Issue:2

    Topics: Animals; Cyproheptadine; Ethanol; Female; Histamine H1 Antagonists; Injections, Intraperitoneal; Injections, Intravenous; Necrosis; Phenoxybenzamine; Promethazine; Rats; Serotonin Antagonists; Skin Diseases; Sodium Chloride

1968
Tremor induced by tremorine (1,4-dipyrrolidino but-2-yne) and its antagonism by certain antihistaminics.
    Indian journal of physiology and pharmacology, 1967, Volume: 11, Issue:4

    Topics: Animals; Atropine; Cyproheptadine; Female; Histamine H1 Antagonists; Hydrochloric Acid; Male; Promethazine; Rats; Sulfates; Tremor; Tremorine

1967
Activity of antihistamines in laboratory antidepressant tests.
    International journal of neuropharmacology, 1969, Volume: 8, Issue:1

    Topics: Amitriptyline; Animals; Anxiety; Blepharoptosis; Cyproheptadine; Drug Synergism; Histamine H1 Antagonists; Hostility; Humans; Hypothermia, Induced; Imipramine; Methamphetamine; Promethazine; Pyridines; Rats; Reserpine; Tetrabenazine; Tripelennamine

1969
An investigation of antihistaminic activity and gastric ulceration.
    European journal of pharmacology, 1969, Volume: 6, Issue:1

    Topics: Animals; Brompheniramine; Cyproheptadine; Female; Glycopyrrolate; Guinea Pigs; Histamine; Histamine H1 Antagonists; Male; Peptic Ulcer; Promethazine; Pylorus; Rats; Reserpine; Tripelennamine

1969
Effects of antihistamines on isolation-induced fighting in mice.
    Psychopharmacologia, 1971, Volume: 19, Issue:4

    Topics: Aggression; Animals; Behavior, Animal; Cyproheptadine; Diphenhydramine; Histamine H1 Antagonists; Humans; Ileum; Male; Mice; Motor Activity; Physostigmine; Promethazine; Social Isolation; Tetrabenazine

1971
Effects of various antihistamines on oxotremorine-induced hypothermia in mice.
    European journal of pharmacology, 1972, Volume: 17, Issue:1

    Topics: Alkynes; Analysis of Variance; Animals; Atropine; Benzyl Compounds; Chlorpheniramine; Cyproheptadine; Diphenhydramine; Ethylenediamines; Evaluation Studies as Topic; Histamine H1 Antagonists; Hypothermia; Male; Mice; Mice, Inbred Strains; Parasympathomimetics; Piperazines; Promethazine; Pyridines; Pyrrolidines; Pyrrolidinones; Tripelennamine

1972
[Studies on the strength of antihistaminic drugs in urticaria factitia patients using the dermographia test].
    Berufs-Dermatosen, 1972, Volume: 20, Issue:3

    Topics: Cyproheptadine; Histamine; Histamine H1 Antagonists; Humans; Promethazine; Skin Tests; Urticaria

1972
d-LSD binding to brain homogenates: possible relationship to serotonin receptors.
    Life sciences, 1974, Dec-01, Volume: 15, Issue:11

    Topics: Animals; Binding Sites; Binding, Competitive; Brain; Brain Chemistry; Cerebral Cortex; Chlorpromazine; Cyproheptadine; DOM 2,5-Dimethoxy-4-Methylamphetamine; Dose-Response Relationship, Drug; Hallucinogens; Imipramine; Lysergic Acid Diethylamide; Male; Methysergide; N,N-Dimethyltryptamine; Promethazine; Raphe Nuclei; Rats; Rats, Inbred Strains; Receptors, Drug; Receptors, Serotonin; Serotonin; Stereoisomerism; Subcellular Fractions; Tritium

1974
Urate crystal induced inflammation in the rat: evidence for the combined actions of kinins, histamine and components of complement.
    Immunological communications, 1972, Volume: 1, Issue:2

    Topics: Animals; Carboxypeptidases; Colchicine; Complement System Proteins; Cyproheptadine; Edema; Female; Gout; Histamine; Kinins; Male; Methysergide; Promethazine; Rats; Serotonin; Tripelennamine; Triprolidine; Trypsin Inhibitors; Uric Acid

1972
Binding of cyproheptadine-(N-methyl- 14 C) by human blood platelets: inhibition by phenothiazines and tricyclic antidepressants.
    The Journal of pharmacology and experimental therapeutics, 1973, Volume: 185, Issue:1

    Topics: Amitriptyline; Blood Platelets; Carbon Isotopes; Centrifugation; Chlorpromazine; Cyproheptadine; Desipramine; Humans; Imipramine; In Vitro Techniques; Nortriptyline; Phenothiazines; Platelet Adhesiveness; Promethazine

1973
Effect of steroidal and nonsteroidal anti-inflammatory compounds in a milkweed-sap-induced rat pedal edema.
    Steroids and lipids research, 1973, Volume: 4, Issue:1

    Topics: Animals; Anti-Inflammatory Agents; Aspirin; Biological Assay; Chlorpromazine; Cyproheptadine; Dexamethasone; Dose-Response Relationship, Drug; Edema; Enterobacteriaceae; Hindlimb; Hydrocortisone; Indomethacin; Male; Phenylbutazone; Plant Extracts; Plants; Promethazine; Rats; Time Factors

1973
Acute cutaneous necrosis following sensitization by heterologous blood.
    Medicina et pharmacologia experimentalis. International journal of experimental medicine, 1967, Volume: 16, Issue:3

    Topics: Acetates; Animals; Blood Group Incompatibility; Blood Transfusion; Cats; Cattle; Chlorpromazine; Cricetinae; Cyproheptadine; Dogs; Dopamine; Guinea Pigs; Histamine; Humans; Necrosis; Phenoxybenzamine; Poultry; Promethazine; Rabbits; Rats; Reserpine; Skin Diseases; Swine; Vasopressins

1967
Other pharmacologic agents that may affect bronchial hyperreactivity.
    The Journal of allergy and clinical immunology, 1984, Volume: 73, Issue:5 Pt 2

    Topics: Adrenergic alpha-Antagonists; Asthma; Asthma, Exercise-Induced; Benzothiazoles; Budesonide; Calcium Channel Blockers; Carbazoles; Chromones; Cyproheptadine; Humans; Ketotifen; Parasympatholytics; Piperazines; Pregnenediones; Promethazine; Thioxanthenes; Xanthines; Xanthones

1984
[Mechanism of action of certain fibrinolytic bis-tetrahydroisoquinolines: their antagonists and histamine- and 5-hydroxytryptamine-releasing effects (author's transl)].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1980, Volume: 76, Issue:1

    Topics: Animals; Cyproheptadine; Edema; Fibrinolysis; Fibrinolytic Agents; Histamine Release; Isoquinolines; Male; Phentolamine; Promethazine; Rats; Serotonin; Tetrahydroisoquinolines

1980
Discriminative stimulus properties of pizotifen maleate (BC105): a putative serotonin antagonist.
    Psychopharmacology, 1984, Volume: 83, Issue:2

    Topics: Animals; Cyproheptadine; Discrimination Learning; Generalization, Response; Lysergic Acid Diethylamide; Pizotyline; Promethazine; Rats; Rats, Inbred Strains; Thiophenes

1984
INHIBITION OF HISTAMINE RELEASE FROM MAST CELLS.
    Surgical forum, 1963, Volume: 14

    Topics: Anti-Allergic Agents; Cyproheptadine; Histamine H1 Antagonists; Histamine Release; Mast Cells; Pharmacology; Promethazine; Research; Surface-Active Agents; Trichloroacetic Acid

1963
THE EFFECT OF SOME NEW ANTIHISTAMINES ON THE ANAPHYLACTIC MICROSHOCK OF THE GUINEA-PIG.
    British journal of pharmacology and chemotherapy, 1963, Volume: 21

    Topics: Anaphylaxis; Animals; Anti-Allergic Agents; Antipsychotic Agents; Cyclic S-Oxides; Cyproheptadine; Guinea Pigs; Histamine H1 Antagonists; Methotrimeprazine; Pharmacology; Phenothiazines; Promethazine; Research; Trimeprazine

1963
EFFECT OF CYPROHEPTADINE ON A TOPICAL CALCIFICATION IN THE RAT.
    Canadian journal of physiology and pharmacology, 1964, Volume: 42

    Topics: Amidines; Ammonium Compounds; Calcification, Physiologic; Calcinosis; Cyproheptadine; Lysergic Acid Diethylamide; p-Methoxy-N-methylphenethylamine; Pathology; Pharmacology; Polymyxins; Promethazine; Protamines; Quaternary Ammonium Compounds; Rats; Research; Stilbamidines; Toxicology

1964
Pharmacological investigation of the nociceptive response and edema induced by venom of the scorpion Tityus serrulatus.
    Toxicon : official journal of the International Society on Toxinology, 2005, Volume: 45, Issue:5

    Topics: Analysis of Variance; Animals; Behavior, Animal; Cyproheptadine; Dipyrone; Edema; Indomethacin; Injections, Subcutaneous; Male; Mice; Morphine; Pain; Pain Threshold; Promethazine; Rats; Rats, Wistar; Scorpion Venoms; Scorpions; Serotonin

2005
Prolonged anticholinergic delirium following antihistamine overdose.
    Australasian psychiatry : bulletin of Royal Australian and New Zealand College of Psychiatrists, 2007, Volume: 15, Issue:3

    Topics: Adolescent; Cholinergic Antagonists; Cyproheptadine; Cytochrome P-450 CYP2D6 Inhibitors; Delirium; Drug Overdose; Female; Histamine H1 Antagonists; Humans; Promethazine; Time Factors

2007